title: Immunofluorescence studies on the distribution of gastrin cells in different clinical states.
abstract: Examination of human gastric biopsies by an indirect immunofluorescence technique using antihuman gastrin confirms the variability in distribution and number of gastrin-secreting (G) cells (Solcia, Vassallo, and Capella, 1969) observed by morphological, cytochemical, and electron microscopical studies. In cases with presumed secondary hypersecretion a profound degree of G-cell hyperplasia is observed. Immunofluorescence with. antigastrin can provide valuable information on the state of the G cells in different physiological states, particularly if used in conjunction with other cytochemical techniques.
mesh_terms: D000328:Adult; D000818:Animals; D001706:Biopsy; D005260:Female; D005455:Fluorescent Antibody Technique; D005753:Gastric Mucosa / Q000166:cytology* / Q000276:immunology / Q000473:pathology; D005755:Gastrins / Q000378:metabolism*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D011817:Rabbits
chemical_list: D005755:Gastrins