title: Miniature end plate potentials recorded from mammalian myoneural junction in vivo.
abstract: Fibers of the cat soleus muscle had a mean resting potential of 87 millivolts as measured with an intracellular microelectrode. Miniature end plate potentials had a mean amplitude of 0.95 millivolt, a mean frequency of 1.01 per second, a mean duration of 4.44 milliseconds, and a mean rate of rise of 0.99 volt per second. Two populations of response could be discerned on the basis of rate of rise. Neither alpha-chloralose nor nerve section had any significant effect on the response pattern. The in vivo preparation appears to provide a superior representation of the physiology of the myoneural junction.
mesh_terms: D000758:Anesthesia; D000818:Animals; D002415:Cats; D002698:Chloralose; D003714:Denervation; D008564:Membrane Potentials; D008839:Microelectrodes; D009469:Neuromuscular Junction / Q000502:physiology*; D013116:Spinal Cord
chemical_list: D002698:Chloralose