Radiometric method for detection of bacteremia.
A study was performed with simulated blood cultures to evaluate the production of (14)CO(2) as an index of bacterial growth. With a range of inoculum sizes from 4 to 4,250 colony-forming units, it was not possible to detect (14)CO(2) within 6 hr after inoculation in 59 separate experiments. In a limited trial with patients' blood cultures, the radiometric method failed to provide any earlier evidence of bacteremia than did routine broth cultures.
D001431:Bacteriological Techniques; D001439:Bacteroides / Q000302:isolation & purification / Q000378:metabolism; D002175:Candida / Q000302:isolation & purification / Q000378:metabolism; D002245:Carbon Dioxide / Q000096:biosynthesis; D002247:Carbon Isotopes; D003937:Diagnosis, Differential; D004926:Escherichia coli / Q000302:isolation & purification* / Q000378:metabolism; D005069:Evaluation Studies as Topic; D005947:Glucose / Q000378:metabolism; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification* / Q000378:metabolism; D018805:Sepsis / Q000175:diagnosis* / Q000382:microbiology; D013210:Staphylococcus / Q000302:isolation & purification* / Q000378:metabolism; D013291:Streptococcus / Q000302:isolation & purification* / Q000378:metabolism
D002247:Carbon Isotopes; D002245:Carbon Dioxide; D005947:Glucose