N-demethylation of p-(N1-methylhydrazion methyl)-N-isopropyl benzamide (procarbazine), a cytostatically active methylhydrazine derivative, in the intact rat and in the isolated perfused rat liver.
D000818:Animals; D001565:Benzoates / Q000378:metabolism*; D002245:Carbon Dioxide / Q000032:analysis; D002247:Carbon Isotopes; D006834:Hydrazines / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D008745:Methylation; D008748:Methylcholanthrene / Q000494:pharmacology; D010084:Oxidation-Reduction; D010477:Perfusion / Q000295:instrumentation; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D051381:Rats
D001565:Benzoates; D002247:Carbon Isotopes; D006834:Hydrazines; D002245:Carbon Dioxide; D008748:Methylcholanthrene; D011335:Proadifen; D010634:Phenobarbital