Steroid 11beta-hydroxylation in beef adrenal cortex mitochondria. Binding affinity and capacity of specific (14C)steroids and for (3H)metyrapol, an inhibitor of the 11beta-hydroxylation reaction.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism*; D000735:Androstenedione / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002250:Carbon Radioisotopes; D002417:Cattle; D002784:Cholesterol / Q000378:metabolism; D003510:Cyclohexanes / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003900:Desoxycorticosterone / Q000378:metabolism; D006900:Hydroxylation; D008797:Metyrapone / Q000378:metabolism* / Q000494:pharmacology; D008861:Microsomes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D009570:Nitriles / Q000494:pharmacology; D013250:Steroid Hydroxylases; D013256:Steroids / Q000378:metabolism* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013739:Testosterone / Q000378:metabolism; D013816:Thermodynamics; D014316:Tritium
D002250:Carbon Radioisotopes; D003510:Cyclohexanes; D009570:Nitriles; D013256:Steroids; D014316:Tritium; D013739:Testosterone; D000735:Androstenedione; D003900:Desoxycorticosterone; D003577:Cytochrome P-450 Enzyme System; D002784:Cholesterol; D013250:Steroid Hydroxylases; D008797:Metyrapone