Recombinant inbred lines: value in the genetic analysis of biochemical variants.
Analysis of inducibility by androgens and electrophoretic mobility of kidney glucuronidase in progenitor and derived recombinant inbred mouse lines suggests that a single major regulatory gene at or near the glucuronidase structural gene on chromosome 5 determines the rate of enzyme accumulation.
D000818:Animals; D002874:Chromosome Mapping; D004586:Electrophoresis; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D005796:Genes; D005809:Genes, Regulator; D008040:Genetic Linkage; D005966:Glucuronidase / Q000032:analysis / Q000096:biosynthesis*; D007668:Kidney / Q000201:enzymology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D009876:Operon; D011995:Recombination, Genetic; D013739:Testosterone / Q000494:pharmacology
D013739:Testosterone; D005966:Glucuronidase