Analysis of mercurial preservatives in bacterins, vaccines, and antisera by atomic absorption spectrophotometry.
A flameless atomic absorption method was developed for the determination of mercurial preservatives in biologicals. The assay was based on a quantitative determination of the mercury content of these preservatives. This method was used to analyze a variety of samples and yielded reproducible results with satisfactory recoveries. The procedure is presented in a simplified block diagram and described in detail relating its suitability for routine assay of large numbers of samples.
D001430:Bacteriocins / Q000032:analysis; D001688:Biological Products / Q000032:analysis*; D004356:Drug Storage; D006898:Hydroxylamines; D007106:Immune Sera / Q000032:analysis; D008628:Mercury / Q000032:analysis*; D010592:Pharmaceutic Aids / Q000032:analysis; D013054:Spectrophotometry, Atomic / Q000295:instrumentation; D014612:Vaccines / Q000032:analysis
D001430:Bacteriocins; D001688:Biological Products; D006898:Hydroxylamines; D007106:Immune Sera; D010592:Pharmaceutic Aids; D014612:Vaccines; D008628:Mercury