title: Study of the intravaginal insert (IVI): acceptability, side effects, and post-coital spermicidal activity.
abstract: The authors describe their experience with a group of 49 sexually active, already protected women in order to evaluate the acceptability, side effects and post-coital spermicidal activity of a new vaginal contraceptive. The intravaginal insert (IVI) consists of a polyester resin plug (sponge) containing a 5% solution of nonoxynol-9 bound in a cold formation process, and having a cotton loop attached to the lower end. The results of this study indicate that this new vaginal contraceptive is free of major side effects, is well accepted by users, and has strong spermicidal and mechanical activity. Future clinical testing in order to try its anti-conceptive effectiveness is warranted.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D003274:Contraceptive Devices, Female / Q000009:adverse effects; D005260:Female; D006801:Humans; D017137:Nonoxynol; D010570:Pessaries; D011092:Polyethylene Glycols / Q000009:adverse effects; D011897:Random Allocation; D012117:Resins, Synthetic; D012959:Socioeconomic Factors; D013089:Spermatocidal Agents / Q000009:adverse effects; D013997:Time Factors
chemical_list: D012117:Resins, Synthetic; D013089:Spermatocidal Agents; D017137:Nonoxynol; D011092:Polyethylene Glycols