title: The significance of laboratory studies in the evaluation and discovery of psychoactive agents in man.
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology; D001362:Avoidance Learning / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects; D002707:Chlordiazepoxide / Q000266:history; D002746:Chlorpromazine / Q000266:history / Q000494:pharmacology; D002986:Clinical Trials as Topic; D003214:Conditioning, Classical / Q000187:drug effects; D003216:Conditioning, Operant / Q000187:drug effects; D013181:Cortical Spreading Depression / Q000187:drug effects; D004594:Electrophysiology; D049673:History, 20th Century; D006801:Humans; D007099:Imipramine / Q000266:history; D001523:Mental Disorders / Q000188:drug therapy; D008615:Mephenesin / Q000266:history; D008722:Methods; D011600:Psychopharmacology / Q000266:history*; D012106:Research
chemical_list: D000928:Antidepressive Agents; D002707:Chlordiazepoxide; D008615:Mephenesin; D007099:Imipramine; D002746:Chlorpromazine