title: A macroglobulin with inhibitory activity against coagulation factor VIII.
mesh_terms: D000327:Adsorption; D001778:Blood Coagulation Disorders / Q000097:blood / Q000209:etiology*; D001780:Blood Coagulation Tests; D001803:Blood Transfusion; D002699:Chlorambucil / Q000627:therapeutic use; D003018:Clot Retraction; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000378:metabolism; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D008259:Macroglobulins / Q000378:metabolism*; D008623:Mercaptoethanol / Q000494:pharmacology / Q000627:therapeutic use; D008875:Middle Aged; D009588:Nitrogen Mustard Compounds / Q000627:therapeutic use; D010396:Penicillamine / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D010956:Plasmapheresis; D010973:Platelet Adhesiveness; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology* / Q000628:therapy
chemical_list: D007075:Immunoglobulin M; D008259:Macroglobulins; D009588:Nitrogen Mustard Compounds; D010406:Penicillins; D002699:Chlorambucil; D008623:Mercaptoethanol; D005169:Factor VIII; D010396:Penicillamine