title: On the methylated purine content of tRNA present in tumours.
abstract: The methylated purine content of tRNA bulk extracted from human hepatomata has been compared with that in normal human liver. The analyses were carried out with the aid of ion-exchange chromatography. The molar proportions of 5 bases detected in acid hydrolysates of tumour tRNA (N(2)-methylguanine, 1-methylguanine, 7-methylguanine, N(2)-dimethylguanine and 1-methyladenine) were not abnormally elevated.
mesh_terms: D002852:Chromatography, Ion Exchange; D006406:Hematoma / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism*; D008745:Methylation; D011687:Purines / Q000032:analysis* / Q000378:metabolism; D012343:RNA, Transfer / Q000032:analysis*; D013329:Structure-Activity Relationship
chemical_list: D011687:Purines; D012343:RNA, Transfer