Reduction of alpha-oxo carboxylic acids by pigeon liver 'malic' enzyme.
1. Pigeon liver ;malic' enzyme [l-malate-NADP(+) oxidoreductase (decarboxylating); EC 1.1.1.40] was shown to catalyse the reductase reaction: [Formula: see text] l-Malate was identified as the reaction product, and was formed in stoicheiometric amount. 2. In addition to oxaloacetate and pyruvate, a number of other alpha-oxo carboxylic acids were also reduced.
D000818:Animals; D002384:Catalysis; D010856:Columbidae; D007651:Keto Acids / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008274:Magnesium; D008291:Malate Dehydrogenase; D008293:Malates / Q000378:metabolism; D008345:Manganese; D010071:Oxaloacetates / Q000378:metabolism
D007651:Keto Acids; D008293:Malates; D010071:Oxaloacetates; D008345:Manganese; D008291:Malate Dehydrogenase; D008274:Magnesium