Effect of temperature on radiosensitivity of Newcastle disease virus.
Newcastle disease virus was irradiated at temperatures ranging from 2.2 to 60 C. An interaction between the thermal and ionizing energy was observed in the temperature region of 49 to 60 C. At 2.2 C, the hemagglutinin was considerably more radioresistant than the infectivity property. It is believed that radiation inactivation of Newcastle disease virus infectivity at low temperatures was due to nucleic acid degradation and at higher temperatures was due to protein denaturation.
D000906:Antibodies / Q000032:analysis; D001426:Bacterial Proteins; D009522:Newcastle disease virus / Q000276:immunology / Q000472:pathogenicity / Q000528:radiation effects*; D009691:Nucleic Acid Denaturation; D011489:Protein Denaturation; D011830:Radiation Effects; D013696:Temperature
D000906:Antibodies; D001426:Bacterial Proteins