title: Detection of a beta-lactamase markedly active against carbenicillin in a strain of Pseudomonas aeruginosa.
abstract: Examination of the substrate profile of a number of beta-lactamases synthesized by strains of Pseudomonas aeruginosa has shown the presence of at least two distinct types of enzyme, one of which is more active against carbenicillin than against benzyl penicillin.
mesh_terms: D000581:Amidohydrolases / Q000378:metabolism; D000667:Ampicillin / Q000378:metabolism; D002509:Cephaloridine / Q000378:metabolism; D004586:Electrophoresis; D005782:Gels; D006571:Heterocyclic Compounds; D010400:Penicillin G / Q000378:metabolism; D010403:Penicillin Resistance; D010405:Penicillinase; D010406:Penicillins / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology*; D013053:Spectrophotometry; D013213:Starch
chemical_list: D005782:Gels; D006571:Heterocyclic Compounds; D010406:Penicillins; D000667:Ampicillin; D013213:Starch; D000581:Amidohydrolases; D010405:Penicillinase; D002509:Cephaloridine; D010400:Penicillin G