Haemodynamic studies on newly diagnosed diabetics before and after adequate insulin treatment.
Haemodynamic observations were made during a short period of physical exercise on 10 male juvenile diabetics as soon as the diagnosis was made and again after adequate insulin treatment. It was found that the intra-arterial pressures rose to higher levels than in the control subjects at both examinations. The stroke volume increased and the heart rate decreased between the two examinations. These changes are tentatively attributed to metabolic adjustments after insulin therapy, offering more favourable conditions for the work of the heart muscle.
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D002302:Cardiac Output; D002306:Cardiac Volume; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology*; D005215:Fasting; D006321:Heart / Q000503:physiopathology; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D005082:Physical Exertion
D007328:Insulin