Indole(ethyl)amine N-methyltransferase in the brain.
An enzyme which N-methylates various indole(ethyl)amine substrates was isolated from brain, separated from the pituitary and the pineal glands. It appeared localized in the supernatant and synaptosomal areas after discontinuous sucrose-gradient ultracentrifugation. This is the first demonstration of the enzyme in brain.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001923:Brain Chemistry; D002499:Centrifugation, Density Gradient; D002645:Chickens; D008745:Methylation; D014166:Transferases / Q000302:isolation & purification*; D014363:Tryptamines / Q000378:metabolism*
D014363:Tryptamines; D014166:Transferases