Alcohol and amitriptyline effects on skills related to driving behavior.
Three motor-skill tests related to driving ability were given to 21 healthy young volunteers after administration of various combinations of amitriptyline, placebo, and alcohol. It was found that the tricylic antidepressant added to the deleterious effects of alcohol.
D000328:Adult; D000434:Alcoholic Beverages; D000639:Amitriptyline / Q000494:pharmacology*; D001334:Automobile Driving; D004357:Drug Synergism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D009048:Motor Skills / Q000187:drug effects*; D010919:Placebos
D010919:Placebos; D000639:Amitriptyline; D000431:Ethanol