Preclinical pharmacologic investigations on 1-nitro-9-(dimethylaminopropylamino)-acridine and its N-oxide. I. Acute and subchronic activity.
D000166:Acridines / Q000008:administration & dosage / Q000494:pharmacology / Q000633:toxicity*; D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D002415:Cats; D002697:Chloral Hydrate / Q000494:pharmacology; D005260:Female; D005298:Fertility / Q000187:drug effects; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects; D007022:Hypotension / Q000139:chemically induced; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D007928:Lethal Dose 50; D008297:Male; D008744:Methylamines / Q000008:administration & dosage / Q000633:toxicity; D051379:Mice; D009130:Muscle, Smooth / Q000187:drug effects; D009574:Nitro Compounds / Q000008:administration & dosage / Q000633:toxicity; D010087:Oxides / Q000008:administration & dosage / Q000633:toxicity; D011437:Propylamines / Q000008:administration & dosage / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D012119:Respiration / Q000187:drug effects; D013874:Thiopental / Q000494:pharmacology; D001743:Urinary Bladder / Q000187:drug effects
D000166:Acridines; D000970:Antineoplastic Agents; D008744:Methylamines; D009574:Nitro Compounds; D010087:Oxides; D011437:Propylamines; D002697:Chloral Hydrate; D013874:Thiopental