title: A correlative histocytological study of carcinoma and epithelial atypia of the palate among Indian reverse smokers.
abstract: A correlative histocytological study was made of 6 patients with palatal carcinomata and 342 patients with palatal lesions (primarily leukoplakias) associated with reverse smoking from the Srikakulam district of Andhra Pradesh. Among 6 histologically diagnosed carcinomata only 2 showed cytological findings typical of carcinoma. Of the 46 atypias diagnosed histologically among the other palatal lesions, only 6 (13%) were diagnosed cytologically. Our findings show that cytological examination of precancerous and cancerous lesions located on the hard palate, which is a highly keratinized area of the oral cavity, may not be reliable enough for revealing premalignant or malignant changes.
mesh_terms: D003581:Cytodiagnosis; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007194:India; D007633:Keratins; D007972:Leukoplakia, Oral / Q000175:diagnosis / Q000473:pathology; D010157:Palatal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D010159:Palate / Q000473:pathology*; D011230:Precancerous Conditions / Q000175:diagnosis / Q000473:pathology*; D012907:Smoking / Q000473:pathology*
chemical_list: D007633:Keratins