Effect of dyes on the photodecomposition of pyridoxine and pyridoxamine.
Erythrosine, eosine Y, rose bengal, mercurochrome, methylene blue, azure A and azure B accelerated the photodecomposition of pyridoxine and pyridoxamine at pH 5-9, but fluorescein and acid red did not. The photodecomposition of pyridoxine in the presence of erythrosine was greatest at pH 9.0. The singlet oxygen generated by light-excited dyes played a role as a mediator in the decomposition of pyridoxine and pyridoxamine in the presence of dyes was depressed by aminopyrine, sulpyrine and tryptophan. Pyridoxine 3,4'-dioctanoate was stable in the presence of erythrosine.
D004396:Coloring Agents / Q000494:pharmacology*; D010782:Photolysis; D011733:Pyridoxamine / Q000528:radiation effects*; D011736:Pyridoxine / Q000528:radiation effects*
D004396:Coloring Agents; D011733:Pyridoxamine; D011736:Pyridoxine