title: Interconvertible forms of Escherichia coli RNA polymerase.
abstract: Escherichia coli RNA polymerase exists in two different forms, one less active than the other under standard assay conditions. Conversion of the active to the inactive form requires ATP-Mg(++). The reverse, inactive to active enzyme conversion, requires Mg(++). Covalently bound adenylic acid residue(s) are contained in the inactive form.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D002247:Carbon Isotopes; D002852:Chromatography, Ion Exchange; D004789:Enzyme Activation; D004926:Escherichia coli / Q000201:enzymology*; D005809:Genes, Regulator; D008274:Magnesium / Q000378:metabolism; D010759:Phosphorus Isotopes; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D012329:RNA, Bacterial
chemical_list: D002247:Carbon Isotopes; D010759:Phosphorus Isotopes; D012329:RNA, Bacterial; D000255:Adenosine Triphosphate; D012316:RNA Nucleotidyltransferases; D008274:Magnesium