title: The effect of spironolactone on drug metabolism by hepatic microsomes.
mesh_terms: D000315:Adrenalectomy; D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism; D002369:Castration; D003580:Cytochromes; D003640:Dealkylation; D004579:Electron Transport; D004790:Enzyme Induction; D005260:Female; D006591:Hexobarbital / Q000378:metabolism; D006900:Hydroxylation; D007700:Kinetics; D008297:Male; D008777:Methyltestosterone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D009019:Morphinans / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D051381:Rats; D012737:Sex Factors; D012890:Sleep; D013148:Spironolactone / Q000494:pharmacology*
chemical_list: D001580:Benzopyrenes; D003580:Cytochromes; D009019:Morphinans; D004364:Pharmaceutical Preparations; D013148:Spironolactone; D006591:Hexobarbital; D010088:Oxidoreductases; D008777:Methyltestosterone