Abnormal metabolism of secondary bile acids in patients with cirrhosis.
The composition of bile acids in human bile was determined in bile-rich duodenal fluid on four consecutive days in a group of seven patients with cirrhosis and eight control patients with no liver disease. There was a marked reduction of secondary biliary bile acids in cirrhotic patients. Possible mechanisms for these changes are discussed.
D001646:Bile / Q000032:analysis; D001647:Bile Acids and Salts / Q000032:analysis / Q000378:metabolism*; D002849:Chromatography, Gas; D004386:Duodenum / Q000032:analysis; D006801:Humans; D008103:Liver Cirrhosis / Q000378:metabolism*; D008111:Liver Function Tests
D001647:Bile Acids and Salts