title: Candidiasis in cancer patients.
abstract: Disseminated candidiasis is likely to become an increasing problem in cancer patients. It has occurred in patients undergoing intensive chemotherapy, thermotherapy, and bone marrow transplant. The availability of broad-spectrum cephalosporins with biliary excretion is likely to increase the problem. Although localized candidiasis responds to both topical and parenteral therapy, systemic candidiasis is often fatal, especially in neutropenic patients. A major obstacle to control of this infection is inadequate diagnostic techniques. It is to be hoped that continuing research will yield more effective diagnostic and therapeutic measures.
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000908:Antibodies, Fungal / Q000276:immunology; D002177:Candidiasis / Q000175:diagnosis / Q000209:etiology*; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D007938:Leukemia / Q000150:complications; D008825:Miconazole / Q000627:therapeutic use; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D011014:Pneumonia / Q000382:microbiology
chemical_list: D000908:Antibodies, Fungal; D002511:Cephalosporins; D008825:Miconazole; D000666:Amphotericin B; D007654:Ketoconazole