Occurrence of 7-methylguanine in nucleic acids of rat liver.
1. Microsomal and soluble RNA of rat liver have been studied by column and paper chromatography after administration of [Me-(14)C]methionine; evidence was obtained for the occurrence of 7-methylguanine, the methyl group being derived from methionine. 2. No evidence was obtained for the occurrence of 7-methylguanine in DNA.
D000818:Animals; D002247:Carbon Isotopes; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D004247:DNA / Q000378:metabolism*; D005260:Female; D006147:Guanine / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008715:Methionine / Q000378:metabolism*; D008745:Methylation; D008861:Microsomes / Q000378:metabolism; D012313:RNA / Q000378:metabolism*; D012343:RNA, Transfer / Q000378:metabolism*; D051381:Rats; D014316:Tritium
D002247:Carbon Isotopes; D014316:Tritium; D006147:Guanine; D012313:RNA; D004247:DNA; D012343:RNA, Transfer; D008715:Methionine