title: Isolation and preliminary characterization of developmental mutants from Microsporum gypseum.
abstract: Developmental mutants affected in either sporulation or spore germination have been isolated from Microsporum gypseum with the aid of nitrosoguanidine or as spontaneously occurring mutants. The time course levels of several proteins temporally associated with conidial development have been assayed in the wild-type and mutant strains. The spore germination characteristics of two of the mutants are described. The relationship of alkaline protease accumulation to tyrosinase accumulation and spore germination is discussed.
mesh_terms: D000217:Acyltransferases / Q000378:metabolism; D004156:Catechol Oxidase / Q000378:metabolism; D003470:Culture Media; D005827:Genetics, Microbial; D006146:Guanidines; D008864:Microsporum / Q000201:enzymology / Q000254:growth & development / Q000302:isolation & purification*; D009153:Mutagens; D009154:Mutation; D009603:Nitroso Compounds; D010447:Peptide Hydrolases / Q000378:metabolism; D013053:Spectrophotometry; D013170:Spores / Q000201:enzymology / Q000254:growth & development
chemical_list: D003470:Culture Media; D006146:Guanidines; D009153:Mutagens; D009603:Nitroso Compounds; D004156:Catechol Oxidase; D000217:Acyltransferases; D010447:Peptide Hydrolases