title: Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.
abstract: Five patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares. Low levels of pressure (range 4.5-10 cm H2O) completely prevented upper airway occlusion during sleep in each patient and allowed an entire night of uninterrupted sleep. Continuous positive airway pressure applied in this manner provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructive sleep apnoea syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D000402:Airway Obstruction / Q000517:prevention & control*; D002245:Carbon Dioxide / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D009666:Nose; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000295:instrumentation / Q000379:methods*; D012119:Respiration; D012890:Sleep; D012891:Sleep Apnea Syndromes / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D006454:Hemoglobins; D002245:Carbon Dioxide; D010100:Oxygen