Fitness of an Escherichia coli mutator gene.
Competition experiments between Escherichia coli mutT1 and mut(+) populations show that the mutator gene confers selective advantage on the strain that carries it. The observed increase in fitness varies, with an average increase in mutator growth rate of 1.4 percent when mutator and wild-type strains are grown together in chemostats.
D004261:DNA Replication; D004926:Escherichia coli / Q000378:metabolism*; D005796:Genes; D005827:Genetics, Microbial; D007785:Lactose / Q000378:metabolism; D009154:Mutation; D012641:Selection, Genetic
D007785:Lactose