title: Stimulation of amniotic fluid cell growth by cartilage growth factor.
abstract: Cartilage growth factor (CGF) stimulates the growth of primary and secondary cultures of human amniotic fluid cells. Over a 14--16-day period there is an approximately 70% enhancement in the number of cells in primary cultures and a 170% increase in secondary cultures. Neither the karyotype or the specific activities of lysosomal enzymes are altered by the presence of CGF in the medium.
mesh_terms: D000653:Amniotic Fluid / Q000166:cytology*; D000818:Animals; D002417:Cattle; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D002553:Cerebroside-Sulfatase / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D005260:Female; D006133:Growth Substances / Q000494:pharmacology*; D006596:Hexosaminidases / Q000032:analysis; D006801:Humans; D007621:Karyotyping; D008247:Lysosomes / Q000201:enzymology; D011247:Pregnancy; D011506:Proteins / Q000494:pharmacology*; D001616:beta-Galactosidase / Q000032:analysis
chemical_list: D006133:Growth Substances; D011506:Proteins; D002553:Cerebroside-Sulfatase; D006596:Hexosaminidases; D001616:beta-Galactosidase