Effects of vitamin A in the presence of vitamins D3, E, K1 on red cell membrane structure.
The incubation of erythrocyte ghosts with mixtures of vitamins A+D3, A+E, A+K1 produces decrease or increase of fluorescence anisotropy r of the DPH probe, depending on the vitamin/vitamin ratio. We found a correlation between the order parameter S and cell fusion phenomena observed by phase contrast microscopy.
D000818:Animals; D002645:Chickens; D002762:Cholecalciferol / Q000494:pharmacology*; D004347:Drug Interactions; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000648:ultrastructure*; D005454:Fluorescence Polarization; D006801:Humans; D008858:Microscopy, Phase-Contrast; D014801:Vitamin A / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology*; D010837:Vitamin K 1 / Q000494:pharmacology*
D014801:Vitamin A; D014810:Vitamin E; D002762:Cholecalciferol; D010837:Vitamin K 1