Influence of GABA on the spectral and spatial coding of goldfish retinal ganglion cells.
The responses of center red ON and center red OFF ganglion cells of the isolated goldfish retina to a flickering stimulus light diminish by GABA. Without stimulation GABA blocks the maintained activity of the OFF cells. With a green flickering spot in the receptive field center, the green ON-response of the OFF cells becomes an OFF-response during GABA administration. It is concluded that, besides the common antagonistic green input, the receptive field center of these cells also has a synergistic green input, which is mediated by a pathway other than the center opponent red and green inputs.
D000818:Animals; D003118:Color Perception / Q000187:drug effects*; D046508:Culture Techniques; D005074:Evoked Potentials, Visual / Q000187:drug effects; D006054:Goldfish; D010775:Photic Stimulation; D010852:Picrotoxin / Q000494:pharmacology; D012160:Retina / Q000187:drug effects*; D012165:Retinal Ganglion Cells / Q000187:drug effects*; D013028:Space Perception / Q000187:drug effects*; D009435:Synaptic Transmission / Q000187:drug effects*; D014794:Visual Fields / Q000187:drug effects; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D010852:Picrotoxin; D005680:gamma-Aminobutyric Acid