Varicella infection in a children's hospital: prevention by vaccine and an episode of airborne transmission.
Varicella vaccine was used safely and effectively for preventing ward infection with varicella. Ward infection was experienced 34 times in 5 years between 1977 and 1982. During these ward infections, varicella developed in 4 of 142 patients who received vaccine, 21 of 47 patients who did not receive vaccine and 1 of 9 who received transfusion with vaccine-boostered blood. Of the 142 vaccinated patients, the four in whom varicella developed showed symptoms 3 to 10 days after vaccination, indicating that vaccination had been too late. Details of a ward infection with varicella by airborne transmission and its prevention by vaccination are presented.
D000391:Air Microbiology; D002644:Chickenpox / Q000517:prevention & control* / Q000635:transmission; D002648:Child; D003428:Cross Infection / Q000517:prevention & control* / Q000635:transmission; D005260:Female; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006776:Hospitals, Pediatric; D006782:Hospitals, Special; D006801:Humans; D007116:Immunization, Passive; D007564:Japan; D014611:Vaccination; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines