Positive chronotropic and inotropic actions of new antitumor agent adriamycin and its cardiotoxicity--its special references to myocardial contractile force and the change of the transmembrane action potential.
D000200:Action Potentials / Q000187:drug effects*; D000606:Amino Sugars / Q000009:adverse effects / Q000494:pharmacology; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D003630:Daunorubicin / Q000037:antagonists & inhibitors / Q000494:pharmacology; D004558:Electric Stimulation; D006027:Glycosides / Q000009:adverse effects / Q000494:pharmacology*; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009279:Naphthacenes / Q000009:adverse effects / Q000494:pharmacology*; D010477:Perfusion; D011433:Propranolol / Q000494:pharmacology; D013268:Stimulation, Chemical
D000606:Amino Sugars; D000903:Antibiotics, Antineoplastic; D006027:Glycosides; D009279:Naphthacenes; D011433:Propranolol; D003630:Daunorubicin