title: Pyruvate carboxylase. X. The demonstration of direct coordination of pyruvate and alpha-ketobutyrate by the bound manganese and the formation of enzyme-metal-substrate bridge complexes.
mesh_terms: D000818:Animals; D002384:Catalysis; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002645:Chickens; D007651:Keto Acids / Q000032:analysis*; D007700:Kinetics; D008025:Ligases / Q000032:analysis*; D046911:Macromolecular Substances / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000032:analysis*; D008930:Mitochondria, Liver / Q000201:enzymology; D008956:Models, Chemical; D008961:Models, Structural; D011485:Protein Binding; D011773:Pyruvates / Q000032:analysis*; D013696:Temperature; D013816:Thermodynamics
chemical_list: D007651:Keto Acids; D046911:Macromolecular Substances; D011773:Pyruvates; D008345:Manganese; D008025:Ligases