Preferential synthesis of ferritin and albumin by different populations of liver polysomes.
Free polysomes and a mixture of free and membrane-attached polysomes were isolated separately from rat liver, and each was added to a cell-free, protein-synthesizing system. The free polysomes showed a greater capacity than the mixed polysome population for incorporation of (14)C-leucine into ferritin, whereas the reverse was true for (14)C-leucine incorporation into albumin.
D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D002247:Carbon Isotopes; D002474:Cell-Free System; D005293:Ferritins / Q000096:biosynthesis*; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D010452:Peptide Biosynthesis; D051381:Rats; D012270:Ribosomes / Q000378:metabolism*; D012709:Serum Albumin / Q000096:biosynthesis*
D000596:Amino Acids; D002247:Carbon Isotopes; D012709:Serum Albumin; D005293:Ferritins; D007930:Leucine