title: Pharmacology of ocular drugs. 1. Timolol maleate.
abstract: Timolol maleate is a new, potent ocular antihypertensive that has an effect additive with other antiglaucoma medications. It does not cause miosis and is relatively free of ocular complications, although a few have been documented. Timolol does exacerbate asthma and should not be used in patients with a history of this disease. It should be used with caution in cases of significant cardiovascular disease and may produce occasional psychic disturbances. In general, timolol is a potent, effective, and relatively safe drug with few ocular side effects but should be used with appropriate care.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D011412:Propanolamines / Q000494:pharmacology*; D013999:Timolol / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; D013999:Timolol