An in vitro study of cytostatic drug effect on the drug effect on the DNA synthesis in methylcholanthrene induced mouse sarcomas. Correlation between in vitro results and the response in vivo.
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D003561:Cytarabine / Q000494:pharmacology / Q000627:therapeutic use*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003864:Depression, Chemical; D004351:Drug Resistance; D005260:Female; D066298:In Vitro Techniques; D007958:Leukocyte Count; D008558:Melphalan / Q000494:pharmacology / Q000627:therapeutic use*; D008748:Methylcholanthrene; D051379:Mice; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism; D013268:Stimulation, Chemical; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014184:Transplantation, Homologous; D014316:Tritium; D014747:Vinblastine / Q000494:pharmacology / Q000627:therapeutic use*
D004273:DNA, Neoplasm; D003561:Cytarabine; D014316:Tritium; D008748:Methylcholanthrene; D014747:Vinblastine; D008558:Melphalan; D013936:Thymidine