Increased adrenergic projection from the locus coeruleus to the lateral geniculate nucleus of rats following one-eye-removal at birth.
Electrophysiological studies were made on plastic changes in the projection from the locus coeruleus (LC) to the lateral geniculate nucleus (LGN). In adult rats with one eye removed at birth it was found that the chance for encountering LC neurons activated antidromically from the LGN was significantly larger in the side of eye removal than in control. This was thought to indicate that the amount of projection from the LC to the LGN had increased in response to eye removal at birth.
D000320:Adrenergic Fibers / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn; D005131:Eye Injuries / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D005829:Geniculate Bodies / Q000473:pathology* / Q000503:physiopathology; D008125:Locus Coeruleus / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D009473:Neuronal Plasticity; D051381:Rats; D011919:Rats, Inbred Strains; D009435:Synaptic Transmission