title: Induction and repression of microsomal drug-metabolizing enzymes by polycyclic hydrocarbons and phenobarbital: theoretical models.
mesh_terms: D000494:Allosteric Regulation / Q000187:drug effects; D000818:Animals; D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D001580:Benzopyrenes / Q000494:pharmacology; D002706:Chlordan / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects*; D004794:Enzyme Repression / Q000187:drug effects*; D005001:Ethionine / Q000494:pharmacology; D005449:Fluorenes / Q000494:pharmacology; D005809:Genes, Regulator; D006591:Hexobarbital / Q000494:pharmacology; D008614:Meperidine / Q000494:pharmacology; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D008954:Models, Biological; D009876:Operon / Q000187:drug effects; D010088:Oxidoreductases / Q000096:biosynthesis; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats; D015049:Zoxazolamine / Q000494:pharmacology
chemical_list: D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D005449:Fluorenes; D002706:Chlordan; D008748:Methylcholanthrene; D015049:Zoxazolamine; D008614:Meperidine; D006591:Hexobarbital; D010088:Oxidoreductases; D005001:Ethionine; D010634:Phenobarbital