Gadolinium DTPA (an NMR proton imaging contrast agent): chemical structure, paramagnetic properties and pharmacokinetics.
The structure, chemical properties, metabolic pathway and NMR contrast efficacy of Gadolinium-DTPA are described. This reagent has great promise as a contrast agent in NMR proton imaging, and clinical trials have been initiated in England and Germany.
D000818:Animals; D003287:Contrast Media; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D004369:Pentetic Acid / Q000378:metabolism; D011817:Rabbits; D014018:Tissue Distribution
D003287:Contrast Media; D004369:Pentetic Acid