The conversion of noncarcinogenic aromatic amides to carcinogenic arylhydroxamic acids by synthetic N-hydroxylation.
D000230:Adenocarcinoma; D000577:Amides / Q000378:metabolism; D000818:Animals; D001646:Bile / Q000032:analysis; D002247:Carbon Isotopes; D002273:Carcinogens / Q000138:chemical synthesis*; D002855:Chromatography, Thin Layer; D005260:Female; D005449:Fluorenes; D006877:Hydroxamic Acids / Q000032:analysis / Q000138:chemical synthesis* / Q000652:urine; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D010534:Peritoneal Neoplasms / Q000139:chemically induced; D051381:Rats; D012509:Sarcoma
D000577:Amides; D002247:Carbon Isotopes; D002273:Carcinogens; D005449:Fluorenes; D006877:Hydroxamic Acids