[Treatment of hypotensive circulatory dysregulation with a combination of dihydroergotamine and etilefrine (author's transl)].
In 40 hypotensive patients with sympathicotonic orthostatic dysregulation and presenting the relevant subjective symptoms, a dosage of 3 times daily 2 mg dihydroergotamine or 20 mg etilefrine or the fixed combination of both drugs--Dihydergot plus--was compared inter-individually and by the double blind method. Under Dihydergot plus the strongest increase in resting blood pressure was achieved from 103/60 to 124/75 mm Hg. This drug also proved most effective in terms of the orthostatic test parameters, i.e. blood pressure, pulse pressure and heart rate. In the same manner the subjective symptoms were most favorably controlled by the combination product The relevant complaints expressed decreased from 50 to 9.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004087:Dihydroergotamine / Q000627:therapeutic use*; D004338:Drug Combinations; D005039:Etilefrine / Q000627:therapeutic use*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy*; D008875:Middle Aged; D010656:Phenylephrine / Q000031:analogs & derivatives*; D011187:Posture
D004338:Drug Combinations; D010656:Phenylephrine; D004087:Dihydroergotamine; D005039:Etilefrine
Therapie hypotoner Kreislaufregulationsstörungen mit einer Kombination aus Dihydroergotami plus Etilefrin.