3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane.
D015121:6-Ketoprostaglandin F1 alpha; D000818:Animals; D011464:Epoprostenol / Q000378:metabolism*; D066298:In Vitro Techniques; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D008780:Methyltransferases / Q000037:antagonists & inhibitors; D011453:Prostaglandins / Q000378:metabolism*; D011460:Prostaglandins F / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344; D013929:Thromboxane B2 / Q000378:metabolism*; D013931:Thromboxanes / Q000378:metabolism*; D014372:Tubercidin / Q000494:pharmacology
D008070:Lipopolysaccharides; D011453:Prostaglandins; D011460:Prostaglandins F; D013931:Thromboxanes; C018258:3-deazaadenosine; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D011464:Epoprostenol; D008780:Methyltransferases; D014372:Tubercidin