Orientation of nonsense codons on the genetic map of the lac operon.
Intracodon recombination is used to orient the nonsense codons UGA, UAG, and UAA on the genetic map of the (lactose) lac operon of Escherichia coli. The 5'-end of these triplets is toward the operator end of the operon. A hypothesis is presented to explain the fact that the frequency of recombination between adjacent nucleotides is many times lower than expected.
D002874:Chromosome Mapping; D004926:Escherichia coli / Q000201:enzymology / Q000378:metabolism*; D005696:Galactosidases; D005815:Genetic Code; D007785:Lactose / Q000378:metabolism*; D008967:Molecular Biology; D009154:Mutation; D014364:Tryptophan / Q000378:metabolism
D014364:Tryptophan; D005696:Galactosidases; D007785:Lactose