[Use of a manganese citrate complex in the determination of liver enzyme activities in the aging process and following treatment with aminoethylisothiuronium bromide hydrobromide (AET)].
Some oxidation enzyme as well as reductase and dehydrogenases in liver samples were estimated. With the manganese-citrate plus diethylen-p-phenylene-diamine complex method an increases reduction-capacity and succino-dehydrogenase activity was recorded in the liver samples of the 23 month old rat. No differences were found between the 6 and 12 month old rat liver samples. Following a 8-month amino-ethyl-isothiuronium. Br. HBr (AET) treatment (100 mg/kg) of mice both the reduction-capacity and the succino-dehydrogenase activity showed an elevated value in the liver samples of the experimental animals.
D000375:Aging; D000818:Animals; D002951:Citrates; D019343:Citric Acid; D003576:Electron Transport Complex IV / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008345:Manganese; D051379:Mice; D010084:Oxidation-Reduction / Q000187:drug effects; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism; D000338:beta-Aminoethyl Isothiourea / Q000633:toxicity*
D002951:Citrates; D004798:Enzymes; D000338:beta-Aminoethyl Isothiourea; D019343:Citric Acid; D008345:Manganese; D013385:Succinate Dehydrogenase; D003576:Electron Transport Complex IV
Die Anwendung des Manganzitrat-Komplexes in Bestimmung der Enzymaktivitäten der Leber während der Alternsprozesse und nach Behandlung mit Aminoäthylisothiuronium. Br. HBr (AET).