A general method for modifying the 2-methyl group of pyridoxol. Synthesis and biological activity of 2-vinyl- and 2-ethynylpyridoxols and related compounds.
D000080:Acetals / Q000138:chemical synthesis / Q000627:therapeutic use; D000480:Alkynes / Q000138:chemical synthesis / Q000627:therapeutic use; D000818:Animals; D002277:Carcinoma / Q000188:drug therapy; D002478:Cells, Cultured; D005260:Female; D066298:In Vitro Techniques; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy; D051379:Mice; D011736:Pyridoxine / Q000138:chemical synthesis* / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D014753:Vinyl Compounds / Q000138:chemical synthesis / Q000627:therapeutic use
D000080:Acetals; D000480:Alkynes; D014753:Vinyl Compounds; D011736:Pyridoxine