title: Recent biosynthetic studies on beta-lactam antibiotics.
abstract: Recent experimental observations on the cell-free formation of penicillins and cephalosporins in protoplast lysates from C. acremonium are described. Conversion of radiolabelled penicillin N into deacetoxycephalosporin C is described. A proposal is made about the general types of mechanism involved in these conversions.
mesh_terms: D000164:Acremonium / Q000378:metabolism; D002511:Cephalosporins / Q000096:biosynthesis*; D009154:Mutation; D010406:Penicillins / Q000096:biosynthesis*; D011523:Protoplasts / Q000378:metabolism
chemical_list: D002511:Cephalosporins; D010406:Penicillins