N-Amidino-3,5-diamino-6-chloropyrazine-carboxamide: an active diuretic in the carboxamide series.
D000315:Adrenalectomy; D000450:Aldosterone / Q000494:pharmacology; D000577:Amides / Q000494:pharmacology*; D000578:Amidines / Q000494:pharmacology*; D000818:Animals; D003900:Desoxycorticosterone / Q000494:pharmacology*; D004232:Diuretics / Q000494:pharmacology*; D006852:Hydrochlorothiazide / Q000494:pharmacology; D006854:Hydrocortisone / Q000494:pharmacology; D008297:Male; D011188:Potassium / Q000032:analysis; D011719:Pyrazines / Q000494:pharmacology*; D051381:Rats; D012964:Sodium / Q000032:analysis; D013148:Spironolactone / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000378:metabolism*
D000577:Amides; D000578:Amidines; D004232:Diuretics; D011719:Pyrazines; D013438:Sulfhydryl Compounds; D006852:Hydrochlorothiazide; D013148:Spironolactone; D003900:Desoxycorticosterone; D000450:Aldosterone; D012964:Sodium; D011188:Potassium; D006854:Hydrocortisone