The effect of glucose on cellobiose uptake and beta-D-glucosidase activity in Streptomyces granaticolor.
Glucose inhibits the inducible synthesis of beta-D-glucosidase in Streptomyces granaticolor. Neither cAMP nor cGMP influence the inhibitory effect of glucose. Glucose also inhibits the inducible synthesis of the cellobiose uptake system but has no effect on its activity. This may be the mechanism underlying glucose inhibition of induction of beta-D-glucosidase in S. granaticolor.
D001692:Biological Transport / Q000187:drug effects; D002475:Cellobiose / Q000378:metabolism*; D000242:Cyclic AMP / Q000494:pharmacology; D004187:Disaccharides / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology*; D005959:Glucosidases / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism*; D001617:beta-Glucosidase / Q000096:biosynthesis / Q000378:metabolism*
D004187:Disaccharides; D002475:Cellobiose; D000242:Cyclic AMP; D005959:Glucosidases; D001617:beta-Glucosidase; D005947:Glucose