Transience of immune responses to tumour antigens in man.
By examining serial serum samples from patients undergoing surgical removal of malignant tumours an increased incidence of tumour-specific antibodies has been detected. Antibody responses to tumour neoantigens seem to be transient, and this is held to account for the rarity of detections where a single sample of serum is examined.
D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D000941:Antigens; D000951:Antigens, Neoplasm; D001943:Breast Neoplasms / Q000276:immunology / Q000601:surgery; D003110:Colonic Neoplasms / Q000276:immunology / Q000601:surgery; D003168:Complement Fixation Tests; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D009369:Neoplasms / Q000276:immunology*; D011233:Precipitin Tests; D012004:Rectal Neoplasms / Q000276:immunology / Q000601:surgery; D013274:Stomach Neoplasms / Q000276:immunology / Q000601:surgery
D000906:Antibodies; D000941:Antigens; D000951:Antigens, Neoplasm