Differential cell permeability and the basis for selective activity of methotrexate during therapy of the L1210 leukemia.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003857:Deoxyuridine / Q000378:metabolism; D007274:Injections, Intraperitoneal; D007279:Injections, Subcutaneous; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D010537:Peritoneum; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis; D014184:Transplantation, Homologous; D014316:Tritium
D004273:DNA, Neoplasm; D014316:Tritium; D013762:Tetrahydrofolate Dehydrogenase; D003857:Deoxyuridine; D008727:Methotrexate