Ovulation in hamster: induction by subunit of ovine interstitial cell stimulating hormone.
As little as 5 micrograms of interstitial cell stimulating hormone (ICSH) or 20 micrograms of ICSH-beta is effective for the induction of ovulation in 100 percent of hamsters treated at 0500 hours on day 4 after lordosis, whereas as much as 800 micrograms of ICSH-alpha is ineffective. Both ICSH and ICSH-beta are also effective for induction of ovulation in hypophysectomized animals. Thus, the ovulation-inducing activity of the ICSH molecule resides in its beta subunit.
D000818:Animals; D006224:Cricetinae; D004971:Estrus; D005260:Female; D007016:Hypophysectomy; D007274:Injections, Intraperitoneal; D007986:Luteinizing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D010060:Ovulation / Q000187:drug effects*; D011247:Pregnancy; D013268:Stimulation, Chemical; D013997:Time Factors
D007986:Luteinizing Hormone