title: Mechanisms of opioid tolerance and dependence.
mesh_terms: D000818:Animals; D004361:Drug Tolerance; D004723:Endorphins / Q000502:physiology*; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine; D006168:Guinea Pigs; D006801:Humans; D006822:Hybrid Cells / Q000502:physiology; D007082:Ileum / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000502:physiology; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology*; D019966:Substance-Related Disorders / Q000209:etiology*; D014649:Vas Deferens / Q000502:physiology
chemical_list: D004723:Endorphins; D011957:Receptors, Opioid; D009270:Naloxone; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine