[Malignant testicular tumor treated with cytostatic drugs in a case of kidney transplantation for familial cystic kidney].
The case is presented of a 29-year-old male who developed embryonal testicular carcinoma two months after successful transplantation of a cadaver kidney because of end stage renal disease due to polycystic disease. After surgical removal of the carcinoma and 3 courses of chemotherapy with bleomycin and vinblastine, complete remission was induced which has now lasted for 14 months. In addition to the usual toxicity of cytotoxic therapy, transplant function decreased intermittently but renal function recovered under close monitoring and dose-adaptation of immunosuppressive medication with cyclosporin and prednisolone.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications / Q000235:genetics* / Q000601:surgery; D013724:Teratoma / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000150:complications / Q000188:drug therapy*; D014747:Vinblastine / Q000008:administration & dosage
D001761:Bleomycin; D014747:Vinblastine
Zytostatisch behandelter maligner Hodentumor bei Nierentransplantation wegen familiärer Zystennieren.