Epinephrine inhibits adenylate cyclase and stimulates a GTPase in human platelet membranes via alpha-adrenoceptors.
D000067956:Adenylyl Cyclase Inhibitors; D001792:Blood Platelets / Q000187:drug effects / Q000201:enzymology*; D004837:Epinephrine / Q000494:pharmacology*; D020558:GTP Phosphohydrolases / Q000097:blood*; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D066298:In Vitro Techniques; D007700:Kinetics; D010646:Phentolamine / Q000494:pharmacology; D010744:Phosphoric Monoester Hydrolases / Q000097:blood*; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000378:metabolism*
D000067956:Adenylyl Cyclase Inhibitors; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D006160:Guanosine Triphosphate; D010744:Phosphoric Monoester Hydrolases; D020558:GTP Phosphohydrolases; D004837:Epinephrine; D010646:Phentolamine