title: Mechanism of warfarin resistance. Warfarin and the metabolism of vitamin K 1 .
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004351:Drug Resistance; D005260:Female; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008297:Male; D009154:Mutation; D010087:Oxides / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D011516:Prothrombin / Q000096:biosynthesis / Q000097:blood; D011517:Prothrombin Time; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D012964:Sodium / Q000494:pharmacology; D013045:Species Specificity; D014316:Tritium; D010837:Vitamin K 1 / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000494:pharmacology; D014859:Warfarin / Q000494:pharmacology*
chemical_list: D010087:Oxides; D014316:Tritium; D014859:Warfarin; D010837:Vitamin K 1; D011516:Prothrombin; D012964:Sodium