Hypothalamic stimulation of growth hormone secretion.
Stimulation of the ventromedial hypothalamic nucleus in rats resulted in increased plasma growth hormone levels within 5 minutes, as measured by radioimmunoassay. Stimulation of the cerebral cortex was without effect. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion.
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D004558:Electric Stimulation; D005260:Female; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007031:Hypothalamus / Q000502:physiology*; D010906:Pituitary Hormone-Releasing Hormones / Q000502:physiology*; D011863:Radioimmunoassay; D051381:Rats
D010906:Pituitary Hormone-Releasing Hormones; D013006:Growth Hormone