Type I familial amyloidotic polyneuropathy (Japanese type).
Our recent studies on familial amyloidotic polyneuropathy (FAP) were reviewed. Since the clinical picture of our FAP is slightly different from those of the Portuguese type, the Swedish type, and the Jewish type, structural identification of the amyloid fibril proteins should be clarified on a molecular basis. Further investigation on the effectiveness of dimethyl sulfoxide (DMSO) or a search for other useful new drugs is greatly required.
D000328:Adult; D000682:Amyloid; D000686:Amyloidosis / Q000145:classification / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D055598:Chemical Phenomena; D002621:Chemistry; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000473:pathology; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology
D000682:Amyloid; D004121:Dimethyl Sulfoxide