Effect of cryptorchidism and orchidopexy on 3B hydroxysteroid dehydrogenase activity in rat testicle.
The activity of 3B hydroxysteroid dehydrogenase (3BHSD), an enzyme intimately involved in the biosynthesis of testosterone, was histochemically examined in cryptorchid testes of the rat and also after subsequent orchidopexy. Enzyme activity was severly depressed in testes held 15 days or longer in the abdominal cavity but promptly returned to normal in testes that were returned to the scrotum. This particular enzyme system was not permanently injured in the rat by the cryptorchid condition up to 40 days.
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D000818:Animals; D003456:Cryptorchidism / Q000201:enzymology* / Q000601:surgery; D008297:Male; D051381:Rats; D013737:Testis / Q000201:enzymology*
D015096:3-Hydroxysteroid Dehydrogenases