title: Production of phenotypically epimeraseless yeast by L-arabinose.
abstract: The previous report from this laboratory that l-arabinose is a gratuitous inducer of the galactose transport system has been found to be an artefact resulting from the combination of galactose contamination of commercial samples of l-arabinose and inhibition by l-arabinose of galactose metabolism by inactivation of uridine-diphosphate-glucose-4-epimerase. As a result of l-arabinose inhibition of the metabolism of the contaminating galactose, galactose itself serves as a gratuitous inducer, producing phenotypically epimeraseless yeast.
mesh_terms: D001089:Arabinose / Q000494:pharmacology*; D002245:Carbon Dioxide / Q000096:biosynthesis; D002247:Carbon Isotopes; D002852:Chromatography, Ion Exchange; D003470:Culture Media; D004794:Enzyme Repression; D005285:Fermentation; D005374:Filtration; D005690:Galactose / Q000378:metabolism; D005827:Genetics, Microbial; D007535:Isomerases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010641:Phenotype; D012440:Saccharomyces / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D013053:Spectrophotometry; D013237:Stereoisomerism
chemical_list: D002247:Carbon Isotopes; D003470:Culture Media; D002245:Carbon Dioxide; D001089:Arabinose; D007535:Isomerases; D005690:Galactose