The metabolism of nicotine into two optically-active stereoisomers of nicotine-1'-oxide by animal tissues in vitro and by cigarette smokers.
D000818:Animals; D011232:Chemical Precipitation; D002840:Chromates / Q000494:pharmacology; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D006168:Guinea Pigs; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000378:metabolism; D008297:Male; D051379:Mice; D009538:Nicotine / Q000096:biosynthesis / Q000378:metabolism* / Q000652:urine; D010084:Oxidation-Reduction; D010087:Oxides / Q000096:biosynthesis / Q000378:metabolism / Q000652:urine; D011188:Potassium / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D011817:Rabbits; D012907:Smoking; D013045:Species Specificity; D013237:Stereoisomerism
D002840:Chromates; D010087:Oxides; D000644:Quaternary Ammonium Compounds; D009538:Nicotine; D011188:Potassium