Effect of aspirin on renal clearance of 125I-diatrizoate.
Glomerular filtration rate was measured from the plasma disappearance curve after a single injection of sodium (125)I-diatrizoate. A therapeutic dose of aspirin in 13 subjects produced a mean fall in glomerular filtration rate of 10.5%.
D001241:Aspirin / Q000494:pharmacology*; D003973:Diatrizoate / Q000652:urine*; D005919:Glomerular Filtration Rate; D006801:Humans; D007456:Iodine Isotopes; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*
D007456:Iodine Isotopes; D003973:Diatrizoate; D001241:Aspirin