title: [Physicochemical bases of the search for pharmacologically active substances among polyfunctional macroheterocycles].
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D000889:Anti-Arrhythmia Agents; D000890:Anti-Infective Agents; D000917:Antibody Formation / Q000187:drug effects; D000970:Antineoplastic Agents; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology; D002462:Cell Membrane / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004988:Ethers, Cyclic / Q000494:pharmacology / Q000633:toxicity; D006571:Heterocyclic Compounds / Q000494:pharmacology* / Q000633:toxicity; D007111:Immunity, Cellular / Q000187:drug effects; D007473:Ion Channels / Q000187:drug effects; D046911:Macromolecular Substances; D008564:Membrane Potentials / Q000187:drug effects; D051379:Mice; D009200:Myocardial Contraction / Q000187:drug effects; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors
chemical_list: D000276:Adjuvants, Immunologic; D000889:Anti-Arrhythmia Agents; D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D001643:Bridged Bicyclo Compounds; D004988:Ethers, Cyclic; D006571:Heterocyclic Compounds; D007473:Ion Channels; D046911:Macromolecular Substances; D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: Fiziko-khimicheskie osnovy poiska farmakologicheski aktivnykh veshchestv v riadu polifunktsional'nykh makrogeterotsiklov.