[Leukotrienes].
The paper deals with the structure and nomenclature, distribution, metabolism and biological role of leukotrienes, a group of derivatives of eicosanic acids, in the human and animal organism. Leukotrienes can cause contraction of smooth muscles, stimulate the function of leukocytes, and affect the permeability of vessels and arterial pressure. The participation of these substances in the inflammatory processes and allergic reactions is discussed.
D000818:Animals; D001794:Blood Pressure; D000001:Calcimycin / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007975:Leukotriene B4 / Q000096:biosynthesis / Q000494:pharmacology / Q000502:physiology; D017999:Leukotriene E4; D008407:Mast Cells / Q000378:metabolism; D009119:Muscle Contraction; D009504:Neutrophils / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D013189:SRS-A / Q000031:analogs & derivatives* / Q000096:biosynthesis / Q000494:pharmacology / Q000502:physiology; D013329:Structure-Activity Relationship; D014590:Uterine Contraction
D005227:Fatty Acids; D013189:SRS-A; D007975:Leukotriene B4; D000001:Calcimycin; D017999:Leukotriene E4
Leĭkotrieny.