A rapid automated screening technique for the detection of placental-like alkaline phosphatase in malignant disease.
An automated heat-stability procedure at 65 degrees C for the detection of heat-stable placental and placental-like alkaline phosphatase is described. Placental-like enzymes were found in the serum of three patients suffering from malignant disease and one of these is described in detail.
D000368:Aged; D000469:Alkaline Phosphatase / Q000032:analysis* / Q000097:blood; D000818:Animals; D001322:Autoanalysis; D001797:Blood Protein Electrophoresis; D001842:Bone and Bones / Q000201:enzymology; D002850:Chromatography, Gel; D006358:Hot Temperature; D006801:Humans; D007422:Intestines / Q000201:enzymology; D008110:Liver Extracts; D008297:Male; D009369:Neoplasms / Q000201:enzymology*; D010920:Placenta / Q000201:enzymology; D010924:Placental Extracts; D011817:Rabbits; D013997:Time Factors; D014020:Tissue Extracts
D008110:Liver Extracts; D010924:Placental Extracts; D014020:Tissue Extracts; D000469:Alkaline Phosphatase