[Transient reduced adrenal gland function following large vascular surgical interventions].
In 48 patients with aorto-femoral bypass-operations pre- and postoperative measurements of total serumcorticoids were performed. All serum levels were then compared to a control group undergoing large abdominal operations. In contrast to the control group twelve patients with aorto-femoral bypass-operations showed values that were for a time clearly below preoperative levels. In six patients with bypass-operations values could be found which were for a short time within the limits of relative adrenal insufficiency. ACTH-stimulation test performed in these patients showed significant lower values than those preoperatively measured. Due to systemic overdose heparinization we believe haemorrhage within the adrenal glands to be responsible for these changes.
D000302:Adrenal Cortex / Q000098:blood supply; D000305:Adrenal Cortex Hormones / Q000097:blood*; D000309:Adrenal Insufficiency / Q000097:blood*; D000324:Adrenocorticotropic Hormone; D001012:Aorta, Abdominal / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
Die passager reduzierte Nebennierenfunktion nach grossen gefässchirurgischen Eingriffen.