title: [Morphological effects of weightlessness and their pathogenesis].
abstract: The paper summarizes the results of morphological and histochemical investigations of rats flown onboard the Soviet biological satellites of the Cosmos series. The changes in different functional systems and organs have been found to be related. The paper contains hypotheses concerning the pathogenesis of the changes detected. It is emphasized that most changes are induced by a reduction of load upon the musculoskeletal system in weightlessness.
mesh_terms: D000222:Adaptation, Physiological; D000307:Adrenal Gland Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D000337:Aerospace Medicine; D000818:Animals; D001847:Bone Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D006651:Histocytochemistry; D006706:Homeostasis; D008854:Microscopy, Electron; D009133:Muscular Atrophy / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D009135:Muscular Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D051381:Rats; D012106:Research; D014893:Weightlessness / Q000009:adverse effects*
vernacular_title: Morfologicheskie éffekty nevesomosti i ikh patogenez.