The presence in Penicillium funiculosum of an inhibitor to the antiviral agent helenine.
The present findings indicate that the wide fluctuation observed in the antiviral activity of various crude helenine preparations may be attributable to the presence of varying amounts of inhibitor. Antiviral activity could be enhanced by removal of the inhibitor. A meaningful value for helenine titer in a preparation clearly should be determined in the inhibitor-free zone.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000998:Antiviral Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D010407:Penicillium; D012672:Semliki forest virus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000998:Antiviral Agents