Irreversible enzyme inhibitors. CLIX. Effect of substitution on transport and isozyme specificity of p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)-o-chlorophenoxyacetamido-benzenesulfonyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D046508:Culture Techniques; D005493:Folic Acid Antagonists; D007939:Leukemia L1210 / Q000201:enzymology* / Q000378:metabolism; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D051379:Mice; D014227:Triazines / Q000494:pharmacology*
D005493:Folic Acid Antagonists; D014227:Triazines