title: Parenteral acyclovir therapy for cytomegalovirus infection after renal transplantation.
abstract: Three patients who had received cadaveric renal transplants developed fevers within three months of transplantation. Concurrent cytomegalovirus infection was confirmed by virological studies. In all three patients there was both a clinical and virological response to a five day course of intravenous acyclovir. In one patient the dose required to produce this response was 5 mg/kg/day; however two patients required 10 mg/kg/day. All three patients remain well after 8-12 months follow-up.
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D000328:Adult; D003586:Cytomegalovirus Infections / Q000188:drug therapy* / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007263:Infusions, Parenteral; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy
chemical_list: D000212:Acyclovir