Interruption of the tryptophan-nicotinic acid pathway by penicillamine-induced pyridoxine deficiency in patients with Wilson's disease and in experimental animals.
D000818:Animals; D002247:Carbon Isotopes; D002845:Chromatography; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy / Q000378:metabolism* / Q000652:urine; D006801:Humans; D007737:Kynurenine / Q000378:metabolism; D008297:Male; D009539:Nicotinic Acids / Q000378:metabolism*; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use; D051381:Rats; D014364:Tryptophan / Q000378:metabolism*; D014556:Urine / Q000032:analysis; D026681:Vitamin B 6 Deficiency / Q000139:chemically induced / Q000378:metabolism*; D014977:Xanthurenates / Q000378:metabolism / Q000652:urine; D062367:ortho-Aminobenzoates / Q000378:metabolism
D002247:Carbon Isotopes; D009539:Nicotinic Acids; D014977:Xanthurenates; D062367:ortho-Aminobenzoates; D007737:Kynurenine; D014364:Tryptophan; D010396:Penicillamine