Hemin control of globin synthesis: action of an inhibitor formed in the absence of hemin on the reticulocyte cell-free system and its reversal by a ribosomal factor.
D000818:Animals; D001798:Blood Proteins / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology*; D002247:Carbon Isotopes; D002474:Cell-Free System; D002499:Centrifugation, Density Gradient; D011232:Chemical Precipitation; D002848:Chromatography, DEAE-Cellulose; D002852:Chromatography, Ion Exchange; D005914:Globins / Q000096:biosynthesis*; D006418:Heme / Q000494:pharmacology*; D006639:Histidine / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007532:Isoleucine / Q000378:metabolism; D007700:Kinetics; D007930:Leucine / Q000378:metabolism; D011189:Potassium Chloride; D011817:Rabbits; D012156:Reticulocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism; D014357:Trypsin
D001798:Blood Proteins; D002247:Carbon Isotopes; D007532:Isoleucine; D006418:Heme; D006639:Histidine; D011189:Potassium Chloride; D005914:Globins; D014357:Trypsin; D007930:Leucine