title: Guanylate cyclase activation of nitroprusside and nitrosoguanidine is related to formation of S-nitrosothiol intermediates.
mesh_terms: D000818:Animals; D003545:Cysteine / Q000031:analogs & derivatives / Q000494:pharmacology; D004229:Dithiothreitol / Q000031:analogs & derivatives / Q000494:pharmacology; D004789:Enzyme Activation; D005292:Ferricyanides / Q000494:pharmacology*; D005978:Glutathione / Q000031:analogs & derivatives / Q000494:pharmacology; D006162:Guanylate Cyclase / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008624:Mercaptoethylamines / Q000494:pharmacology; D009599:Nitroprusside / Q000494:pharmacology*; D009603:Nitroso Compounds / Q000494:pharmacology*; D009604:Nitrosoguanidines / Q000494:pharmacology*; D026422:S-Nitrosoglutathione; D026403:S-Nitrosothiols; D013329:Structure-Activity Relationship; D013863:Thioglucosides / Q000494:pharmacology; D014633:Valine / Q000031:analogs & derivatives / Q000494:pharmacology
chemical_list: D005292:Ferricyanides; D008624:Mercaptoethylamines; D009603:Nitroso Compounds; D009604:Nitrosoguanidines; D026403:S-Nitrosothiols; D013863:Thioglucosides; D009599:Nitroprusside; D026422:S-Nitrosoglutathione; C025443:S-nitroso-2-mercaptoethylamine; C024941:S-nitrosodithiothreitol; C024944:S-nitroso-beta-D-thioglucose; C024942:S-nitrosopenicillamine; C021315:S-nitrosocysteine; D006162:Guanylate Cyclase; D005978:Glutathione; D014633:Valine; D003545:Cysteine; D004229:Dithiothreitol