Post-partum hypercalcaemia in treated hypoparathyroidism.
Two patients with post-thyroidectomy hypoparathyroidism were observed throughout three pregnancies. Their normal maintenance treatment with vitamin D remained unaltered. Serum calcium levels remained normal until shortly before delivery but rose rapidly in the immediate postpartum period to peak levels of 7.8, 6.0, and 6.8 mEq/l. while still on normal or reduced maintenance treatment. This apparent increased sensitivity to vitamin D after delivery persisted for as long as three months.
D000328:Adult; D002118:Calcium / Q000097:blood; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D007011:Hypoparathyroidism / Q000150:complications*; D011247:Pregnancy; D011644:Puerperal Disorders; D013965:Thyroidectomy / Q000009:adverse effects*; D013997:Time Factors; D014807:Vitamin D / Q000009:adverse effects / Q000627:therapeutic use
D014807:Vitamin D; D002118:Calcium