Analysis of the major metabolite of delta 9-tetrahydrocannabinol in urine. V. Cross-reactivity of selected compounds in a radioimmunoassay.
The potential for cross-reactivity of an antiserum used to detect 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in a urine sample by a radioimmunoassay procedure has been examined. The degrees of cross-reactivity of 41 cannabinoids and non-cannabinoid phenolic constituents of Cannabis have been determined. In general, only (delta 8- or delta 9-THC type) cannabinoids of the dibenzopyran type structure were found to appreciably cross-react with the antiserum. Cross-reactivity was not observed with any non-cannabinoid constituent.
D002186:Cannabinoids / Q000276:immunology; D003429:Cross Reactions; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000276:immunology / Q000652:urine; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D011863:Radioimmunoassay
D002186:Cannabinoids; D007106:Immune Sera; C016780:11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; D013759:Dronabinol