title: [Nausea and vomiting during chemotherapy of malignant tumors].
abstract: Nausea and vomiting are frequent and unpleasant side effects of cancer chemotherapy. Current concepts of pathophysiology and clinical aspects of nausea and vomiting are reviewed. Individual and therapeutic factors are discussed which greatly modify the degree of vomiting. The commercially available antiemetics are tabulated and the individual classes of antiemetics are described. Finally, consideration is given to new approaches to the treatment of nausea and vomiting, including the search for new compounds and better use of currently available agents.
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D064420:Drug-Related Side Effects and Adverse Reactions; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D014839:Vomiting / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology
chemical_list: D000932:Antiemetics; D014150:Antipsychotic Agents; D006634:Histamine H1 Antagonists; D003975:Diazepam
vernacular_title: Nausea and Erbrechen bei der Chemotherapie maligner Tumoren.