title: Prototype of a fully automated device for determination of bacterial antibiotic susceptibility in the clinical laboratory.
abstract: A completely automated system for the performance of antibiotic susceptibility tests in the clinical laboratory is described. With a modicum of personnel involvement, data on 40 specimens tested against 13 antibiotics are obtained every hour after an initial 3-hr period. The step by step explanation of the functioning of this prototype system, based on a thoroughly tested manual model, is presented. The system compares well with the standard diffusion test and has a potential for application to other endeavors of the clinical microbiology laboratory with a comparable saving in time and labor.
mesh_terms: D000362:Agar; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001331:Automation; D001419:Bacteria / Q000187:drug effects*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects; D005557:Formaldehyde; D005779:Immunodiffusion; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008722:Methods; D008826:Microbial Sensitivity Tests / Q000295:instrumentation*; D011513:Proteus mirabilis / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media; D005557:Formaldehyde; D000362:Agar