Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Specificity of the S-adenosylhomocysteine binding site.
D000241:Adenosine / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites / Q000187:drug effects; D065098:Catechol O-Methyltransferase Inhibitors; D005461:Fluorine; D006710:Homocysteine / Q000138:chemical synthesis* / Q000494:pharmacology; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D011485:Protein Binding / Q000187:drug effects; D051381:Rats; D013816:Thermodynamics
D065098:Catechol O-Methyltransferase Inhibitors; D006710:Homocysteine; D005461:Fluorine; D008780:Methyltransferases; D000241:Adenosine