High-resolution autoradiography of intracellular plutonium.
Intracellular incorporation of polymeric plutonium injected into mice was demonstrated in liver and spleen by electron-microscopic auto-radiography. The observations are not inconsistent with other evidence indicating the association of plutonium with lysosomal components. Early results with a quantitative electron-microscopic technique may lead to microdosimetry of cells and cellular components.
D000818:Animals; D001345:Autoradiography; D006651:Histocytochemistry; D007275:Injections, Intravenous; D008099:Liver / Q000166:cytology*; D008247:Lysosomes; D008264:Macrophages; D051379:Mice; D008854:Microscopy, Electron; D011005:Plutonium; D011108:Polymers; D013154:Spleen / Q000166:cytology*
D011108:Polymers; D011005:Plutonium