Enzyme induction by corticosteroids in embryonic cells: steroid structure and inductive effect.
Glutamine synthetase in the developing retina of the chick embryo can be induced to increase by certain corticosteroids. The inductive effectiveness of various natural corticosteroids has been examined in organ cultures of embryonic retina and correlated with specific groupings on the steroid molecules.
D015065:17-Hydroxycorticosteroids / Q000494:pharmacology; D000450:Aldosterone / Q000494:pharmacology*; D000463:Algestone Acetophenide / Q000494:pharmacology; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002642:Chick Embryo; D002784:Cholesterol / Q000494:pharmacology; D003345:Corticosterone / Q000494:pharmacology*; D046508:Culture Techniques; D003900:Desoxycorticosterone / Q000494:pharmacology; D004790:Enzyme Induction; D005973:Glutamine; D006854:Hydrocortisone / Q000494:pharmacology*; D006908:Hydroxyprogesterones / Q000494:pharmacology*; D008025:Ligases / Q000096:biosynthesis*; D011284:Pregnenolone / Q000494:pharmacology; D011374:Progesterone / Q000494:pharmacology; D011372:Progestins / Q000494:pharmacology*; D012160:Retina / Q000196:embryology / Q000201:enzymology*
D015065:17-Hydroxycorticosteroids; D006908:Hydroxyprogesterones; D011372:Progestins; D005973:Glutamine; D003900:Desoxycorticosterone; D000450:Aldosterone; D011374:Progesterone; D011284:Pregnenolone; D002784:Cholesterol; D008025:Ligases; D000463:Algestone Acetophenide; D003345:Corticosterone; D006854:Hydrocortisone