title: Distribution of somatostatin in the frog brain, Rana catesbiana, in relation to location of catecholamine-containing neuron system.
abstract: The distribution of somatostatin (SRIF)-immunoreactive structures in the central nervous system of the bull frog (both with and without treatment of colchicine) was studied, using the indirect immunofluorescence technique of Coons and co-workers (Coons, '58). SRIF-containing cells were observed in more than ten areas including the spinal cord. These SRIF-positive cells showed segmental distribution, in that SRIF-positive neurons were identified in various areas at various brain levels. An extensive network of SRIF-positive fibers was found in most parts of the central nervous system. The distribution of a catecholamine (CA)-containing neuron system in the frog brain is also presented in this study. The possible interactions between SRIF and CA neurons systems are briefly discussed.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism*; D004027:Diencephalon / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D006624:Hippocampus / Q000378:metabolism; D006801:Humans; D008297:Male; D009474:Neurons / Q000378:metabolism; D009830:Olfactory Bulb / Q000378:metabolism; D011892:Rana catesbeiana / Q000378:metabolism*; D013004:Somatostatin / Q000378:metabolism*; D013116:Spinal Cord / Q000378:metabolism
chemical_list: D002395:Catecholamines; D013004:Somatostatin