Plasmodium malariae: transmission from monkey to man by mosquito bite.
Anopheles freeborni mosquitoes were infected by feeding on New World monkeys, Aotus trivirgatus, infected with a Nigerian strain of Plasmodium malariae. The infection was passed to human volunteers through the bites of these mosquitoes, demonstrating the practicability of using a simian host for infection of mosquitoes with a third species of human malaria parasite and of the use of such mosquitoes to transmit the infection from monkey to man.
D000818:Animals; D000852:Anopheles; D004197:Disease Reservoirs; D000882:Haplorhini; D006801:Humans; D007303:Insect Vectors; D008288:Malaria / Q000209:etiology*; D009549:Nigeria; D010965:Plasmodium malariae / Q000472:pathogenicity*