title: The iodine status of grazing sheep as monitored by concentrations of iodine in milk.
abstract: The iodine nutrition of grazing ewes was assessed from milk iodine concentrations. In 54 flocks sampled throughout Victoria, the mean milk iodine concentrations in ewes ranged from 79 to 1831 micrograms/l. In 2 flocks where newborn lambs had goitre the concentrations in ewes ranged from 45 to 98 micrograms/l. A marked seasonal variation was apparent when ewes in a flock were sampled at monthly intervals over 2 years. Milk iodine concentrations were highest at the end of summer, and were lowest in spring. In grazing ewes the milk iodine concentrations remained relatively constant throughout the day. In ewes given single oral doses of up to 2 mg iodine, milk iodine concentrations increased to maximum within 5 h, the increment being related to the dose administered, and decreased to pretreatment concentrations within 24 h. Milk iodine concentrations in ewes given 1 ml iodised oil intramuscularly remained significantly higher than untreated ewes in the same flock for 16 months after treatment. The effectiveness of the single injection was still apparent after 2 consecutive pregnancies in the ewes.
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D007455:Iodine / Q000032:analysis*; D007459:Iodized Oil / Q000494:pharmacology; D008892:Milk / Q000032:analysis*; D011193:Potassium Iodide / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D011891:Rain; D012621:Seasons; D012756:Sheep / Q000378:metabolism*; D012987:Soil / Q000032:analysis; D013696:Temperature
chemical_list: D012987:Soil; D011193:Potassium Iodide; D007459:Iodized Oil; D007455:Iodine