[Effector cell adrenoreceptors--local regulators of the intensity of the adrenergic reaction].
An activation of adrenoreceptors initiates both the specific adrenergic response and the process aiming at its limitation. Catecholamines induce a desensitization of adrenoreceptors acting as competitive autoinhibiting agents on the adrenergic response. A mechanism of feedback transsynaptic regulation becomes involved which inhibits accumulation of noradrenaline in the adrenergic neuron. A deficit of adrenergic effect activates the above steps of adrenergic process.
D000818:Animals; D002395:Catecholamines / Q000494:pharmacology / Q000502:physiology; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D005246:Feedback; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology / Q000502:physiology; D011817:Rabbits; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology*; D017981:Receptors, Neurotransmitter / Q000187:drug effects / Q000502:physiology; D013997:Time Factors
D002395:Catecholamines; D011941:Receptors, Adrenergic; D017981:Receptors, Neurotransmitter; D009638:Norepinephrine
Adrenoretseptory éffektornoĭ kletki--lokal'nye reguliatory intensivnosti adrenergicheskoĭ reaktsii.