[Immunochemical analysis of oligosaccharide fragments of O-specific Shigella flexneri polysaccharides].
Comparison of inhibitory properties of several synthetic oligosaccharides related to Sh. flexneri O-specific polysaccharides, namely Glc alpha 1-3Rha alpha 1-OMe, Glc alpha 1-3Rha alpha 1-2Rha alpha 1-OMe, Rha alpha 1-2(Glc alpha 1-3)Rha alpha 1-OMe, GlcNAc beta 1-2(Glc alpha 1-3)Rha alpha 1-OMe, and GlcNAc beta 1-2(Glc alpha 1-3) Rha alpha 1-2Rha alpha 1-OMe, using passive haemagglutination reaction demonstrated the tetrasaccharide to possess the highest activity in V; 7,8-anti-7,8 immune system. Among the oligosaccharides under study, only Rha alpha 1-2(Glc alpha 1-3)Rha alpha 1-OMe exhibited moderate anti-V activity.
D000942:Antigens, Bacterial / Q000032:analysis*; D000939:Epitopes / Q000032:analysis*; D007120:Immunochemistry; D019081:O Antigens; D009844:Oligosaccharides / Q000032:analysis*; D012763:Shigella flexneri / Q000276:immunology*
D000942:Antigens, Bacterial; D000939:Epitopes; D019081:O Antigens; D009844:Oligosaccharides
Immunokhimicheskiĭ analiz oligosakharidnykh fragmentov O-spetsificheskikh polisakharidov Shigella flexneri.