Inhibition of DNA repair by the 1,3-bis(2-chloroethyl)-1-nitrosourea breakdown product, 2-chloroethyl isocyanate.
D000818:Animals; D002330:Carmustine / Q000378:metabolism*; D002478:Cells, Cultured; D003485:Cyanates / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology; D004260:DNA Repair / Q000187:drug effects*; D004273:DNA, Neoplasm / Q000528:radiation effects*; D004277:DNA, Single-Stranded; D003609:Dactinomycin / Q000494:pharmacology; D003864:Depression, Chemical; D005021:Ethylamines / Q000494:pharmacology; D006918:Hydroxyurea / Q000494:pharmacology; D017953:Isocyanates; D007939:Leukemia L1210; D051379:Mice; D009150:Mustard Compounds / Q000494:pharmacology*; D011830:Radiation Effects
D003485:Cyanates; D004273:DNA, Neoplasm; D004277:DNA, Single-Stranded; D005021:Ethylamines; D017953:Isocyanates; D009150:Mustard Compounds; C006995:2-chloroethyl isocyanate; D003609:Dactinomycin; D003513:Cycloheximide; D002330:Carmustine; D006918:Hydroxyurea