Stereoselective demethylation of the enantiomers of nefopam, an experimental antidepressant and skeletal muscle relaxant.
D000328:Adult; D000535:Aluminum; D000818:Animals; D000928:Antidepressive Agents / Q000378:metabolism*; D001392:Azocines / Q000378:metabolism*; D001555:Benzene Derivatives / Q000378:metabolism; D002845:Chromatography; D002849:Chromatography, Gas; D005260:Female; D006801:Humans; D007536:Isomerism; D007700:Kinetics; D008099:Liver / Q000166:cytology / Q000201:enzymology*; D008297:Male; D013058:Mass Spectrometry; D008433:Mathematics; D009467:Neuromuscular Depolarizing Agents / Q000378:metabolism*; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013053:Spectrophotometry; D013347:Subcellular Fractions / Q000201:enzymology
D000928:Antidepressive Agents; D001392:Azocines; D001555:Benzene Derivatives; D009467:Neuromuscular Depolarizing Agents; D000535:Aluminum; D010089:Oxidoreductases, N-Demethylating