Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2.
Terminal respiratory failure was reversed in three patients with a combination of extra-corporeal CO2 removal through a membrane lung and oxygen diffusion into the diseased lungs between mechanical breaths induced at a frequency of 2-3/min. The technique seems to prevent the pulmonary barotrauma and extrapulmonary derangements caused by conventional mechanical ventilation.
D000208:Acute Disease; D000328:Adult; D001187:Artificial Organs; D002245:Carbon Dioxide / Q000097:blood*; D005112:Extracorporeal Circulation / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation / Q000379:methods*; D008170:Lung Compliance; D008875:Middle Aged; D010107:Oxygenators, Membrane; D011175:Positive-Pressure Respiration / Q000379:methods*; D011247:Pregnancy; D012131:Respiratory Insufficiency / Q000628:therapy*; D013990:Tidal Volume
D002245:Carbon Dioxide