Transmission of hepatitis A by transfusion of blood products.
The transmission of hepatitis A by blood products has been thought to occur rarely or not at all. By measuring IgM antibody to hepatitis A virus, we diagnosed a case of hepatitis A transmitted by the transfusion of a unit of fresh frozen plasma. Since the commercial availability of methods for measuring IgM antibody to hepatitis A, four other well-defined cases of hepatitis A transmitted by blood products have been reported in the literature. We detail our case and the natural history and importance of this clinical entity.
D000328:Adult; D000914:Antibodies, Viral / Q000276:immunology*; D001782:Blood Donors; D001793:Blood Preservation; D002648:Child; D005260:Female; D005615:Freezing; D006506:Hepatitis A / Q000276:immunology / Q000635:transmission*; D035922:Hepatitis A Antibodies; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010949:Plasma; D065227:Transfusion Reaction
D000914:Antibodies, Viral; D035922:Hepatitis A Antibodies