[Platelet aggregation and antihypertensive alpha-adrenergic agonists].
In their experimental researches the Authors showed that the well-known antihypertensive alpha-adrenergic stimulant drugs (clonidine, flutonidine and guanabenz) were able to antagonize at very high concentrations the platelet aggregation induced by ADP and by thrombin on rabbit PRP.
D000244:Adenosine Diphosphate / Q000037:antagonists & inhibitors; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D003000:Clonidine / Q000494:pharmacology*; D006143:Guanabenz / Q000494:pharmacology*; D006146:Guanidines / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D013917:Thrombin / Q000037:antagonists & inhibitors; D014052:Toluidines / Q000494:pharmacology
D000316:Adrenergic alpha-Agonists; D006146:Guanidines; D007093:Imidazoles; D014052:Toluidines; D000244:Adenosine Diphosphate; D013917:Thrombin; D006143:Guanabenz; D003000:Clonidine; C010227:flutonidine
Aggregazione delle piastrine ed anti-ipertensivi alpha-adrenergici stimolanti.