Autoradiographic demonstration of alpha 2 adrenoceptors in the bovine neurohypophysis.
Autoradiography of sections from neurohypophyses treated with tritiated clonidine has shown specific binding to alpha 2-adrenoceptor sites in the neurohypophysis but not in the intermediate lobe. Other studies have shown that alpha 2 agonists such as clonidine can cause a fall in circulating antidiuretic hormone; it is therefore possible to speculate that this action could be a direct one on the neurohypophysis since the appropriate binding sites have been shown to exist.
D000818:Animals; D001345:Autoradiography; D002417:Cattle; D003000:Clonidine; D009481:Neurophysins / Q000378:metabolism; D010904:Pituitary Gland, Posterior / Q000378:metabolism*; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism*
D009481:Neurophysins; D011942:Receptors, Adrenergic, alpha; D003000:Clonidine