title: In vitro and in vivo inhibition of hepatic cholesterol synthesis by 3-hydroxy-3-methylglutaric acid.
mesh_terms: D000085:Acetates / Q000378:metabolism; D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors; D000818:Animals; D002245:Carbon Dioxide / Q000096:biosynthesis; D002247:Carbon Isotopes; D002784:Cholesterol / Q000096:biosynthesis* / Q000097:blood / Q000494:pharmacology; D002952:Citric Acid Cycle / Q000187:drug effects; D003065:Coenzyme A / Q000378:metabolism; D003864:Depression, Chemical; D004041:Dietary Fats; D005977:Glutarates / Q000378:metabolism / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008798:Mevalonic Acid / Q000378:metabolism; D051381:Rats; D013347:Subcellular Fractions / Q000187:drug effects / Q000378:metabolism
chemical_list: D000085:Acetates; D002247:Carbon Isotopes; D004041:Dietary Fats; D005977:Glutarates; D002245:Carbon Dioxide; D002784:Cholesterol; D000429:Alcohol Oxidoreductases; D008798:Mevalonic Acid; D003065:Coenzyme A