The treatment of pyogenic bone and joint infections by closed irrigation (circulation) with a non-toxic detergent and one or more antibiotics.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001847:Bone Diseases / Q000628:therapy*; D003902:Detergents / Q000494:pharmacology / Q000627:therapeutic use*; D004357:Drug Synergism; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000628:therapy*; D008875:Middle Aged; D010405:Penicillinase; D010477:Perfusion; D019736:Prostheses and Implants; D013501:Surface-Active Agents / Q000627:therapeutic use; D007507:Therapeutic Irrigation; D014945:Wound Healing; D014946:Wound Infection / Q000150:complications*
D000900:Anti-Bacterial Agents; D003902:Detergents; D013501:Surface-Active Agents; D010405:Penicillinase