Evidence for the His-57 sidechain acting as a general base in the "ageing" and reactivation reactions of carbonate-inhibited  -chymotrypsin.
D001665:Binding Sites; D002254:Carbonates; D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D004789:Enzyme Activation; D004952:Esters; D006639:Histidine; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles; D007700:Kinetics; D009596:Nitrophenols; D010756:Phosphoric Acids
D002254:Carbonates; D004952:Esters; D007093:Imidazoles; D009596:Nitrophenols; D010756:Phosphoric Acids; D006639:Histidine; D002918:Chymotrypsin