title: Lead intoxication in children in Birmingham.
abstract: Of 38 children investigated between 1966 and 1971 who had a blood lead concentration greater than 37 mug/100 ml eight had encephalopathy and one died; all these eight had a blood lead concentration of 99 mug/100 ml or above. Blood lead levels are related to haemoglobin concentrations and anaemia is common in children with blood lead concentrations of 37-60 mug/100 ml, levels previously accepted as harmless.Children with blood lead concentrations greater than 60 mug/100 ml show radiological evidence of lead intoxication, and treatment for this should be considered when blood lead concentration exceeds 37 mug/100 ml. Children presenting with unexplained encephalopathy should be radiographed for evidence of lead intoxication.
mesh_terms: D000740:Anemia / Q000150:complications; D001927:Brain Diseases / Q000139:chemically induced; D002675:Child, Preschool; D004739:England; D006452:Hemoglobinometry; D006801:Humans; D007223:Infant; D007717:Knee / Q000000981:diagnostic imaging; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology; D011859:Radiography; D012621:Seasons
chemical_list: D007854:Lead