[Fatal polyarteritis nodosa following Graves' disease (author's transl)].
Polyarteritis nodosa (PAN), with a fatal outcome, developed during the course of a therapeutically controlled Graves'disease. A review of the published literature confirms that two mechanisms may be involved in the onset of PAN in hyperthyroid patients: an immune response, which is probable in the case reported, or a toxic effect related to the treatment of the hyperthyroidism. This case also emphasizes the therapeutical difficulties encountered, in spite of the corticoid and cyclophosphamide associated treatment with plasmapheresis.
D000293:Adolescent; D002231:Carbimazole / Q000009:adverse effects; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D010488:Polyarteritis Nodosa / Q000139:chemically induced / Q000209:etiology* / Q000276:immunology
D002231:Carbimazole
Périartérite noueuse mortelle au décours d'une maladie de Basedow.