The intrauterine diagnosis of hemoglobin disorders.
This article presents an overview of the use of fetal blood and DNA for prenatal testing. The molecular organization of the human hemoglobin genes, the structure of human hemoglobins, and the molecular defects of hemoglobinopathies are also discussed.
D000653:Amniotic Fluid / Q000032:analysis / Q000166:cytology; D000755:Anemia, Sickle Cell / Q000235:genetics; D002353:Carrier State; D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis; D004262:DNA Restriction Enzymes; D005260:Female; D005312:Fetal Blood / Q000032:analysis / Q000378:metabolism; D005817:Genetic Counseling; D006451:Hemoglobin, Sickle / Q000235:genetics; D006453:Hemoglobinopathies / Q000175:diagnosis*; D006454:Hemoglobins / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000235:genetics; D006801:Humans; D008722:Methods; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013789:Thalassemia / Q000175:diagnosis / Q000235:genetics
D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D006455:Hemoglobins, Abnormal; D004247:DNA; D004262:DNA Restriction Enzymes