Meningococcal infections. 1. Prevalence of serogroups causing disease in US Army personnel in 1964-70.
Examination of large numbers of strains of meningococci associated with systemic disease in US Army personnel over a 7-year period has shown a changing pattern of sero-group prevalence and an increasing proportion of sulfadiazine-resistant organisms. These findings underline the failure of sulfadiazine prophylaxis and the necessity of applying a specific vaccine to this population. Knowledge of this kind from other populations will be required in order to provide appropriate control measures-vaccine or chemoprophylaxis.
D004352:Drug Resistance, Microbial; D006801:Humans; D008589:Meningococcal Infections / Q000382:microbiology* / Q000517:prevention & control; D008887:Military Medicine; D009345:Neisseria meningitidis / Q000302:isolation & purification; D013411:Sulfadiazine / Q000627:therapeutic use; D014481:United States
D013411:Sulfadiazine