Glucose-dependent secretion and destruction of hydrogen peroxide by Mycoplasma pneumoniae.
The secretion of H(2)O(2) by Mycoplasma pneumoniae and M. gallisepticum was measured with the new catalase-aminotriazole method. Peroxide secretion by the mycoplasmas was stimulated by glucose. When catalase and aminotriazole were omitted and exogenous H(2)O(2) was added to the mycoplasmas, a loss in H(2)O(2) was noted with time; the addition of glucose speeded the disappearance of H(2)O(2). The presence of this peroxidase-like activity in the mycoplasmas explains an observed failure of H(2)O(2) to accumulate freely in the suspension medium.
D002374:Catalase; D005947:Glucose / Q000494:pharmacology*; D006861:Hydrogen Peroxide / Q000032:analysis / Q000378:metabolism*; D009174:Mycoplasma / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D010544:Peroxidases / Q000378:metabolism; D014230:Triazoles
D014230:Triazoles; D006861:Hydrogen Peroxide; D010544:Peroxidases; D002374:Catalase; D005947:Glucose