Photodimer of thymine in ultraviolet-irradiated DNA: proof of structure by x-ray diffraction.
Dimethylthymine was photodimerized with ultraviolet radiation, and the structure of one of the resulting dimers, the cis 5,5 : 6,6 isomer, was determined by single-crystal x-ray diffraction. This isomer is the same as that obtained by ultraviolet irradiation of DNA; hence the structure of the thymine dimer in irradiated DNA is now proved.
D004247:DNA / Q000528:radiation effects*; D011108:Polymers; D011830:Radiation Effects; D011854:Radiochemistry; D013237:Stereoisomerism; D013941:Thymine; D014466:Ultraviolet Rays; D014961:X-Ray Diffraction
D011108:Polymers; D004247:DNA; D013941:Thymine