Placental transfer of a substituted pteridine from fetus to mother.
In sito near-term sheep placentas transferred triamterene (2,4,7-triamino-6-phenyl-pteridine) from the fetus much more rapidly than to the fetus. This differential transfer effect may significantly influence the distribution of exogenous and endogenous compounds between the maternal and fetal compartments.
D000818:Animals; D005260:Female; D005470:Fluorometry; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011621:Pteridines / Q000378:metabolism*; D012756:Sheep; D014223:Triamterene / Q000097:blood / Q000378:metabolism*
D011621:Pteridines; D014223:Triamterene