Actinomycin D and hepatic polyribosomal disaggregation. Evidence for different half-lives of mRNA of free and membrane-boudn polyribosomes.
D000818:Animals; D002247:Carbon Isotopes; D002499:Centrifugation, Density Gradient; D003609:Dactinomycin / Q000494:pharmacology*; D003864:Depression, Chemical; D005260:Female; D006207:Half-Life; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D008854:Microscopy, Electron; D009963:Orotic Acid / Q000378:metabolism; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism*; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism*
D002247:Carbon Isotopes; D012333:RNA, Messenger; D003609:Dactinomycin; D009963:Orotic Acid; D007930:Leucine