[Clinical and bacteriological efficiency of sulbactam/cefoperazone in gynecological infectious diseases].
The combined antibiotics, sulbactam/cefoperazone (SBT/CPZ), was administrated intravenously to 10 patients with various kinds of gynecological infectious diseases and the efficiency of the drug was investigated clinically or bacteriologically. The results obtained were as follows. The clinical and bacteriological efficiency rate of SBT/CPZ on gynecological infectious diseases was determined as about 100 per cent and 75 per cent. Three species out of 11 isolated bacteria produced beta-lactamase. Two cases out of 3 beta-lactamase positive bacteria were disappeared in the materials obtained from the patients after the treatment of the drug. No remarkable side effect except for 1 buccal exanthema and 1 genital candidiasis was detected during the administration course of the drug.
D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002438:Cefoperazone / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007263:Infusions, Parenteral; D008875:Middle Aged; D010397:Penicillanic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy; D013407:Sulbactam; D065093:beta-Lactamase Inhibitors
D004338:Drug Combinations; D065093:beta-Lactamase Inhibitors; D002438:Cefoperazone; D010397:Penicillanic Acid; D013407:Sulbactam