Ribosomal RNA synthesis in chronic lymphocytic leukaemia.
Lymphocytes from patients with chronic lymphocytic leukaemia make large amounts of stable, rapidly labelled high molecular weight RNA, but ribosomal RNA methylation is normal. However, fewer ribosomes are available for protein synthesis than in normal lymphocytes.
D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007945:Leukemia, Lymphoid / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism; D046911:Macromolecular Substances; D008745:Methylation; D012335:RNA, Ribosomal / Q000096:biosynthesis*; D012343:RNA, Transfer / Q000096:biosynthesis; D012270:Ribosomes / Q000378:metabolism; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D046911:Macromolecular Substances; D012335:RNA, Ribosomal; D014316:Tritium; D012343:RNA, Transfer; D014529:Uridine