Striated muscle fibers: facilitation of contraction at short lengths by caffeine.
One of the factors evidently responsible for decreasing the force of muscle contraction with shortening is inactivation of the myofibrils in the core of a muscle fiber. Caffeine antagonizes this inactivation and, correspondingly, changes the length-force relationship at short muscle lengths.
D000818:Animals; D001001:Anura; D001696:Biomechanical Phenomena; D002110:Caffeine / Q000494:pharmacology*; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009132:Muscles / Q000166:cytology; D009210:Myofibrils / Q000502:physiology; D013268:Stimulation, Chemical
D002110:Caffeine