2-Amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3, 4-thiadiazole: a new antimicrobial agent.
The title compound has been prepared and shown to be highly active against a wide variety of gram-positive and gram-negative bacteria in mice and chicks, as well as against a number of parasitic infections in rodents.
D000562:Amebiasis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D002645:Chickens; D003048:Coccidiosis; D004405:Dysentery, Bacillary; D004754:Enterobacter; D004927:Escherichia coli Infections; D005260:Female; D007093:Imidazoles / Q000138:chemical synthesis / Q000494:pharmacology*; D007239:Infections; D007710:Klebsiella Infections; D007896:Leishmaniasis; D009682:Magnetic Resonance Spectroscopy; D008585:Meningitis, Meningococcal; D051379:Mice; D010326:Pasteurella Infections; D012481:Salmonella Infections, Animal; D013210:Staphylococcus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013844:Thiazoles / Q000138:chemical synthesis / Q000494:pharmacology*; D014247:Trichomonas Vaginitis; D014352:Trypanosomiasis
D000900:Anti-Bacterial Agents; D007093:Imidazoles; D013844:Thiazoles