title: 1H and 31P nuclear magnetic resonance spectroscopy of erythrocyte extracts in myotonic muscular dystrophy.
abstract: Extracts freshly prepared from erythrocytes of patients with myotonic muscular dystrophy, their unaffected siblings, and normal control subjects were examined with both 1H and 31P nuclear magnetic resonance spectroscopy. A moderate variability was found in the relative amounts of various nonphosphorylated compounds among patients and control subjects; however, no significant differences were found between the groups. As for the phosphorylated compounds, the sum of ADP + ATP was found significantly elevated in the myotonic muscular dystrophy patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D006801:Humans; D006859:Hydrogen; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000097:blood / Q000175:diagnosis*; D010472:Perchlorates / Q000097:blood; D010710:Phosphates / Q000097:blood; D010758:Phosphorus
chemical_list: D010472:Perchlorates; D010710:Phosphates; D010758:Phosphorus; D006859:Hydrogen