Pernicious anaemia and rheumatoid arthritis.
In a study of 99 patients with pernicious anaemia the incidence of clinical rheumatoid arthritis was normal but rheumatoid factor was present significantly more often than in controls. This was not related to the presence of circulating antibody to intrinsic factor.Intrinsic factor antibody was not detected in any of 151 latex-fixation-positive rheumatoid sera.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000752:Anemia, Pernicious / Q000150:complications* / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006801:Humans; D007437:Intrinsic Factor / Q000032:analysis; D007841:Latex Fixation Tests; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis
D001323:Autoantibodies; D007437:Intrinsic Factor; D012217:Rheumatoid Factor