title: Blood fluorocarbon levels following exposure to household aerosols.
abstract: Measurement of blood fluorocarbon levels was carried out in subjects exposed to a number of household aerosol products containing fluorocarbon gases as propellants. All aerosols were used according to manufacturers' recommendations. The general purpose of the study was to determine whether with normal routine exposure to a wide variety of household aerosol products fluorocarbon could be found in the blood and if so, to check the potential toxicity of the levels reached. Daily exposure to aerosols according to the study regimen lasted four consecutive weeks; this period was preceded and followed by two weeks of abstention from exposure. At the end of each of the three periods a medical examination, including evaluation of cardiac function, respiratory function studies, and hematological and functional clinical biochemical tests was performed. All tests and assessments failed to show any indication of toxicity. No trace of fluorocarbon was found in any of the blood sampled at intervals during the study.
mesh_terms: D000328:Adult; D000335:Aerosol Propellants; D000336:Aerosols; D000368:Aged; D005617:Chlorofluorocarbons, Methane; D004781:Environmental Exposure; D005260:Female; D006334:Heart Function Tests; D006796:Household Work; D006801:Humans; D006845:Hydrocarbons, Fluorinated / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008875:Middle Aged; D012129:Respiratory Function Tests; D013997:Time Factors; D000637:Transaminases / Q000097:blood
chemical_list: D000335:Aerosol Propellants; D000336:Aerosols; D005617:Chlorofluorocarbons, Methane; D006845:Hydrocarbons, Fluorinated; D007770:L-Lactate Dehydrogenase; D000637:Transaminases