Clinical evaluation of Brinaldix. A new oral diuretic.
'Brinaldix', a new non-thiazide oral diuretic, has been used in a trial on three normal subjects and fourteen patients with oedema from various causes. It is a potent salidiuretic and proved superior to bendrofluazide in 10 out of 14 patients. It produced a substantial potassium diuresis, and we are of the opinion that potassium supplements should be given in conjunction with it. In one normal subject it produced a period of postural hypotension; no other major side-effects were noted.
D000328:Adult; D000368:Aged; D001539:Bendroflumethiazide / Q000627:therapeutic use; D055598:Chemical Phenomena; D002621:Chemistry; D002648:Child; D003005:Clopamide / Q000627:therapeutic use*; D004341:Drug Evaluation; D004487:Edema / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D003005:Clopamide; D001539:Bendroflumethiazide