Deamination of arabinosyladenine by adenosine deaminase and inhibition by arabinosyl-6-mercaptopurine.
D000225:Adenine / Q000378:metabolism / Q000627:therapeutic use; D000241:Adenosine / Q000378:metabolism; D000619:Aminohydrolases / Q000037:antagonists & inhibitors*; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000378:metabolism; D001089:Arabinose / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D002458:Cell Fractionation; D002460:Cell Line; D003641:Deamination; D004351:Drug Resistance; D005260:Female; D007939:Leukemia L1210 / Q000188:drug therapy / Q000201:enzymology / Q000378:metabolism*; D015122:Mercaptopurine / Q000494:pharmacology* / Q000627:therapeutic use; D051379:Mice; D008815:Mice, Inbred Strains; D009154:Mutation; D009705:Nucleosides / Q000378:metabolism* / Q000627:therapeutic use
D000903:Antibiotics, Antineoplastic; D009705:Nucleosides; D001089:Arabinose; D015122:Mercaptopurine; D000619:Aminohydrolases; D000225:Adenine; D000241:Adenosine