Seasonal variation in urinary excretion of calcium, magnesium and phosphate in manic-melancholic patients.
The 24-hr urinary excretion of calcium, magnesium and phosphate was measured in 76 normal control persons, 95 manic-melancholic patients not on lithium treatment and 74 lithium-treated manic-melancholic patients. The mean value of the urinary excretion for each of the four seasons during a 5-year period was calculated. The normal control persons had a higher excretion of calcium during the summer months than during the rest of the year; this seasonal variation was not present in the two groups of manic-melancholic patients. Previously reported changes in electrolyte metabolism during lithium treatment were confirmed, but some of the results varied with the season.
D001714:Bipolar Disorder / Q000188:drug therapy / Q000652:urine*; D002118:Calcium / Q000652:urine*; D002712:Chlorides / Q000627:therapeutic use; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D018021:Lithium Chloride; D008274:Magnesium / Q000652:urine*; D008297:Male; D010710:Phosphates / Q000652:urine*; D012621:Seasons
D002712:Chlorides; D010710:Phosphates; D008094:Lithium; D018021:Lithium Chloride; D008274:Magnesium; D002118:Calcium