Two oral beta-adrenergic stimulant drugs, pirbuterol and salbutamol, in reversible airway obstruction.
Pirbuterol and salbutamol capsules were compared in a multi-centre, double-blind, crossover study. Pirbuterol 10 mg four times daily and salbutamol 4 mg four times daily produced a similar increase in peak expiratory flow rate, matched by the patients' subjective appreciation of decreased beathlessness. Both drugs produced the same incidence of tremor.
D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000402:Airway Obstruction / Q000188:drug therapy* / Q000503:physiopathology; D000420:Albuterol / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004983:Ethanolamines / Q000627:therapeutic use*; D005541:Forced Expiratory Volume; D006801:Humans; D010366:Peak Expiratory Flow Rate
D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D004983:Ethanolamines; C009118:pirbuterol; D000420:Albuterol