title: Irreversible preneoplastic defect in alkaline phosphatase in cancerization of transitional epithelium.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D000478:Alkylation; D000818:Animals; D002471:Cell Transformation, Neoplastic; D003581:Cytodiagnosis; D004247:DNA / Q000378:metabolism; D004790:Enzyme Induction; D004847:Epithelial Cells; D004848:Epithelium / Q000201:enzymology / Q000473:pathology*; D009024:Morphogenesis; D009374:Neoplasms, Experimental; D009602:Nitrosamines / Q000494:pharmacology; D010212:Papilloma / Q000201:enzymology / Q000473:pathology; D051381:Rats; D001743:Urinary Bladder / Q000201:enzymology; D001749:Urinary Bladder Neoplasms / Q000201:enzymology / Q000473:pathology
chemical_list: D009602:Nitrosamines; D004247:DNA; D000469:Alkaline Phosphatase