Guanethidine and related agents. I. Mechanism of the selective blockade of adrenergic neurons and its antagonism by drugs.
D000578:Amidines / Q000378:metabolism; D000818:Animals; D000959:Antihypertensive Agents / Q000378:metabolism; D001949:Bretylium Compounds / Q000494:pharmacology; D003891:Desipramine / Q000494:pharmacology; D004336:Drug Antagonism; D004735:Energy Transfer; D006145:Guanethidine / Q000032:analysis / Q000378:metabolism; D006146:Guanidines / Q000378:metabolism*; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000378:metabolism; D007700:Kinetics; D008680:Metaraminol / Q000494:pharmacology; D009206:Myocardium / Q000032:analysis / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects*; D009638:Norepinephrine / Q000032:analysis / Q000378:metabolism; D011485:Protein Binding; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects*; D014316:Tritium; D014439:Tyramine / Q000494:pharmacology
D000578:Amidines; D000959:Antihypertensive Agents; D001949:Bretylium Compounds; D006146:Guanidines; D007546:Isoquinolines; D014316:Tritium; D008680:Metaraminol; D003891:Desipramine; D009638:Norepinephrine; D014439:Tyramine; D006145:Guanethidine