The eye as a sanctuary in acute lymphoblastic leukaemia.
Leukaemic infiltration of the anterior chamber of the eye was the only sign of relapse in two children with acute lymphoblastic leukaemia who had been off treatment for two and four months. The malignant cells had probably been present in the eye since the onset of the disease.
D000867:Anterior Chamber / Q000473:pathology*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000517:prevention & control; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D007498:Iris / Q000473:pathology; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage
D000970:Antineoplastic Agents; D008727:Methotrexate