Pseudomembranous colitis. A complication of sulfasalazine therapy in a patient with Crohn's colitis.
Pseudomembranous colitis is a potentially life-threatening acute medical problem usually associated with a history of previous antibiotic exposure. Presented here is a case of sulfasalazine associated pseudomembranous colitis in a patient with known Crohn's colitis. The diagnosis was confirmed by identifying Clostridium difficile toxin in the stool. This a newly reported complication of sulfasalazine therapy.
D000328:Adult; D003424:Crohn Disease / Q000188:drug therapy*; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D012460:Sulfasalazine / Q000009:adverse effects*
D012460:Sulfasalazine