title: [Co-translation folding, compartmentalization and modification of proteins].
abstract: Transmembrane transport of polypeptide chains in the process of their synthesis on membrane-bound ribosomes and enzymic modification of the nascent polypeptides on membranes are reviewed. The possible role of ribosomes in protein folding and some other unsolved problems are discussed.
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism; D001692:Biological Transport; D010450:Endopeptidases / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism; D008565:Membrane Proteins; D008954:Models, Biological; D010452:Peptide Biosynthesis; D010455:Peptides / Q000235:genetics / Q000378:metabolism; D010458:Peptidyl Transferases / Q000378:metabolism; D014176:Protein Biosynthesis; D011487:Protein Conformation; D021382:Protein Sorting Signals; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D018160:Receptors, Cytoplasmic and Nuclear; D018000:Receptors, Peptide; D012697:Serine Endopeptidases
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins; D010455:Peptides; D021382:Protein Sorting Signals; D011506:Proteins; D011956:Receptors, Cell Surface; D018160:Receptors, Cytoplasmic and Nuclear; D018000:Receptors, Peptide; C036318:signal peptide receptor; D010458:Peptidyl Transferases; D010450:Endopeptidases; D012697:Serine Endopeptidases; C026515:type I signal peptidase
vernacular_title: Kotransliatsionnoe svorachivanie, kompartmentalizatsiia i modifikatsiia belka.