title: Agglutinin responses to Salmonella pullorum in Japanese quail selected for plasma cholesterol response to adrenocorticotropin and a model describing the dynamics of the response.
abstract: Japanese quail from the S16 generation of lines selected for high (HR) and low (LR) plasma cholesterol response to adrenocorticotropin (ACTH), and the randombred control line (C) from which the selected lines had been derived, were immunized with a heat-killed Salmonella pullorum antigen. Plasma from blood samples taken at 0,5,8, and 12 days postimmunization was titered for total agglutinin levels. A quadratic equation and its first derivative, calculated for each bird, produced mean values by line for maximum titers, mean day of maximum titer, and rate of titer decline. Results indicated that the LR line had significantly lower titers than the HR or C lines but that the HR line reached maximum titer later than the LR line. The rate of titer decline was fastest in the C line.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000373:Agglutinins / Q000032:analysis*; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D000942:Antigens, Bacterial / Q000276:immunology; D002784:Cholesterol / Q000097:blood*; D003370:Coturnix / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D005260:Female; D008297:Male; D008954:Models, Biological; D011784:Quail / Q000276:immunology*; D012475:Salmonella / Q000276:immunology*
chemical_list: D000373:Agglutinins; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000324:Adrenocorticotropic Hormone; D002784:Cholesterol