[Pymadine, a new type of non-depolarizing muscle-relaxant antagonist].
The paper presents the author's experience in post-anesthetic decurarization with a new antagonist of competitive curare. Presented for the first time in 1970, 4-amino-pyridine was found o tbe a substance with a different mode of action than that of reversible inhibitors of cholinesterase, without parasympaticomimetic effects, and without untoward effects on the cardio-circulatory function. It also has a central analeptic effect. This is why the authors consider the new drug as a powerful means for reversing the competitive neuromuscular blockage.
D015761:4-Aminopyridine; D000631:Aminopyridines / Q000008:administration & dosage*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D002800:Cholinesterase Inhibitors / Q000008:administration & dosage*; D003472:Curare / Q000037:antagonists & inhibitors; D006801:Humans; D009467:Neuromuscular Depolarizing Agents / Q000008:administration & dosage*; D011182:Postoperative Care
D000631:Aminopyridines; D000697:Central Nervous System Stimulants; D002800:Cholinesterase Inhibitors; D009467:Neuromuscular Depolarizing Agents; D003472:Curare; D015761:4-Aminopyridine
Pymadine, un nou tip de antagonist al miorelaxantelor nedepolarizante.