title: Mutation of Saccharomyces cerevisiae preventing uptake of S-adenosylmethionine.
abstract: A mutant has been isolated whose aberration severely restricts the ability of cells of Saccharomyces cerevisiae to take up S-adenosylmethionine. The mutation apparently also affects adenosylhomocysteine uptake, but not that of the S-adenosylmethionine moieties adenine, homocysteine, homoserine, or methionine, nor the sulfonium compound, S-methylmethionine. It is a single, chromosomal mutation whose expression is not dependent on the presence of ammonium ions.
mesh_terms: D000225:Adenine / Q000378:metabolism; D002247:Carbon Isotopes; D003124:Colorimetry; D003433:Crosses, Genetic; D003470:Culture Media; D003545:Cysteine / Q000378:metabolism; D005827:Genetics, Microbial; D006710:Homocysteine / Q000378:metabolism; D008715:Methionine / Q000378:metabolism*; D009154:Mutation; D009705:Nucleosides / Q000378:metabolism*; D012436:S-Adenosylmethionine / Q000378:metabolism; D012440:Saccharomyces / Q000254:growth & development / Q000378:metabolism*; D012694:Serine / Q000378:metabolism; D013912:Threonine / Q000378:metabolism
chemical_list: D002247:Carbon Isotopes; D003470:Culture Media; D009705:Nucleosides; D006710:Homocysteine; D013912:Threonine; D012694:Serine; D012436:S-Adenosylmethionine; D008715:Methionine; D000225:Adenine; D003545:Cysteine