title: [Aphasia caused by left paramedian thalamic infarction. Anatomo-clinical case].
abstract: A 67 year-old right-handed man presented with an aphasia of acute onset associated to paralysis of vertical eye movements, mild cerebellar right dysmetria and right hemiparesis without hemianopia. CT scan showed two low density areas in the left thalamus and left occipital lobe. Neuropsychological examination revealed a non fluent aphasia with normal repetition, semantic paraphasias, perseverations and good comprehension of verbal and written commands. There was no alexia. Writing was impaired only by motor disturbances. Three weeks after the onset, tetraparesis and impairment of consciousness followed by a locked in syndrome supervened. Death occurred four months after onset. Neuropathological examination showed a left paramedian thalamic infarct involving the ventrolateral, dorso-medial and intralaminar nuclei, sparing the pulvinar. There was an occipital infarct sparing the calcarine scissura and multiple infarctions in the pons and the cerebellum. Broca's and Wernicke's areas were spared. We suggest that the involvement of medial nuclei could be partly responsible of language disturbances in thalamic aphasia.
mesh_terms: D000368:Aged; D001037:Aphasia / Q000209:etiology* / Q000473:pathology; D001921:Brain / Q000473:pathology*; D002544:Cerebral Infarction / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D013786:Thalamic Diseases / Q000150:complications* / Q000473:pathology
vernacular_title: Aphasie par infarctus thalamique paramédian gauche. Observation anatomo-clinique.