Incorporation of carbon dioxide and acetate into the pyrrolidine ring of nicotine.
D000085:Acetates / Q000378:metabolism*; D002245:Carbon Dioxide / Q000378:metabolism*; D002247:Carbon Isotopes; D005971:Glutamates / Q000378:metabolism; D009538:Nicotine / Q000096:biosynthesis*; D010947:Plants, Toxic; D011759:Pyrrolidines; D013997:Time Factors; D014026:Nicotiana / Q000378:metabolism*
D000085:Acetates; D002247:Carbon Isotopes; D005971:Glutamates; D011759:Pyrrolidines; D002245:Carbon Dioxide; D009538:Nicotine