Hexose metabolism in pancreatic islets: phosphoglycerate 2,3-mutase and enolase activities in rat islets.
Rat islet homogenates display both phosphoglycerate 2,3-mutase and enolase activities. When phosphoglycerate 2,3-mutase is activated by 2,3-diphosphoglycerate, the reaction velocity becomes close to that of enolase. The islet content in 2,3-diphosphoglycerate is sufficiently high to allow virtually full activation of phosphoglycerate 2,3-mutase.
D019794:2,3-Diphosphoglycerate; D000818:Animals; D004163:Diphosphoglyceric Acids / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D005988:Glyceric Acids / Q000378:metabolism; D006601:Hexoses / Q000378:metabolism*; D007515:Islets of Langerhans / Q000201:enzymology*; D010736:Phosphoglycerate Mutase / Q000378:metabolism*; D010751:Phosphopyruvate Hydratase / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D051381:Rats
D004163:Diphosphoglyceric Acids; D005988:Glyceric Acids; D006601:Hexoses; D019794:2,3-Diphosphoglycerate; C008885:2-phosphoglycerate; C005156:3-phosphoglycerate; D010770:Phosphotransferases; D010751:Phosphopyruvate Hydratase; D010736:Phosphoglycerate Mutase