title: The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions.
abstract: The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1-12 as well as other nondefined specificities. Mixed leukocyte reactions were also studied in this series and the correlations between the mixed leukocyte reactions with skin graft survival times, individual HL-A specificities, and the number of incompatible HL-A alleles are reported. Comments concerning the interpretation and quantitation of the mixed leukocyte reactions are discussed.
mesh_terms: D000483:Alleles; D000941:Antigens; D006648:Histocompatibility; D006801:Humans; D007125:Immunogenetics; D007962:Leukocytes / Q000276:immunology*; D016038:Skin Transplantation; D013997:Time Factors
chemical_list: D000941:Antigens