Possible mechanism of inhibition by lipid peroxidation of ATPase activities of rat cerebral cortex synaptosomes.
The effects of metal ions and drugs which inhibit ATPase activities of synaptosomes have been determined on the lipid peroxidation activity of synaptosomes. Whilst some metal ions and drugs appear to influence the ATPase activities through a mechanism involving lipid peroxidation, others affect the enzymes directly or by other mechanisms.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D002540:Cerebral Cortex / Q000201:enzymology*; D066298:In Vitro Techniques; D008054:Lipid Peroxides / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000494:pharmacology; D008670:Metals / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013574:Synaptosomes / Q000187:drug effects / Q000201:enzymology*
D008054:Lipid Peroxides; D008670:Metals; D008315:Malondialdehyde; D000251:Adenosine Triphosphatases; D000254:Sodium-Potassium-Exchanging ATPase