The cryptic nature of hepatic microsomal sulphite oxidase.
1. The activity of rat liver microsomal sulphite oxidase (EC 1.8.3.1) was increased several-fold on aging of microsomes, on delipidation by extraction with acetone or on solubilization with deoxycholate, suggesting its existence in a cryptic state. 2. In rat liver most of the sulphite oxidase was present in the nuclear fraction and only a small portion in the microsomes. 3. Microsomal sulphite oxidase activity was low in the developing embryo and increased rapidly after birth.
D000096:Acetone; D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D001647:Bile Acids and Salts; D002467:Cell Nucleus / Q000201:enzymology; D004622:Embryo, Mammalian / Q000201:enzymology; D008055:Lipids; D008099:Liver / Q000201:enzymology*; D008861:Microsomes / Q000201:enzymology*; D010088:Oxidoreductases / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D012996:Solutions
D001647:Bile Acids and Salts; D008055:Lipids; D012996:Solutions; D000096:Acetone; D010088:Oxidoreductases