Two forms of repair of DNA in mammalian cells following irradiation.
When Chinese hamster cells are lysed on top of an alkaline sucrose gradient, in time a fairly discrete DNA-containing molecular species is released from an apparently more complex material. Small doses of X-radiation speed the resolution of this complex while large doses degrade the material released from it. Incubation after irradiation reverses both effects.
D000818:Animals; D002460:Cell Line; D002499:Centrifugation, Density Gradient; D006224:Cricetinae; D046508:Culture Techniques; D004247:DNA / Q000378:metabolism / Q000528:radiation effects*; D006863:Hydrogen-Ion Concentration; D011830:Radiation Effects; D013395:Sucrose; D014316:Tritium
D014316:Tritium; D013395:Sucrose; D004247:DNA