New antibacterial agent isolated from the avocado pear.
A group of eight new long-chain aliphatic compounds recently isolated from the avocado and some derivatives thereof were tested for antibacterial activity on 13 different species of bacteria and a yeast. Some of these compounds inhibited the growth of microorganisms. 1,2,4-Trihydroxy-n-hepadeca-16-en was found to be the most active, inhibiting certain gram-positive bacteria at 4 mug/ml.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002175:Candida / Q000187:drug effects / Q000254:growth & development; D055598:Chemical Phenomena; D002621:Chemistry; D005638:Fruit; D005658:Fungi / Q000187:drug effects* / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D012440:Saccharomyces / Q000187:drug effects / Q000254:growth & development; D012485:Salmonella typhi / Q000187:drug effects / Q000254:growth & development; D012762:Shigella dysenteriae / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects / Q000254:growth & development
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents