title: Leucocyte migration studies in Crohn's disease using Crohn's colon homogenate and mitochondrial and microsomal fractions.
abstract: Leucocytes from 38 patients with Crohn's disease were tested for evidence of migration inhibition in the presence of preparations of colon from a patient with this disease. The occurrence of migration inhibition showed a positive correlation with clinically active disease and a negative correlation with immunosuppressive treatment. It was not seen with leucocytes from 12 healthy subjects.
mesh_terms: D000328:Adult; D002464:Cell Migration Inhibition; D003106:Colon / Q000276:immunology; D003424:Crohn Disease / Q000276:immunology*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D008861:Microsomes / Q000276:immunology; D008928:Mitochondria / Q000276:immunology