Induction of liver microsomal cortisol 6beta-hydroxylase by diphenylhydantoin or phenobarbital: an explanation for the increased excretion of 6-hydroxycortisol in humans treated with these drugs.
D000818:Animals; D002854:Chromatography, Paper; D006168:Guinea Pigs; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008099:Liver / Q000166:cytology*; D008861:Microsomes / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000096:biosynthesis*; D010634:Phenobarbital / Q000494:pharmacology* / Q000627:therapeutic use; D010672:Phenytoin / Q000494:pharmacology* / Q000627:therapeutic use; D014556:Urine
D010672:Phenytoin; D006899:Mixed Function Oxygenases; D006854:Hydrocortisone; D010634:Phenobarbital