Inhibition by phenylalanine of thiazole biosynthesis in Escherichia coli.
Phenylalanine inhibited thiazole biosynthesis in a thiamine-regulatory mutant of Escherichia coli, and the inhibition was overcome by tyrosine.
D003864:Depression, Chemical; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D005827:Genetics, Microbial; D009154:Mutation; D010649:Phenylalanine / Q000494:pharmacology*; D012765:Shikimic Acid / Q000494:pharmacology; D013831:Thiamine / Q000096:biosynthesis; D013844:Thiazoles / Q000096:biosynthesis*; D014364:Tryptophan / Q000494:pharmacology; D014443:Tyrosine / Q000494:pharmacology
D013844:Thiazoles; D012765:Shikimic Acid; D014443:Tyrosine; D010649:Phenylalanine; D014364:Tryptophan; D013831:Thiamine