Studies on the biosynthetic conversion of cholesterol into pregnenolone. Side chain cleavage of a t-butyl analog of 20 -hydroxycholesterol, (20R(-t-butyl-5-pregnene-3 ,20-diol, a compound completely substituted at C-22.
D000311:Adrenal Glands / Q000166:cytology / Q000378:metabolism*; D000438:Alcohols / Q000138:chemical synthesis / Q000378:metabolism*; D000478:Alkylation; D000818:Animals; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D002845:Chromatography; D002855:Chromatography, Thin Layer; D005260:Female; D008094:Lithium; D008928:Mitochondria / Q000378:metabolism; D008956:Models, Chemical; D009942:Organometallic Compounds; D011276:Pregnanediol / Q000652:urine; D011278:Pregnanes / Q000138:chemical synthesis / Q000378:metabolism*; D011284:Pregnenolone / Q000096:biosynthesis*; D011817:Rabbits; D014316:Tritium
D000438:Alcohols; D009942:Organometallic Compounds; D011278:Pregnanes; D014316:Tritium; D011284:Pregnenolone; D008094:Lithium; D011276:Pregnanediol