Overcoming some limiting factors in tumour immunotherapy.
Immunotherapy using rat 7s antibodies against plasmacytoma 5563 in C3H mice has been measured carefully. Prior adsorption of antibodies with normal mouse tissues, and supplements of co-optable non-immunized macrophages and lymphocytes enhanced the scope of immunotherapy against established tumours. It is suggested that available co-optable lymphocytes and macrophages are imporant limiting factors in tumour immunotherapy.
D000327:Adsorption; D000818:Animals; D000912:Antibodies, Neoplasm; D005260:Female; D007104:Immune Adherence Reaction; D007167:Immunotherapy; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000628:therapy; D010954:Plasmacytoma / Q000628:therapy*; D051381:Rats
D000912:Antibodies, Neoplasm