The chemiluminescence of rabbit alveolar macrophages induced by quartz dust particles.
Quartz dust particles (respirable fraction) triggered luminol-dependent chemiluminescence (CL) when added to unstimulated rabbit alveolar macrophages (AM). It was shown by increasing the dust dose added to the same amount of cells, and conversely, that the intensity of chemiluminescent reaction depended on the ratio cells:dust particles. The ratio giving maximum CL yield was estimated.
D000818:Animals; D004391:Dust; D066298:In Vitro Techniques; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology; D008264:Macrophages / Q000502:physiology*; D011650:Pulmonary Alveoli / Q000502:physiology*; D011791:Quartz / Q000494:pharmacology*; D011817:Rabbits; D012822:Silicon Dioxide / Q000494:pharmacology*
D004391:Dust; D011791:Quartz; D008165:Luminol; D012822:Silicon Dioxide