Structure-function relationship in the 12,13-epoxytrichothecenes. Novel inhibitors of protein synthesis.
D000818:Animals; D001584:Benzoxepins / Q000494:pharmacology; D001798:Blood Proteins / Q000096:biosynthesis*; D002250:Carbon Radioisotopes; D004988:Ethers, Cyclic / Q000494:pharmacology; D007700:Kinetics; D009183:Mycotoxins / Q000494:pharmacology*; D010441:Peptide Chain Elongation, Translational / Q000187:drug effects; D010442:Peptide Chain Initiation, Translational / Q000187:drug effects; D010443:Peptide Chain Termination, Translational / Q000187:drug effects; D010453:Peptide Synthases / Q000378:metabolism; D010649:Phenylalanine; D011817:Rabbits; D012156:Reticulocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism; D012717:Sesquiterpenes / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D001584:Benzoxepins; D001798:Blood Proteins; D002250:Carbon Radioisotopes; D004988:Ethers, Cyclic; D009183:Mycotoxins; D012717:Sesquiterpenes; D010649:Phenylalanine; D010453:Peptide Synthases