title: Effect of physicochemical and pharmacokinetic properties of barbiturates on the induction of drug metabolism.
mesh_terms: D000654:Amobarbital / Q000494:pharmacology; D000814:Aniline Compounds; D000818:Animals; D001463:Barbiturates / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D006207:Half-Life; D006591:Hexobarbital / Q000494:pharmacology; D007700:Kinetics; D008055:Lipids; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D010088:Oxidoreductases / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011506:Proteins / Q000378:metabolism; D051381:Rats; D012631:Secobarbital / Q000494:pharmacology; D012995:Solubility
chemical_list: D000814:Aniline Compounds; D001463:Barbiturates; D008055:Lipids; D004364:Pharmaceutical Preparations; D011506:Proteins; D012631:Secobarbital; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D010088:Oxidoreductases; D010089:Oxidoreductases, N-Demethylating; D000654:Amobarbital; D010634:Phenobarbital