Interaction of cardiac glycosides with (Na+ + K+)-activated ATPase. A biochemical link to digitalis-induced inotropy.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002301:Cardiac Glycosides / Q000378:metabolism* / Q000494:pharmacology; D004070:Digitalis; D006801:Humans; D007700:Kinetics; D008024:Ligands; D008274:Magnesium / Q000494:pharmacology; D009200:Myocardial Contraction / Q000187:drug effects*; D010042:Ouabain / Q000378:metabolism / Q000494:pharmacology; D010946:Plants, Medicinal; D010947:Plants, Toxic; D011188:Potassium / Q000494:pharmacology; D011487:Protein Conformation; D011955:Receptors, Drug / Q000032:analysis; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000032:analysis / Q000378:metabolism*; D014638:Vanadates; D014639:Vanadium / Q000378:metabolism
D002301:Cardiac Glycosides; D008024:Ligands; D011955:Receptors, Drug; C028996:cardiac glycoside receptors; D014639:Vanadium; D014638:Vanadates; D010042:Ouabain; D000255:Adenosine Triphosphate; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D008274:Magnesium; D011188:Potassium