Effect of antifungal compounds on aspergillosis in hatching chick embryos.
Aspergillosis was induced experimentally in hatching chick embryos by dipping them in water containing spores of Aspergillus fumigatus or A. flavus. The addition to the dip water of antifungal compounds prevented the development of this syndrome. Of the compounds studied, amphotericin B was most effective, followed by pimaricin and nystatin. Sorbic acid was without effect.
D000143:Acids / Q000494:pharmacology*; D000666:Amphotericin B / Q000494:pharmacology*; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001228:Aspergillosis / Q000188:drug therapy*; D001230:Aspergillus / Q000187:drug effects*; D002642:Chick Embryo; D003902:Detergents / Q000494:pharmacology*; D010866:Natamycin / Q000494:pharmacology; D009761:Nystatin / Q000494:pharmacology*; D011201:Poultry Diseases / Q000188:drug therapy; D013170:Spores
D000143:Acids; D000935:Antifungal Agents; D003902:Detergents; D009761:Nystatin; D000666:Amphotericin B; D010866:Natamycin