[Immunochemical characteristics of artificial antigens with Salmonella O-determinants 4 and 9].
Two new synthetic high-molecular protein-free O-antigens have been obtained. These O-antigens are copolymers of synthetic disaccharides with acrylamide. The copolymers of alpha-allylglycosides, abequosyl-(alpha 1----3]-mannopyranose and tyvelosyl-(alpha 1----3)-mannopyranose, with acrylamide have been shown to possess, respectively, the specificity of immunodominant O-factors 4 and 9 characteristic of Salmonella serogroups B and D1. The synthetic O-antigens have proved to possess higher capacity for binding antibodies in the precipitation test and the hemagglutination inhibition test than the corresponding lipopolysaccharides.
D000178:Acrylamides / Q000032:analysis* / Q000138:chemical synthesis / Q000276:immunology; D000818:Animals; D000941:Antigens / Q000032:analysis* / Q000276:immunology; D000942:Antigens, Bacterial / Q000032:analysis* / Q000276:immunology; D004187:Disaccharides / Q000032:analysis* / Q000138:chemical synthesis / Q000276:immunology; D000939:Epitopes / Q000032:analysis* / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D007106:Immune Sera / Q000302:isolation & purification; D007114:Immunization / Q000379:methods; D005779:Immunodiffusion; D008070:Lipopolysaccharides / Q000276:immunology; D019081:O Antigens; D011817:Rabbits; D012475:Salmonella / Q000276:immunology*; D012485:Salmonella typhi / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D012995:Solubility
D000178:Acrylamides; D000941:Antigens; D000942:Antigens, Bacterial; D004187:Disaccharides; D000939:Epitopes; D007106:Immune Sera; D008070:Lipopolysaccharides; D019081:O Antigens
Immunokhimicheskaia kharakteristika iskusstvennykh antigenov s O-determinantami 4 i 9 Salmonella.