Actinomycin resistance and actinomycin excretion in a mutant of Escherichia coli.
A mutant of Escherichia coli resembles its parent in taking up actinomycin after treatment with ethylenediaminetetraacetic acid but differs in that it survives this uptake and excretes actinomycin at an increased rate.
D002247:Carbon Isotopes; D002854:Chromatography, Paper; D003609:Dactinomycin / Q000378:metabolism* / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004492:Edetic Acid / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D005827:Genetics, Microbial; D009154:Mutation; D012329:RNA, Bacterial / Q000096:biosynthesis; D014498:Uracil / Q000378:metabolism
D002247:Carbon Isotopes; D012329:RNA, Bacterial; D003609:Dactinomycin; D014498:Uracil; D004492:Edetic Acid