[Diastrophic dwarfism (author's transl)].
On the basis of their own patient the authors discuss clinical and radiological features of diastrophic dwarfism. In this rare disorder the infant is dwarfed, the limbs are shortened. It is associated with marked talipes equinovarus, limited movements and contractures of other joints. Dislocation in the hip or knee and development of kyphoscoliosis leads to furhter deformity. As aetiopathogenesis the authors consider the role of infection in the mother during her early pregnancy or teratogenic aspects of some drugs (tetracyclines, septrim).
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001848:Bone Diseases, Developmental / Q000139:chemically induced / Q000235:genetics; D004392:Dwarfism / Q000139:chemically induced / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy
D000900:Anti-Bacterial Agents
Nanosomia diastrophica.