title: Retinyl acetate: effect on cellular content of RNA in epidermis in cell culture in chemically defined medium.
abstract: Cell cultures of epidermis from newborn mice were established in chemically defined medium. Additions of retinyl acetate to these cultures caused a significant increase in cellular RNA content. Addition of insulin and hydrocortisone to the cultures potentiated the effect of retinyl acetate on cellular RNA content.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004357:Drug Synergism; D006854:Hydrocortisone / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis*; D012867:Skin / Q000378:metabolism*; D014801:Vitamin A / Q000494:pharmacology*
chemical_list: D007328:Insulin; D014801:Vitamin A; D012313:RNA; D004247:DNA; D006854:Hydrocortisone