Teleostean urophysis: stimulation of contractions of bladder of the trout Salmo gairdnerii.
A new activity of the teleost caudal neurosecretory system is described. Extracts of the urophysis of the mudsucker Gillichthys mirabilis and of the trout Salmo gairdnerii cause rhythmic contractions of the isolated urinary bladder of the trout. The dose-related response provides the basis for a quantitative bioassay of this urophysial principle.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D005260:Female; D005399:Fishes; D007421:Intestine, Small / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects*; D009489:Neurosecretion; D010121:Oxytocin / Q000494:pharmacology; D051381:Rats; D012487:Salmonidae; D012701:Serotonin / Q000494:pharmacology; D013864:Thioglycolates / Q000494:pharmacology; D014020:Tissue Extracts / Q000494:pharmacology*; D001743:Urinary Bladder / Q000187:drug effects / Q000502:physiology*; D014599:Uterus / Q000187:drug effects; D014667:Vasopressins / Q000494:pharmacology; D014668:Vasotocin / Q000494:pharmacology
D013864:Thioglycolates; D014020:Tissue Extracts; D014667:Vasopressins; D012701:Serotonin; D010121:Oxytocin; D000109:Acetylcholine; D014668:Vasotocin