Identical twins with Alzheimer's disease.
Genetically proven identical twin sisters with Alzheimer's disease are reported. Both sisters at the age of fifty years developed a dementing illness. Their mother and maternal grandmother developed at the same age a similar illness. It is suggested that in some cases of familial Alzheimer's disease the condition is inherited by a single mutant gene.
D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics* / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D004200:Diseases in Twins / Q000235:genetics*; D005190:Family; D005192:Family Health; D005260:Female; D006801:Humans; D016874:Neurofibrillary Tangles / Q000473:pathology; D014430:Twins, Monozygotic