Correlation of biological to chromatographic data for two mycotoxins elaborated by Fusarium.
Thirty-seven identified strains of Fusarium, most of them isolated from fescue grass, were tested for their ability to elaborate mycotoxins in laboratory culture. The presence of the toxins was determined by infrared light, thin-layer chromatography, mouse toxicity, fungistatic effects, and phytotoxic properties. A good correlation was demonstrated between T-2 toxin detection by thin-layer chromatography and inhibition of Rhodotorula rubra by culture extracts. All of the strains producing either butenolide or T-2 toxin were toxic to mice with but one exception; those producing T-2 toxin inhibited growth of the yeast.
D000818:Animals; D002474:Cell-Free System; D002855:Chromatography, Thin Layer; D003470:Culture Media; D005670:Fusarium / Q000032:analysis / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D007259:Infrared Rays; D051379:Mice; D009183:Mycotoxins / Q000032:analysis / Q000096:biosynthesis* / Q000633:toxicity; D063245:Plant Development; D010944:Plants / Q000187:drug effects; D006109:Poaceae; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D013045:Species Specificity; D003313:Zea mays
D003470:Culture Media; D009183:Mycotoxins