Dentin matrix transformation: rapid induction of alkaline phosphatase and cartilage.
An acid-insoluble fraction of rat dentin rapidly initiates a chain reaction in mesenchyma after allogeneic transplantation to the subcutaneous tissues. The tooth matrix induced alkaline phosphatase activity within 24 hours; cartilage appeared within 5 days; bone and bone marrow formed within 14 days. The induced cartilage disappeared within 5 weeks, but bone persisted at least 1 year.
D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D002356:Cartilage / Q000166:cytology; D002471:Cell Transformation, Neoplastic; D003804:Dentin / Q000637:transplantation*; D003808:Dentin Solubility; D004790:Enzyme Induction; D010012:Osteogenesis; D051381:Rats; D014184:Transplantation, Homologous
D000469:Alkaline Phosphatase