Messenger RNA patterns in rat liver nuclei before and after treat-ment with growth hormone.
Like cortisol, growth hormone enhances RNA synthesis in rat liver nuclei. However, DNA-RNA hybridization experiments show that the application of growth hormone does not stimulate the formation of new species of messenger RNA. The latter phenomenon was observed after treatment with cortisol.
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism*; D004247:DNA; D013006:Growth Hormone / Q000494:pharmacology*; D006824:Hybridization, Genetic; D006854:Hydrocortisone / Q000494:pharmacology*; D007016:Hypophysectomy; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009963:Orotic Acid / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D010759:Phosphorus Isotopes; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D013268:Stimulation, Chemical; D014316:Tritium
D010710:Phosphates; D010759:Phosphorus Isotopes; D014316:Tritium; D009963:Orotic Acid; D012313:RNA; D013006:Growth Hormone; D004247:DNA; D006854:Hydrocortisone