Monosodium glutamate-induced brain lesions: electron microscopic examination.
Albino mice injected with monosodium glutamate developed brain lesions in the arcuate nucleus of the hypothalamus. Lesions involved primarily microglial cells with no effect to the perikarya of neurons. Distal neuronal processes were only slightly affected.
D000818:Animals; D001927:Brain Diseases / Q000139:chemically induced*; D005503:Food Additives / Q000633:toxicity*; D005971:Glutamates / Q000633:toxicity*; D007031:Hypothalamus / Q000187:drug effects / Q000473:pathology*; D051379:Mice; D008854:Microscopy, Electron; D009336:Necrosis; D009457:Neuroglia / Q000473:pathology
D005503:Food Additives; D005971:Glutamates