Primary-type antibody response in vitro.
Organ cultures of lymph nodes obtained from nonimmunized rabbits were incubated with bacteriophage d, X174; as a result, 19S antibody was produced first, and then 7S antibody. Differences between this response and the secondary response to d? X174 induced in vitro suggest that the foriiier is a primary response.
D000818:Animals; D000917:Antibody Formation; D001435:Bacteriophages; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D066298:In Vitro Techniques; D008198:Lymph Nodes / Q000502:physiology; D011817:Rabbits
D007074:Immunoglobulin G; D007075:Immunoglobulin M