Transient kinetics of an inward rectifier K+ channel in the myocardial cell membrane.
The current through a myocardial inward rectifier K+ channel was recorded by the patch clamp technique. The inactivation gate of the channel has open probability of nearly 1 at the potentials positive to EK and showed peculiar kinetics in the 1st open events after hyperpolarization from these potentials. Analysis of this kinetics suggested two open states in this gate.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D004553:Electric Conductivity; D006168:Guinea Pigs; D006706:Homeostasis; D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008564:Membrane Potentials; D008954:Models, Biological; D009206:Myocardium / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*
D007473:Ion Channels; D011188:Potassium