Indole-3-acetic acid in human cerebrospinal fluid: identification and quantification by mass fragmentography.
Indole-3-acetic acid has been identified in human cerebrospinal fluid by the gas chromatographic-mass spectrometric technique called mass fragmentography. A specific and sensitive method for quantitative determination of indole-3-acetic acid down to 2 nanograms per milliliter of cerebrospinal fluid has been developed. Samples of cerebrospinal fluid from 24 patients with depression contained 6.1 +/- 3.1 (range 2.6 to 15.8) nanograms of indole-3-acetic acid per milliliter.
D002849:Chromatography, Gas; D003863:Depression / Q000134:cerebrospinal fluid; D006801:Humans; D007210:Indoleacetic Acids / Q000134:cerebrospinal fluid*; D013058:Mass Spectrometry; D008722:Methods
D007210:Indoleacetic Acids