title: [Effects of amyl nitrite on left ventricular systole times in normal subjects and those with aortic valvulopathy. Echophonomechanographic assessment].
abstract: Echophonomechanographic traces showing systole times, the circumferential restriction time, and the ejection fraction were compared in normal subjects, those with aortic stenosis, and those with aortic insufficiency under basal conditions and after 45" inhalation of amyl nitrite. Significant changes in these parameters after stimulation were noted in the normal subjects only, while the differences between the two groups of patients and the controls were also statistically significant under both experimental conditions. The fact that the diseased subjects did not reach the values noted in the controls is attributed to a latent contractility defect under basal conditions that is rendered evident by amyl nitrite. Stress is laid on the usefulness of the drug in the detection of left ventricle myocardial contraction defects via the analysis of ventricular function.
mesh_terms: D000328:Adult; D000680:Amyl Nitrite; D001022:Aortic Valve Insufficiency / Q000503:physiopathology*; D001024:Aortic Valve Stenosis / Q000503:physiopathology*; D004452:Echocardiography; D006352:Heart Ventricles / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects*; D013599:Systole / Q000187:drug effects*
chemical_list: D000680:Amyl Nitrite
vernacular_title: Effetti del nitrito d'amile sui tempi sistolici del ventricolo sinistro in soggetti normali e con valvulopatia aortica. Studio eco-fonomeccanocardiografico.