Measurement of side effects of drugs.
In a clinical trial of two antirheumatic agents two methods of collection of side effects were used, one with and the other without a check list of possible symptoms. Findings suggested that the use of a check list interfered with the collection of side effects. Known side effects of aspirin-tinnitus, deafness, and gastrointestinal disturbance-were more efficiently shown and symptoms not included in the check list were more likely to be reported when a check list was not used.
D000700:Analgesics / Q000009:adverse effects; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D001241:Aspirin / Q000009:adverse effects; D003638:Deafness / Q000139:chemically induced; D064420:Drug-Related Side Effects and Adverse Reactions; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D008487:Medical History Taking; D010647:Phenyl Ethers / Q000009:adverse effects; D011422:Propionates / Q000009:adverse effects; D013223:Statistics as Topic; D014012:Tinnitus / Q000139:chemically induced
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D010647:Phenyl Ethers; D011422:Propionates; D001241:Aspirin