Serum lipoproteins during chemical carcinogenesis.
1. The serum-protein and -lipoprotein patterns of rats, given a purified diet containing 0%, 0.005% or 0.03% 2-acetamidofluorene, have been determined by disk electrophoresis. 2. An abnormal high-density lipoprotein was detected from the first week of the experiment in the serum of the animals given the carcinogen. The low-density lipoproteins also increased on prolonged feeding with the carcinogen.
D000818:Animals; D001797:Blood Protein Electrophoresis; D002273:Carcinogens / Q000494:pharmacology*; D004032:Diet; D004428:Ear Neoplasms; D005449:Fluorenes / Q000494:pharmacology*; D008074:Lipoproteins / Q000097:blood*; D008113:Liver Neoplasms; D008297:Male; D008325:Mammary Neoplasms, Experimental; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D051381:Rats; D014461:Ultracentrifugation
D002273:Carcinogens; D005449:Fluorenes; D008074:Lipoproteins