Basal cell adenoma with parallel tubules in stromal cells of the parotid gland.
A case of basal cell adenoma in the right parotid region of a 51 years old male was reported. The tumor measured 2.5 cm x 3 cm, was spherical and covered with a fibrous capsule. Histologically, it was a tubular monomorphic adenoma with scant edematous interstitial tissue. The stromal cells stained positively by the PAP method using anti-S-100 protein serum. Electron microscopically, the tumor cells forming tubular had many microvilli at the luminal surface, many filaments in the cytoplasm and well developed desmosomes in the intercellular junctions. Ordinary intracellular organelles of the tumor cells were small in number, and their nuclei were oval with shallow indentation. In the dilated rough endoplasmic reticulum of the stromal cells, many straight parallel tubules were found. The tubules measured from 15 nm to 25 nm thick and 3.5 micrometers long in the longitudinal sections and from 25 nm to 30 nm in diameter with electron lucent core and poor coat in the cross sections. Other cell organelles of the stromal cells were small in number, and filaments and dense attachments were found in the ectoplasm. Around the stromal cells there was a discontinuous basement membrane.
D000236:Adenoma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D003094:Collagen / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D009418:S100 Proteins / Q000032:analysis; D013194:Staining and Labeling
D009418:S100 Proteins; D005169:Factor VIII; D003094:Collagen