Studies concerning the mechanism of action of antimalarial drugs. Inhibition of the incorporation of adenosine-8-3H into nucleic acids of Plasmodium berghei.
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D001345:Autoradiography; D002738:Chloroquine / Q000494:pharmacology; D004254:DNA Nucleotidyltransferases / Q000494:pharmacology; D004261:DNA Replication / Q000187:drug effects*; D004926:Escherichia coli; D008297:Male; D008722:Methods; D009705:Nucleosides / Q000378:metabolism*; D010617:Phenanthridines / Q000494:pharmacology; D010961:Plasmodium / Q000187:drug effects*; D011796:Quinacrine / Q000494:pharmacology; D011803:Quinine / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis*; D012316:RNA Nucleotidyltransferases / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014316:Tritium
D000962:Antimalarials; D009705:Nucleosides; D010617:Phenanthridines; D014316:Tritium; D012313:RNA; D002738:Chloroquine; D011803:Quinine; D004254:DNA Nucleotidyltransferases; D012316:RNA Nucleotidyltransferases; D011796:Quinacrine