title: Evaluation of a new antihypertensive agent. Minoxidil.
abstract: Minoxidil is a potent, long-acting, orally effective vasodilator that recently became available for general use in the United States. It is given with a diuretic and a beta-blocking drug to treat severe hypertension that cannot be controlled by conventional therapy. Fluid retention and hypertrichosis are the most common adverse reactions.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D001794:Blood Pressure / Q000187:drug effects; D001826:Body Fluids / Q000187:drug effects; D004232:Diuretics / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004487:Edema / Q000139:chemically induced; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008914:Minoxidil / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D011743:Pyrimidines / Q000008:administration & dosage*; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D000319:Adrenergic beta-Antagonists; D004232:Diuretics; D011743:Pyrimidines; D014665:Vasodilator Agents; D008914:Minoxidil