Pharmacokinetics of the enantiomers of hexobarbital studied in the same intact rat and in the same isolated perfused rat liver.
D000818:Animals; D002417:Cattle; D002849:Chromatography, Gas; D003956:Dialysis; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D006591:Hexobarbital / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology; D007275:Injections, Intravenous; D007536:Isomerism; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D010477:Perfusion; D011485:Protein Binding; D051381:Rats; D012710:Serum Albumin, Bovine / Q000378:metabolism; D012890:Sleep / Q000187:drug effects; D013237:Stereoisomerism
D012710:Serum Albumin, Bovine; D006591:Hexobarbital