A proposed mode of action of antitumor platinum compounds based upon studies with cis-dichloro-((G- 3 H)dipyridine)platinum(II).
D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism*; D002247:Carbon Isotopes; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002713:Chlorine / Q000378:metabolism; D004247:DNA; D004912:Erythrocytes / Q000378:metabolism; D007700:Kinetics; D008466:Mechlorethamine; D051379:Mice; D009942:Organometallic Compounds / Q000378:metabolism*; D010984:Platinum / Q000378:metabolism / Q000494:pharmacology*; D011119:Polynucleotides; D011725:Pyridines / Q000378:metabolism; D012313:RNA; D012343:RNA, Transfer; D013696:Temperature; D014316:Tritium
D000970:Antineoplastic Agents; D002247:Carbon Isotopes; D009942:Organometallic Compounds; D011119:Polynucleotides; D011725:Pyridines; D014316:Tritium; D010984:Platinum; D002713:Chlorine; D008466:Mechlorethamine; D012313:RNA; D004247:DNA; D012343:RNA, Transfer