[Idiopathic hypoparathyroidsm: provocation of a tetanic seizure by the injection of a mercurial diuretic].
Idiopathic hypoparathyroidism was diagnosed in a 55-year-old patient following rather unusual circumstances: he informed the emergency ward physician attending him for congestive cardiac insufficiency consequent to coronary cardiopathy that on the two preceding occasions when such insufficiency had been relieved by the injection of a diuretic, a tetanic seizure had ensued which was corrected by intravenous administration of calcium. Treatment of the cardiac insufficiency was nonetheless instituted with the mercurial diuretic: tetany appeared a few hours later, subsiding after intravenous injection of calcium. The various possible ways in which a tetanic seizure may be triggered by a mercurial diuretic are discussed.
D002118:Calcium / Q000627:therapeutic use; D004562:Electrocardiography; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D007011:Hypoparathyroidism / Q000175:diagnosis*; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009941:Organomercury Compounds / Q000009:adverse effects*; D013746:Tetany / Q000209:etiology*
D009941:Organomercury Compounds; D002118:Calcium
Can Med Assoc J. 1957 Jul 1;77(1):45-53
13437270
Pediatrics. 1955 Dec;16(6):848-56
13273124
Medicine (Baltimore). 1958 Dec;37(4):317-52
13621989
Can Med Assoc J. 1964 Feb 8;90:414-20
14123666
N Engl J Med. 1957 Apr 18;256(16):734-9
13451928
Hypoparathyroïdie idiopathique: provocation d'une crise tétanique par l'injection d'un diurétique mercuriel.