Actinomycin D: uptake by sea urchin eggs and embryos.
Actinomycin D is excluded from unfertilized eggs and developing embryos of the sea urchin Arbacia punctulata until the blastula hatches. The rate of uptake of actinomycin D by embryos doubles as development progresses after hatching to the gastrula stage.
D000818:Animals; D001345:Autoradiography; D002247:Carbon Isotopes; D002463:Cell Membrane Permeability; D003609:Dactinomycin / Q000378:metabolism*; D004447:Echinodermata; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D005260:Female; D005306:Fertilization; D008297:Male; D010063:Ovum / Q000378:metabolism*; D011485:Protein Binding; D013997:Time Factors
D002247:Carbon Isotopes; D003609:Dactinomycin