The time course of the effect of thyroid hormones upon basal oxygen consumption and plasma concentration of free fatty acid in rats.
1. Basal O(2) consumption and plasma free fatty acid (FFA) concentration were measured in normal and hypothyroid rats at various intervals after the initiation of a course of treatment with thyroid hormones.2. A significant rise in basal O(2) consumption was detectable in both groups of rats before there was any change in plasma FFA level.3. It is concluded that the stimulatory effect of thyroid hormones on the basal O(2) consumption of the whole animal is not mediated entirely by a rise in plasma FFA level.
D000818:Animals; D005227:Fatty Acids / Q000097:blood*; D007037:Hypothyroidism; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D013961:Thyroid Gland / Q000502:physiology*; D013963:Thyroid Hormones / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology; D014284:Triiodothyronine / Q000494:pharmacology
D005227:Fatty Acids; D013963:Thyroid Hormones; D014284:Triiodothyronine; D013974:Thyroxine