title: [Dynamics of morphologic changes in joint innervation during hypokinesia--a space flight model factor].
abstract: Using statistical treatment, a neuromorphological examination of the joint capsule of rats exposed to hypokinesia for 7, 15, 20, 30, 40, and 60 days was carried out. The exposure to 7 days caused an increase in the number of reactively changed nerve fibers and receptors. The exposure to 15 days resulted in a significant increase of the number of nerve fibers with destructive changes that involved mostly large-caliber fibers. However, 20- and, especially, 30-day hypokinesia was followed by a significant reduction of destructive changes. After 40- and 60-day exposure they again became very distinct. This suggested a wave-like pattern of structural changes. At every stage of experimental hypokinesia all the compartments of the joint nervous apparatus showed adaptive-compensatory reactions.
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D007596:Joints / Q000294:innervation*; D008954:Models, Biological; D009068:Movement; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D051381:Rats; D011984:Sensory Receptor Cells / Q000473:pathology; D013026:Space Flight; D013997:Time Factors
vernacular_title: Dinamika morfologicheskikh izmeneniĭ nervnogo apparata sustavov pri gipokinezii--model'nom faktore kosmicheskogo poleta.