[Demonstration of the inhibitory effect of clofibrate (ethyl parachlorophenoxyisobutyrate) on the biosynthesis of 18-hydroxycorticosterone and aldosterone by incubation of a human adrenal gland and sheep adrenal glands in vitro].
D000305:Adrenal Cortex Hormones / Q000096:biosynthesis*; D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism*; D000450:Aldosterone / Q000096:biosynthesis*; D000818:Animals; D002247:Carbon Isotopes; D002994:Clofibrate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006889:Hydroxycorticosteroids / Q000096:biosynthesis; D066298:In Vitro Techniques; D012756:Sheep; D014316:Tritium
D000305:Adrenal Cortex Hormones; D002247:Carbon Isotopes; D006889:Hydroxycorticosteroids; D014316:Tritium; D000450:Aldosterone; D002994:Clofibrate
Mise en évidence de l'effet inhibiteur du clofibrate (parachlorophénoxyisobutyrate d'éthyle) sur la biosynthèse de la 18-hydroxycorticostérone et de l'aldostérone par incubation d'une surrénale humain et des surrénales de moutons in vitro.