Effect of colchicine and vinblastine on the topographical separation of membrane functions.
The topographical separation of membrane functions into phagocytic and transport areas, inferred from physiological studies, is not demonstrable in cells treated with colchicine and vinblastine, alkaloids which bind to microtubular proteins.
D000225:Adenine / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D003078:Colchicine / Q000494:pharmacology*; D003864:Depression, Chemical; D066298:In Vitro Techniques; D008239:Lysine / Q000378:metabolism; D008566:Membranes / Q000378:metabolism*; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism*; D009504:Neutrophils / Q000378:metabolism*; D010587:Phagocytosis; D011485:Protein Binding; D011817:Rabbits; D014747:Vinblastine / Q000494:pharmacology*
D014747:Vinblastine; D000225:Adenine; D008239:Lysine; D003078:Colchicine