[Possibility of the use of biochemical mutants of microorganisms for preliminary characterization of the mechanism of action of new antibiotics].
D000190:Actinomyces / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D001412:Bacillus subtilis / Q000187:drug effects* / Q000254:growth & development; D003864:Depression, Chemical; D005827:Genetics, Microbial; D051379:Mice; D008826:Microbial Sensitivity Tests; D009154:Mutation; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D009696:Nucleic Acids / Q000037:antagonists & inhibitors; D011506:Proteins / Q000037:antagonists & inhibitors; D013210:Staphylococcus / Q000187:drug effects* / Q000254:growth & development
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D009696:Nucleic Acids; D011506:Proteins
O vozmozhnosti ispol'zovaniia biokhimicheskikh mutantov mikroorganizmov dlia predvaritel'noĭ kharakteristiki mekhanizma deĭstviia novykh antibiotikov.