Primary rhabdomyosarcoma of the leptomeninx. Clinical, neuroradiological and pathological aspects.
Report of an eight-year-old boy presenting with untreatable focal epilepsy and slowly progressing hemiparesis combined with personality changes. Continuous diagnostic efforts eventually resulted in the diagnosis of a primary intracranial rhabdomyosarcoma several months later. The delay in making the correct diagnosis was due to the fact that the malignant process originated as a diffuse involvement of the leptomeninx, and only in later stages a tumor mass developed. Nosology and histogenesis of primary intracranial rhabdomyosarcomas are discussed.
D001099:Arachnoid / Q000473:pathology*; D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D010841:Pia Mater / Q000473:pathology*; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed