title: Scleroderma and the subcutaneous tissue.
abstract: Our study revealed that as observed with both light and electron microscopy the most specific abnormality in sclerodermna skin is the replacement of the subcutaneous tissue by markedly abnormal connective tissue.
mesh_terms: D000328:Adult; D000368:Aged; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000473:pathology*; D003680:Deglutition Disorders; D006801:Humans
chemical_list: D003094:Collagen