Release of multivesicular bodies from platelets as observed in SEM.
Scanning EM was used to study platelet shape changes induced by collagen in citrated PRP. While using a modified fixation technique known to protect phospholipids from extraction during alcohol dehydration a release of multivesicular bodies from platelets was observed. Maximum frequency of their appearance correlated with the onset of a release reaction from platelets as seen in an aggregometer curve. Depicted structures may thus be related to the release of different platelet constituents.
D001792:Blood Platelets / Q000648:ultrastructure*; D003094:Collagen / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning
D003094:Collagen