Urinary catecholamine metabolites during behavioral changes in a patient with manic-depressive cycles.
3-Methoxy-4-hydroxyphenylglycol and normetanephrine were analyzed in daily urine specimens of a patient with manic-depressive cycles who was studied longitudinally. The quantities of these catecholamine metabolites excreted into urine were decreased during periods of depression as compared with periods of mania. Urinary excretion of 3-methoxy-4-hydroxyphenylglycol varied cyclically with a period length of approximately 20 days. Changes in this metabolite, and perhaps in normetanephrine, preceded the affective and behavioral shifts.
D001714:Bipolar Disorder / Q000652:urine*; D002395:Catecholamines / Q000652:urine*; D002396:Catechols / Q000652:urine; D005260:Female; D006018:Glycols / Q000652:urine; D006801:Humans; D008875:Middle Aged; D009647:Normetanephrine / Q000652:urine; D010507:Periodicity
D002395:Catecholamines; D002396:Catechols; D006018:Glycols; D009647:Normetanephrine