Effects of guanidine derivatives on mitochondrial function. 3. The mechanism of phenethylbiguanide accumulation and its relationship to in vitro respiratory inhibition.
D000418:Albumins / Q000494:pharmacology; D000818:Animals; D000968:Antimycin A / Q000494:pharmacology; D001645:Biguanides / Q000378:metabolism* / Q000494:pharmacology; D001665:Binding Sites; D001692:Biological Transport; D002247:Carbon Isotopes; D003911:Dextrans; D004140:Dinitrophenols / Q000494:pharmacology; D004579:Electron Transport / Q000187:drug effects; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D008293:Malates / Q000378:metabolism; D008564:Membrane Potentials; D008931:Mitochondria, Muscle / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D008933:Mitochondrial Swelling; D009206:Myocardium / Q000166:cytology / Q000378:metabolism; D009840:Oligomycins / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects*; D010113:Oxyphenbutazone / Q000494:pharmacology; D010627:Phenethylamines / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology; D011773:Pyruvates / Q000378:metabolism; D012402:Rotenone / Q000494:pharmacology; D012964:Sodium / Q000494:pharmacology; D013229:Stearic Acids / Q000494:pharmacology; D013395:Sucrose; D014316:Tritium; D014475:Uncoupling Agents / Q000494:pharmacology; D014634:Valinomycin / Q000494:pharmacology
D000418:Albumins; D001645:Biguanides; D002247:Carbon Isotopes; D003911:Dextrans; D004140:Dinitrophenols; D008293:Malates; D009840:Oligomycins; D010627:Phenethylamines; D011773:Pyruvates; D013229:Stearic Acids; D014475:Uncoupling Agents; D012402:Rotenone; D014316:Tritium; D014634:Valinomycin; D013395:Sucrose; D000968:Antimycin A; D012964:Sodium; D010113:Oxyphenbutazone; D008274:Magnesium; D011188:Potassium