Evidence that the goitrogen, methimazole, interferes with the extrathyroidal utilization of exogenous thyroxine.
D000818:Animals; D001681:Biological Assay; D001835:Body Weight / Q000187:drug effects; D004032:Diet; D007668:Kidney / Q000201:enzymology; D008297:Male; D008713:Methimazole / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D013961:Thyroid Gland / Q000502:physiology; D013974:Thyroxine / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism
D008713:Methimazole; D000637:Transaminases; D013974:Thyroxine