title: Comment on the use of chloramphenicol to study the initiation of deoxyribonucleic acid synthesis.
abstract: Chloramphenicol cannot be used to distinguish different steps in the initiation of bacterial chromosome replication.
mesh_terms: D002701:Chloramphenicol / Q000494:pharmacology*; D004261:DNA Replication / Q000187:drug effects*; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D005827:Genetics, Microbial; D007930:Leucine / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
chemical_list: D004269:DNA, Bacterial; D014316:Tritium; D002701:Chloramphenicol; D007930:Leucine; D013936:Thymidine