[Functional state of the sympathetic-adrenal system in melanocyte-stimulating hormone deficiency under the effect of the melanocyte-inhibiting factor of the hypothalamus].
Fluorometry was applied to the study of the content of a number of amines (DOPA), adrenalin, noradrenaline) in the adrenal glands and various structures of the rat brain in endogenous deficiency of melanocyte-stimulating hormone of the hypophysis caused by parenteral administration of synthetic melanostatin (MIF) of the hypothalamus. The amines content in the adrenal glands medulla, and also in the medulla oblongata; the cerebellum, and the large hemispheres proved to change 30 to 60 min after MIF administration. The results obtained indicated that various links of the sympathico-adrenal system could take part in the mechanism of MIF action on the hypophysis.
D000313:Adrenal Medulla / Q000378:metabolism*; D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D002531:Cerebellum / Q000378:metabolism; D003864:Depression, Chemical; D006728:Hormones / Q000494:pharmacology; D009075:MSH Release-Inhibiting Hormone / Q000494:pharmacology*; D008297:Male; D008526:Medulla Oblongata / Q000378:metabolism; D009074:Melanocyte-Stimulating Hormones / Q000037:antagonists & inhibitors / Q000172:deficiency*; D051381:Rats; D013564:Sympathetic Nervous System / Q000378:metabolism*
D002395:Catecholamines; D006728:Hormones; D009074:Melanocyte-Stimulating Hormones; D009075:MSH Release-Inhibiting Hormone
Funktsional'noe sostoianie simpatiko-adrenalovoĭ sistemy pri defitsite melanotsitstimuliruiushchego gormona gipofiza pod vliianiem melanotsitingibiruiushchego faktora gipotalamusa.