Comparison of piperazine and tetramisole in the treatment of ascariasis.
Tetramisole, a new synthetic anthelmintic, was compared with piperazine in the treatment of ascariasis in African children. Of 100 children receiving tetramisole 94 were cured, and of 100 given piperazine 85 were cured (0.05>P>0.02). Tetramisole was free of side-effects.
D000871:Anthelmintics / Q000627:therapeutic use*; D001196:Ascariasis / Q000188:drug therapy*; D002400:Cathartics; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005215:Fasting; D005243:Feces; D006801:Humans; D010879:Piperazines / Q000627:therapeutic use*; D013844:Thiazoles / Q000627:therapeutic use*
D000871:Anthelmintics; D002400:Cathartics; D010879:Piperazines; D013844:Thiazoles