title: [Seasonal changes in the blood coagulating and anticoagulating system indices in men at the preclinical stage of ischemic heart disease].
abstract: Examination of 52 males (aged 23 to 40 years) in the preclinical stage of ischemic heart disease revealed seasonal differences in the values of the blood coagulation and anticoagulation systems: in the spring, there was an increase in blood coagulation activity displayed by growth of the concentration of fibrinogen and soluble fibrin and a reduction in the amount of the plasminogen activator. The authors suggest conducting preventive treatment of patients in the spring, the most unfavourable season in respect of the effect of the pathogenetic factors.
mesh_terms: D000328:Adult; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D003327:Coronary Disease / Q000503:physiopathology*; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D005222:Mental Fatigue / Q000503:physiopathology; D012306:Risk; D012621:Seasons; D013315:Stress, Psychological / Q000503:physiopathology
vernacular_title: Sezonnye izmeneniia pokazateleĭ svertyvaiushcheĭ i protivosverty-vaiushcheĭ sistem krovi u muzhchin v doklinicheskoĭ stadii ishemicheskoĭ bolezni miokarda.