Effect of adrenocorticosteroid on glucose metabolism in BCG-sensitized alveolar macrophages.
The increases in oxidation of glucose-1-(14)C and glucose-6-(14)C in BCG-sensitized alveolar macrophages are inhibited by administration of methylprednisolone sodium succinate. Both resting and phagocytizing cells are affected.
D000818:Animals; D002247:Carbon Isotopes; D005947:Glucose / Q000378:metabolism*; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism*; D008775:Methylprednisolone / Q000494:pharmacology*; D009163:Mycobacterium bovis / Q000276:immunology*; D010084:Oxidation-Reduction; D010587:Phagocytosis / Q000187:drug effects; D011650:Pulmonary Alveoli / Q000187:drug effects / Q000378:metabolism*; D011817:Rabbits / Q000276:immunology
D002247:Carbon Isotopes; D005947:Glucose; D008775:Methylprednisolone