Evaluation of selected drugs for the treatment of canine echinococcosis.
Results are reported from 26 trials of various drugs for the treatment of canine echinococcosis. In all, 613 dogs were employed. Arecoline hydrobromide and Anthelin, in single trials of each, failed to remove even half the E. granulosus worms in 50% of the dogs treated with these compounds. A total of 24 trials were carried out with a series of 8 naphthalene derivatives and compounds of this series were effective in eliminating E. granulosus; at least one of them, bunamidine hydrochloride, seems to show sufficient promise as an improved method of treatment for field application and evaluation trials to be made.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000662:veterinary*; D009281:Naphthalenes / Q000627:therapeutic use
D000871:Anthelmintics; D009281:Naphthalenes