Antimicrobial properties of natural phenols and related compounds.
Obtusastyrene (4-cinnamylphenol) displays effective antimicrobial activity in vitro against a variety of gram-positive bacteria, yeasts, and molds. The activity of obtusastyrene is not appreciably affected by pH, and its minimal inhibitory concentrations, 12 to 25 mug/ml for bacteria and 12 to 100 mug/ml for fungi, compare favorably with those of a number of synthetic, phenolic antimicrobial agents.
D000362:Agar; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D055598:Chemical Phenomena; D002621:Chemistry; D005419:Flavonoids / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects* / Q000254:growth & development; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000138:chemical synthesis / Q000494:pharmacology*; D012997:Solvents
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005419:Flavonoids; D010636:Phenols; D012997:Solvents; D000362:Agar