title: Coma associated with vincristine therapy.
abstract: Three cases of coma after vincristine therapy are described. One patient had hyponatraemia and other features of inappropriate secretion of antidiuretic hormone. The effects were temporary, and full recovery occurred in all three patients.
mesh_terms: D000293:Adolescent; D000368:Aged; D003128:Coma / Q000139:chemically induced* / Q000150:complications; D004569:Electroencephalography; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D007010:Hyponatremia / Q000150:complications / Q000209:etiology; D007938:Leukemia / Q000188:drug therapy; D008199:Lymphadenitis / Q000188:drug therapy; D008297:Male; D014667:Vasopressins / Q000378:metabolism; D014750:Vincristine / Q000009:adverse effects*
chemical_list: D014667:Vasopressins; D014750:Vincristine