Proteins and disulfide groups in the aggregation of dissociated cells of sea sponges.
A sponge extract that produced specific aggregation of dissociated cells was treated with various enzyme preparations to determine which enzymes would destroy its aggregating properties. The results indicate that proteins play a key role in the aggregating effect of the extract on dissociated, glutaraldehyde-fixed sponge cells. Further studies confirm the necessity of calcium for the aggregation and indicate the necessity of intact disulfide groups.
D000818:Animals; D002118:Calcium; D002449:Cell Aggregation; D055598:Chemical Phenomena; D002621:Chemistry; D004626:Embryology; D010450:Endopeptidases / Q000494:pharmacology; D066298:In Vitro Techniques; D011161:Porifera / Q000166:cytology*; D011506:Proteins; D013440:Sulfides
D011506:Proteins; D013440:Sulfides; D010450:Endopeptidases; D002118:Calcium