[Role of bile acids and phospholipids in the stabilization of cholesterol in the gallbladder bile].
A removal of bile acids from the bile by gel-filtration results in a decrease of coagulation threefold of the cholesterol micelle. During enzymatic cleavage of phospholipids in the whole bile, cholesterol is retained in the solution. Under the same treatment of a fraction isolated from the dog bile employing filtration through Sephadex G-75 and devoid of bile acids, cholesterol completely precipitated. The data obtained indicate an important role of fatty acids in the stabilization of cholesterol in the bile, phospholipids play a less role in this process.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000502:physiology*; D002784:Cholesterol / Q000378:metabolism*; D004285:Dogs; D005704:Gallbladder / Q000378:metabolism*; D010743:Phospholipids / Q000502:physiology*
D001647:Bile Acids and Salts; D010743:Phospholipids; D002784:Cholesterol
O roli zhelchnykh kislot i fosfolipidov v stabilizatsii kholesterina v puzyrnoĭ zhelchi.