[Acute viral hepatitis and hepatitis B virus markers in chronic liver disease and primary cancer of the liver].
A clinical and etiological study of 171 cases of acute hepatitis in subjects over 15 years of age showed that 73.7% were of the B type and 25.7% of the non-A, non-B type. A single case of hepatitis A was seen. Hepatitis B and non-A, non-B affect equally young men and women (mean age, 29 and 28, respectively), and infection occurs, for both types of hepatitis, by the parenteral route. More than 90% of cases recovered completely. The search for markers of hepatitis B virus in subjects with chronic liver diseases has shown that the B virus plays an important role in these diseases in Morocco: 6.7% of controls, 38.5% of cirrhotics and 40.9% of patients with chronic hepatitis were carriers of HBsAg. The anti-hepatitis Bc antibody was present in 53.3% of the control population, in 86.5% of cirrhotics and 90.9% of active chronic hepatitis patients. Hepatocellular carcinoma is relatively rare in Morocco, representing 5.9% of hepatic tumours and accounting for one hospitalization out of 84. It occurs in older subjects (mean age, 58 years) and more often in men than in women (40:23). The presence of HBsAg was investigated in 46 patients and 379 controls: it was found in 17% of hepatocellular carcinoma patients and 4.7% of controls. Anti-HBc antibodies were present in 76.8% of patients and 53.3% of controls.
D000293:Adolescent; D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000209:etiology*; D005260:Female; D006506:Hepatitis A / Q000175:diagnosis; D006509:Hepatitis B / Q000175:diagnosis; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006512:Hepatitis B Core Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006526:Hepatitis C / Q000175:diagnosis; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009018:Morocco
D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens
Hépatites virales aigües et marqueurs du virus HB dans les maladies chroniques du foie et dans les cancers primitifs du foie.