The anesthetized guinea pig as a versatile pharmacological test object.
An anesthetized animal preparation suitable for testing the pharmacological properties of a variety of potentially effective new compounds is described. The advantage of such a procedure as an useful tool to determine the pharmacodynamic profile of the new agents is described in detail.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000758:Anesthesia; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005260:Female; D006168:Guinea Pigs / Q000502:physiology*; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D010276:Parasympatholytics / Q000494:pharmacology
D000319:Adrenergic beta-Antagonists; D000893:Anti-Inflammatory Agents; D006634:Histamine H1 Antagonists; D010276:Parasympatholytics