Carbon tetrachloride metabolism in the rabbit.
1. Carbon tetrachloride was administered by stomach tube to rabbits and its distribution in fat, liver, kidney and muscle studied by gas liquid chromatography, during the next 48 hr.2. Chloroform, hexachloroethane and two unidentified chlorinated metabolites were detected in the tissues.3. Hexachloroethane may arise by dimerization of free trichloromethyl radicals.
D000273:Adipose Tissue / Q000032:analysis; D000818:Animals; D002251:Carbon Tetrachloride / Q000032:analysis / Q000378:metabolism*; D002725:Chloroform / Q000032:analysis; D002845:Chromatography; D006846:Hydrocarbons, Halogenated / Q000032:analysis / Q000096:biosynthesis; D007441:Intubation, Gastrointestinal; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D009132:Muscles / Q000032:analysis; D011817:Rabbits
D006846:Hydrocarbons, Halogenated; D002725:Chloroform; D002251:Carbon Tetrachloride