title: Peroxisomes (microbodies) in human glial tumors. a cytochemical ultrastructural study.
abstract: Morphologically and cytochemically defined peroxisomes (microbodies) were demonstrated in a series of 11 human glial tumors. The cytochemical methods used were diaminobenzidine method for catalase and a tetrazolium salt-phenozine methosulfate method for D-amino-acid oxidase. Ultrastructurally, the peroxisomes were found as single membrane limited organelles with a granular matrix. Marginal plates as well as continuities with the smooth endoplasmic reticulum could be demonstrated. Peroxisomes were found most abundantly in subependymal giant cell astrocytomas, to a lesser number in astrocytomas and least abundantly in glioblastomas.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000201:enzymology / Q000648:ultrastructure; D001932:Brain Neoplasms / Q000201:enzymology / Q000648:ultrastructure*; D002374:Catalase / Q000032:analysis; D003605:D-Amino-Acid Oxidase / Q000032:analysis; D005260:Female; D005910:Glioma / Q000201:enzymology / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008830:Microbodies / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D009940:Organoids / Q000648:ultrastructure*
chemical_list: D002374:Catalase; D003605:D-Amino-Acid Oxidase