Interaction between Sendai virus and the cell membranae I. Restricted number of Sendai virus particles engaged in fusion with chicken red cell membrane.
The interaction between Sendai virus (HVJ) and the cell membrane was studied from a quantitative point of view, using artificially induced haemolytic virus particles and chicken red blood cells (CRBC). It was shown that one artificially induced haemolytic virus particle can lyse one erythrocyte. A method to accurately enumerate the actual number of virus particles fused to one CRBC was established. The number of virus particles adsorbed on to the CRBC increased with increasing multiplicities of infection (moi). The highest number of virus particles fused with one CRBC was 20 and was obtained from an inoculation of about 100 virus particles per CRBC (moi 100).
D000327:Adsorption; D000818:Animals; D002645:Chickens / Q000097:blood; D004910:Erythrocyte Membrane / Q000382:microbiology*; D004912:Erythrocytes / Q000276:immunology / Q000382:microbiology*; D005615:Freezing; D006461:Hemolysis; D010222:Parainfluenza Virus 1, Human / Q000254:growth & development* / Q000276:immunology