[Mathematical model of fluid transport in the convoluted portion of the proximal kidney tubules and surrounding capillaries].
Simulating transport of fluid and ions among proximal tubule, interstice and capillaries the mechanism of fluid transport in the kidney was studied. A mathematical model as a system of differential equations was processed with a numerical method by a digital computer. The results showed that 96% of fluid from the proximal convolution into interstice were reabsorbed because of the difference of osmotic pressures caused by HCO3-, ions and 4% -- at the expense of oncotic pressure gradient. Fluid transport from interstice into capillaries is realized by the higher oncotic pressure caused by proteins as a result of previous plasma filtration in the nephron glomerulus.
D001692:Biological Transport; D001826:Body Fluids / Q000378:metabolism*; D002196:Capillaries / Q000378:metabolism; D004058:Diffusion; D007473:Ion Channels / Q000378:metabolism; D007687:Kidney Tubules, Proximal / Q000098:blood supply / Q000378:metabolism*; D008433:Mathematics; D008954:Models, Biological; D009997:Osmotic Pressure
D007473:Ion Channels
Matematicheskaia model' transporta zhidkosti v izvitoĭ chasti proksimal'nogo kanal'tsa pochek i okruzhaiushchikh kapilliarakh.