Ribonuclease-inhibitor system abnormality in dystrophic mouse skeletal muscle.
Skeletal muscle extracts from mice with muscular dystrophy contain severalfold higher than normal levels of free alkaline ribonuclease II activity and none of the free ribonuclease inhibitor normally present. This abnormal pattern is not seen in heart or liver extracts from dystrophic mice.
D000818:Animals; D004195:Disease Models, Animal; D008099:Liver / Q000201:enzymology; D051379:Mice; D009132:Muscles / Q000201:enzymology; D009136:Muscular Dystrophies / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology; D012260:Ribonucleases / Q000032:analysis* / Q000037:antagonists & inhibitors; D014020:Tissue Extracts / Q000032:analysis
D014020:Tissue Extracts; D012260:Ribonucleases