[A new group of competitive divalent Ca-antagonists (iproveratril, D 600, prenylamine) with potent inhibitory effects on electromechanical coupling in mammalian myocardium].
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001696:Biomechanical Phenomena; D002118:Calcium / Q000037:antagonists & inhibitors*; D003864:Depression, Chemical; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects / Q000502:physiology*; D006439:Hemodynamics; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009570:Nitriles / Q000494:pharmacology*; D010210:Papillary Muscles / Q000502:physiology; D011299:Prenylamine / Q000494:pharmacology*; D014665:Vasodilator Agents / Q000494:pharmacology*; D014700:Verapamil / Q000494:pharmacology
D000889:Anti-Arrhythmia Agents; D009570:Nitriles; D014665:Vasodilator Agents; D014700:Verapamil; D011299:Prenylamine; D002118:Calcium
Eine neue Gruppe kompetitiver zweiwertiges Ca-Antagonisten (Iproveratril, D 600, Prenylamin) mit starken Hemmeffekten auf die elektromechanische Koppelung im Warmblüter-Myokard.