Role of menaquinone in nitrate respiration in Staphylococcus aureus.
Two menaquinone-deficient and one aromatic-deficient mutants of Staphylococcus aureus were unable to reduce nitrate to nitrite. Reinitiation of menaquinone synthesis in the aromatic-deficient mutant by growing it with shikimic acid restored its nitrate respiratory activity. The results clearly demonstrate a role for menaquinone in nitrate respiration in Staphylococcus aureus.
D000693:Anaerobiosis; D004579:Electron Transport; D009154:Mutation; D009566:Nitrates / Q000378:metabolism*; D009573:Nitrites / Q000096:biosynthesis; D010084:Oxidation-Reduction; D012765:Shikimic Acid / Q000378:metabolism; D013053:Spectrophotometry; D013210:Staphylococcus / Q000378:metabolism*; D014812:Vitamin K / Q000096:biosynthesis / Q000494:pharmacology*
D009566:Nitrates; D009573:Nitrites; D014812:Vitamin K; D012765:Shikimic Acid