25-Hydroxyvitamin D concentrations in maternal and cord blood at delivery and in maternal blood during lactation in Finland.
The 25-hydroxyvitamin D concentration (25-OHD) in maternal and cord blood of 192 mothers was determined at delivery from June to the end of November. Ninety-nine mothers had received a daily supplementation of 12.5 micrograms of vitamin D during pregnancy and this group had a significantly higher 25-OHD concentration both in maternal and in cord blood than in the corresponding non-supplemented group. A daily supplement of 2.5 micrograms of vitamin D was given to 63 of the mothers during lactation. Of these mothers 44 were still lactating after 6 months. The dietary vitamin D intake of 31 mothers was calculated. We found a significant correlation between the maternal serum 25-OHD concentration 16-18 weeks after delivery and the total vitamin D intake. The intake (5.5 micrograms/d, including supplementation) was lower than that recommended for lactating mothers which is 10 micrograms/d (Food and Nutrition Board, 1980).
D000293:Adolescent; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D002112:Calcifediol / Q000097:blood*; D002118:Calcium / Q000097:blood; D002762:Cholecalciferol / Q000008:administration & dosage; D005247:Feeding Behavior; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005387:Finland; D006801:Humans; D007231:Infant, Newborn; D007774:Lactation; D008431:Maternal-Fetal Exchange; D009751:Nutritional Requirements; D011247:Pregnancy; D012621:Seasons; D014808:Vitamin D Deficiency / Q000097:blood
D002762:Cholecalciferol; D000469:Alkaline Phosphatase; D002112:Calcifediol; D002118:Calcium