Analgesic nephropathy: removal of phenacetin from proprietary analgesics.
Since phenacetin was withdrawn from Askit Powders and Beecham's Powders in 1966 these preparations have declined in importance as a cause of analgesic nephropathy in Western Scotland. In most patients with analgesic nephropathy who persist in abuse of compound analgesics renal function continues to decline. The deterioration, however, is less rapid among those taking aspirin and caffeine mixtures than in those taking preparations which also contain phenacetin.
D000700:Analgesics / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects; D002110:Caffeine / Q000009:adverse effects; D003061:Codeine / Q000009:adverse effects; D004338:Drug Combinations; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000453:epidemiology; D010615:Phenacetin / Q000009:adverse effects*; D012606:Scotland; D012651:Self Medication; D019966:Substance-Related Disorders
D000700:Analgesics; D004338:Drug Combinations; D002110:Caffeine; D010615:Phenacetin; D001241:Aspirin; D003061:Codeine