Effects of mercury on acetylcholinesterase (E.C. 3.1.1.7.) activity of erythrocytes and bone marrow in rats.
The studies were carried out on male Wistar rats, where the activity of acetylcholinesterase (AchE-E.C. 3.1.1.7) was determined in red cells and bone marrow under the influence of organic and anorganic mercury compounds. A marked decline in the activity of the enzyme could be noted, along with a more pronounced effect of the organic mercury compound on AchE.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000201:enzymology; D002800:Cholinesterase Inhibitors / Q000378:metabolism*; D004912:Erythrocytes / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D008627:Mercuric Chloride / Q000633:toxicity*; D010662:Phenylmercuric Acetate / Q000633:toxicity*; D010663:Phenylmercury Compounds / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D002800:Cholinesterase Inhibitors; D010663:Phenylmercury Compounds; D008627:Mercuric Chloride; D000110:Acetylcholinesterase; D010662:Phenylmercuric Acetate