title: NALL-1, an acute lymphoblastic leukemia cell line with peroxidase activity.
abstract: All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in greater than 80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell.
mesh_terms: D000293:Adolescent; D002460:Cell Line; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000201:enzymology* / Q000235:genetics / Q000276:immunology / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D009195:Peroxidase; D010544:Peroxidases / Q000378:metabolism*; D010641:Phenotype
chemical_list: D007527:Isoenzymes; D010544:Peroxidases; D009195:Peroxidase