title: Psilocybin: reaction with a fraction of rat brain.
abstract: Psilocybin, a hallucinogen, formed a blue color with a subfraction of rat-brain mitochondria believed to contain nerve-ending particles. Color formation increased with pH, did not require oxygen, and involved a component that could not be solubilized. The effect was not shown by chemically related neuroactive compounds, such as bufotenine and serotonin, and was antagonized by only tyramine or ethylenediaminetetraacetic acid.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D055598:Chemical Phenomena; D002621:Chemistry; D004492:Edetic Acid; D006213:Hallucinogens; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria; D011562:Psilocybin; D051381:Rats; D012701:Serotonin; D014439:Tyramine
chemical_list: D006213:Hallucinogens; D011562:Psilocybin; D012701:Serotonin; D004492:Edetic Acid; D014439:Tyramine