Retrograde amnesia produced by hippocampal spreading depression.
Injection of potassium chloride into the hippocampus produces a disruption of electrical activity; a concomitant of this disruption is a deficit in retention of conditioned suppression learned 24 hours before injection.
D000647:Amnesia / Q000209:etiology*; D000818:Animals; D003213:Conditioning, Psychological; D003864:Depression, Chemical; D004569:Electroencephalography; D006624:Hippocampus / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D008568:Memory; D009419:Nerve Tissue Proteins / Q000096:biosynthesis; D011189:Potassium Chloride / Q000494:pharmacology*; D051381:Rats
D009419:Nerve Tissue Proteins; D011189:Potassium Chloride