Substrate interaction with P-450 in the hydroxylation of drugs under abnormal physiological states.
D000311:Adrenal Glands / Q000502:physiology; D000315:Adrenalectomy; D000632:Aminopyrine / Q000378:metabolism; D000728:Androgens / Q000494:pharmacology; D000814:Aniline Compounds; D000818:Animals; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology; D005260:Female; D006591:Hexobarbital; D006900:Hydroxylation; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D009020:Morphine / Q000494:pharmacology; D051381:Rats; D012737:Sex Factors; D013053:Spectrophotometry; D013217:Starvation; D013961:Thyroid Gland / Q000502:physiology; D013965:Thyroidectomy; D013974:Thyroxine / Q000494:pharmacology; D015049:Zoxazolamine
D000728:Androgens; D000814:Aniline Compounds; D000632:Aminopyrine; D009020:Morphine; D003577:Cytochrome P-450 Enzyme System; D015049:Zoxazolamine; D006591:Hexobarbital; D013974:Thyroxine