Phenothiazines inhibit prolactin secretion in vitro. A possible role for calmodulin in stimulus--secretion coupling in the pituitary.
D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D002135:Calcium-Binding Proteins / Q000502:physiology*; D002147:Calmodulin / Q000502:physiology*; D007700:Kinetics; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D011188:Potassium / Q000494:pharmacology; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014268:Trifluoperazine / Q000494:pharmacology
D014150:Antipsychotic Agents; D002135:Calcium-Binding Proteins; D002147:Calmodulin; D014268:Trifluoperazine; D011388:Prolactin; D011188:Potassium