Anticholinesterase-induced amnesia and its temporal aspects.
Injection of the anticholinesterase drug diisopropyl fluorophosphate into the hippocampi of rats, 30 minutes after escape learning, produces partial amnesia with full recovery 5 days after injection. No such amnesia is produced if the injection takes place 3 days after learning. However, with injections 5 days after learning there is again an effect, and at 14 days amnesia is complete though no normal forgetting occurs within this period.
D000647:Amnesia / Q000209:etiology*; D000818:Animals; D001522:Behavior, Animal; D006624:Hippocampus; D006801:Humans; D007531:Isoflurophate / Q000494:pharmacology*; D008297:Male; D011603:Psychophysiology; D051381:Rats
D007531:Isoflurophate