Cyclic GMP releases calcium from leaky rod outer segments.
We show that cyclic GMP promotes the release of calcium from disks in whole rod outer segments by two different techniques. Most likely cyclic GMP causes a change in the permeability of the disk membrane.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002417:Cattle; D002463:Cell Membrane Permeability; D006152:Cyclic GMP / Q000494:pharmacology*; D010786:Photoreceptor Cells / Q000187:drug effects*; D012374:Rod Cell Outer Segment / Q000187:drug effects* / Q000378:metabolism
D006152:Cyclic GMP; D002118:Calcium