Immunosuppression with cis-platinum (II) diamminodichloride: effect on antibody plaque-forming spleen cells.
A new antitumor compound, cis-platinum (II) diamminodichloride, suppressed antibody plaque-forming cells in C(3)H mice when given in a single dose of 10 mg per kg of body weight within 2 days before or after sensitization.
D000588:Amines / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology; D002712:Chlorides / Q000494:pharmacology; D004912:Erythrocytes / Q000276:immunology; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009929:Organ Size; D010984:Platinum / Q000008:administration & dosage / Q000494:pharmacology*; D012756:Sheep / Q000276:immunology; D013154:Spleen / Q000187:drug effects* / Q000276:immunology
D000588:Amines; D000970:Antineoplastic Agents; D002712:Chlorides; D007166:Immunosuppressive Agents; D010984:Platinum