Kalafungin, a new antibiotic produced by Streptomyces tanashiensis strain Kala.
Kalafungin is a new antimicrobial agent obtained from the culture broth of a soil isolate of Streptomyces tanashiensis, designated Streptomyces tanashiensis strain Kala UC-5063. Kalafungin is a chemically stable, nonpolyene agent which is ex-extremely inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000302:isolation & purification*; D000981:Antiprotozoal Agents / Q000302:isolation & purification*; D002854:Chromatography, Paper; D005285:Fermentation; D006863:Hydrogen-Ion Concentration; D008854:Microscopy, Electron; D013302:Streptomyces / Q000166:cytology / Q000254:growth & development / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents