Tolnaftate (tinactin), a new topical antifungal agent.
Using the double-blind technique, patients with tinea pedis, tinea cruris and tinea corporis were treated with either (a) 1% tolnaftate in a cream base or (b) the cream base.Twenty-four of 29 patients (82.7%) using 1% tolnaftate cream demonstrated clearing or great improvement of their lesions after three weeks of therapy, whereas only two of nine (22.2%) had similar results using the placebo.
D000935:Antifungal Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D009824:Ointments; D010919:Placebos; D014005:Tinea / Q000188:drug therapy*
D000935:Antifungal Agents; D009824:Ointments; D010919:Placebos