Anticoagulation by ancrod for haemodialysis.
The defibrinating agent ancrod (Arvin) was used instead of heparin for intermittent haemodialysis. It was an effective, and apparently safe, anticoagulant and reduced the deposition of fibrin and leucocytes on the Cellophane membrane. Administration was more complicated and urea dialysance was less with ancrod than with heparin.
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D002476:Cellophane; D002908:Chronic Disease; D005337:Fibrin; D005340:Fibrinogen / Q000097:blood; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007962:Leukocytes; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D009393:Nephritis / Q000628:therapy; D007690:Polycystic Kidney Diseases / Q000628:therapy; D006435:Renal Dialysis; D014508:Urea; D014688:Venoms / Q000627:therapeutic use*
D000925:Anticoagulants; D008567:Membranes, Artificial; D014688:Venoms; D014508:Urea; D005337:Fibrin; D005340:Fibrinogen; D006493:Heparin; D002476:Cellophane