Electrophoretic separation of alkaline phosphatase isoenzymes compared with alkaline phosphatase and gamma-glutamyltransferase in hepatobiliary diseases.
Electrophoretic separation of serum alkaline phosphatase fractions and measurement of serum alkaline phosphatase and serum gamma-glutamyltransferase were carried out in 82 consecutive patients with suspected hepatobiliary disease to investigate the usefulness of the three tests in distinguishing between parenchymatous hepatic disease and occlusive hepatobiliary disease. It was concluded that measurement of total serum alkaline phosphatase was superior to the two other tests.
D000469:Alkaline Phosphatase / Q000097:blood*; D002779:Cholestasis / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008107:Liver Diseases / Q000175:diagnosis*; D005723:gamma-Glutamyltransferase / Q000097:blood*
D007527:Isoenzymes; D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase