[A monoclonal antibody reactive with scirrhous carcinoma of the stomach].
A monoclonal antibody reactive with human gastric carcinoma was established. When formalin-fixed, paraffin-embedded histological sections were stained by avidin-biotin-peroxidase complex method using this monoclonal antibody, it was found to react with 89% (17/19) of the scirrhous carcinomas (diffuse type of carcinoma) and 72% (13/18) of the differentiated adenocarcinomas of the stomach tested. However, this antibody did not react with normal gastric mucosa or various other normal tissues except the mucosa of the large intestine.
D002293:Adenocarcinoma, Scirrhous / Q000276:immunology* / Q000473:pathology; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology; D015295:Antigens, Tumor-Associated, Carbohydrate; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D013274:Stomach Neoplasms / Q000276:immunology* / Q000473:pathology
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate