Cytopathic and pathogenic properties of dengue type 2 virus reproduced in quail embryo fibroblast cultures.
Quail embryho fibroblast cultures are able to reproduce dengue type 2 virus up to high titres measured by TCID50 values. The reproduced virus at low passage levels was antigenically closely related to the original virus reproduced in newborn mouse brains in vivo, but was loosing its virulence for these animals.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D003716:Dengue Virus / Q000254:growth & development* / Q000276:immunology / Q000472:pathogenicity; D005347:Fibroblasts; D051379:Mice; D011784:Quail; D014776:Virus Cultivation
D000956:Antigens, Viral