The kinetics of intramolecular distribution of 15N in uric acid following administration of 15N-glycine: preferential labeling of N-(3+9) of uric acid in primary gout and a reappraisal of the "glutamine hypothesis".
D000293:Adolescent; D000328:Adult; D002852:Chromatography, Ion Exchange; D005973:Glutamine / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D006073:Gout / Q000235:genetics / Q000378:metabolism* / Q000652:urine; D006150:Guanine Nucleotides; D006626:Hippurates / Q000652:urine; D006801:Humans; D007042:Hypoxanthines; D007292:Inosine Nucleotides; D008297:Male; D013058:Mass Spectrometry; D008433:Mathematics; D008875:Middle Aged; D009587:Nitrogen Isotopes; D010430:Pentosyltransferases / Q000378:metabolism; D013053:Spectrophotometry; D013997:Time Factors; D014527:Uric Acid / Q000096:biosynthesis*
D006150:Guanine Nucleotides; D006626:Hippurates; D007042:Hypoxanthines; D007292:Inosine Nucleotides; D009587:Nitrogen Isotopes; D005973:Glutamine; D014527:Uric Acid; D010430:Pentosyltransferases; D005998:Glycine