Adrenal tyrosine hydroxylase: compensatory increase in activity after chemical sympathectomy.
Destruction of peripheral sympathetic nerve endings with 6-hydroxydopamine causes a disappearance of cardiac tyrosine hydroxylase, accompanied by a twofold increase in adrenal tyrosine hydroxylase and a small increase in phenyl-ethanolanine-N-methyl transferase. No change in adrenal catecholamine content occurs under these conditions.
D000311:Adrenal Glands / Q000187:drug effects / Q000201:enzymology* / Q000294:innervation; D000818:Animals; D002395:Catecholamines / Q000494:pharmacology*; D004298:Dopamine; D004837:Epinephrine / Q000096:biosynthesis; D006321:Heart / Q000187:drug effects / Q000294:innervation; D008297:Male; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009206:Myocardium / Q000201:enzymology; D009411:Nerve Endings / Q000187:drug effects; D009638:Norepinephrine / Q000096:biosynthesis; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects*; D014166:Transferases / Q000378:metabolism; D014443:Tyrosine
D002395:Catecholamines; D010627:Phenethylamines; D014443:Tyrosine; D006899:Mixed Function Oxygenases; D014166:Transferases; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine