title: Human C'3: evidence for the liver as the primary site of synthesis.
abstract: The liver is the primary, if not sole, site of synthesis of the third component of human complement, as shown by a change in the recipient from C'3 FS(0.6) to C'3 SS, the donor type, following homotransplantation of the liver.
mesh_terms: D000293:Adolescent; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001379:Azathioprine / Q000494:pharmacology; D001797:Blood Protein Electrophoresis; D002648:Child; D003165:Complement System Proteins / Q000096:biosynthesis*; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D008099:Liver / Q000276:immunology* / Q000378:metabolism; D016031:Liver Transplantation; D008297:Male; D008967:Molecular Biology; D011110:Polymorphism, Genetic; D011241:Prednisone / Q000494:pharmacology; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
chemical_list: D000961:Antilymphocyte Serum; D006242:Haptoglobins; D003165:Complement System Proteins; D001379:Azathioprine; D011241:Prednisone