Hepatocellular carcinoma and cirrhosis: a review of their relative incidence in a 25-year period in the Florence area.
An eight-fold increase in the incidence of hepatocellular carcinoma in the Florence area was detected in a 25-year retrospective review of adult autopsy records in the Institute of Pathology of the University of Florence. During the same period, the incidence of cirrhosis did not show a parallel increase. The relationship between hepatocellular carcinoma, cirrhosis and HB virus is briefly discussed in the light of these findings.
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007558:Italy; D008103:Liver Cirrhosis / Q000453:epidemiology*; D008113:Liver Neoplasms / Q000453:epidemiology*; D008297:Male; D012189:Retrospective Studies; D013997:Time Factors