Selection of araB and araC mutants of Escherichia coli B-r by resistance to ribitol.
The growth of strain araC(c)67, which produces the enzymes of the ara operon constitutively, is inhibited by the addition of ribitol. Isolation of strains resistant to ribitol yields mutants of either the araB or araC genes. A model to account for the inhibition by ribitol is discussed.
D000438:Alcohols / Q000494:pharmacology; D000483:Alleles; D001089:Arabinose / Q000494:pharmacology; D002241:Carbohydrates / Q000494:pharmacology*; D002364:Caseins; D003124:Colorimetry; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development / Q000302:isolation & purification; D005643:Fucose / Q000494:pharmacology; D005796:Genes; D005816:Genetic Complementation Test; D005827:Genetics, Microbial; D009154:Mutation; D010770:Phosphotransferases / Q000378:metabolism; D013778:Tetrazolium Salts
D000438:Alcohols; D002241:Carbohydrates; D002364:Caseins; D003470:Culture Media; D013778:Tetrazolium Salts; D005643:Fucose; D001089:Arabinose; D010770:Phosphotransferases