Increased alveolar epithelial permeability in cigarette smokers.
Two indices of alveolar epithelial permeability were derived in man by a non-invasive method. The rate of transfer of 99mTc DTPA (diethylenetriamine penta-acetate) from the lung into the blood was measured and a significantly greater (P less than 0.001) transfer rate was found in symptomless cigarette smokers compared with non-smokers.
D000328:Adult; D000336:Aerosols; D001682:Biological Availability; D002199:Capillary Permeability; D006207:Half-Life; D006801:Humans; D007553:Isotope Labeling; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D004369:Pentetic Acid / Q000008:administration & dosage / Q000378:metabolism; D011650:Pulmonary Alveoli / Q000098:blood supply*; D012907:Smoking / Q000503:physiopathology*; D013667:Technetium
D000336:Aerosols; D013667:Technetium; D004369:Pentetic Acid