Phenotypic expressions of the major histocompatibility locus in man (HL-A): leukocyte antigens and mixed leukocyte culture reactivity.
The evidence is reviewed that a single genetic system, the major histocompatibility locus in man, HL-A, determines most of the antigens measured by presently available leukocyte isoantisera, and also controls reactivity in one-way mixed leucocyte culture tests. Studies in 12 families are presented to support this conclusion. Some interesting exceptions to the general typing-MLC tests correlation are presented and discussed.
D000941:Antigens / Q000032:analysis*; D005260:Female; D005826:Genetics, Medical; D006648:Histocompatibility; D006650:Histocompatibility Testing; D006801:Humans; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D010641:Phenotype; D014181:Transplantation Immunology
D000941:Antigens