Inhibition of drug metabolism. I. Kinetics of the inhibition of the N-demethylation of ethylmorphine by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and related compounds.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D004798:Enzymes / Q000494:pharmacology*; D005954:Glucosephosphate Dehydrogenase; D066298:In Vitro Techniques; D007521:Isocitrate Dehydrogenase; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D008861:Microsomes / Q000187:drug effects* / Q000201:enzymology*; D009020:Morphine; D011335:Proadifen / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats
D004798:Enzymes; D009020:Morphine; D011335:Proadifen; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase