Studies on cholera carriers.
Cholera carrier studies in the Philippines in 1964-66 showed a prevalence rate of 21.7% among household contacts of cholera patients, and 8.4% in occupants of houses next door to one where a cholera patient lived, as opposed to 0.34% in the general population. The duration of the carrier state among 19 household carriers isolated for examination varied from 5 to 19 days. The vibrio concentration in the stool of contact carriers was 10(2)-15(5) per gram, as compared with 10(6)-19(9) per ml of rice-water stool in cholera cases.The agglutinin titre increased with time for carriers, as it does for patients. It declined to a very low level 8-12 weeks after recovery, with the exception of one proved long-term carrier.The strains isolated from carriers were identical in all respects, including virulence in infant rabbits, with strains isolated from patients-except that 3 carrier strains were rough.
D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010679:Philippines; D014733:Vibrio / Q000302:isolation & purification