Cytotoxic immune response of puppies to feline sarcoma virus induced tumors.
The cytotoxic immune response of puppies to feline sarcoma virus induced tumors was studied. Neonatal puppies were compared with adolescent dogs. Three different types of cytotoxicity were investigated: complement dependent cytotoxicity, T-cell-mediated cytotoxicity and antibody dependent cellular cytotoxicity. The relationship between the spontaneous regression of the sarcoma and the development of the immune system of the puppies is discussed.
D000818:Animals; D000831:Animals, Newborn; D000920:Antibody-Dependent Cell Cytotoxicity; D003165:Complement System Proteins / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D004285:Dogs; D005253:Sarcoma Viruses, Feline; D012513:Sarcoma, Experimental / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014412:Tumor Virus Infections / Q000276:immunology*
D003165:Complement System Proteins