title: The significance of properly designed pre-clinical studies in the clinical evaluation of new drugs.
mesh_terms: D000014:Abnormalities, Drug-Induced; D000818:Animals; D001702:Biopharmaceutics; D002626:Chemistry, Pharmaceutical; D002986:Clinical Trials as Topic; D006801:Humans; D007700:Kinetics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D010600:Pharmacology; D011485:Protein Binding
chemical_list: D004364:Pharmaceutical Preparations