title: Peptic ulceration in Crohn's disease (reional enteritis).
abstract: The incidence of peptic ulceration in a personal series of 300 patients with Crohn's disease was 8%. Resection of 60 or more centimetres of the small intestine was associated with significantly increased acid output, both basally and following pentagastrin stimulation. Only five (4%) of the 124 patients who received steroid steroid therapy developed peptic ulceration. It is suggested that resection of the distal small bowel may be a factor in the probable increase of peptic ulceration in Crohn's disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005750:Gastric Juice / Q000378:metabolism; D006801:Humans; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000150:complications* / Q000209:etiology; D010455:Peptides; D012636:Secretory Rate; D013256:Steroids / Q000627:therapeutic use
chemical_list: D010455:Peptides; D013256:Steroids