The membrane concentrations of neutral and positive anesthetics (alcohols, chlorpromazine, morphine) fit the Meyer-Overton rule of anesthesia; negative narcotics do not.
D000438:Alcohols / Q000378:metabolism; D000777:Anesthetics / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D001463:Barbiturates / Q000378:metabolism; D002247:Carbon Isotopes; D002462:Cell Membrane / Q000378:metabolism; D002746:Chlorpromazine / Q000378:metabolism; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D006168:Guinea Pigs; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008566:Membranes / Q000378:metabolism*; D009020:Morphine / Q000378:metabolism; D009411:Nerve Endings / Q000378:metabolism*; D010636:Phenols / Q000378:metabolism; D011343:Procaine / Q000378:metabolism; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*; D013460:Sulfur Isotopes; D013572:Synaptic Vesicles / Q000378:metabolism*; D013574:Synaptosomes / Q000166:cytology / Q000378:metabolism; D014631:Valerates / Q000378:metabolism
D000438:Alcohols; D000777:Anesthetics; D001463:Barbiturates; D002247:Carbon Isotopes; D005230:Fatty Acids, Nonesterified; D010636:Phenols; D013460:Sulfur Isotopes; D014631:Valerates; D011343:Procaine; D009020:Morphine; D002746:Chlorpromazine