Evaluation of streptozyme and antistreptolysin O tests in streptococcal pyodermal nephritis.
The evaluation of the streptozyme test in sera from 34 patients with streptococcal pyodermal nephritis was studied. Ninety-seven percent of the patients developed high titers of antistreptozyme antibodies on the first bleeding after hospitalization, in contrast to only 40% of patients who developed elevated antistreptolysin O titers. The high antistreptozyme titers declined during convalescence and reached normal levels in the sixth month after onset of the disease. The most significant fall in titers occurred between 1 and 2 months from the onset of disease. The streptozyme test may be particularly helpful as a rapid screening test for antibodies in streptococcal pyodermal nephritis.
D000293:Adolescent; D000906:Antibodies / Q000032:analysis; D000989:Antistreptolysin / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003851:Deoxyribonucleases; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D006801:Humans; D006821:Hyaluronoglucosaminidase; D008722:Methods; D009699:N-Glycosyl Hydrolases; D009393:Nephritis / Q000175:diagnosis* / Q000209:etiology; D011711:Pyoderma / Q000150:complications; D012698:Serologic Tests; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000209:etiology; D013291:Streptococcus / Q000201:enzymology; D013300:Streptokinase; D013997:Time Factors
D000906:Antibodies; D000989:Antistreptolysin; D003851:Deoxyribonucleases; D006821:Hyaluronoglucosaminidase; D009699:N-Glycosyl Hydrolases; D013300:Streptokinase