title: Replication of bacteriophage phiX174 in a temperature-sensitive deoxyribonucleic acid host cell.
abstract: Bacteriophage phiX174 is unable to replicate in Escherichia coli t3 at the restrictive temperature. However, if progeny phage synthesis is initiated at the permissive temperature, it will continue after a shift to the restrictive temperature.
mesh_terms: D003090:Coliphages / Q000254:growth & development* / Q000302:isolation & purification; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004926:Escherichia coli / Q000254:growth & development / Q000378:metabolism*; D005827:Genetics, Microbial; D009154:Mutation; D013696:Temperature; D013941:Thymine / Q000378:metabolism; D014316:Tritium; D014779:Virus Replication
chemical_list: D004269:DNA, Bacterial; D014316:Tritium; D013941:Thymine