Structural aspects of manganese-pyruvate kinase substrate and inhibitor complexes deduced from proton magnetic relaxation rates of pyruvate and a phosphoenolpyruvate analog.
D000179:Acrylates / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000378:metabolism*; D008433:Mathematics; D009132:Muscles / Q000201:enzymology*; D009994:Osmolar Concentration; D010721:Phosphinic Acids / Q000378:metabolism; D010728:Phosphoenolpyruvate / Q000378:metabolism*; D011485:Protein Binding; D011522:Protons; D011770:Pyruvate Kinase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism*; D011817:Rabbits; D013329:Structure-Activity Relationship; D013696:Temperature
D000179:Acrylates; D010721:Phosphinic Acids; D011522:Protons; D011773:Pyruvates; D008345:Manganese; D010728:Phosphoenolpyruvate; D000255:Adenosine Triphosphate; D011770:Pyruvate Kinase