Studies on the medicinal chemistry of oxoquinazolines. II. Synthesis and local anaesthetic activity of homologous derivatives of 1,2,3,4-tetrahydro-2,4-dioxoquinazoline and 3,4-dihydro-4-oxoquinazoline.
D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D001001:Anura; D055598:Chemical Phenomena; D002621:Chemistry; D003315:Cornea / Q000187:drug effects; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008012:Lidocaine / Q000494:pharmacology; D051379:Mice; D009336:Necrosis; D011799:Quinazolines / Q000009:adverse effects / Q000138:chemical synthesis* / Q000494:pharmacology* / Q000633:toxicity; D011817:Rabbits; D012584:Sciatic Nerve / Q000187:drug effects; D014202:Tremor
D000779:Anesthetics, Local; D011799:Quinazolines; D008012:Lidocaine