Folate replacement by tetrahydrohomopteroate in triazine-resistant bacteria.
Tetrahydrohomopteroate, which inhibits the growth of Streptococcus faecium (Streptococcus faecalis ATCC 8043), replaces folate as a growth factor in chlorguanide triazine-resistant strains of this organism.
D001431:Bacteriological Techniques; D001565:Benzoates / Q000378:metabolism; D003470:Culture Media; D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D005492:Folic Acid / Q000378:metabolism*; D005947:Glucose; D006133:Growth Substances / Q000378:metabolism; D002727:Proguanil / Q000494:pharmacology*; D011621:Pteridines / Q000378:metabolism*; D014227:Triazines / Q000494:pharmacology
D001565:Benzoates; D003470:Culture Media; D006133:Growth Substances; D011621:Pteridines; D014227:Triazines; D005492:Folic Acid; D005947:Glucose; D002727:Proguanil