title: [Paradoxical reactions and interactions of psychopharmaca in children and adolescents (author's transl)].
abstract: After a discussion of the various basic problems concerning the application of psychopharmacological drugs in children and adolescents, paradoxical reactions and interactions of some psychopharmaca are considered. Stimulantia can especially cause disturbances of growth and as a paradoxial reaction the increase of hypermotoric behaviour. Neuroleptics may lead to tardive dyskinesia, to interactions with hypotensors and occasionally to epileptic seizures. As to tricyclic antidepressive it is known that they can cause interactions with hypotensors and thyroid hormones, as well as paradoxical aggressive reactions. In connection with tranquilizers paradoxical reactions as anxiety and agitation as well as the so-called paradoxical rage reaction could be observed. Combinations of antiepileptica and psychopharmaca should only be used if there is no other possibility for adequate treatment. After all, the field of indications of psychopharmacological drugs in children and adolescents seems to be rather narrow.
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D001569:Benzodiazepines / Q000009:adverse effects; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D002648:Child; D004347:Drug Interactions; D006130:Growth Disorders / Q000139:chemically induced; D006801:Humans; D008094:Lithium / Q000009:adverse effects; D009069:Movement Disorders / Q000139:chemically induced; D011619:Psychotropic Drugs / Q000009:adverse effects* / Q000378:metabolism
chemical_list: D000927:Anticonvulsants; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D000697:Central Nervous System Stimulants; D011619:Psychotropic Drugs; D001569:Benzodiazepines; D008094:Lithium
vernacular_title: Paradoxe Reaktionen und Interaktionen von Psychopharmaka bei Kindern und Jugendlichen.