The supra-additive natriuretic effect addition of quinethazone or bendroflumethiazide during long-term treatment with furosemide and spironolactone. Permutation trial tests in patients with congestive heart failure.
D000328:Adult; D001539:Bendroflumethiazide / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D004231:Diuresis / Q000187:drug effects; D004357:Drug Synergism; D005665:Furosemide / Q000494:pharmacology*; D006333:Heart Failure / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007671:Kidney Concentrating Ability; D009318:Natriuresis / Q000187:drug effects*; D009994:Osmolar Concentration; D010919:Placebos; D013148:Spironolactone / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*
D010919:Placebos; D013449:Sulfonamides; D013148:Spironolactone; D001539:Bendroflumethiazide; D005665:Furosemide