[Ceftriaxone as a single-dose treatment for male gonococcal urethritis].
Ceftriaxone was used in single intravenously dose of 1 g to treat 20 men with gonorrhoea caused by penicillinase-producing Neisseria gonorrhoeae (PPNG) and non-PPNG. Of 14 patients followed up, 13 (92.9%) were cured. Cure rates for PPNG infections and non-PPNG infections were 100% and 90.9% respectively. No side effect was observed except 1 case of vomiting out of 20 cases. It is concluded that this drug is safe and effective in treating both PPNG and non-PPNG infections.
D000328:Adult; D002439:Cefotaxime / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D002443:Ceftriaxone; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000302:isolation & purification; D014526:Urethritis / Q000188:drug therapy*
D002443:Ceftriaxone; D002439:Cefotaxime