Mixed leukocyte stimulation of normal peripheral leukocytes by autologous lymphoblastoid cells.
Lymphocyte culture lines can be established by using buffy coat cells from normal or diseased individuals. Established lymphocytoblasts from a normal donor were used in the one-way mixed leukocyte culture test and were found to stimulate the peripheral lymphocytes of that donor. These lymphocytoblasts were also capable of stimulating allogeneic lymphocyte populations.
D002460:Cell Line; D046508:Culture Techniques; D006648:Histocompatibility; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008937:Mitomycins / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014182:Transplantation, Autologous; D014316:Tritium
D008937:Mitomycins; D014316:Tritium; D013936:Thymidine