title: Rhodopsin kinase activity in the mammalian pineal gland and other tissues.
abstract: Rhodopsin kinase, an enzyme involved in photochemical transduction in the retina, has been found in the mammalian pineal gland in amounts equal to those in the retina; other tissues had 7 percent of this amount, or less. This finding suggests that, in mammals, rhodopsin kinase functions in the pineal gland and other tissues to phosphorylate rhodopsin-like integral membrane receptors and is thereby involved in signal transduction.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D005136:Eye Proteins; D051606:G-Protein-Coupled Receptor Kinase 1; D008027:Light; D008168:Lung / Q000201:enzymology; D010766:Phosphorylation; D010870:Pineal Gland / Q000201:enzymology*; D010902:Pituitary Gland / Q000201:enzymology; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000378:metabolism; D012160:Retina / Q000201:enzymology; D014018:Tissue Distribution; D015032:Zinc / Q000494:pharmacology
chemical_list: D005136:Eye Proteins; D047428:Protein Kinase Inhibitors; D011943:Receptors, Adrenergic, beta; D011494:Protein Kinases; D051606:G-Protein-Coupled Receptor Kinase 1; C496765:Grk1 protein, rat; D015032:Zinc