[Immunohistochemical evidence of some peptidohormones in the central nervous system of normoglycemic and hyperglycemic rodents (author's transl)].
The content and the distribution of insulin, glucagon and somatostatin were studied in normoglycemic and hyperglycemic rodents by immunohistochemical techniques. A manifest Diabetes mellitus caused a striking decrease in somatostatin immunofluorescence. The insulin content suffered in a less pronounced manner. Data obtained with glucagon did not permit to draw unequivocal conclusions. In general, our findings speak about certain regulatory influence of the brain on glucose homeostasis.
D000818:Animals; D003411:Arvicolinae; D001921:Brain / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000378:metabolism / Q000662:veterinary; D005934:Glucagon / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism*; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats; D012376:Rodent Diseases / Q000378:metabolism; D012377:Rodentia / Q000378:metabolism*; D013004:Somatostatin / Q000378:metabolism*; D013045:Species Specificity
D007328:Insulin; D013004:Somatostatin; D005934:Glucagon
Zum immunhistochemischen Nachweis einiger Peptid-hormone im Zentralnervensystem von normo- und hyperglykämischen Nagern.