Stuttering. The effect of treatment with D-amphetamine and a tranquilizing agent, trifluoperazine. A preliminary report on an uncontrolled study.
In an institution for the mentally retarded, an uncontrolled study was made on the effects of d-amphetamine, d-amphetamine followed by trifluoperazine, and of combined d-amphetamine and trifluoperazine on stuttering. Of 28 patients to whom d-amphetamine was given, 14 showed improvement after one month's treatment. Eight more showed improvement when trifluoperazine was given for one month to those who did not improve on d-amphetamine. In many cases, improvement was sustained at least six months after treatment was discontinued. Treatment with d-amphetamine was apparently more effective in patients with functional than with organic retardation.
D003913:Dextroamphetamine / Q000627:therapeutic use*; D006801:Humans; D013342:Stuttering / Q000188:drug therapy*; D014268:Trifluoperazine / Q000627:therapeutic use*
D014268:Trifluoperazine; D003913:Dextroamphetamine
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13113418
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13151880
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13673285
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13893193
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14048992