Mechanism and prevention of fixed high vascular resistance in autografted and allografted lungs.
The fixed vascular resistance observed in tranisplanted Ilunlgs and attriblted to denervation can be avoided by angioplastic wideniing of the pulmonary artery anastotosis. With distenisible arterial anrastomoses, aultografted an, d allografted Ilunzgs vasodilate niormzally with inicreased flow and cani sutstaini dogs whose contralateral pulmonary artery is ligated imumediately after lutng transplanitation.
D000818:Animals; D003714:Denervation / Q000009:adverse effects; D004285:Dogs; D016040:Lung Transplantation; D011651:Pulmonary Artery / Q000502:physiology / Q000601:surgery; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D014655:Vascular Resistance