title: The molecular form of acetylcholinesterase as determined by irradiation inactivation.
abstract: The molecular size of acetylcholinesterase (EC 3.1.1.7) from the electric organ of Electrophorus electricus and erythrocyte ;ghosts' was estimated in both membrane-bound and purified preparations by irradiation inactivation. Results suggest that the form of the enzyme in the membrane is a monomer of molecular weight approx. 75000 and that multiple forms of the enzyme observed in solubilized preparations are aggregates of this monomer.
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood / Q000528:radiation effects*; D000818:Animals; D001188:Artiodactyla; D001665:Binding Sites; D002417:Cattle; D002462:Cell Membrane / Q000201:enzymology; D004307:Dose-Response Relationship, Radiation; D004557:Electric Organ / Q000166:cytology / Q000201:enzymology; D004593:Electrophorus; D004912:Erythrocytes / Q000166:cytology / Q000201:enzymology; D006801:Humans; D046911:Macromolecular Substances; D008970:Molecular Weight; D009928:Organ Specificity; D011485:Protein Binding; D011487:Protein Conformation; D011830:Radiation Effects; D012995:Solubility; D013045:Species Specificity
chemical_list: D046911:Macromolecular Substances; D000110:Acetylcholinesterase