title: Comparative biochemistry of dihydrofolate reductase.
mesh_terms: D000818:Animals; D001001:Anura; D001669:Biochemical Phenomena; D001671:Biochemistry; D004926:Escherichia coli / Q000201:enzymology; D005399:Fishes; D005493:Folic Acid Antagonists; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008288:Malaria / Q000201:enzymology; D008727:Methotrexate / Q000494:pharmacology; D008121:Nephropidae / Q000201:enzymology; D011514:Proteus vulgaris / Q000201:enzymology; D011725:Pyridines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D011799:Quinazolines / Q000494:pharmacology; D011894:Rana pipiens; D051381:Rats; D013210:Staphylococcus / Q000201:enzymology; D013621:Taenia / Q000201:enzymology; D013762:Tetrahydrofolate Dehydrogenase; D014227:Triazines / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D014426:Turtles
chemical_list: D005493:Folic Acid Antagonists; D011725:Pyridines; D011743:Pyrimidines; D011799:Quinazolines; D014227:Triazines; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate