An improved synthesis of diaveridine, trimethoprim, and closely related 2,4-diaminopyrimidines.
D000284:Administration, Oral; D000818:Animals; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D004357:Drug Synergism; D004927:Escherichia coli Infections / Q000188:drug therapy; D007710:Klebsiella Infections / Q000188:drug therapy; D051379:Mice; D011512:Proteus Infections / Q000188:drug therapy; D011743:Pyrimidines / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000627:therapeutic use; D012481:Salmonella Infections, Animal / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000188:drug therapy; D013290:Streptococcal Infections / Q000188:drug therapy; D013444:Sulfisoxazole / Q000627:therapeutic use; D014295:Trimethoprim / Q000138:chemical synthesis / Q000627:therapeutic use
D000890:Anti-Infective Agents; D011743:Pyrimidines; D013444:Sulfisoxazole; D014295:Trimethoprim