Why sulphonamides, when combined with 2-4-diamino-pyrimidines, are effective in sulphonamide-resistant gonorrhoea.
D004357:Drug Synergism; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008956:Models, Chemical; D011743:Pyrimidines / Q000627:therapeutic use*; D013449:Sulfonamides / Q000627:therapeutic use*
D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013449:Sulfonamides