Quantitative bacteriological analysis of sputum as a test of antibiotic efficacy.
After 5 days of treatment, sputa were analyzed from 40 patients treated with sodium fusidate and 20 patients treated with naficillin. There was a significant decrease in the number of staphylococci, but no significant change in the other flora. The quantitative bacteriological analysis of sputum specimens proved to be a useful laboratory procedure for providing information on the in vivo effectiveness of specific antibacterial therapy in respiratory infections.
D001419:Bacteria / Q000302:isolation & purification; D005672:Fusidic Acid / Q000627:therapeutic use*; D006801:Humans; D009254:Nafcillin / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use*; D013183:Sputum / Q000382:microbiology*; D013210:Staphylococcus / Q000302:isolation & purification; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D010406:Penicillins; D009254:Nafcillin; D005672:Fusidic Acid