The mechanism of action of methotrexate. II. Augmentation by vincristine of inhibition of deoxyribonucleic aic synthesis by methotrexate in Ehrlich ascites tumor cells.
D000818:Animals; D001665:Binding Sites / Q000187:drug effects; D002250:Carbon Radioisotopes; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003857:Deoxyuridine / Q000378:metabolism; D003864:Depression, Chemical; D004357:Drug Synergism; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D008815:Mice, Inbred Strains; D013997:Time Factors; D014316:Tritium; D014750:Vincristine / Q000494:pharmacology*
D002250:Carbon Radioisotopes; D004273:DNA, Neoplasm; D014316:Tritium; D014750:Vincristine; D003857:Deoxyuridine; D008727:Methotrexate