Study of the use of lincomycin aerosols in dogs.
This paper reports studies on different aspects of the administration of lincomycin by aerosol in dogs.The purpose of the study was to determine the depth of penetration of the drug into the lungs and its transfer into the blood, urine and tissues when administered as an aerosol.Special consideration was given to the possibility of side effects at the level of the bronchial mucosa, since this study was viewed as preliminary to the use of the antibiotic in humans.
D000336:Aerosols; D000818:Animals; D001431:Bacteriological Techniques; D001646:Bile / Q000032:analysis; D001980:Bronchi / Q000187:drug effects*; D004285:Dogs; D004342:Drug Hypersensitivity; D008034:Lincomycin / Q000008:administration & dosage* / Q000097:blood / Q000378:metabolism / Q000652:urine; D008099:Liver / Q000032:analysis; D008168:Lung / Q000032:analysis / Q000187:drug effects*
D000336:Aerosols; D008034:Lincomycin