Evidence for two molecular species of dihydrofolate reductase in amethopterin resistant and sensitive cells of the mouse leukemia L4946.
D000818:Animals; D000906:Antibodies; D002729:Chloromercuribenzoates / Q000494:pharmacology; D002850:Chromatography, Gel; D007942:Leukemia, Experimental / Q000201:enzymology* / Q000276:immunology; D007945:Leukemia, Lymphoid / Q000201:enzymology / Q000276:immunology; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D008970:Molecular Weight; D012965:Sodium Chloride / Q000494:pharmacology; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
D000906:Antibodies; D002729:Chloromercuribenzoates; D012965:Sodium Chloride; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate