title: Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.
mesh_terms: D015660:7-Alkoxycoumarin O-Dealkylase; D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000378:metabolism* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004285:Dogs / Q000378:metabolism*; D004851:Epoxide Hydrolases / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D009154:Mutation; D010105:Oxygenases / Q000037:antagonists & inhibitors / Q000378:metabolism; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D013045:Species Specificity
chemical_list: D001580:Benzopyrenes; D001564:Benzo(a)pyrene; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; D015660:7-Alkoxycoumarin O-Dealkylase; D005982:Glutathione Transferase; D004851:Epoxide Hydrolases