Hydroxylation and subsequent glucuronide conjugation of desmethylimipramine in rat liver microsomes.
D000818:Animals; D003580:Cytochromes / Q000378:metabolism; D003891:Desipramine / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005965:Glucuronates / Q000008:administration & dosage / Q000378:metabolism*; D006900:Hydroxylation; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013057:Spectrum Analysis; D014316:Tritium; D014500:Uracil Nucleotides / Q000008:administration & dosage / Q000378:metabolism
D003580:Cytochromes; D005965:Glucuronates; D014500:Uracil Nucleotides; D014316:Tritium; D011335:Proadifen; D003891:Desipramine