Burn scar carcinoma and hypercalcemia.
A case of a patient with burn scar carcinoma of an extremity associated with hypercalcemia and without bone metastasis is presented. From the data presented, it seems reasonable to assume that this squamous cell carcinoma of a burn scar secreted some type of parathyroid hormone-like substance or substances which posessed calcium-increasing biological activity resulting in hypercalcemia.
D000328:Adult; D000671:Amputation, Surgical; D001132:Arm; D001365:Axilla; D001798:Blood Proteins / Q000032:analysis; D002056:Burns / Q000150:complications*; D002118:Calcium / Q000097:blood; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000601:surgery; D002921:Cicatrix / Q000150:complications*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008297:Male; D009364:Neoplasm Recurrence, Local; D009384:Paraneoplastic Endocrine Syndromes; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011863:Radioimmunoassay; D012878:Skin Neoplasms / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000601:surgery; D012883:Skin Ulcer / Q000150:complications
D001798:Blood Proteins; D010281:Parathyroid Hormone; D010758:Phosphorus; D002118:Calcium