title: Selective tryptophan oxidation in the antitumor protein neocarzinostatin and effects on conformation and biological activity.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000903:Antibiotics, Antineoplastic / Q000032:analysis* / Q000494:pharmacology; D001426:Bacterial Proteins / Q000032:analysis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D004355:Drug Stability; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007945:Leukemia, Lymphoid / Q000097:blood; D008214:Lymphocytes / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009905:Optical Rotatory Dispersion; D010084:Oxidation-Reduction; D011487:Protein Conformation / Q000187:drug effects; D012505:Sarcina / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces; D013329:Structure-Activity Relationship; D013388:Succinimides; D014364:Tryptophan
chemical_list: D000596:Amino Acids; D000903:Antibiotics, Antineoplastic; D001426:Bacterial Proteins; D013388:Succinimides; D014364:Tryptophan