Wasting disease induced with cortisol acetate: studies in germ-free mice.
A marked difference in mortality was observed between germ-free mice and conventionally reared mice, both given a single injection of cortisol acetate. The incidence of death in germ-free mice was significantly lower than in conventionally reared mice. Mortality in germ-free mice treated with cortisol acetate was in creased by monocontamination with Escherichia coli.
D000818:Animals; D000831:Animals, Newborn; D002100:Cachexia / Q000209:etiology*; D004927:Escherichia coli Infections; D005856:Germ-Free Life; D006086:Graft vs Host Disease; D006854:Hydrocortisone / Q000633:toxicity*; D007422:Intestines; D051379:Mice; D009026:Mortality
D006854:Hydrocortisone