Effect of penicillin on the increase in membrane conductance induced by gamma-aminobutyric acid at the crab neuromuscular junction.
The effects of penicillin and picrotoxin on the increase in membrane conductance produced by gamma-aminobutyric acid (GABA) at the hermit crab neuromuscular junction were investigated. Penicillin failed to block the effects of GABA, while picrotoxin proved to be a potent antagonist.
D000613:Aminobutyrates / Q000494:pharmacology*; D000818:Animals; D003386:Brachyura; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004558:Electric Stimulation; D066298:In Vitro Techniques; D008566:Membranes / Q000187:drug effects*; D009132:Muscles / Q000187:drug effects; D009431:Neural Conduction / Q000187:drug effects*; D009469:Neuromuscular Junction / Q000187:drug effects*; D010400:Penicillin G / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology*; D010852:Picrotoxin / Q000494:pharmacology
D000613:Aminobutyrates; D010400:Penicillin G; D010406:Penicillins; D010852:Picrotoxin