Nephrotic syndrome in monkey infected with human quartan malaria.
A splenectomized aotus monkey infected with human quartan malaria (Plasmodium malariae) developed oedema and proteinuria. Histological examination revealed a generalized diffuse glomerulonephritis and immunofluorescent staining showed granular deposits of IgM in the glomeruli. The pathological picture resembled that shown by human patients with the quartan malaria nephrotic syndrome.
D000818:Animals; D004487:Edema / Q000209:etiology; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000209:etiology; D000882:Haplorhini; D007075:Immunoglobulin M / Q000032:analysis; D007678:Kidney Glomerulus / Q000032:analysis / Q000473:pathology; D008288:Malaria / Q000150:complications*; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000473:pathology; D011507:Proteinuria / Q000209:etiology; D013156:Splenectomy
D007075:Immunoglobulin M