In vitro characterization of adrenergic receptors mediating extrusion of preformed sebum from preputial gland of rat.
Extrusion of preformed sebum from the preputial glands of rat after phenylephrine and adrenaline treatment, and its inhibition by alpha-receptor blocking agents under in vitro conditions, shows that secretory response of the glands is influenced by alpha-adrenergic receptors, and isoproterenol--a beta-agonist--is not effective in elicitation of exudation of secretion from the preputial gland.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D010413:Penis / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D011941:Receptors, Adrenergic / Q000494:pharmacology*; D011942:Receptors, Adrenergic, alpha / Q000494:pharmacology*; D012629:Sebum / Q000378:metabolism*
D000316:Adrenergic alpha-Agonists; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D007545:Isoproterenol