Anthramycin, a new type of DNA-inhibiting antibiotic: reaction with DNA and effect on nucleic acid synthesis in mouse leukemia cells.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D002247:Carbon Isotopes; D002417:Cattle; D002499:Centrifugation, Density Gradient; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D046508:Culture Techniques; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003609:Dactinomycin / Q000494:pharmacology; D003864:Depression, Chemical; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007942:Leukemia, Experimental / Q000378:metabolism*; D051379:Mice; D009691:Nucleic Acid Denaturation; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D013053:Spectrophotometry; D013936:Thymidine / Q000378:metabolism; D013950:Thymus Gland; D014316:Tritium
D000903:Antibiotics, Antineoplastic; D002247:Carbon Isotopes; D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D014316:Tritium; D003609:Dactinomycin; D013936:Thymidine