The mechanism of alkylation of DNA by 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MIC), a metabolite of DIC (NSC-45388). Non-involvement of diazomethane.
D000818:Animals; D001665:Binding Sites; D002417:Cattle; D003460:Crystallization; D004247:DNA; D003903:Deuterium; D003978:Diazomethane; D004355:Drug Stability; D006147:Guanine; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008745:Methylation; D008968:Molecular Conformation; D009690:Nucleic Acid Conformation; D010795:Phthalic Acids; D012995:Solubility; D013950:Thymus Gland; D014226:Triazenes
D007093:Imidazoles; D010795:Phthalic Acids; D014226:Triazenes; D006147:Guanine; D003978:Diazomethane; D004247:DNA; D003903:Deuterium