Acylation of chymotrypsin by active esters of nonspecific substrates. Evidence for a transient acylimidazole intermediate.
D000215:Acylation; D001565:Benzoates; D002384:Catalysis; D055598:Chemical Phenomena; D002621:Chemistry; D002918:Chymotrypsin; D003903:Deuterium; D004140:Dinitrophenols; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles; D007700:Kinetics; D008433:Mathematics; D008956:Models, Chemical; D009596:Nitrophenols; D011485:Protein Binding; D012694:Serine; D013329:Structure-Activity Relationship
D001565:Benzoates; D004140:Dinitrophenols; D007093:Imidazoles; D009596:Nitrophenols; D012694:Serine; D003903:Deuterium; D002918:Chymotrypsin