The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions.
D000083:Acetanilides / Q000378:metabolism; D000632:Aminopyrine / Q000378:metabolism; D000818:Animals; D001665:Binding Sites / Q000187:drug effects*; D003061:Codeine / Q000378:metabolism; D003580:Cytochromes / Q000378:metabolism*; D006591:Hexobarbital / Q000378:metabolism; D008797:Metyrapone / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000201:enzymology*; D009019:Morphinans / Q000378:metabolism; D009596:Nitrophenols / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D013057:Spectrum Analysis
D000083:Acetanilides; D003580:Cytochromes; D009019:Morphinans; D009596:Nitrophenols; D000632:Aminopyrine; D006591:Hexobarbital; D003061:Codeine; D008797:Metyrapone