title: Aflatoxins in human breast milk.
abstract: Breast milk from 99 Sudanese mothers was analysed for aflatoxins. Aflatoxins M1 and/or M2 were detected in 37 of the milks. No other aflatoxin was detected. M1 occurred alone in 13 milks, (mean 19.0 pg/ml), M2 in 11 milks (mean 12.2 pg/ml), and in 13 samples both M1 and M2 were detected. There appeared to be a linear relationship between M1 and M2 where both were excreted. No aflatoxin was detected in subcutaneous abdominal wall fat removed during Caesarian section from 15 women, but was present in three out of 14 bloods taken during anaesthesia. The presence of aflatoxins in mothers' milk showed no correlation with duration of lactation, the infants' nutrition, presence of aflatoxin in mothers' blood, or the infant's blood and urine. It is concluded that some Sudanese women excrete aflatoxins in breast-milk at levels similar to or higher than those considered safe in animal milk, for human consumption.
mesh_terms: D000273:Adipose Tissue / Q000032:analysis; D016607:Aflatoxin M1; D000348:Aflatoxins / Q000032:analysis* / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D007223:Infant; D007774:Lactation; D008895:Milk, Human / Q000032:analysis*; D011247:Pregnancy; D013997:Time Factors
chemical_list: D000348:Aflatoxins; D016607:Aflatoxin M1; C030379:aflatoxin M2