title: Auditing hospital drug utilisation by means of defined daily doses per bed-day. A methodological study.
abstract: The utilisation of hypnotics, sedatives, and minor tranquillisers (HSmT) was studied by means of drug-delivery and hospital occupancy statistics for 1975-1977 in a Swedish university hospital. A total of 0.53 so-called defined daily doses (DDD)/bed-day were delivered in 1975, implying that every second patient might have regularly been prescribed HSmT. The benzodiazepines were predominant with 71% of the deliveries. Five major drugs accounted for 88%. The drug pattern and the range of DDD/day-bed (0.09-1.18) differed considerably between the departments. Drugs not recommended by the hospital's Pharmacy and Therapeutics Committe accounted only for 3% of deliveries. In a drug surveillance study performed in two medical wards, HSmT were prescribed for 43% of 274 patients. Drug delivery and prescription data were in broad agreement. Drug information activities in the hospital had a clearly discernable influence on the delivered DDD/bed-day. This measure is an inexpensive indicator of drug utilisation in a hospital and a suitable basis for therapeutic audit.
mesh_terms: D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D011307:Drug Prescriptions; D004363:Drug Utilization / Q000639:trends*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008510:Medication Systems, Hospital; D013548:Sweden; D014600:Utilization Review / Q000379:methods*
chemical_list: D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives