Lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice.
Newborn mice infected with lymphocytic choriomeningitis virus are not immunologically tolerant to the agent but, rather, appear to make antibody to the virus. This antibody was detectable only in the kidneys, where presumably it had been deposited in the glomeruli in the form of complexes of antibody, virus, and complement.
D000818:Animals; D000917:Antibody Formation; D003168:Complement Fixation Tests; D005455:Fluorescent Antibody Technique; D007108:Immune Tolerance; D007678:Kidney Glomerulus / Q000473:pathology; D008216:Lymphocytic Choriomeningitis / Q000276:immunology*; D051379:Mice