[The therapeutical profit of encymatic analysis of serum digoxin on geriatric patients (author's transl)].
The develpment of an encymimmunological method of analysis for serum digoxin level makes it possible to analyse serum digoxin in hospital as well as in practice. The therapeutical profit of this encymimmunological method was tested with 32 patients being digitalised because of having a cardiac insufficiency besides various diseases and different degree of disablement. The therapeutical profit should be an extended individual radius of action. There are compared two periods of therapy. In the first way the level of serum digoxin was unknown and in the second way the level of serum digoxin was known and taken into consideration by the medical treatment. The dose of digitalis was fixed under consideration of all clinical symptoms and not only under consideration of the level of serum digoxin. That the method of analysis of serum digoxin is useful was demonstrated by a sixth part of the patients, where a wrong assessment of clinical symptoms turned out and could be corrected. The clinical symptomatic of overdigitalisation was easier to recognise and less necessary to be changed than underdigitalisation.
D000368:Aged; D004077:Digoxin / Q000097:blood* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male
D004077:Digoxin
Der therapeutische Nutzen der enzymatischen Serumdigoxinbestimmung für geriatrische Patienten.