Antimycin A: stimulation of cell division and protein synthesis in Tetrahymena pyriformis.
Addition of antimycin A to a culture of Tetrahymena pyriformis caused an increase in cell division and protein synthesis in this ciliated protozoan. The antimycin effect is a function of the time of exposure to the antibiotic as well as of the age of the culture. A large accumulation of endoplasmic reticulum, reflecting increased protein synthesis, was visualized by electron microscopy in cells stimulated by the antimycin A.
D000968:Antimycin A / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects*; D004721:Endoplasmic Reticulum; D008854:Microscopy, Electron; D014176:Protein Biosynthesis; D013268:Stimulation, Chemical; D013768:Tetrahymena / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism*
D000968:Antimycin A