Deamination by "transformed" mitochondrial amine oxidase of the epsilon-amino group of lysine and selective inhibition of this reaction by beta-aminopropionitrile.
D000629:Aminopropionitrile / Q000494:pharmacology; D000818:Animals; D002417:Cattle; D066298:In Vitro Techniques; D008239:Lysine / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000201:enzymology*; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009570:Nitriles / Q000494:pharmacology*; D051381:Rats
D008996:Monoamine Oxidase Inhibitors; D009570:Nitriles; D000629:Aminopropionitrile; D008995:Monoamine Oxidase; D008239:Lysine
Biochemistry. 1967 Apr;6(4):1142-8
6067864
Proc R Soc Lond B Biol Sci. 1964 Dec 15;161:153-67
14224405
Clin Pharmacol Ther. 1967 Jul-Aug;8(4):593-602
4951976
Experientia. 1966 Mar 15;22(3):157
5960880
J Exp Med. 1961 Sep 1;114:295-310
13761342
Biokhimiia. 1968 Mar-Apr;33(2):393-402
4969636
Biochem Biophys Res Commun. 1967 Jun 23;27(6):613-7
6058807
Biochem J. 1964 Apr;91(1):171-82
4953592
J Biol Chem. 1954 Jun;208(2):645-61
13174575