[Ion channels formed in bilayer lipid membranes by large subunits of Na,K-ATPase and activated by ATP and p-nitrophenylphosphate].
BLM modified by a large subunit of Na,K-ATPase is capable of forming ATP-dependent channels of conductivity in the presence of Na+ and K+ ions from the reaction medium eliminated the ATP effect, however, in this case the pNPP activated K+-conductivity is observed.
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002463:Cell Membrane Permeability; D004789:Enzyme Activation / Q000187:drug effects; D007473:Ion Channels / Q000378:metabolism*; D008051:Lipid Bilayers / Q000378:metabolism*; D009596:Nitrophenols / Q000494:pharmacology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013379:Substrate Specificity
D007473:Ion Channels; D008051:Lipid Bilayers; D009596:Nitrophenols; D009943:Organophosphorus Compounds; C008644:nitrophenylphosphate; D000255:Adenosine Triphosphate; D000254:Sodium-Potassium-Exchanging ATPase
Ionnye kanaly, obrazuemye v bisloĭnykh lipidnykh membranakh bol'shimi sub''edinitsami Na,K-ATFazy i aktiviruemye ATF i p-nitrofenilfosfatom.