title: Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite.
abstract: A delta 9-THC metabolite has been identified in human urine as an ester linked glucuronide of delta 9-THC-11-oic acid. Its identity was established by a comparison of mass spectra from the metabolite extracted from human urine and synthetically prepared material. delta 9-THC-11-oic acid glucuronide was found to be responsible for the major part of RIA cross-reactivity in urine with the Guildhay cannabinoid antiserum used in this study.
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000652:urine; D005965:Glucuronates / Q000652:urine; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D013058:Mass Spectrometry; D011817:Rabbits; D011863:Radioimmunoassay
chemical_list: D005965:Glucuronates; C026502:delta(9)-tetrahydrocannabinol-11-oic acid glucuronide; D013759:Dronabinol; D005966:Glucuronidase