title: Potent competitive uricase inhibitors--2,8-diazahypoxanthine and related compounds.
mesh_terms: D000481:Allantoin / Q000097:blood; D000818:Animals; D001372:Aza Compounds / Q000138:chemical synthesis / Q000494:pharmacology; D001375:Azaguanine / Q000494:pharmacology; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D006147:Guanine; D007042:Hypoxanthines / Q000138:chemical synthesis / Q000494:pharmacology*; D066298:In Vitro Techniques; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D010430:Pentosyltransferases / Q000037:antagonists & inhibitors; D011720:Pyrazoles / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014503:Urate Oxidase / Q000037:antagonists & inhibitors*; D014527:Uric Acid / Q000097:blood; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors; D014970:Xanthines / Q000494:pharmacology
chemical_list: D001372:Aza Compounds; D007042:Hypoxanthines; D011720:Pyrazoles; D014970:Xanthines; D014527:Uric Acid; D000481:Allantoin; D006147:Guanine; D014969:Xanthine Oxidase; D014503:Urate Oxidase; D010430:Pentosyltransferases; D001375:Azaguanine