Induction of histidine-degrading enzymes in Pseudomonas aeruginosa.
Urocanate but not histidine was able to induce formation of histidine-degrading enzymes in a histidine ammonia-lyase-deficient mutant of Pseudomonas aeruginosa. The results, in conjunction with others reported previously, indicate that urocanate, the first intermediate, is the physiological inducer of the pathway.
D000179:Acrylates; D002247:Carbon Isotopes; D002951:Citrates / Q000378:metabolism; D004790:Enzyme Induction; D005827:Genetics, Microbial; D006639:Histidine / Q000378:metabolism*; D007093:Imidazoles / Q000494:pharmacology*; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology*
D000179:Acrylates; D002247:Carbon Isotopes; D002951:Citrates; D007093:Imidazoles; D006639:Histidine