Microtubule protein. Identification in and transport to nerve endings.
The subunit protein of microtubules, tubulin, has been demonstrated to be present in isolated nerve endings by gel electrophoresis, amino acid composition, and peptide mapping. The tubulin constitutes approximately 28% of the soluble protein of the nerve endings. The transport of tubulin to the nerve endings has been demonstrated and its relationship to slow transport is discussed.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001692:Biological Transport; D001921:Brain / Q000378:metabolism; D002458:Cell Fractionation; D002855:Chromatography, Thin Layer; D004589:Electrophoresis, Disc; D006651:Histocytochemistry; D007930:Leucine / Q000378:metabolism; D051379:Mice; D008854:Microscopy, Electron; D008870:Microtubules / Q000032:analysis*; D009411:Nerve Endings / Q000166:cytology* / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000378:metabolism; D009454:Neurofibrils; D010455:Peptides / Q000032:analysis; D013997:Time Factors; D014316:Tritium; D014747:Vinblastine
D000596:Amino Acids; D009419:Nerve Tissue Proteins; D010455:Peptides; D014316:Tritium; D014747:Vinblastine; D007930:Leucine