Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.
D000215:Acylation; D000409:Alanine; D000813:Anilides; D001565:Benzoates; D001667:Binding, Competitive; D055598:Chemical Phenomena; D002621:Chemistry; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D004126:Dimethylformamide; D004590:Electrophoresis, Paper; D004952:Esters; D005998:Glycine; D006834:Hydrazines; D006868:Hydrolysis; D007700:Kinetics; D008433:Mathematics; D008738:Methyl Ethers; D009578:Nitrobenzenes; D009994:Osmolar Concentration; D010455:Peptides; D010649:Phenylalanine; D000644:Quaternary Ammonium Compounds; D013329:Structure-Activity Relationship; D013816:Thermodynamics; D014316:Tritium
D000813:Anilides; D001565:Benzoates; D004952:Esters; D006834:Hydrazines; D008738:Methyl Ethers; D009578:Nitrobenzenes; D010455:Peptides; D000644:Quaternary Ammonium Compounds; D014316:Tritium; D010649:Phenylalanine; D004126:Dimethylformamide; D002918:Chymotrypsin; D000409:Alanine; D005998:Glycine