Characterisation of cytochrome P-450 species in rat liver microsomes, I. Differences in the O-dealkylation of 7-ethoxycoumarin after pretreatment with phenobarbital and 3-methylcholanthrene.
D000818:Animals; D003374:Coumarins / Q000031:analogs & derivatives*; D003510:Cyclohexanes / Q000494:pharmacology; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003640:Dealkylation; D005019:Ethyl Ethers / Q000378:metabolism; D005260:Female; D005415:Flavins / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008748:Methylcholanthrene / Q000494:pharmacology*; D008797:Metyrapone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D010634:Phenobarbital / Q000494:pharmacology*; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
D003374:Coumarins; D003510:Cyclohexanes; D065607:Cytochrome P-450 Enzyme Inhibitors; D005019:Ethyl Ethers; D005415:Flavins; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D010634:Phenobarbital; D008797:Metyrapone