Production of hypospadias in the rat by selective inhibition of fetal testicular 17 alpha-hydroxylase and C17-20-lyase.
D000014:Abnormalities, Drug-Induced; D000311:Adrenal Glands; D000312:Adrenal Hyperplasia, Congenital / Q000209:etiology*; D000818:Animals; D001835:Body Weight; D003864:Depression, Chemical; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000378:metabolism*; D007021:Hypospadias / Q000139:chemically induced*; D007192:Indenes; D007659:Ketones; D008190:Lyases / Q000037:antagonists & inhibitors*; D008297:Male; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D009281:Naphthalenes; D009929:Organ Size; D010088:Oxidoreductases / Q000378:metabolism; D011247:Pregnancy; D011374:Progesterone / Q000378:metabolism; D011725:Pyridines; D051381:Rats; D013737:Testis / Q000196:embryology / Q000201:enzymology* / Q000378:metabolism; D013739:Testosterone / Q000096:biosynthesis*
D007192:Indenes; D007659:Ketones; D009281:Naphthalenes; D011725:Pyridines; D013739:Testosterone; D011374:Progesterone; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D008190:Lyases