Hydroxyindole-O-methyl-transferase activity: effect of sympathetic nerve stimulation.
Stimulation of the preganglionic nerve trunk to the superior cervical ganglion causes a reduction in pineal hydroxyindole-O-methyl-transferase levels which is time-dependent. The results provide direct evidence for a role of afferent input in the control of pineal enzymatic activity.
D000818:Animals; D001766:Blindness; D002940:Circadian Rhythm; D004558:Electric Stimulation; D005725:Ganglia, Autonomic / Q000502:physiology; D008027:Light; D008297:Male; D008550:Melatonin / Q000096:biosynthesis; D013508:Ophthalmologic Surgical Procedures; D009900:Optic Nerve; D010870:Pineal Gland / Q000201:enzymology* / Q000294:innervation / Q000378:metabolism; D051381:Rats; D013562:Sympathectomy; D013564:Sympathetic Nervous System / Q000502:physiology*; D014166:Transferases / Q000378:metabolism*
D014166:Transferases; D008550:Melatonin