Proteolysis of myosin during platelet storage.
Physical properties of actomyosin from either fresh or stored platelets have been compared. Actomyosin obtained from platelets after 3 days of storage contained myosin that was 60-80% degraded to myosin rod. No myosin rod was detected in fresh platelets. The platelet myosin rod is similar to the rod produced by limited proteolysis of skeletal muscle myosin.
D000205:Actomyosin / Q000032:analysis*; D001792:Blood Platelets / Q000032:analysis; D001793:Blood Preservation; D002499:Centrifugation, Density Gradient; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008854:Microscopy, Electron; D009218:Myosins / Q000032:analysis*
D000205:Actomyosin; D009218:Myosins