Adrenergic blood pressure responses in the shark.
Both nurse and lemon sharks recovered slowly from the pressor effect of epinephrine and from the depressor effect of isoproterenol. The recovery time increased with the dose of epinephrine. Grading of dosage and the use of dibenzyline revealed that these species exhibit alpha and beta adrenergic vascular responses in a manner qualitatively similar but quantitatively dissimilar to that for mammals.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D003864:Depression, Chemical; D004837:Epinephrine / Q000494:pharmacology*; D007545:Isoproterenol / Q000494:pharmacology*; D010643:Phenoxybenzamine / Q000494:pharmacology; D011955:Receptors, Drug; D011984:Sensory Receptor Cells / Q000502:physiology*; D012754:Sharks / Q000502:physiology*; D013268:Stimulation, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*
D011955:Receptors, Drug; D010643:Phenoxybenzamine; D007545:Isoproterenol; D004837:Epinephrine