title: Platelet aggregation and strenuous exercise.
abstract: 1. Platelet aggregation in the Chandler's tube has been found to be increased in a group of normal male and female volunteers who undertook strenuous physical exercise. This coincided with acceleration of the ;intrinsic' blood clotting system and a rise in fibrinogen. The rise in fibrinogen occurred despite increased fibrinolysis.2. The study confirms the sensitivity of the platelet aggregation system to changes in the ;intrinsic' clotting mechanism. Acceleration of this system in this study resulted from a physiological cause and produced accelerated aggregation in the coagulation-affected phase.
mesh_terms: D000328:Adult; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D005340:Fibrinogen; D005342:Fibrinolysis; D006400:Hematocrit; D006452:Hemoglobinometry; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D005082:Physical Exertion; D010973:Platelet Adhesiveness; D013916:Thrombelastography; D013997:Time Factors
chemical_list: D005340:Fibrinogen