Transforming activity of green monkey SA7(C8) adenovirus in tissue culture.
Simian SA7 (C8) adenovirus can effect transformation of mouse, rat, and hamster cells in tissue culture. The transforming activity of the virus was more pronounced in culture medium containing 0.1 millimolar CaCl(2), a lower concentration than that usually used. The transformed hamster cells were tumorigenic in hamsters.
D000256:Adenoviridae / Q000254:growth & development*; D000818:Animals; D006224:Cricetinae; D046508:Culture Techniques; D006801:Humans; D051379:Mice; D009858:Oncogenic Viruses / Q000254:growth & development*; D051381:Rats; D014170:Transformation, Genetic; D014776:Virus Cultivation