title: Obesity and the development of the diffuse neuroendocrine system.
abstract: The diffuse neuroendocrine system may play a critical role in the events of both adaptation for impending famine and of arousal from the opioid-induced conservation state. This may occur by means of the opioid and anti-opioid peptides of APUD cells acting in conjunction with shifts in biogenic amine uptake and release.
mesh_terms: D001078:APUD Cells / Q000502:physiology*; D000222:Adaptation, Physiological; D000328:Adult; D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism; D004723:Endorphins; D004734:Energy Metabolism; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D006815:Hunger / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009490:Neurosecretory Systems / Q000254:growth & development / Q000502:physiology*; D009765:Obesity / Q000209:etiology* / Q000235:genetics
chemical_list: D001679:Biogenic Amines; D004723:Endorphins