Antibody synthesis initiated in vitro by paired explants of spleen and thymus.
Primary in vitro synthesis of antibody has been achieved with a mouse spleen-thymus organ culture system 54 hours after it was incubated for 18 hours with coliphage R17.
D000818:Animals; D000917:Antibody Formation; D003090:Coliphages; D046508:Culture Techniques; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D051379:Mice; D009500:Neutralization Tests; D013154:Spleen / Q000502:physiology*; D013950:Thymus Gland / Q000502:physiology*
D007074:Immunoglobulin G; D007075:Immunoglobulin M