A study on the effects of some drugs on DOCA induced hypertension in the rat.
Chronic treatment with various drugs reduced the increase in arterial blood pressure, the ventricular hypertrophy and the thickening of pulmonary arterial and arteriolar walls.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D006332:Cardiomegaly / Q000139:chemically induced*; D003900:Desoxycorticosterone; D004232:Diuretics / Q000494:pharmacology; D006973:Hypertension / Q000139:chemically induced / Q000503:physiopathology*; D007217:Indoramin / Q000494:pharmacology; D008297:Male; D008790:Metoprolol / Q000494:pharmacology; D011224:Prazosin / Q000494:pharmacology; D011651:Pulmonary Artery / Q000187:drug effects / Q000503:physiopathology; D051381:Rats; D014700:Verapamil / Q000494:pharmacology
D000316:Adrenergic alpha-Agonists; D004232:Diuretics; D007217:Indoramin; D003900:Desoxycorticosterone; D014700:Verapamil; D008790:Metoprolol; D011224:Prazosin