Increase of hexobarbital sleeping time and inhibition of drug metabolism by the major metabolite of diphenylhydantoin.
D000818:Animals; D004347:Drug Interactions; D006591:Hexobarbital / Q000378:metabolism* / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009019:Morphinans / Q000378:metabolism*; D010672:Phenytoin / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D012890:Sleep / Q000187:drug effects*; D013997:Time Factors
D009019:Morphinans; D010672:Phenytoin; D006591:Hexobarbital