Phenacetin nephropathy, with particular reference to the effect of surgery.
Sixteen patients suffering from phenacetin nephropathy were seen at one London hospital between June 1964 and January 1970. There were five deaths, three of them following a surgical operation. Phenacetin nephropathy occurs far more frequently than is generally considered. Unless patients are asked about the consumption of phenacetin routinely the diagnosis is usually missed. It is recommended that phenacetin and paracetamol should be available only on a doctor's prescription.
D000082:Acetaminophen / Q000009:adverse effects; D000328:Adult; D003404:Creatinine / Q000097:blood; D004739:England; D005260:Female; D006417:Hematuria / Q000139:chemically induced; D006801:Humans; D006977:Hypertension, Renal / Q000139:chemically induced; D007674:Kidney Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000139:chemically induced; D007677:Kidney Function Tests; D008131:London; D008297:Male; D008875:Middle Aged; D010615:Phenacetin / Q000008:administration & dosage / Q000009:adverse effects*; D011183:Postoperative Complications; D012606:Scotland; D014552:Urinary Tract Infections / Q000139:chemically induced; D014567:Urography; D014852:Wales
D000082:Acetaminophen; D003404:Creatinine; D010615:Phenacetin