Induction of brain D(--)-beta-hydroxybytrate dehydrogenase activity by fasting.
D(m)-beta-hydroxybutyrate dehydrogenase activity is very low in normal adult rat brain; but during fasting it increases severalfold in parallel with the ketosis. The increase may represent part of a mechanism by which the brain adapts to changing patterns of substrate supply during starvation.
D000090:Acetoacetates / Q000097:blood; D000138:Acidosis; D000818:Animals; D001835:Body Weight; D001921:Brain / Q000166:cytology / Q000201:enzymology*; D004492:Edetic Acid; D004790:Enzyme Induction; D005215:Fasting; D006884:Hydroxybutyrate Dehydrogenase / Q000096:biosynthesis*; D006885:Hydroxybutyrates / Q000097:blood; D008297:Male; D008928:Mitochondria / Q000201:enzymology; D009929:Organ Size; D010713:Phosphatidylcholines / Q000378:metabolism; D051381:Rats
D000090:Acetoacetates; D006885:Hydroxybutyrates; D010713:Phosphatidylcholines; D004492:Edetic Acid; D006884:Hydroxybutyrate Dehydrogenase