Model studies of thymidylate synthetase. Intramolecular catalysis of 5-hydrogen exchange and 5-hydroxymethylation of 1-substituted uracils.
D000080:Acetals; D002247:Carbon Isotopes; D002384:Catalysis; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D003857:Deoxyuridine; D003903:Deuterium; D004988:Ethers, Cyclic; D005492:Folic Acid; D006859:Hydrogen; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008780:Methyltransferases; D008956:Models, Chemical; D011522:Protons; D011744:Pyrimidinones; D012263:Ribonucleosides; D013056:Spectrophotometry, Ultraviolet; D013763:Tetrahydrofolates; D013940:Thymidylate Synthase; D014316:Tritium; D014498:Uracil; D014529:Uridine
D000080:Acetals; D002247:Carbon Isotopes; D004988:Ethers, Cyclic; D011522:Protons; D011744:Pyrimidinones; D012263:Ribonucleosides; D013763:Tetrahydrofolates; D014316:Tritium; D014498:Uracil; D006859:Hydrogen; D005492:Folic Acid; D003903:Deuterium; D008780:Methyltransferases; D013940:Thymidylate Synthase; D003857:Deoxyuridine; D014529:Uridine