Control of pyrimidine biosynthesis in human lymphocytes. Induction of glutamine-utilizing carbamyl phosphate synthetase and operation of orotic acid pathway during blastogenesis.
D000328:Adult; D000812:Anhydrides; D002219:Carbamates; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D002454:Cell Differentiation; D002460:Cell Line / Q000187:drug effects; D011232:Chemical Precipitation; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D002956:Citrulline / Q000378:metabolism; D046508:Culture Techniques; D003609:Dactinomycin / Q000494:pharmacology; D004586:Electrophoresis; D004790:Enzyme Induction; D005971:Glutamates; D005973:Glutamine / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D037102:Lectins / Q000494:pharmacology; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology*; D009963:Orotic Acid / Q000378:metabolism*; D010209:Paper; D010756:Phosphoric Acids; D010770:Phosphotransferases / Q000096:biosynthesis / Q000097:blood* / Q000302:isolation & purification; D011691:Puromycin / Q000494:pharmacology; D011743:Pyrimidines / Q000096:biosynthesis*; D000644:Quaternary Ammonium Compounds; D013431:Sulfates; D014498:Uracil / Q000096:biosynthesis* / Q000378:metabolism; D014500:Uracil Nucleotides / Q000096:biosynthesis / Q000302:isolation & purification
D000812:Anhydrides; D002219:Carbamates; D002247:Carbon Isotopes; D005971:Glutamates; D037102:Lectins; D010756:Phosphoric Acids; D011743:Pyrimidines; D000644:Quaternary Ammonium Compounds; D013431:Sulfates; D014500:Uracil Nucleotides; D005973:Glutamine; D002245:Carbon Dioxide; D003609:Dactinomycin; D002956:Citrulline; D011691:Puromycin; D014498:Uracil; D009963:Orotic Acid; D010770:Phosphotransferases