Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes.
The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D005796:Genes; D006023:Glycoproteins / Q000235:genetics*; D008957:Models, Genetic; D014158:Transcription, Genetic; D014346:Trypanosoma brucei brucei / Q000235:genetics*; D014643:Variant Surface Glycoproteins, Trypanosoma
D006023:Glycoproteins; D014643:Variant Surface Glycoproteins, Trypanosoma; D004262:DNA Restriction Enzymes