Effect of propranolol on gastric acid secretion in rats.
The effect of propranolol, a beta-adrenoceptor blocking agent, has been investigated on gastric acid secretion in pylorus and cardiac-ligated rats. Compared to the control group, propranolol significantly diminished the gastric acid secretion, and inhibited the formation of gastric ulceration.
D000818:Animals; D005750:Gastric Juice / Q000378:metabolism*; D008297:Male; D011433:Propranolol / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013276:Stomach Ulcer / Q000517:prevention & control
D011433:Propranolol