Enhancement of the phenylalanyl-oligonucleotide binding to the peptidyl recognition center of ribosomal peptidyltransferase and inhibition of the chloramphenicol binding to ribosomes.
D000217:Acyltransferases / Q000378:metabolism*; D000227:Adenine Nucleotides / Q000378:metabolism / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001665:Binding Sites; D002247:Carbon Isotopes; D002701:Chloramphenicol / Q000378:metabolism*; D003597:Cytosine Nucleotides / Q000378:metabolism / Q000494:pharmacology; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology; D007700:Kinetics; D010441:Peptide Chain Elongation, Translational; D010455:Peptides; D010649:Phenylalanine / Q000378:metabolism / Q000494:pharmacology; D011119:Polynucleotides / Q000378:metabolism / Q000494:pharmacology; D011691:Puromycin / Q000378:metabolism; D012270:Ribosomes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D014316:Tritium
D000227:Adenine Nucleotides; D000900:Anti-Bacterial Agents; D002247:Carbon Isotopes; D003597:Cytosine Nucleotides; D010455:Peptides; D011119:Polynucleotides; D014316:Tritium; D000431:Ethanol; D010649:Phenylalanine; D011691:Puromycin; D002701:Chloramphenicol; D000217:Acyltransferases