Late results after surgical treatment of maldescended testes with special regard to exocrine and endocrine testicular function.
Testicular volumes and exocrine testicular function were determined in 82 men who had undergone orchidopexy (36 bilateral, 46 unilateral) at 5-18 years of age. The testicular volumes in unilateral and bilateral orchdopexied patients correspond to those on normal mature males. Semen analyses in unilateral cryptorchidism were normal in 13, doubtful in 23 and pathological in 10 patients. Out of a total of 36 patients who have undergone bilateral orchidopexy, 3 patients were found to have normal, 7 patients doubtful and 26 patients pathological sperm analyses. Endocrine evaluation in bilateral cryptorchidism (prepuberal, puberal and postpuberal) showed no differences in testosterone levels compared to control groups. Some postpuberal patients with pathological sperm analyses were found to have elevated LH and FSH levels; 22 postpuberal patients with pathological sperm analyses showed hypergonadotropism with markedly elevated LH and FSH levels after GnRH.
D000293:Adolescent; D000328:Adult; D002648:Child; D003456:Cryptorchidism / Q000601:surgery*; D005298:Fertility; D005640:Follicle Stimulating Hormone / Q000097:blood; D005500:Follow-Up Studies; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010906:Pituitary Hormone-Releasing Hormones; D013091:Spermatogenesis; D013094:Spermatozoa / Q000032:analysis; D013737:Testis / Q000033:anatomy & histology; D013739:Testosterone / Q000097:blood
D010906:Pituitary Hormone-Releasing Hormones; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone