The effect of erythrosin B on infective larvae of bovine gastrointestinal nematodes.
The effect of erythrosin B and visible light on 3rd stage larvae of gastrointestinal nematodes of naturally-infected cattle was studied. Cattle were treated orally with erythrosin B at dosages of 30 and 40 mg kg-1 day-1 for as many as 17 days. Feces from treated and untreated animals were collected and prepared for culture. Third stage larvae were then collected by Baermannization and exposed to light. Both sunlight and artificial fluorescent light were shown to be toxic to 3rd-stage-larvae after treatment with erythrosin B. This toxic reaction was significant after only 2 consecutive daily treatments.
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology* / Q000517:prevention & control; D004923:Erythrosine / Q000494:pharmacology* / Q000627:therapeutic use; D005243:Feces / Q000469:parasitology; D005452:Fluoresceins / Q000494:pharmacology*; D007411:Intestinal Diseases, Parasitic / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D007814:Larva / Q000187:drug effects; D008027:Light; D008297:Male; D009068:Movement; D009348:Nematoda / Q000187:drug effects* / Q000502:physiology; D009349:Nematode Infections / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*
D005452:Fluoresceins; D004923:Erythrosine