title: Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediate.
mesh_terms: D000215:Acylation; D000818:Animals; D001565:Benzoates / Q000378:metabolism; D001665:Binding Sites; D001667:Binding, Competitive; D002250:Carbon Radioisotopes; D002384:Catalysis; D002417:Cattle; D002918:Chymotrypsin / Q000378:metabolism*; D002919:Chymotrypsinogen / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D002942:Circular Dichroism; D004789:Enzyme Activation; D006146:Guanidines / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007531:Isoflurophate / Q000378:metabolism; D007700:Kinetics; D009578:Nitrobenzenes / Q000378:metabolism; D009943:Organophosphorus Compounds; D011422:Propionates; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D013552:Swine; D014362:Trypsinogen / Q000037:antagonists & inhibitors
chemical_list: D001565:Benzoates; D002250:Carbon Radioisotopes; D006146:Guanidines; D009578:Nitrobenzenes; D009943:Organophosphorus Compounds; D011422:Propionates; D007531:Isoflurophate; D014362:Trypsinogen; D002919:Chymotrypsinogen; D002918:Chymotrypsin