A model system for the study of heteroexchange diffusion: methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells.
D000818:Animals; D001665:Binding Sites; D001692:Biological Transport / Q000187:drug effects; D002247:Carbon Isotopes; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D002848:Chromatography, DEAE-Cellulose; D004058:Diffusion; D005492:Folic Acid / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D005493:Folic Acid Antagonists; D005561:Formates / Q000494:pharmacology; D007700:Kinetics; D007939:Leukemia L1210 / Q000378:metabolism*; D008727:Methotrexate / Q000378:metabolism* / Q000494:pharmacology; D008745:Methylation; D051379:Mice; D008954:Models, Biological; D014316:Tritium
D002247:Carbon Isotopes; D005493:Folic Acid Antagonists; D005561:Formates; D014316:Tritium; D005492:Folic Acid; D008727:Methotrexate