Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo.
D000082:Acetaminophen; D000818:Animals; D002250:Carbon Radioisotopes; D002467:Cell Nucleus / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003035:Cobalt / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology / Q000378:metabolism; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008862:Microsomes, Liver / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D009336:Necrosis / Q000139:chemically induced / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D010882:Piperonyl Butoxide / Q000494:pharmacology; D011485:Protein Binding / Q000187:drug effects; D013997:Time Factors; D014316:Tritium
D002250:Carbon Radioisotopes; D014316:Tritium; D000082:Acetaminophen; D003035:Cobalt; D010882:Piperonyl Butoxide; D010634:Phenobarbital