[Current concept of diagnosis and therapy of acute pancreatitis (author's transl)].
Acute pancreatitis cannnot be diagnosed only by a single sign, symptom or laboratory determination, but on the basis of several clinical and biochemical findings. X-ray examinations and sonography are of limited diagnostic value in the initial phase. --Prognostic signs are helpful in the early evaluation of the course of the disease. --Intensive care in the initial stage is a decisive principle for adequate therapy. --The effect of hormonal and non-hormonal inhibition of pancreatic secretion or enzyme inhibition has not been proven sufficiently until now or has already been shown to be uneffective in controlled studies. --In contrast, albumin-, fluid- and electrolyte-replacement as well as pain relief and nasogastric suction in case of ileus are safe therapeutical procedures. --Besides shock renal and respiratory insufficiency are the most feared complications in acute pancreatitis and require early peritoneal dialysis and artificial ventilation including positive end expiratory pressure.
D000208:Acute Disease; D058186:Acute Kidney Injury / Q000209:etiology; D000700:Analgesics / Q000627:therapeutic use; D000818:Animals; D000863:Antacids / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005934:Glucagon / Q000627:therapeutic use; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D007362:Intensive Care Units; D010195:Pancreatitis / Q000175:diagnosis* / Q000628:therapy; D010530:Peritoneal Dialysis; D011175:Positive-Pressure Respiration; D051381:Rats; D012131:Respiratory Insufficiency / Q000209:etiology; D012769:Shock / Q000209:etiology; D013004:Somatostatin / Q000627:therapeutic use
D000700:Analgesics; D000863:Antacids; D000900:Anti-Bacterial Agents; D013004:Somatostatin; D005934:Glucagon; D007213:Indomethacin
Aktueller Stand von Diagnostik und Therapie der akuten Pankreatitis.