title: [Hyper-immunoglobulin-prophylaxis and follow-up in vertical hepatitis B (author's transl)].
abstract: The vertical transmission of hepatitis-B virus from chronic HBsAg carrier mothers can cause acute even fatal hepatitis-B, or a chronic HBsAg carrier state in childhood. To prevent this vertical transmission, hepatitis-B- immunoglobulin (HB Ig) is applicated. Frequency and dosis-data are still confusing. Six children were passively immunized with HB Ig according to our schedule. Their serum was controlled for HBsAg and HBsAb with the RIA-method. None of these children became HBsAg positive.
mesh_terms: D002585:Cesarean Section; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage / Q000627:therapeutic use*; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control*; D011247:Pregnancy; D013997:Time Factors
chemical_list: D006514:Hepatitis B Surface Antigens; D007136:Immunoglobulins
vernacular_title: Prophylaxe der vertikalen Hepatitis B durch Hyperimmun-Gammaglobulin. Verlaufskontrollen.