title: Virus of the 1918 influenza pandemic era: new evidence about its antigenic character.
abstract: In serums of unusually isolated Pacific islanders whose only exposure to influenza occurred during the era of the 1918 pandemic the residual neutralizing antibody was greatest to the PR/8 and BH strains of human type A influenza virus, significantly lower to swine influenza virus, and absent to equine or later human type A virus strains. The pandemic virus was thus antigenically closer to human type A strains isolated during the middle 1930's than to other known influenza virus types.
mesh_terms: D000818:Animals; D000941:Antigens / Q000145:classification*; D004196:Disease Outbreaks / Q000266:history*; D049673:History, 20th Century; D006736:Horses; D006801:Humans; D007106:Immune Sera / Q000145:classification; D007251:Influenza, Human / Q000266:history*; D008849:Micronesia; D009500:Neutralization Tests; D009975:Orthomyxoviridae / Q000276:immunology*; D013552:Swine
chemical_list: D000941:Antigens; D007106:Immune Sera