title: Halophilic bacteria susceptibility to peracetic acid vapor and ethylene oxide.
abstract: Extremely to slightly halophilic bacteria were tested for susceptibility to two sterilizing agents, peracetic acid (PAA) and ethylene oxide (ETO). PAA susceptibility was explored by two methods: an agar plate (constant pH of 7.2) and a filter strip (constant incubation period of 37 days); 100% susceptibility was obtained by both methods. The dosage (0.5 ml/min) was applied to a filter pad in a petri dish cover. Glove box experiments with ETO (input 1.5 lb. [ca. 680.4 g]/24 hr, the only constant) yielded 100% susceptibility for all halophiles tested. These experiments demonstrated the efficacy of two lethal agents for extreme halophiles, PAA and ETO. Variation in pH did not affect susceptibility.
mesh_terms: D000085:Acetates / Q000494:pharmacology*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D005027:Ethylene Oxide / Q000494:pharmacology*; D005417:Flavobacterium / Q000187:drug effects* / Q000254:growth & development; D006217:Halobacterium / Q000187:drug effects* / Q000254:growth & development; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D008837:Micrococcus / Q000187:drug effects* / Q000254:growth & development; D011549:Pseudomonas / Q000187:drug effects* / Q000254:growth & development; D012965:Sodium Chloride / Q000494:pharmacology*; D013242:Sterilization; D013696:Temperature
chemical_list: D000085:Acetates; D003470:Culture Media; D012965:Sodium Chloride; D005027:Ethylene Oxide