title: Ribosome-catalyzed polyester formation.
abstract: Deamination of phenylalanyl-transfer RNA with nitrous acid yields the alpha-hydroxyacyl analog, phenyllactyl-transfer RNA. When this is incubated in a protein-synthesizing system directed by polyuridylic acid, it yields an acid-precipitable, alkali-labile polyester of phenyllactic acid.
mesh_terms: D001711:Biotransformation; D002498:Centrifugation; D011232:Chemical Precipitation; D002845:Chromatography; D003641:Deamination; D004926:Escherichia coli / Q000378:metabolism; D004952:Esters; D007773:Lactates / Q000096:biosynthesis*; D009573:Nitrites; D010452:Peptide Biosynthesis; D010649:Phenylalanine; D011108:Polymers / Q000096:biosynthesis*; D011119:Polynucleotides / Q000378:metabolism*; D012329:RNA, Bacterial / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism*; D012270:Ribosomes / Q000201:enzymology*; D014166:Transferases / Q000378:metabolism*; D014500:Uracil Nucleotides
chemical_list: D004952:Esters; D007773:Lactates; D009573:Nitrites; D011108:Polymers; D011119:Polynucleotides; D012329:RNA, Bacterial; D014500:Uracil Nucleotides; D010649:Phenylalanine; D012343:RNA, Transfer; D014166:Transferases