title: Ligand-induced maturation of threonine deaminase.
abstract: The dimeric intermediate substructures of threonine deaminase, which are obtained by alkaline dialysis of the native tetrameric enzyme, are inactive after reassembly unless they are subsequently exposed to maturation-inducing ligands for which the enzyme possesses stereospecific binding sites. The binding of the ligands at these sites precedes the full maturation of the enzyme.
mesh_terms: D001665:Binding Sites; D002850:Chromatography, Gel; D003956:Dialysis; D004789:Enzyme Activation; D006836:Hydro-Lyases / Q000032:analysis*; D012486:Salmonella typhimurium / Q000201:enzymology*; D013912:Threonine / Q000378:metabolism*
chemical_list: D013912:Threonine; D006836:Hydro-Lyases