title: Linoleate and fatty-acid patterns of serum lipids in multiple sclerosis and other diseases.
abstract: The linoleic acid content of serum lipids was measured in 47 patients with multiple sclerosis, 29 patients with other neurological diseases, 35 patients with acute non-neurological illnesses, and 49 healthy control subjects. Reduced linoleic acid content of serum lipids was not specific to multiple sclerosis and occurred in all ill patients with acute non-neurological illness. The fatty-acid pattern of serum lipids in illness resembles that of essential fatty-acid deficiency. It seems that this pattern of reduced linoleic acid content with increased oleic, palmitic, and palmitoleic acid content may be a general phenomenon in ill patients.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000740:Anemia / Q000097:blood; D002784:Cholesterol / Q000097:blood; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D008041:Linoleic Acids / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000097:blood*; D009203:Myocardial Infarction / Q000097:blood; D009829:Oleic Acids / Q000097:blood; D010169:Palmitic Acids / Q000097:blood; D012141:Respiratory Tract Infections / Q000097:blood
chemical_list: D005227:Fatty Acids; D008041:Linoleic Acids; D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D002784:Cholesterol