Discordance for childhood coeliac disease in monozygotic twins.
Discordance for childhood coeliac disease in monozygotic twin boys is reported. The diagnosis of coeliac disease in the second-born twin was established by demonstration of a flat small intestinal mucosa on biopsy and a clinical response to a gluten-free diet. The first-born twin had a normal small intestinal mucosa. Phenotypic, genotypic, and dermatoglyphic observations as well as gross observation of the placenta and membranes provided strong evidence that these twin boys were monozygotic.
D001789:Blood Group Antigens; D002446:Celiac Disease / Q000235:genetics*; D003878:Dermatoglyphics; D004200:Diseases in Twins; D005826:Genetics, Medical; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male
D001789:Blood Group Antigens