title: Selectivity of alpha 1 and alpha 2 adrenergic agonists and antagonists.
abstract: The recent contributions in the selectivity of ligands acting at the adrenergic alpha-receptor toward pre- and post-synaptic receptors (i.e. alpha 1 and alpha 2-receptors) are reviewed. Furthermore, tissue differences and possible sub-classification of pre- and post-synaptic alpha-receptor types are discussed.
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D004220:Disulfides / Q000494:pharmacology; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D009928:Organ Specificity; D010643:Phenoxybenzamine / Q000494:pharmacology; D010883:Piperoxan / Q000494:pharmacology; D011073:Polyamines / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000145:classification; D015016:Yohimbine / Q000494:pharmacology
chemical_list: D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D004220:Disulfides; D007093:Imidazoles; D011073:Polyamines; D011942:Receptors, Adrenergic, alpha; D010643:Phenoxybenzamine; D015016:Yohimbine; D010883:Piperoxan