title: Hyposensitization with Dermatophagoides pteronyssinus antigen: trial in asthma induced by house dust.
abstract: A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for a year but six relapsed. These results contrasted with the generally unfavourable course of the patients treated with the extract of human skin scales. Asthma due to house-dust allergy may be substantially improved by hyposensitization with D. pteronyssinus extract.
mesh_terms: D000941:Antigens; D001249:Asthma / Q000628:therapy*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003888:Desensitization, Immunologic; D004391:Dust; D006801:Humans; D007279:Injections, Subcutaneous; D008925:Mites / Q000276:immunology*; D012867:Skin / Q000276:immunology; D012882:Skin Tests; D014867:Water
chemical_list: D000941:Antigens; D004391:Dust; D014867:Water