Detection and immunochemical characterization of a primate type C retrovirus-related p30 protein in normal human placentas.
We find that 12 of 14 specimens of normal human term placentas analyzed by one- or two-dimensional electrophoresis and immunoblotting contain a protein or polypeptide of approximately equal to 30,000 daltons that is antigenically cross-reactive with p30 core protein of the simian sarcoma-associated virus/gibbon ape leukemia virus primate retrovirus group and is physicochemically similar to reference murine and primate type C retrovirus p30s. This finding may lead to an understanding of endogenous type C retrovirus gene expression in humans.
D000914:Antibodies, Viral; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007526:Isoelectric Point; D008970:Molecular Weight; D010920:Placenta / Q000382:microbiology*; D011247:Pregnancy; D012190:Retroviridae / Q000032:analysis* / Q000276:immunology; D014764:Viral Proteins / Q000032:analysis* / Q000276:immunology
D000914:Antibodies, Viral; D014764:Viral Proteins