Australia antigen in a closed adult population monitored for serum glutamic oxalacetic transaminase.
A study of the presence of Australia antigen (Au/SH) was conducted over a period of 21 weeks among volunteer plasma donors living in a prison and being monitored for serum glutamic oxalacetic transaminase (SGOT). A good correlation was observed between the level of SGOT and presence of Au/SH, the latter being present in 33% of donors with SGOT values higher than 101 Karmen units and in 12% of those with SGOT values of 41 to 100 units. Furthermore, none of the 87 donors with all SGOT values below 40 was found positive for Au/SH. It should be noted, however, that single specimens only were tested from 72 of the 87 individuals. Au/SH was detected with equivalent efficiency by both agar gel precipitation and complement fixation procedures. Implications of these findings in the prognostication of hepatitis carrier state are discussed.
D000293:Adolescent; D000328:Adult; D000362:Agar; D001219:Aspartate Aminotransferases / Q000097:blood*; D001782:Blood Donors; D002353:Carrier State / Q000201:enzymology / Q000276:immunology* / Q000382:microbiology; D003168:Complement Fixation Tests; D003937:Diagnosis, Differential; D006509:Hepatitis B / Q000175:diagnosis / Q000276:immunology* / Q000382:microbiology; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D008875:Middle Aged; D011330:Prisons
D000362:Agar; D001219:Aspartate Aminotransferases