title: Human acid phosphatase in somatic cell hybrids.
abstract: The human enzyme, lysosomal acid phosphatase ACP2, is expressed in nan-rodent somatic cell hybrids as a dimeric molecule. The human-rodent heteropolymer, as well as the human and rodent homopolymer, is associated with lysosomes in these cells. The genes specifying lysosomal acid phosphatase ACP(2) and LDH A are syntenic.
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis / Q000096:biosynthesis*; D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002999:Clone Cells / Q000201:enzymology; D006224:Cricetinae; D004592:Electrophoresis, Starch Gel; D005260:Female; D005347:Fibroblasts; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology*; D007527:Isoenzymes / Q000096:biosynthesis*; D007770:L-Lactate Dehydrogenase / Q000096:biosynthesis; D007962:Leukocytes; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D051379:Mice
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D000135:Acid Phosphatase