Study of fatal cases of Friedreich's ataxia.
A study of 82 fatal cases of Friedreich's ataxia showed that over half the patients died of heart failure while nearly three-quarters had evidence of cardiac dysfunction during life. A high incidence of diabetes mellitus (23%) was another finding, and four patients developed diabetic ketosis terminally.
D000138:Acidosis / Q000150:complications; D000293:Adolescent; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000150:complications; D002648:Child; D002675:Child, Preschool; D048909:Diabetes Complications; D004562:Electrocardiography; D004739:England; D005260:Female; D005621:Friedreich Ataxia / Q000150:complications* / Q000235:genetics / Q000401:mortality*; D006333:Heart Failure / Q000150:complications; D006801:Humans; D008136:Longevity; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D011014:Pneumonia / Q000401:mortality; D013610:Tachycardia / Q000150:complications