In vitro repair of UV-irradiated Micrococcus luteus bacteriophage N1 transfecting DNA.
Calcium-treated UV-sensitive, host cell reactivation(-) strains of Micrococcus luteus are infected with UV-irradiated N1 DNA. In strains lacking UV endonuclease, in vitro treatment of the irradiated DNA results in transfection enhancement.
D001435:Bacteriophages / Q000254:growth & development / Q000378:metabolism* / Q000528:radiation effects; D002118:Calcium / Q000494:pharmacology; D004260:DNA Repair; D004279:DNA, Viral / Q000528:radiation effects*; D004720:Endonucleases / Q000096:biosynthesis; D008837:Micrococcus / Q000187:drug effects / Q000201:enzymology; D009153:Mutagens; D009154:Mutation; D009604:Nitrosoguanidines; D011830:Radiation Effects; D014170:Transformation, Genetic; D014466:Ultraviolet Rays
D004279:DNA, Viral; D009153:Mutagens; D009604:Nitrosoguanidines; D004720:Endonucleases; D002118:Calcium