Nonconversion of o,p'-DDT to p,p'-DDT in rats, sheep, chickens, and quail.
The finding of appreciable quantities of p,p'-DDT after feeding o,p'-DDT to rats led to the proposal of a theory, that an isomeric metabolic conversion occurs. The presence of p,p'-DDT as an impurity in supposedly pure samples of o,p'-DDT is the correct explanation for the appearance of p,p'-DDT. Purified o,p'-DDT and (14)C-labeled o,p'-DDT yielded no data to support the idea that o,p'-DDT is converted to the p,p'-DDT isomer.
D000273:Adipose Tissue / Q000032:analysis; D000818:Animals; D001345:Autoradiography; D001711:Biotransformation; D001717:Birds; D002247:Carbon Isotopes; D002645:Chickens; D002855:Chromatography, Thin Layer; D003634:DDT / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D004032:Diet; D005260:Female; D051381:Rats; D012756:Sheep
D002247:Carbon Isotopes; D003634:DDT