[7-Methyltryptophan9]-beta-corticotropin-(1-24): a hyperactive Synacthen analogue.
[7-Methyltryptophan9]-beta-corticotropin-(1-24) has been synthesised. In an isolated adrenal cell bioassay, it has 2.7 times the steroidogenic activity of beta-corticotropin-(1-24) (Synacthen).
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives*; D001681:Biological Assay; D003366:Cosyntropin / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D008745:Methylation; D013329:Structure-Activity Relationship; D014364:Tryptophan / Q000031:analogs & derivatives
D003366:Cosyntropin; C044150:cosyntropin, 7-meTrp(9)-; D014364:Tryptophan; D000324:Adrenocorticotropic Hormone