Urea cycle enzyme adaptation to dietary protein in primates.
Activities of the five hepatic enzymes of the urea cycle increased two- to threefold in monkeys on a 60 percent protein diet compared with levels in monkeys on an isocaloric 6 percent protein diet. Equal adaptation occurred in rats on the same diets. These enzyme activities in adult humans approximate those of monkeys on a similar protein intake.
D000222:Adaptation, Physiological; D000818:Animals; D001119:Arginase / Q000378:metabolism*; D004044:Dietary Proteins; D000882:Haplorhini / Q000378:metabolism*; D008025:Ligases / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008190:Lyases / Q000378:metabolism*; D009954:Ornithine Carbamoyltransferase / Q000378:metabolism*; D010828:Physiology, Comparative; D051381:Rats; D013386:Succinates; D014508:Urea / Q000378:metabolism*
D004044:Dietary Proteins; D013386:Succinates; D014508:Urea; D009954:Ornithine Carbamoyltransferase; D001119:Arginase; D008190:Lyases; D008025:Ligases