title: Preload and afterload reduction in treating congestive heart failure.
abstract: The importance of changes in the resistance and capacitance vessels in the development of congestive heart failure was demonstrated over 30 years ago. The beneficial effects of reducing total peripheral resistance and increasing vascular capacitance were also demonstrated. These studies illustrate the old adage "there is nothing new under the sun."
mesh_terms: D001340:Autonomic Nerve Block; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics; D018738:Hexamethonium; D006584:Hexamethonium Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000503:physiopathology; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D006584:Hexamethonium Compounds; D018738:Hexamethonium