Mitotic division in pancreatic beta cells.
Successful expansion of the islet cell mass occurs in genetically diabetic mice (C57 Bl/Ks-dbdb) following a period of dietary restriction, in the absence of a population of precursor cells. Differentiated cells that synthesize insulin retain the capability of undergoing mitotic division.
D000818:Animals; D003920:Diabetes Mellitus; D004032:Diet; D007328:Insulin / Q000096:biosynthesis; D007515:Islets of Langerhans / Q000166:cytology* / Q000473:pathology; D051379:Mice; D008854:Microscopy, Electron; D008938:Mitosis
D007328:Insulin