Cytodifferentiation during insect metamorphosis: the galea of silkmoths.
In the galea of silkmoths undergoing metamorphosis, generalized epidermal cells, which had previousty secreted pupal cuticle, transform into highly specialized cells producing a new protein, the enzyme cocoonase. These cells first segregate by mitosis and displacement, then grow rapidly through endomitosis and accumulation of RNA-rich cytoplasm, and finally begin rapid synthesis of cocoonase. Replication of DNA continues in fully differentiated cells synthesizing cocoonase.
D000818:Animals; D001345:Autoradiography; D012831:Bombyx / Q000254:growth & development* / Q000378:metabolism; D002454:Cell Differentiation; D004261:DNA Replication; D005088:Exocrine Glands / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D008239:Lysine / Q000378:metabolism; D008675:Metamorphosis, Biological; D008938:Mitosis; D010447:Peptide Hydrolases / Q000096:biosynthesis; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D012313:RNA; D010447:Peptide Hydrolases; D007930:Leucine; D008239:Lysine; D013936:Thymidine