Preclinical evaluation of acid products for treatment of solid experimental skin tumors in mice.
The effect of nitric acid preparations on five different solid experimental tumors in mice was studied. None of these highly malignant tumors was eradicated by any of the acid preparations studied, although differences in reactivity were noted between preparations in some models.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D004353:Drug Evaluation, Preclinical; D005260:Female; D051379:Mice; D008819:Mice, Nude; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy; D009566:Nitrates / Q000627:therapeutic use*; D017942:Nitric Acid; D012509:Sarcoma / Q000139:chemically induced / Q000188:drug therapy; D012878:Skin Neoplasms / Q000139:chemically induced / Q000188:drug therapy*; D013601:T-Lymphocytes
D009566:Nitrates; D017942:Nitric Acid; D015127:9,10-Dimethyl-1,2-benzanthracene