Stereochemical studies on medicinal agents. 13. Correlation of the solid-state conformations of 1,3,5-trimethyl- and 1,3-dimethyl-4-phenyl-4-propionoxypiperidine enantiomers with their absolute stereoselectivity at analgetic receptors.
D000522:Alphaprodine / Q000138:chemical synthesis / Q000494:pharmacology*; D000700:Analgesics / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D003461:Crystallography; D004305:Dose-Response Relationship, Drug; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008745:Methylation; D051379:Mice; D008961:Models, Structural; D008968:Molecular Conformation; D009020:Morphine / Q000494:pharmacology; D009904:Optical Rotation; D011930:Reaction Time / Q000187:drug effects; D011955:Receptors, Drug / Q000187:drug effects*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000700:Analgesics; D011955:Receptors, Drug; D000522:Alphaprodine; D009020:Morphine