title: Nalidixic acd-resistant mutants of Escherichia coli deficient in isocitrate dehydrogenase.
abstract: icd Mutants of Escherichia coli K-12, selected for their resistance to nalidixic acid, are deficient in isocitrate dehydrogenase.
mesh_terms: D002952:Citric Acid Cycle; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism; D005827:Genetics, Microbial; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005971:Glutamates / Q000096:biosynthesis; D007521:Isocitrate Dehydrogenase / Q000378:metabolism*; D008190:Lyases / Q000378:metabolism; D009154:Mutation; D009268:Nalidixic Acid / Q000494:pharmacology*
chemical_list: D003470:Culture Media; D005971:Glutamates; D009268:Nalidixic Acid; D007521:Isocitrate Dehydrogenase; D005969:Glutamate Dehydrogenase; D008190:Lyases