title: [Detection and follow-up of the high risk group for hepatocellular carcinoma].
abstract: To determine the high risk group for hepatocellular carcinoma (H.C.C.) 79 patients with diagnosed H.C.C. were studied retrospectively and compared with 15,948 healthy subjects regarding their prior history of liver disease, positivity of HBV related factors and s-GOT. A strong association of HBsAg and H.C.C. was demonstrated and the following factors were found in the high risk group: (1) prior history of liver disease, (2) positive HBsAg, (3) prior history of blood transfusion, and (4) males between 45 and 65 years. For follow-up of the high risk group for H.C.C., the use of a "liver-note book" for individuals in this group is proposed.
mesh_terms: D000328:Adult; D001219:Aspartate Aminotransferases / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000276:immunology; D005500:Follow-Up Studies; D006511:Hepatitis B Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008107:Liver Diseases / Q000276:immunology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012306:Risk
chemical_list: D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens; D001219:Aspartate Aminotransferases