title: Mapping of trxB, a mutation responsible for reduced thioredoxin reductase activity.
abstract: The mutation (trxB) responsible for reduced thioredoxin reductase activity has been mapped on the Escherichia coli K-12 chromosome clockwise from aroA between 20 and 21 min. The gene order in this region of the E. coli chromosome was found to probably be serC-aroA-trxB. The location of gshA, the structural gene for gamma-glutamylcystein synthetase, relative to srl and recA also was determined.
mesh_terms: D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D003433:Crosses, Genetic; D004262:DNA Restriction Enzymes; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D008040:Genetic Linkage; D005838:Genotype; D009154:Mutation; D009247:NADH, NADPH Oxidoreductases / Q000235:genetics*; D010641:Phenotype; D013880:Thioredoxin-Disulfide Reductase / Q000235:genetics*; D014161:Transduction, Genetic
chemical_list: D009247:NADH, NADPH Oxidoreductases; D013880:Thioredoxin-Disulfide Reductase; D004262:DNA Restriction Enzymes