Cyclization of the phosphate side chain of adenosine triphosphate: formation of monoadenosine 5'-trimetaphosphate.
Monoadenosine 5'-trimetaphosphate has been prepared from adeno-sine 5'-triphosphate by a carbodiimide-mediated condensation. The molecule was characterized by (3l)P nuclear magnetic resonance, and its (31)P spectrum was simulated through the assumption of a three-phosphorus spin system. The molecule is highly reactive and is rapidly converted to adenosine triphosphate upon contact with water.
D000255:Adenosine Triphosphate; D002234:Carbodiimides; D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D006865:Hydrogenation; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D009712:Nucleotides, Cyclic / Q000138:chemical synthesis*; D010759:Phosphorus Isotopes; D014867:Water
D002234:Carbodiimides; D009712:Nucleotides, Cyclic; D010759:Phosphorus Isotopes; D014867:Water; D000255:Adenosine Triphosphate