title: Effects of alcohol and flunitrazepam on mood and performance in healthy young men.
abstract: Alcohol and flunitrazepam did not have any pharmacokinetic interactions when ingested 30 minutes apart at night. Flunitrazepam, 2.0 mg, but not 0.8 Gm/kg alcohol had a strong deleterious effect on performance shortly after ingestion. The combination of flunitrazepam and alcohol impaired tracking in a divided attention task the following morning.
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001944:Breath Tests; D002940:Circadian Rhythm; D004334:Drug Administration Schedule; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology*; D005445:Flunitrazepam / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007700:Kinetics; D008297:Male; D013647:Task Performance and Analysis
chemical_list: D014151:Anti-Anxiety Agents; D000431:Ethanol; D005445:Flunitrazepam