Use of fetal cell culture as an experimental system for predicting drug metabolism in the intact animal.
D000818:Animals; D001580:Benzopyrenes / Q000494:pharmacology; D002478:Cells, Cultured; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D005333:Fetus; D006838:Hydrocarbons; D008099:Liver / Q000201:enzymology; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D006899:Mixed Function Oxygenases / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy; D013997:Time Factors
D001580:Benzopyrenes; D006838:Hydrocarbons; D004364:Pharmaceutical Preparations; D008748:Methylcholanthrene; D006899:Mixed Function Oxygenases