A new device and method for rapid processing of cytologic smears, histologic sections and cell cultures for electron microscopy.
A device and technique are described by means of which samples may be selectively lifted from flat surfaces, such as microscope slides or coverslips, and processed for examination with the electron microscope. The device consists of a spring clamp that holds the narrow end of an open-tipped, conical B.E.E.M. or similar capsule sealed against the surface from which the sample of interest is to be removed. All processing of the sample for electron microscopy can take place within the capsule. When completed, the capsule filled with solidified resin is removed with the area of interest of the sample embedded in its tip.
D006528:Carcinoma, Hepatocellular / Q000648:ultrastructure; D003584:Cytological Techniques / Q000295:instrumentation; D006801:Humans; D008113:Liver Neoplasms / Q000648:ultrastructure; D008168:Lung / Q000648:ultrastructure; D008854:Microscopy, Electron