Chemoprophylactic agent in schistosomiasis: 14,15-epoxygeranylgeraniol.
The occurrence of all-trans (-)-14,15-epoxygeranyl-geraniol in Pterodon pubescens Benth. is established, and its prophylactic activity against infection by Schitsosma mansoni demonstrated. Two other diterpenes present in the oil are inactive.
D000818:Animals; D004224:Diterpenes / Q000627:therapeutic use*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D010938:Plant Oils / Q000032:analysis / Q000627:therapeutic use*; D012555:Schistosomiasis mansoni / Q000517:prevention & control*
D004224:Diterpenes; D010938:Plant Oils