Induction by an hepatic carcinogen, 1-nitroso-5,6-dihydrouracil, of single and double strand breaks of liver DNA with rapid repair.
D000818:Animals; D002273:Carcinogens / Q000494:pharmacology*; D002499:Centrifugation, Density Gradient; D002956:Citrulline / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis* / Q000378:metabolism; D004260:DNA Repair / Q000187:drug effects; D004277:DNA, Single-Stranded; D004305:Dose-Response Relationship, Drug; D006498:Hepatectomy; D006827:Hydantoins / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D008115:Liver Regeneration; D008297:Male; D008970:Molecular Weight; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors; D014316:Tritium; D014498:Uracil / Q000494:pharmacology
D002273:Carcinogens; D004277:DNA, Single-Stranded; D006827:Hydantoins; D009607:Nitrosourea Compounds; D014316:Tritium; D002956:Citrulline; D014498:Uracil; D004247:DNA