title: Occurrence of a transposition from the X-chromosome long arm to the Y-chromosome short arm during human evolution.
abstract: DXYS1, a site showing greater than 99% DNA sequence homology between the human X and Y chromosomes, maps to the X long arm and to the Y short arm. In great apes, sequences homologous to DXYS1 are found only on the X chromosome. These findings suggest an X-Y transposition during human evolution.
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D004303:Dosage Compensation, Genetic; D005260:Female; D008297:Male; D011323:Primates / Q000235:genetics*; D014178:Translocation, Genetic; D014960:X Chromosome / Q000648:ultrastructure*; D014998:Y Chromosome / Q000648:ultrastructure*
chemical_list: D004262:DNA Restriction Enzymes