Potential folic acid antagonists. 3. The antitumor and folate reductase inhibitory properties of some irreversibly acting 6-N-substituted 2,4,6-triamino-5-(4-carbethoxyphenylazo)pyrimidines.
D000818:Animals; D001391:Azo Compounds / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D001665:Binding Sites; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy / Q000201:enzymology; D005260:Female; D005493:Folic Acid Antagonists; D007413:Intestinal Mucosa / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008297:Male; D051379:Mice; D011743:Pyrimidines / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity
D001391:Azo Compounds; D005493:Folic Acid Antagonists; D011743:Pyrimidines