Tolerance phenomena with neuroleptics catalepsy, apomorphine stereotypies and striatal dopamine metabolism in the rat after single and repeated administration of loxapine and haloperidol.
D000818:Animals; D001058:Apomorphine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D001479:Basal Ganglia / Q000378:metabolism*; D002375:Catalepsy / Q000139:chemically induced*; D003342:Corpus Striatum / Q000378:metabolism; D003989:Dibenzoxazepines / Q000008:administration & dosage / Q000494:pharmacology*; D004298:Dopamine / Q000032:analysis / Q000378:metabolism*; D004361:Drug Tolerance; D006220:Haloperidol / Q000008:administration & dosage / Q000494:pharmacology*; D006719:Homovanillic Acid / Q000378:metabolism; D006801:Humans; D008297:Male; D010879:Piperazines / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects; D013997:Time Factors; D014149:Tranquilizing Agents / Q000008:administration & dosage / Q000494:pharmacology*
D003989:Dibenzoxazepines; D010879:Piperazines; D014149:Tranquilizing Agents; D006220:Haloperidol; D001058:Apomorphine; D004298:Dopamine; D006719:Homovanillic Acid