title: Serotonin selectively inhibits growth cone motility and synaptogenesis of specific identified neurons.
abstract: The motile activity of growth cones of specific identified neurons is inhibited by the neurotransmitter serotonin, although other identified neurons are unaffected. As a consequence, affected neurons are unable to form electrical synapses, whereas other neurons whose growth is unaffected can still interconnect. This result demonstrates that neurotransmitters can play a prominent role in regulating neuronal architecture and connectivity in addition to their classical role in neurotransmission.
mesh_terms: D000828:Animal Population Groups; D000818:Animals; D002478:Cells, Cultured; D009474:Neurons / Q000187:drug effects* / Q000254:growth & development; D012701:Serotonin / Q000494:pharmacology*; D012908:Snails; D013569:Synapses / Q000187:drug effects*; D009435:Synaptic Transmission
chemical_list: D012701:Serotonin