title: Overcoming some limiting factors in tumour immunotherapy.
abstract: Immunotherapy using rat 7s antibodies against plasmacytoma 5563 in C3H mice has been measured carefully. Prior adsorption of antibodies with normal mouse tissues, and supplements of co-optable non-immunized macrophages and lymphocytes enhanced the scope of immunotherapy against established tumours. It is suggested that available co-optable lymphocytes and macrophages are imporant limiting factors in tumour immunotherapy.
mesh_terms: D000327:Adsorption; D000818:Animals; D000912:Antibodies, Neoplasm; D005260:Female; D007104:Immune Adherence Reaction; D007167:Immunotherapy; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000628:therapy; D010954:Plasmacytoma / Q000628:therapy*; D051381:Rats
chemical_list: D000912:Antibodies, Neoplasm