title: [Diagnosis and treatment of endogenous psychoses (author's transl)].
abstract: This article attempts to summarize our knowledge of the diagnosis and treatment of endogenous psychoses from the biological psychopharmacological aspect. Besides the results of pharmacological research which lead to the "amine hypothesis" of endogenous psychoses, results from psychoneuroendocrinology are referred to which show that a laboratory diagnosis of the endogenous depressions is not impossible in the long run. Schizophrenia research findings show that the disease picture of "schizophrenia" can be differentiated into at least two completely different disease entities. Finally the results of studies on the connection between the serum levels and clinical activity of antidepressives and the difficulties of method arising in the studies are reported.
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D011954:Receptors, Dopamine / Q000187:drug effects; D012306:Risk; D012559:Schizophrenia / Q000175:diagnosis
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D018377:Neurotransmitter Agents; D011954:Receptors, Dopamine
vernacular_title: Diagnose und Therapie endogener Psychosen. Biochemische und pharmakologische Aspekte.