Lecithin aerosols generated ultrasonically above 25 degrees C.
Dl-Dipalmitoyl-alpha-lecithin, suspended in 0.15-molar sodium chloride solution by sonic cavitation at 20 kilohertz, can be aerosolized by an 800-kilohertz ultrasonic generator only at temperatures above 25 degrees C. The aerosol thus produced is exceptionally stable against evaporation even at particle radii of 0.1 to 0.6 micron; this suggests applicability to the therapy of pulmonary disorders.
D000336:Aerosols; D001698:Biomedical Engineering; D008171:Lung Diseases / Q000188:drug therapy; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D013500:Surface Tension; D013696:Temperature; D014465:Ultrasonics
D000336:Aerosols; D010713:Phosphatidylcholines