Actinomycin D inhibition of the zinc-induced formation of cytochrome c in Ustilago.
As reported earlier by Grimm & Allen, the addition of zinc to the sporidia of the smut fungus, Ustilago sphaerogena, evokes the formation of large amounts of cytochrome c. This occurs under conditions where the rates of increase of dry weight, RNA, and DNA remain unaffected. Actinomycin D added with zinc specifically abolishes the formation of cytochrome c. The system behaves as if cytochrome c were formed de novo.
D003580:Cytochromes / Q000096:biosynthesis*; D003609:Dactinomycin / Q000494:pharmacology*; D005658:Fungi; D015032:Zinc / Q000494:pharmacology*
D003580:Cytochromes; D003609:Dactinomycin; D015032:Zinc