Iodine incorporated in cell constituents during sensitization to radiation by iodoacetic acid.
Iodine atoms are incorporated in bacterial membrane proteins when cells are irradiated in the presence of iodoacetic acid labeled with iodine-131. Such atoms are produced on reaction of iodoacetic acid with the gamma ray-induced hydroxyl radicals in the surrounding medium.
D001426:Bacterial Proteins / Q000096:biosynthesis*; D002462:Cell Membrane / Q000378:metabolism*; D003851:Deoxyribonucleases; D004926:Escherichia coli / Q000166:cytology / Q000378:metabolism* / Q000528:radiation effects; D000431:Ethanol; D005609:Free Radicals; D007455:Iodine / Q000378:metabolism*; D007456:Iodine Isotopes; D007461:Iodoacetates / Q000494:pharmacology*; D011830:Radiation Effects; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D011854:Radiochemistry; D012260:Ribonucleases; D014238:Trichloroacetic Acid
D001426:Bacterial Proteins; D005609:Free Radicals; D007456:Iodine Isotopes; D007461:Iodoacetates; D011838:Radiation-Sensitizing Agents; D000431:Ethanol; D014238:Trichloroacetic Acid; D007455:Iodine; D003851:Deoxyribonucleases; D012260:Ribonucleases