title: Potential inhibitor of S-adenosylmethionine-dependent methyltransferases. 2. Modification of the base portion of S-adenosylhomocysteine.
mesh_terms: D000241:Adenosine / Q000138:chemical synthesis* / Q000494:pharmacology; D000313:Adrenal Medulla / Q000201:enzymology; D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000201:enzymology; D065098:Catechol O-Methyltransferase Inhibitors; D002417:Cattle; D006168:Guinea Pigs; D006632:Histamine; D006710:Homocysteine / Q000138:chemical synthesis* / Q000494:pharmacology; D007211:Indoles; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D010625:Phenylethanolamine N-Methyltransferase / Q000037:antagonists & inhibitors; D010870:Pineal Gland / Q000201:enzymology; D011485:Protein Binding / Q000187:drug effects; D051381:Rats; D012436:S-Adenosylmethionine; D013329:Structure-Activity Relationship
chemical_list: D065098:Catechol O-Methyltransferase Inhibitors; D007211:Indoles; D006710:Homocysteine; D012436:S-Adenosylmethionine; D006632:Histamine; D008780:Methyltransferases; D010625:Phenylethanolamine N-Methyltransferase; D000241:Adenosine