Comparison of the radioisotope dilution-coated charcoal method and a microbiological method (L. leichmannii) for measuring vitamin B12 in serum.
A comparison has been made of the radioisotope dilution-coated charcoal method and a microbiological assay (with L. leichmannii as test organism) for determining the concentration of vitamin B(12) in serum. A satisfactory correlation was found between the results of the two methods. Under appropriate conditions the reproducibility of the radioisotope method compared favourably with that of the microbiological method.
D001681:Biological Assay; D002606:Charcoal; D003036:Cobalt Isotopes; D007778:Lactobacillus; D011865:Radioisotope Dilution Technique; D014805:Vitamin B 12 / Q000097:blood*
D003036:Cobalt Isotopes; D002606:Charcoal; D014805:Vitamin B 12