title: Overall-response parameter analysis applied to butyrophenones.
abstract: If the first (and second) principal component function of psycho pharmacologically defined parameters rationalize most of the information, the component may be regressed against physicochemical features in order to study quantitative relationships between structure and function. An example is the analysis of butyrophenones.
mesh_terms: D014150:Antipsychotic Agents / Q000008:administration & dosage; D002090:Butyrophenones / Q000008:administration & dosage; D055598:Chemical Phenomena; D002621:Chemistry; D013223:Statistics as Topic; D013329:Structure-Activity Relationship
chemical_list: D014150:Antipsychotic Agents; D002090:Butyrophenones