Levels of dihydrofolate reductase and thymidylate synthetase in strains of Streptococcus faecium resistant to substituted pyrimidines, triazines and MTX.
D002850:Chromatography, Gel; D003470:Culture Media; D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000187:drug effects / Q000201:enzymology*; D005493:Folic Acid Antagonists; D008727:Methotrexate / Q000494:pharmacology*; D008780:Methyltransferases / Q000032:analysis* / Q000037:antagonists & inhibitors; D011485:Protein Binding; D011739:Pyrimethamine / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis*; D013942:Thymine Nucleotides; D014227:Triazines / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology; D014500:Uracil Nucleotides
D003470:Culture Media; D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013942:Thymine Nucleotides; D014227:Triazines; D014500:Uracil Nucleotides; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase; D008780:Methyltransferases; D008727:Methotrexate; D011739:Pyrimethamine