title: Relationship of drinking water quality (hardness-softness) to cardiovascular mortality in Newfoundland.
abstract: The profile of mortality in Newfoundland was analysed for all deaths occurring in 1969 of persons 35 to 69 years of age, of whom the total was 1036. An exceptionally high cardiovascular mortality (793 deaths/100,000) was noted for St. John's, the capital city of Newfoundland, a city which has an extremely soft drinking-water supply. This high rate corresponds to that observed in the "high mortality belt" reported for the east coast of the United States, and in conjunction with data from mainland Canada, extends the belt across the entire eastern aspect of North America. The proportion of cardiovascular deaths of men occurring outside the hospital was less within hard drinking-water areas in Newfoundland than in the soft water areas of the province. Thus, the statistics reported here of cardiovascular mortality confirm evidence reported elsewhere on "macro-geographic" variations in this disease(s) as well as "micro-geographic" regional variations which may be dependent upon local environmental factors.
mesh_terms: D000328:Adult; D000368:Aged; D001639:Bicarbonates / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D002318:Cardiovascular Diseases / Q000145:classification / Q000209:etiology / Q000401:mortality*; D002712:Chlorides / Q000494:pharmacology; D005260:Female; D006321:Heart / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000401:mortality; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D009523:Newfoundland and Labrador; D012214:Rheumatic Heart Disease / Q000401:mortality; D012964:Sodium / Q000494:pharmacology; D013431:Sulfates / Q000494:pharmacology; D014880:Water Softening; D014881:Water Supply
chemical_list: D001639:Bicarbonates; D002712:Chlorides; D013431:Sulfates; D012964:Sodium; D008274:Magnesium; D002118:Calcium