The effects of epinephrine, norepinephrine, and phenylephrine on the types of proteins secreted by rat salivary glands.
The types of proteins secreted by rat submandibular glands in response to secretory stimulation with epinephrine, norepinephrine, or phenylephrine were dose-dependent. At relatively high doses the proteins secreted were characteristic of alpha-adrenergic stimulation, whereas at low doses they were characteristic of beta-adrenergic stimulation.
D000316:Adrenergic alpha-Agonists; D000318:Adrenergic beta-Agonists; D000818:Animals; D002395:Catecholamines / Q000600:supply & distribution; D004837:Epinephrine / Q000494:pharmacology*; D009638:Norepinephrine / Q000494:pharmacology*; D010656:Phenylephrine / Q000494:pharmacology*; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects; D011943:Receptors, Adrenergic, beta / Q000187:drug effects; D012469:Salivary Glands / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000378:metabolism*
D000316:Adrenergic alpha-Agonists; D000318:Adrenergic beta-Agonists; D002395:Catecholamines; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D012471:Salivary Proteins and Peptides; D010656:Phenylephrine; D009638:Norepinephrine; D004837:Epinephrine