title: Effects of methotrexate on the synthesis and properties of dihydrofolate reductases in rat liver.
mesh_terms: D000818:Animals; D002850:Chromatography, Gel; D004351:Drug Resistance; D004586:Electrophoresis; D005493:Folic Acid Antagonists; D007527:Isoenzymes / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000096:biosynthesis / Q000302:isolation & purification; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D008727:Methotrexate / Q000494:pharmacology*; D008970:Molecular Weight; D051381:Rats; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis / Q000096:biosynthesis / Q000302:isolation & purification
chemical_list: D005493:Folic Acid Antagonists; D007527:Isoenzymes; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate