Peritoneal dialysis solutions.
Certain preventable complications in the treatment of renal failure, in part related to the composition of commercially prepared peritoneal dialysis solutions, continue to occur.Solutions are advocated which would contain sodium 132, calcium 3.5, magnesium 1.5, chloride 102 and lactate or acetate 35 mEq./1., and dextrose 1.5% or about 4.25%. Elimination of 7% dextrose solutions and a reduction of the sodium and lactate concentrations should reduce complications due to hypovolemia, hyperglycemia, hypernatremia and alkalosis. Reduction in the number of solutions should simplify the procedure and perhaps reduce costs. It is anticipated that some of the changes discussed will soon be introduced by industry.
D000085:Acetates / Q000008:administration & dosage; D058186:Acute Kidney Injury / Q000628:therapy; D001806:Blood Urea Nitrogen; D002118:Calcium / Q000008:administration & dosage; D002712:Chlorides / Q000008:administration & dosage; D003128:Coma / Q000139:chemically induced; D005947:Glucose / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced; D006955:Hypernatremia / Q000139:chemically induced; D007676:Kidney Failure, Chronic / Q000628:therapy; D007773:Lactates / Q000008:administration & dosage; D008274:Magnesium / Q000008:administration & dosage; D010530:Peritoneal Dialysis / Q000009:adverse effects; D011188:Potassium / Q000008:administration & dosage; D012964:Sodium / Q000008:administration & dosage / Q000009:adverse effects; D013012:Sorbitol / Q000008:administration & dosage / Q000009:adverse effects
D000085:Acetates; D002712:Chlorides; D007773:Lactates; D013012:Sorbitol; D012964:Sodium; D008274:Magnesium; D005947:Glucose; D011188:Potassium; D002118:Calcium