title: Possible mechanisms in development of tolerance.
mesh_terms: D000222:Adaptation, Physiological; D000700:Analgesics / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D002386:Cataract / Q000139:chemically induced; D002395:Catecholamines / Q000378:metabolism; D003513:Cycloheximide / Q000494:pharmacology; D004361:Drug Tolerance; D006706:Homeostasis; D006801:Humans; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D051379:Mice; D009020:Morphine / Q000009:adverse effects; D009021:Morphine Dependence; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D011955:Receptors, Drug; D013375:Substance Withdrawal Syndrome
chemical_list: D000700:Analgesics; D002395:Catecholamines; D011955:Receptors, Drug; D009020:Morphine; D003513:Cycloheximide; D009638:Norepinephrine