Formation of a piperidinium derivative from N-(5'-chloropentyl)-N-methylaminoaceto-2,6-xylidide in relation to the sustained local anaesthetic action on the sciatic nerve of the guinea-pig in vivo.
D000081:Acetamides; D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D002855:Chromatography, Thin Layer; D003500:Cyclization; D004058:Diffusion; D006168:Guinea Pigs; D010880:Piperidines / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D012584:Sciatic Nerve / Q000187:drug effects*; D014992:Xylenes
D000081:Acetamides; D000779:Anesthetics, Local; D010880:Piperidines; D000644:Quaternary Ammonium Compounds; D014992:Xylenes