Method for the synthesis of the skeletal seeking agent 1-hydroxy-ethylidene-1,1-disodium phosphonate (HEDSPA) and its subsequent labelling with 99mTc.
D000818:Animals; D001847:Bone Diseases / Q000175:diagnosis*; D001842:Bone and Bones / Q000378:metabolism; D000431:Ethanol / Q000138:chemical synthesis; D006801:Humans; D007553:Isotope Labeling; D063065:Organophosphonates / Q000138:chemical synthesis / Q000378:metabolism; D009943:Organophosphorus Compounds / Q000138:chemical synthesis*; D011817:Rabbits; D011877:Radionuclide Imaging; D013667:Technetium
D063065:Organophosphonates; D009943:Organophosphorus Compounds; D000431:Ethanol; D013667:Technetium