Diagnosis of Hodgkin's disease hampered by an Epstein-Barr virus infection treated with acyclovir.
We report a case of Hodgkin's disease associated with Epstein-Barr virus (EBV) infection in a 75-year-old male. The patient was given a 5-day course of acyclovir to which he responded well, with partial resolution of the lymphoma and return to well-being. A biopsy from the lymphoma after acyclovir treatment showed a change in the histological picture with a reduction in the number of giant cells. Relationships between EBV infection and Hodgkin's lymphoma are discussed.
D000212:Acyclovir / Q000627:therapeutic use*; D000368:Aged; D004854:Herpesvirus 4, Human; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000188:drug therapy; D008297:Male
D000212:Acyclovir