[Energy transformation in mitochondria: the role of the iron-sulfur center N-2 of NADH-dehydrogenase].
The data on the action of the iron-sulfur centre N-2 in the 1 site of respiration and oxidative phosphorylation coupling obtained by the authors as well as by other investigators are reviewed in terms of conformational - relaxation concept of energy transformation. The study of the direct and reverse electron transport bears testimony to the fact that the N-2 centre with its proper protein surrounding plays the role of the protein transformer of energy in the 1 site.
D000494:Allosteric Regulation; D000818:Animals; D001665:Binding Sites; D003579:Cytochrome Reductases / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D004579:Electron Transport; D004734:Energy Metabolism; D007506:Iron-Sulfur Proteins / Q000378:metabolism*; D008667:Metalloproteins / Q000378:metabolism*; D008928:Mitochondria / Q000201:enzymology* / Q000378:metabolism; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism; D009245:NADH Dehydrogenase / Q000378:metabolism*; D010084:Oxidation-Reduction; D011487:Protein Conformation; D051381:Rats
D007506:Iron-Sulfur Proteins; D008667:Metalloproteins; D003579:Cytochrome Reductases; D009245:NADH Dehydrogenase
Transformatsiia énergii v mitokhondriiakh: rol' zhelezosernogo tsentra N-2 NADH-degidrogenazy.