Selective recovery from retrograde amnesia produced by hippocampal spreading depression.
Injections of potassium chloride into the hippocampus after learning produce temporary disruption of neural activity and retrograde amnesia. Recovery from the amnesia is selective-rats recover from amnesia of events that occurred24 hours before injection but do not recover from amnesia of events that occurred 10 seconds before injection.
D000647:Amnesia; D000818:Animals; D001921:Brain / Q000187:drug effects; D003213:Conditioning, Psychological; D004327:Drinking Behavior; D004569:Electroencephalography; D004597:Electroshock; D006624:Hippocampus / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007267:Injections; D008297:Male; D008568:Memory / Q000187:drug effects; D011189:Potassium Chloride / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012965:Sodium Chloride / Q000494:pharmacology; D013997:Time Factors
D012965:Sodium Chloride; D011189:Potassium Chloride