Lack of end-product inhibition and repression of leucine synthesis in a strain of Salmonella typhimurium.
Mutants of Salmonella have been isolated which luck either end product inhibition or repression of leucine biosynthesis. In a minimal saltsglucose medium, growth is not impaired by the lack of either control mechanism alone. The loss of both control mechanisms, however, leads to a 43 percent reduction in cell yield and a 1.5-fold reduction in the growth rate.
D003470:Culture Media; D004794:Enzyme Repression; D005947:Glucose / Q000378:metabolism; D007930:Leucine / Q000096:biosynthesis*; D008967:Molecular Biology; D009154:Mutation; D012486:Salmonella typhimurium / Q000378:metabolism*
D003470:Culture Media; D007930:Leucine; D005947:Glucose