Stevens-Johnson syndrome following anticonvulsant therapy in penetrating head injury.
Five cases of Stevens-Johnson syndrome are described in patients with penetrating head wounds who were treated with Penicillin, streptomycin, sulphadiazine and the anticonvulsant drugs, epanutin and phenobarbitone. One patient who continued to have only his anticonvulsants after the appearance of his skin eruption, died. In two other cases, epanutin and phenobarbiton each was responsible for the Stevens-Johnson syndrome.
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D006259:Craniocerebral Trauma / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D010634:Phenobarbital / Q000009:adverse effects / Q000627:therapeutic use; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced*; D014950:Wounds, Penetrating
D000927:Anticonvulsants; D010634:Phenobarbital