title: Studies of the effect of metoclopramide and apomorphine on gastric emptying and secretion in man.
abstract: With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed the gastric emptying of test meals containing sodium citrate, and 10 mg of intravenous metoclopramide abolished the slowing of gastric emptying caused by apomorphine.
mesh_terms: D000577:Amides / Q000494:pharmacology*; D001058:Apomorphine / Q000494:pharmacology*; D001565:Benzoates / Q000494:pharmacology*; D002951:Citrates; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D005769:Gastrointestinal Motility / Q000187:drug effects; D005947:Glucose; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D012636:Secretory Rate / Q000187:drug effects; D013270:Stomach / Q000187:drug effects* / Q000502:physiology
chemical_list: D000577:Amides; D001565:Benzoates; D002951:Citrates; D005947:Glucose; D001058:Apomorphine