Herpesvirus type 2 isolated from cervical tumor cells grown in tissue culture.
A herpesvirus has been isolated from spontaneously degenerating cultures of cervical tumor cells grown in vitro. The virus was identified as a type 2 herpesvirus on the basis of biologic properties, including plaque morphology and microtubule formation in infected HEp-2 cells, and of immunologic specificity as determined by neutralization. Herpesvirus antigens and virus particles were not seen in duplicate cultures of viable cervical tumor cells.
D000956:Antigens, Viral / Q000032:analysis; D002277:Carcinoma / Q000382:microbiology* / Q000473:pathology; D002478:Cells, Cultured; D005260:Female; D006564:Herpesviridae / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008854:Microscopy, Electron; D009500:Neutralization Tests; D002583:Uterine Cervical Neoplasms / Q000382:microbiology* / Q000473:pathology; D014776:Virus Cultivation
D000956:Antigens, Viral