title: Cytochemical localisation of 5'-nucleotidase in amoeboid microglial cells in postnatal rats.
abstract: The activity of the enzyme 5'-nucleotidase has been studied in postnatal rats. In 5 days old rats, under the light microscope, round amoeboid microglial cells were stained for the enzyme. The cytoplasm was stained dark brown, with a clear nucleus. In older rats, the reactive amoeboid microglial cells assumed an oval or flattened form. In the electron microscope, in 5 days old rat, reaction product was deposited at various sites in the cytoplasm of the amoeboid microglial cells: over lysosomes in subplasmalemmal vacuoles as well as in saccules of the Golgi apparatus. In older rats the cells showed reaction over the lysosomes. The cells became oval and elongated.
mesh_terms: D015720:5'-Nucleotidase; D000818:Animals; D000831:Animals, Newborn; D003337:Corpus Callosum / Q000166:cytology; D006651:Histocytochemistry; D008854:Microscopy, Electron; D009457:Neuroglia / Q000201:enzymology* / Q000648:ultrastructure; D009708:Nucleotidases / Q000032:analysis*; D051381:Rats; D012688:Septum Pellucidum / Q000166:cytology
chemical_list: D009708:Nucleotidases; D015720:5'-Nucleotidase