Role of erythrocytes in the acute platelet response to operation.
A marked increase in platelet adhesiveness was shown to occur within four hours of operation. Postoperative red cells produced greater adhesiveness in platelets from a common pool than did preoperative red cells. A greater increase in platelet adhesiveness was observed following operation with the whole blood technique than when exogenous adenosine diphosphate was added to platelet-rich plasma. Release of adenosine diphosphate from red cells so facilitated may contribute to the acute platelet-adhesiveness response to operation.
D000227:Adenine Nucleotides / Q000378:metabolism / Q000494:pharmacology; D001772:Blood Cell Count; D001792:Blood Platelets / Q000502:physiology*; D004912:Erythrocytes / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008858:Microscopy, Phase-Contrast; D013514:Surgical Procedures, Operative
D000227:Adenine Nucleotides