title: Competitive binding of EF1 and EF2 by mammalian ribosomes: role of GTP hydrolysis in overcoming inhibition by EF2 of aminoacyl-tRNA binding.
mesh_terms: D000596:Amino Acids; D000818:Animals; D001426:Bacterial Proteins / Q000032:analysis; D001665:Binding Sites; D001667:Binding, Competitive; D002247:Carbon Isotopes; D002499:Centrifugation, Density Gradient; D006150:Guanine Nucleotides / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism*; D006868:Hydrolysis; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000166:cytology; D010445:Peptide Elongation Factors / Q000378:metabolism*; D012329:RNA, Bacterial; D012343:RNA, Transfer / Q000378:metabolism*; D051381:Rats; D012270:Ribosomes / Q000378:metabolism*; D013696:Temperature
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D002247:Carbon Isotopes; D006150:Guanine Nucleotides; D010445:Peptide Elongation Factors; D012329:RNA, Bacterial; D006160:Guanosine Triphosphate; D012343:RNA, Transfer; D007930:Leucine