Rubella virus: growth and cytopathic effect in primary cultures of cells of rabbit embryos.
Primary cultures of rabbit (New Zealand white) embryo cells support growth of rubella virus. Distinct cytopathic changes are discernible within 6 to 8 days after inoculation. This cell system has been successful for the recovery of rubella virus from clinical materials and the demonstration of neutralizing antibody in patient serum.
D000818:Animals; D004622:Embryo, Mammalian; D006383:Hemadsorption Inhibition Tests; D006386:Hemagglutination Tests; D066298:In Vitro Techniques; D009500:Neutralization Tests; D011817:Rabbits; D012412:Rubella virus / Q000302:isolation & purification* / Q000472:pathogenicity; D014776:Virus Cultivation