Warming-induced hyperpolarization of cardiac muscle cells and snail neurones: interpretation based on temperature transition of cooperatively linked surface anionic sites between K+ and Na+ adsorbing states.
The resting potential of a variety of living cells exhibits pronounced hyperpolarization when the cooled cells are brought to a higher temperature. It was shown that this phenomenon can be quantitatively described by the surface adsorption theory of the cell electrical potential in terms of a cooperative temperature transition of the protein-ion-water system at the cell surface. As such, the basic mechanism resembles the temperature transition demonstrated for the bulk phase K+-Na+ distribution in these and similar cells. The paper also discusses the resting potentials of frog muscles and squid axons which do not exhibit hyperpolarization on warming.
D000818:Animals; D001369:Axons / Q000502:physiology; D002417:Cattle; D002462:Cell Membrane / Q000502:physiology; D049832:Decapodiformes; D006168:Guinea Pigs; D006358:Hot Temperature; D066298:In Vitro Techniques; D007473:Ion Channels / Q000502:physiology; D008564:Membrane Potentials; D009132:Muscles / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D010210:Papillary Muscles / Q000502:physiology*; D011188:Potassium / Q000378:metabolism*; D011817:Rabbits; D011896:Rana temporaria; D051381:Rats; D012756:Sheep; D012908:Snails; D012964:Sodium / Q000378:metabolism*
D007473:Ion Channels; D012964:Sodium; D011188:Potassium