title: Scopafungin, a crystalline antibiotic produced by Streptomyces hygroscopicus var. enhygrus var. nova.
abstract: Scopafungin (U-29,479) is a crystalline, nonpolyenic antimicrobial agent obtained from the culture broth of Streptomyces hygroscopicus var. enhygrus var. nova UC-2397. Scopafungin inhibits, in vitro, a variety of pathogenic fungi, yeasts, and gram-positive bacteria.
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000494:pharmacology; D000935:Antifungal Agents / Q000096:biosynthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001431:Bacteriological Techniques; D002854:Chromatography, Paper; D005285:Fermentation; D005658:Fungi / Q000187:drug effects; D007783:Lactones; D013045:Species Specificity; D013302:Streptomyces / Q000145:classification / Q000254:growth & development / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007783:Lactones; C000770:scopafungin