Mechanism of alpha-glycerophosphate regulation of acetyl-coenzyme A carboxylase of Saccharomyces cerevisiae.
The mechanism proposed for the activation of animal acetyl-coenzyme A (CoA) carboxylase by alpha-glycerophosphate, namely, the removal of inhibitory palmityl-CoA via glyceride synthesis, is not the only possible one in the yeast system because extracts exhibiting marked stimulation of acetyl-CoA carboxylase activity by alpha-glyerophosphate show a lack of acyl-CoA compounds.
D002951:Citrates / Q000378:metabolism; D003065:Coenzyme A / Q000378:metabolism; D005989:Glycerides / Q000096:biosynthesis; D005994:Glycerophosphates / Q000378:metabolism*; D008025:Ligases / Q000378:metabolism*; D008967:Molecular Biology; D012440:Saccharomyces / Q000201:enzymology* / Q000378:metabolism
D002951:Citrates; D005989:Glycerides; D005994:Glycerophosphates; D008025:Ligases; D003065:Coenzyme A