L-glutamic acid decarboxylase: a new type in glial cells and human brain gliomas.
Human glial cells grown in culture and gliomas and white matter contain an l-glutamic acid decarboxylase which is stimulated markedly by carbonyl-trapping agents. In contrast, L-glutamic acid decarboxylase activity of human cerebral gray matter is strongly inhibited by carbonyl-trapping agents. These results suggest a glial localization of the new type of l-glutamic acid decarboxylase.
D000613:Aminobutyrates / Q000032:analysis; D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000201:enzymology*; D002262:Carboxy-Lyases / Q000032:analysis*; D046508:Culture Techniques; D005910:Glioma / Q000201:enzymology*; D005971:Glutamates; D006801:Humans; D009457:Neuroglia / Q000201:enzymology*
D000613:Aminobutyrates; D005971:Glutamates; D002262:Carboxy-Lyases