Oxytocin: effects of degradation on radioimmunologic and biologic activity.
Incubation with thioglycollate destroyed biologic activity of oxytocin, but left immunologic activity intact. Incubation with plasma of pregnant women at term or with placental extract destroyed biologic and immunologic activities. Dissociation of biologic from immunologic sites is suggested.
D000818:Animals; D001669:Biochemical Phenomena; D001671:Biochemistry; D001681:Biological Assay; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D010121:Oxytocin / Q000502:physiology*; D010924:Placental Extracts; D010949:Plasma; D011247:Pregnancy; D011863:Radioimmunoassay; D051381:Rats; D013864:Thioglycolates
D010924:Placental Extracts; D013864:Thioglycolates; D010121:Oxytocin