title: Escherichia coli mutants defective in chemotaxis toward specific chemicals.
abstract: Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific "chemoreceptors."
mesh_terms: D002633:Chemotaxis; D004926:Escherichia coli; D005690:Galactose / Q000378:metabolism; D005827:Genetics, Microbial; D005947:Glucose / Q000378:metabolism; D008954:Models, Biological; D009154:Mutation; D010101:Oxygen Consumption; D011955:Receptors, Drug; D012266:Ribose / Q000378:metabolism; D012694:Serine / Q000378:metabolism
chemical_list: D011955:Receptors, Drug; D012694:Serine; D012266:Ribose; D005947:Glucose; D005690:Galactose