Estimation of mutation rates induced by large doses of gamma, proton and neutron irradiation of the X-chromosome of the nematode Panagrellus redivivus.
The radiation-resistant free-living nematode Panagrellus redivivus was used to study mutation rates in oocytes, following gamma, proton and neutron irradiation in the dose range 45-225 grays. gamma-Radiation produced approximately 0.001 lethal X-chromosomes per gray over the range tested. Proton or neutron irradiation produced approximately 0.003 lethal X-chromosomes per gray at lower doses, with the mutation rate dropping to 0.001 lethal X-chromosome per gray at the higher doses. These results suggest a dose-dependent mutation-repair system. Cell lethality was also examined. gamma-Radiation produced the greatest amount of cell lethality at all doses, while neutron irradiation had no cell lethal effect at any of the doses examined.
D000818:Animals; D003433:Crosses, Genetic; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D005804:Genes, Lethal / Q000528:radiation effects; D005808:Genes, Recessive / Q000528:radiation effects; D008297:Male; D009154:Mutation; D009348:Nematoda / Q000235:genetics / Q000528:radiation effects*; D009502:Neutrons; D011522:Protons; D012098:Reproduction / Q000528:radiation effects; D014960:X Chromosome / Q000528:radiation effects*
D011522:Protons