Affinity labeling of steroid binding sites. Study of the active site of 20-beta-hydroxysteroid dehydrogenase with 6-beta- and 11 alpha-bromoacetoxyprogesterone.
D000085:Acetates; D000478:Alkylation; D000596:Amino Acids; D001665:Binding Sites; D001966:Bromine; D002247:Carbon Isotopes; D055598:Chemical Phenomena; D002621:Chemistry; D002713:Chlorine; D003348:Cortisone; D003545:Cysteine; D006908:Hydroxyprogesterones; D006913:Hydroxysteroid Dehydrogenases / Q000037:antagonists & inhibitors; D006914:Hydroxysteroids; D007455:Iodine; D007461:Iodoacetates; D007553:Isotope Labeling; D007700:Kinetics; D008715:Methionine; D008956:Models, Chemical; D011283:Pregnenes / Q000138:chemical synthesis; D013302:Streptomyces / Q000201:enzymology*; D013329:Structure-Activity Relationship; D014316:Tritium
D000085:Acetates; D000596:Amino Acids; D002247:Carbon Isotopes; D006908:Hydroxyprogesterones; D006914:Hydroxysteroids; D007461:Iodoacetates; D011283:Pregnenes; D014316:Tritium; C005669:11 alpha-bromoacetoxyprogesterone; D002713:Chlorine; D007455:Iodine; D008715:Methionine; D006913:Hydroxysteroid Dehydrogenases; D003545:Cysteine; D001966:Bromine; D003348:Cortisone