Dimethylsulfoxide increases the lethality of CCl4 in rats but decreases its hepatotoxicity.
D000818:Animals; D002251:Carbon Tetrachloride / Q000633:toxicity*; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D006591:Hexobarbital / Q000494:pharmacology; D007928:Lethal Dose 50; D008099:Liver / Q000378:metabolism; D008111:Liver Function Tests; D008297:Male; D051381:Rats; D012890:Sleep / Q000187:drug effects; D013448:Sulfobromophthalein; D014280:Triglycerides / Q000378:metabolism
D014280:Triglycerides; D013448:Sulfobromophthalein; D006591:Hexobarbital; D002251:Carbon Tetrachloride; D004121:Dimethyl Sulfoxide