title: Iodine incorporated in cell constituents during sensitization to radiation by iodoacetic acid.
abstract: Iodine atoms are incorporated in bacterial membrane proteins when cells are irradiated in the presence of iodoacetic acid labeled with iodine-131. Such atoms are produced on reaction of iodoacetic acid with the gamma ray-induced hydroxyl radicals in the surrounding medium.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D002462:Cell Membrane / Q000378:metabolism*; D003851:Deoxyribonucleases; D004926:Escherichia coli / Q000166:cytology / Q000378:metabolism* / Q000528:radiation effects; D000431:Ethanol; D005609:Free Radicals; D007455:Iodine / Q000378:metabolism*; D007456:Iodine Isotopes; D007461:Iodoacetates / Q000494:pharmacology*; D011830:Radiation Effects; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D011854:Radiochemistry; D012260:Ribonucleases; D014238:Trichloroacetic Acid
chemical_list: D001426:Bacterial Proteins; D005609:Free Radicals; D007456:Iodine Isotopes; D007461:Iodoacetates; D011838:Radiation-Sensitizing Agents; D000431:Ethanol; D014238:Trichloroacetic Acid; D007455:Iodine; D003851:Deoxyribonucleases; D012260:Ribonucleases