Relationship between intracellular amino acids and protein synthesis in the extensor digitorum longus muscle of rats.
1. The incorporation into protein, and the accumulation into the free amino acid pools, of radioactive l-leucine and glycine was studied in rat extensor digitorum longus muscle. 2. The tissue was incubated first with (14)C-labelled and then with (3)H-labelled amino acid. 3. The experimental results were consistent with a model based on the premise that the amino acids in protein were incorporated directly from the extracellular pool.
D000818:Animals; D002247:Carbon Isotopes; D005998:Glycine / Q000378:metabolism*; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism*; D008297:Male; D008956:Models, Chemical; D009132:Muscles / Q000378:metabolism*; D014176:Protein Biosynthesis; D051381:Rats; D014316:Tritium
D002247:Carbon Isotopes; D014316:Tritium; D007930:Leucine; D005998:Glycine
Biochem J. 1968 Oct;109(4):507-15
5683503
Biochim Biophys Acta. 1963 Jun 4;71:664-75
13974899
Biochim Biophys Acta. 1966 Jul 27;124(1):62-70
5966723
Clin Sci. 1968 Oct;35(2):287-305
5721233
Biochem J. 1958 Feb;68(2):252-61
13522610
Endocrinology. 1964 Jul;75:113-9
14198282
Biochem J. 1961 Oct;81:135-47
14469128
Biochim Biophys Acta. 1961 Aug 19;51:519-24
14456225
Nature. 1964 Jul 4;203:17-9
14198840
J Biol Chem. 1954 Dec;211(2):915-26
13221597
Nature. 1962 Mar 3;193:821-3
13906416
J Biol Chem. 1963 Nov;238:3686-99
14109206
Biochim Biophys Acta. 1965 May 4;100:609-12
14347962
Biochem J. 1965 Oct;97(1):272-6
16749114
J Biol Chem. 1957 Feb;224(2):681-93
13405896
Biochim Biophys Acta. 1968 Jan 3;150(1):92-103
5642638
Am J Physiol. 1964 Mar;206:618-20
14160994
Biochem J. 1966 Mar;98(3):711-9
5911521
Biochim Biophys Acta. 1963 Sep 10;74:659-66
14078929
J Biol Chem. 1963 Aug;238:2663-8
14063289
Biochem J. 1963 Nov;89:202-9
14084603
Biochim Biophys Acta. 1964 Aug 19;90:291-300
14223710
Biochem J. 1966 Oct;101(1):135-45
4382008