Goblet cell increase in rat bronchial epithelium after exposure to cigarette and cigar tobacco smoke.
Both cigar and cigarette tobacco produce an increase in the number of goblet cells in the rat trachea and intrapulmonary airways over a six-week period. The increase in goblet cells is similar for the two types of tobacco; in both it is proportional to increase in dose and greatest in the proximal intrapulmonary airways.
D000818:Animals; D001835:Body Weight; D001980:Bronchi / Q000187:drug effects* / Q000473:pathology; D004848:Epithelium / Q000187:drug effects*; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008297:Male; D010947:Plants, Toxic; D051381:Rats; D012907:Smoking; D014026:Nicotiana; D014132:Trachea / Q000187:drug effects / Q000473:pathology