Inhibition by pyrimidine analogues of the synthesis of folic acid by trachoma agents.
D000818:Animals; D002642:Chick Embryo; D002689:Chlamydia / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D046508:Culture Techniques; D004357:Drug Synergism; D005492:Folic Acid / Q000096:biosynthesis*; D002955:Leucovorin; D011739:Pyrimethamine / Q000494:pharmacology / Q000633:toxicity; D011743:Pyrimidines / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism
D011743:Pyrimidines; D013449:Sulfonamides; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D002955:Leucovorin; D011739:Pyrimethamine