Demyelinating encephalomyelopathy associated with lead poisoning in nonhuman primates.
Lead poisoning was diagnosed in four primates by the finding of toxic amounts of lead in tissues. Abnormalities in the brain and spinal cord were characterized by vascular lesions and demyelination. These findings suggest a new animal model for the study of demyelination and strengthen the supposition that lead may be a factor in some idiopathic demyelinating diseases.
D000818:Animals; D001766:Blindness / Q000662:veterinary; D001921:Brain / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D003711:Demyelinating Diseases / Q000209:etiology* / Q000662:veterinary; D004195:Disease Models, Animal; D004827:Epilepsy / Q000662:veterinary; D005260:Female; D015186:Hominidae; D007855:Lead Poisoning / Q000150:complications* / Q000662:veterinary*; D008297:Male; D008992:Monkey Diseases / Q000473:pathology*