title: Evidence for the neutral hypothesis of protein polymorphism.
abstract: Data for some 400 polymorphic proteins were examined with special reference to molecular evolution, by using a statistic that depends on neither mutation rate, population structure, nor other ecological factors. The result indicates that most of these polymorphisms are maintained in a population by mutation and random genetic drift.
mesh_terms: D000483:Alleles; D004586:Electrophoresis; D005787:Gene Frequency; D005796:Genes; D006579:Heterozygote; D008433:Mathematics; D009154:Mutation; D011110:Polymorphism, Genetic; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis
chemical_list: D011506:Proteins