Steroid nitrogen compounds. 3. A general method for introduction of O, N, S and other functionality into position-5 of cholestanes. Conjugate addition of nucleophiles to 6-nitrosocholesteryl acetate generated in situ from the 5 -chloro-6-oxime.
D000085:Acetates / Q000138:chemical synthesis; D000641:Ammonia; D001386:Azides; D002776:Cholestanes / Q000138:chemical synthesis*; D002784:Cholesterol / Q000138:chemical synthesis; D003486:Cyanides; D000431:Ethanol; D007259:Infrared Rays; D009682:Magnetic Resonance Spectroscopy; D008744:Methylamines; D009573:Nitrites; D009603:Nitroso Compounds / Q000138:chemical synthesis*; D009904:Optical Rotation; D010091:Oximes / Q000138:chemical synthesis*; D013057:Spectrum Analysis; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds; D013861:Thiocyanates
D000085:Acetates; D001386:Azides; D002776:Cholestanes; D003486:Cyanides; D008744:Methylamines; D009573:Nitrites; D009603:Nitroso Compounds; D010091:Oximes; D013438:Sulfhydryl Compounds; D013861:Thiocyanates; D000431:Ethanol; D000641:Ammonia; D002784:Cholesterol