title: Single anion channels of frog rod plasma membrane.
abstract: Anion channels have been found in the plasma membrane of the outer and inner segment of the isolated retinal rod by means of the patch voltage-clamp technique. The permeability of the channels for different anions follows a sequence: Cl- greater than F- greater than NO3- greater than propionate; the channel conductance in the fully open state is 200 +/- 30 pS measured in 108 mM NaCl. The non-linear character of the current-voltage relationship at membrane potentials from -40 to -20 mV suggests that these anion channels may be involved in receptor potential generation through an electrogenic mechanism.
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D002463:Cell Membrane Permeability; D002712:Chlorides / Q000502:physiology; D005459:Fluorides / Q000502:physiology; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials; D009566:Nitrates / Q000502:physiology; D010786:Photoreceptor Cells / Q000166:cytology / Q000502:physiology*; D011422:Propionates / Q000502:physiology; D011898:Ranidae
chemical_list: D002712:Chlorides; D007473:Ion Channels; D009566:Nitrates; D011422:Propionates; D005459:Fluorides