Folate reductase and specific dihydrofolate reductase activities of the amethopterin-sensitive Streptococcus faecium var. durans.
Preliminary evidence is presented that indicates that the dihydrofolate reductase activity of amethopterin-sensitive Streptococcus faecium var. durans ATCC 8043 is separable into two dihydrofolate reductases, one of which also reduces folate.
D002850:Chromatography, Gel; D008727:Methotrexate / Q000494:pharmacology*; D013291:Streptococcus / Q000187:drug effects* / Q000201:enzymology*; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate