title: [Mnemic disturbances following experimental alcohol-tranquilizer application (author's transl)].
abstract: Mnemic disturbances occurred in 8 of 14 subjects during a pharmcopsychological investigation of possible interactions between alcohol and dipotassium chlorazepate (Tranxilium). The blood alcohol concentrations were between 0.87% and 1.32%; the serum concentrations of the active metabolite nordiazepam were in the therapeutic range between 145 ng/ml and 345 ng/ml. The constitutional, dispositional, and situative conditions are presented. The forensic medical interpretation of such mnemic disturbances must be made critically and with reservation when evaluating a psychopathological state.
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000647:Amnesia / Q000139:chemically induced*; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001711:Biotransformation; D003009:Clorazepate Dipotassium / Q000009:adverse effects* / Q000097:blood; D000431:Ethanol / Q000097:blood; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000187:drug effects
chemical_list: D014151:Anti-Anxiety Agents; D000431:Ethanol; D003009:Clorazepate Dipotassium
vernacular_title: Mnestische Störungen nach experimenteller Alkohol-Tranquilizer-Belastung.