Failure of trasylol to reduce intestinal content of trypsin and chymotrypsin in man.
The daily output of trypsin and chymotrypsin was measured in the stools of four patients with an established ileostomy under controlled dietary and metabolic conditions for a control period of four days. Trasylol, given intravenously in a dose of 500,000 units over eight hours, failed to affect the output of enzymes over the next two days, or to alter the distribution of bound and soluble enzymes.
D007611:Aprotinin / Q000494:pharmacology* / Q000627:therapeutic use; D002918:Chymotrypsin / Q000032:analysis / Q000378:metabolism*; D003093:Colitis, Ulcerative / Q000201:enzymology; D005243:Feces / Q000032:analysis; D006801:Humans; D007081:Ileostomy; D007417:Intestinal Polyps / Q000201:enzymology; D014357:Trypsin / Q000032:analysis / Q000378:metabolism*
D007611:Aprotinin; D002918:Chymotrypsin; D014357:Trypsin