Light-chain heterogeneity of cold agglutinins.
Cold agglutinins with specificity to I or to i antigens of humanadult or cord-blood erythrocytes produced during the course of Mycoplasma pneumoniae infection and infectious mononucleosis contain light chains of K and L types. However, cold agglutinin isolated from the serums of patients with chronic cold-agglutinin hemolytic anemia contains only type K light chains. The experimental evidence suggests that some cold agglutinins contain both types of light chains in the same molecule.
D000743:Anemia, Hemolytic / Q000276:immunology*; D000906:Antibodies; D004912:Erythrocytes; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D066298:In Vitro Techniques; D007244:Infectious Mononucleosis / Q000276:immunology*; D009174:Mycoplasma; D011014:Pneumonia / Q000276:immunology*
D000906:Antibodies