Chloramphenical: effect on DNA synthesis during phage development in Escherichia coli.
Chloramphenicol added at various times during intracellular development of various bacteriophages causes a reduction in the rate of synthesis of phage DNA. The reduction is faster the smaller the size of the DNA molecule in the mature phage.
D002701:Chloramphenicol / Q000494:pharmacology*; D003090:Coliphages / Q000187:drug effects*; D004261:DNA Replication / Q000187:drug effects*; D004279:DNA, Viral / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008970:Molecular Weight
D004279:DNA, Viral; D002701:Chloramphenicol