Demonstration that large metastases in lymph nodes disseminate cancer cells to blood and lungs.
D000671:Amputation, Surgical; D000818:Animals; D004195:Disease Models, Animal; D006614:Hindlimb; D008175:Lung Neoplasms / Q000503:physiopathology*; D008207:Lymphatic Metastasis / Q000503:physiopathology*; D051379:Mice; D009368:Neoplasm Transplantation; D009360:Neoplastic Cells, Circulating / Q000503:physiopathology*; D012513:Sarcoma, Experimental / Q000503:physiopathology*