Cadmium toxicity decreased by dietary ascorbic acid supplements.
Feeding the environmental toxicant cadmium to young Japanese quail for 4 weeks produced growth retardation, severe anemia, low concentrations of iron in the liver, and high concentrations of cadmium in the liver. Dietary ascorbic acid supplements almost completely prevented the anemia and improved the growth rate but did not markedly alter concentrations of iron or cadmium in the liver.
D000740:Anemia / Q000139:chemically induced / Q000188:drug therapy; D000818:Animals; D001205:Ascorbic Acid / Q000627:therapeutic use*; D001717:Birds; D002104:Cadmium / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000633:toxicity*; D003300:Copper / Q000032:analysis; D004336:Drug Antagonism; D004781:Environmental Exposure; D005260:Female; D006130:Growth Disorders / Q000139:chemically induced / Q000188:drug therapy; D006400:Hematocrit; D007501:Iron / Q000032:analysis / Q000378:metabolism; D008099:Liver / Q000032:analysis / Q000378:metabolism; D008297:Male; D014131:Trace Elements / Q000032:analysis; D015032:Zinc / Q000032:analysis
D014131:Trace Elements; D002104:Cadmium; D003300:Copper; D007501:Iron; D015032:Zinc; D001205:Ascorbic Acid