[The proviral genome of murine radioleukosis virus: molecular cloning, restriction analysis and integration sites in the DNA of tumor cells].
An infectious clone of the linear, unintegrated RadLV provirus was obtained by insertion in the plasmid pBR322. Its restriction map was indistinguishable from that of the majority of the multiple proviral copies, which are found apparently at random sites in the DNA of RadLV-induced rat thymic lymphomas.
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D004273:DNA, Neoplasm / Q000235:genetics* / Q000302:isolation & purification; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D005814:Genes, Viral; D009052:Leukemia Virus, Murine / Q000235:genetics*; D007953:Leukemia, Radiation-Induced / Q000235:genetics / Q000382:microbiology*; D051379:Mice; D008815:Mice, Inbred Strains; D013953:Thymus Neoplasms / Q000235:genetics / Q000382:microbiology*
D004273:DNA, Neoplasm; D004279:DNA, Viral; D004262:DNA Restriction Enzymes
Le génome proviral du virus des radioleucoses murines (RadLV): clonage moléculaire, analyse de restriction et sites d'intégration dans l'ADN des cellules tumorales.