Cytological identification of the chromosomes involved in Searle's translocation and the location of the centromere in the X chromosome of the mouse.
The autosome in Searle's X-autosome translocation has been shown to be chromosome 16. The breakpoint in chromosome 16 is slightly proximal to the middle and in the X is slightly distal to the middle.-Available evidence indicates that either Linkage Group XV or Linkage Group XIX is carried on chromosome 16.-The centromere of the X chromosome is at the spf end of the linkage group.
D000818:Animals; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D003078:Colchicine; D003720:Densitometry; D008040:Genetic Linkage; D007621:Karyotyping; D051379:Mice; D008856:Microscopy, Fluorescence; D009150:Mustard Compounds; D011796:Quinacrine; D012730:Sex Chromosomes
D009150:Mustard Compounds; D011796:Quinacrine; D003078:Colchicine