title: Huntington's disease. A decade of progress.
abstract: Considerable investigative attention has been accorded to HD in the past decade. These efforts have been rewarded by substantive advances in our understanding of the clinical features and pathologic consequences of this disorder. The recent linkage of HD to a DNA segment mapped to chromosome 4 is a remarkable achievement that will help sustain investigative efforts and lead to therapeutic benefits for patients and families.
mesh_terms: D001921:Brain / Q000378:metabolism / Q000473:pathology; D002900:Chromosomes, Human, 1-3; D005817:Genetic Counseling; D006801:Humans; D006816:Huntington Disease / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D009435:Synaptic Transmission; D005680:gamma-Aminobutyric Acid / Q000502:physiology
chemical_list: D005680:gamma-Aminobutyric Acid