Interconvertible forms of Escherichia coli RNA polymerase.
Escherichia coli RNA polymerase exists in two different forms, one less active than the other under standard assay conditions. Conversion of the active to the inactive form requires ATP-Mg(++). The reverse, inactive to active enzyme conversion, requires Mg(++). Covalently bound adenylic acid residue(s) are contained in the inactive form.
D000255:Adenosine Triphosphate / Q000378:metabolism; D002247:Carbon Isotopes; D002852:Chromatography, Ion Exchange; D004789:Enzyme Activation; D004926:Escherichia coli / Q000201:enzymology*; D005809:Genes, Regulator; D008274:Magnesium / Q000378:metabolism; D010759:Phosphorus Isotopes; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D012329:RNA, Bacterial
D002247:Carbon Isotopes; D010759:Phosphorus Isotopes; D012329:RNA, Bacterial; D000255:Adenosine Triphosphate; D012316:RNA Nucleotidyltransferases; D008274:Magnesium