Ipecac-induced myopathy simulating dermatomyositis.
We studied a young woman with an eating disorder. To induce vomiting, she took syrup of ipecac daily for 2 years, and then developed insidious, progressive muscle weakness. Skin findings were similar to those of dermatomyositis. Muscle biopsy, however, was similar to experimental emetine myopathy and lacked inflammatory features. Upon cessation of ipecac abuse, strength returned. We believe that this patient had ipecac-induced muscle weakness.
D000328:Adult; D001706:Biopsy; D003882:Dermatomyositis / Q000139:chemically induced* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007486:Ipecac / Q000009:adverse effects*; D009132:Muscles / Q000473:pathology; D009468:Neuromuscular Diseases / Q000139:chemically induced* / Q000473:pathology
D007486:Ipecac