[Experimental study of the antimetastatic activity of thaliblastin].
The antimetastatic effect of thaliblastine alkaloid isolated from Thalictrum min. ssp. elatum was evaluated using Wexler's technique for accurate identification of experimental pulmonary metastases. Thaliblastine was found to inhibit the growth of lung metastases as compared with the control.
D000477:Alkylating Agents / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001060:Aporphines / Q000627:therapeutic use*; D005260:Female; D006589:Hexestrol / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy*
D000477:Alkylating Agents; D001060:Aporphines; D006589:Hexestrol; C043879:phenestrol; C043880:4,4-bis(acetylsarcosyl)synestrol
Eksperimental'noe izuchenie antimetastaticheskoĭ aktivnosti taliblastina.