Antitumor activity of some derivatives of daunorubicin at the amino and methyl ketone functions.
D000215:Acylation; D000588:Amines / Q000008:administration & dosage / Q000138:chemical synthesis / Q000627:therapeutic use; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000627:therapeutic use; D002855:Chromatography, Thin Layer; D003630:Daunorubicin / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000627:therapeutic use; D007274:Injections, Intraperitoneal; D007659:Ketones / Q000008:administration & dosage / Q000138:chemical synthesis / Q000627:therapeutic use; D007939:Leukemia L1210 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D009904:Optical Rotation; D013329:Structure-Activity Relationship
D000588:Amines; D000903:Antibiotics, Antineoplastic; D007659:Ketones; D003630:Daunorubicin