[Changes in the state of the histamine--diamine oxidase and serotonin--monoamine oxidase systems and the activity of the sympatho-adrenal system following experimental occlusion of the aortic trifurcation in dogs].
Experiments on 12 dogs have shown that alterations in the intrasystemic parameters of histamine-diamine oxidase, serotonin-monoamine oxidase, adrenaline-noradrenaline and in the intersystemic patterns of adrenaline-histamine indicate the biological adaptation under conditions of embolism of aorta trifurcation induced by 3-hour occlusion. Alterations in the activity of the enzymes studied underlie the adaptational syndrome. During 6-hour occlusions the activity of monoamine oxidase was relatively decreased. Meanwhile the content of serotonin and noradrenaline remained at a high level. These amines might participate in the development of pronounced hypoxic impairments seen in the course of the observation period. It is recommended that adrenoblockers and inhibitors of synthesis of serotonin or serotonin-reactive structures may be used for correction of metabolic disorders.
D000208:Acute Disease; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood*; D000818:Animals; D001018:Aortic Diseases / Q000097:blood*; D004285:Dogs; D004837:Epinephrine / Q000097:blood; D005260:Female; D006632:Histamine / Q000097:blood*; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood*; D018377:Neurotransmitter Agents / Q000097:blood*; D009638:Norepinephrine / Q000097:blood; D012701:Serotonin / Q000097:blood; D014655:Vascular Resistance
D018377:Neurotransmitter Agents; D012701:Serotonin; D006632:Histamine; D006631:Amine Oxidase (Copper-Containing); D008995:Monoamine Oxidase; D009638:Norepinephrine; D004837:Epinephrine
Izmenenie sostoianii sistem gistamin--diaminoksidaza, serotonin--monoaminoksidaza i aktivnosti simpatiko-adrenalovoĭ sistemy pri éksperimental'noĭ okkliuzii trifurkatsii aorty u sobak.