Benzo(a)pyrene metabolites: efficient and rapid separation by high-pressure liquid chromatography.
High-pressure liquid chromatography can separate eight metabolites of benzo[a] pyrene formed by rat liver microsomes. This method offers major advantages over previous techniques used for the separation of oxygenated polycyclic aromatic hydrocarbons.
D000818:Animals; D001580:Benzopyrenes / Q000302:isolation & purification* / Q000378:metabolism; D002247:Carbon Isotopes; D002845:Chromatography; D066298:In Vitro Techniques; D013058:Mass Spectrometry; D008722:Methods; D008862:Microsomes, Liver / Q000378:metabolism; D051381:Rats; D014316:Tritium
D001580:Benzopyrenes; D002247:Carbon Isotopes; D014316:Tritium