Circadian rhythm of plasma 11-hydroxycorticosteroids in psychiatric disorders.
Studies of the circadian rhythm in plasma 11-O.H.C.S. levels showed that a subgroup of affective psychotics had higher plasma 11-OHCS values as compared with schizophrenic and other psychotic subgroups, and a somewhat less regular rhythm. One patient with depression who was studied over 48-hour periods showed a reduction in plasma 11-OHCS levels with clinical recovery. An accentuated fall and rise in plasma 11-OHCS values in the night and early morning samples, respectively, was observed in the schizophrenic subgroup.
D000425:Alcohol Amnestic Disorder / Q000097:blood; D001714:Bipolar Disorder / Q000097:blood; D002940:Circadian Rhythm; D003345:Corticosterone / Q000097:blood; D003704:Dementia / Q000097:blood; D005260:Female; D005470:Fluorometry; D005938:Glucocorticoids / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D002537:Intracranial Arteriosclerosis / Q000097:blood; D008297:Male; D011618:Psychotic Disorders / Q000097:blood*; D012559:Schizophrenia / Q000097:blood
D005938:Glucocorticoids; D003345:Corticosterone; D006854:Hydrocortisone