Some effects of PCO2 and pH on nerve tissue.
1. Rat phrenic nerve preparations were used in vitro to study action potential amplitude and nerve conduction time under varying conditions of Pco(2) and sodium bicarbonate concentration in the surrounding Krebs solution.2. A correlation was found between action potential amplitude and pH but not between action potential amplitude and Pco(2).3. A better correlation was found between conduction time and pH than between conduction time and Pco(2).
D000200:Action Potentials; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D002245:Carbon Dioxide; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D009431:Neural Conduction; D010313:Partial Pressure; D010791:Phrenic Nerve / Q000502:physiology*; D051381:Rats; D013696:Temperature
D001639:Bicarbonates; D002245:Carbon Dioxide