The in vivo effect of folinic acid (citrovorum factor) on the potentiation of the antibacterial activity of sulfisoxazole by trimethoprim.
D000818:Animals; D004357:Drug Synergism; D004927:Escherichia coli Infections / Q000188:drug therapy; D005492:Folic Acid / Q000378:metabolism; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D002955:Leucovorin / Q000494:pharmacology*; D051379:Mice; D008954:Models, Biological; D011008:Pneumococcal Infections / Q000188:drug therapy; D011512:Proteus Infections / Q000188:drug therapy; D011743:Pyrimidines / Q000494:pharmacology*; D012480:Salmonella Infections / Q000188:drug therapy; D013290:Streptococcal Infections / Q000188:drug therapy; D013444:Sulfisoxazole / Q000494:pharmacology*
D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013444:Sulfisoxazole; D005492:Folic Acid; D002955:Leucovorin