Toxicity, haematological effects and anti-tumour activity of epoxides derived from disubstituted hexitols. Mode of action of mannitol myleran and dibromomannitol.
D000740:Anemia / Q000139:chemically induced; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000633:toxicity*; D001002:Anuria / Q000139:chemically induced; D001791:Blood Platelet Disorders / Q000139:chemically induced; D001792:Blood Platelets / Q000187:drug effects*; D002066:Busulfan / Q000494:pharmacology*; D004988:Ethers, Cyclic / Q000494:pharmacology* / Q000633:toxicity*; D005947:Glucose / Q000494:pharmacology; D007942:Leukemia, Experimental / Q000503:physiopathology; D007962:Leukocytes / Q000187:drug effects*; D008353:Mannitol / Q000494:pharmacology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000503:physiopathology; D051381:Rats
D000970:Antineoplastic Agents; D004988:Ethers, Cyclic; D008353:Mannitol; D002066:Busulfan; D005947:Glucose