[Etiopathogenetic considerations on a case record of cirrhotic patients from western Sicily].
In 38.6% of 88 patients without anamnesis of alcoholism and/or chronic exposure to hepatotoxic drugs, selected among 120 cirrhotic subjects subsequently observed, the illness was HBV related. Markers indicating active viral replication (anti-HBc, HBsAg, HBeAg or anti-HBe) were detected in 48% of patients with active cirrhosis, and in 26% with inactive cirrhosis. It is suggested that high titers of CF antibodies anti-HSV and anti-CMV observed in several patients, indicate either reactivation of latent infections or over-infections. The absence of alcoholism and/or chronic exposure to hepatotoxic drugs, and the absence of viral markers, suggest in 61% of the 88 cirrhotic subjects either a nonA-nonB viruses etiology of the illness, or other etiological factors that escape available diagnostic and prophylactic procedures.
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D003587:Cytomegalovirus / Q000276:immunology; D005260:Female; D006509:Hepatitis B / Q000150:complications; D006511:Hepatitis B Antigens / Q000032:analysis; D006526:Hepatitis C / Q000150:complications; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D000914:Antibodies, Viral; D006511:Hepatitis B Antigens
Considerazioni etiopatogenetiche su una casistica di pazienti cirrotici della Sicilia occidentale.