[Further examinations of the influence of somatostatin on triglyceride absorption (author's transl)].
7 healthy subjects received an oral fat load containing 100 g neutral fat on two test days. The test meal was followed by an infusion of somatostatin (500 micrograms/h) over three hours. On the first test day 150,000 E of an active fungal lipase (extracted from Rhizopus arrhizus) were given with the fat meal. On the second day placebo capsules were administered instead of lipase. No postprandial increase of serum triglyceride levels could be found in both examinations. These results suggest, that the influence of somatostatin on triglyceride absorption cannot be due to the inhibition of pancreatic lipase secretion.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D004041:Dietary Fats / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008049:Lipase / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D013004:Somatostatin / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood*
D001786:Blood Glucose; D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D014280:Triglycerides; D013004:Somatostatin; D002784:Cholesterol; D008049:Lipase
Weitere Untersuchungen zur Frage der Somatostatin-Wirkung auf die Triglyzeridresorption.