Trimethoprim-sulphamethoxazole in acute osteomyelitis due to penicillin-resistant staphylococci in Uganda.
Most recent cases of staphylococcal osteomyelitis seen at Mulago Hospital, Kampala, have been due to penicillin-resistant organisms. Six severely ill patients-four with multiple bone lesions-were treated with trimethoprim-sulphamethoxazole; the response was prompt and satisfactory in all cases.
D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004357:Drug Synergism; D005260:Female; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000188:drug therapy*; D010403:Penicillin Resistance; D011743:Pyrimidines / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014454:Uganda
D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013420:Sulfamethoxazole