Mode of action of the macrolide-type antibiotic, chlorothricin. Kinetic study of the inhibition of pyruvate carboxylase from Bacillus stearothermophilus.
D000105:Acetyl Coenzyme A; D000255:Adenosine Triphosphate; D000494:Allosteric Regulation; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects / Q000201:enzymology*; D001665:Binding Sites; D004789:Enzyme Activation; D006027:Glycosides / Q000494:pharmacology*; D007700:Kinetics; D007783:Lactones / Q000494:pharmacology; D008274:Magnesium; D008433:Mathematics; D008956:Models, Chemical; D011485:Protein Binding; D011766:Pyruvate Carboxylase / Q000037:antagonists & inhibitors*; D011773:Pyruvates; D012044:Regression Analysis; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D006027:Glycosides; D007783:Lactones; D011773:Pyruvates; D000105:Acetyl Coenzyme A; D000255:Adenosine Triphosphate; D011766:Pyruvate Carboxylase; D008274:Magnesium