title: An explanation of the asymmetric binding of sugars to the human erythrocyte sugar-transport systems.
abstract: 6-O-Alkyl-d-galactoses competitively inhibit the erythrocyte sugar-transport system when added to the outside of the cells, but not to the inside. n-Propyl beta-d-glucopyranoside competitively inhibits the system on the inside of the cells, but not on the outside. A model for sugar transport is proposed.
mesh_terms: D000433:1-Propanol / Q000494:pharmacology; D001665:Binding Sites; D001693:Biological Transport, Active / Q000187:drug effects; D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000097:blood; D002462:Cell Membrane / Q000378:metabolism; D003864:Depression, Chemical; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005690:Galactose / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism; D006027:Glycosides / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D008954:Models, Biological; D013013:Sorbose / Q000378:metabolism
chemical_list: D002241:Carbohydrates; D006027:Glycosides; D000433:1-Propanol; D005947:Glucose; D013013:Sorbose; D005690:Galactose