Differential effects of benzodioxane, chroman, and dihydrobenzofuran analogs of clofibrate on various parameters of hepatic drug metabolism.
D000814:Aniline Compounds; D000818:Animals; D001572:Benzofurans / Q000494:pharmacology*; D001578:Benzopyrans / Q000494:pharmacology*; D001835:Body Weight / Q000187:drug effects; D002994:Clofibrate / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004147:Dioxins / Q000494:pharmacology*; D004790:Enzyme Induction / Q000187:drug effects; D000960:Hypolipidemic Agents / Q000494:pharmacology; D008099:Liver / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000032:analysis / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009019:Morphinans; D009929:Organ Size; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011506:Proteins / Q000032:analysis; D051381:Rats; D013329:Structure-Activity Relationship
D000814:Aniline Compounds; D001572:Benzofurans; D001578:Benzopyrans; D004147:Dioxins; D000960:Hypolipidemic Agents; D009019:Morphinans; D004364:Pharmaceutical Preparations; D011506:Proteins; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010089:Oxidoreductases, N-Demethylating; D002994:Clofibrate; D010634:Phenobarbital