Mechanical properties of dystrophic mouse muscle.
A physiological method of estimating the number of motor units in normal and dystrophic muscles has revealed a large reduction in the number of motor units in dystrophic muscles. Anatomical confirmation of the results has been obtained. Dystrophic muscles also exhibit a `myasthenic-like' response to high frequency stimulation. It is suggested that the nerve fibre is primarily affected in murine dystrophy.
D000200:Action Potentials; D000818:Animals; D001696:Biomechanical Phenomena; D001835:Body Weight; D004558:Electric Stimulation; D051379:Mice; D009046:Motor Neurons; D009119:Muscle Contraction; D009132:Muscles / Q000294:innervation / Q000473:pathology / Q000503:physiopathology*; D009137:Muscular Dystrophy, Animal / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D009469:Neuromuscular Junction; D009929:Organ Size; D011930:Reaction Time; D012584:Sciatic Nerve / Q000473:pathology / Q000503:physiopathology; D013977:Tibia