Alpha-1-acetylmethadol and its N-demethylated metabolites have potent opiate action in the guinea pig isolated ileum.
D000085:Acetates / Q000378:metabolism / Q000494:pharmacology; D000700:Analgesics / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D004558:Electric Stimulation; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects / Q000502:physiology*; D008691:Methadone / Q000378:metabolism / Q000494:pharmacology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology; D012044:Regression Analysis; D013329:Structure-Activity Relationship
D000085:Acetates; D000700:Analgesics; D009270:Naloxone; D008691:Methadone