title: Fecal bacterial beta-glucuronidase: control by diet.
abstract: The effect of a mixed Western, high meat diet or a nonmeat diet on the intestinal bacterial beta-glucuronidase activity was studied in human volunteers. This enzyme was significantly higher in stools of subjects on a high meat diet as compared to the nonmeat regimen. Thus, intestinal flora of subjects on a high meat diet was more able to hydrolyze glucuronide conjugates than that of individuals on a nonmeat diet. This, in turn, may raise the amount of substances, such as carcinogens, within the colonic lumen.
mesh_terms: D000328:Adult; D000818:Animals; D001419:Bacteria / Q000201:enzymology*; D002417:Cattle; D002645:Chickens; D004032:Diet; D005243:Feces / Q000201:enzymology / Q000382:microbiology*; D005260:Female; D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D008297:Male; D008460:Meat; D008875:Middle Aged; D013552:Swine
chemical_list: D005966:Glucuronidase