[Value of cefotaxime in gram-negative bacterial meningitis. Apropos of 3 developmental forms in neonates and infants].
Three cases of meningitis with E. coli and H. influenzae are reported. They illustrate the recrudescence and relapse in bacterial meningitis. After the failure of initial antibiotic therapy, the treatment by Cefotaxime allowed a good outcome in all the cases. On account of the bacteriological, pharmacological and clinical data the authors advise using Cefotaxime in first purpose in meningitis with common gram negative bacilli.
D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy*; D002439:Cefotaxime / Q000134:cerebrospinal fluid / Q000627:therapeutic use*; D004927:Escherichia coli Infections / Q000188:drug therapy; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007700:Kinetics; D008297:Male; D008581:Meningitis / Q000150:complications / Q000188:drug therapy*; D008583:Meningitis, Haemophilus / Q000188:drug therapy; D012008:Recurrence
D002439:Cefotaxime
Intérêt du céfotaxime dans les méningites à bacille Gram négatif. A propos de 3 formes évolutives du nouveau-né et du nourrisson.