[Use of a labeled aerosol in the evaluation of the role of mucociliary transport and coughing in tracheobronchial clearance].
The mucociliary transport system has been found to be an important defense mechanism of the airways. The system is severely damaged in certain acute infections. In chronic bronchitis mucociliary transport is most severely impaired and this impairment is probably directly involved in the pathogenesis of the chronic airways obstruction that may complicate the disease. In hypersecretory states much of the clearance is performed by coughing. Only productive cough is effective in clearing the airways from small particles.
D000208:Acute Disease; D000336:Aerosols; D001980:Bronchi / Q000502:physiology*; D002908:Chronic Disease; D002923:Cilia / Q000502:physiology*; D003371:Cough / Q000503:physiopathology*; D006801:Humans; D009092:Mucous Membrane / Q000502:physiology; D012140:Respiratory Tract Diseases / Q000503:physiopathology; D014132:Trachea / Q000502:physiology*
D000336:Aerosols
Utilisation d'un aérosol marqué dans l'évaluation du role du transport mucociliaire et de la toux dans la clairance trachéobronchique.