An electron microscopic study of solar ganglia in piglets infected with Aujeszky's disease virus.
Ten 2-day-old piglets were inoculated intranasally with Aujeszky's disease virus and their solar ganglia were examined by light and electron microscopy. The cytopathic change noticed was neuronal and glial cell degeneration. It was invariably associated with the virus replicated within the cells. All the main stages of virus development were observed in the degenerated ganglionic cells. Characteristically, plexiform vermicellar array and electron-dense tubular filaments were detected in a part of the nuclei of the infected neuron.
D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology; D005728:Ganglia, Sympathetic / Q000382:microbiology / Q000473:pathology / Q000648:ultrastructure*; D011558:Herpesvirus 1, Suid / Q000648:ultrastructure; D009336:Necrosis; D009410:Nerve Degeneration; D011557:Pseudorabies / Q000382:microbiology / Q000473:pathology*; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology / Q000473:pathology*; D014771:Virion / Q000648:ultrastructure