Relationship between inhibition of prostaglandin synthesis and drug efficacy: support for the current theory on mode of action of aspirin-like drugs.
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001095:Arachidonic Acids / Q000378:metabolism; D001241:Aspirin / Q000494:pharmacology; D002247:Carbon Isotopes; D002417:Cattle; D002855:Chromatography, Thin Layer; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism; D009281:Naphthalenes / Q000494:pharmacology; D011422:Propionates / Q000494:pharmacology; D011453:Prostaglandins / Q000096:biosynthesis*; D012669:Seminal Vesicles / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D013237:Stereoisomerism
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D001095:Arachidonic Acids; D002247:Carbon Isotopes; D009281:Naphthalenes; D011422:Propionates; D011453:Prostaglandins; D001241:Aspirin; D007213:Indomethacin