title: Brain hyaluronidase: changes in activity during chick development.
abstract: Development of embryonic chick brain is characterized by high levels of hyaluronidase activity and of hyaluronate, both of which decrease rapidly soon after the chick hatches. By analogy to other systems, it is proposed that the sequence of hyaluronate production and its enzymatic removal may have a developmental role in brain formation.
mesh_terms: D000818:Animals; D001921:Brain / Q000196:embryology / Q000201:enzymology* / Q000254:growth & development; D001923:Brain Chemistry; D002642:Chick Embryo; D002645:Chickens; D006820:Hyaluronic Acid / Q000032:analysis; D006821:Hyaluronoglucosaminidase / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007700:Kinetics; D009419:Nerve Tissue Proteins / Q000032:analysis
chemical_list: D009419:Nerve Tissue Proteins; D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase