Imidazole-catalyzed displacement of an amine from an amide by a neighboring hydroxyl group. A model for the acylation of chymotrypsin.
D000215:Acylation; D000577:Amides; D000588:Amines; D002384:Catalysis; D002918:Chymotrypsin; D006900:Hydroxylation; D007093:Imidazoles; D008956:Models, Chemical; D010447:Peptide Hydrolases; D012694:Serine
D000577:Amides; D000588:Amines; D007093:Imidazoles; D012694:Serine; D010447:Peptide Hydrolases; D002918:Chymotrypsin