title: Is Drosophila dAT on the Y chromosome?
abstract: DNA isolated from Drosophila melanogaster embryos contains measurable amounts of dAT, the copolymer of deoxyadenylate and deoxythymidylate. In wild-type (XX,XY) embryos, dAT constitutes 4% of the total DNA. In embryos containing extra Y chromosomes, or even extra portions of Y chromosomes, dAT constitutes as much as 7% of the total. The enrichment for dAT is dependent upon the number of extra short arms of the Y chromosome (Y(S)) or long arms (Y(L)) of the Y chromosome per individual. This enrichment of dAT dependent on the Y chromosome may be interpreted in several ways. The most straightforward interpretation is that dAT is present in high concentrations on the Y chromosome.
mesh_terms: D000225:Adenine; D000227:Adenine Nucleotides / Q000032:analysis*; D000818:Animals; D002499:Centrifugation, Density Gradient; D002874:Chromosome Mapping; D003470:Culture Media; D004247:DNA / Q000032:analysis* / Q000302:isolation & purification; D004331:Drosophila melanogaster / Q000032:analysis*; D004625:Embryo, Nonmammalian / Q000032:analysis; D005260:Female; D008297:Male; D009691:Nucleic Acid Denaturation; D011108:Polymers / Q000032:analysis; D012730:Sex Chromosomes / Q000032:analysis*; D013941:Thymine; D013942:Thymine Nucleotides / Q000032:analysis*; D014461:Ultracentrifugation
chemical_list: D000227:Adenine Nucleotides; D003470:Culture Media; D011108:Polymers; D013942:Thymine Nucleotides; D004247:DNA; D000225:Adenine; D013941:Thymine