Hepatic injury due to environmental agents.
Environmental agents are capable of producing many of the same patterns of liver injury observed in diseases of the liver caused by virus, infection and drugs, and by metabolic or genetic defects. The long-term consequences, especially with respect to contact with animal carcinogens, are unknown. Although substantial progress has been made in identifying the hepatic enzymes involved in the metabolic activation and detoxification of environmental substances, the area remains an important subject for future research.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced* / Q000503:physiopathology; D056486:Chemical and Drug Induced Liver Injury; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000009:adverse effects*; D006394:Hemangiosarcoma / Q000139:chemically induced*; D006801:Humans; D008658:Inactivation, Metabolic; D008099:Liver / Q000378:metabolism; D008107:Liver Diseases / Q000503:physiopathology; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000503:physiopathology
D004785:Environmental Pollutants