SCH 10595, an effective dopamine- -hydroxylase inhibitor and a hypotensive agent.
D000577:Amides / Q000494:pharmacology*; D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000378:metabolism; D003900:Desoxycorticosterone / Q000037:antagonists & inhibitors; D004298:Dopamine / Q000378:metabolism; D004299:Dopamine beta-Hydroxylase / Q000037:antagonists & inhibitors*; D004305:Dose-Response Relationship, Drug; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000096:biosynthesis / Q000378:metabolism; D010848:Picolinic Acids / Q000494:pharmacology*; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013997:Time Factors
D000577:Amides; D000959:Antihypertensive Agents; D010848:Picolinic Acids; D003900:Desoxycorticosterone; D004299:Dopamine beta-Hydroxylase; D004298:Dopamine; D009638:Norepinephrine