title: Endogenous creatinine clearance as a clinical measure of glomerular filtration rate.
abstract: Endogenous creatinine clearance was assessed by inulin in 91 simultaneous studies in 41 patients and proved an accurate measurement of glomerular filtration rate. For filtration rates <20 ml/min the creatinine clearance may slightly overestimate the glomerular filtration rate. Successive determinations of filtration rate by either method may vary by 20% even though the methods agree with each other. Glomerular filtration rate itself is variable, and in its clinical usage this should be recognized.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003404:Creatinine / Q000378:metabolism* / Q000652:urine; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007444:Inulin / Q000097:blood / Q000652:urine; D007674:Kidney Diseases / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
chemical_list: D007444:Inulin; D003404:Creatinine