[Slow cerebral potentials after administration of flunitrazepam to subjects with sleep disorders].
12 patients admitted for neurological diseases and suffering from sleep disturbances, were given Flunitrazepam and placebo (double blind test) in a single evening dose of 1 and 2 mg. Morning recordings of the expectation wave according to G. Walter's technique did not reveal significant changes in wave morphology, amplitude and latency. The psychophysical conditions of patients and their reaction times did not differ after Flunitrazepam and placebo. The research shows, on the one hand the value of the electrophysiological investigation method and, on the other, the absence of residual effects in the morning after Flunitrazepam administration.
D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001921:Brain / Q000187:drug effects; D004341:Drug Evaluation; D004569:Electroencephalography; D005260:Female; D005445:Flunitrazepam / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D009422:Nervous System Diseases / Q000188:drug therapy*; D012893:Sleep Wake Disorders / Q000188:drug therapy*
D014151:Anti-Anxiety Agents; D005445:Flunitrazepam
Potenziali lenti cerebrali dopo somministrazione di flunitrazepam a soggetti con disturbi del sonno.