title: Opiate-mediated control of luteinizing hormone in the male: role in the development of narcotic tolerance and physical dependence.
mesh_terms: D000700:Analgesics; D000818:Animals; D001921:Brain / Q000378:metabolism; D002369:Castration; D005405:D-Ala(2),MePhe(4),Met(0)-ol-enkephalin / Q000494:pharmacology; D004361:Drug Tolerance; D004723:Endorphins / Q000502:physiology; D007987:Gonadotropin-Releasing Hormone / Q000502:physiology; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male; D009021:Morphine Dependence / Q000378:metabolism; D009270:Naloxone / Q000494:pharmacology; D009294:Narcotics / Q000494:pharmacology*; D009293:Opioid-Related Disorders / Q000378:metabolism*; D011957:Receptors, Opioid / Q000187:drug effects; D017473:Receptors, Opioid, kappa; D017450:Receptors, Opioid, mu; D017480:Receptors, sigma; D013375:Substance Withdrawal Syndrome / Q000139:chemically induced / Q000378:metabolism; D013737:Testis / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000700:Analgesics; D004723:Endorphins; D009294:Narcotics; D011957:Receptors, Opioid; D017473:Receptors, Opioid, kappa; D017450:Receptors, Opioid, mu; D017480:Receptors, sigma; D007987:Gonadotropin-Releasing Hormone; D009270:Naloxone; D013739:Testosterone; D005405:D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; D007986:Luteinizing Hormone