Uridylate kinase activity: effect of isoproterenol.
Isoproterenol stimulates cell proliferation in mouse salivary glands. Prior to the stimulation of DNA synthesis, (3)H-uridine incorporation into RNA is decreased. This decreased incorporation results from a depression of uridylate kinase activity.
D000818:Animals; D002852:Chromatography, Ion Exchange; D004247:DNA / Q000096:biosynthesis*; D003864:Depression, Chemical; D007545:Isoproterenol / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D010770:Phosphotransferases / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis*; D012469:Salivary Glands / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D014316:Tritium; D014500:Uracil Nucleotides / Q000032:analysis / Q000378:metabolism; D014529:Uridine / Q000378:metabolism*
D014500:Uracil Nucleotides; D014316:Tritium; D012313:RNA; D004247:DNA; D010770:Phosphotransferases; D007545:Isoproterenol; D014529:Uridine