Cytotoxic effect of lymphocyte-antigen interaction in delayed hypersensitivity.
Lymph node cells from inbred rats having delayed sensitivity to soluble proteins inhibit growth of syngeneic or allogeneic fibroblasts in the presence of specific antigen. A relation is suggested between this in vitro phenomenon and other systems believed to be specific manifestations of delayed hypersensitivity.
D000818:Animals; D000941:Antigens; D046508:Culture Techniques; D005347:Fibroblasts / Q000187:drug effects*; D006968:Hypersensitivity, Delayed; D008198:Lymph Nodes / Q000166:cytology; D008214:Lymphocytes; D008297:Male; D010047:Ovalbumin; D051381:Rats; D014373:Tuberculin
D000941:Antigens; D014373:Tuberculin; D010047:Ovalbumin