Transformation of mammalian cells by crude histones.
A baby hamster kidney cell line (BHK21), maintained in the presence of crude histone preparations for 3 days, has been shown to undergo morphological and behavioural transformations similar in nature to those obtained with viruses and mycoplasmas.
D000818:Animals; D002417:Cattle; D002449:Cell Aggregation / Q000187:drug effects; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000139:chemically induced*; D006224:Cricetinae; D006657:Histones / Q000494:pharmacology*; D007668:Kidney; D008099:Liver; D010455:Peptides / Q000494:pharmacology; D051381:Rats; D013950:Thymus Gland
D006657:Histones; D010455:Peptides