Survey of the eventual diagnosis in 600 cases referred for a second histological opinion after an initial biopsy diagnosis of Hodgkin's disease.
In a series of 600 cases of lymphadenopathy in which an initial histological diagnosis of Hodgkin's disease was reviewed in a reference laboratory this interpretation was confirmed in 317 cases (53%). In the 283 other cases the diagnosis of Hodgkin's disease was considered to be mistaken. The condition most frequently confused with Hodgkin's disease was chronic non-specific lymphadenitis. Reticulum cell sarcoma, metastatic tumours, infectious mononucleosis, dermatopathic lymphadenopathy, toxoplasmosis, and early sarcoidosis were also notably frequent among the conditions mistaken for Hodgkin's disease.
D001706:Biopsy; D003937:Diagnosis, Differential; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology*; D008199:Lymphadenitis / Q000175:diagnosis; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis; D009362:Neoplasm Metastasis / Q000175:diagnosis; D012507:Sarcoidosis / Q000175:diagnosis; D012871:Skin Diseases / Q000175:diagnosis; D014123:Toxoplasmosis / Q000175:diagnosis