title: Regulation of de novo purine synthesis in the Lesch-Nyhan syndrome.
mesh_terms: D000225:Adenine / Q000096:biosynthesis* / Q000494:pharmacology; D000328:Adult; D000641:Ammonia / Q000378:metabolism; D002250:Carbon Radioisotopes; D002474:Cell-Free System; D002478:Cells, Cultured; D002675:Child, Preschool; D005260:Female; D005973:Glutamine / Q000378:metabolism; D006147:Guanine; D006801:Humans; D007042:Hypoxanthines / Q000096:biosynthesis* / Q000494:pharmacology; D007926:Lesch-Nyhan Syndrome / Q000378:metabolism*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010428:Pentosephosphates / Q000378:metabolism; D010430:Pentosyltransferases / Q000378:metabolism; D000637:Transaminases / Q000097:blood
chemical_list: D002250:Carbon Radioisotopes; D007042:Hypoxanthines; D010428:Pentosephosphates; D005973:Glutamine; D006147:Guanine; D000641:Ammonia; D010430:Pentosyltransferases; D000637:Transaminases; D000225:Adenine