Serotonin: release in the forebrain by stimulation of midbrain raphé.
Electrical stimulation of the midbrain raphé, an area in which neuronal perikarya containing serotonin are aggregated, produces an increase in 5-hydroxyindoleacetic acid and a decrease in serotonin in the forebrain. These changes indicate that serotonin in the brain can be released via a specific neural pathway, namely, the system of axons projecting into the forebrain from serotonin-containing neurons in the midbrain raphé.
D000818:Animals; D004558:Electric Stimulation; D006897:Hydroxyindoleacetic Acid / Q000032:analysis / Q000378:metabolism*; D008636:Mesencephalon / Q000032:analysis / Q000502:physiology*; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D012701:Serotonin / Q000032:analysis / Q000378:metabolism*; D013238:Stereotaxic Techniques; D013687:Telencephalon / Q000378:metabolism*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid