Duodenal involvement in Gardner's syndrome.
It is suggested that duodenal polyps are more frequent in Gardner's syndrome than previously recognized. The polyps have a particular tendency to undergo malignant change. Two patients with Gardner's syndrome are reported in whom duodenal polyps were associated in one patient with periampullary cancer and in the other with a possible adenocarcinoma of the duodenum.
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology; D000328:Adult; D014670:Ampulla of Vater; D001859:Bone Neoplasms / Q000150:complications; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D004379:Duodenal Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000150:complications / Q000000981:diagnostic imaging / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications*; D010018:Osteomalacia / Q000235:genetics*; D011859:Radiography; D012878:Skin Neoplasms / Q000150:complications*; D013577:Syndrome