title: Immediate hypersensitivity responses in flatfish.
abstract: Fungal extracts that precipitate with human C-reactive protein caused immediate erythema on subdermal injection into marine flatfish. Only species with calcium-dependent serum precipitins to these fungi showed skin reactions. Immediate hypersensitivity in a nonreactive species could be induced after injection with serum from reactive species. The transferable serum factor (or factors) was heat sensitive.
mesh_terms: D000485:Allergens; D000818:Animals; D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D002097:C-Reactive Protein; D003429:Cross Reactions; D005399:Fishes / Q000276:immunology*; D005658:Fungi / Q000276:immunology; D006358:Hot Temperature; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007116:Immunization, Passive; D007073:Immunoglobulin E; D010323:Passive Cutaneous Anaphylaxis; D011234:Precipitins; D012882:Skin Tests; D013045:Species Specificity
chemical_list: D000485:Allergens; D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D011234:Precipitins; D007073:Immunoglobulin E; D002097:C-Reactive Protein