The effect of lithium salts on the urinary excretion of  -oxoglutarate in man.
1. Lithium ions in therapeutic doses cause an increase in the renal excretion of alpha-oxoglutarate and glutaric acid.2. The excretion is probably due to reduced renal tubular reabsorption.3. Neither citrate, lactate nor pyruvate excretion rises.
D001714:Bipolar Disorder / Q000188:drug therapy / Q000652:urine; D002951:Citrates / Q000652:urine; D005977:Glutarates / Q000652:urine*; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism; D008094:Lithium / Q000494:pharmacology* / Q000627:therapeutic use; D011773:Pyruvates / Q000652:urine
D002951:Citrates; D005977:Glutarates; D011773:Pyruvates; D008094:Lithium