Descriptive studies of H-reflex recovery curves in psychiatric patients.
The rate of recovery of the H-reflex, an electrical evoked monosynaptic spinal cord reflex, was abnormally high (fast) in over 20% of unmedicated psychotic patients of all major diagnostic classes. A few patients had significantly lower H-reflex recovery curves. Chronic neuroleptic treatment produced relatively lower recovery curves, whereas fluoxetine, a specific serotonin uptake blocker, produced relatively higher curves.
D000293:Adolescent; D000328:Adult; D000341:Affective Disorders, Psychotic / Q000503:physiopathology*; D000928:Antidepressive Agents / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000494:pharmacology; D005260:Female; D006181:H-Reflex / Q000187:drug effects; D006801:Humans; D008094:Lithium / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D012023:Reflex, Monosynaptic / Q000187:drug effects; D012559:Schizophrenia / Q000503:physiopathology*
D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D008094:Lithium