The effect of alkyl substitution in drugs. XIX. Synthesis and pharmacological properties of a series of 1-(diarylmethoxy)-3-(isopropylamino)-2-propanol hydrochlorides showing antiarrhythmic activity.
D000588:Amines / Q000494:pharmacology; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000517:prevention & control*; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D002490:Central Nervous System / Q000187:drug effects; D003315:Cornea / Q000187:drug effects; D004231:Diuresis / Q000187:drug effects; D005260:Female; D006168:Guinea Pigs; D006325:Heart Atria / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D008012:Lidocaine / Q000494:pharmacology; D008297:Male; D051379:Mice; D009132:Muscles / Q000494:pharmacology; D011802:Quinidine / Q000494:pharmacology; D051381:Rats
D000588:Amines; D000779:Anesthetics, Local; D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; D011802:Quinidine