Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.
D000818:Animals; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003857:Deoxyuridine / Q000378:metabolism; D004347:Drug Interactions; D005492:Folic Acid; D007939:Leukemia L1210 / Q000201:enzymology; D008727:Methotrexate / Q000494:pharmacology; D008780:Methyltransferases / Q000378:metabolism*; D051379:Mice; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*; D013940:Thymidylate Synthase / Q000378:metabolism; D014316:Tritium
D004273:DNA, Neoplasm; D014316:Tritium; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D008780:Methyltransferases; D013940:Thymidylate Synthase; D003857:Deoxyuridine; D008727:Methotrexate