The effect of carbon tetrachloride on the lipoproteins of rat-liver cell sap and serum.
1. The lipoproteins of the liver cell sap can be resolved by paper electrophoresis into five components. Almost two-thirds of the total lipid, cholesterol and phospholipid are present in the slowest- and the fastest-moving components. 2. There is a two- to three-fold increase in the lipid content of the liver cell sap after the administration of carbon tetrachloride. 3. The cholesterol and phospholipid contents of the serum alpha- and beta-lipoproteins separated by paper electrophoresis fall after treatment with carbon tetrachloride, whereas the total lipid content of that fraction that remains at the origin rises.
D000818:Animals; D001769:Blood; D001797:Blood Protein Electrophoresis; D002251:Carbon Tetrachloride / Q000494:pharmacology*; D002784:Cholesterol / Q000032:analysis; D005260:Female; D008055:Lipids / Q000032:analysis; D008074:Lipoproteins / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D008297:Male; D010743:Phospholipids / Q000032:analysis; D051381:Rats
D008055:Lipids; D008074:Lipoproteins; D010743:Phospholipids; D002784:Cholesterol; D002251:Carbon Tetrachloride