Inactivation of rhinovirus on human fingers by virucidal activity of glutaric acid.
Hand lotion containing 2% glutaric acid was significantly more effective than placebo in inactivating rhinovirus serotype 2 on the fingers of human volunteers. It may be possible to develop safe, cosmetically acceptable hand lotions which have durable virucidal activity and can interrupt the hand-to-hand transmission of rhinovirus colds.
D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000494:pharmacology*; D005385:Fingers; D005977:Glutarates / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans; D007509:Irritants; D008297:Male; D012229:Rhinovirus / Q000187:drug effects*; D012867:Skin / Q000382:microbiology*; D013997:Time Factors
D000998:Antiviral Agents; D005977:Glutarates; D007509:Irritants; C035736:glutaric acid