Homograft target cells: contact destruction in vitro by immune macrophages.
Specific adherence of immune macrophages to monolayers of target cells is a passive phenomenon which represents only the first step in the mutually destructive interaction of immune macrophages and target cells. A specific hemagglutinin, responsible for specific adherence, was eluted from well-washed immune macrophages by heat treatment. The nature of the events in the interaction subsequent to adherence are unknown, but apparently demand the biosynthetic activities of the immune macrophage.
D000906:Antibodies; D000937:Antigen-Antibody Reactions; D002701:Chloramphenicol / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D005347:Fibroblasts; D006386:Hemagglutination Tests; D007739:L Cells; D016031:Liver Transplantation; D008264:Macrophages; D013154:Spleen / Q000637:transplantation
D000906:Antibodies; D003609:Dactinomycin; D002701:Chloramphenicol