Intestinal secretion: stimulation by peptides.
Two peptides isolated from intestinal mucosa, vasoactive intestinal peptide, and gastric inhibitory peptide, stimulate small intestinal secretion in conscious dogs. Glucagon and pentagastrin also stimulate, but secretin and the octapetide of cholecystokinin do not. The stimulants may participate in regulation of intestinal secretion in health and in diseases with excessive secretion.
D000818:Animals; D001639:Bicarbonates / Q000032:analysis; D002712:Chlorides / Q000032:analysis; D002766:Cholecystokinin / Q000494:pharmacology; D004285:Dogs; D005755:Gastrins / Q000494:pharmacology; D005934:Glucagon / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D007263:Infusions, Parenteral; D007413:Intestinal Mucosa / Q000032:analysis / Q000187:drug effects*; D007419:Intestinal Secretions / Q000032:analysis / Q000187:drug effects*; D007583:Jejunum / Q000187:drug effects; D010455:Peptides / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D011188:Potassium / Q000032:analysis; D012633:Secretin / Q000494:pharmacology; D012964:Sodium / Q000032:analysis; D013268:Stimulation, Chemical
D001639:Bicarbonates; D002712:Chlorides; D005755:Gastrins; D010455:Peptides; D012633:Secretin; D005934:Glucagon; D002766:Cholecystokinin; D012964:Sodium; D011188:Potassium