Regional lung function in patients with obstructive lung diseases.
Regional lung function was measured, using radioactive xenon-133, in a group of normal subjects and in three carefully defined groups of patients with obstructive lung disease. When compared with the normal subjects, patients in the emphysematous group showed a relative reduction of ventilation and perfusion to the upper zones, while patients having chronic bronchitis without cardiac or respiratory failure showed a predominantly lower zone defect. In the group of patients with chronic bronchitis with cardiac and respiratory failure no consistent pattern was found.
D000368:Aged; D001991:Bronchitis / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002245:Carbon Dioxide / Q000097:blood; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011660:Pulmonary Heart Disease / Q000150:complications; D011859:Radiography; D011868:Radioisotopes; D012129:Respiratory Function Tests; D013147:Spirometry; D014692:Ventilation-Perfusion Ratio; D014978:Xenon
D011868:Radioisotopes; D002245:Carbon Dioxide; D014978:Xenon; D010100:Oxygen