The influence of the intracellular concentration of sodium on the uptake of L-( 14 C)valine by chopped tissue from cerebral cortex.
1. The intracellular concentrations of sodium, potassium, ATP and creatine phosphate in chopped tissue from guinea-pig cerebral cortex were altered by a 10min period of electrical stimulation. 2. The ability of the tissue to take up l-[(14)C]valine and incorporate it into protein was tested at various times after the cessation of electrical stimulation. 3. The restoration of the ability of the tissue to accumulate l-[(14)C]valine correlated closely with the restoration of the resting intracellular concentrations of sodium and ATP.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002247:Carbon Isotopes; D002540:Cerebral Cortex / Q000378:metabolism*; D004558:Electric Stimulation; D006168:Guinea Pigs; D066298:In Vitro Techniques; D010725:Phosphocreatine / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*; D013997:Time Factors; D014633:Valine / Q000378:metabolism*
D002247:Carbon Isotopes; D011506:Proteins; D010725:Phosphocreatine; D000255:Adenosine Triphosphate; D012964:Sodium; D014633:Valine; D011188:Potassium