An automated screening technique for the detection of sickle-cell haemoglobin.
An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment.
D000755:Anemia, Sickle Cell / Q000097:blood / Q000175:diagnosis*; D001322:Autoanalysis; D002021:Buffers; D003937:Diagnosis, Differential; D006445:Hemoglobin C Disease / Q000097:blood; D006452:Hemoglobinometry / Q000295:instrumentation; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans
D002021:Buffers; D006455:Hemoglobins, Abnormal