Studies on mechanism of entry of EB virus into non-B lymphocytes. Establishment of an EB virus-producing human-tupaia hybrid cell line TuH18.
With the use of the EB virus-producing lymphoblastoid cell line H18, an attempt was made to infect the monolayer cell culture of nasopharyngeal tissue from the normal tupaia, and an EB virus-producing, human-tupaia hybrid cell line was established. The mechanism of entry of EB virus into cells other than B lymphocytes is discussed in this paper.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002871:Chromosome Banding; D005814:Genes, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D006822:Hybrid Cells / Q000382:microbiology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000382:microbiology*; D009305:Nasopharynx / Q000382:microbiology; D014417:Tupaia
D000956:Antigens, Viral