title: Centric fusion and trisomy for the LDH-B locus in brook trout, Salvelinus fontinalis.
abstract: Cytogenetic analyses showed that a trisomic male brook trout of genotype BB'B'' for one of the lactate dehydrogenase subunit loci had a karyotype with two extra arms appearing as a metacentric chromosome. The metacentric chromosome probably arose through centric fusion of two acrocentric or telocentric chromosomes-one of which carried the locus for subunit B-followed by nondisjunction.
mesh_terms: D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D005796:Genes; D005838:Genotype; D005880:Gills / Q000166:cytology; D007621:Karyotyping; D007668:Kidney / Q000166:cytology; D007770:L-Lactate Dehydrogenase / Q000096:biosynthesis; D012487:Salmonidae; D014314:Trisomy
chemical_list: D007770:L-Lactate Dehydrogenase