Gene dosage at the lactate dehydrogenase b locus in triploid and diploid teiid lizards.
Triploid parthenogenetic lizards which are heterozygous at the lactate dehydrogenase b locus show approximately two doses of the b allele and approximately one dose of the b' allele. This finding agrees with the triploid karyotype composed of two haploid complements of chromosomes indistinguishable from those of species carrying the b allele and one complement indistinguishable from that of the species which carries the b' allele. Densitometry of electrophoretic patterns of lactate dehydrogenase from heart muscle and from kidney indicates approximately equal expression of each of the b alleles in the triploid lizards. Heterozygouis diploid lizards from the same parthenogenetic species, in agreement with their karyotype, show equal doses of b and b' alleles.
D000483:Alleles; D000818:Animals; D003720:Densitometry; D004171:Diploidy; D004589:Electrophoresis, Disc; D006579:Heterozygote; D066298:In Vitro Techniques; D007527:Isoenzymes; D007668:Kidney / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008116:Lizards; D008967:Molecular Biology; D009206:Myocardium / Q000201:enzymology; D010312:Parthenogenesis; D011123:Polyploidy
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase