title: Developmental disturbances in children of mothers with dysthyreosis--epidemiological aspect.
abstract: It is the purpose of this work to investigate the possible presence of epidemiological links between dysthyreosis in the mother and developmental disturbances in the child. The clinical material comprised 51 children and 50 mothers. In 60% of cases data on gynaecological disorders could be elicited in the past history of the mothers (spontaneous abortions, premature births, stillbirth etc.). The developmental disturbances in the children showed the pattern of a multisystemic encephalo-endocrinopathy. They were arranged in characteristic clinical syndromes, the age of the child being considered as a criterion (newborn period, infancy, early childhood). The authors suggest that in the mechanism of this encephalo-endocrinopathy damage of the foetal thyroid gland by antithyroid antibodies of the mother could play a role. Further investigations along these lines are being conducted.
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006042:Goiter / Q000175:diagnosis; D006111:Graves Disease / Q000175:diagnosis; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis; D007037:Hypothyroidism / Q000175:diagnosis; D007223:Infant; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000175:diagnosis; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D013959:Thyroid Diseases / Q000175:diagnosis*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones