The effect of metrifonate on Brugia pahangi infections in domestic cats.
Metrifonate, an organophosphorus compound, caused a decline in the number of microfilariae in domestic cats experimentally infected with Brugia pahangi. It was found that the drug was active against both microfilariae and macrofilariae, but probably its greatest effect was on the macrofilarial stages. It is suggested that the drug should be used in filarial infections of man on a trial basis.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D002415:Cats; D005368:Filariasis / Q000188:drug therapy*; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D014236:Trichlorfon / Q000627:therapeutic use
D000871:Anthelmintics; D009943:Organophosphorus Compounds; D014236:Trichlorfon