title: Observations on a new disinfectant.
abstract: A disinfectant formula (Resiguard) containing picloxydine digluconate, benzalkonium chloride, and a detergent was examined for antibacterial activity. Studies in vitro with simulated organic contamination were followed by realistic in-use tests employing items of anaesthetic and urological equipment heavily infected with Pseudomonas aeruginosa and contaminated with blood. These showed that a dilution of 1/80 was reliably bactericidal to this resistant organism. It is concluded that Resiguard is a valuable disinfectant which may reliably be employed in the cleaning and disinfection of items of delicate, non-autoclavable, hospital equipment.
mesh_terms: D000758:Anesthesia; D001548:Benzalkonium Compounds / Q000494:pharmacology*; D001769:Blood; D003902:Detergents; D004202:Disinfectants / Q000494:pharmacology*; D004864:Equipment and Supplies; D006146:Guanidines / Q000494:pharmacology*; D007709:Klebsiella / Q000187:drug effects; D010879:Piperazines / Q000494:pharmacology*; D011552:Pseudomonas Infections / Q000517:prevention & control; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013242:Sterilization
chemical_list: D001548:Benzalkonium Compounds; D003902:Detergents; D004202:Disinfectants; D006146:Guanidines; D010879:Piperazines