title: Photoreactivation of ultraviolet-induced chromosomal aberrations.
abstract: Ultraviolet induces only chromatid-type aberrations in synchronized G(1) V-79 Chinese hamster and A8W243 Xenopus tissue culture cells. Posttreatment with white light prevents expression of most potential aberrations in the A8 toad cell, which possesses a photoreactivation enzyme. We conclude that the major ultraviolet-induced DNA lesion leading to chromosomal aberrations is the pyrimidine dimer.
mesh_terms: D000818:Animals; D002460:Cell Line; D002477:Cells / Q000201:enzymology; D002842:Chromatids / Q000528:radiation effects; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects*; D003036:Cobalt Isotopes; D006224:Cricetinae; D004247:DNA / Q000528:radiation effects; D004260:DNA Repair; D008190:Lyases; D008938:Mitosis / Q000528:radiation effects; D010777:Photochemistry; D011742:Pyrimidine Nucleotides / Q000528:radiation effects; D011743:Pyrimidines; D011830:Radiation Effects; D014466:Ultraviolet Rays; D014981:Xenopus
chemical_list: D003036:Cobalt Isotopes; D011742:Pyrimidine Nucleotides; D011743:Pyrimidines; D004247:DNA; D008190:Lyases