Disordered blood coagulation in burned children receiving high molecular weight dextran.
Coagulation studies were performed on nine children with burns. Four of these children received treatment which included intravenous dextran; all four showed abnormalities of coagulation and two of them developed a bleeding state. No abnormalities of haemostasis were detected in the remaining five children who had comparable degrees of burns but whose treatment did not include intravenous dextran.
D001777:Blood Coagulation / Q000187:drug effects; D001778:Blood Coagulation Disorders / Q000139:chemically induced*; D001780:Blood Coagulation Tests; D001792:Blood Platelets / Q000187:drug effects; D002056:Burns / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003911:Dextrans / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced; D006487:Hemostasis; D006801:Humans; D007223:Infant; D007263:Infusions, Parenteral; D008297:Male; D011517:Prothrombin Time; D013997:Time Factors
D003911:Dextrans