Evidence for separation of anesthetic activity from prototypic phencyclidine action in drug discrimination by molecular modification of dioxadrol, a phencyclidine-like dissociative anesthetic.
D000777:Anesthetics; D000818:Animals; D001496:Batrachotoxins / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D004148:Dioxolanes / Q000494:pharmacology*; D004149:Dioxoles / Q000494:pharmacology*; D004193:Discrimination Learning / Q000187:drug effects; D006801:Humans; D008253:Macaca mulatta; D010622:Phencyclidine / Q000378:metabolism; D010880:Piperidines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D017478:Receptors, Phencyclidine
D000777:Anesthetics; D001496:Batrachotoxins; D004148:Dioxolanes; D004149:Dioxoles; D010880:Piperidines; D017981:Receptors, Neurotransmitter; D017478:Receptors, Phencyclidine; C005840:dioxadrol; D010622:Phencyclidine