Unit activity in the isolated spinal cord of chick embryo, in situ.
Unit electrical activity was recorded from single neurons in the isolated lumbo-sacral spinal cord of 14- to 19-day chick embryos, in situ. Spinal cord transection was combined with transection of all lumbo-sacral dorsal roots. The spontaneous discharge of cells is confined, for the most part, to the lower two thirds of the cord. A quasilinear reduction in the number of spontaneously active units was found during the developmental period studied. Comparable results were obtained in decentralized cord with sensory inputs blocked by xylocaine.
D000818:Animals; D002642:Chick Embryo; D004566:Electrodes; D004594:Electrophysiology; D066298:In Vitro Techniques; D008012:Lidocaine / Q000494:pharmacology; D008161:Lumbosacral Region; D009474:Neurons / Q000502:physiology; D013116:Spinal Cord / Q000187:drug effects / Q000502:physiology*
D008012:Lidocaine