title: Comparison between the properties of the vagal and splanchnic glucoreceptors of the small intestine. Involvement in insulin release.
abstract: It was recently well established that the vagal intestinal glucoreceptors are involved in insulin release. In this work we demonstrate that the splanchnic glucoreceptors play a unique role in insulin release: their activation induces a decrease, like strong mechanical stimulation. The physiological meaning of this effect is not clear, it may be a non-physiological response, because high glucose concentration is abnormal in the jejuno-ileal lumen. This work represents the first comparison between the properties and role of different kinds of glucoreceptors.
mesh_terms: D000818:Animals; D002415:Cats; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007421:Intestine, Small / Q000294:innervation*; D007515:Islets of Langerhans / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D011956:Receptors, Cell Surface / Q000502:physiology*; D013153:Splanchnic Nerves / Q000502:physiology*; D014630:Vagus Nerve / Q000502:physiology*
chemical_list: D007328:Insulin; D011956:Receptors, Cell Surface; C027786:glucose receptor