[Beta-endorphin in pituitary adenomas before surgery and in the postoperative period].
The content of beta-endorphin, ACTH, and cortisol was studied in 20 patients with hormonally-active, somatotropic hormone-secreting, prolactin-secreting, and hormonally inactive adenomas of the hypophysis before operation and in the early postoperative period. Before operation the basal level of hormones was within normal physiological fluctuations. In a favourable postoperative period the beta-endorphin level increased, while the ACTH content was low. In patients with an unfavourable postoperative period the content of beta-endorphin and ACTH was reduced as compared to the content before the operation. These data suggest that beta-endorphin plays an important role in the development of the organism's adaptation reactions to the surgical intervention.
D000236:Adenoma / Q000097:blood* / Q000601:surgery; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D004723:Endorphins / Q000097:blood*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000097:blood* / Q000601:surgery; D011184:Postoperative Period; D001615:beta-Endorphin
D004723:Endorphins; D001615:beta-Endorphin; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Beta-éndorfin pri adenomakh gipofiza do operatsii i v posleoperatsionnom periode.