title: The Dyggve-Melchior-Clausen syndrome.
abstract: An  18-year-old mentally retarded girl with short-trunked dwarfism is described as a case of the Dyggve-Melchior-Clausen syndrome. This disorder is characterized by distinctive skeletal radiographic changes, particularly a lacey appearance of the iliac crest. This syndrome appears to be inherited as an autosomal recessive trait. Reports of several cases with similar radiographic changes but without mental retardation suggest heterogeneity within this syndrome.
mesh_terms: D000293:Adolescent; D001842:Bone and Bones / Q000000981:diagnostic imaging; D004392:Dwarfism / Q000000981:diagnostic imaging; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D006820:Hyaluronic Acid / Q000652:urine; D008607:Intellectual Disability; D009083:Mucopolysaccharidoses / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011859:Radiography; D013577:Syndrome
chemical_list: D006820:Hyaluronic Acid