[First appearance of penicillinase-producing gonococci at Bremen (author's transl)].
Three cases of penicillin-resistant gonorrhoea were detected at Bremen during a period of 3 months: in a tourist and 2 sailors. The infections had been acquired in Thailand, Africa, and USA, respectively. In all 3 cases penicillinase-producing strains of gonococci were isolated, resistant to penicillin in concentrations of 20 micrograms/ml and more. Patients were successfully treated with spectinomycin. The identification of penicillinase-producing strains of gonococci is of major epidemiological importance. Therefore, bacteriological investigations including sensitivity tests and, if necessary, penicillinase-tests should be done in each case of penicillin-resistant gonorrhoea. Relevant cases should be reported to the Venereal Diseases and Treponematoses Unit at Geneva, Switzerland.
D000328:Adult; D001562:Benzimidazoles / Q000627:therapeutic use; D005860:Germany, West; D006069:Gonorrhea / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000201:enzymology; D010400:Penicillin G / Q000627:therapeutic use; D010403:Penicillin Resistance; D010405:Penicillinase / Q000378:metabolism*; D001618:beta-Lactamases / Q000378:metabolism*
D001562:Benzimidazoles; D010405:Penicillinase; D001618:beta-Lactamases; D010400:Penicillin G
Erstmaliges Auftreten penicillinasebildender Gonokokken in Bremen.