Membrane structure and function.
An understanding of the biochemical basis of membrane function is an important goal of present day biology. In this paper, a biochemical approach to the problem of the specific transport of sugars across the membrane of Escherichia coli is discussed. A new biochemical model for lactose transport system in this organism is presented, in which a specific membrane protein (M protein) plays the role of the sugar carrier. Experiments which have led to the discovery of such a protein, its specific labeling, and partial purification are briefly reviewed.
D002247:Carbon Isotopes; D002462:Cell Membrane / Q000502:physiology*; D004926:Escherichia coli / Q000378:metabolism*; D006027:Glycosides / Q000378:metabolism; D007785:Lactose / Q000378:metabolism; D008962:Models, Theoretical; D011506:Proteins / Q000502:physiology; D014316:Tritium
D002247:Carbon Isotopes; D006027:Glycosides; D011506:Proteins; D014316:Tritium; D007785:Lactose