The inhibition of induced motor activity in transplanted fundic pouches.
1. An increase in motor activity of transplanted fundic pouches can be produced repeatedly by an alkaline buffer solution in the duodenum.2. The response can be abolished by small doses of a cholecystokinin-pancreozymin extract.3. The secretagogues, olive oil and peptone will inhibit the response when introduced into the duodenum.4. Acetylcholine in the duodenum will also inhibit the effect.5. Hydrochloric acid will inhibit the motor activity produced by alkaline buffer in the duodenum and also resting activity of the pouches.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002766:Cholecystokinin / Q000494:pharmacology*; D004285:Dogs; D004386:Duodenum / Q000187:drug effects*; D006851:Hydrochloric Acid / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects*; D009821:Oils / Q000494:pharmacology; D010461:Peptones / Q000494:pharmacology; D013270:Stomach / Q000187:drug effects* / Q000502:physiology* / Q000637:transplantation
D009821:Oils; D010461:Peptones; D002766:Cholecystokinin; D000109:Acetylcholine; D006851:Hydrochloric Acid