title: [Cerebral metastasis of choriocarcinoma].
abstract: One hundred and eighty-two cases of choriocarcinoma were treated in our clinic during the 26 years period from 1957 to 1982. Forty-one patients among them (2.3%) had cerebral metastases. Analysis on the autopsy findings of patients with cerebral metastases of choriocarcinoma proved neurosurgical resectability in most cases. Craniotomy and removal of cerebral metastatic lesion has been adopted since 1972, and a significant difference was noted in the surviving time between surgically treated group and the group without surgery. The risk factors for developing brain metastases were analyzed. Patients whose uterine lesion showed immature type of histopathology (p less than 0.01), patients without uterine lesion (p less than 0.05) and patients with pulmonary metastasis (p less than 0.01) had higher risk of developing cerebral metastasis.
mesh_terms: D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000008:administration & dosage; D001921:Brain / Q000601:surgery; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D002822:Choriocarcinoma / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011379:Prognosis; D011879:Radiotherapy Dosage; D014594:Uterine Neoplasms / Q000473:pathology
chemical_list: D001500:BCG Vaccine; D003609:Dactinomycin; D003520:Cyclophosphamide; D000324:Adrenocorticotropic Hormone