Prebiotic synthesis: phosphorylation in aqueous solution.
Formation of uridine-5'-phosphate from uridine and inorganic phosphate in aqueous solution is effected by the following condensing agents: cyanogen, cyanoformamide, cyanate, cyanamide, thioformate, ethylisocyanide, and a watersoluble carbodiimide. The yields are always small, even when a large excess of condensing agent is used. The cyclization of uridine-3'-(2')-phosphate occurs under the same conditions but in much greater yield.
D000577:Amides; D005075:Biological Evolution; D002854:Chromatography, Paper; D003485:Cyanates; D003486:Cyanides; D005561:Formates; D007094:Imides; D000069497:Origin of Life; D010710:Phosphates; D012996:Solutions; D013053:Spectrophotometry; D014500:Uracil Nucleotides / Q000138:chemical synthesis*; D014508:Urea; D014529:Uridine
D000577:Amides; D003485:Cyanates; D003486:Cyanides; D005561:Formates; D007094:Imides; D010710:Phosphates; D012996:Solutions; D014500:Uracil Nucleotides; D014508:Urea; D014529:Uridine