The topographical differences in the active site region of alpha-chymotrypsin, subtilisin Novo, and subtilisin Carlsberg. Mapping the aromatic binding site by inhibitors (virtual substrates).
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001593:Benzyl Compounds; D001665:Binding Sites; D001667:Binding, Competitive; D055598:Chemical Phenomena; D002621:Chemistry; D002918:Chymotrypsin / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005561:Formates; D006863:Hydrogen-Ion Concentration; D007536:Isomerism; D007700:Kinetics; D008433:Mathematics; D008956:Models, Chemical; D009842:Oligopeptides / Q000378:metabolism; D010649:Phenylalanine; D013329:Structure-Activity Relationship; D013381:Subtilisins / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013816:Thermodynamics; D014961:X-Ray Diffraction
D000596:Amino Acids; D001593:Benzyl Compounds; D005561:Formates; D009842:Oligopeptides; D010649:Phenylalanine; D013381:Subtilisins; D002918:Chymotrypsin