Antimalarial activity of 2,4-diamino-6-[(3,4-dichlorobenzyl) nitros-amino] quinazoline (CI-679 base) and CI-679 acetate. Laboratory studies in mice and rhesus monkeys.
D000085:Acetates / Q000627:therapeutic use; D062365:Aminobenzoates / Q000494:pharmacology; D000818:Animals; D000962:Antimalarials / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D003622:Dapsone / Q000494:pharmacology; D004357:Drug Synergism; D005260:Female; D005492:Folic Acid / Q000494:pharmacology; D000882:Haplorhini; D006846:Hydrocarbons, Halogenated / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D009602:Nitrosamines / Q000627:therapeutic use*; D010961:Plasmodium / Q000145:classification / Q000187:drug effects; D011799:Quinazolines / Q000627:therapeutic use*
D000085:Acetates; D062365:Aminobenzoates; D000962:Antimalarials; D006846:Hydrocarbons, Halogenated; D009602:Nitrosamines; D011799:Quinazolines; D003622:Dapsone; D005492:Folic Acid