Primary results of the radical operations for invasive carcinoma of the uterine cervix.
Sixty of the first 100 patients with cervical carcinoma admitted for treatment in 1962-1966 were found prior to the institution of final therapy to have an invasive tumour. The diagnosis was not confirmed in five cases until semiserial sections had been made from conisation preparations or preparations from the amputated portio of the uterus. In the other cases it was confirmed by biopsy. Thirty patients belonged clinically to Stage I, 17 to Stage II, eight to Stage III and five to Stage IV. Forty six (= 75 per cent) of the patients had a radical operation; 28 of them were in Stage I, 16 in Stage II, one in Stage III and one in Stage IV. The other patients were given either radiological therapy or just palliative therapy. Pelvic lymphonodectomy was always performed in connection with abdominal operations (17 Wertheim operations modo Ball, 25 modo Meigs, one modo TeLinde and one exenteration). Two patients had a vaginal operation. Eleven patients had carcinomatous metastases in the lymph nodes of the pelvic wall. The operative mortality was nil. The severest complications were: one ureteral lesion which was sustained and repaired during the operation, one uretero-vesico-vaginal fistula which was repaired four months later and two cases of pulmonary emboli. The follow-up period is only from one month to four years six months. Three of the patients on whom a radical operation was performed have died during this period and six have had a recurrence. As has been emphasised in recent literature, the primary results show that some patients with carcinoma of the cervix can be treated operatively. Experience of radical operations is indispensable, for especially certain radioincurable and recurrent cases should be treated operatively if possible.
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D008722:Methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011182:Postoperative Care; D011183:Postoperative Complications; D011300:Preoperative Care; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*