Genetic analysis of recombination-deficient mutants of Escherichia coli K-12 carrying rec mutations cotransducible with thyA.
The rec mutations carried by 20 strains of Escherichia coli K-12 which are defective in genetic recombination and sensitive to ultraviolet light and X rays, and whose lambda lysogens show spontaneous phage production, have been mapped near thyA. In 15 of the strains, the rec mutation fails to complement recB21 but complements rec-22. The other five strains carry a rec mutation which complements recB21 but not rec-22. These mutations map closer to thyA than those which fail to complement recB21. They therefore appear to be defective in a different recombination gene, denoted recC. The order of recB and recC on the linkage map of E. coli K-12 is thyA-recC-recB-argA.
D000483:Alleles; D002874:Chromosome Mapping; D004926:Escherichia coli / Q000528:radiation effects; D006579:Heterozygote; D009154:Mutation; D010641:Phenotype; D011995:Recombination, Genetic; D014161:Transduction, Genetic; D014466:Ultraviolet Rays