title: Estrogenization in women with postmenopausal ovarian hyperthecosis.
abstract: The cases of two women who show postmenopausal bleeding and signs of endogenous estrogen production are presented. At laparotomy, ovarian hyperthecosis was found and confirmed histologically. Determination of 17 beta-estradiol concentrations in ovarian and peripheral veins suggested that these ovaries actively secreted excessive estrogens. Ovarian hyperthecosis is discussed as a cause of renewed endogenous estrogen activity in the postmenopausal women.
mesh_terms: D000368:Aged; D004967:Estrogens / Q000096:biosynthesis; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008593:Menopause; D008875:Middle Aged; D010053:Ovary / Q000378:metabolism; D011127:Polyps / Q000473:pathology; D013799:Theca Cells / Q000473:pathology*; D014592:Uterine Hemorrhage / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology; D014599:Uterus / Q000473:pathology
chemical_list: D004967:Estrogens