Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
The solvolyses of phosphorocreatine (creatine phosphate) and models for phosphorocreatine have been investigated and the results are applied to the mechanism of action of creatine kinase (EC 2.7.3.2). A metaphosphate intermediate appears to be involved.
D003402:Creatine Kinase; D006146:Guanidines; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D009943:Organophosphorus Compounds; D010085:Oxidative Phosphorylation; D010725:Phosphocreatine; D013816:Thermodynamics
D006146:Guanidines; D009943:Organophosphorus Compounds; D010725:Phosphocreatine; D003402:Creatine Kinase