title: Ascorbic acid status in iron-deficiency anaemia.
abstract: Leucocyte ascorbic acid concentration declines with age. Patients with iron-deficiency anaemia have higher concentrations than normal while those with iron overload have a reduced concentration. It is suggested that these phenomena may be a result of reduced ascorbate catabolism in iron-deficiency anaemia and they provide support for the suggestion that the amount of iron in the tissues may be an important factor in determining ascorbic acid utilization.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000747:Anemia, Hypochromic / Q000097:blood* / Q000378:metabolism; D001205:Ascorbic Acid / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood / Q000378:metabolism; D007962:Leukocytes / Q000378:metabolism; D008297:Male; D008875:Middle Aged
chemical_list: D007501:Iron; D001205:Ascorbic Acid