A toxicologic comparison of the potency and activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in mice and rats.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003510:Cyclohexanes / Q000633:toxicity; D005260:Female; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009603:Nitroso Compounds / Q000633:toxicity*; D009607:Nitrosourea Compounds / Q000633:toxicity; D012737:Sex Factors; D013045:Species Specificity; D013997:Time Factors; D014508:Urea / Q000633:toxicity*
D003510:Cyclohexanes; D009603:Nitroso Compounds; D009607:Nitrosourea Compounds; D014508:Urea