CHANDS: the curly hair-ankyloblepharon-nail dysplasia syndrome.
Reported here is an inbred family of Dutch extraction in which there appears to be both a "new" autosomal dominant trait (the combination of curly hair, ankyloblepharon and nail dysplasia) and an autosomal recessive trait (an ataxia). The ataxia, seemingly an extrapyramidal disorder, was encountered in three of nine sibs and will be the subject of a separate report.
D001259:Ataxia / Q000235:genetics*; D002675:Child, Preschool; D005143:Eyelids / Q000002:abnormalities*; D005260:Female; D005799:Genes, Dominant; D006197:Hair; D006801:Humans; D007223:Infant; D008297:Male; D009264:Nails, Malformed / Q000235:genetics*; D010375:Pedigree