Motor effects of copper in the caudate nucleus: reversible lesions with ion-exchange resin beads.
A method employing the use of ion-exchange resin beads is described for the punctate introduction of discrete amounts of various anions, cations, or zwitterions into given brain regions. A series of experiments utilizing the method to introduce ionic copper into the caudate nucleus with the resulting motor manifestations are discussed.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects / Q000502:physiology*; D003300:Copper / Q000494:pharmacology*; D007475:Ion Exchange Resins / Q000494:pharmacology*; D008722:Methods; D009043:Motor Activity / Q000187:drug effects*; D009069:Movement Disorders / Q000139:chemically induced; D013238:Stereotaxic Techniques
D007475:Ion Exchange Resins; D003300:Copper