Extragastric gastrin.
Gastrin release in the basal state and following a standard protein meal has been estimated in patients after partial gastrectomy, partial gastrectomy with truncal vagotomy, and total gastrectomy. Following partial gastrectomy, gastrin rose from 8 +/- 0.8 to 20 +/- 3.8 pg/ml with a protein meal. The rise in the partial gastrectomy with truncal vagotomy group was 27 +/- 0.8 to 92 +/- 1.5 pg/ml and after total gastrectomy was 13 +/- 1.5 to 58 +/- 4.6 pg/ml. These results provide evidence for the release of gastrin from extragastric sites.
D000328:Adult; D004044:Dietary Proteins; D005260:Female; D005743:Gastrectomy; D005755:Gastrins / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014628:Vagotomy
D004044:Dietary Proteins; D005755:Gastrins