title: Cryptorchidism in the Prader-Willi syndrome.
abstract: Among 30 male children seen for the Praer-Willi syndrome 21 had at least 1 undescended testis (70 per cent). In 14 of the 30 patients both testes were undescended (45 per cent). Of 18 patients observed for a period 4 (22 per cent) had late spontaneous descent of 6 testes. Gonadotropin treatment facilitated descent in 3 of 4 patients. Testicular biopsy showed a Sertoli-cell-only appearance in 4 patients. The usual indications for orchiopexy of undescended testes may need to be modified in patients with the Prader-Willi syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006062:Gonadotropins / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011218:Prader-Willi Syndrome / Q000150:complications* / Q000473:pathology; D013737:Testis / Q000473:pathology
chemical_list: D006062:Gonadotropins