Intracellular localization of mevalonate-activating enzymes in plant cells.
Mevalonate-activating enzymes are shown to be present in the chloroplasts of French-bean leaves. The chloroplast membrane is impermeable to mevalonic acid. Mevalonate-activating enzymes also appear to be found outside the chloroplast. These results support the view that terpenoid biosynthesis in the plant cell is controlled by a combination of enzyme segregation and specific membrane permeability.
D001345:Autoradiography; D002736:Chloroplasts / Q000201:enzymology*; D002854:Chromatography, Paper; D066298:In Vitro Techniques; D008798:Mevalonic Acid / Q000378:metabolism; D010539:Permeability; D010770:Phosphotransferases / Q000378:metabolism*; D010945:Plants, Edible / Q000166:cytology / Q000201:enzymology*; D013729:Terpenes / Q000096:biosynthesis
D013729:Terpenes; D010770:Phosphotransferases; D008798:Mevalonic Acid