Oxychlordane, animal metabolite of chlordane: isolation and synthesis.
Oxychlordane (C(10)H(4)Cl(8)O), a minor heretofore unidentified metabolite, was isolated from fat of pigs on diets heavily dosed with pure isomers of the insecticide, chlordane (C(10)H(6)Cl(8)). Chemical and spectroscopic evidence provides bases for proposal of structure of the metabolite as 1-exo-2-endo-4,5,6,7,8,8-octachloro-2,3-exo-epoxy-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene.
D000273:Adipose Tissue / Q000032:analysis; D000818:Animals; D002706:Chlordan / Q000378:metabolism*; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D006846:Hydrocarbons, Halogenated / Q000032:analysis / Q000138:chemical synthesis* / Q000302:isolation & purification*; D007259:Infrared Rays; D009682:Magnetic Resonance Spectroscopy; D013057:Spectrum Analysis; D013237:Stereoisomerism; D013552:Swine
D006846:Hydrocarbons, Halogenated; D002706:Chlordan