The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. 3. Inhibition of deoxythymidine phosphorylase by purines.
D000493:Allopurinol / Q000494:pharmacology*; D001665:Binding Sites; D002247:Carbon Isotopes; D002474:Cell-Free System; D003857:Deoxyuridine / Q000096:biosynthesis*; D003864:Depression, Chemical; D004355:Drug Stability; D005964:Glucosyltransferases / Q000037:antagonists & inhibitors*; D006358:Hot Temperature; D006801:Humans; D007042:Hypoxanthines / Q000494:pharmacology*; D007700:Kinetics; D007962:Leukocytes / Q000201:enzymology*; D015122:Mercaptopurine / Q000494:pharmacology*; D009705:Nucleosides / Q000096:biosynthesis* / Q000494:pharmacology; D011489:Protein Denaturation; D013936:Thymidine; D013941:Thymine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D014508:Urea / Q000494:pharmacology; D014970:Xanthines / Q000494:pharmacology*
D002247:Carbon Isotopes; D007042:Hypoxanthines; D009705:Nucleosides; D014970:Xanthines; D000493:Allopurinol; D014508:Urea; D015122:Mercaptopurine; D005964:Glucosyltransferases; D013941:Thymine; D013936:Thymidine; D003857:Deoxyuridine