An enzymatic basis for variation in response to allopurinol. Hypoxanthine-guanine phosphoribosyltransferase deficiency.
D000225:Adenine / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000368:Aged; D000493:Allopurinol / Q000494:pharmacology*; D002648:Child; D003404:Creatinine / Q000652:urine; D005964:Glucosyltransferases / Q000378:metabolism*; D006073:Gout / Q000235:genetics / Q000652:urine*; D006147:Guanine / Q000378:metabolism; D006801:Humans; D007042:Hypoxanthines / Q000378:metabolism / Q000652:urine; D008297:Male; D008661:Metabolism, Inborn Errors / Q000652:urine*; D008875:Middle Aged; D011687:Purines / Q000096:biosynthesis* / Q000652:urine; D014527:Uric Acid / Q000652:urine; D014970:Xanthines / Q000652:urine
D007042:Hypoxanthines; D011687:Purines; D014970:Xanthines; D014527:Uric Acid; D006147:Guanine; D000493:Allopurinol; D003404:Creatinine; D005964:Glucosyltransferases; D000225:Adenine