Pre- and postoperative use of lormetazepam.
In preoperative use, the administration of 2 mg of lormetazepam perorally to patients no doubt abnormally nervous in anticipation of a forthcoming operation has proved to be an excellent inducer of sound sleep. In postoperative use, a dose of 2 mg of lormetazepam has a positive effect compared with the placebo, both on sleep inducement and on quality and duration of sleep. However, the results of a small series of twelve patients indicate that for recently operated adults the administration of 3 mg of lormetazepam may be recommended. Indeed we believe 4 mg might not be excessive.
D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001569:Benzodiazepines; D001842:Bone and Bones / Q000601:surgery; D004311:Double-Blind Method; D004325:Dreams / Q000187:drug effects; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000031:analogs & derivatives / Q000627:therapeutic use*; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care; D012890:Sleep / Q000187:drug effects*; D012893:Sleep Wake Disorders / Q000517:prevention & control
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; C023842:lormetazepam; D008140:Lorazepam