Retention deficit correlated with a deficit in the corticoid response to stress.
Previous research has indicated that intracerebral injection of potassium chloride, and the resultant electrical silence of the brain, lead to the attenuation of a previously conditioned emotional response; this response may reflect conditioned fear. The data reported here indicate that the normal mobilization of corticosteroids, perhaps a second index of emotionality, is also attenuated by such injections.
D000311:Adrenal Glands / Q000032:analysis; D000818:Animals; D001921:Brain / Q000187:drug effects*; D003213:Conditioning, Psychological; D003345:Corticosterone / Q000097:blood / Q000378:metabolism*; D004569:Electroencephalography; D004597:Electroshock; D005239:Fear / Q000187:drug effects*; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D007267:Injections; D008297:Male; D011189:Potassium Chloride / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D013315:Stress, Psychological / Q000378:metabolism*
D011189:Potassium Chloride; D003345:Corticosterone