The disposition of propranolol. IV. A dominant role for tissue uptake in the dose-dependent extraction of propranolol by the perfused rat liver.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D010477:Perfusion; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011433:Propranolol / Q000097:blood / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D011433:Propranolol; D011335:Proadifen; D010634:Phenobarbital