Ciliastatic components in the gas phase of cigarette smoke.
The gas phase of cigarette smoke, separated into its components by gas chromatography, was passed across a ciliated specimen. The acetaldehyde, acrolein, and hydrogen cyanide produced strong inhibition of the ciliary beat. A filter which removed most of the acetaldehyde and acrolein from smoke did not reduce the inhibitory effect of the gas phase of that smoke, whereas a filter that removed most of the hydrogen cyanide did reduce inhibition.
D000447:Aldehydes / Q000494:pharmacology; D000818:Animals; D002849:Chromatography, Gas; D002923:Cilia / Q000187:drug effects / Q000502:physiology*; D003486:Cyanides / Q000494:pharmacology; D005374:Filtration; D008974:Mollusca; D010947:Plants, Toxic; D012907:Smoking; D014026:Nicotiana / Q000032:analysis*
D000447:Aldehydes; D003486:Cyanides