T-lymphocytes subpopulations in peripheral blood of hepatocellular carcinoma patients.
Using commercially available monoclonal antibodies, we can classify the subpopulations of T-lymphocytes into OKT4+ cells (inducer/helper) and OKT8+ cells (cytotoxic/suppressor). Total of 32 histologically confirmed hepatocellular carcinoma (HCC) patients and 32 normal healthy individuals compatible in age and sex were included in this study. The result indicated that decline of OKT4+ cells, increase of OKT8+ cells and decrease of OKT4+ cells/OKT8+ cells ratio were observed in HCC patients as compared with normal control group.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000276:immunology; D006528:Carcinoma, Hepatocellular / Q000276:immunology*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008113:Liver Neoplasms / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000145:classification*
D000911:Antibodies, Monoclonal