Trisporic acid synthesis in Blakeslea trispora.
Cultures of the (-) strain of Blakeslea trispora synthesize trisporic acid C, a sex hormone, from precursors made by cultures of the (+) strain. The precursors are nonacidic compounds isolated from the culture medium of the (+) strain by chloroform extraction. Actidione does not inhibit trisporic acid synthesis from isolated precursors, suggesting that the enzymes involved in the synthesis in cultures of the (-) strain are constitutive.
D002247:Carbon Isotopes; D002855:Chromatography, Thin Layer; D003470:Culture Media; D003509:Cyclohexanecarboxylic Acids / Q000032:analysis / Q000096:biosynthesis*; D003513:Cycloheximide / Q000494:pharmacology; D005658:Fungi / Q000378:metabolism*; D005827:Genetics, Microbial; D012739:Gonadal Steroid Hormones / Q000096:biosynthesis*; D007930:Leucine / Q000378:metabolism; D009154:Mutation; D013057:Spectrum Analysis; D014466:Ultraviolet Rays
D002247:Carbon Isotopes; D003470:Culture Media; D003509:Cyclohexanecarboxylic Acids; D012739:Gonadal Steroid Hormones; D003513:Cycloheximide; D007930:Leucine