Smooth muscle regeneration in the ureter. Electron microscopic and autoradiographic observations.
The cellular events taking place during reconstitution of the rabbit ureteral wall following resection of a portion of its circumference were studied utilizing electron microscopy and autoradiography. It was shown that hyperplasia takes place in the smooth muscle of the ureteral remnant during the first 2 postoperative weeks and that spindle-shaped cells possessing the ultrastructural characteristics of myoblasts migrate from the edges of the remnant into the defect, resulting in regeneration of the muscularis within 5 to 6 weeks of the time of injury.
D000818:Animals; D001345:Autoradiography; D003094:Collagen; D004721:Endoplasmic Reticulum; D004848:Epithelium / Q000502:physiology; D005347:Fibroblasts; D006056:Golgi Apparatus; D008264:Macrophages; D008854:Microscopy, Electron; D009130:Muscle, Smooth / Q000166:cytology / Q000502:physiology*; D009392:Nephrectomy; D009504:Neutrophils; D011817:Rabbits; D012038:Regeneration; D013936:Thymidine; D013997:Time Factors; D014316:Tritium; D014513:Ureter / Q000502:physiology* / Q000601:surgery; D001743:Urinary Bladder / Q000502:physiology
D014316:Tritium; D003094:Collagen; D013936:Thymidine