Insensitivity of bacteria to proposed antimetabolites of D-alanyl-D-alanine.
alpha-Aminoisobutyryl-d-alanine, d-alanyl-alpha-aminoisobutyric acid, and alpha-amino-isobutyryl-alpha-aminoisobutyric acid, proposed as antimetabolites of d-alanyl-d-alanine in bacterial cell wall synthesis, failed to inhibit bacterial growth.
D000409:Alanine / Q000494:pharmacology*; D000621:Aminoisobutyric Acids / Q000494:pharmacology; D000963:Antimetabolites / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004151:Dipeptides / Q000494:pharmacology; D004352:Drug Resistance, Microbial
D000621:Aminoisobutyric Acids; D000963:Antimetabolites; D004151:Dipeptides; C002956:alanylalanine; D000409:Alanine