Effect of rifampin on the development of ribonucleic acid bacteriophage Q .
The drug rifampin, when added at the time of infection, inhibits synthesis of the phage Qbeta. Both viral ribonucleic acids and viral proteins are made in nearly the same amount as in the absence of rifampin, but the rate of assembly into phage particles is low.
D000936:Antigen-Antibody Complex; D002247:Carbon Isotopes; D003090:Coliphages / Q000187:drug effects / Q000254:growth & development* / Q000276:immunology / Q000378:metabolism; D004352:Drug Resistance, Microbial; D004589:Electrophoresis, Disc; D004926:Escherichia coli / Q000187:drug effects / Q000276:immunology; D005827:Genetics, Microbial; D008239:Lysine / Q000378:metabolism; D009154:Mutation; D012367:RNA, Viral / Q000096:biosynthesis; D012293:Rifampin / Q000494:pharmacology*; D013997:Time Factors; D014316:Tritium; D014498:Uracil / Q000378:metabolism; D014764:Viral Proteins / Q000096:biosynthesis*
D000936:Antigen-Antibody Complex; D002247:Carbon Isotopes; D012367:RNA, Viral; D014764:Viral Proteins; D014316:Tritium; D014498:Uracil; D008239:Lysine; D012293:Rifampin