Model studies of the thymidylate synthetase reaction. Nucleophilic displacement of 5-p-nitrophenoxymethyluracils.
D000588:Amines; D055598:Chemical Phenomena; D002621:Chemistry; D003201:Computers; D003903:Deuterium; D004789:Enzyme Activation; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007553:Isotope Labeling; D007700:Kinetics; D008433:Mathematics; D008780:Methyltransferases / Q000378:metabolism*; D008956:Models, Chemical; D009574:Nitro Compounds / Q000378:metabolism; D009862:Online Systems; D010647:Phenyl Ethers / Q000378:metabolism*; D013763:Tetrahydrofolates / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D013940:Thymidylate Synthase / Q000378:metabolism; D013941:Thymine / Q000378:metabolism*
D000588:Amines; D009574:Nitro Compounds; D010647:Phenyl Ethers; D013763:Tetrahydrofolates; D003903:Deuterium; D008780:Methyltransferases; D013940:Thymidylate Synthase; D013941:Thymine; D013936:Thymidine