title: Activation of cGMP phosphodiesterase by purified green rod pigment from frog retina.
abstract: Activation of cGMP phosphodiesterase(PDE) of frog rod outer segments (ROS) by purified green rod pigment (GRP) was analyzed. GRP activated PDE in a similar manner to purified rhodopsin. This activation required illumination of the pigment and presence of GTP.
mesh_terms: D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation; D007700:Kinetics; D010786:Photoreceptor Cells / Q000201:enzymology*; D011892:Rana catesbeiana; D012168:Retinal Pigments / Q000302:isolation & purification / Q000502:physiology*; D012243:Rhodopsin / Q000502:physiology; D012374:Rod Cell Outer Segment / Q000201:enzymology*
chemical_list: D012168:Retinal Pigments; D012243:Rhodopsin; D015106:3',5'-Cyclic-GMP Phosphodiesterases