Comparative detoxication. The detoxication of aromatic acids by invertebrates: detection of agmatine conjugates in scorpions.
1. Benzoic acid and p-nitrobenzoic acid were converted in the scorpion Palamnaeus into N(1)-benzoylagmatine and N(1)-p-nitrobenzoylagmatine. 2. Some benzoyl- and p-nitrobenzoyl-arginine were also formed and these compounds were probable precursors of the agmatine derivatives. 3. p-Nitrobenzoyl- and p-aminobenzoyl-arginine were formed in millipedes dosed with the aromatic acids. 4. Woodlice excreted p-amino- and p-nitro-benzoic acid as their glycine conjugates and no conjugation could be found in the crab Gecarcinus and a freshwater crayfish Astacus.
D000818:Animals; D001181:Arthropods / Q000302:isolation & purification; D001565:Benzoates / Q000378:metabolism*; D001711:Biotransformation; D002854:Chromatography, Paper; D003445:Crustacea / Q000378:metabolism; D006146:Guanidines / Q000378:metabolism*; D066298:In Vitro Techniques; D010828:Physiology, Comparative; D012605:Scorpions / Q000378:metabolism*; D013987:Ticks / Q000378:metabolism
D001565:Benzoates; D006146:Guanidines