Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo.
D000171:Acrolein / Q000627:therapeutic use; D000818:Animals; D001681:Biological Assay; D002279:Carcinoma 256, Walker / Q000188:drug therapy; D002470:Cell Survival; D002699:Chlorambucil / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use / Q000652:urine; D007274:Injections, Intraperitoneal; D008297:Male; D008466:Mechlorethamine / Q000627:therapeutic use; D008862:Microsomes, Liver / Q000201:enzymology; D009368:Neoplasm Transplantation; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D014184:Transplantation, Homologous
D002699:Chlorambucil; D008466:Mechlorethamine; D000171:Acrolein; D003520:Cyclophosphamide; D010634:Phenobarbital