title: Mechanism of action of coumarins. Significance of vitamin K epoxide.
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology; D003374:Coumarins / Q000494:pharmacology*; D004988:Ethers, Cyclic / Q000378:metabolism* / Q000494:pharmacology; D007020:Hypoprothrombinemias / Q000139:chemically induced; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D011516:Prothrombin / Q000096:biosynthesis*; D051381:Rats; D013329:Structure-Activity Relationship; D014316:Tritium; D014812:Vitamin K / Q000037:antagonists & inhibitors; D010837:Vitamin K 1 / Q000378:metabolism* / Q000494:pharmacology; D014813:Vitamin K Deficiency / Q000378:metabolism; D014859:Warfarin / Q000494:pharmacology
chemical_list: D000925:Anticoagulants; D003374:Coumarins; D004988:Ethers, Cyclic; D014316:Tritium; D014812:Vitamin K; D014859:Warfarin; D010837:Vitamin K 1; D011516:Prothrombin