The loss of paraben preservatives during freeze drying.
D002626:Chemistry, Pharmaceutical; D005612:Freeze Drying; D002955:Leucovorin; D008353:Mannitol; D010226:Parabens; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D013696:Temperature; D014835:Volatilization
D010226:Parabens; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D008353:Mannitol; D002955:Leucovorin