The nature and significance of hyperamylasemia follwing operation.
Total serum amylase activity was found to be significantly elevated postoperatively in 11 (10%) of 110 patients undergoing various surgical procedures. Isoamylase analysis revealed that the rise was chiefly in the pancreatic-type isoamylase in seven of the 11 patients showing postoperative serum amylase elevations; in the other four patients, the elevation occurred principally in the salivary-type isoamylase. These data demonstrate that postoperative hyperamylasemia occurs surprisingly often and that serum amylase activity may rise even when the surgical procedure is extra-abdominal. Moreover, elevation of serum amylase activity after surgery is not necessarily an indication of pancreatitis and may reflect instead a rise in salivary-type isoamylase.
D000005:Abdomen / Q000601:surgery; D000681:Amylases / Q000097:blood*; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D010179:Pancreas / Q000201:enzymology; D010195:Pancreatitis / Q000175:diagnosis / Q000201:enzymology; D011183:Postoperative Complications / Q000175:diagnosis; D012469:Salivary Glands / Q000201:enzymology; D013514:Surgical Procedures, Operative; D013997:Time Factors
D007527:Isoenzymes; D000681:Amylases