Cimetidine reduction of tumour formation in mice.
Cimetidine, a histamine type-2 receptor antagonist, had a protective effect in mice challenged with cells from two different syngeneic tumours. The results are a further indication of cimetidine's potential as an immunostimulator.
D000818:Animals; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D005354:Fibrosarcoma / Q000188:drug therapy; D006146:Guanidines / Q000627:therapeutic use*; D007167:Immunotherapy; D008214:Lymphocytes / Q000187:drug effects; D008223:Lymphoma / Q000188:drug therapy; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000188:drug therapy* / Q000276:immunology
D006146:Guanidines; D002927:Cimetidine