Transmission of monkey retrovirus similar to human T-cell leukemia virus by blood transfusion.
Transfusion of 15 ml of blood from a rhesus monkey seropositive for human T-cell leukemia virus (HTLV) antigens to an anti-HTLV negative rhesus monkey resulted in the seroconversion of the recipient after five weeks. Cultured peripheral lymphocytes from the seroconverted monkey expressed HTLV antigens and type C virus particles.
D000818:Animals; D000917:Antibody Formation; D000956:Antigens, Viral / Q000032:analysis*; D001803:Blood Transfusion; D017977:Deltaretrovirus / Q000276:immunology*; D005260:Female; D007181:Inclusion Bodies, Viral / Q000032:analysis; D008214:Lymphocytes / Q000382:microbiology; D008251:Macaca / Q000382:microbiology*; D008253:Macaca mulatta / Q000382:microbiology*; D008297:Male
D000956:Antigens, Viral