Metabolism of N,2-dimethyl-2-phenylsuccinimide (methsuximide) by the epoxide-diol pathway in rat, guinea pig and human.
D000818:Animals; D000927:Anticonvulsants / Q000378:metabolism*; D002675:Child, Preschool; D002849:Chromatography, Gas; D004988:Ethers, Cyclic / Q000378:metabolism*; D005965:Glucuronates / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D006900:Hydroxylation; D008297:Male; D013058:Mass Spectrometry; D008745:Methylation; D010672:Phenytoin / Q000627:therapeutic use; D011324:Primidone / Q000627:therapeutic use; D051381:Rats; D013045:Species Specificity; D013388:Succinimides / Q000378:metabolism* / Q000627:therapeutic use
D000927:Anticonvulsants; D004988:Ethers, Cyclic; D005965:Glucuronates; D013388:Succinimides; D011324:Primidone; D010672:Phenytoin