title: [Biochemical aspects of enkephalin participation in the regulation of adrenergic effects on myocardium].
abstract: Stable derivative of Leu enkephalin, intravenously administered into rabbits and rats, decreased the rate of activation of creatine phosphokinase, aspartate- and alanine transaminases as well as corrected hypomagnesemia and the deteriorations in blood plasma osmolarity caused by novodrin necrosis of myocardium. The data obtained suggest that enkephalins appear to influence the system of cyclic nucleotides in myocardium.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D006321:Heart / Q000187:drug effects*; D007527:Isoenzymes; D007545:Isoproterenol / Q000633:toxicity*; D008274:Magnesium / Q000097:blood; D008297:Male; D009206:Myocardium / Q000201:enzymology / Q000378:metabolism*; D011817:Rabbits; D051381:Rats
chemical_list: D007527:Isoenzymes; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D000242:Cyclic AMP; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase; D006152:Cyclic GMP; D008274:Magnesium; D007545:Isoproterenol; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
vernacular_title: Biokhimicheskie aspekty uchastiia énkefalinov v reguliatsii adrenergicheskikh vliianiĭ na miokard.