title: Effect of an exotoxin from Bacillus thuringiensis on deoxyribonucleic acid-dependent ribonucleic acid polymerase in nuclei from adult Sarcophaga bullata. Unusual behaviour of eukaryotic polymerases to inhibitors.
abstract: The DNA-dependent RNA polymerase activities in nuclei isolated from adult Sarcophaga bullata are unusual in their responses to metal ions, ionic strength and inhibitors. There is an activity that is sensitive both to rifamycin and to alpha-amanitin. The activity is less sensitive to Bacillus thuringiensis exotoxin than is larval polymerase, and low concentration of exotoxin provoke a slight stimulation.
mesh_terms: D000645:Ammonium Sulfate / Q000494:pharmacology; D000818:Animals; D001407:Bacillus; D001487:Basidiomycota; D002467:Cell Nucleus / Q000201:enzymology*; D004247:DNA; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007814:Larva / Q000201:enzymology; D008670:Metals / Q000494:pharmacology; D009183:Mycotoxins / Q000494:pharmacology; D009842:Oligopeptides / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000494:pharmacology; D012294:Rifamycins / Q000494:pharmacology; D013997:Time Factors; D014118:Toxins, Biological / Q000494:pharmacology*
chemical_list: D008670:Metals; D009183:Mycotoxins; D009842:Oligopeptides; D010456:Peptides, Cyclic; D012294:Rifamycins; D014118:Toxins, Biological; D004247:DNA; D012321:DNA-Directed RNA Polymerases; D000645:Ammonium Sulfate