Pigmentary changes of the skin associated with internal disease.
D000052:Acanthosis Nigricans / Q000150:complications; D000474:Alkaptonuria / Q000150:complications; D006432:Hemochromatosis / Q000150:complications; D006801:Humans; D010383:Pellagra / Q000150:complications; D010661:Phenylketonurias / Q000150:complications; D010859:Pigmentation Disorders / Q000209:etiology*