title: Inhibition by actinomycin D of uridine diphosphoglucose synthetase activity during differentiation of Dictyostelium discoideum.
abstract: Actinomycin D inhibits the increase in specific activity of uridine diphosphoglucose synthetase during differentiation of the cellular slime mold, Dictyostelium discoideum. The degree to which this inhibition occurs is strictly correlated with, and may result from, the general inhibition of morphogenesis by actinomycin D.
mesh_terms: D002454:Cell Differentiation / Q000187:drug effects; D003609:Dactinomycin / Q000494:pharmacology*; D008025:Ligases / Q000378:metabolism*; D009235:Myxomycetes / Q000187:drug effects* / Q000201:enzymology* / Q000254:growth & development
chemical_list: D003609:Dactinomycin; D008025:Ligases