Application of clearance concepts to some literature data on drug metabolism in the isolated perfused liver preparation and in vivo.
D000700:Analgesics / Q000378:metabolism*; D000818:Animals; D000928:Antidepressive Agents / Q000378:metabolism*; D000983:Antipyrine / Q000097:blood / Q000378:metabolism; D003891:Desipramine / Q000097:blood / Q000378:metabolism; D006207:Half-Life; D066298:In Vitro Techniques; D007659:Ketones / Q000097:blood / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008954:Models, Biological; D009661:Nortriptyline / Q000097:blood / Q000378:metabolism; D010477:Perfusion; D010653:Phenylbutazone / Q000097:blood / Q000378:metabolism; D051381:Rats; D014203:Tremorine / Q000097:blood / Q000378:metabolism
D000700:Analgesics; D000928:Antidepressive Agents; D007659:Ketones; D009661:Nortriptyline; D010653:Phenylbutazone; D000983:Antipyrine; D003891:Desipramine; D014203:Tremorine