Dihydrofolate reductase activity and loss of resistance in an antifolate-resistant subline of leukemia L1210 after discontinuation of treatment.
D000818:Animals; D002460:Cell Line / Q000187:drug effects / Q000201:enzymology; D004351:Drug Resistance; D007939:Leukemia L1210 / Q000201:enzymology*; D008297:Male; D008727:Methotrexate / Q000494:pharmacology; D051379:Mice; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis
D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate