title: Gas chromatographic determination of bromo and fluoro derivatives of benzodiazepine in human body fluids.
abstract: A rapid, sensitive and accurate method for the determination of bromazepam and flunitrazepam in plasma and urine using gas chromatography has been developed. Bromazepam was extracted with diethyl ether and flunitrazepam with hexane at pH 7. A nitrogen detector was used to determine bromazepam and an electron-capture detector was used for flunitrazepam.
mesh_terms: D014151:Anti-Anxiety Agents / Q000097:blood* / Q000652:urine*; D001960:Bromazepam / Q000097:blood* / Q000302:isolation & purification / Q000652:urine*; D002849:Chromatography, Gas / Q000379:methods; D005445:Flunitrazepam / Q000097:blood* / Q000302:isolation & purification / Q000652:urine*; D006801:Humans
chemical_list: D014151:Anti-Anxiety Agents; D005445:Flunitrazepam; D001960:Bromazepam