[Immunity indices of mice immunized with different vaccines against Japanese encephalitis].
The test of adoptive transfer of immunity demonstrated that in the mice vaccinated with inactivated Japanese encephalitis vaccines the protective activity to the homologous virus is provided predominantly by B-lymphocytes the protective effect of which is enhanced by cooperative interaction with T-lymphocytes. The culture (CV) and purified brain (BV) vaccines induce high levels of humoral and cell-mediated immunity, however, the capacity of CV to produce antibody is higher than that of BV. Both preparations do not cause in vaccinated mice any changes in responsiveness to extraneous antigen (sheep red cells), or disorders in chemotaxic mobility of leukocytes and phagocytic activity of macrophages.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002464:Cell Migration Inhibition; D002634:Chemotaxis, Leukocyte; D004664:Encephalitis Virus, Japanese / Q000276:immunology*; D004672:Encephalitis, Japanese / Q000276:immunology* / Q000517:prevention & control; D007114:Immunization / Q000379:methods; D007116:Immunization, Passive; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D051379:Mice; D010587:Phagocytosis; D013154:Spleen / Q000276:immunology; D013997:Time Factors; D014765:Viral Vaccines / Q000008:administration & dosage*
D000914:Antibodies, Viral; D014765:Viral Vaccines
Pokazateli immuniteta u mysheĭ, immunizirovannykh razlichnymi vaktsinami protiv iaponskogo éntsefalita.