Beta-propiolactone as an agent for enzyme sterilization.
A chemical method for the sterilization of pancreatin and trypsin is given. Evidence is presented to show that this treatment does not diminish the specific activity of the enzymes and has some advantages in microbiological techniques.
D004356:Drug Storage; D006571:Heterocyclic Compounds; D007783:Lactones; D010194:Pancreatin / Q000302:isolation & purification*; D013242:Sterilization; D014357:Trypsin / Q000302:isolation & purification*
D006571:Heterocyclic Compounds; D007783:Lactones; D010194:Pancreatin; D014357:Trypsin