Effect of anti-inflammatory drug therapy on clearance of 133-Xe from knee joints of patients with rheumatoid arthritis.
The degree of joint inflammation in 13 patients with rheumatoid arthritis, as measured by clinical indices, was reduced by both sodium salicylate and indomethacin. The clearance rate of (133)Xe was reduced by indomethacin alone, and showed no correlation with the clinical features.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D007249:Inflammation; D007270:Injections, Intra-Articular; D007717:Knee / Q000098:blood supply*; D010919:Placebos; D011868:Radioisotopes; D012980:Sodium Salicylate / Q000627:therapeutic use*; D014978:Xenon
D010919:Placebos; D011868:Radioisotopes; D014978:Xenon; D012980:Sodium Salicylate; D007213:Indomethacin