[Sulfasalazine enema in acute left-sided ulcerative colitis (author's transl)].
In a double-blind study comprising 33 patients (24 males and 9 females) the effects of sulfasalazine enema (3%) in acute left-sided ulcerative colitis was tested. The success rate of 73.6% is comparable with the results achieved with the oral treatment. The rate of side effects however was markedly reduced (no side effects occurred in our patients). Compared to the SASP-therapy with suppositories, the enema had the advantage of being applicable to more proximal parts of the colon.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004311:Double-Blind Method; D004733:Enema; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012460:Sulfasalazine / Q000008:administration & dosage* / Q000627:therapeutic use
D012460:Sulfasalazine
Salizylazosulfapyridin-Klysmen bei akuter linksseitiger Colitis ulcerosa. Ergebnisse einer Doppelblindstudie.