[Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate].
It is established that a decrease in glycogen content in liver begins at the early stages of intoxication with LG-63 and progresses with development of intoxication phenomena. Sugar content in liver and blood augments in parallel with decreasing content of glycogen in liver; concentration of ketone bodies and content of bisulfite-binding substances and pyruvic acid in liver also increase. In skeletal muscles, glycogen content was practically without changes; content of sugar, bisulfite-binding substances and pyruvic acid decreased while level of ketone bodies increased. In brain, utilization of ketone bodies decreased and in myocardium, increased.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D050260:Carbohydrate Metabolism; D002800:Cholinesterase Inhibitors / Q000506:poisoning*; D006003:Glycogen / Q000097:blood / Q000378:metabolism; D050356:Lipid Metabolism; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D009946:Organothiophosphorus Compounds / Q000506:poisoning*; D051381:Rats
D001786:Blood Glucose; D002800:Cholinesterase Inhibitors; D008112:Liver Glycogen; D009946:Organothiophosphorus Compounds; D006003:Glycogen
Obmen uglevodov pri otravlenii ingibitorom kholinésterazy O-étil-S-geksilmetiltiofosfonatom.