Transport of 1-aminocyclopentanecarboxylic acid from feline cerebrospinal fluid.
1-Aminocyclopentanecarboxylic acid was cleared from cerebrospinal fluid of the cat by a saturable mechanism. Clearance was inhibited by naturally occurring neutral amino acids. Carrier transport may explain the low ratio of amino acid in spinal fluid to that in plasma.
D000596:Amino Acids / Q000134:cerebrospinal fluid*; D000818:Animals; D001692:Biological Transport; D001921:Brain / Q000378:metabolism; D002247:Carbon Isotopes; D002415:Cats; D003517:Cyclopentanes; D007456:Iodine Isotopes; D007700:Kinetics; D010477:Perfusion
D000596:Amino Acids; D002247:Carbon Isotopes; D003517:Cyclopentanes; D007456:Iodine Isotopes