Toxic fluorine compounds. The use of the omega-fluorine atom in the study of the metabolism of fatty acids containing ethyl, n-propyl and isopropyl branches.
1. Some omega-fluoroalkanoic acids containing a branched ethyl, n-propyl or isopropyl group in the alpha- or beta-position have been prepared. 2. A study of the toxicity of these acids revealed that the ethyl group partially inhibited, and the n-propyl and isopropyl groups completely inhibited, the normal processes of oxidative degradation.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005227:Fatty Acids / Q000378:metabolism* / Q000633:toxicity; D005461:Fluorine / Q000378:metabolism* / Q000633:toxicity; D008314:Malonates / Q000378:metabolism; D051379:Mice
D005227:Fatty Acids; D008314:Malonates; D005461:Fluorine