In vitro effect of virazole against influenza viruses.
The minimal inhibitory concentrations of Virazole against 32 mean tissue culture infective doses of three type A influenza strains including type A/England/42/72 (H3N2) and a type B strain in tissue culture were 0.1 and 0.05 mug/ml, respectively. The growth inhibition pattern by various Virazole concentrations of type A virus was similar to that of the type B virus. Virazole appears to be slightly more potent against the A/England/42/72 strain than are other antiinfluenzal agents.
D000577:Amides / Q000494:pharmacology; D000998:Antiviral Agents / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009975:Orthomyxoviridae / Q000187:drug effects*; D012263:Ribonucleosides / Q000494:pharmacology*; D014230:Triazoles / Q000494:pharmacology
D000577:Amides; D000998:Antiviral Agents; D012263:Ribonucleosides; D014230:Triazoles