[Protective effectiveness of the blood sera and immune system cells from mice immunized with live or inactivated influenza virus].
The results of the study of comparative protective role of humoral and cell-mediated immunity factors obtained from inbred donor mice immunized with live or inactivated influenza virus are presented. The superiority of the live virus over the inactivated preparation as the inducer of not only humoral but especially cell-mediated immune response was demonstrated by the effectiveness of passive intranasal protection of the infected mice, by the degree of inhibition of virus reproduction in the lungs of the protected mice, and by the capacity for interferon production by the cells of the immune system of donor mice.
D000818:Animals; D007106:Immune Sera / Q000276:immunology*; D007116:Immunization, Passive; D009980:Influenza A virus / Q000276:immunology / Q000502:physiology; D007252:Influenza Vaccines / Q000276:immunology*; D007372:Interferons / Q000096:biosynthesis; D007739:L Cells / Q000276:immunology; D008168:Lung / Q000382:microbiology; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000517:prevention & control; D013601:T-Lymphocytes / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000276:immunology; D014779:Virus Replication
D007106:Immune Sera; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated; D007372:Interferons
Zashchitnaia éffektivnost' syvorotok krovi i kletok immunnoĭ sistemy mysheĭ, immunizirovannykh zhivym ili inaktivirovannym virusom grippa.