[Glomerulus-like structures in Wilms' tumor].
Twenty-three cases of Wilms' tumour with numerous glomerulus-like structures (GLS) were studied. 74% children were admitted to the hospital with metastases or the latter developed within 2-3 months after a surgical operation. 5 out of the 8 children with bilateral Wilms' tumours had in the tumours an increased number of the GLS. There are some features which allow the GLS to be distinguished from the true renal corpuscles: the absence of capillaries and mesangium, structural polymorphism the presence of several pseudopapillae originating from different areas of the capsule. The possibility is shown to use these criteria in the differential diagnosis of renal sarcomas in children and sarcomatous variants of Wilms' tumour, in the determination of pseudocapsule infiltration and the degree of tumour tissue survival after the active therapy.
D002648:Child; D002675:Child, Preschool; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007223:Infant; D007678:Kidney Glomerulus / Q000473:pathology*; D007680:Kidney Neoplasms / Q000473:pathology*; D008854:Microscopy, Electron; D009362:Neoplasm Metastasis; D009396:Wilms Tumor / Q000473:pathology*
Glomerulopodobnye struktury v opukholi Vil'msa.