Cefotaxime-associated diarrhea and Clostridium difficile.
A patient with rheumatoid arthritis-associated interstitial pneumonitis, treated with prednisolone, developed mild colitis due to Clostridium difficile in association with the use of cefotaxime (CTX). Diarrhea was successfully treated with the discontinuation of CTX and initiation of oral vancomycin.
D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy; D002439:Cefotaxime / Q000009:adverse effects*; D003015:Clostridium Infections / Q000188:drug therapy / Q000209:etiology*; D003092:Colitis / Q000188:drug therapy / Q000209:etiology*; D003967:Diarrhea / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000188:drug therapy; D014640:Vancomycin / Q000627:therapeutic use
D014640:Vancomycin; D011239:Prednisolone; D002439:Cefotaxime