Galactose conversion to D-xylulose: an alternate route of galactose metabolism.
Galactose dehydrogenase, a soluble enzyme of the mammalian liver, catalyzes the conversion of galactose to galactonic acid. This reaction, together with the subsequent formation of 3-ketogalactonic acid which can be decarboxylated to yield d-xylulose, is a newly discovered pathway for the metabolism of galactosee. This pathway may account for the oxidation of galactose observed in pathients with galactosemia.
D000429:Alcohol Oxidoreductases; D000818:Animals; D005690:Galactose / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D010429:Pentoses / Q000378:metabolism*; D051381:Rats
D010429:Pentoses; D000429:Alcohol Oxidoreductases; D005690:Galactose