[Increased hydroxylation of estrogens in humans after administration of drugs. Demonstration by HTO analysis of body water].
D000328:Adult; D000368:Aged; D001463:Barbiturates / Q000494:pharmacology / Q000627:therapeutic use; D001711:Biotransformation; D001826:Body Fluids / Q000032:analysis; D003520:Cyclophosphamide / Q000494:pharmacology; D004790:Enzyme Induction; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D006591:Hexobarbital / Q000494:pharmacology; D006801:Humans; D006878:Hydroxides / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000096:biosynthesis; D010634:Phenobarbital / Q000494:pharmacology; D013268:Stimulation, Chemical; D013412:Sulfadimethoxine / Q000494:pharmacology; D013874:Thiopental / Q000494:pharmacology; D014316:Tritium; D014867:Water / Q000032:analysis
D001463:Barbiturates; D006878:Hydroxides; D014867:Water; D014316:Tritium; D013412:Sulfadimethoxine; D004958:Estradiol; D003520:Cyclophosphamide; D006591:Hexobarbital; D006899:Mixed Function Oxygenases; D013874:Thiopental; D010634:Phenobarbital
Verstärkte Hydroxylierung von Ostrogenen beim Menschen nach Arzneimittelgabe Nachweis durch HTO-Analyse des Körperwassers.