Natural human antibodies to gram-negative bacteria: immunoglobulins G, A, and M.
Significant amounts of immunoglobulins G and M, and a small amount of natural antibodies reactive with Neisseria gonorrhoeae and Escherichia coli, have been detected in human adult serums by imnmunofluorescent techniques. Umbilical cord serums also contained substantial immunoglobulin-G antibody but little or no M or A. These findings challenge the concept that natural antibodies reactive with Gram-negative bacteria are primarily of the immunoglobulin-M class.
D000906:Antibodies; D001769:Blood; D002850:Chromatography, Gel; D004927:Escherichia coli Infections / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006069:Gonorrhea / Q000276:immunology*; D006801:Humans; D066298:In Vitro Techniques
D000906:Antibodies