title: Studies on 1-methyl adenine transfer RNA methyltransferase of Mycobacterium smegmatis.
abstract: The presence of 1-methyl adenine in transfer RNA is a feature that Mycobacterium smegmatis shares with only a few other prokaryotes. The enzyme 1-methyl adenine tRNA methyl transferase from this source has been purified and the preliminary results show the presence of two activity peaks with different substrate specificity.
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives / Q000378:metabolism; D002474:Cell-Free System; D002848:Chromatography, DEAE-Cellulose; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli; D008745:Methylation; D009161:Mycobacterium / Q000201:enzymology*; D012329:RNA, Bacterial / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism; D013379:Substrate Specificity; D012359:tRNA Methyltransferases / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D012329:RNA, Bacterial; C008407:1-methyladenine; D012343:RNA, Transfer; D012359:tRNA Methyltransferases; C023194:tRNA (adenine(58)-N(1))-methyltransferase; D000225:Adenine