title: Potassium transport loci in Escherichia coli K-12.
abstract: Mutants of Escherichia coli K-12 requiring considerably elevated concentrations of potassium for growth are readily obtained as double mutants combining a kdp mutation with a mutation in one or more of five other loci. These loci are referred to as trk, for transport of K, because these mutations result in alterations in K transport. The kdp mutation is essential in the isolation and identification of this type of mutant; in a Kdp(+) strain, the presence of a trk mutation does not prevent growth of the strain in media containing very low concentrations of K. The trk loci are widely scattered over the E. coli chromosome; none of them is very near any other trk locus or near the kdp genes.
mesh_terms: D000225:Adenine / Q000494:pharmacology; D001692:Biological Transport; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D003433:Crosses, Genetic; D003470:Culture Media; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism* / Q000528:radiation effects; D005796:Genes; D005816:Genetic Complementation Test; D005827:Genetics, Microbial; D006863:Hydrogen-Ion Concentration; D009153:Mutagens; D009154:Mutation; D011188:Potassium / Q000378:metabolism*; D011995:Recombination, Genetic; D014161:Transduction, Genetic; D014466:Ultraviolet Rays
chemical_list: D003470:Culture Media; D009153:Mutagens; D000225:Adenine; D011188:Potassium