Antigen-binding cells in normal mouse thymus.
The thymus of a normal adult mouse contains lymphocytic cells with a large number of antigen-binding receptors. Binding of the antigen by these cells is specific and can be inhibited by cross-reactive materials. It is possible that the interaction of thymocytes with antibody-forming precursor cells, required in the primary immune response to certain antigens, is mediated by these specific antigen-binding cells of the thymus.
D000818:Animals; D000941:Antigens; D001665:Binding Sites; D004926:Escherichia coli / Q000201:enzymology; D005455:Fluorescent Antibody Technique; D005470:Fluorometry; D005696:Galactosidases; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008856:Microscopy, Fluorescence; D013950:Thymus Gland / Q000166:cytology*
D000941:Antigens; D005696:Galactosidases