[Attempt to affect hyperlipoproteinemia in patients by long-term anticoagulant therapy].
The antilipidemic drugs potentiate the effect of the indirect anticoagulants and their co-medication is difficult, risky and requires often laboratory checks. That is why the hyperlipoproteinemias were treated with wheat bran in the patients with hyperlipoproteinemia and thrombembolic diseases with anticoagulant therapy. Twenty seven patients, aged from 34 to 71 (average age 44,6 years)--21 males and 6 females were treated. The anticoagulant treatment was conducted with syncumar in 21 and with marcoumar and falithrom in 6 patients. The patients were recommended to take wheat bran in a dose of 15-20 g, three times daily, suspended in liquid foods for the improvement of the tase, in the course of 1 and 1/2 to 2 months after meals. The therapeutic hypocoagulemia remained optimal. The total lipids were reduced with 20,2 per cent, cholesterine--with 23,8 per cent and triglycerols with 25%. The reduction is statistically significant. No complications were observed but light flatulence.
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D004043:Dietary Fiber / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006951:Hyperlipoproteinemias / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D013997:Time Factors; D014908:Triticum
D000925:Anticoagulants; D004043:Dietary Fiber; D000960:Hypolipidemic Agents; D008055:Lipids
Opit za povliiavane na khiperlipoproteinemiia pri bolni na prodŭlzhitelna antikoagulantna terapiia.