[The possible mechanism of the inhibitory effect of barbiturates on orotic acid biosynthesis in rat liver slices].
D000654:Amobarbital / Q000494:pharmacology; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D001463:Barbiturates / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002247:Carbon Isotopes; D003864:Depression, Chemical; D005182:Flavin-Adenine Dinucleotide / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D009963:Orotic Acid / Q000096:biosynthesis*; D010634:Phenobarbital / Q000494:pharmacology; D011743:Pyrimidines / Q000096:biosynthesis; D051381:Rats
D001463:Barbiturates; D002247:Carbon Isotopes; D011743:Pyrimidines; D005182:Flavin-Adenine Dinucleotide; D001224:Aspartic Acid; D009963:Orotic Acid; D000654:Amobarbital; D010634:Phenobarbital
Otnositel'no vozmozhnogo mekhanizma ingibiruiushchego deĭstviia barbituratov na biosintez orotovoĭ kisloty v srezakh pecheni krysy.