Nerve growth factor from cobra venom.
The chemical and biological properties of the nerve growth factor isolated from Naja naja venom are described. The nerve growth promoting activity appears to be distinct from the most commonly known enzymes and toxins present in the venom. The purified nerve growth factor from cobra venom has properties remarkably similar to those of the nerve growth factor isolated from mouse submaxillary gland. These findings are discussed in connection with the problem of the physiological function of this unique protein in the two species.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001681:Biological Assay; D002850:Chromatography, Gel; D046508:Culture Techniques; D004798:Enzymes / Q000032:analysis; D006133:Growth Substances / Q000302:isolation & purification*; D007122:Immunoelectrophoresis; D009414:Nerve Growth Factors / Q000302:isolation & purification; D011817:Rabbits; D012911:Snakes; D014461:Ultracentrifugation; D014688:Venoms / Q000032:analysis*
D000596:Amino Acids; D004798:Enzymes; D006133:Growth Substances; D009414:Nerve Growth Factors; D014688:Venoms