title: A simple method for the evaluation of antiseptic and disinfectant virucidal activity.
abstract: A simple method for evaluating the virucidal activity of water-soluble antiseptic and disinfectant products using poliovirus type 1 (Sabin strain) is described. Using a commercial concentrator, kinetic studies of four products were carried out. It was shown that 2% glutaraldehyde and 5% povidone iodine are rapidly virucidal. 0.2% glutaraldehyde and 2.5% noxythiolin (37 degrees C) are considerably less effective. 0.05% chlorhexidine digluconate has no virucidal activity.
mesh_terms: D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D004341:Drug Evaluation; D005976:Glutaral / Q000494:pharmacology; D009677:Noxythiolin / Q000494:pharmacology; D017955:Poliovirus / Q000187:drug effects*; D011206:Povidone-Iodine / Q000494:pharmacology
chemical_list: D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D009677:Noxythiolin; D011206:Povidone-Iodine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine; D005976:Glutaral