Report of vascilitis and blindness after intracarotid injection of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) in dogs.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001766:Blindness / Q000139:chemically induced*; D001932:Brain Neoplasms / Q000188:drug therapy; D002339:Carotid Arteries / Q000473:pathology; D003315:Cornea / Q000473:pathology; D003318:Corneal Opacity / Q000139:chemically induced / Q000473:pathology; D004285:Dogs; D005260:Female; D006400:Hematocrit; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D008297:Male; D009607:Nitrosourea Compounds / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D013997:Time Factors; D014652:Vascular Diseases / Q000139:chemically induced* / Q000473:pathology
D009607:Nitrosourea Compounds