Technetium-99m-labeled red blood cell imaging.
Red blood cells labeled with 99mTc constitute a suitable intravascular agent for imaging of vascular abnormalities. Hemangiomas are characterized by low perfusion and a high blood pool. This "perfusion blood-pool mismatch," not encountered in other lesions, may help in the specific diagnosis of this tumor. This is particularly so in cavernous hemangiomas of the liver where three-phase 99mTc-labeled red blood cell scintigraphy should precede liver biopsy. Red cell scintigraphy also is useful for establishing the vascular nature of hemangiomas of the head and neck and the skin and for diagnosis of venous occlusion. Heat-damaged red blood cells provide a specific spleen imaging agent. This should be used when patients with suspected splenic pathology have equivocal colloid scintigraphy.
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging; D002648:Child; D004912:Erythrocytes; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006392:Hemangioma, Cavernous / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000000981:diagnostic imaging*; D013154:Spleen / Q000002:abnormalities; D013159:Splenic Infarction / Q000000981:diagnostic imaging; D013667:Technetium; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000000981:diagnostic imaging
D013667:Technetium