Isolation of two plaque mutants of Western equine encephalitis virus differing in virulence for mice.
Two plaque mutants were isolated from tissue cultures infected persistently with Western equine encephalitis virus. A large plaque mutant proved to be markedly avirulent for mice.
D000818:Animals; D002460:Cell Line; D002642:Chick Embryo; D004668:Encephalitis Viruses / Q000276:immunology* / Q000472:pathogenicity*; D005347:Fibroblasts; D005827:Genetics, Microbial; D007110:Immunity, Active; D051379:Mice; D012509:Sarcoma; D014774:Virulence; D014776:Virus Cultivation