Topography and dynamics of synthesis of structural proteins of Newcastle disease virus.
Zhdanov, Victor M. (The D. I. Ivanovsky Institute of Virology, Moscow, USSR), Nonna B. Azadova, and Leonid V. Uryvayev. Topography and dynamics of synthesis of structural proteins of Newcastle disease virus. J. Bacteriol. 91:1902-1906. 1966.-Newcastle disease virus S and V antigens are synthesized in the cytoplasm, as revealed by the immunofluorescence method. In some experiments, S antigen was found also in the nucleoli. Actinomycin D moderately decreased the titer of infectious virus and V antigen and accelerated the time of appearance of mature virus. Proflavine sharply decreased the synthesis of both antigens and the release of mature virus.
D000941:Antigens / Q000096:biosynthesis*; D002466:Cell Nucleolus; D003593:Cytoplasm; D003609:Dactinomycin / Q000494:pharmacology; D005415:Flavins / Q000494:pharmacology; D005455:Fluorescent Antibody Technique; D066298:In Vitro Techniques; D009522:Newcastle disease virus / Q000378:metabolism*; D014764:Viral Proteins / Q000096:biosynthesis*
D000941:Antigens; D005415:Flavins; D014764:Viral Proteins; D003609:Dactinomycin