Identification of GABA receptor binding sites in rat and rabbit uterus.
The present study provides evidence for the presence of gamma-aminobutyric acid (GABA) and L-glutamate decarboxylase in the uteri of the rat and the rabbit. Furthermore, it has been demonstrated for the first time that the uterine tissue contains high-affinity GABAA receptor binding sites in a high density. The present findings indicate that GABA may have a role in the uterine functions.
D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D005260:Female; D005968:Glutamate Decarboxylase / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D011963:Receptors, GABA-A; D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase