Detection of a gonadotropin in rabbit blastocyst before implantation.
A gonadotropin similar to human chorionic gonadotropin or luteinizing hormone has been demonstrated in rabbit blastocyst prior to implantation. The gonadotropin has been detected by a radioreceptor assay for human chorionic gonadotropin with the use of the plasma membranes of bovine corpora lutea obtained during the first trimester of pregnancy. The concentrations of the human chorionic gonadotropin or luteinizing hormone per milliliter of blastocyst fluid were tenfold higher than those in the blood of pregnant rabbits on days 5 and 6 after mating.
D000818:Animals; D001667:Binding, Competitive; D001755:Blastocyst / Q000032:analysis / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D006063:Chorionic Gonadotropin / Q000097:blood / Q000378:metabolism; D003338:Corpus Luteum / Q000378:metabolism; D010064:Embryo Implantation; D005260:Female; D006062:Gonadotropins / Q000032:analysis / Q000096:biosynthesis*; D006801:Humans; D007457:Iodine Radioisotopes; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D011247:Pregnancy; D011258:Pregnancy Tests; D011485:Protein Binding; D011817:Rabbits; D011869:Radioligand Assay
D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D007457:Iodine Radioisotopes; D007986:Luteinizing Hormone