Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease.
D000328:Adult; D000818:Animals; D003238:Connective Tissue / Q000201:enzymology; D006801:Humans; D003012:Microbial Collagenase / Q000037:antagonists & inhibitors*; D010510:Periodontal Diseases / Q000188:drug therapy* / Q000201:enzymology; D010514:Periodontal Pocket / Q000188:drug therapy / Q000201:enzymology; D010519:Periodontium / Q000201:enzymology*; D011817:Rabbits; D051381:Rats; D013754:Tetracyclines / Q000494:pharmacology* / Q000627:therapeutic use
D013754:Tetracyclines; D003012:Microbial Collagenase