Simple method of evaluating scrapie in mice.
Mice in advanced scrapie characteristically clasp their hindlegs together. As the disease progresses into the clasping stage, mice exhibit a sequence of identifiable hindleg reactions which have categorized and assigned relative scores permitting objective, quantitative evaluation of disease.
D000818:Animals; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D006614:Hindlimb / Q000503:physiopathology; D051379:Mice; D012608:Scrapie / Q000175:diagnosis* / Q000503:physiopathology; D012756:Sheep