Inhibition of glycosidases by aldonolactones of corresponding configuration. The C-4- and C-6-specificity of beta-glucosidase and beta-galactosidase.
1. In barley, beta-glucosidase and beta-galactosidase are separate enzymes. The former also displays beta-d-fucosidase activity. 2. In the limpet, Patella vulgata, beta-glucosidase activity is associated with the beta-d-fucosidase, previously shown to be a separate entity from the beta-galactosidase also present. 3. Almond emulsin presents all three activities as a single enzyme. Each is equally inhibited by glucono-, galactono- and d-fucono-lactone. 4. In rat epididymis, there is no significant beta-glucosidase activity, nor is there appreciable inhibition of the beta-galactosidase and beta-d-fucosidase activities of the preparation by gluconolactone.
D000818:Animals; D002523:Edible Grain / Q000201:enzymology; D004822:Epididymis / Q000201:enzymology; D005696:Galactosidases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005959:Glucosidases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006027:Glycosides / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007783:Lactones / Q000378:metabolism*; D008297:Male; D008974:Mollusca
D006027:Glycosides; D007783:Lactones; D005696:Galactosidases; D005959:Glucosidases