Activation of cGMP phosphodiesterase by purified green rod pigment from frog retina.
Activation of cGMP phosphodiesterase(PDE) of frog rod outer segments (ROS) by purified green rod pigment (GRP) was analyzed. GRP activated PDE in a similar manner to purified rhodopsin. This activation required illumination of the pigment and presence of GTP.
D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation; D007700:Kinetics; D010786:Photoreceptor Cells / Q000201:enzymology*; D011892:Rana catesbeiana; D012168:Retinal Pigments / Q000302:isolation & purification / Q000502:physiology*; D012243:Rhodopsin / Q000502:physiology; D012374:Rod Cell Outer Segment / Q000201:enzymology*
D012168:Retinal Pigments; D012243:Rhodopsin; D015106:3',5'-Cyclic-GMP Phosphodiesterases