Role of differential air pressure zones in the control of aerosols in a large animal isolation facility.
The uncontrolled transmission of hog cholera in a large animal isolation facility, designed to control the movement of aerosols within and between individual wings of a multiunit building, indicated the need for a critical study of aerosol behavior under existing conditions of operation. Studies with aerosols of Escherichia coli B T3 bacteriophage (T3 coliphage) conclusively demonstrated the impossibility of obtaining the desired control by means of a "static" air balance relationship between adjacent areas within the facility. Modifications needed to provide the desired control of the air-handling system are outlined and discussed.
D000336:Aerosols; D000391:Air Microbiology; D000820:Animal Diseases / Q000517:prevention & control; D000818:Animals; D006691:Classical Swine Fever / Q000517:prevention & control; D003090:Coliphages; D007753:Laboratories; D011312:Pressure; D012934:Social Isolation; D013552:Swine
D000336:Aerosols