title: Location and orientation of the phoA locus on the Escherichia coli K-12 linkage map.
abstract: The order of gene loci in the phoA-phoR region of the Escherichia coli K-12 linkage map was demonstrated to be lac phoA proC phoR. The end of the phoA locus corresponding to the amino terminus of alkaline phosphatase was shown to be the end nearer proC. Translation (and transcription) of phoA is therefore in the anticlockwise direction relative to the conventional E. coli linkage map.
mesh_terms: D000469:Alkaline Phosphatase / Q000096:biosynthesis*; D002874:Chromosome Mapping; D003090:Coliphages; D003227:Conjugation, Genetic; D003433:Crosses, Genetic; D003470:Culture Media; D004926:Escherichia coli / Q000201:enzymology* / Q000254:growth & development; D005809:Genes, Regulator; D005815:Genetic Code; D009154:Mutation; D010641:Phenotype; D011995:Recombination, Genetic; D014161:Transduction, Genetic
chemical_list: D003470:Culture Media; D000469:Alkaline Phosphatase