Structure of the replicating DNA from bacteriophage T4.
At an early stage of replication, parental T4 DNA shows a loop structure often displaying two 3'-ended, single-stranded "whiskers", located in trans configuration at the branching-points. Several such loops have been observed within a single T4 molecule. Occasionally, reinitiation occurred in the middle of a loop, which suggests that the loop was growing in both directions.
D002499:Centrifugation, Density Gradient; D003090:Coliphages / Q000032:analysis*; D004261:DNA Replication; D004269:DNA, Bacterial / Q000032:analysis*; D003851:Deoxyribonucleases; D004926:Escherichia coli / Q000032:analysis*; D008854:Microscopy, Electron; D008961:Models, Structural; D009690:Nucleic Acid Conformation; D010759:Phosphorus Isotopes; D014316:Tritium
D004269:DNA, Bacterial; D010759:Phosphorus Isotopes; D014316:Tritium; D003851:Deoxyribonucleases