Lectin binding saccharides on a parasitic protozoan.
Leishmania donovani promastigotes were specifically agglutinated by concanavalin A and phytohemagglutinin P. Somatic-somatic, flagellar-somatic, and flagellar-flagellar type agglutination was observed with the lectins. Enzyme-treated promastigotes gave reduced lectin agglutination reactions. The results suggest that complex saccharide moieties are randomly distributed on the surface of this organism.
D000371:Agglutination / Q000187:drug effects; D000681:Amylases / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D002462:Cell Membrane / Q000378:metabolism; D003208:Concanavalin A / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000494:pharmacology; D003910:Dextranase / Q000494:pharmacology; D005688:Galactosamine / Q000494:pharmacology; D037102:Lectins / Q000494:pharmacology*; D007891:Leishmania / Q000378:metabolism*; D011955:Receptors, Drug; D013395:Sucrose / Q000494:pharmacology; D014357:Trypsin / Q000494:pharmacology
D037102:Lectins; D011955:Receptors, Drug; D003208:Concanavalin A; D013395:Sucrose; D005688:Galactosamine; D000681:Amylases; D003910:Dextranase; D014357:Trypsin