Action of (S)-and(R)-para-substituted amphetamine hydrochlorides and (alphaS)-and (alphaR)-p-chloronorephedrine and (alphaS)-and (alphaR)-p-chloronorpseudoephedrine hydrochlorides on the level of 5-hydroxytryptamine and the activity of tryptophan hydroxylase in rat brain.
D000661:Amphetamine / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002713:Chlorine / Q000494:pharmacology; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008968:Molecular Conformation; D009574:Nitro Compounds / Q000494:pharmacology; D010627:Phenethylamines / Q000138:chemical synthesis / Q000494:pharmacology*; D010665:Phenylpropanolamine / Q000031:analogs & derivatives; D011412:Propanolamines / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D012702:Serotonin Antagonists; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014365:Tryptophan Hydroxylase / Q000037:antagonists & inhibitors
D009574:Nitro Compounds; D010627:Phenethylamines; D011412:Propanolamines; D012702:Serotonin Antagonists; C007011:4-chloronorephedrine; D010665:Phenylpropanolamine; D002713:Chlorine; C007012:4-chloronorpseudoephedrine; D000661:Amphetamine; D014365:Tryptophan Hydroxylase