Immunoassay of plasma low-density lipoproteins.
An immunoassay was developed for determining the concentration of the protein moiety of the low-density lipoproteins of human plasma. The concentration of this protein in the plasma was variable; it was higher than normal on the average in patients with familial hyperbetalipoproteinemia (type II) and endogenous hyperlipemia (type IV) and lower than normal in patients with fat-induced (type I) and mixed (type V) hyperlipemia. Patients with endogenous hyperlipemia were separable by the immunoassay into those with normal and those with supernormal low-density lipoprotein protein concentration.
D000328:Adult; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000235:genetics*; D007118:Immunoassay; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008722:Methods; D008875:Middle Aged; D013046:Specific Gravity
D008074:Lipoproteins; D002784:Cholesterol