Fibronectin in eosinophilic globules of Spitz's nevi.
Nine cases of Spitz's nevi, compound type, that had large homogeneous eosinophilic globules at the dermo-epidermal junction were stained with anti-fibronectin antibodies by the biotin-avidin indirect immunofluorescence technique. Fibronectin was demonstrated in all nine cases. This study demonstrates that fibronectin, which is present in the extracellular matrix material, is also localized in a homogeneous pattern in the eosinophilic globules of the Spitz's nevi.
D005353:Fibronectins / Q000032:analysis*; D006801:Humans; D009508:Nevus, Pigmented / Q000032:analysis*; D012867:Skin / Q000032:analysis; D012878:Skin Neoplasms / Q000032:analysis*; D013194:Staining and Labeling
D005353:Fibronectins