[Effect of psychotropic drugs on the pharmacokinetics of lithium].
It was established in mouse experiments that tofranyl and ftoracizin promote rapid attainment of the maximum level of Li+ in tissues (rather than in blood) after their combined administration with LiCl. Haloperidol and to a less measure triphthazin, aminazin and phenazepam provide for Li+ accumulation in some of the organs at a higher level attainable by administering lithium chloride alone.
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000494:pharmacology; D002746:Chlorpromazine / Q000494:pharmacology; D005260:Female; D006220:Haloperidol / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D008094:Lithium / Q000378:metabolism*; D008297:Male; D051379:Mice; D010640:Phenothiazines / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000494:pharmacology*; D014018:Tissue Distribution; D014268:Trifluoperazine / Q000494:pharmacology
D014151:Anti-Anxiety Agents; D000929:Antidepressive Agents, Tricyclic; D001570:Benzodiazepinones; D010640:Phenothiazines; D011619:Psychotropic Drugs; D001569:Benzodiazepines; D014268:Trifluoperazine; C001228:fluoracizine; C017928:phenazepam; D008094:Lithium; D006220:Haloperidol; D007099:Imipramine; D002746:Chlorpromazine
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