Symptomatic hypercalcaemia in thyrotoxicosis.
In three patients with thyrotoxicosis and with symptomatic hypercalcaemia antithyroid therapy restored the plasma calcium concentration to normal, though initially in one case intravenous and oral neutral phosphate solution were required to curtail intractable vomiting.Nine cases have been recorded in which the plasma calcium concentration returned to normal after antithyroid treatment was started; all but one became normocalcaemic within eight weeks. It is suggested that in hypercalcaemic thyrotoxicosis a second pathological condition should be considered only if the plasma calcium concentration fails to return to normal within eight weeks.
D000328:Adult; D002118:Calcium / Q000097:blood; D002231:Carbimazole / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D006980:Hyperthyroidism / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010710:Phosphates / Q000008:administration & dosage; D013997:Time Factors; D014839:Vomiting / Q000188:drug therapy
D010710:Phosphates; D002231:Carbimazole; D002118:Calcium