title: Control of pyrimidine biosynthesis in human lymphocytes. Inhibition of pyrimidine biosynthesis de novo in phytohemagglutinin-stimulated lymphocytes by external uridine and its inhibition mechanism.
mesh_terms: D001221:Aspartate Carbamoyltransferase / Q000378:metabolism; D001224:Aspartic Acid / Q000096:biosynthesis / Q000302:isolation & purification; D001380:Azauridine / Q000494:pharmacology; D001639:Bicarbonates / Q000378:metabolism; D002219:Carbamates / Q000096:biosynthesis / Q000302:isolation & purification; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D006801:Humans; D037102:Lectins / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009696:Nucleic Acids / Q000096:biosynthesis; D010756:Phosphoric Acids / Q000096:biosynthesis; D010770:Phosphotransferases / Q000037:antagonists & inhibitors / Q000378:metabolism; D011743:Pyrimidines / Q000096:biosynthesis*; D014316:Tritium; D014500:Uracil Nucleotides / Q000096:biosynthesis / Q000302:isolation & purification; D014529:Uridine / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D001639:Bicarbonates; D002219:Carbamates; D002247:Carbon Isotopes; D037102:Lectins; D009696:Nucleic Acids; D010756:Phosphoric Acids; D011743:Pyrimidines; D014500:Uracil Nucleotides; D014316:Tritium; D002245:Carbon Dioxide; D001224:Aspartic Acid; D001380:Azauridine; D001221:Aspartate Carbamoyltransferase; D010770:Phosphotransferases; D014529:Uridine