Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus.
The cell-free system of clinical isolates of drug-resistant Staphylococcus aureus inactivated kanamycin, and the inactivated product was identified with kanamycin-3'-phosphate, in which the C-3-OH of the 6-amino-6-deoxy-d-glucose moiety of kanamycin was phosphorylated.
D002474:Cell-Free System; D004352:Drug Resistance, Microbial; D004798:Enzymes / Q000378:metabolism; D007612:Kanamycin / Q000378:metabolism* / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*
D004798:Enzymes; D007612:Kanamycin