Synthesis of an actinomycin analog with substituted lactone oxygens (1',1'-bis(L-,-diaminopropionic acid))-actinomycin C (C 1).
D000596:Amino Acids; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000627:therapeutic use; D001593:Benzyl Compounds; D055598:Chemical Phenomena; D002621:Chemistry; D003609:Dactinomycin / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D005561:Formates; D007769:Lactams / Q000138:chemical synthesis; D007778:Lactobacillus / Q000187:drug effects; D009578:Nitrobenzenes; D012516:Osteosarcoma / Q000188:drug therapy; D011422:Propionates; D051381:Rats; D012513:Sarcoma, Experimental / Q000188:drug therapy; D012694:Serine
D000596:Amino Acids; D000970:Antineoplastic Agents; D001593:Benzyl Compounds; D005561:Formates; D007769:Lactams; D009578:Nitrobenzenes; D011422:Propionates; D003609:Dactinomycin; D012694:Serine