Cells involved in the immune response. XVI. The response of immune rabbit cells to phytohemagglutinin, antigen, and goat anti-rabbit immunoglobulin antiserum.
There exists in the rabbit a population of lymphocytes carrying immunoglobulin-like receptors on their surface. These receptors interact with antigen and with anti-immunoglobulin antibodies and appear to mediate the recognition process leading to the humoral immune response. There exists in the rabbit a second population of lymphocytes capable of reacting with phytohemagglutinin. This population of lymphocytes is different from the one capable of reacting with soluble protein antigens or anti-immunoglobulin antiserum and is probably involved in the mediation of cellular immunity.
D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D000917:Antibody Formation; D000941:Antigens; D046508:Culture Techniques; D006041:Goats; D006801:Humans; D007106:Immune Sera; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D008221:Lymphoid Tissue / Q000276:immunology*; D011817:Rabbits; D012709:Serum Albumin; D013154:Spleen / Q000276:immunology; D014316:Tritium
D000888:Antibodies, Anti-Idiotypic; D000941:Antigens; D007106:Immune Sera; D012709:Serum Albumin; D014316:Tritium