Receptor to effector coupling in the receptor-dependent adenylate cyclase system.
The mode of coupling between the components of hormone-regulated adenylate cyclases is discussed. In view of the structural knowledge and kinetic experiments, an attempt is made to analyze critically the current molecular models suggested for the mode of hormone stimulation and hormone inhibition of adenylate cyclase.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000378:metabolism; D006728:Hormones / Q000494:pharmacology*; D008954:Models, Biological; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000378:metabolism*
D006728:Hormones; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D006160:Guanosine Triphosphate; D000242:Cyclic AMP; D000262:Adenylyl Cyclases