Lithium's failure to replace sodium in mammalian sympathetic ganglia.
Ganglionic responses to electrical stimulation, acetylcholine, and potassium ions were studied in superior cervical ganglia of. cats perfused with media containing lithium chloride instead of sodium chloride. In lithium-Locke, ganglionic transmission and depolarization evoked by acetylcholine were blocked completely but reversibly, while the depolarization produced by potassium ions was unaltered.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005725:Ganglia, Autonomic / Q000502:physiology*; D008094:Lithium; D009431:Neural Conduction / Q000502:physiology*; D009448:Neurochemistry; D010477:Perfusion; D011188:Potassium / Q000494:pharmacology; D012964:Sodium
D008094:Lithium; D012964:Sodium; D000109:Acetylcholine; D011188:Potassium