The induction of cross-links in soluble rat skin collagen in vitro.
1. Starch-gel electrophoresis was used to investigate the subunit composition of salt-soluble and acid-soluble rat skin collagen. 2. Cross-linkage of collagen subunits in vitro was performed (a) when in fibrillar form and (b) when in solution. In the former case the increase in number of cross-links appeared to be predominantly intermolecular and in the latter case predominantly intramolecular.
D000143:Acids; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003094:Collagen; D004586:Electrophoresis; D005782:Gels; D051381:Rats; D012492:Salts; D012867:Skin; D012995:Solubility; D012996:Solutions; D013213:Starch; D013696:Temperature
D000143:Acids; D005782:Gels; D012492:Salts; D012996:Solutions; D013213:Starch; D003094:Collagen
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