title: Spontaneous and persisting decrease in maximal acid output.
abstract: A spontaneous decrease in maximal acid output was observed in three control subjects and in seven patients with duodenal ulcer. The decreased output was due to a decrease in volume and to a lower concentration in six subjects and to a decrease in volume in four subjects. In some cases the decrease in output occurred within a period of weeks. Patients with a pronounced decrease remained asymptomatic for a prolonged period.
mesh_terms: D000293:Adolescent; D000328:Adult; D004381:Duodenal Ulcer / Q000503:physiopathology*; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000494:pharmacology; D011720:Pyrazoles; D012636:Secretory Rate; D013270:Stomach / Q000187:drug effects
chemical_list: D010455:Peptides; D011720:Pyrazoles; D006632:Histamine