The amino acid sequence around the reactive cysteine residue in human plasma Factor XII.
1. Activated human plasma factor XIII was 65% inhibited by iodo[(14)C]acetate and incorporated 0.6 mol of label into the alpha subunit, which eventually was allowed to form a precipitate. 2. All the label was recovered as S-carboxymethylcysteine in a tetra-peptide of sequence Gly-Gln-Cys-Trp.
D000595:Amino Acid Sequence; D001345:Autoradiography; D002250:Carbon Radioisotopes; D002850:Chromatography, Gel; D003545:Cysteine; D004590:Electrophoresis, Paper; D005176:Factor XIII / Q000032:analysis* / Q000037:antagonists & inhibitors; D006801:Humans; D007461:Iodoacetates
D002250:Carbon Radioisotopes; D007461:Iodoacetates; D005176:Factor XIII; D003545:Cysteine