Selective chromosomal damage caused by human cytomegalovirus.
The effect of human cytomegalovirus (CMV) on human foetal cell chromosomes was investigated. Cultures of foetal skin fibroblasts were infected with human CMV (AD-169 strain) and their chromosomes analysed at intervals. The distribution of chromosomal abnormalities was independent of chromosome length.
D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D003587:Cytomegalovirus / Q000502:physiology*; D005347:Fibroblasts; D006801:Humans