Altered ribosomal protein in streptomycin-dependent Escherichia coli.
We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altered in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribosomes resistant to streptomycin.
D001426:Bacterial Proteins / Q000302:isolation & purification*; D002247:Carbon Isotopes; D004352:Drug Resistance, Microbial; D004926:Escherichia coli; D010649:Phenylalanine / Q000378:metabolism; D012270:Ribosomes; D013307:Streptomycin / Q000494:pharmacology*
D001426:Bacterial Proteins; D002247:Carbon Isotopes; D010649:Phenylalanine; D013307:Streptomycin