title: Effects of metyrapone on pregnenolone biosynthesis and on cholesterol-cytochrome P-450 interaction in the adrenal.
mesh_terms: D000311:Adrenal Glands / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D002250:Carbon Radioisotopes; D002784:Cholesterol / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006908:Hydroxyprogesterones / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D008797:Metyrapone / Q000494:pharmacology*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D011284:Pregnenolone / Q000096:biosynthesis*; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D013057:Spectrum Analysis; D013997:Time Factors; D014316:Tritium
chemical_list: D002250:Carbon Radioisotopes; D006908:Hydroxyprogesterones; D014316:Tritium; D011374:Progesterone; D011284:Pregnenolone; D003577:Cytochrome P-450 Enzyme System; D002784:Cholesterol; D008797:Metyrapone