Imported malaria in the United Kingdom.
Over 2,000 cases of imported malaria have been confirmed by blood examination. Ninety percent. of cases from tropical Africa were infected with P. falciparum. Most of the patients were Caucasians and had primary infections. All developed fever within a month after arrival and most of them within two weeks of arrival. In some patients malaria parasites were seen in routine blood films.Developing forms of P. falciparum were always present in the peripheral blood of patients suffering from a primary attack which was not diagnosed or treated until a week or more after the onset of fever.All deaths investigated were caused by P. falciparum and were primary infections.In not one of the P. falciparum infections did the victim continue taking prophylactic drugs for more than a few days after leaving the endemic area. Had drugs been continued for one month probably not a single overt case of P. falciparum would have occurred.A primary attack of P. falciparum malaria is seldom, if ever, classical in that the fever is never tertian and may resemble clinically many other diseases.Children in boarding-schools returning from the tropics should be supplied with prophylactic tablets and instructions to the matron. If there is an epidemic of a fever any students who have recently returned from the tropics should have a blood film examined for malaria.The risk of contracting malaria among drug addicts is considerable, especially with P. falciparum.
D000401:Aircraft; D000962:Antimalarials / Q000627:therapeutic use; D002648:Child; D003140:Communicable Disease Control; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008288:Malaria / Q000097:blood / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D008297:Male; D010963:Plasmodium falciparum / Q000302:isolation & purification; D019966:Substance-Related Disorders; D065227:Transfusion Reaction; D014195:Travel; D006113:United Kingdom
D000962:Antimalarials