Synthesis and biological evaluation of poly-gamma-glutamyl derivatives of methotrexate.
D000818:Animals; D001681:Biological Assay; D002250:Carbon Radioisotopes; D002848:Chromatography, DEAE-Cellulose; D002852:Chromatography, Ion Exchange; D004355:Drug Stability; D005459:Fluorides; D005971:Glutamates; D006867:Hydrolases; D007668:Kidney / Q000201:enzymology; D008727:Methotrexate / Q000138:chemical synthesis* / Q000494:pharmacology; D010455:Peptides / Q000138:chemical synthesis* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D013291:Streptococcus / Q000187:drug effects; D013329:Structure-Activity Relationship; D013552:Swine
D002250:Carbon Radioisotopes; D005971:Glutamates; D010455:Peptides; D006867:Hydrolases; D005459:Fluorides; D008727:Methotrexate