Mechanism of growth inhibition by 5-fluorouracil. Reversal studies with pyrimidine metabolites in vitro.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D046508:Culture Techniques; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003864:Depression, Chemical; D005472:Fluorouracil / Q000633:toxicity*; D051379:Mice; D009711:Nucleotides / Q000096:biosynthesis; D009963:Orotic Acid / Q000494:pharmacology*; D012334:RNA, Neoplasm / Q000096:biosynthesis; D013936:Thymidine / Q000494:pharmacology*; D014529:Uridine / Q000494:pharmacology*
D004273:DNA, Neoplasm; D009711:Nucleotides; D012334:RNA, Neoplasm; D009963:Orotic Acid; D005472:Fluorouracil; D013936:Thymidine; D014529:Uridine