Biochemical mechanism of drug resistance. VII. Inhibition of orotic acid metabolism by 5-azacytidine in leukemic mice sensitive and resistant to 5-azacytidine.
D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology*; D002247:Carbon Isotopes; D002474:Cell-Free System; D003864:Depression, Chemical; D005260:Female; D007942:Leukemia, Experimental / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D009705:Nucleosides / Q000494:pharmacology*; D009963:Orotic Acid / Q000378:metabolism* / Q000652:urine; D010710:Phosphates / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis
D000963:Antimetabolites; D002247:Carbon Isotopes; D009705:Nucleosides; D010710:Phosphates; D009963:Orotic Acid; D012313:RNA