Agar-gel precipitin-inhibition test for coccidioidomycosis. II. Serological test antigen studies in agar-gel.
In this study of saprophytic and parasitic growth-phase extracts of Coccidioides immitis, an antigen from the spherule culture supernatant fluid detected a specific antibody in heretofore serologically negative suspect coccidioidomycosis human sera when diffused in agar-gel. This antigen-antibody reaction occurred also in some of the serologically positive human coccidioidomycosis sera. This study indicates that this antigen-antibody reaction should be utilized as a possible routine serological test for complete serodiagnosis.
D000906:Antibodies / Q000032:analysis; D000937:Antigen-Antibody Reactions; D000941:Antigens / Q000032:analysis*; D003047:Coccidioidomycosis / Q000175:diagnosis*; D005657:Fungal Vaccines / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D011233:Precipitin Tests
D000906:Antibodies; D000941:Antigens; D005657:Fungal Vaccines