Active site of trypsin-like enzyme from Streptomyces erythreus. Specific inactivation by new chloromethyl ketones derived from Na-dinitrophenyl-L-lysine and Na-tosyl-L-arginine.
D000818:Animals; D001120:Arginine; D001665:Binding Sites; D002417:Cattle; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D010450:Endopeptidases / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D007659:Ketones / Q000494:pharmacology*; D007700:Kinetics; D008239:Lysine; D009578:Nitrobenzenes; D010179:Pancreas / Q000201:enzymology; D011480:Protease Inhibitors; D011485:Protein Binding; D013045:Species Specificity; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces / Q000187:drug effects / Q000201:enzymology*; D014105:Tosyl Compounds; D014361:Trypsin Inhibitors
D007659:Ketones; D009578:Nitrobenzenes; D011480:Protease Inhibitors; D014105:Tosyl Compounds; D014361:Trypsin Inhibitors; D001120:Arginine; D010450:Endopeptidases; D008239:Lysine