Characterization of trisubstituted cholanoic acids in human feces.
The trisubstituted cholanoic acids in human feces have been studied by gas chromatography-mass spectrometry. The following bile acids have been identified: 3 Beta,7alpha,12alpha-trihydroxy-, 3 Beta,7 Beta,12alpha-trihydroxy-, 3alpha,7alpha-dihydroxy-12-keto-5 Beta-cholanoic acids and 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholanoic acid. The presence in human feces of 3alpha,7alpha,12alpha-trihydroxy-, 3alpha,7,12alpha-trihydroxy-, and 3alpha,12alpha-dihydroxy-7-keto-5 Beta-cholanoic acids has been confirmed. The composition of bile acids in human feces is summarized and possible metabolic interrelationships suggested.
D001647:Bile Acids and Salts / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D005243:Feces / Q000032:analysis; D005463:Fluoroacetates / Q000032:analysis; D006801:Humans; D066298:In Vitro Techniques; D013057:Spectrum Analysis
D001647:Bile Acids and Salts; D005463:Fluoroacetates