title: Unusual electron microscopy findings in liver biopsies from patients with viral hepatitis B.
abstract: Electron microscopy of 57 needle biopsies from livers of 55 patients with chronic hepatitis, mostly of type B, revealed, in addition to typical hepatitis B virus nucleocapsids in 34 cases, also atypical intranuclear inclusions in 9 biopsies. These inclusions consisted of electron-dense particles similar in size to hepatitis B virus nucleocapsids. The possibility of an involvement of a hepatitis non-A non-B virus is discussed.
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002213:Capsid / Q000648:ultrastructure; D002467:Cell Nucleus / Q000382:microbiology; D002908:Chronic Disease; D006509:Hepatitis B / Q000382:microbiology*; D006515:Hepatitis B virus / Q000648:ultrastructure*; D006526:Hepatitis C / Q000382:microbiology; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008099:Liver / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged