Structure of the polymorphic feline c-myc oncogene locus.
Two feline c-myc DNA clones (CM-2 and CM-3), isolated from a cat DNA library, are structurally very similar. However, they differ at a SmaI site in exon III which is present only in CM-2. In the outbred feline population, cats heterozygous for this site or homozygous for the CM-3-type gene have been observed. The results provide a physical map of the feline c-myc locus, and define hitherto unidentified alleles of this gene.
D000483:Alleles; D000818:Animals; D001483:Base Sequence; D002371:Cat Diseases / Q000235:genetics; D002415:Cats / Q000235:genetics*; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D004273:DNA, Neoplasm / Q000032:analysis; D004274:DNA, Recombinant / Q000032:analysis*; D015252:Deoxyribonucleases, Type II Site-Specific; D005796:Genes; D009369:Neoplasms / Q000235:genetics / Q000662:veterinary; D009857:Oncogenes; D011110:Polymorphism, Genetic
D004273:DNA, Neoplasm; D004274:DNA, Recombinant; D004262:DNA Restriction Enzymes; C025651:CCCGGG-specific type II deoxyribonucleases; D015252:Deoxyribonucleases, Type II Site-Specific