[Clinical studies on sulbactam/cefoperazone in the field of obstetrics and gynecology].
Sulbactam cefoperazone (SBT/CPZ), a combination drug of SBT and CPZ, was administered to 5 cases with obstetrical and gynecological infections in a daily dose of 2-6 g for 3-5 days. Clinical efficacy was good in 4 cases and poor in 1 case with adnexitis. Bacteriologically, organisms were detected in 2 out of 5 cases, beta-lactamase producing P. aeruginosa was detected in 1 case, but, their bacteriological responses were not clarified. Neither side effect nor abnormal laboratory findings due to this drug were observed. From the results we concluded that SBT/CPZ was an effective and safe antibiotic in the field of obstetrics and gynecology.
D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000188:drug therapy*; D002438:Cefoperazone / Q000008:administration & dosage*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D007263:Infusions, Parenteral; D008875:Middle Aged; D010397:Penicillanic Acid / Q000008:administration & dosage*; D011247:Pregnancy; D013407:Sulbactam; D065093:beta-Lactamase Inhibitors
D004338:Drug Combinations; D065093:beta-Lactamase Inhibitors; D002438:Cefoperazone; D010397:Penicillanic Acid; D013407:Sulbactam