Plasmalogenase activity in normal and demyelinating tissue of the central nervous system.
1. The plasmalogenase activity of brain was found to be associated with the white matter but was absent from myelin fractions. 2. Increased enzyme activity was found in demyelinating spinal cords from vitamin B(12)-deficient monkeys and in white matter from a patient with multiple sclerosis.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001923:Brain Chemistry; D002415:Cats; D002417:Cattle; D003711:Demyelinating Diseases; D004950:Esterases / Q000378:metabolism*; D000882:Haplorhini; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000201:enzymology; D009448:Neurochemistry; D051381:Rats; D013045:Species Specificity; D013116:Spinal Cord / Q000201:enzymology*; D014806:Vitamin B 12 Deficiency / Q000201:enzymology
D004950:Esterases