The histological changes characteristic of the transition of prostatic hyperplasia into cancer.
D000368:Aged; D006801:Humans; D006965:Hyperplasia / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011469:Prostatic Diseases / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*