title: Specificity in enzyme inhibition. 1. Synthesis of 4-(4-imidazolyl)-3-amino-2-butanone, 4-(4-imidazolyl)-3-acetamido-2-butanone, and 4-(4-imidazolylmethyl)-2,5-dimethyloxazole for assay as inhibitors of histidine decarboxylase.
mesh_terms: D000818:Animals; D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001665:Binding Sites; D002074:Butanones / Q000138:chemical synthesis / Q000494:pharmacology*; D002247:Carbon Isotopes; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors*; D005333:Fetus / Q000201:enzymology; D006168:Guinea Pigs; D006639:Histidine; D007093:Imidazoles / Q000138:chemical synthesis / Q000494:pharmacology*; D007668:Kidney / Q000201:enzymology; D010080:Oxazoles / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D011955:Receptors, Drug
chemical_list: D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D002074:Butanones; D002247:Carbon Isotopes; D007093:Imidazoles; D010080:Oxazoles; D011955:Receptors, Drug; D006639:Histidine; D002262:Carboxy-Lyases