title: Timolol in the therapy of "ocular hypertension".
abstract: Timolol has been shown to be at least as effective as pilocarpine and epinephrine in the therapy of open angle glaucoma. To date there appear to have been few serious side effects from timolol when it has been used in patients without cardiac or pulmonary disease. The decision whether and when to treat a patient with elevated intraocular pressure depends upon a weighing of risk of glaucoma damage versus the side effects of the drugs used in therapy. The use of the beta blocking agents, particularly timolol, in the therapy of ocular hypertension is considered. Reports on the efficacy and safety of timolol are cited, and the author's reevaluation of their own series of patients treated with timolol for 17-36 months is discussed.
mesh_terms: D000319:Adrenergic beta-Antagonists; D001665:Binding Sites / Q000187:drug effects; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D011412:Propanolamines / Q000627:therapeutic use*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects; D013999:Timolol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; D011943:Receptors, Adrenergic, beta; D013999:Timolol