Congenital goiter found in a district of Omuro, Kochi, Shikoku, Japan: familial goiter caused by possible defect of diiodotyrosine coupling to form thyroxine.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004105:Diiodotyrosine / Q000378:metabolism* / Q000652:urine; D005260:Female; D006042:Goiter / Q000151:congenital* / Q000209:etiology / Q000235:genetics / Q000378:metabolism; D006801:Humans; D007455:Iodine / Q000378:metabolism; D007456:Iodine Isotopes; D007621:Karyotyping; D008297:Male; D008659:Metabolic Diseases / Q000150:complications; D010375:Pedigree; D013861:Thiocyanates / Q000008:administration & dosage; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000378:metabolism; D013974:Thyroxine / Q000096:biosynthesis*; D014284:Triiodothyronine / Q000096:biosynthesis
D007456:Iodine Isotopes; D013861:Thiocyanates; D014284:Triiodothyronine; D004105:Diiodotyrosine; D007455:Iodine; D013974:Thyroxine