Erythrocyte deformation in human muscular dystrophy.
Erythrocytes from patients with congenital muscular dystrophy exhibit dramatic surface deformation when observed with a scanning electron microscope. A similar alteration, but one affecting a smaller proportion of cells, occurs in the case of female carriers of the sex-linked Duchenne dystrophic condition. These observed changes in the erythrocyte surface may reflect a systemic defect in membrane properties.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D004912:Erythrocytes; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007223:Infant; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009136:Muscular Dystrophies / Q000097:blood* / Q000151:congenital / Q000235:genetics; D012730:Sex Chromosomes; D012737:Sex Factors