Serum-mediated inhibition of lymphocyte Fc gamma receptors in glomerulonephritis.
Non-complement-fixing immune complexes were detected by EA rosette inhibition in the sera of 47% of patients with primary glomerulonephritis (GN) and 60% with GN associated with systemic disease. Fifteen patients with minimal-change nephrotic syndrome (MCNS) in relapse produced significantly greater inhibition than the sera from 11 who were in remission.
D000936:Antigen-Antibody Complex / Q000032:analysis*; D002478:Cells, Cultured; D005921:Glomerulonephritis / Q000276:immunology*; D006801:Humans; D011695:IgA Vasculitis / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D009404:Nephrotic Syndrome / Q000276:immunology; D010488:Polyarteritis Nodosa / Q000276:immunology; D011961:Receptors, Fc / Q000276:immunology*; D012397:Rosette Formation
D000936:Antigen-Antibody Complex; D011961:Receptors, Fc