Preclinical diabetes mellitus in precocious myocardial infarction.
A series of 45 patients who had a myocardial infarction before the age of 45 years has been studied and investigated for alterations of glucose tolerance, as shown by standard and prednisolone-primed glucose tolerance tests. Abnormal responses to standard glucose tolerance tests and prednisolone-primed glucose tolerance tests were obtained in 75.5 per cent of patients with myocardial infarction, compared with 8.8 per cent of controls.Sex, hypertension, obesity, and a positive family history did not affect the abnormalities of glucose tolerance. Various views concerning these abnormalities in glucose metabolism are discussed.
D000328:Adult; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000378:metabolism; D009765:Obesity; D012737:Sex Factors