[The mitochondrial carrier of adenylates controls ATP production in the physiological range of respiration rates].
The problem is considered concerning the amount of control exerted by different mitochondrial enzymes on oxidative phosphorylation. Using the data of Groen et al. (1982) it has been found that when the respiration rates for isolated mitochondria ranged from 30 to 50 per cent of that in state 3 (which is in apparent physiological range) the contribution of the adenine nucleotide translocator to the control of ATP production was no less than 90 per cent taking for 100 per cent the total contribution of all mitochondrial enzymes.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism; D003576:Electron Transport Complex IV / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism*; D008954:Models, Biological; D010085:Oxidative Phosphorylation; D051381:Rats
D000227:Adenine Nucleotides; D002352:Carrier Proteins; D000255:Adenosine Triphosphate; D003576:Electron Transport Complex IV; D006593:Hexokinase
Mitokhondrial'nyĭ perenoschik adenilatov osushchestvliaet reguliatsiiu proizvodstva ATF v fiziologicheskom diapazone skorosteĭ dykhaniia.