[Catecholamines and the enzymes of their synthesis in the adrenal medulla of rats after a flight on the Cosmos-936 biosatellite].
In the adrenals of weightless and centrifuged rats flown for 18.5 days onboard the biosatellite Cosmos-936 indicators of the activity of the adrenomedullary system, i.e. the content of catecholamines and activity of the enzymes involved in their synthesis--tyrosine hydroxylase and dopamine-beta-hydroxylase--were measured. It was found that none of the indicators changed postflight. These findings show that a prolonged exposure of rats to weightlessness does not act as a strong stressor for the adrenomedullary system.
D000313:Adrenal Medulla / Q000378:metabolism*; D000818:Animals; D002395:Catecholamines / Q000096:biosynthesis*; D004299:Dopamine beta-Hydroxylase / Q000378:metabolism; D004789:Enzyme Activation; D008297:Male; D010625:Phenylethanolamine N-Methyltransferase / Q000378:metabolism; D051381:Rats; D013026:Space Flight; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism; D014586:USSR
D002395:Catecholamines; D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase; D010625:Phenylethanolamine N-Methyltransferase
Sostoianie katekholaminov i fermentov ikh sinteza v mozgovom sloe nadpochechnikov krys posle poleta na biosputnike "Kosmos-936".