title: Complications of carbenoxolone therapy.
abstract: Side effects from carbenoxolone are common and are due to electrolyte disturbance, such as sodium retention and hypokalaemia. They occur particularly in the elderly, who may already be being treated for other illnesses. Eight patients are described with serious side effects from carbenoxolone therapy, some of which were unrecognized for some time because of inadequate follow-up or because clinicians were unfamiliar with them.
mesh_terms: D000368:Aged; D005260:Female; D006035:Glycyrrhiza; D006261:Headache / Q000139:chemically induced; D006331:Heart Diseases / Q000139:chemically induced; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007008:Hypokalemia / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000188:drug therapy; D010946:Plants, Medicinal; D012964:Sodium / Q000378:metabolism*; D013386:Succinates / Q000009:adverse effects; D013729:Terpenes / Q000627:therapeutic use; D014315:Triterpenes / Q000009:adverse effects*; D014882:Water-Electrolyte Balance
chemical_list: D013386:Succinates; D013729:Terpenes; D014315:Triterpenes; D012964:Sodium