Aspirin: action on receptor in the tooth.
Impulse frequency recorded from dentinal receptors in the cat's tooth provided an indication of sensory excitation. Topical application of aspirin to the dentin promptly inhibited both steady-state discharge and response to a brief heat stimulus. When the drug was washed out, the initial excitability was restored in 15 minutes.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D002415:Cats; D003804:Dentin / Q000187:drug effects / Q000294:innervation*; D003864:Depression, Chemical; D005071:Evoked Potentials / Q000187:drug effects; D006358:Hot Temperature; D010146:Pain / Q000188:drug therapy; D011984:Sensory Receptor Cells / Q000187:drug effects / Q000502:physiology*
D001241:Aspirin