Solution conformation of valinomycin-potassium ion complex.
The complete conformation of the valinomycin-potassium ion complex in methanol is presented. Extension from the reported secondary structure requires arguments and data relating to ester orientation, direction of coiling, side-chain orientation, and conformational stability. Conformation of the valinomycin-potassium ion complex provides a clear-cut example in which elucidation of conformation is sufficient to gain an understanding of molecular function which, in this case, is selective ion transport by a carrier mechanism.
D000900:Anti-Bacterial Agents; D002463:Cell Membrane Permeability; D046911:Macromolecular Substances; D000432:Methanol; D008956:Models, Chemical; D010455:Peptides; D011188:Potassium; D012996:Solutions; D013302:Streptomyces / Q000378:metabolism
D000900:Anti-Bacterial Agents; D046911:Macromolecular Substances; D010455:Peptides; D012996:Solutions; D011188:Potassium; D000432:Methanol