Uptake of gallium-67 in colonic and rectal tumours.
The uptake of (67)Ga in biopsy specimens of normal and abnormal tissue was measured in 20 cases of colonic and rectal disease and the ratio between the (67)Ga uptake in these diseases and in the normal colon or rectum was determined. Uptake of the isotope was high in most of the 14 primary malignant tumours, being highest in poorly differentiated tumours. This uptake was found to be concentrated at the active tumour edge. Uptake of the isotope was generally low in non-malignant lesions.
D001706:Biopsy; D003093:Colitis, Ulcerative / Q000175:diagnosis; D003106:Colon / Q000378:metabolism; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000378:metabolism*; D004241:Diverticulum, Colon / Q000378:metabolism; D005708:Gallium / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007417:Intestinal Polyps / Q000378:metabolism; D009362:Neoplasm Metastasis; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012004:Rectal Neoplasms / Q000378:metabolism*; D012007:Rectum / Q000378:metabolism
D011868:Radioisotopes; D005708:Gallium