Isolation and partial characterization of a staphylococcal leukocyte cytotaxin.
A factor which attracts rabbit polymorphonuclear leukocytes both in vitro and in vivo was isolated from the culture filtrate of a strain of Staphylococcus aureus. The activity of the chemotactic factor was independent of fresh serum and it was nondialyzable. Incubation of the factor with heat-inactivated human serum markedly inhibited its chemotactic property. The factor was heat-labile (80 C, 10 min) in the crude culture filtrate but was heat-stable when partially purified.
D000818:Animals; D001769:Blood; D003585:Cell Biology; D002633:Chemotaxis; D003470:Culture Media / Q000032:analysis; D006358:Hot Temperature; D006801:Humans; D007962:Leukocytes; D011817:Rabbits; D013210:Staphylococcus / Q000032:analysis
D003470:Culture Media