Reaction of alloxan with thiol groups of proteins. Blockage of the reactivation of reduced ribonuclease.
D000496:Alloxan; D000818:Animals; D001205:Ascorbic Acid; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D010084:Oxidation-Reduction; D010179:Pancreas / Q000201:enzymology*; D011506:Proteins; D012260:Ribonucleases / Q000037:antagonists & inhibitors; D013053:Spectrophotometry; D013438:Sulfhydryl Compounds; D014443:Tyrosine
D011506:Proteins; D013438:Sulfhydryl Compounds; D014443:Tyrosine; D000496:Alloxan; D012260:Ribonucleases; D001205:Ascorbic Acid