Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones.
D000478:Alkylation; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects; D001552:Benzazepines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D002490:Central Nervous System / Q000187:drug effects*; D002707:Chlordiazepoxide / Q000494:pharmacology; D006224:Cricetinae; D003500:Cyclization; D003864:Depression, Chemical; D003975:Diazepam / Q000494:pharmacology; D004357:Drug Synergism; D004597:Electroshock; D005106:Exploratory Behavior / Q000187:drug effects; D006591:Hexobarbital / Q000494:pharmacology; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D007928:Lethal Dose 50; D013058:Mass Spectrometry; D008694:Methamphetamine / Q000037:antagonists & inhibitors; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009129:Muscle Tonus / Q000187:drug effects; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D012018:Reflex / Q000187:drug effects; D012890:Sleep / Q000187:drug effects
D000927:Anticonvulsants; D001552:Benzazepines; D006993:Hypnotics and Sedatives; D008694:Methamphetamine; D002707:Chlordiazepoxide; D006591:Hexobarbital; D003975:Diazepam; D010433:Pentylenetetrazole