The mechanism of the alpha-chymotrypsin and trypsin-catalyzed hydrolysis of amides. Evidence for the participation of the active serine in the amidase activity of trypsin.
D000577:Amides / Q000378:metabolism*; D000581:Amidohydrolases / Q000378:metabolism*; D000813:Anilides / Q000378:metabolism; D002918:Chymotrypsin / Q000378:metabolism*; D004950:Esterases / Q000378:metabolism; D004952:Esters / Q000378:metabolism; D006868:Hydrolysis; D007700:Kinetics; D012694:Serine / Q000378:metabolism*; D013329:Structure-Activity Relationship; D014357:Trypsin / Q000378:metabolism*
D000577:Amides; D000813:Anilides; D004952:Esters; D012694:Serine; D004950:Esterases; D002918:Chymotrypsin; D014357:Trypsin; D000581:Amidohydrolases