The convulsant potency of lidocaine and its N-dealkylated metabolites.
D000083:Acetanilides / Q000494:pharmacology; D000588:Amines / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003640:Dealkylation; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005021:Ethylamines / Q000494:pharmacology; D007928:Lethal Dose 50; D008012:Lidocaine / Q000097:blood / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D013058:Mass Spectrometry; D051381:Rats; D012640:Seizures / Q000139:chemically induced*; D014992:Xylenes / Q000494:pharmacology
D000083:Acetanilides; D000588:Amines; D005021:Ethylamines; D014992:Xylenes; D008012:Lidocaine