Role of glutamine in purine synthesis and in guanine nucleotide formation in normal fibroblasts and in fibroblasts deficient in hypoxanthine phosphoribosyltransferase activity.
D000225:Adenine / Q000378:metabolism; D002247:Carbon Isotopes; D002478:Cells, Cultured; D005347:Fibroblasts / Q000201:enzymology / Q000378:metabolism; D005561:Formates / Q000378:metabolism; D005973:Glutamine / Q000378:metabolism* / Q000494:pharmacology; D006150:Guanine Nucleotides / Q000096:biosynthesis*; D006801:Humans; D007042:Hypoxanthines / Q000378:metabolism; D007926:Lesch-Nyhan Syndrome / Q000201:enzymology*; D010430:Pentosyltransferases / Q000378:metabolism*; D011687:Purines / Q000096:biosynthesis*; D013997:Time Factors
D002247:Carbon Isotopes; D005561:Formates; D006150:Guanine Nucleotides; D007042:Hypoxanthines; D011687:Purines; D005973:Glutamine; D010430:Pentosyltransferases; D000225:Adenine