Mutagenic action of N-methyl-N'-nitro-N-nitrosoguanidine on Gaffkya tibisci at alkaline pH.
Good yields of mutants were obtained by incubating cells of Gaffkya tibisci with N-methyl-N'-nitro-N-nitrosoguanidine in alkaline buffer. Nearly 50% of the survivors were auxotrophic mutants under the conditions described.
D005827:Genetics, Microbial; D006146:Guanidines / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008837:Micrococcus / Q000187:drug effects*; D009154:Mutation; D013289:Streptococcaceae / Q000187:drug effects*
D006146:Guanidines