Inhibition of the amidase and kininogenase activities of pancreatic kallikrein by aromatic diamidines and an evaluation of diamidines for their in vivo use.
D000578:Amidines / Q000494:pharmacology*; D000581:Amidohydrolases / Q000037:antagonists & inhibitors*; D000813:Anilides; D000818:Animals; D001780:Blood Coagulation Tests; D001794:Blood Pressure / Q000187:drug effects; D004285:Dogs; D004336:Drug Antagonism; D005260:Female; D006494:Heparin Antagonists; D006868:Hydrolysis; D007022:Hypotension / Q000139:chemically induced; D007610:Kallikreins / Q000037:antagonists & inhibitors*; D010179:Pancreas / Q000201:enzymology; D010617:Phenanthridines / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013552:Swine; D013925:Thromboplastin; D014048:Tolonium Chloride
D000578:Amidines; D000813:Anilides; D006494:Heparin Antagonists; D010617:Phenanthridines; D014048:Tolonium Chloride; D013925:Thromboplastin; D007610:Kallikreins; D000581:Amidohydrolases