Maternal transmission of hepatocellular carcinoma.
A family in which four members have died of hepatocellular carcinoma is presented. Hepatitis B surface antigen was present in both cases in which it was sought and also present in nine of ten surviving siblings in the second generation. Maternal transmission of hepatitis B surface antigen and susceptibility to hepatocellular carcinoma is postulated.
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000235:genetics* / Q000276:immunology; D005260:Female; D005838:Genotype; D006506:Hepatitis A / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis / Q000235:genetics; D006801:Humans; D008113:Liver Neoplasms / Q000235:genetics* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D010375:Pedigree; D044465:White People
D006510:Hepatitis B Antibodies