title: Pulmonary and hepatic activities of membrane-bound enzymes in man and rat.
abstract: The lung of adult man contains several times more 5'-nucleotidase (EC 3.1.3.5), alkaline phosphatase (EC 3.1.3.1) and gamma-glutamyl-transpeptidase (EC 2.3.2.2) per gram than does that of the 12- to 16-week fetus. In rat lung, too, there is a drastic developmental rise in these activities. Opposite changes in two of the enzymes occur during hepatic differentiation: alkaline phosphatase decreases in the rat, and gamma-glutamyl-transpeptidase is ten times higher in the fetal than in the adult liver of both species.
mesh_terms: D015720:5'-Nucleotidase; D000375:Aging; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D005260:Female; D006801:Humans; D008099:Liver / Q000196:embryology / Q000201:enzymology*; D008168:Lung / Q000196:embryology / Q000201:enzymology*; D008297:Male; D009708:Nucleotidases / Q000378:metabolism*; D009928:Organ Specificity; D011247:Pregnancy; D051381:Rats; D013045:Species Specificity; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
chemical_list: D005723:gamma-Glutamyltransferase; D009708:Nucleotidases; D000469:Alkaline Phosphatase; D015720:5'-Nucleotidase