Mechanism of action of thrombin on fibrinogen. I. Synthesis of fibrinogen-like peptides, and their proteolysis by thrombin and trypsin.
In a study of the action of thrombin on fibrinogen and a comparison of this enzyme with trypsin, several fibrinogen-like oligopeptides were synthesized. The hydrolysis of the arginyl-glycine bond in these peptides, by both of these enzymes, is examined and compared.
D000595:Amino Acid Sequence; D000818:Animals; D001120:Arginine / Q000378:metabolism; D002417:Cattle; D002855:Chromatography, Thin Layer
D001120:Arginine