Testosterone therapy for anaemia in maintenance dialysis.
Intramuscular testosterone 250-500 mg weekly given to 25 patients on long-term haemodialysis produced a significant rise in haemoglobin level in all patients. The response was reversible when the drug was stopped. Treatment was effective in bilaterally nephrectomized patients and those with intact kidney tissue. The use of intramuscular testosterone is recommended for all adult patients on long-term haemodialysis in order to eliminate the need for routine blood transfusions.
D000328:Adult; D000740:Anemia / Q000517:prevention & control*; D001803:Blood Transfusion; D005260:Female; D005921:Glomerulonephritis; D006400:Hematocrit; D006452:Hemoglobinometry; D006628:Hirsutism / Q000139:chemically induced; D006801:Humans; D007273:Injections, Intramuscular; D007501:Iron / Q000097:blood; D008297:Male; D008875:Middle Aged; D011317:Priapism / Q000139:chemically induced; D011704:Pyelonephritis; D006435:Renal Dialysis / Q000009:adverse effects*; D013739:Testosterone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D013739:Testosterone; D007501:Iron