Prasinons A and B: potent insecticides from Streptomyces prasinus.
Two metabolites which have high activity against sheep blowfly larvae (Lucilia sericata and L. cuprina) were found to be produced by Streptomyces prasinus NCIB 10719. These substances were isolated from culture filtrate by solvent extraction and chromatography and named prasinons A and B. Fermentation factors affecting the formation of these substances are described together with their physical, chemical, and biological properties.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D003470:Culture Media; D004175:Diptera / Q000187:drug effects; D005285:Fermentation; D005612:Freeze Drying; D007306:Insecticides / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D000432:Methanol; D008826:Microbial Sensitivity Tests; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*; D013395:Sucrose / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003470:Culture Media; D007306:Insecticides; D013395:Sucrose; D000432:Methanol