title: [The influence of flunitrazepam on the blood gases during subarachnoid block in geriatric patients (author's transl)].
abstract: Fifty-three geriatric patients under subarachnoid block for orthopaedic surgery received flunitrazepam 0.3-0.4 mg intravenously. Blood gases were checked while breathing room air. This dose caused a significant but small respiratory depression (p less than 0.05). These results confirm other reports on flunitrazepam, but used without spinal anaesthesia. There was no case, however, who needed ventilatory support. Top up doses up to a total of 1 mg caused no further significant changes. We feel that Flunitrazepam is a useful drug for sedation during regional block including poor risk patients.
mesh_terms: D000368:Aged; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D002245:Carbon Dioxide / Q000097:blood*; D005445:Flunitrazepam / Q000494:pharmacology*; D006801:Humans; D009407:Nerve Block; D010100:Oxygen / Q000097:blood*; D011229:Preanesthetic Medication; D013346:Subarachnoid Space
chemical_list: D014151:Anti-Anxiety Agents; D002245:Carbon Dioxide; D005445:Flunitrazepam; D010100:Oxygen
vernacular_title: Beeinflussung der Blutgaswerte geriatrischer Patienten durch Flunitrazepam während subarachnoidaler Blockade.