Dissemination of influenza virus between anatomically isolated sites in ferrets.
Influenza virus was shown to disseminate from the respiratory tract of nasally infected ferrets to a surgically formed, subcutaneous tracheal pouch. Conversely, ferrets infected via the pouch shed virus from the upper respiratory tract. These events occurred within the first 24 h after infection. Passively administered ferret antibody to virus did not prevent the dissemination.
D000818:Animals; D002335:Carnivora; D002645:Chickens; D004912:Erythrocytes / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D008297:Male; D009297:Nasal Mucosa / Q000378:metabolism; D009666:Nose / Q000276:immunology / Q000382:microbiology*; D009975:Orthomyxoviridae / Q000276:immunology*; D013997:Time Factors; D014132:Trachea / Q000276:immunology / Q000382:microbiology*