Thyrocalcitonin: stimulation of secretion by pentagastrin.
Administration of a small dose of pentagastrin, a synthetic pentapeptide containing the biologically active portion of the native hormone gastrin, results in a marked, rapid, transitory increase in thyrocalcitonin secretion in the pig. Gastrin or a related gastrointestinal peptide may be important in the physiological secretion of thyrocalcitonin, such as that which occurs when calcium salts are introduced into the gastrointestinal tract.
D000818:Animals; D002116:Calcitonin / Q000097:blood / Q000378:metabolism*; D002118:Calcium / Q000494:pharmacology; D005755:Gastrins / Q000494:pharmacology*; D010455:Peptides / Q000494:pharmacology*; D013386:Succinates / Q000494:pharmacology; D013552:Swine; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism; D013965:Thyroidectomy; D013997:Time Factors
D005755:Gastrins; D010455:Peptides; D013386:Succinates; D002116:Calcitonin; D002118:Calcium