Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells.
Monkey-kidney cells bearing new surface antigens induced by infection with mumps virus were lysed selectively by diphtheria toxin conjugated to antibody against mumps antigens.
D000818:Animals; D000937:Antigen-Antibody Reactions; D046508:Culture Techniques; D003485:Cyanates; D003588:Cytopathogenic Effect, Viral; D004167:Diphtheria Toxin / Q000633:toxicity*; D000882:Haplorhini; D007668:Kidney / Q000276:immunology* / Q000382:microbiology; D007930:Leucine / Q000378:metabolism; D009109:Mumps virus / Q000276:immunology* / Q000472:pathogenicity
D003485:Cyanates; D004167:Diphtheria Toxin; D007930:Leucine