Possible etiology of schizophrenia: progressive damage to the noradrenergic reward system by endogenous 6-hydroxydopamine.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001921:Brain / Q000378:metabolism*; D002746:Chlorpromazine / Q000378:metabolism / Q000627:therapeutic use; D003216:Conditioning, Operant; D004298:Dopamine / Q000378:metabolism*; D004299:Dopamine beta-Hydroxylase / Q000378:metabolism; D006801:Humans; D009411:Nerve Endings / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D012201:Reward; D012559:Schizophrenia / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D012653:Self Stimulation / Q000187:drug effects
D004299:Dopamine beta-Hydroxylase; D002746:Chlorpromazine; D004298:Dopamine; D009638:Norepinephrine