Biochemical approaches to the study of muscle disease.
Several current approaches to the biochemistry of dystrophic muscle are reviewed with emphasis on the possible merits and limitations of each method.  General difficulties in the study of diseased muscle apply more or less to each of the approaches.  Data on dystrophic muscle obtained by technics developed for the study of normal muscle must be carefully assessed before reliable conclusions can be drawn
D000818:Animals; D001706:Biopsy / Q000009:adverse effects; D002118:Calcium / Q000378:metabolism; D002478:Cells, Cultured; D046508:Culture Techniques; D005347:Fibroblasts; D006019:Glycolysis; D006801:Humans; D007527:Isoenzymes / Q000172:deficiency; D051379:Mice; D009132:Muscles / Q000032:analysis / Q000201:enzymology / Q000378:metabolism*; D009135:Muscular Diseases / Q000201:enzymology / Q000378:metabolism*; D009136:Muscular Dystrophies / Q000209:etiology / Q000378:metabolism; D012107:Research Design / Q000592:standards
D007527:Isoenzymes; D002118:Calcium