title: Counterarguments against alleged proof of the NA-K pump in studies of K+ and Na+ distributions in amphibian eggs.
abstract: With the aid of an ingenious technique called the reference phase method, Horowitz and his coworkers tested the alternative theories of solute distribution in living cells. Many interesting and significant findings were reported. However, a careful study of their papers led me to the belief that their claim of a proof for the Na pump theory was unwarranted. By taking into account other relevant information in the literature one can argue that their data in fact support an alternative hypothesis, the association-induction hypothesis.
mesh_terms: D000327:Adsorption; D000663:Amphibians; D000818:Animals; D001693:Biological Transport, Active; D002451:Cell Compartmentation; D004566:Electrodes; D005260:Female; D005780:Gelatin; D007413:Intestinal Mucosa / Q000502:physiology; D009132:Muscles / Q000502:physiology; D010063:Ovum / Q000502:physiology*; D011188:Potassium / Q000502:physiology*; D012964:Sodium / Q000502:physiology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology*
chemical_list: D005780:Gelatin; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium