Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen.
D000082:Acetaminophen / Q000494:pharmacology* / Q000506:poisoning; D000818:Animals; D001665:Binding Sites; D056486:Chemical and Drug Induced Liver Injury; D006224:Cricetinae; D005978:Glutathione / Q000378:metabolism*; D006168:Guinea Pigs; D008099:Liver / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D008107:Liver Diseases / Q000378:metabolism* / Q000473:pathology; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D009336:Necrosis / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013997:Time Factors; D014316:Tritium
D014316:Tritium; D000082:Acetaminophen; D005978:Glutathione