The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole.
D000085:Acetates; D000096:Acetone; D000107:Acetylation; D000498:Allyl Compounds / Q000008:administration & dosage / Q000378:metabolism / Q000652:urine; D000812:Anhydrides; D000818:Animals; D001965:Bromides; D002247:Carbon Isotopes; D002273:Carcinogens / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D004149:Dioxoles / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D004563:Electrochemistry; D005966:Glucuronidase / Q000494:pharmacology; D006150:Guanine Nucleotides; D006168:Guinea Pigs; D006900:Hydroxylation; D007274:Injections, Intraperitoneal; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D013058:Mass Spectrometry; D008715:Methionine; D008722:Methods; D009705:Nucleosides; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D013388:Succinimides; D014316:Tritium; D014466:Ultraviolet Rays
D000085:Acetates; D000498:Allyl Compounds; D000812:Anhydrides; D001965:Bromides; D002247:Carbon Isotopes; D002273:Carcinogens; D004149:Dioxoles; D006150:Guanine Nucleotides; D009705:Nucleosides; D013388:Succinimides; D014316:Tritium; D000096:Acetone; D008715:Methionine; D005966:Glucuronidase; D010634:Phenobarbital