Bradykinin and the dextran anaphylactoid reaction in rats.
A comparison was made of the activities of clinical dextran and bradykinin in rats. Chiefly by using antagonists, major differences were identified and the study confirmed that bradykinin is unlikely to play a major role in the dextran anaphylactoid reaction.
D000707:Anaphylaxis / Q000209:etiology*; D000818:Animals; D001920:Bradykinin / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D003911:Dextrans / Q000037:antagonists & inhibitors / Q000633:toxicity*; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D008297:Male; D051381:Rats; D012702:Serotonin Antagonists / Q000494:pharmacology
D003911:Dextrans; D006634:Histamine H1 Antagonists; D012702:Serotonin Antagonists; D001920:Bradykinin