Induction of mutants of Staphylococcus aureus 100 with increased ability to produce enterotoxin A.
As a result of serial exposures to a mutagenic agent, N-methyl-N'-nitro-N-nitrosoguanidine, the yield of enterotoxin A produced by the last mutant in the series was increased nearly 20-fold over the amount produced by the parent Staphylococcus aureus 100.
D000818:Animals; D003124:Colorimetry; D003470:Culture Media; D004768:Enterotoxins / Q000009:adverse effects / Q000096:biosynthesis*; D005827:Genetics, Microbial; D006146:Guanidines; D000882:Haplorhini; D007106:Immune Sera; D005779:Immunodiffusion; D009153:Mutagens; D009154:Mutation; D009603:Nitroso Compounds; D013210:Staphylococcus / Q000187:drug effects / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism* / Q000528:radiation effects; D014466:Ultraviolet Rays; D014839:Vomiting / Q000139:chemically induced
D003470:Culture Media; D004768:Enterotoxins; D006146:Guanidines; D007106:Immune Sera; D009153:Mutagens; D009603:Nitroso Compounds