title: Imipramine metabolism: pH-dependent distribution and urinary excretion.
mesh_terms: D000328:Adult; D000643:Ammonium Chloride / Q000494:pharmacology; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D001933:Brain Stem / Q000378:metabolism; D002247:Carbon Isotopes; D002531:Cerebellum / Q000378:metabolism; D003891:Desipramine / Q000652:urine; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007099:Imipramine / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D007275:Injections, Intravenous; D007552:Isotonic Solutions; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000494:pharmacology; D012965:Sodium Chloride / Q000494:pharmacology
chemical_list: D001639:Bicarbonates; D002247:Carbon Isotopes; D007552:Isotonic Solutions; D000643:Ammonium Chloride; D012965:Sodium Chloride; D012964:Sodium; D007099:Imipramine; D003891:Desipramine