Cell dissociation: univalent antibodies as a possible alternative to proteolytic enzymes.
Univalent antibody fragments directed against special membrane antigens dissociate multicellular bodies of the cellular slime mold Dictyostelium discoideum completely into single cells. This provides a gentle method for cell dissociation and demonstrates that a nonenzyme protein can disintegrate a tissue
D000818:Animals; D000906:Antibodies; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions; D002448:Cell Adhesion; D003585:Cell Biology; D002462:Cell Membrane / Q000276:immunology; D009235:Myxomycetes / Q000166:cytology / Q000276:immunology; D011817:Rabbits
D000906:Antibodies