Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide.
D000447:Aldehydes / Q000097:blood / Q000652:urine; D000477:Alkylating Agents / Q000097:blood / Q000652:urine; D000818:Animals; D002855:Chromatography, Thin Layer; D003520:Cyclophosphamide / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism*; D008954:Models, Biological; D009578:Nitrobenzenes / Q000378:metabolism; D011725:Pyridines / Q000378:metabolism; D051381:Rats; D012664:Semicarbazones / Q000032:analysis
D000447:Aldehydes; D000477:Alkylating Agents; D009578:Nitrobenzenes; D011725:Pyridines; D012664:Semicarbazones; D003520:Cyclophosphamide