Lithium transport across squid axon membrane.
This paper describes the pathways for lithium transport across the axonal membrane of squid. We were able to show that the membrane of this classical neuronal preparation possesses the lithium transport mechanisms previously identified in red blood cells. It is now possible to predict that the lithium treatment-induced changes in choline and lithium transport that have been observed in red blood cells of manic depressive patients also occur in nerve membrane.
D000818:Animals; D001369:Axons / Q000187:drug effects / Q000378:metabolism*; D001693:Biological Transport, Active / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism; D002794:Choline / Q000494:pharmacology; D049832:Decapodiformes; D007700:Kinetics; D008094:Lithium / Q000378:metabolism*; D012964:Sodium / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D008094:Lithium; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D002794:Choline