The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT).
D000630:Aminopterin / Q000494:pharmacology; D001345:Autoradiography; D001375:Azaguanine / Q000494:pharmacology*; D002460:Cell Line; D002999:Clone Cells; D003470:Culture Media; D004351:Drug Resistance; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology; D006147:Guanine; D006801:Humans; D007042:Hypoxanthines / Q000378:metabolism; D066298:In Vitro Techniques; D007926:Lesch-Nyhan Syndrome; D008297:Male; D009154:Mutation; D010413:Penis; D010430:Pentosyltransferases / Q000378:metabolism*; D011336:Probability; D013936:Thymidine / Q000494:pharmacology; D014316:Tritium
D003470:Culture Media; D007042:Hypoxanthines; D014316:Tritium; D006147:Guanine; D010430:Pentosyltransferases; D000630:Aminopterin; D001375:Azaguanine; D013936:Thymidine