Growth hormone responses to melatonin in man.
Oral administration of 1 gram of melatonin caused rapid and significant elevations of serum human growth hormone in eight out of nine normal male subjects. The mean (+/- standard error of the mean) of the peak response by growth hormone was 22.9 +/- 4.6 microunits per milliliter. The increased secretion of growth hormone may be due to interaction of melatonin with hypothalamic serotoninergic receptors.
D000284:Administration, Oral; D013006:Growth Hormone / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000008:administration & dosage / Q000494:pharmacology*; D013268:Stimulation, Chemical
D013006:Growth Hormone; D008550:Melatonin