RNA-dependent DNA polymerase: possible role in the amplification of ribosomal DNA in Xenopus oocytes.
2',5' - dimethyl - N(4')benzyl - N(4') - [desmethyl]rifampicin, a derivative of rifampicin, is used to acquire autoradiographic evidence that RNA-dependent DNA synthesis is involved in gene amplification during the early oogenesis of Xenopus laevis.
D000818:Animals; D001345:Autoradiography; D004247:DNA / Q000096:biosynthesis*; D004254:DNA Nucleotidyltransferases / Q000096:biosynthesis*; D005260:Female; D010053:Ovary / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D010063:Ovum / Q000187:drug effects / Q000378:metabolism; D012313:RNA / Q000502:physiology*; D012270:Ribosomes / Q000378:metabolism*; D012293:Rifampin / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium; D014981:Xenopus
D014316:Tritium; D012313:RNA; D004247:DNA; D004254:DNA Nucleotidyltransferases; D013936:Thymidine; D012293:Rifampin