The blockade of the local generation of prostaglandins explains the analgesic action of aspirin.
D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D003864:Depression, Chemical; D004285:Dogs; D011453:Prostaglandins / Q000096:biosynthesis*
D000700:Analgesics; D011453:Prostaglandins; D001241:Aspirin