Gamma-glutamyltransferase in Morris hepatomas 5123D passaged in Buffalo and in F1 (Buffalo x Wistar) rats.
Comparative biochemical and immunological investigations were performed on purified gamma-glutamyltransferase from the Morris hepatoma 5123D and from the 5123D/AS variant passaged in F1 (Buffalo x Wistar) rats. The enzyme was also localized in hepatoma sections by immunofluorescent technique. The obtained results confirm the hypothesis that low gamma-glutamyltransferase activity in Morris hepatoma 5123D/AS is caused by the enzymatic protein defficiency and not by the inhibition of the enzyme.
D000818:Animals; D005455:Fluorescent Antibody Technique; D008114:Liver Neoplasms, Experimental / Q000201:enzymology*; D009368:Neoplasm Transplantation; D051381:Rats; D014184:Transplantation, Homologous; D005723:gamma-Glutamyltransferase / Q000032:analysis* / Q000276:immunology
D005723:gamma-Glutamyltransferase