Circadian rhythm for tryptophan pyrrolase activity and its circulating substrate.
Hepatic tryptophan pyrrolase and its circulating substrate, whole blood tryptophan, have a circadian rhythmicity in mice. Intact adrenocortical function is required for the normal rhythmicity of both enzyme and substrate although an altered but less apparent rhythm persists in the adrenalectomized state.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D002940:Circadian Rhythm; D008029:Lighting; D008099:Liver / Q000201:enzymology*; D008297:Male; D051379:Mice; D010105:Oxygenases / Q000378:metabolism*; D014364:Tryptophan / Q000097:blood; D014366:Tryptophan Oxygenase / Q000378:metabolism
D014364:Tryptophan; D010105:Oxygenases; D014366:Tryptophan Oxygenase