Estrogen-dependent increase in transfer RNA during differentiation of the chick oviduct.
Estrogenic hormones induce morphologic and biochemical differentiation in the oviduct of the immature chick. Concomitant with the hormone-stimulated tissue growth, there was an increase in 4S RNA, as judged by polyacrylamide-gel electrophoresis, and a corresponding increase in cellular transfer RNA activity, as measured by the amino acid acceptor capacity. This system may be suitable for studying the relation of hormones to transfer RNA in a differentiating tissue.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D002247:Carbon Isotopes; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004589:Electrophoresis, Disc; D004967:Estrogens / Q000502:physiology*; D005246:Feedback; D005260:Female; D005815:Genetic Code; D010057:Oviducts / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism*; D012343:RNA, Transfer / Q000032:analysis / Q000378:metabolism*; D013268:Stimulation, Chemical
D000596:Amino Acids; D002247:Carbon Isotopes; D004967:Estrogens; D004054:Diethylstilbestrol; D012343:RNA, Transfer