title: Reduced number of erythrocyte sodium pump units in essential hypertension.
abstract: The number of sodium pump units of erythrocytes measured with ouabain binding assay was significantly lower in 17 patients with essential hypertension (0.538 +/- 0.020 pmol/10(9) cells) than in 13 normotensive controls (0.673 +/- 0.031 pmol/10(9) cells) (p less than 0.01) and it was inversely correlated with erythrocyte sodium concentration (r = -0.86, p less than 0.01).
mesh_terms: D000328:Adult; D001665:Binding Sites; D004912:Erythrocytes / Q000201:enzymology* / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D010042:Ouabain / Q000378:metabolism; D012964:Sodium / Q000097:blood; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
chemical_list: D010042:Ouabain; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase