title: A T4-induced endonuclease which attacks T4 DNA.
abstract: A DNA endonucleolytic activity that introduces single-stranded breaks into native T4 DNA is found in T4-infected E. coli. This endonuclease attacks other double-stranded, but not single-stranded, DNA. Experiments with ultraviolet-irradiated phages and amber mutants indicate that the enzyme is made beginning about five minutes after infection at 37 degrees C.
mesh_terms: D002499:Centrifugation, Density Gradient; D003090:Coliphages / Q000378:metabolism* / Q000528:radiation effects; D004279:DNA, Viral / Q000378:metabolism*; D003851:Deoxyribonucleases / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology*; D005809:Genes, Regulator; D005964:Glucosyltransferases / Q000096:biosynthesis; D011831:Radiation Genetics; D014316:Tritium; D014466:Ultraviolet Rays
chemical_list: D004279:DNA, Viral; D014316:Tritium; D005964:Glucosyltransferases; D003851:Deoxyribonucleases