title: A growing clinical problem: plasmid-determined resistance to aminocyclitol-aminoglycosides in enterobacteria.
abstract: The contents of this paper include the following items: Incidence of R+ gentamicin-resistant enterobacteria and gentamicin usage. Aminocyclitol-modifying enzymes produced by 719 R+ isolates of enterobacteria belonging to different genera. Epidemiology of some plasmids (so-called pUZ) determining resistance to aminocyclitol in enterobacteria. Comparison of AAC (3) classes.
mesh_terms: D000123:Acetyltransferases / Q000032:analysis; D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000201:enzymology; D005839:Gentamicins / Q000494:pharmacology; D009713:Nucleotidyltransferases / Q000032:analysis; D010770:Phosphotransferases / Q000032:analysis; D011815:R Factors
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005839:Gentamicins; D000123:Acetyltransferases; D010770:Phosphotransferases; D009713:Nucleotidyltransferases; C020658:glutamine-synthetase adenylyltransferase