Failure of the biguanides to improve the control of unstable diabetes treated with insulin.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001645:Biguanides / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000188:drug therapy*; D004357:Drug Synergism; D005260:Female; D006029:Glycosuria / Q000175:diagnosis; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D001645:Biguanides; D007328:Insulin