Effect of thymosin on T-lymphocyte rosette formation in Nigerian patients with different types of cancer.
Effects of thymosin fraction 5 on T-lymphocyte rosette formation in vitro were assessed in fourteen patients with hepatocellular carcinoma, twenty-one with Burkitt's lymphoma, thirteen with Hodgkin's disease and fifteen with breast cancer. Thymosin was found to cause a significant increase in T-lymphocyte rosette formation in patients with Burkitt's lymphoma and Hodgkin's disease but not in those with hepatocellular carcinoma and cancer of the breast. The significance of these results is discussed.
D000328:Adult; D001943:Breast Neoplasms / Q000276:immunology; D002051:Burkitt Lymphoma / Q000276:immunology; D006528:Carcinoma, Hepatocellular / Q000276:immunology; D005260:Female; D006689:Hodgkin Disease / Q000276:immunology; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology*; D009549:Nigeria; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D013947:Thymosin / Q000031:analogs & derivatives* / Q000494:pharmacology
C033782:thymosin fraction 5; D013947:Thymosin