Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. I. Determination of substrate specificity by the cytochrome P-450 and P-448 fractions.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism*; D003580:Cytochromes / Q000378:metabolism*; D003640:Dealkylation; D066298:In Vitro Techniques; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010627:Phenethylamines / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats
D001580:Benzopyrenes; D003580:Cytochromes; D010627:Phenethylamines; D008748:Methylcholanthrene; D006899:Mixed Function Oxygenases; D010634:Phenobarbital