Biochemical bases of accelerated purine biosynthesis de novo in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
D000225:Adenine / Q000378:metabolism; D000227:Adenine Nucleotides / Q000494:pharmacology; D000293:Adolescent; D000328:Adult; D001264:Athetosis / Q000378:metabolism; D001706:Biopsy; D002247:Carbon Isotopes; D002648:Child; D002675:Child, Preschool; D002819:Chorea / Q000378:metabolism; D002850:Chromatography, Gel; D046508:Culture Techniques; D005246:Feedback; D005260:Female; D005347:Fibroblasts / Q000378:metabolism*; D005561:Formates / Q000378:metabolism; D006147:Guanine / Q000494:pharmacology; D006150:Guanine Nucleotides / Q000378:metabolism*; D006801:Humans; D007042:Hypoxanthines / Q000378:metabolism* / Q000494:pharmacology; D008607:Intellectual Disability / Q000378:metabolism; D008297:Male; D015122:Mercaptopurine / Q000494:pharmacology; D009711:Nucleotides / Q000378:metabolism / Q000494:pharmacology; D011687:Purines / Q000096:biosynthesis*; D012652:Self Mutilation / Q000378:metabolism; D013035:Spasm / Q000378:metabolism; D014166:Transferases / Q000378:metabolism*; D014316:Tritium
D000227:Adenine Nucleotides; D002247:Carbon Isotopes; D005561:Formates; D006150:Guanine Nucleotides; D007042:Hypoxanthines; D009711:Nucleotides; D011687:Purines; D014316:Tritium; D006147:Guanine; D015122:Mercaptopurine; D014166:Transferases; D000225:Adenine