Reactivity of two gonococcal antigens in an automated microhemagglutination procedure.
In studies of several hundred sera, a passive-hemagglutination technique with soluble antigen of sonically treated gonococci as the sensitizing material for tanned erythrocytes and Neisseria sicca sonically treated material as an absorbent detected gonococcal antibodies in 77% of males and 88% of females infected with uncomplicated gonorrhea. However, 6% of the sera from individuals in celibate religious orders and 18% of the sera from a group of females having cervical cultures negative for gonococci were also reactive with this procedure. Erythrocytes sensitized with an alkaline extract of gonococci reacted with 23% of the sera from infected males, 49% of the sera from infected females, and 2% of the sera from celibate females.
D000042:Absorption; D000818:Animals; D000906:Antibodies / Q000032:analysis; D000941:Antigens; D003429:Cross Reactions; D003937:Diagnosis, Differential; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008722:Methods; D009343:Neisseria / Q000276:immunology; D009344:Neisseria gonorrhoeae / Q000276:immunology*; D012756:Sheep; D014732:Vibration
D000906:Antibodies; D000941:Antigens