[Single dose treatment of primary syphilis with Benzathine penicillin (author's transl)].
Out of 40 male patients with primary syphilis diagnosed microscopically by dark field preparations and by serological tests 20 patients were treated with a single intramuscular injection of 4.8 millions I. U. Benzathine penicillin and 20 patients with a daily intramuscular injection of 1 million I. U. Clemizol penicillin over a period of 21 days. In all patients success of treatment was verified by complete remission of the clinical symptoms and by serological tests over a period of 2 years. Single dose treatment with Benzathine penicillin represents a simple and reliable method of treatment of primary syphilis.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents; D001562:Benzimidazoles / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D004338:Drug Combinations / Q000627:therapeutic use; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010400:Penicillin G / Q000627:therapeutic use; D010401:Penicillin G Benzathine / Q000627:therapeutic use*; D012189:Retrospective Studies; D013587:Syphilis / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D003692:Delayed-Action Preparations; D004338:Drug Combinations; C030906:clemizolpenicillin; D010400:Penicillin G; D010401:Penicillin G Benzathine
Einzeitbehandlung der primären Syphilis mit Benzathin-Penicillin. Eine retrospektive Studie.