Deficient folate activity during treatment of psoriasis with methotrexate diagnosed by determination of serine synthesis in lymphocytes.
D000328:Adult; D000368:Aged; D002247:Carbon Isotopes; D005260:Female; D005494:Folic Acid Deficiency / Q000139:chemically induced / Q000175:diagnosis*; D005561:Formates / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy* / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis; D012694:Serine / Q000096:biosynthesis*; D014805:Vitamin B 12 / Q000097:blood / Q000378:metabolism
D002247:Carbon Isotopes; D005561:Formates; D012694:Serine; D012313:RNA; D014805:Vitamin B 12; D008727:Methotrexate