title: Requirement of protein synthesis for bacteriophage phi X174 superinfection exclusion.
abstract: Within 5 to 10 min at 37 C, bacteria infected by bacteriophage phiX174 acquire the ability to exclude superinfecting phiX particles from reproducing themselves. The superinfecting phage are blocked at a stage prior to synthesis of the parental replicative form molecule; the superinfecting deoxyribonucleic acid remains as intact (infective) single strands. Establishment of superinfection exclusion and its maintenance require protein synthesis.
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D001435:Bacteriophages / Q000254:growth & development* / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D002586:Cesium; D002701:Chloramphenicol / Q000494:pharmacology; D002712:Chlorides; D004261:DNA Replication; D004279:DNA, Viral / Q000032:analysis / Q000096:biosynthesis; D005796:Genes; D005827:Genetics, Microbial; D009154:Mutation; D010759:Phosphorus Isotopes; D014762:Viral Interference; D014764:Viral Proteins / Q000096:biosynthesis; D014779:Virus Replication
chemical_list: D001426:Bacterial Proteins; D002712:Chlorides; D004279:DNA, Viral; D010759:Phosphorus Isotopes; D014764:Viral Proteins; D002586:Cesium; D002701:Chloramphenicol