Cell killing and the accumulation of breaks in the DNA of HEp-2 cells incubated in the presence of hydroxyurea.
D000963:Antimetabolites / Q000494:pharmacology; D002277:Carcinoma / Q000378:metabolism; D002460:Cell Line / Q000187:drug effects; D002499:Centrifugation, Density Gradient; D046508:Culture Techniques; D003513:Cycloheximide / Q000494:pharmacology; D004261:DNA Replication / Q000187:drug effects*; D004273:DNA, Neoplasm / Q000032:analysis / Q000096:biosynthesis*; D003864:Depression, Chemical; D006801:Humans; D006918:Hydroxyurea / Q000494:pharmacology*; D007822:Laryngeal Neoplasms / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D000963:Antimetabolites; D004273:DNA, Neoplasm; D014316:Tritium; D003513:Cycloheximide; D013936:Thymidine; D006918:Hydroxyurea