title: Large abnormal acrocentric chromosome associated with human malignancies. Possible mechanism of establishing clone of cells.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002999:Clone Cells / Q000254:growth & development*; D003036:Cobalt Isotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000235:genetics; D007951:Leukemia, Myeloid / Q000235:genetics; D007962:Leukocytes / Q000166:cytology; D008198:Lymph Nodes / Q000166:cytology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000235:genetics; D008297:Male; D008545:Melanoma / Q000235:genetics; D008875:Middle Aged; D009369:Neoplasms / Q000235:genetics* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D003036:Cobalt Isotopes