Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.
Five patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares. Low levels of pressure (range 4.5-10 cm H2O) completely prevented upper airway occlusion during sleep in each patient and allowed an entire night of uninterrupted sleep. Continuous positive airway pressure applied in this manner provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructive sleep apnoea syndrome.
D000293:Adolescent; D000328:Adult; D000402:Airway Obstruction / Q000517:prevention & control*; D002245:Carbon Dioxide / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D009666:Nose; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000295:instrumentation / Q000379:methods*; D012119:Respiration; D012890:Sleep; D012891:Sleep Apnea Syndromes / Q000517:prevention & control*; D013997:Time Factors
D006454:Hemoglobins; D002245:Carbon Dioxide; D010100:Oxygen