The role of bioactivation on the pharmacology of the potent monoamine oxidase inhibitor 5-oxo-N-(D-trans-2-phenylcyclopropyl)-L-2-pyrrolidine-carboxamide (EX-4883).
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D006321:Heart / Q000187:drug effects; D051379:Mice; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology*; D009541:Nictitating Membrane / Q000187:drug effects; D011759:Pyrrolidines / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D014191:Tranylcypromine / Q000494:pharmacology* / Q000633:toxicity
D008996:Monoamine Oxidase Inhibitors; D011759:Pyrrolidines; D014191:Tranylcypromine