Effect of late night calcium supplements on overnight urinary calcium excretion in premenopausal and postmenopausal women.
The overnight urinary calcium/creatinine ratio is higher in the early years after the menopause than before it. However, the increment of urinary calcium/creatinine after a late evening calcium supplement is less in early postmenopausal than in premenopausal women. It is suggested that calcium therapy in postmenopausal osteoporosis may be best administered as a single late evening dose rather than in divided doses throughout the day.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use / Q000652:urine*; D002136:Calcium, Dietary; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010024:Osteoporosis / Q000188:drug therapy; D013997:Time Factors
D002136:Calcium, Dietary; D003404:Creatinine; D002118:Calcium