Insect juvenile hormones: highly potent synthetic mimics.
The substitution of a 7-alkoxy group for the 6,7-epoxy moiety in aryl terpenoid ethers having high juvenile hormone activity has produced several compounds exceptionally active against Tenebrio molitor. The most potent compound [7-ethoxy-1-(p-ethylphenoxy)-3,7-dimethyl-2-octene, called JH-25] is active at the level of 10 picograms per insect, or about 100 times more active than other promising juvenile hormone mimics so far reported. Compound JH-25 was also active against Tribolium confusum.
D001681:Biological Assay; D055598:Chemical Phenomena; D002621:Chemistry; D007605:Juvenile Hormones / Q000494:pharmacology*; D013712:Tenebrio; D014231:Tribolium
D007605:Juvenile Hormones