Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man.
Delta(9)-Tetrahydrocannabinol (the major active component of marihuana) administered intravenously to normal human volunteers persists in plasma for more than 3 days (t(1/2) = 56 hours). Its metabolites appear in plasma within 10 minutes after administration and persist along with the precursor compound. Delta(9)-Tetrahydrocannabinol is completely metabolized in man, and the radioactive metabolites are excreted in urine and feces for more than 8 days.
D000328:Adult; D002188:Cannabis / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002247:Carbon Isotopes; D002855:Chromatography, Thin Layer; D005243:Feces / Q000032:analysis; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008657:Metabolic Clearance Rate; D013997:Time Factors
D002247:Carbon Isotopes