GABA and hippocampal inhibition.
Bicuculline, a specific GABA antagonist, diminishes basket cell inhibition of hippocampal pyramidal neurones, an inhibition which is not affected by strychnine.The inhibitory transmitter released by basket cells is thus probably GABA.
D000200:Action Potentials / Q000187:drug effects; D000409:Alanine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000613:Aminobutyrates / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D000818:Animals; D002415:Cats; D005998:Glycine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D006624:Hippocampus / Q000187:drug effects*; D007546:Isoquinolines / Q000494:pharmacology*; D013331:Strychnine / Q000494:pharmacology
D000613:Aminobutyrates; D007546:Isoquinolines; D013331:Strychnine; D000409:Alanine; D005998:Glycine