title: Cytotoxic immune response of puppies to feline sarcoma virus induced tumors.
abstract: The cytotoxic immune response of puppies to feline sarcoma virus induced tumors was studied. Neonatal puppies were compared with adolescent dogs. Three different types of cytotoxicity were investigated: complement dependent cytotoxicity, T-cell-mediated cytotoxicity and antibody dependent cellular cytotoxicity. The relationship between the spontaneous regression of the sarcoma and the development of the immune system of the puppies is discussed.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000920:Antibody-Dependent Cell Cytotoxicity; D003165:Complement System Proteins / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D004285:Dogs; D005253:Sarcoma Viruses, Feline; D012513:Sarcoma, Experimental / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014412:Tumor Virus Infections / Q000276:immunology*
chemical_list: D003165:Complement System Proteins