Zinc: a trace element essential in vitamin A metabolism.
Zinc is necessary to maintain normal concentrations of vitamin A in plasma. By using animals deficient in both zinc and vitamin A, it was demonstrated that zinc is necessary for normal mobilization of vitamin A from the liver. These results suggest that cases of depressed vitamin A in plasma, unresponsive to vitamin A therapy, may respond to zinc supplementation.
D000818:Animals; D003677:Deficiency Diseases / Q000378:metabolism; D004032:Diet; D008099:Liver / Q000378:metabolism; D051381:Rats; D014801:Vitamin A / Q000097:blood / Q000378:metabolism*; D014802:Vitamin A Deficiency / Q000378:metabolism; D015032:Zinc / Q000378:metabolism / Q000502:physiology*
D014801:Vitamin A; D015032:Zinc