Antagonism of the conversion of alpha-methyldopa to an active symphathomimetic by 3-hydroxy-4-bromobenzyloxyamine (NSD 1055) and 3-hydroxybenzyloxyamine (NSD 1024).
D000814:Aniline Compounds / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology; D008750:Methyldopa / Q000037:antagonists & inhibitors*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D013566:Sympathomimetics / Q000096:biosynthesis*; D014439:Tyramine / Q000494:pharmacology
D000814:Aniline Compounds; D013566:Sympathomimetics; D008750:Methyldopa; D004295:Dihydroxyphenylalanine; D006899:Mixed Function Oxygenases; D004298:Dopamine; D009638:Norepinephrine; D014439:Tyramine