Hamster-tropic sarcomagenic and nonsarcomagenic viruses derived from hamster tumors induced by the Gross pseudotype of Moloney sarcoma virus.
Hamster sarcomas induced by the Gross pseudotype of Moloney sarcoma virus yielded a virus sarcomagenic for hamsters but not mice. This virus was able to produce foci on hamster embryo cells, but not on mouse embryo cells. A hamster-tropic nonfocus-forming helper virus was also found in the viral stocks. These hamster-tropic viruses are not immunologically related to the murine viruses in the original inoculum but appear to represent indigenous C-type RNA viruses of the hamster.
D000406:AKR murine leukemia virus / Q000276:immunology / Q000472:pathogenicity; D000818:Animals; D002471:Cell Transformation, Neoplastic; D003168:Complement Fixation Tests; D006224:Cricetinae; D046508:Culture Techniques; D004622:Embryo, Mammalian / Q000166:cytology; D005347:Fibroblasts / Q000382:microbiology; D006378:Helper Viruses / Q000472:pathogenicity; D005779:Immunodiffusion; D007680:Kidney Neoplasms / Q000382:microbiology; D008113:Liver Neoplasms / Q000382:microbiology; D008223:Lymphoma / Q000382:microbiology; D051379:Mice; D008854:Microscopy, Electron; D008979:Moloney murine leukemia virus / Q000276:immunology / Q000472:pathogenicity; D009500:Neutralization Tests; D012513:Sarcoma, Experimental; D013160:Splenic Neoplasms / Q000382:microbiology; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D014316:Tritium; D014529:Uridine