Synchronization of mammalian cells with tritiated thymidine.
Short exposures of mammalian cells to tritiated thymidine of high specific activity destroys the proliferative capacity of mammalian cells. Since the killing is limited to cells that have synthesized DNA in the presence of the labeled compound, an exposure duration of less than one generation can yield a synchronized population.
D002455:Cell Division / Q000528:radiation effects*; D046508:Culture Techniques; D004247:DNA / Q000096:biosynthesis*; D007739:L Cells; D013936:Thymidine; D014316:Tritium
D014316:Tritium; D004247:DNA; D013936:Thymidine