Expression of the 3' terminal region of human T-cell leukemia viruses.
Human T-cell leukemia viruses (HTLV) are closely associated with some human T-cell leukemias and lymphomas. A unique 3' region of the HTLV genome is believed to be involved in HTLV-induced cellular transformation, although the function of this region has yet to be determined. A subgenomic messenger RNA transcribed from this region of HTLV has now been characterized. These results provide direct evidence for the expression of a novel gene in HTLV.
D001483:Base Sequence; D002460:Cell Line; D002472:Cell Transformation, Viral; D017977:Deltaretrovirus / Q000235:genetics* / Q000502:physiology; D005814:Genes, Viral; D006801:Humans; D009693:Nucleic Acid Hybridization; D012326:RNA Splicing; D012333:RNA, Messenger / Q000235:genetics; D012367:RNA, Viral / Q000235:genetics*; D013601:T-Lymphocytes; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics*
D012333:RNA, Messenger; D012367:RNA, Viral; D014764:Viral Proteins