title: Neonatal cardiac distress. A practical approach to recognition, diagnosis, and management.
abstract: The death rate among neonates with cardiovascular disease is 50 percent during the first six months, with the majority dying during the first month. With early diagnosis most of these babies could be saved. In approaching the diagnosis of cardiac distress in the newborn, it is important to remember that the types of cardiovascular disease which cause symptoms and death early in life are quite different from those in older children. Lesions such as hypoplasia of the left heart, transposition of the great arteries, endocardial fibroelastosis, pulmonary atresia, mitral atresia, tricuspid atresia and truncus arteriosus are common, not rare, causes of cardiac distress in the newborn.A classification of neonatal cardiovascular diseases into seven pathophysiological groups is presented as a basis for an effective, practical approach to the differential diagnosis of the potentially lethal lesions. This approach is simplified further since over 90 percent of babies with cardiac distress have one of three lesions: (1) Large left-to-right shunt (characterized by the presence of massive plethora on the chest roentgenogram), (2) Large right-to-left shunt (association with intense cyanosis) or (3) Severe obstruction (including hypoplasia of the left heart, which is the most common cause of death due to cardiac distress during the first week of life).
mesh_terms: D001022:Aortic Valve Insufficiency; D001145:Arrhythmias, Cardiac; D003914:Dextrocardia; D004562:Electrocardiography; D004695:Endocardial Fibroelastosis / Q000175:diagnosis; D006327:Heart Block; D006330:Heart Defects, Congenital; D006801:Humans; D007231:Infant, Newborn; D009205:Myocarditis; D014188:Transposition of Great Vessels