Diabetes, a new mutation in the mouse.
Diabetes (db), which occurred in an inbred strain of mouse, is inherited as a unit autosomal recessive and is characterized by a metabolic disturbance resembling diabetes mellitus in man. Abnormal deposition of fat at 3 to 4 weeks of age is followed shortly by hyperglycemia, polyuria, and glycosuria. Accompanying morphological changes in the islets of Langerhans suggest neogenesis to compensate for insulin depletion.
D000818:Animals; D001786:Blood Glucose; D001835:Body Weight; D003920:Diabetes Mellitus / Q000235:genetics*; D005260:Female; D008297:Male; D051379:Mice; D009154:Mutation
D001786:Blood Glucose