title: Phenacein--an angiotensin-converting enzyme inhibitor produced by a streptomycete. II. Isolation, structure determination and synthesis.
abstract: Phenacein, an inhibitor of angiotensin-converting enzyme, has been isolated from the fermentation broth of a Streptomyces species belonging to the Streptomyces tanashiensis-zaomyceticus group. The inhibitor was shown to be 3,6-dihydroxy-1-phenazinecarboxylic acid by spectroscopic, degradative and synthetic methods.
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors; D055598:Chemical Phenomena; D002621:Chemistry; D010619:Phenazines / Q000138:chemical synthesis / Q000302:isolation & purification*; D013302:Streptomyces / Q000378:metabolism
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D010619:Phenazines; C043271:phenacein