title: Restriction analysis and homology studies of the bovine adenovirus 7 genome.
abstract: We located the cleavage sites for restriction endonucleases EcoRI, HindIII, and BamHI on the genome of bovine adenovirus 7. Cross-hybridization at reduced stringency revealed two regions of homology shared by the DNA of human adenovirus 2 and bovine adenoviruses 7 and 3. These regions correspond to the hexon and the IVa2 protein genes of the human adenovirus. Another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide IIIa genes. These results allowed us to align the restriction map of bovine adenovirus 7 with respect to the other adenoviruses.
mesh_terms: D000256:Adenoviridae / Q000235:genetics*; D000260:Adenoviruses, Human / Q000235:genetics; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002478:Cells, Cultured; D004262:DNA Restriction Enzymes; D005814:Genes, Viral; D008297:Male; D009693:Nucleic Acid Hybridization; D013045:Species Specificity; D013737:Testis
chemical_list: D004262:DNA Restriction Enzymes