Spontaneous achlorhydria with atrophic gastritis in the Zollinger-Ellison syndrome.
This case report describes the occurrence of spontaneous, persistent achlorhydria in a patient with markedly raised basal acid secretion and diarrhoea for over two years (Zollinger-Ellison syndrome). Achlorhydria was due to the rapid development of severe atrophic gastritis in a gastric mucosa that had previously shown markedly increased numbers of parietal cells.
D000126:Achlorhydria / Q000150:complications*; D001285:Atropine / Q000494:pharmacology; D005753:Gastric Mucosa / Q000473:pathology; D005756:Gastritis / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013270:Stomach / Q000000981:diagnostic imaging / Q000187:drug effects / Q000503:physiopathology; D015043:Zollinger-Ellison Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology
D001285:Atropine