title: Irreversible inactivation of Escherichia coli alkaline phosphatase with active site directed alkylating reagents.
mesh_terms: D000085:Acetates / Q000494:pharmacology; D000469:Alkaline Phosphatase / Q000032:analysis / Q000037:antagonists & inhibitors*; D000477:Alkylating Agents / Q000494:pharmacology*; D003864:Depression, Chemical; D004926:Escherichia coli / Q000201:enzymology; D006639:Histidine; D006863:Hydrogen-Ion Concentration; D007531:Isoflurophate / Q000494:pharmacology; D007700:Kinetics; D010710:Phosphates / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000085:Acetates; D000477:Alkylating Agents; D010710:Phosphates; D007531:Isoflurophate; D006639:Histidine; D000469:Alkaline Phosphatase