Lymphoma growth in vivo: electronic discrimination between tumor and stroma cells.
Moloney lymphoma cells are larger than normal cells of mouse spleen, lymph-node, and thymus. Use of electronic cell-size anaylsis in conjunction with specific immunocytolysis permits difjerential counting of host and tumor cells. Increase of lymphoma cells occurs first in spleen and then in lymph nodes; in thymus it occurs only during the terminal stages of tumor growth.
D000818:Animals; D066298:In Vitro Techniques; D008198:Lymph Nodes / Q000166:cytology; D008223:Lymphoma / Q000473:pathology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000473:pathology*; D013154:Spleen / Q000166:cytology; D013950:Thymus Gland / Q000166:cytology