Decreased RNA polymerase activity in mammalian zinc deficiency.
The activity of DNA-dependent RNA polymerase has been measured in liver nuclei from suckling rats nursed by zinc-deficient dams, or by controls that were either pair-fed or given free access to the diet. In the zinc-deficient pups, the activity of the enzyme did not increase; it fell after the tenth day of life.
D000375:Aging; D000818:Animals; D001835:Body Weight; D002467:Cell Nucleus / Q000201:enzymology; D004247:DNA / Q000378:metabolism; D003677:Deficiency Diseases / Q000201:enzymology*; D004032:Diet; D005260:Female; D005865:Gestational Age; D008099:Liver / Q000201:enzymology; D011247:Pregnancy; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D051381:Rats; D013217:Starvation; D015032:Zinc
D004247:DNA; D012316:RNA Nucleotidyltransferases; D015032:Zinc