title: Platelet and plasma fibrinogens are identical gene products.
abstract: Human platelet fibrinogen has been shown to be indistinguishable from plasma fibrinogen by a variety of criteria, including subunit composition and cross-linking characteristics as judged by sodium dodecyl sulfate-gel electro phoresis, quantitative amino terminal analysis of fibrin, and the amino acid compositions of fibrinopeptides released from platelet and plasma fibrinogens is products of the same gene or genes.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001792:Blood Platelets / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005337:Fibrin / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis / Q000096:biosynthesis*; D005796:Genes; D005815:Genetic Code; D006801:Humans; D010455:Peptides / Q000032:analysis / Q000302:isolation & purification; D014176:Protein Biosynthesis; D011487:Protein Conformation; D012967:Sodium Dodecyl Sulfate
chemical_list: D000596:Amino Acids; D010455:Peptides; D012967:Sodium Dodecyl Sulfate; D005337:Fibrin; D005340:Fibrinogen