title: Increased resistance to several antibiotics by one mutation in an R-factor, R 1a.
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D004926:Escherichia coli / Q000187:drug effects*; D005796:Genes; D005827:Genetics, Microbial; D009154:Mutation; D010403:Penicillin Resistance; D010405:Penicillinase / Q000032:analysis; D013307:Streptomycin / Q000494:pharmacology; D013424:Sulfanilamides / Q000494:pharmacology; D013451:Sulfonic Acids / Q000494:pharmacology; D014161:Transduction, Genetic
chemical_list: D013424:Sulfanilamides; D013451:Sulfonic Acids; D002701:Chloramphenicol; D000667:Ampicillin; D010405:Penicillinase; D013307:Streptomycin