Anesthesia of Artemia larvae: method for quantitative study.
Potency of anesthetics is quantitatively measured with laboratory-hatched larvae of the brine shrimp Artemia salina. Statistical fluctuations are minimized in that 100,000 animals are used to determine a single median anesthetic dose value. The technique was developed to study molecular mechanisms of general anesthesia.
D000768:Anesthesia, General / Q000295:instrumentation*; D000777:Anesthetics / Q000494:pharmacology*; D002725:Chloroform / Q000494:pharmacology*; D003445:Crustacea / Q000187:drug effects*; D003521:Cyclopropanes / Q000494:pharmacology*; D004357:Drug Synergism; D005019:Ethyl Ethers / Q000494:pharmacology*; D006221:Halothane / Q000494:pharmacology*; D066298:In Vitro Techniques
D000777:Anesthetics; D003521:Cyclopropanes; D005019:Ethyl Ethers; D002725:Chloroform; D006221:Halothane