Effect of the hemolysin of Pseudomonas aeruginosa on phosphatides and on phospholipase c activity.
The hemolysin of Pseudomonas aeruginosa was found to function as a detergent in solubilizing various phosphatides. Incorporation of the hemolysin into reaction mixtures containing phosphatides and phospholipase c significantly increased the rates of enzyme activities. Stimulation of enzyme activity was most likely due to improved dispersion of the substrates.
D002845:Chromatography; D003902:Detergents / Q000494:pharmacology; D006460:Hemolysin Proteins / Q000494:pharmacology*; D010713:Phosphatidylcholines / Q000378:metabolism; D010740:Phospholipases / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000378:metabolism*
D003902:Detergents; D006460:Hemolysin Proteins; D010713:Phosphatidylcholines; D010743:Phospholipids; D010740:Phospholipases