[Histological structure of the primary tumor and status of the regional lymph nodes in breast cancer].
In 170 primary invasive carcinomas of the breast, morphological criteria of the primary tumour--tumour size, WHO classification, malignancy according to Bloom, number and status of foci, lymphangiosis carcinomatosa, stroma reaction--were compared with the axillary lymph node status. In addition, the numbers of resected lymph nodes of metastasised and non-metastasised carcinomas were compared, taking into consideration the number of affected lymph nodes. In patients with more than three affected lymph nodes there were significantly more resected lymph nodes. It is possible that the degree of metastasising exercises an influence on the size of the lymph nodes and hence on the likelihood of their being detected in the axillary fatty connective tissue. The importance of histological structural classification of the primary tumour (WHO) and of the tumour size, for metastasising into the axillary lymph nodes, was confirmed. No significant correlation was found between prognostically relevant tumour criteria on the one hand, and the qualitative proof of metastases in the axillary lymph nodes on the other. Particularly in cases without established involvement of the lymph nodes, it will be necessary to take into account relevant structural criteria of the primary tumour when planning an appropriate therapy.
D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged
Untersuchungen zur histologischen Struktur des Primärtumors und zum Status der regionalen Lymphknoten beim Mammakarzinom.