Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.
D000208:Acute Disease; D000596:Amino Acids / Q000652:urine; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001202:Ascitic Fluid; D002247:Carbon Isotopes; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis; D005561:Formates / Q000378:metabolism; D006639:Histidine / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007938:Leukemia / Q000378:metabolism; D007939:Leukemia L1210 / Q000378:metabolism; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D009369:Neoplasms / Q000378:metabolism; D009603:Nitroso Compounds / Q000494:pharmacology; D011687:Purines / Q000096:biosynthesis*; D012313:RNA / Q000096:biosynthesis; D012694:Serine / Q000378:metabolism; D013941:Thymine / Q000096:biosynthesis; D014166:Transferases; D014508:Urea / Q000494:pharmacology*
D000596:Amino Acids; D000970:Antineoplastic Agents; D002247:Carbon Isotopes; D005561:Formates; D009603:Nitroso Compounds; D011687:Purines; D012694:Serine; D006639:Histidine; D012313:RNA; D014508:Urea; D004247:DNA; D014166:Transferases; D013941:Thymine