Assessment of the 14C-glycocholic acid breath test.
The 1-((14)C)-glycine-glycocholic-acid breath test has been performed on 104 subjects and a normal range established. Abnormal results due to bacterial deconjugation of bile salts were found not only in patients with the "contaminated bowel" syndrome and in those with ileal resection but also in a third group, patients with cholangitis. Abnormal results were also found in patients with gastrocolic fistula and staphylococcal enterocolitis, while mildly abnormal results were also found in some patients with liver disease.
D001419:Bacteria / Q000378:metabolism; D001424:Bacterial Infections / Q000175:diagnosis*; D001647:Bile Acids and Salts; D001765:Blind Loop Syndrome / Q000175:diagnosis; D002245:Carbon Dioxide / Q000032:analysis / Q000378:metabolism; D002247:Carbon Isotopes; D002761:Cholangitis / Q000382:microbiology; D005188:False Negative Reactions; D005189:False Positive Reactions; D005998:Glycine / Q000378:metabolism; D006000:Glycocholic Acid / Q000378:metabolism; D006801:Humans; D007082:Ileum / Q000382:microbiology; D007421:Intestine, Small / Q000382:microbiology*; D007583:Jejunum / Q000382:microbiology; D008107:Liver Diseases / Q000382:microbiology
D001647:Bile Acids and Salts; D002247:Carbon Isotopes; D002245:Carbon Dioxide; D006000:Glycocholic Acid; D005998:Glycine