Amphotericin pharmacophobia.
Five cases are described in which fear of the possibly hazardous effects of giving amphotericin to patients with kidney disease resulted in death from progressive infection by an amphotericin-sensitive fungus (Cryptococcus neoformans in three cases, Blastomyces dermatitidis in one case, and Histoplasma capsulatum in one case).
D000309:Adrenal Insufficiency / Q000209:etiology; D000328:Adult; D000666:Amphotericin B / Q000009:adverse effects*; D001291:Attitude of Health Personnel; D001759:Blastomycosis / Q000188:drug therapy; D003453:Cryptococcosis / Q000150:complications / Q000188:drug therapy; D003655:Decerebrate State / Q000209:etiology; D011307:Drug Prescriptions; D005260:Female; D006660:Histoplasmosis / Q000150:complications / Q000188:drug therapy; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000150:complications; D008172:Lung Diseases, Fungal / Q000150:complications; D008297:Male; D008508:Medication Errors; D008581:Meningitis / Q000209:etiology; D008590:Meningoencephalitis / Q000150:complications; D009181:Mycoses / Q000188:drug therapy*; D010698:Phobic Disorders; D012507:Sarcoidosis / Q000150:complications; D013122:Spinal Diseases / Q000209:etiology
D000666:Amphotericin B