Inhibition of lipolytic action of growth hormone and glucocorticoid by ultraviolet and x-radiation.
Addition of catecholamines or growth hormone plus glucocorticoid activates lipolysis in isolated white-fat cells of the rat. If the fat cells were irradiated just before the addition of growth hormone and glucocorticoid, their lipolytic action was abolished. However, irradiation did not affect the activation of lipolysis by catecholamines.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology*; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism; D050356:Lipid Metabolism; D009638:Norepinephrine / Q000494:pharmacology*; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis; D011830:Radiation Effects; D051381:Rats; D014316:Tritium; D014466:Ultraviolet Rays; D014529:Uridine / Q000378:metabolism
D014316:Tritium; D012313:RNA; D003907:Dexamethasone; D013006:Growth Hormone; D007930:Leucine; D014529:Uridine; D009638:Norepinephrine