title: Chromosome markers in Mus musculus: strain differences in C-banding.
abstract: The mitotic chromosomes of several inbred strains of mice and a series of F(1) hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F(1) hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000032:analysis*; D004622:Embryo, Mammalian; D005260:Female; D008040:Genetic Linkage; D006570:Heterochromatin / Q000032:analysis; D006720:Homozygote; D006824:Hybridization, Genetic; D007621:Karyotyping; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008856:Microscopy, Fluorescence; D009150:Mustard Compounds; D011110:Polymorphism, Genetic; D011796:Quinacrine; D013045:Species Specificity
chemical_list: D006570:Heterochromatin; D009150:Mustard Compounds; D011796:Quinacrine