[Damage to the Ca2+-transport system of cardiac sarcoplasmic reticulum during emotion-pain stress].
The influence of emotional-pain stress on the properties of the sarcoplasmic reticulum Ca2+-transporting system of the rat heart muscle was studied. The decrease of the Ca2+-dependent component of the Ca2+, Mg2+-ATPase activity, Ca2+-binding capacity and the rate of Ca2+-transport was found in the animals after stress. These alterations in the Ca2+-transporting system were caused by lipid peroxidation and could be prevented by the antioxidant ionol.
D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D010146:Pain / Q000378:metabolism; D051381:Rats; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D013312:Stress, Physiological / Q000378:metabolism*; D013315:Stress, Psychological / Q000378:metabolism
D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D002118:Calcium
Povrezhdenie Ca2+-transportiruiushcheĭ sistemy sarkoplazmaticheskogo retikuluma serdtsa pri émotsional'no-bolevom stresse.