Anemia in domestic cats: effect on hemoglobin components and whole blood oxygenation.
Phenylhydrazine-induced anemia in the domestic cat results in an increase in minor, high oxygen affinity hemoglobin B components and an accompanying decrease in the major, low affinity B component. This change is accompanied by an unusually large increase in erythrocytic adenosine triphosphate and 2,3-diphosphoglycerate, a slight decrease in the oxygen affinity of whole blood, and a large decrease in the Hill constant.
D000255:Adenosine Triphosphate / Q000032:analysis; D000740:Anemia / Q000097:blood* / Q000139:chemically induced; D000818:Animals; D001772:Blood Cell Count; D002415:Cats; D002852:Chromatography, Ion Exchange; D004163:Diphosphoglyceric Acids / Q000032:analysis; D004912:Erythrocytes / Q000032:analysis*; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis*; D007700:Kinetics; D010100:Oxygen / Q000097:blood*; D010659:Phenylhydrazines; D012156:Reticulocytes
D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D010659:Phenylhydrazines; D000255:Adenosine Triphosphate; D010100:Oxygen