title: 3- (16Beta,17beta-dihydroxy-3-oxoandrost-4-en-17alpha-yl) propionic acid gamma-lactone, its preparation and antimineralocorticoid activity.
mesh_terms: D000315:Adrenalectomy; D000731:Androstanes / Q000138:chemical synthesis*; D000736:Androstenes / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D003900:Desoxycorticosterone / Q000037:antagonists & inhibitors; D004231:Diuresis / Q000187:drug effects; D007664:Ketosteroids / Q000138:chemical synthesis / Q000494:pharmacology; D007783:Lactones / Q000138:chemical synthesis / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists; D008901:Mineralocorticoids / Q000037:antagonists & inhibitors*; D011188:Potassium / Q000652:urine; D051381:Rats; D012964:Sodium / Q000652:urine; D013148:Spironolactone / Q000494:pharmacology
chemical_list: D000731:Androstanes; D000736:Androstenes; D007664:Ketosteroids; D007783:Lactones; D000451:Mineralocorticoid Receptor Antagonists; D008901:Mineralocorticoids; D013148:Spironolactone; D003900:Desoxycorticosterone; D012964:Sodium; D011188:Potassium