Inhibition of gluconeogenesis and of cell respiration by 1-methyl-4(3-methyl-5-isoxazolyl-)pyridinium chloride in the perfused guinea pig liver.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001645:Biguanides / Q000494:pharmacology; D002245:Carbon Dioxide / Q000378:metabolism; D002849:Chromatography, Gas; D005636:Fructosephosphates / Q000378:metabolism; D005943:Gluconeogenesis / Q000187:drug effects*; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008293:Malates / Q000378:metabolism; D008297:Male; D010080:Oxazoles / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects*; D010477:Perfusion; D011726:Pyridinium Compounds / Q000494:pharmacology*; D013696:Temperature
D001645:Biguanides; D005636:Fructosephosphates; D008293:Malates; D010080:Oxazoles; D011726:Pyridinium Compounds; D002245:Carbon Dioxide; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate