Influence of pyridine and some pyridine derivatives on spectral properties of reduced microsomes and on microsomal drug metabolizing activity.
D000633:Aminopyrine N-Demethylase / Q000037:antagonists & inhibitors; D000814:Aniline Compounds; D000818:Animals; D000840:Anisoles; D002248:Carbon Monoxide / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D003067:Coenzymes / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008024:Ligands; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008797:Metyrapone / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet
D000814:Aniline Compounds; D000840:Anisoles; D003067:Coenzymes; D008024:Ligands; D004364:Pharmaceutical Preparations; D011725:Pyridines; D008748:Methylcholanthrene; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D000633:Aminopyrine N-Demethylase; D010634:Phenobarbital; D008797:Metyrapone