Administration of ticarcillin, a new antipseudomonal antibiotic, in patients undergoing dialysis.
Ticarcillin was administered to three groups of patients in chronic renal failure; three were undergoing chronic hemodialysis, two were undergoing peritoneal dialysis, and three received the drug after hemodialysis. The serum half-lives were measured. A dosage regime for patients undergoing dialysis is suggested.
D002264:Carboxylic Acids / Q000378:metabolism; D006207:Half-Life; D006801:Humans; D010406:Penicillins / Q000378:metabolism*; D010530:Peritoneal Dialysis; D011549:Pseudomonas / Q000187:drug effects*; D006435:Renal Dialysis; D013876:Thiophenes / Q000378:metabolism*
D002264:Carboxylic Acids; D010406:Penicillins; D013876:Thiophenes