Recombination-deficient mutant of Salmonella typhimurium.
A recombination-deficient (Rec(-)) ultraviolet-sensitive mutant of Salmonella typhimurium was isolated. The mutant grows more slowly than the wild-type strain and degrades its deoxyribonucleic acid extensively both during normal growth and after ultraviolet irradiation. Evidence is presented that a growing Rec(-) population consists of two types of cells, one which can divide and one which cannot.
D002499:Centrifugation, Density Gradient; D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000378:metabolism; D009154:Mutation; D011995:Recombination, Genetic; D012483:Salmonella Phages; D012486:Salmonella typhimurium / Q000528:radiation effects; D014466:Ultraviolet Rays
D004269:DNA, Bacterial