title: Stabilization by PRPP  of cellular purine phosphoribosyltransferases against inactivation by freezing and thawing. Study of normal and hypoxanthine-guanine phosphoribosyltransferase deficient human fibroblasts.
mesh_terms: D000225:Adenine; D000818:Animals; D002417:Cattle; D004355:Drug Stability; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology; D005615:Freezing; D006073:Gout / Q000201:enzymology; D006150:Guanine Nucleotides; D006801:Humans; D007292:Inosine Nucleotides; D007926:Lesch-Nyhan Syndrome / Q000201:enzymology; D010428:Pentosephosphates / Q000494:pharmacology*; D010430:Pentosyltransferases / Q000378:metabolism*; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000201:enzymology*; D012710:Serum Albumin, Bovine; D012867:Skin / Q000201:enzymology; D014357:Trypsin; D014465:Ultrasonics
chemical_list: D006150:Guanine Nucleotides; D007292:Inosine Nucleotides; D010428:Pentosephosphates; D012710:Serum Albumin, Bovine; D010430:Pentosyltransferases; D014357:Trypsin; D000225:Adenine