Prostaglandins stimulate thyroid function in pregnant women.
Intravaginal or intravenous administration of prostaglandin F(2alpha) to pregnant women produced significant elevations of plasma triiodothyronine and thyroxine concentrations, but no rise of thyrotropin. These observations are consistent with those of previous in vitro studies indicating that prostaglandins can act directly on the thyroid gland to stimulate thyroid hormone synthesis or release, or both.
D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D011247:Pregnancy; D011453:Prostaglandins / Q000008:administration & dosage / Q000494:pharmacology*; D011863:Radioimmunoassay; D013268:Stimulation, Chemical; D013488:Suppositories; D013961:Thyroid Gland / Q000187:drug effects* / Q000378:metabolism; D013963:Thyroid Hormones / Q000378:metabolism; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood; D014621:Vagina
D011453:Prostaglandins; D013488:Suppositories; D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine