[Caprine arthritis-encephalitis virus (CAEV). Short review].
After a short history, this work shows frequency of the articular form of the disease in France, and isolation of the virus. Although related to retrovirus, CAEV and maedi-visna have some differences: tropism of CAEV only for goats, low replication and expression in vitro, characteristic differences in protein composition. The virus seems to be transmitted during neonatal life; aerial transmission is still unclear. Separation of affected and non-affected goats is the only eradication technique when flocks are highly infected. An intervention a non-specific parameters is necessary to limit the spreading of the disease. Medical prophylaxis is non-existent. It is important to obtain a specific antigen in ELISA test for earlier detection of affected animals. Moreover, this research work could be a good model for further investigation into the rheumatoid-like syndrome in man.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001170:Arthritis, Infectious / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D004660:Encephalitis / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D006041:Goats / Q000382:microbiology*; D012190:Retroviridae / Q000276:immunology / Q000302:isolation & purification* / Q000648:ultrastructure; D012192:Retroviridae Infections / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D013577:Syndrome / Q000662:veterinary; D013583:Synovial Membrane / Q000382:microbiology
D000914:Antibodies, Viral
Virus de l'arthrite-encéphalite caprine (CAEV). Bréve revue.