Irreversible enzyme inhibitors. CXII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine substituted with a terminal sulfonyl fluoride. II.
D000588:Amines; D000818:Animals; D001555:Benzene Derivatives; D001665:Binding Sites; D002279:Carcinoma 256, Walker / Q000201:enzymology; D055598:Chemical Phenomena; D002621:Chemistry; D010856:Columbidae; D005461:Fluorine; D005493:Folic Acid Antagonists; D007939:Leukemia L1210 / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008722:Methods; D051379:Mice; D051381:Rats; D013424:Sulfanilamides / Q000494:pharmacology; D013451:Sulfonic Acids; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism; D014227:Triazines / Q000138:chemical synthesis / Q000494:pharmacology
D000588:Amines; D001555:Benzene Derivatives; D005493:Folic Acid Antagonists; D013424:Sulfanilamides; D013451:Sulfonic Acids; D014227:Triazines; D005461:Fluorine; D013762:Tetrahydrofolate Dehydrogenase