title: Role of drug metabolism in drug research and development: importance of drug metabolism in clinical pharmacological evaluation of new drugs.
mesh_terms: D000284:Administration, Oral; D000661:Amphetamine / Q000097:blood; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D001702:Biopharmaceutics; D002073:Butanes / Q000097:blood; D002746:Chlorpromazine / Q000494:pharmacology; D004285:Dogs; D013759:Dronabinol / Q000008:administration & dosage / Q000097:blood / Q000652:urine; D005243:Feces / Q000032:analysis; D006168:Guinea Pigs; D006207:Half-Life; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D007275:Injections, Intravenous; D007700:Kinetics; D008729:Methoxamine / Q000097:blood; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D012106:Research; D013045:Species Specificity; D014316:Tritium
chemical_list: D001639:Bicarbonates; D002073:Butanes; D004364:Pharmaceutical Preparations; D014316:Tritium; D013759:Dronabinol; D000661:Amphetamine; D008729:Methoxamine; D006220:Haloperidol; D002746:Chlorpromazine