A new case of hemoglobin Genova   2    2  28(B10) Leu leads to Pro. Further studies on the mechanism of instability and defective synthesis.
D000596:Amino Acids / Q000032:analysis; D001797:Blood Protein Electrophoresis; D002247:Carbon Isotopes; D002648:Child; D002852:Chromatography, Ion Exchange; D004355:Drug Stability; D004592:Electrophoresis, Starch Gel; D005826:Genetics, Medical; D006418:Heme; D006454:Hemoglobins / Q000302:isolation & purification; D006455:Hemoglobins, Abnormal / Q000096:biosynthesis / Q000302:isolation & purification; D006358:Hot Temperature; D006801:Humans; D007558:Italy; D007930:Leucine; D046911:Macromolecular Substances; D008297:Male; D009154:Mutation; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D010455:Peptides / Q000032:analysis; D011392:Proline; D012156:Reticulocytes / Q000378:metabolism
D000596:Amino Acids; D002247:Carbon Isotopes; D006454:Hemoglobins; D006455:Hemoglobins, Abnormal; D046911:Macromolecular Substances; D010455:Peptides; D006418:Heme; D011392:Proline; D007930:Leucine; D010100:Oxygen