Sweat in schizophrenic patients: identification of the odorous substance.
The substance causing the peculiar odor in sweat of schizophrenic patients has been isolated and identified as trans-3-methyl-2-hexenoic acid by gas chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy. The natural and the synthetic compounds were cleaves across the double bond to give 2-pentanone and oxalic acid, thereby confirming the structure.
D002208:Caproates / Q000302:isolation & purification*; D002849:Chromatography, Gas; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009812:Odorants / Q000032:analysis*; D012559:Schizophrenia / Q000378:metabolism*; D013057:Spectrum Analysis; D013237:Stereoisomerism; D013542:Sweat / Q000032:analysis*
D002208:Caproates