title: Human prolactin: 24-hour pattern with increased release during sleep.
abstract: Human prolactin was measured in plasma by radioimmunoassay at 20 minute intervals for a 24-hour period in each of six normal adults, whose sleep-wake cycles were monitored polygraphically. A marked diurnal variation in plasma concentrations was demonstrated, with highest values during sleep; periods of episodic release occurred throughout the 24 hours.
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007456:Iodine Isotopes; D008297:Male; D011388:Prolactin / Q000097:blood*; D011863:Radioimmunoassay; D012737:Sex Factors; D012890:Sleep
chemical_list: D007456:Iodine Isotopes; D011388:Prolactin; D013006:Growth Hormone