title: [Antibody reaction to basic myelin proteins after intracisternal administration into animals].
abstract: Pathogenetic properties of antibodies to main protein of myelin, which are responsible for initiation of demyelinization process in the central nervous system, are discussed. Development of the process is accompanied by alteration in a number of biochemical reactions. Effects of the antibodies to main protein of myelin, after their intracisternal administration, are considered in relation to activation of proteolysis, alteration of glycolipid content and the functional state of the brain.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D000917:Antibody Formation; D001609:Beta-Globulins / Q000032:analysis* / Q000134:cerebrospinal fluid; D001921:Brain / Q000276:immunology*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D009103:Multiple Sclerosis / Q000276:immunology; D004676:Myelin Basic Protein / Q000276:immunology*; D013569:Synapses / Q000276:immunology
chemical_list: D000906:Antibodies; D001609:Beta-Globulins; D004676:Myelin Basic Protein
vernacular_title: Deĭstvie antitel k osnovnomu belku mielina pri intratsisternal'nom vvedenii ikh zhivotnym.