The effect of chymotrypsin on the gastrointestinal absorption, tissue penetration, and pharmacological activity of drugs. I. Penetration of penicillin through the blood-brain and blood-retinal barriers.
D000818:Animals; D001681:Biological Assay; D001812:Blood-Brain Barrier / Q000187:drug effects*; D001923:Brain Chemistry; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002918:Chymotrypsin / Q000032:analysis / Q000494:pharmacology*; D005123:Eye / Q000032:analysis; D006168:Guinea Pigs; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D010400:Penicillin G / Q000378:metabolism*; D010406:Penicillins / Q000032:analysis; D011485:Protein Binding; D011817:Rabbits; D012160:Retina / Q000378:metabolism*
D010406:Penicillins; D002918:Chymotrypsin; D010400:Penicillin G