title: Primary negative inotropic effect of tris(hydroxymethyl)aminomethane.
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D002245:Carbon Dioxide / Q000378:metabolism; D002415:Cats; D005110:Extracellular Space; D006863:Hydrogen-Ion Concentration; D009119:Muscle Contraction / Q000187:drug effects*; D009994:Osmolar Concentration; D010210:Papillary Muscles / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014325:Tromethamine / Q000494:pharmacology*
chemical_list: D001639:Bicarbonates; D014325:Tromethamine; D002245:Carbon Dioxide; D012964:Sodium