Chickenpox vaccination of healthy children: immunological and clinical responses and protective effect in 1978-1982.
A total of 915 normal children without a history of varicella were immunized with a live varicella vaccine (Oka strain) between 1978 and 1982. As clinical reaction after vaccination, fever and or a slight rash was observed in only 10 children. A serological response was observed in all 524 children examined. Of the 854 children who could be followed, 602 children had contact with varicella patients, but extremely mild varicella with a rash developed in only 10 of them. Mild zoster occurred in one child who was admitted to hospital with mycoplasma pneumonia.
D001831:Body Temperature; D002644:Chickenpox / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007223:Infant; D014611:Vaccination / Q000009:adverse effects; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines