Microbiological transformation of steroids. 1-Dehydrogenation of 17,21-dihydroxypregn-4-ene-3,20-dione with Glomerella cingulata.
The micro-organism Glomerella cingulata dehydrogenates 17,21-dihydroxypregn-4-ene-3,20-dione to 17,21-dihydroxypregna-1,4-diene-3,20-dione in high yield practically without by-products.
D001203:Ascomycota / Q000378:metabolism*; D002845:Chromatography; D003345:Corticosterone / Q000378:metabolism*; D009904:Optical Rotation; D011276:Pregnanediol / Q000096:biosynthesis; D013053:Spectrophotometry
D011276:Pregnanediol; D003345:Corticosterone