Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts.
Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and transformed 3T3 cells in serum-free medium, probably without inducing growth of the cells. These factors are separated and partially purified.
D000818:Animals; D001769:Blood; D001797:Blood Protein Electrophoresis; D002471:Cell Transformation, Neoplastic; D003470:Culture Media; D003588:Cytopathogenic Effect, Viral
D003470:Culture Media