[Age-related characteristics of the effect of potassium glutamate on cell membranes].
The effect of potassium glutaminate on the activity of some enzymes and lipid peroxidation of liver and kidney endoplasmic reticulum membranes was studied in young and old rats. It was shown that in old animals, the drug increased the activity of enzymes of liver endoplasmic reticulum membranes which metabolize the substances of endogenous and exogenous origin, and reduced the renal content of malonic dialdehyde, the final product of lipid peroxidation. The latter favoured the improvement of drug biotransformation and elimination of the aging body.
D000375:Aging / Q000187:drug effects*; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects*; D004721:Endoplasmic Reticulum / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D005971:Glutamates / Q000494:pharmacology*; D018698:Glutamic Acid; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D051381:Rats
D005971:Glutamates; D008054:Lipid Peroxides; D018698:Glutamic Acid
Vozrastnye osobennosti vliianiia kaliia glutaminata na kletochnye membrany.