Double-blind comparison of phlebitis produced by cephalothin infusions with buffered and unbuffered diluents.
In a double-blind study with each patient as his own control, a buffered and an unbuffered cephalothin solution was administered to 13 patients in opposite arms for a period of 48 h each. Neither the incidence of phlebitis nor the degree of phlebitis was different with the two diluents, and there was no difference in the time of onset of phlebitis.
D002021:Buffers; D002512:Cephalothin / Q000009:adverse effects*; D006801:Humans; D010689:Phlebitis / Q000139:chemically induced*
D002021:Buffers; D002512:Cephalothin