Spectra of susceptibility of Neisseria meningitidis to antimicrobial agents in vitro.
The minimal inhibitory concentrations of 49 antimicrobial agents for 37 to 40 meningococcal strains freshly isolated from the nasopharynx of healthy carriers were determined. Coumermycin A(1) and rifampin were the most effective agents tested. The geometric mean values of the minimal inhibitory concentrations for coumermycin A(1) and rifampin were 0.0001 and 0.02 mug/ml, respectively.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D002353:Carrier State; D004202:Disinfectants / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009305:Nasopharynx / Q000382:microbiology; D009345:Neisseria meningitidis / Q000187:drug effects*; D011758:Pyrroles / Q000494:pharmacology; D012293:Rifampin / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D011758:Pyrroles; D013449:Sulfonamides; D012293:Rifampin