LSD in mice: abnormalities in meiotic chromosomes.
Meiotic chromosomes of six mice injected with high doses of lysergic acid diethylamide (LSD-25) and of six controls were studied. Several breaks, gaps, and unidentifiable fragments were found in the treated but, with a few exceptions, not in the control animals. Secondary constrictions were more numerous in the treated than in the untreated mice. Possible consequences are discussed.
D000818:Animals; D002869:Chromosome Aberrations / Q000139:chemically induced; D025063:Chromosome Disorders; D002875:Chromosomes / Q000187:drug effects*; D008238:Lysergic Acid Diethylamide; D008297:Male; D008540:Meiosis; D051379:Mice
D008238:Lysergic Acid Diethylamide