Inhibitors of IMP dehydrogenase prevent sindbis virus replication and reduce GTP levels in Aedes albopictus cells.
D000330:Aedes / Q000378:metabolism*; D000546:Amanitins / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D003609:Dactinomycin / Q000494:pharmacology; D006160:Guanosine Triphosphate / Q000378:metabolism*; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors*; D007658:Ketone Oxidoreductases / Q000037:antagonists & inhibitors*; D009173:Mycophenolic Acid / Q000494:pharmacology*; D009536:Niacinamide / Q000494:pharmacology; D010766:Phosphorylation; D012254:Ribavirin / Q000494:pharmacology*; D012263:Ribonucleosides / Q000494:pharmacology*; D012845:Sindbis Virus / Q000254:growth & development; D013830:Thiadiazoles / Q000494:pharmacology*; D014721:Vesicular stomatitis Indiana virus / Q000254:growth & development; D014779:Virus Replication / Q000187:drug effects*
D000546:Amanitins; D012263:Ribonucleosides; D013830:Thiadiazoles; D003609:Dactinomycin; D009536:Niacinamide; D012254:Ribavirin; C010852:2-amino-1,3,4-thiadiazole; D006160:Guanosine Triphosphate; D007168:IMP Dehydrogenase; D007658:Ketone Oxidoreductases; D009173:Mycophenolic Acid