[Induction of immunosuppression by dietary aversion acquired in the absence of immunosuppressive treatment].
Conditioned taste aversion induced by either an immunosuppressive (cyclophosphamide) or non immunosuppressive (lithium chloride) drug reduced expression of a T cell mediated immune response that is highly susceptible to stress hormones. These results demonstrate that the proposed concept of conditioned immunosuppression really represents another example of how stress can alter normal regulation of cell mediated immune events.
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D002712:Chlorides / Q000494:pharmacology; D003213:Conditioning, Psychological / Q000502:physiology*; D003520:Cyclophosphamide / Q000494:pharmacology; D005260:Female; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008094:Lithium / Q000494:pharmacology; D018021:Lithium Chloride; D051379:Mice; D008807:Mice, Inbred BALB C; D013649:Taste
D002712:Chlorides; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008094:Lithium; D018021:Lithium Chloride
Induction d'une immunosuppression par une aversion alimentaire acquise en l'absence de traitement immunosuppreseur.