Metabolism and covalent binding of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane (o,p,'-DDD). Correlation between adrenocorticolytic activity and metabolic activation by adrenocortical mitochondria.
D000302:Adrenal Cortex / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D002855:Chromatography, Thin Layer; D003634:DDT / Q000378:metabolism; D004285:Dogs; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D008939:Mitotane / Q000378:metabolism* / Q000494:pharmacology; D011817:Rabbits; D051381:Rats
D008939:Mitotane; D003634:DDT