[Changes in the structural characteristics and ATPase activity of the erythrocyte membranes in angiographically verified coronary artery lesion].
Structural characteristics and Na, K-ATPase activity of erythrocyte membranes were studied by the spin probe method in patients with an angiographically verified damage to the coronary arteries. The rise of the cholesterol/phospholipid ratio in patients with coronary heart disease was associated with the increased orderliness of the fatty acid chains of erythrocyte membrane lipids, leading to inhibition of Na, K-ATPase activity. The data point to the same line of changes in erythrocyte membranes and smooth muscle cells during the development of coronary heart disease.
D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging; D004578:Electron Spin Resonance Spectroscopy; D004910:Erythrocyte Membrane / Q000201:enzymology / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008560:Membrane Fluidity; D010743:Phospholipids / Q000097:blood; D011859:Radiography; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*; D013113:Spin Labels
D010743:Phospholipids; D013113:Spin Labels; D002784:Cholesterol; D000254:Sodium-Potassium-Exchanging ATPase
Izmeneniia strukturnykh kharakteristik i aktivnosti ATFazy v membranakh éritrotsitov pri angiograficheski podtverzhdennom porazhenii koronarnykh arteriĭ.