title: A temperature-sensitive thy mutant blocked in the synthesis of thymidylate synthetase.
mesh_terms: D002499:Centrifugation, Density Gradient; D055598:Chemical Phenomena; D002621:Chemistry; D002701:Chloramphenicol / Q000494:pharmacology; D003470:Culture Media; D003903:Deuterium; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology*; D005796:Genes; D005969:Glutamate Dehydrogenase / Q000096:biosynthesis; D008745:Methylation; D008780:Methyltransferases / Q000096:biosynthesis; D008954:Models, Biological; D009154:Mutation; D010452:Peptide Biosynthesis; D012270:Ribosomes / Q000378:metabolism; D012965:Sodium Chloride / Q000494:pharmacology; D013696:Temperature; D013942:Thymine Nucleotides / Q000096:biosynthesis; D013997:Time Factors; D014161:Transduction, Genetic; D014166:Transferases / Q000096:biosynthesis*; D014316:Tritium; D014500:Uracil Nucleotides
chemical_list: D003470:Culture Media; D013942:Thymine Nucleotides; D014500:Uracil Nucleotides; D014316:Tritium; D012965:Sodium Chloride; D002701:Chloramphenicol; D003903:Deuterium; D005969:Glutamate Dehydrogenase; D014166:Transferases; D008780:Methyltransferases