Enhanced immunogenicity of chemically-coated syngeneic tumor cells.
The immunogenicity of the EL-4 strain of mouse lymphoid leukemia cells in syngeneic C57BL/6 recipients was enhanced by in vitro coating of the cells with either Concanavalin A or dinitrophenylaminocaproate. The tumor-specific immune response was quantitated using a recently developed assay that involves in vitro cell-mediated cytotoxicity.
D000614:Aminocaproates / Q000494:pharmacology*; D000818:Animals; D000941:Antigens; D001201:Ascites; D001769:Blood / Q000276:immunology; D002460:Cell Line; D002859:Chromium Isotopes; D004140:Dinitrophenols / Q000494:pharmacology*
D000614:Aminocaproates; D000941:Antigens; D002859:Chromium Isotopes; D004140:Dinitrophenols