title: Visualization of bacterial genes in action.
abstract: The morphology of active structural and putative ribosomal RNA genes was observed by electron microscopy after lysis of fragile Escherichia coli cells. Conclusions drawn are: most of the chromosome is not genetically active at any one instant; translation is completely coupled with transcription; the 16S and 23S ribosomal RNA cistrons occur in tandem, in regions which are widely spaced on the chromosome.
mesh_terms: D002876:Chromosomes, Bacterial; D004926:Escherichia coli / Q000166:cytology*; D005796:Genes; D005815:Genetic Code; D005827:Genetics, Microbial; D006824:Hybridization, Genetic; D008854:Microscopy, Electron; D008967:Molecular Biology; D012316:RNA Nucleotidyltransferases; D012329:RNA, Bacterial / Q000096:biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism
chemical_list: D012329:RNA, Bacterial; D012333:RNA, Messenger; D012316:RNA Nucleotidyltransferases