Marrow dysplasia with C trisomy and anomalies of the granulocyte nuclei.
An unusual case of bone marrow dysplasia is reported. The features of particular interest are the very high incidence of nuclear drumsticks on the polymorphs, a curious appearance of these same nuclei on electron microscopy, and C trisomy of the bone marrow cells; it is possible that the condition resulted from gold and/or x-ray treatment.
D000368:Aged; D001853:Bone Marrow; D001854:Bone Marrow Cells; D001855:Bone Marrow Diseases / Q000473:pathology*; D001856:Bone Marrow Examination; D002467:Cell Nucleus; D002875:Chromosomes; D005260:Female; D006046:Gold / Q000009:adverse effects; D006801:Humans; D007621:Karyotyping; D007962:Leukocytes; D008854:Microscopy, Electron; D011878:Radiotherapy / Q000009:adverse effects; D014314:Trisomy
D006046:Gold