title: [Effectiveness of sympathoadrenergic blocking in prevention of postoperative acute pancreatitis].
abstract: The role of the vascular factor (namely hypoperfusion) in the onset of pancreatic necrosis is a well-established fact. In the present study an analysis is made of the efficiency of drug blocking of alpha and beta adreno-receptors in the prophylaxis of acute postoperative pancreatitis, following surgery of the Oddi sphincter. Compared with a control group of 301 papillo-sphincterotomies performed in a previous period the application of adrenergic blocking in 127 patients in whom interventions were performed on the Oddi sphincter led to a significant reduction in both morbidity and mortality through acute postoperative pancreatitis, from 5 to 2,3%, and from 1,3 to 0,7% respectively.
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D001660:Biliary Tract Diseases / Q000601:surgery; D005767:Gastrointestinal Diseases / Q000601:surgery; D006801:Humans; D010195:Pancreatitis / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D009803:Sphincter of Oddi / Q000601:surgery
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists
vernacular_title: Eficienţa blocajului simpatoadrenergic în profilaxia pancreatitei acute postoperatorii.