Dolichol monophosphate glucose: an intermediate in glucose transfer in liver.
The microsomal fraction of liver has been found to catalyze glucose transfer from UDPG to a lipid acceptor which appears to be identical to the compound obtained by chemical phosphorylation of dolichol. The substance formed (dolichol monophosphate glucose) is acid labile and yields 1,6-anhydroglucosan by alkaline treatment. It can be used as substrate by the enzyme system yielding a glucoprotein which is subsequently hydrolyzed to glucose.
D000438:Alcohols / Q000378:metabolism*; D000818:Animals; D002247:Carbon Isotopes; D002855:Chromatography, Thin Layer; D005947:Glucose / Q000378:metabolism*; D006023:Glycoproteins / Q000378:metabolism; D006600:Hexosephosphates / Q000378:metabolism*; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism*; D008862:Microsomes, Liver / Q000378:metabolism; D013552:Swine; D014500:Uracil Nucleotides / Q000378:metabolism
D000438:Alcohols; D002247:Carbon Isotopes; D006023:Glycoproteins; D006600:Hexosephosphates; D014500:Uracil Nucleotides; D005947:Glucose