title: Prazosin in general practice.
abstract: Forty-seven consecutive hypertensive patients, 27 of whom were inadequately controlled on previous therapy, were included in a general-practice study using prazosin hydrochloride as anti-hypertensive therapy. Eleven (23 percent) had their hypertension controlled by prazosin alone, increasing to 68 percent with the addition of a diuretic, and to 87 percent by adding a beta blocker with or without a diuretic. The range of dosage varied widely and the side effects, although frequent, were not serious. Prazosin is considered to be a useful anti-hypertensive agent especially in combination with thiazides and/or beta blockers.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011224:Prazosin / Q000008:administration & dosage / Q000627:therapeutic use*; D011799:Quinazolines / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D004232:Diuretics; D011799:Quinazolines; D011224:Prazosin