The evidential value of peptidase A as a semen typing system.
Human erythrocyte peptidase A (Pep A) displays a genetic polymorphism in blacks. Its occurrence in human semen was examined for its possible use as a semen typing system. Studies by starch gel electrophoresis, in which the Pep A was located by an improved method, were carried out on semen, semen stains, and vaginal swabs taken at known times after intercourse. In addition, a large number of vaginal swabs, negative for semen, were taken from females throughout their menstrual cycles and examined for Pep A activity. The results indicated that Pep A typing could be carried out on semen and semen stains. However, it was possible to determine the Pep A type on vaginal swabs only when they had been taken within about 3 h after intercourse.
D004150:Dipeptidases / Q000235:genetics*; D004592:Electrophoresis, Starch Gel; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D012661:Semen / Q000201:enzymology*; D014626:Vaginal Smears
D004150:Dipeptidases; C031499:CNDP2 protein, human