Insulin degradation. VII. Sequential degradation of insulin by rat liver homogenates at physiologic concentrations of insulin and in the absence of exogenous glutathione.
D000818:Animals; D002850:Chromatography, Gel; D003956:Dialysis; D004220:Disulfides; D010450:Endopeptidases / Q000378:metabolism; D005978:Glutathione / Q000494:pharmacology*; D005980:Glutathione Reductase / Q000378:metabolism; D007328:Insulin / Q000378:metabolism*; D007457:Iodine Radioisotopes; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D010446:Peptide Fragments; D051381:Rats; D013997:Time Factors
D004220:Disulfides; D007328:Insulin; D007457:Iodine Radioisotopes; D010446:Peptide Fragments; D005980:Glutathione Reductase; D010450:Endopeptidases; D005978:Glutathione