[Effect of thyroxine on the activity of rat heart and liver mitochondrial cytochrome C-oxidase and Mg-activated ATP-ase].
Effect of thyroxine on the activity of mitochondrial enzymes was studied in rats with hypothyrosis caused by thyroidectomy as well as in the rats, protein biosynthesis in which was stimulated by partial hepatectomy and/or inhibited by actinomycin D administration. Tissue- and enzyme-specific action of the hormone was shown to depend on the nature of the enzyme and on the state of cell systems, synthesizing the enzyme. Thyroxine was shown to be an inductor of cytochrome c oxidase in liver and heart tissues and of MG2+-ATPase- in liver tissue.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase; D003609:Dactinomycin / Q000494:pharmacology; D003576:Electron Transport Complex IV / Q000378:metabolism*; D004790:Enzyme Induction; D006498:Hepatectomy; D007037:Hypothyroidism / Q000201:enzymology*; D008297:Male; D008929:Mitochondria, Heart / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology*; D051381:Rats; D013974:Thyroxine / Q000494:pharmacology*
D003609:Dactinomycin; D003576:Electron Transport Complex IV; D000251:Adenosine Triphosphatases; D017301:Ca(2+) Mg(2+)-ATPase; D013974:Thyroxine
Vliianie tiroksina na aktivnost' tsitokhrom C-oksidazy i Mg-aktiviruemoĭ ATF-azy mitokhondriĭ pecheni i serdtsa krys.