title: [Functional activity of the thymus gland and pituitary-adrenal system in patients with malignant skin melanoma].
abstract: Essential changes in the thymus functional condition and hypophyseal-adrenal system were revealed in patients with skin melanoma. The secretory activity of the thymus loosens, and there is a reduction of thymic hormone titer in blood. The increased levels of ACTH and hydrocortisone in blood indicate an enhanced activity of the hypophyseal-adrenal system under this pathology.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008545:Melanoma / Q000503:physiopathology*; D008875:Middle Aged; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D012878:Skin Neoplasms / Q000503:physiopathology*; D013935:Thymic Factor, Circulating / Q000032:analysis; D013950:Thymus Gland / Q000503:physiopathology*
chemical_list: D000324:Adrenocorticotropic Hormone; D013935:Thymic Factor, Circulating; D006854:Hydrocortisone
vernacular_title: Funktsional'naia aktivnost' vilochkovoĭ zhelezy i gipofizarno-nadpochechnikovoĭ sistemy u bol'nykh zlokachestvennoĭ melanomoĭ kozhi.