[Clinical trials of various glaucoma drugs acting on the adrenergic system (author's transl)].
The authors summarize findings in a clinical trial of the betablockers Timolol and Metoprolol, as well as the effectiveness of various concentration of the combination preparation Guanethidine-Adrenaline. In the trial Timolol proved to be the almost ideal drug for glaucoma therapy. However, as a pressure-lowering agent the guanethidine-epinephrine combination is more effective. Metroprolol, which is a pure beta 1-blocker, is probably preferable to Timolol in asthmatic patients.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004837:Epinephrine / Q000627:therapeutic use; D005901:Glaucoma / Q000188:drug therapy*; D006145:Guanethidine / Q000627:therapeutic use; D006801:Humans; D008790:Metoprolol / Q000627:therapeutic use; D013999:Timolol / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D004338:Drug Combinations; D013999:Timolol; D008790:Metoprolol; D004837:Epinephrine; D006145:Guanethidine
Klinische Prüfung verschiedener am adrenergen System angreifender Glaukom-Medikamente.