title: Mutant of Bacillus subtilis demonstrating the requirement of lysis for growth.
abstract: A temperature-sensitive mutant of Bacillus subtilis which has impaired ability to autolyze was isolated. The growth rate of mutant cells at high temperature can be increased by the addition of egg-white lysozyme or a B. subtilis autolysin. Experiments with this mutant show that lysis is essential for cell growth.
mesh_terms: D001412:Bacillus subtilis / Q000166:cytology / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification; D001433:Bacteriolysis; D002473:Cell Wall / Q000187:drug effects; D002712:Chlorides; D003470:Culture Media
chemical_list: D002712:Chlorides; D003470:Culture Media