Age-related changes in bone in the dog: fluid spaces and their potassium content.
We measured erythrocyte, plasma, osteocyte, extravascular extracellular, and total water fluid spaces and calculated their K content in cortical bone of dogs of various age. Total and exchangeable K were measured by atomic absorption spectroscopy and by volume of distribution techniques, respectively. All fluid spaces in bone decreased with increasing age of the dogs. The total and exchangeable K contents of cortical bone and the K content calculated from the fluid spaces were within the same range in each age group. These values all fell with increasing age.
D000375:Aging; D000818:Animals; D001826:Body Fluids / Q000032:analysis*; D001842:Bone and Bones / Q000032:analysis* / Q000502:physiology; D004285:Dogs / Q000502:physiology*; D004912:Erythrocytes; D005110:Extracellular Space / Q000032:analysis; D005260:Female; D008297:Male; D010011:Osteocytes / Q000032:analysis; D011188:Potassium / Q000032:analysis*; D013670:Sodium Pertechnetate Tc 99m; D013057:Spectrum Analysis; D014965:X-Rays
D013670:Sodium Pertechnetate Tc 99m; D011188:Potassium