In vivo effects of methotrexate. Inhibition of DNA synthesis and cell death in sensitive and resistant L1210 ascites populations.
D000818:Animals; D002452:Cell Count; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured / Q000187:drug effects; D004261:DNA Replication / Q000187:drug effects; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003857:Deoxyuridine / Q000378:metabolism; D003864:Depression, Chemical; D004351:Drug Resistance; D005260:Female; D007274:Injections, Intraperitoneal; D007456:Iodine Isotopes; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism*; D008727:Methotrexate / Q000008:administration & dosage / Q000494:pharmacology*; D051379:Mice; D008815:Mice, Inbred Strains; D013997:Time Factors
D004273:DNA, Neoplasm; D007456:Iodine Isotopes; D003857:Deoxyuridine; D008727:Methotrexate