Cytogenetic effects of cyclamates on human cells in vitro.
Chromosome studies on human cells in vitro have shown that the artificial sweeteners, sodium and calcium cyclamate, can induce chromosome breaks in vitro in human cells, in both leukocyte and monolayer cultures.
D002277:Carcinoma; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects*; D046508:Culture Techniques; D003582:Cytogenetics; D006801:Humans; D007822:Laryngeal Neoplasms; D007962:Leukocytes / Q000166:cytology* / Q000187:drug effects; D013268:Stimulation, Chemical; D013549:Sweetening Agents / Q000494:pharmacology*
D013549:Sweetening Agents