Sympathoadrenomedullary hyperactivity in the neuroleptic malignant syndrome: a case report.
The authors describe a patient with the neuroleptic malignant syndrome whose excessive catecholamine excretion indicates hyperactivity of the sympathoadrenomedullary component of the autonomic nervous system. Their finding provides a physiological basis for using catecholamine blocking agents to treat some patients with this syndrome.
D000313:Adrenal Medulla / Q000187:drug effects*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001833:Body Temperature Regulation / Q000187:drug effects; D004837:Epinephrine / Q000652:urine; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009127:Muscle Rigidity / Q000139:chemically induced; D009638:Norepinephrine / Q000652:urine; D012563:Schizophrenia, Paranoid / Q000188:drug therapy; D013564:Sympathetic Nervous System / Q000187:drug effects*; D014202:Tremor / Q000139:chemically induced
D014150:Antipsychotic Agents; D009638:Norepinephrine; D004837:Epinephrine