Inhibition of ribonuclease II of Escherichia coli by sodium ions, adenosine-5'-triphosphate, and transfer ribonucleic acid.
Ribonuclease II action on polyuridylate is competitively inhibited by transfer ribonucleic acid and noncompetitively inhibited by sodium ions. At low substrate levels, adenosine-5'-triphosphate is also inhibitory.
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D004926:Escherichia coli / Q000201:enzymology*; D011119:Polynucleotides / Q000378:metabolism; D012343:RNA, Transfer / Q000494:pharmacology*; D012260:Ribonucleases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D012964:Sodium / Q000494:pharmacology*; D014529:Uridine / Q000378:metabolism
D011119:Polynucleotides; D000255:Adenosine Triphosphate; D012343:RNA, Transfer; D012964:Sodium; D012260:Ribonucleases; D014529:Uridine