The significance of lymphocytic infiltration in neuroblastoma.
A study of the significance of lymphocytic infiltration was made in a retrospective series of 23 primary neuroblastomata. The degree of lymphocytic infiltration was estimated and scored in 5 categories. Non-parametric rank order statistical methods were used to establish quantitative correlations, particularly with the duration of survival. A significant positive correlation was found both in infancy and childhood. It was found, unexpectedly, that the presence of metastases did not invalidate the correlation between lymphocyte score and survival.
D000293:Adolescent; D000704:Analysis of Variance; D002452:Cell Count; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008214:Lymphocytes; D008297:Male; D008433:Mathematics; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000473:pathology*; D011379:Prognosis; D013223:Statistics as Topic