title: Some parallelisms n the behavior of pancreatic ribonuclease and chicken lysozyme toward homopolyribonucleotides.
abstract: Pancreatic ribonuclease and chicken lysozyme possess gross similarities that are responsible for a common ability to form enormous light-scattering centers in cooperation with homopolyribonucleotides. The light-scattering power of the mixtures is highest when [homopolymer]/[protein] assumes some critical value that is unique for each homopolymer-protein pair. In some respects the scatterers resemble very large antigen-antibody networks. A criterion is established to ascertain the relative abilities of the homopolymers to form the centers with the two proteins. Both see polyinosinic acid (poly-I) as most and polyadenylic acid (poly-A) as least efficient in this respect.
mesh_terms: D000227:Adenine Nucleotides / Q000528:radiation effects; D000818:Animals; D002645:Chickens; D003597:Cytosine Nucleotides / Q000528:radiation effects; D006150:Guanine Nucleotides / Q000528:radiation effects; D007292:Inosine Nucleotides / Q000528:radiation effects; D008027:Light; D009113:Muramidase / Q000528:radiation effects; D010179:Pancreas / Q000201:enzymology; D010777:Photochemistry; D011119:Polynucleotides / Q000528:radiation effects*; D011830:Radiation Effects; D012260:Ribonucleases / Q000528:radiation effects*; D012265:Ribonucleotides / Q000528:radiation effects; D012542:Scattering, Radiation; D014027:Tobacco Mosaic Virus / Q000528:radiation effects; D014500:Uracil Nucleotides / Q000528:radiation effects
chemical_list: D000227:Adenine Nucleotides; D003597:Cytosine Nucleotides; D006150:Guanine Nucleotides; D007292:Inosine Nucleotides; D011119:Polynucleotides; D012265:Ribonucleotides; D014500:Uracil Nucleotides; D012260:Ribonucleases; D009113:Muramidase