Regeneration electrode units: implants for recording from single peripheral nerve fibers in freely moving animals.
Implantable electrode assemblies that become penetrated by regenerating axons were used to record signals from single sensory and motor nerve fibers associated with leg movement in unrestrained amphibians (Xenopus laevis). Such neuroimplants may provide a means for establishing the roles of various muscle afferents and efferents in posture and locomotion, and have potential clinical applications.
D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000502:physiology; D004567:Electrodes, Implanted; D005121:Extremities / Q000294:innervation; D008465:Mechanoreceptors / Q000502:physiology*; D008854:Microscopy, Electron; D009043:Motor Activity; D009046:Motor Neurons / Q000502:physiology*; D009132:Muscles / Q000294:innervation; D009416:Nerve Regeneration; D009474:Neurons / Q000166:cytology; D009475:Neurons, Afferent / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology; D014981:Xenopus