Host defenses in experimental rickettsialpox: resistance of C3H mouse sublines.
Eight sublines of C3H mice were tested for their resistance to lethal infection with Rickettsia akari,. strain Kaplan. C3H/HeJ mice were unique in their susceptibility to approximately one plaque-forming unit of rickettsiae. This lack of resistance is apparently due to a mutation in the mouse strain which occurred after 1950.
D000818:Animals; D007113:Immunity, Innate; D051379:Mice; D008809:Mice, Inbred C3H; D009154:Mutation; D012282:Rickettsia Infections / Q000235:genetics / Q000276:immunology*