Studies on the nature and managment of psoriasis.
Prevalence of psoriasis in Caucasians is estimated as 2 to 3 percent. Sound epidemiologic studies on a worldwide basis are needed to secure accurate prevalence rates for comparative purposes. Utilizing Stanford's psoriasis life histories records, the genetics of psoriasis has been explored by various means: statistical census data, pedigree analysis, and twin studies. This research suggests a multifactorial pattern of inheritance for psoriasis, implying that both genetic and environmental components are responsible for the manifestation of the disease. At present it is not possible to point to any single causative factor. Some of the suggested areas for research include study of uninvolved skin, growth control in the psoriatic lesion, viral causes, immunological aspects, and lipid metabolism.
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008055:Lipids / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000453:epidemiology / Q000209:etiology / Q000235:genetics / Q000628:therapy
D008055:Lipids