Tritiated glycerol triether as an oil phase marker in man.
3H-labeled glycerol triether has been suggested as a marker of the oil phase during digestion and absorption of a lipid test meal. This study examines the behavior of this isotope in the human alimentary tract. The results suggest that it is completely recovered from the gastrointestinal tract, and thus it remains solely with the oil phase of emulsions in vivo and with the oil phase of intestinal aspirates. (3)H-labeled glycerol triether may thus be an appropriate marker of the oil phase for use in human studies of lipid absorption.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002250:Carbon Radioisotopes; D002855:Chromatography, Thin Layer; D004063:Digestion; D004655:Emulsions; D004987:Ethers / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D005243:Feces / Q000032:analysis; D005260:Female; D005374:Filtration; D005990:Glycerol / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine / Q000031:analogs & derivatives; D006801:Humans; D007408:Intestinal Absorption; D007419:Intestinal Secretions / Q000032:analysis; D007583:Jejunum; D008297:Male; D008875:Middle Aged; D009829:Oleic Acids / Q000378:metabolism; D013997:Time Factors; D014316:Tritium; D014461:Ultracentrifugation
D002250:Carbon Radioisotopes; D004655:Emulsions; D004987:Ethers; D009829:Oleic Acids; D014316:Tritium; C007868:glycerol triether; D005990:Glycerol