Brain-associated stem cell antigen: an antigen shared by brain and hemopoietic stem cells.
There is an antigen on mouse brain tissue which is shared by the hemopoietic colony-forming unit or stem cell of the mouse. Treatment of bone marrow or fetal liver cells with anti-brain antisera inhibits expression of colony-forming units. The anti-stem cell antibody is not absorbed by thymus cells and thus can be distinguished from the anti-thymocyte antibody which these antisera also contain.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000941:Antigens; D000961:Antilymphocyte Serum; D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D001921:Brain / Q000276:immunology*; D002999:Clone Cells / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D006041:Goats / Q000276:immunology; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology
D000941:Antigens; D000961:Antilymphocyte Serum