Hormone-sensitive adenyl cyclase: cytochemical localization in rat liver.
An electron microscopic procedure has been developed, using rat liver, for the localization of hormone-sensitive adenyl cyclase. Isoproterenol-sensitive adenyl cyclase is located almost exclusively in the parenchymal cells. In contrast, glucagon-sensitive adenyl cyclase is located primarily in the reticulo-endothelial cells but is also present in parenchymal cells. Sodium fluoride-sensitive adenyl cyclase is found in both cell types.
D000227:Adenine Nucleotides / Q000032:analysis*; D000262:Adenylyl Cyclases / Q000032:analysis; D000818:Animals; D004798:Enzymes / Q000032:analysis*; D005934:Glucagon / Q000494:pharmacology*; D006651:Histocytochemistry; D007545:Isoproterenol / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008854:Microscopy, Electron; D012157:Mononuclear Phagocyte System / Q000187:drug effects / Q000201:enzymology; D051381:Rats; D013268:Stimulation, Chemical
D000227:Adenine Nucleotides; D004798:Enzymes; D005934:Glucagon; D000262:Adenylyl Cyclases; D007545:Isoproterenol