Antimicrobial activity of sodium n-alkylsalicylates.
The activities are reported of sodium salts of several n-alkylsalicylic acids against Staphylococcus aureus, Pseudomonas aeruginosa, Mycobacterium phlei, and Candida albicans. The acids had alkyl substituents of 1 to 18 carbon atoms in the 3, 4, or 5 positions relative to the carboxyl group of salicylic acid. Generally, the antimicrobial properties were typical of anionic surface-active agents although the salicylates are more potent than most of these, particularly against S. aureus.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D003720:Densitometry; D004352:Drug Resistance, Microbial; D008854:Microscopy, Electron; D009161:Mycobacterium / Q000187:drug effects* / Q000254:growth & development; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000254:growth & development; D012459:Salicylates / Q000494:pharmacology*; D012964:Sodium; D013053:Spectrophotometry; D013210:Staphylococcus / Q000187:drug effects* / Q000254:growth & development
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D012459:Salicylates; D012964:Sodium