Regional myocardial blood flow.
A method is described which measures the local effectiveness of the myocardial circulation, expressed as a clearance constant. Uniform clearance constants have been demonstrated in the normal canine and human myocardium. A distinct difference in clearance constants has been demonstrated between the normal canine myocardium and areas of naturally occurring disease. Heterogeneous clearance constants have been found in a majority of human subjects with coronary artery disease-the lowest rates being noted in areas of fibrous aneurysm.
D000783:Aneurysm / Q000503:physiopathology; D000818:Animals; D001775:Blood Circulation; D003327:Coronary Disease / Q000503:physiopathology; D003331:Coronary Vessels / Q000502:physiology* / Q000503:physiopathology; D004285:Dogs; D006801:Humans; D007726:Krypton; D011868:Radioisotopes; D012039:Regional Blood Flow / Q000502:physiology*
D011868:Radioisotopes; D007726:Krypton