The influence of renal function on plasma levels, urinary excretion, metabolism, and antihypertensive effect of guanethidine (ismelin) in man.
D000328:Adult; D000959:Antihypertensive Agents / Q000378:metabolism; D001773:Blood Cells / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D003404:Creatinine / Q000097:blood; D004305:Dose-Response Relationship, Drug; D005260:Female; D006145:Guanethidine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology / Q000627:therapeutic use / Q000652:urine; D006146:Guanidines / Q000652:urine; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D007275:Injections, Intravenous; D007668:Kidney / Q000503:physiopathology*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000652:urine; D014316:Tritium
D000959:Antihypertensive Agents; D006146:Guanidines; D010087:Oxides; D014316:Tritium; D003404:Creatinine; D006145:Guanethidine