L-asparaginase induced alteration of amethopterin (methotrexate) activity in mouse leukemia L5178Y.
D000818:Animals; D001215:Asparaginase / Q000494:pharmacology*; D001216:Asparagine / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003857:Deoxyuridine / Q000378:metabolism; D005260:Female; D007942:Leukemia, Experimental / Q000188:drug therapy / Q000378:metabolism*; D008727:Methotrexate / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000627:therapeutic use; D051379:Mice; D008815:Mice, Inbred Strains; D013997:Time Factors; D014316:Tritium
D004273:DNA, Neoplasm; D014316:Tritium; D001216:Asparagine; D001215:Asparaginase; D003857:Deoxyuridine; D008727:Methotrexate