Irreversible enzyme inhibitors. CXXXIV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonyl-phenylureido)phenoxymethyl]pyrimidine.
D000818:Animals; D001555:Benzene Derivatives; D001665:Binding Sites; D002219:Carbamates; D055598:Chemical Phenomena; D002621:Chemistry; D002713:Chlorine; D005459:Fluorides; D005493:Folic Acid Antagonists; D007939:Leukemia L1210 / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008745:Methylation; D051379:Mice; D011743:Pyrimidines / Q000138:chemical synthesis; D013451:Sulfonic Acids / Q000138:chemical synthesis; D013997:Time Factors
D001555:Benzene Derivatives; D002219:Carbamates; D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013451:Sulfonic Acids; D002713:Chlorine; D005459:Fluorides