Chikungunya virus infection of cell monolayers by cell-to-cell and extracellular transmission.
Both cell-to-cell and extracellular transmission of chikungunya virus infection was demonstrated in BHK21/C13 cell monolayers. The mode of virus infection may depend on the cell line. Virus transmission in L-929 and guinea pig lung cell lines was extracellular.
D000818:Animals; D002417:Cattle; D002460:Cell Line; D002646:Chikungunya virus; D006224:Cricetinae; D046508:Culture Techniques; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D007668:Kidney; D008168:Lung; D051379:Mice