The effect of fat on calcium absorption from a mixed meal in normal subjects, patients with malabsorptive disease, and patients with a partial gastrectomy.
The absorption of (47)Ca Cl(2) taken with a milk and porridge meal was measured in normal subjects, patients with a partial gastrectomy, and patients with malabsorption. The addition of palm oil to the meal depressed calcium absorption, whereas the addition of medium-chain triglyceride had no effect. The contrasting effect of the two fats on calcium absorption was most marked in patients with a partial gastrectomy and least marked in patients with malabsorption. In patients with malabsorption, impairment of calcium absorption was most marked in the patients with a significant increase in faecal fat excretion. Absorption of calcium was greater in patients with a partial gastrectomy than in normal subjects.
D002118:Calcium / Q000097:blood; D002127:Calcium Isotopes; D002136:Calcium, Dietary / Q000378:metabolism*; D003864:Depression, Chemical; D004041:Dietary Fats / Q000032:analysis; D005243:Feces / Q000032:analysis; D005743:Gastrectomy; D006801:Humans; D007408:Intestinal Absorption; D008286:Malabsorption Syndromes / Q000378:metabolism*; D014280:Triglycerides; D014915:Whole-Body Counting
D002127:Calcium Isotopes; D002136:Calcium, Dietary; D004041:Dietary Fats; D014280:Triglycerides; D002118:Calcium