[Detection of papillomavirus capsid antigens and human papillomavirus 16-related DNA in Bowenoid papulosis and Bowen disease].
In one out of 22 cases of histologically diagnosed bowenoid papulosis, we could detect human papilloma virus (HPV) capsid antigen in paraffin sections fixed with formalin by means of the peroxidase-antiperoxidase (PAP) test; there were no positive findings regarding biopsies taken from Bowen's disease. Southern blot hybridization technique revealed HPV 16 DNA in 8 out of 10 cases of bowenoid papulosis; there was one positive identification out of 5 cases of Bowen's disease.
D000328:Adult; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D001913:Bowen's Disease / Q000276:immunology*; D002213:Capsid / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D003218:Condylomata Acuminata / Q000276:immunology; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005833:Genital Neoplasms, Female / Q000276:immunology; D005834:Genital Neoplasms, Male / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D027383:Papillomaviridae / Q000276:immunology; D012878:Skin Neoplasms / Q000276:immunology*; D014412:Tumor Virus Infections / Q000276:immunology*
D000956:Antigens, Viral; D004279:DNA, Viral
Nachweis von Papillomvirus Capsidantigenen und Human Papillomvirus (HPV) 16 verwandter DNS in Bowenoider Papulose und Morbus Bowen.