[Therapy of orthostatic dysregulation. Comparative studies on anti-hypotensive sympathomimetics with a tilt-table test].
In 7 patients suffering from orthostatic hypotension the early behaviour of arterial mean blood pressure was studied in the tilting table experiment under influence of etilefrine, norfenefrine, gepefrine (D-(+)-1-(3-hydroxyphenyl)-2-aminopropan-(2R, 3R)-hydrogentartrat) and of its I-isomere. Significant improvement of early orthostatic disregulation of the arterial pressure could be only observed under gepefrine. Amelioration seems to be induced by sensitization of the pressoreceptors.
D000328:Adult; D005039:Etilefrine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013566:Sympathomimetics / Q000627:therapeutic use*
D013566:Sympathomimetics; D005039:Etilefrine
Zur therapie der orthostatischen Dysregulation. Vergleichende Untersuchungen antihypotensiv wirksamer Sympathikomimetika im Kipptisch-Versuch.