Inhibition by actinomycin D of DNA and RNA synthesis and of skin carcinogenesis initiated by 7,12-dimethylbenz[a]anthracene or beta-propiolactone.
D000818:Animals; D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D002273:Carcinogens / Q000494:pharmacology*; D002277:Carcinoma / Q000188:drug therapy; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003609:Dactinomycin / Q000627:therapeutic use*; D005260:Female; D007274:Injections, Intraperitoneal; D007783:Lactones / Q000494:pharmacology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D010212:Papilloma / Q000188:drug therapy; D012334:RNA, Neoplasm / Q000096:biosynthesis; D012878:Skin Neoplasms / Q000188:drug therapy; D013936:Thymidine; D014316:Tritium
D001551:Benz(a)Anthracenes; D002273:Carcinogens; D004273:DNA, Neoplasm; D007783:Lactones; D012334:RNA, Neoplasm; D014316:Tritium; D003609:Dactinomycin; D013936:Thymidine