title: Sweat gland carcinoma of the hand: two cases of malignant eccrine spiradenoma.
abstract: Two cases of malignant eccrine spiradenoma of the hand are reported. This malignancy is potentially fatal and is believed to arise from preexisting, long-standing benign spiradenomas. These rare tumors should be considered in the hand surgeon's evaluation and management of any long-standing undiagnosed tumor of the hand. Benign spiradenomas should be excised completely and the patient followed carefully. Location and grade of established malignant tumors should dictate therapy.
mesh_terms: D006607:Adenoma, Sweat Gland / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D005385:Fingers / Q000601:surgery; D006225:Hand; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000473:pathology / Q000601:surgery*