Potentiation of insulin action in normal subjects by a pituitary polypeptide.
A pituitary polypeptide, acceleratory polypeptide-growth hormone (ACG), has been found to increase the sensitivity of fasting normal people to intravenous insulin. It is suggested that diminished activity of this polypeptide-or increased activity of another polypeptide, inhibitory polypeptide-growth hormone (ING)-may have a role in the genesis of diabetes mellitus.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000209:etiology; D004357:Drug Synergism; D005215:Fasting; D013006:Growth Hormone / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D007328:Insulin / Q000494:pharmacology*; D010455:Peptides / Q000494:pharmacology*
D001786:Blood Glucose; D007328:Insulin; D010455:Peptides; D013006:Growth Hormone