Further studies on the in vivo effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on the liver microsomal drug oxidation system in rats.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism; D042966:Cytochrome-B(5) Reductase; D003580:Cytochromes / Q000378:metabolism; D015786:Cytochromes b5; D004579:Electron Transport / Q000187:drug effects; D007700:Kinetics; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008314:Malonates / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000378:metabolism*; D009245:NADH Dehydrogenase / Q000378:metabolism; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013230:Stearoyl-CoA Desaturase / Q000378:metabolism
D003580:Cytochromes; D008054:Lipid Peroxides; D008314:Malonates; D004364:Pharmaceutical Preparations; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; D013230:Stearoyl-CoA Desaturase; D003579:Cytochrome Reductases; D042966:Cytochrome-B(5) Reductase; D009245:NADH Dehydrogenase; C024808:diisopropyl 1,3-dithiol-2-ylidenemalonate