Study of the therapeutic and toxic effects of ouabain by simultaneous observations on the excised and blood-perfused sinoatrial node and papillary muscle preparations and the in situ heart of dogs.
D000311:Adrenal Glands / Q000502:physiology; D000315:Adrenalectomy; D000758:Anesthesia; D000818:Animals; D004285:Dogs; D004562:Electrocardiography; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D007928:Lethal Dose 50; D009020:Morphine / Q000494:pharmacology; D009132:Muscles / Q000187:drug effects*; D010042:Ouabain / Q000494:pharmacology / Q000627:therapeutic use / Q000633:toxicity; D010210:Papillary Muscles / Q000187:drug effects; D010424:Pentobarbital / Q000494:pharmacology; D010477:Perfusion; D012849:Sinoatrial Node / Q000187:drug effects*; D013610:Tachycardia / Q000139:chemically induced; D013997:Time Factors; D014520:Urethane / Q000494:pharmacology; D014693:Ventricular Fibrillation / Q000139:chemically induced
D014520:Urethane; D010042:Ouabain; D009020:Morphine; D010424:Pentobarbital