Elution of glomerular bound antibodies in experimental streptococcal glomerulonephritis.
lmmnunoglobulin G, eluted from glomeruli of rats with streptococcal glomerulonephritis, reacts with type 12 M protein of the streptococcus but not with other streptococcal or renal antigens. Thtrefore, this disease may be madiated by fixation of antigen-antibody complexes consisting of streptococcal M protein and type-specific antibody.
D000818:Animals; D000937:Antigen-Antibody Reactions; D002499:Centrifugation, Density Gradient; D004195:Disease Models, Animal; D005921:Glomerulonephritis / Q000276:immunology* / Q000382:microbiology / Q000628:therapy; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000302:isolation & purification*; D051381:Rats; D013290:Streptococcal Infections / Q000276:immunology*
D007074:Immunoglobulin G