Falciparum malaria transmissible from monkey to man by mosquito bite.
Anopheles freeborni mosquitoes were infected by feeding on a New World monkey, Aotus trivirgatus, infected with the Malayan IV strain of Plasmodium falciparum. After a normal incubation period, the infection was passed to a human volunteer through the bites of these mosquitoes, demonstrating for the first time the practicability of using a simian host as a donor for the infection of mosquitoes with this species of human malarial parasites.
D000818:Animals; D000852:Anopheles; D006801:Humans; D007299:Insect Bites and Stings; D007303:Insect Vectors; D008288:Malaria; D008992:Monkey Diseases; D010963:Plasmodium falciparum; D015047:Zoonoses