Uptake of monosaccharides by guinea-pig cerebral-cortex slices.
By the use of 1mm-iodoacetate to inhibit glycolysis in guinea-pig cerebral tissue slices, the kinetics of the uptake of monosaccharides on transfer of tissue from 0 degrees to 37 degrees were studied. d-Ribose, d-galactose, d-mannose, l-sorbose, and d-fructose showed diffusion kinetics, whereas 2-deoxy-d-glucose, d-glucose, d-arabinose and d-xylose showed saturation kinetics.
D000818:Animals; D001089:Arabinose / Q000378:metabolism; D001692:Biological Transport; D001693:Biological Transport, Active; D002540:Cerebral Cortex / Q000378:metabolism*; D003864:Depression, Chemical; D004058:Diffusion; D005632:Fructose / Q000378:metabolism; D005690:Galactose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis / Q000187:drug effects; D006168:Guinea Pigs; D006601:Hexoses / Q000378:metabolism*; D066298:In Vitro Techniques; D007461:Iodoacetates / Q000494:pharmacology; D007700:Kinetics; D008358:Mannose / Q000378:metabolism; D008566:Membranes; D010429:Pentoses / Q000378:metabolism*; D010539:Permeability; D012266:Ribose / Q000378:metabolism; D013013:Sorbose / Q000378:metabolism; D013237:Stereoisomerism; D014994:Xylose / Q000378:metabolism
D006601:Hexoses; D007461:Iodoacetates; D010429:Pentoses; D005632:Fructose; D012266:Ribose; D014994:Xylose; D001089:Arabinose; D005947:Glucose; D013013:Sorbose; D008358:Mannose; D005690:Galactose