Oxidation of p-(N1-methylhydrazino methyl)-N-isopropyl benzamide (procarbazine) to the methylazo derivative and oxidative cleavage of the N2-C bond in the isolated perfused rat liver.
D000813:Anilides / Q000378:metabolism; D000818:Animals; D001391:Azo Compounds / Q000378:metabolism; D001565:Benzoates / Q000378:metabolism*; D002247:Carbon Isotopes; D006834:Hydrazines / Q000378:metabolism; D007097:Imines / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology; D010084:Oxidation-Reduction; D010477:Perfusion; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013053:Spectrophotometry
D000813:Anilides; D001391:Azo Compounds; D001565:Benzoates; D002247:Carbon Isotopes; D006834:Hydrazines; D007097:Imines; D008748:Methylcholanthrene; D011335:Proadifen