title: Intracellular concentration of cysteine in Escherichia coli and its relation to repression of the sulphate-activating enzymes.
abstract: 1. The intracellular cysteine and glutathione concentrations were measured in Escherichia coli under a variety of growth conditions. 2. An inverse relation between intracellular cysteine concentration and the specific activity of the sulphate-activating enzymes was found. 3. This is compatible with the view that the intracellular cysteine concentration controls the rate of synthesis of these enzymes.
mesh_terms: D000227:Adenine Nucleotides / Q000096:biosynthesis*; D002247:Carbon Isotopes; D002854:Chromatography, Paper; D003545:Cysteine / Q000378:metabolism*; D004794:Enzyme Repression; D004926:Escherichia coli / Q000378:metabolism*; D005033:Ethylmaleimide / Q000494:pharmacology; D005978:Glutathione / Q000378:metabolism; D013431:Sulfates / Q000378:metabolism*; D013460:Sulfur Isotopes; D013997:Time Factors
chemical_list: D000227:Adenine Nucleotides; D002247:Carbon Isotopes; D013431:Sulfates; D013460:Sulfur Isotopes; D005978:Glutathione; D003545:Cysteine; D005033:Ethylmaleimide