title: Congenital malformations induced by mescaline, lysergic acid diethylamide, and bromolysergic acid in the hamster.
abstract: Malformations of the brain, spinal cord, liver, and other viscera; body edema; and localized hemorrhages were found in fetal hamsters from mothers injected subcutaneously with a single dose of mescaline, lysergic acid diethylamide, or 2-bromo-D lysergic acid diethylamide on the 8th day of pregnancy. In addition, all three drugs produced an increase in the percentages of small fetuses per litter, of resorptions, and of fetal mortality.
mesh_terms: D000014:Abnormalities, Drug-Induced; D000818:Animals; D001921:Brain / Q000002:abnormalities; D006224:Cricetinae; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects; D006086:Graft vs Host Disease / Q000139:chemically induced; D006213:Hallucinogens / Q000633:toxicity*; D006470:Hemorrhage / Q000139:chemically induced; D008238:Lysergic Acid Diethylamide / Q000633:toxicity*; D008635:Mescaline / Q000633:toxicity*; D011247:Pregnancy; D011270:Pregnancy, Animal; D016135:Spinal Dysraphism / Q000139:chemically induced
chemical_list: D006213:Hallucinogens; D008238:Lysergic Acid Diethylamide; D008635:Mescaline