Role of cytochrome P-450 in carbon tetrachloride activation and CCl 4-induced necrosis. Effect of inhibitors of heme synthesis. I. 3-Amino-1,2,4 triazole.
D000818:Animals; D002247:Carbon Isotopes; D002251:Carbon Tetrachloride / Q000494:pharmacology; D002252:Carbon Tetrachloride Poisoning / Q000201:enzymology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004347:Drug Interactions; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D006418:Heme / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D009336:Necrosis / Q000473:pathology; D009929:Organ Size; D010634:Phenobarbital / Q000494:pharmacology; D014230:Triazoles / Q000494:pharmacology*
D002247:Carbon Isotopes; D014230:Triazoles; D006418:Heme; D003577:Cytochrome P-450 Enzyme System; D002251:Carbon Tetrachloride; D010634:Phenobarbital