title: [Hemorrhagic pulmonary edema and cardiac failure following isolated head injury. Treatment with dobutamine and nitroglycerin (author's transl)].
abstract: A 12 year boy with an isolated head injury and subdural hematoma developed neurogenic pulmonary edema and intraoperatively a low cardiac output syndrome. The postoperatively depressed cardiac function and hemorrhagic pulmonary edema were treated with Dobutamine and Nitroglycerin given intravenously. The beta-1-stimulating catecholamine was used because of its positive inotropic effect, to reduce pulmonary capillary pressure and to improve the afterload. Nitroglycerin applied in a low dosage with exclusive venodilator effect was added for treatment of pulmonary edema and left ventricular failure. About 2 1/2 h after the start of the treatment pulmonary edema had subsided and circulation was stabilized.
mesh_terms: D001930:Brain Injuries / Q000150:complications*; D002303:Cardiac Output, Low / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D004280:Dobutamine / Q000627:therapeutic use; D006408:Hematoma, Subdural / Q000150:complications / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D005996:Nitroglycerin / Q000627:therapeutic use; D011654:Pulmonary Edema / Q000188:drug therapy / Q000209:etiology*
chemical_list: D004280:Dobutamine; D005996:Nitroglycerin
vernacular_title: Hämorrhagisches Lungenäodem und Herzkreislaufinsuffizienz nach isoliertem Schädelhirntrauma. Kombinierte Behandlung mit Dobutamin und Nitroglycerin.