title: Fertilization increases the polyphosphoinositide content of sea urchin eggs.
abstract: Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D003594:Cytoplasmic Granules / Q000502:physiology; D005089:Exocytosis; D005306:Fertilization; D008563:Membrane Lipids / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism*; D012617:Sea Urchins / Q000196:embryology*
chemical_list: D008563:Membrane Lipids; D010716:Phosphatidylinositols; D002118:Calcium