A major genetic locus affecting resistance to infection with murine leukemia viruses. 3. Assignment of the Fv-1 locus to linkage group 8 of the mouse.
The Fv-1 gene, which regulates sensitivity of mouse cells to infection by naturally occurring host-range types of murine leukemia virus, was shown to be located on linkage group VIII (chromosome 4), 39 map units from b.
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D003116:Color; D003433:Crosses, Genetic; D005622:Friend murine leukemia virus / Q000276:immunology* / Q000302:isolation & purification; D005796:Genes; D008040:Genetic Linkage; D006197:Hair; D006824:Hybridization, Genetic; D007109:Immunity; D007125:Immunogenetics; D007942:Leukemia, Experimental / Q000209:etiology / Q000276:immunology*; D051379:Mice; D013154:Spleen / Q000382:microbiology