A new design for the screening of CNS-active drugs in mice. A multi-dimensional observation procedure and the study of pharmacological interactions.
D000661:Amphetamine / Q000037:antagonists & inhibitors; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology* / Q000633:toxicity; D000928:Antidepressive Agents / Q000494:pharmacology* / Q000633:toxicity; D004347:Drug Interactions; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D007928:Lethal Dose 50; D008297:Male; D008722:Methods; D051379:Mice; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D012110:Reserpine / Q000037:antagonists & inhibitors; D013331:Strychnine / Q000037:antagonists & inhibitors; D014149:Tranquilizing Agents / Q000494:pharmacology* / Q000633:toxicity; D014203:Tremorine / Q000037:antagonists & inhibitors
D000927:Anticonvulsants; D000928:Antidepressive Agents; D006993:Hypnotics and Sedatives; D009125:Muscle Relaxants, Central; D014149:Tranquilizing Agents; D012110:Reserpine; D000661:Amphetamine; D013331:Strychnine; D007099:Imipramine; D014203:Tremorine; D010433:Pentylenetetrazole