Cholinesterase in plasma: first reported absence in the Bantu; half-life determination.
A Bantu schoolgirl is the first non-Caucasoid found homozygous for the "silent" cholinesterase gene. Investigation of her family revealed two heterozygotes. The propositus possesses no antibody to normal cholinesterase. Transfused cholinesterase had in her a half-life of approximately 10 days.
D000293:Adolescent; D044383:Black People; D002802:Cholinesterases / Q000097:blood*; D003992:Dibucaine; D005260:Female; D005459:Fluorides; D005809:Genes, Regulator; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008661:Metabolism, Inborn Errors; D013390:Succinylcholine
D002802:Cholinesterases; D013390:Succinylcholine; D003992:Dibucaine; D005459:Fluorides