Reversible inhibition of ribosomal RNA synthesis in HeLa by lucanthone (Miracil D) with continued synthesis of DNA-like RNA.
D002455:Cell Division / Q000187:drug effects; D002499:Centrifugation, Density Gradient; D003593:Cytoplasm / Q000032:analysis; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D004586:Electrophoresis; D006367:HeLa Cells / Q000187:drug effects*; D008154:Lucanthone / Q000494:pharmacology*; D009363:Neoplasm Proteins / Q000096:biosynthesis; D010759:Phosphorus Isotopes; D012333:RNA, Messenger / Q000096:biosynthesis*; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D012270:Ribosomes / Q000378:metabolism*; D013997:Time Factors; D014316:Tritium
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D010759:Phosphorus Isotopes; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D014316:Tritium; D008154:Lucanthone