title: Serological evidence of infection with California serogroup viruses (family Bunyaviridae) in residents of Long Hua, suburb of Shanghai, People's Republic of China.
abstract: Sera from 126 residents of Long Hua, a suburb of Shanghai, in the People's Republic of China, were studied. Sera were tested for haemagglutination inhibiting antibodies to alphavirus (eastern equine encephalitis, western equine encephalitis), flavivirus (St. Louis encephalitis, Powassan, dengue) and California serogroup (snowshoe hare) antigens. Flavivirus antibodies were found in 14 (11.1%) and California serogroup antibodies in 5 (3.9%) individuals. Neutralizing antibodies with highest titres to snowshoe hare virus were demonstrated in 3 of the 5 California serogroup reactors. We believe this to be the first report of California serogroup virus antibodies in Chinese residents and the first evidence to suggest that California serogroup viruses may be circulating in the Orient.
mesh_terms: D000293:Adolescent; D000328:Adult; D000524:Alphavirus / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis*; D002043:Bunyaviridae / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D002681:China; D002141:Encephalitis Virus, California / Q000276:immunology*; D004671:Encephalitis, Arbovirus / Q000453:epidemiology*; D004670:Encephalitis, California / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D005416:Flavivirus / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests
chemical_list: D000956:Antigens, Viral