title: Hepatotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. (CCNU) in dogs: the use of serial percutaneous liver biopsies.
mesh_terms: D000284:Administration, Oral; D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D001706:Biopsy; D001835:Body Weight / Q000187:drug effects; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003510:Cyclohexanes / Q000494:pharmacology / Q000633:toxicity; D004285:Dogs; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D006651:Histocytochemistry; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008111:Liver Function Tests; D008297:Male; D009607:Nitrosourea Compounds / Q000008:administration & dosage / Q000494:pharmacology / Q000633:toxicity*; D013448:Sulfobromophthalein; D013997:Time Factors
chemical_list: D003510:Cyclohexanes; D009607:Nitrosourea Compounds; D013448:Sulfobromophthalein; D000410:Alanine Transaminase