[Effect of vitamin D on lead assimilation].
It was established in experiments on rickety chickens given and not given an additive of 0.5% lead acetate to the diet and vitamin D3 (10 IU/day intramuscularly) for a week that vitamin D induced an appreciable increase of lead deposition in the tissues. The degree of lead poisoning assessed according to the content of delta-aminolevulinic acid in red cells was 8 times as increased as compared with the same indicator in chickens not injected with vitamin D. The balance studies demonstrated that retention of the diet lead under the effect of vitamin D rose 2 times. Vitamin D noticeably stimulated 210Pb absorption from chicken duodenum in experiments in situ.
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D002645:Chickens; D002762:Cholecalciferol / Q000009:adverse effects* / Q000627:therapeutic use; D004386:Duodenum / Q000378:metabolism; D007408:Intestinal Absorption / Q000187:drug effects; D007668:Kidney / Q000378:metabolism; D007854:Lead / Q000378:metabolism*; D007855:Lead Poisoning / Q000209:etiology*; D012279:Rickets / Q000188:drug therapy / Q000378:metabolism*
D002762:Cholecalciferol; D007854:Lead
Vliianie vitamina D na usvoenie svintsa.