Suppression of intention tremor by contingent deep-brain stimulation.
Severe intention tremor of the upper limb was suppressed in three patients with multiple sclerosis by stimulation in the contralateral midbrain and basal ganglia with stereotactically placed bipolar electrodes. Permanent electrodes were implanted in two patients. The therapeutic effects of stimulation have in part been maintained, without any change in electrical threshold, throughout the period of observation (six months).
D000328:Adult; D001479:Basal Ganglia / Q000502:physiology; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D005260:Female; D006801:Humans; D008636:Mesencephalon / Q000502:physiology; D009103:Multiple Sclerosis / Q000628:therapy; D013997:Time Factors; D014202:Tremor / Q000628:therapy*