title: Marihuana and temporal disintegration.
abstract: High oral doses of marihuana extract, calibrated for content of 1 (-)-Delta(1)-tetrahydrocannabinol, significantly impaired the serial coordination of cognitive operations during a task that required sequential adjustments in reaching a goal. This disintegration of sequential thought is related to impaired immediate memory.
mesh_terms: D000328:Adult; D002188:Cannabis / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects*; D010919:Placebos; D013998:Time Perception / Q000187:drug effects*
chemical_list: D010919:Placebos