title: Effects of thiamin antagonists on drug hydroxylation and properties of cytochrome P-450 in the rat.
mesh_terms: D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology*; D001667:Binding, Competitive; D001835:Body Weight / Q000187:drug effects; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006591:Hexobarbital / Q000378:metabolism; D006900:Hydroxylation; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009929:Organ Size; D011506:Proteins / Q000378:metabolism; D011743:Pyrimidines / Q000494:pharmacology; D051381:Rats; D013831:Thiamine / Q000037:antagonists & inhibitors*; D013844:Thiazoles / Q000494:pharmacology*
chemical_list: D000814:Aniline Compounds; D000963:Antimetabolites; D065607:Cytochrome P-450 Enzyme Inhibitors; D011506:Proteins; D011743:Pyrimidines; D013844:Thiazoles; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D006899:Mixed Function Oxygenases; D013831:Thiamine