Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.
D000082:Acetaminophen / Q000378:metabolism*; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D003035:Cobalt / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D007668:Kidney / Q000473:pathology; D007928:Lethal Dose 50; D008099:Liver / Q000473:pathology; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D008815:Mice, Inbred Strains; D009336:Necrosis / Q000139:chemically induced; D010634:Phenobarbital / Q000494:pharmacology; D010882:Piperonyl Butoxide / Q000494:pharmacology; D051381:Rats; D013045:Species Specificity; D013997:Time Factors; D014316:Tritium
D014316:Tritium; D000082:Acetaminophen; D003035:Cobalt; D008748:Methylcholanthrene; D010882:Piperonyl Butoxide; D010634:Phenobarbital