Demonstration of an alteration of ganglioside metabolism in Tay-Sachs disease.
D000293:Adolescent; D000328:Adult; D000818:Animals; D001706:Biopsy; D001921:Brain / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002675:Child, Preschool; D005696:Galactosidases; D005732:Gangliosides / Q000378:metabolism*; D006026:Glycoside Hydrolases / Q000378:metabolism; D006595:Hexosamines / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007223:Infant; D008064:Lipidoses / Q000201:enzymology / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008722:Methods; D008875:Middle Aged; D009132:Muscles / Q000201:enzymology* / Q000378:metabolism; D009135:Muscular Diseases / Q000378:metabolism; D009438:Neuraminic Acids / Q000378:metabolism; D009439:Neuraminidase; D051381:Rats; D014316:Tritium; D014733:Vibrio / Q000201:enzymology
D005732:Gangliosides; D006595:Hexosamines; D009438:Neuraminic Acids; D014316:Tritium; D005696:Galactosidases; D006026:Glycoside Hydrolases; D009439:Neuraminidase