A novel mechanism for the inhibition of DNA synthesis following methylation: the effect of N-methyl-N-nitrosourea on HeLa cells.
D000478:Alkylation; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D006224:Cricetinae; D004247:DNA / Q000096:biosynthesis*; D004260:DNA Repair / Q000187:drug effects; D004261:DNA Replication / Q000187:drug effects; D006367:HeLa Cells / Q000187:drug effects*; D007700:Kinetics; D008745:Methylation; D008954:Models, Biological; D009603:Nitroso Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D009607:Nitrosourea Compounds; D014176:Protein Biosynthesis; D013997:Time Factors; D014316:Tritium; D014508:Urea / Q000008:administration & dosage / Q000494:pharmacology*
D009603:Nitroso Compounds; D009607:Nitrosourea Compounds; D014316:Tritium; D014508:Urea; D004247:DNA