Abnormal excretion of corticosteroid sulphates in patients with breast cancer.
In a preliminary study, the 24-hour urinary excretion of corticosteroid sulphates and free cortisol have been measured in a group of patients with breast cancer and compared with the excretion of the same compounds in a group of normal women of similar age. Excretion of corticosteroid sulphates in the breast cancer group was found to be markedly raised. In a small number of patients with localized cancer of sites other than the breast the level of corticosteroid sulphate was not raised. If proved metastases were present a noticeable rise was observed.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000652:urine*; D003345:Corticosterone / Q000652:urine*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000652:urine; D011869:Radioligand Assay; D013223:Statistics as Topic; D013431:Sulfates / Q000652:urine*; D013997:Time Factors
D013431:Sulfates; D003345:Corticosterone; D006854:Hydrocortisone