The effects of humoral agents on the myoelectrical activity of the terminal ileum.
Electrical and motor activities of the terminal ileum have been recorded in 25 patients with a permanent ileostomy. Records made within a week of formation of the ileostomy show an increased motor activity which is significantly reduced after four weeks. Intravenous infusion of gastrin, 1 mug/kg-hr, was accompanied by a significant increase in action potentials and in the percentage motility. Conversely, secretin 1 unit/kg-hr was associated with a decrease in action potentials and in percentage motor activity.
D000200:Action Potentials / Q000187:drug effects; D005755:Gastrins / Q000494:pharmacology*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D007081:Ileostomy; D007082:Ileum / Q000187:drug effects*; D012633:Secretin / Q000494:pharmacology*; D013268:Stimulation, Chemical
D005755:Gastrins; D012633:Secretin