Intercellular communication and tissue growth. 3. Thyroid cancer.
Intercellular communication was examined in normal and cancerous isolated thyroids with an intracellular electrical technique. The cells of normal thyroid (rat, mouse, hamster, man) communicate, within any given follicle, through permeable junctions. The cells of a wide variety of thyroid cancers (rat, hamster) do not communicate to any detectable degree and have resting membrane potentials lower than those of normal cells.
D000818:Animals; D006224:Cricetinae; D006801:Humans; D008564:Membrane Potentials; D051379:Mice; D051381:Rats; D013964:Thyroid Neoplasms