Impact of a single neonatal gonadotropin (FSH + LH) or thyrotropin (TSH) treatment on the sexual behaviour of the adult male rat.
A single gonadotropin (FSH + LH) treatment of neonatal male rats resulted in depression of sexual activity in adulthood. It appears that not only steroids, but also gonadotropins may alter adult sexual behaviour by a single neonatal exposure. The chemically related hormone thyrotropin (TSH) had a similar, but much less pronounced, effect on adult sexual activity.
D000818:Animals; D000831:Animals, Newborn; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000494:pharmacology*; D007031:Hypothalamus / Q000187:drug effects; D007986:Luteinizing Hormone / Q000494:pharmacology; D008297:Male; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013972:Thyrotropin / Q000494:pharmacology*
D006065:Gonadotropins, Pituitary; D011956:Receptors, Cell Surface; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin