A case of chronic granulocytopenia associated with vasculitis and amyloidosis.
A patient is described with chronic neutropenia who was followed for 22 years. She had varying patterns of neutropenia, sometimes cyclical, sometimes almost agranulocytic; at times the counts were normal. The course was complicated by a vasculitis and finally by large vessel thrombosis; extensive amyloid was found in small vessels at necropsy.
D000293:Adolescent; D000328:Adult; D000380:Agranulocytosis / Q000150:complications*; D000686:Amyloidosis / Q000150:complications*; D005260:Female; D005734:Gangrene / Q000150:complications; D006801:Humans; D007958:Leukocyte Count; D009504:Neutrophils; D011655:Pulmonary Embolism / Q000150:complications; D013156:Splenectomy; D013256:Steroids / Q000627:therapeutic use; D013315:Stress, Psychological; D014652:Vascular Diseases / Q000150:complications*
D013256:Steroids