title: Responses to pressor substances in conscious and anaesthetized cats.
abstract: The blood pressure responses to intravenous injections of noradrenaline, tyramine and McN-A-343 have been determined in conscious cats and in cats under pentobarbitone sodium, alpha-chloralose, urethane or alpha-chloralose plus urethane anaesthesia. All four anaesthetic agents reduced the pressor responses, the reduction being most pronounced with urethane and least pronounced with alpha-chloralose. Pentobarbitone sodium exerted a greater inhibitory effect on the responses to McN-A-343 than on those to noradrenaline or tyramine.
mesh_terms: D000768:Anesthesia, General; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002219:Carbamates / Q000494:pharmacology; D002319:Cardiovascular System / Q000187:drug effects; D002415:Cats; D002698:Chloralose / Q000494:pharmacology; D003243:Consciousness; D009638:Norepinephrine / Q000494:pharmacology; D010424:Pentobarbital / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D014439:Tyramine / Q000494:pharmacology; D014520:Urethane / Q000494:pharmacology
chemical_list: D002219:Carbamates; D000644:Quaternary Ammonium Compounds; D002698:Chloralose; D014520:Urethane; D010424:Pentobarbital; D009638:Norepinephrine; D014439:Tyramine