Mutations and loss of transforming activity of DNA caused by the O-glucuronide conjugate of the carcinogen, N-hydroxy-2-aminofluorene.
D002273:Carcinogens / Q000494:pharmacology; D002499:Centrifugation, Density Gradient; D004247:DNA; D004269:DNA, Bacterial; D005449:Fluorenes / Q000494:pharmacology*; D008040:Genetic Linkage; D005965:Glucuronates / Q000494:pharmacology*; D009153:Mutagens; D009154:Mutation; D009876:Operon; D014170:Transformation, Genetic / Q000187:drug effects*; D014364:Tryptophan / Q000096:biosynthesis
D002273:Carcinogens; D004269:DNA, Bacterial; D005449:Fluorenes; D005965:Glucuronates; D009153:Mutagens; D014364:Tryptophan; D004247:DNA