Diminished bacterial defences with intralipid.
'Intralipid', a lipid emulsion used in parenteral nutrition, impaired bacterial clearance and enhanced bacterial virulence in mice. In addition it inhibited the chemotaxis of human neutrophils in vitro. Intralipid may enhance the risk of bacterial sepsis in certain patients.
D000818:Animals; D001419:Bacteria / Q000276:immunology*; D001424:Bacterial Infections / Q000209:etiology; D002634:Chemotaxis, Leukocyte; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects*; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains / Q000276:immunology; D012157:Mononuclear Phagocyte System; D009504:Neutrophils / Q000276:immunology; D009748:Nutrition Disorders / Q000628:therapy; D012306:Risk; D018805:Sepsis / Q000209:etiology*; D013290:Streptococcal Infections / Q000276:immunology; D013292:Streptococcus agalactiae; D014774:Virulence
D005217:Fat Emulsions, Intravenous