Vitamin D intoxication, with hypernatraemia, potassium and water depletion, and mental depression.
Two elderly patients suffering from manic-depressive psychosis/depressive reaction had concurrently hypercalcaemia from vitamin D intoxication. They developed hypernatraemia with severe potassium and water depletion. Hypercalcaemia was pronounced, but both patients recovered quickly and their depressive symptoms resolved following water and potassium repletion and corticosteroid therapy.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001714:Bipolar Disorder / Q000150:complications*; D003681:Dehydration / Q000209:etiology*; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D006955:Hypernatremia / Q000209:etiology*; D008297:Male; D011188:Potassium / Q000627:therapeutic use; D011191:Potassium Deficiency / Q000209:etiology*; D014807:Vitamin D / Q000009:adverse effects*
D000305:Adrenal Cortex Hormones; D014807:Vitamin D; D011188:Potassium