title: [Relationship between pharmacological effect and chemical structure in a series of bis-quaternary compounds of ethylene and hexamethylene diamine derivatives].
mesh_terms: D000109:Acetylcholine / Q000097:blood; D000315:Adrenalectomy; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects / Q000302:isolation & purification; D001419:Bacteria / Q000187:drug effects*; D002540:Cerebral Cortex / Q000187:drug effects; D055598:Chemical Phenomena; D002623:Chemistry Techniques, Analytical; D002627:Chemistry, Physical; D002712:Chlorides / Q000652:urine; D002802:Cholinesterases / Q000097:blood; D003864:Depression, Chemical; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000187:drug effects; D005029:Ethylenediamines / Q000008:administration & dosage / Q000627:therapeutic use / Q000633:toxicity; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D051379:Mice; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D011654:Pulmonary Edema / Q000517:prevention & control; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D051381:Rats; D012226:Rhinoscleroma / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality / Q000517:prevention & control; D013210:Staphylococcus / Q000187:drug effects; D013268:Stimulation, Chemical; D013291:Streptococcus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D002712:Chlorides; D005029:Ethylenediamines; D006993:Hypnotics and Sedatives; D000644:Quaternary Ammonium Compounds; D002802:Cholinesterases; D000109:Acetylcholine; D010433:Pentylenetetrazole
vernacular_title: Zavisimost' farmakologicheskogo deĭstviia ot khimicheskogo stroeniia v riadu bis-chetvertichnykh soedineniĭ proizvodnykh etylen- i geksametilendiamina.