title: [Configuration and properties of a binding site for thyroid hormones on a specific receptor].
abstract: An analysis has been carried out of data available in literature on structure-function relationships for thyroid hormones, namely thyroxine, triiodothyronine and their analogues. The configuration and dimensions of the hormone-binding site of the receptor in a hormone-receptor complex are described. The receptor is shown to have a strained conformation in the complex. The analysis is indicative of the existence of two types of hormone-receptor complexes, a particular type being determined by the dimensions of analogues.
mesh_terms: D001665:Binding Sites; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D011956:Receptors, Cell Surface / Q000378:metabolism*; D011988:Receptors, Thyroid Hormone; D013329:Structure-Activity Relationship; D013974:Thyroxine / Q000031:analogs & derivatives / Q000378:metabolism*; D014284:Triiodothyronine / Q000031:analogs & derivatives / Q000378:metabolism*
chemical_list: D011956:Receptors, Cell Surface; D011988:Receptors, Thyroid Hormone; D014284:Triiodothyronine; D013974:Thyroxine
vernacular_title: Konfiguratsiia i svoĭstva oblasti sviazyvaniia tireoidnykh gormonov na spetsificheskom retseptore.