[Changes in lactate dehydrogenase, glutamate-cxaloacetate transaminase and glutamate-pyruvate transaminase in several muscular atrophies. I. Changes following tenotomy].
The activites of lactic dehydrogenase (LDH), glutamicoxalactic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) are investigated within variable periods following tenotomy of m. gastrocnemius in the rat. A gradual fall of total activities is established, mostly significant for LDH, and least - for GPT. The specific activities undergo similar alterations. Experiments with dialysates show that the changes found are due to a reduced enzyme molecules' synthesis, and not to altered ratios between enzyme activators and inhibitors.
D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000201:enzymology*; D009133:Muscular Atrophy / Q000201:enzymology*; D051381:Rats; D013997:Time Factors
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Promeni v aktivnostti na laktat-dekhidrogenazata, glutamat-cksal-ctsetnata transaminaza i glutamat-piruvatnata transaminaza pri niakoi muskulni atrofii. I. Promeni sled tenotomiia