Serum lipids and high-density-lipoprotein cholesterol in women on long-term sustained low-dose IUD treatment with levonorgestrel.
Serum concentrations of high density lipoprotein cholesterol, total cholesterol, and triglycerides were measured in 31 women using levonorgestrel-releasing intrauterine devices and in 30 matched controls. There was no statistically significant difference in the mean values of all three lipid parameters between the levonorgestrel-treated subjects and the control subjects. The mean value for serum triglycerides was 0.79 +/- 0.33 mmol/l in the study group and 0.74 +/- 0.23 mmol/l in the control group. The mean cholesterol values were 5.19 +/- 0.91 mmol/l and 5.39 +/- 0.71 mmol/l in the study group and control group, respectively. The mean serum concentration of high density lipoprotein cholesterol was 1.61 +/- 0.37 mmol/l in the study group and 1.77 +/- 0.38 mmol/l in the control group.
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated; D016912:Levonorgestrel; D008075:Lipoproteins, HDL / Q000097:blood*; D009644:Norgestrel / Q000008:administration & dosage* / Q000494:pharmacology; D011247:Pregnancy; D013237:Stereoisomerism; D014280:Triglycerides / Q000097:blood*
D008075:Lipoproteins, HDL; D014280:Triglycerides; D009644:Norgestrel; D016912:Levonorgestrel; D002784:Cholesterol