title: Intrauterine contraception with levonorgestrel: a comparative randomised clinical performance study.
abstract: Two levonorgestrel-releasing intrauterine devices (IUD) with different release rates of levonorgestrel and a 'Nova-T' copper-releasing device were compared in a randomised clinical performance study. 327 women had a levonorgestrel IUD and 156 women a nova-T device inserted postmenstrually. No statistically significant differences in the reasons for termination between the three devices were found in 12 months. The continuation rates for the two levonorgestrel IUDs were 84.1 and 81.4 and for the nova-T device 87.5. Duration of menstrual bleeding and spotting was highly significantly shorter with the levonorgestrel IUDs than with the nova-T device. There were no infections.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003271:Contraceptive Agents, Female / Q000592:standards*; D005260:Female; D006801:Humans; D007433:Intrauterine Device Expulsion; D007435:Intrauterine Devices, Copper / Q000592:standards*; D007436:Intrauterine Devices, Medicated / Q000592:standards*; D016912:Levonorgestrel; D009644:Norgestrel / Q000592:standards*; D010146:Pain / Q000517:prevention & control; D011897:Random Allocation
chemical_list: D003271:Contraceptive Agents, Female; D009644:Norgestrel; D016912:Levonorgestrel