Rhesus isoimmunization after abortion.
Out of 177 Rh(D)-negative patients studied, 96 were successfully followed-up after spontaneous or therapeutic abortion. Rh antibodies were detected by the indirect Coombs test in two patients and by an enzyme technique only in a further seven, an overall incidence of 9.4%.The prophylactic use of anti-D immunoglobulin is now recommended for Rh-negative non-immunized patients undergoing abortion, but the dose could be less than 75 mug. The Kleihauer test was of no value in predicting the risk of isoimmunization.
D000022:Abortion, Spontaneous / Q000276:immunology*; D000033:Abortion, Threatened; D000293:Adolescent; D000917:Antibody Formation; D003298:Coombs Test; D004899:Erythroblastosis, Fetal / Q000517:prevention & control*; D005260:Female; D005331:Fetomaternal Transfusion; D005500:Follow-Up Studies; D006801:Humans; D007114:Immunization; D007136:Immunoglobulins / Q000627:therapeutic use; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System; D013997:Time Factors
D007136:Immunoglobulins; D012204:Rh-Hr Blood-Group System