Interference with the 5 -reductase system. A new approach for developing antiandrogens.
D000726:Androgen Antagonists; D000818:Animals; D002467:Cell Nucleus; D003345:Corticosterone / Q000494:pharmacology; D046508:Culture Techniques; D013196:Dihydrotestosterone / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology; D008297:Male; D010088:Oxidoreductases / Q000378:metabolism*; D010902:Pituitary Gland / Q000201:enzymology / Q000378:metabolism; D011374:Progesterone / Q000494:pharmacology; D011467:Prostate / Q000201:enzymology / Q000378:metabolism; D051381:Rats; D013739:Testosterone / Q000378:metabolism
D000726:Androgen Antagonists; D013196:Dihydrotestosterone; D013739:Testosterone; D011374:Progesterone; D010088:Oxidoreductases; D003345:Corticosterone; D006854:Hydrocortisone