Effect of propranolol on exercise tolerance of patients with atrial fibrillation.
Six patients with atrial fibrillation who were taking digitalis were exercised before and after 30 mg. of propranolol twice daily. Though there was a lower pulse rate at rest and on exercise in all patients, three suffered deterioration of exercise tolerance. It is concluded that propranolol does not improve the exercise tolerance of patients with atrial fibrillation whose resting ventricular rate is controlled with digitalis.
D000328:Adult; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000503:physiopathology*; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004071:Digitalis Glycosides / Q000627:therapeutic use; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D010919:Placebos; D011433:Propranolol / Q000494:pharmacology*
D004071:Digitalis Glycosides; D010919:Placebos; D011433:Propranolol