Microbiological assay of vitamin B12 in the presence of tetracycline.
Treatment of a pharmaceutical preparation of vitamin B(12) and tetracycline with an ion-exchange resin by the batch method differentially adsorbed tetracycline, making possible a statistically reproducible microbiological assay of vitamin B(12) by the standard Escherichia coli plate method.
D001681:Biological Assay; D004926:Escherichia coli; D066298:In Vitro Techniques; D007475:Ion Exchange Resins; D013752:Tetracycline; D014805:Vitamin B 12
D007475:Ion Exchange Resins; D013752:Tetracycline; D014805:Vitamin B 12