title: [Physiopathology and treatment of cardiac insufficiency in the acute stage of infarct].
abstract: Pump failure in acute myocardial infarction is a frequent complication in which the prognosis is still uncertain. The effects of ischemia and necrosis on ventricular performance are discussed, more specifically with reference to the role of some adaptive processes in exacerbating cardiac failure or lesion extension. The different therapeutic approaches considered have a dual purpose: to improve ventricular performance but without aggravating myocardial O2 balance. The hemodynamic response to a decrease in afterload and/or preload obtained by vasodilators is compared to the effects of beta-adrenergic agents. A therapeutic scheme is proposed.
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology*; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000318:Adrenergic beta-Agonists; D014665:Vasodilator Agents
vernacular_title: Physiopathologie et traitement de l'insuffisance cardiaque au stade aigu de l'infarctus.