title: [Kinin system components and blood serum proteinase inhibitors in hemorrhagic fever with renal syndrome].
abstract: In polyuric period of hemorrhagic fever with renal syndrome a distinct activation of the kinin system was observed in blood serum of patients; it was manifested as an increase in spontaneous BAEE-esterase and kallikreine activities as well as a decrease in kininogen content. Content of inhibitors of proteinases (alpha 1-antitrypsin) was increased within all the periods of hemorrhagic fever with renal syndrome, beginning from the I preoligouric period. The data obtained suggest that kinins are involved in pathogenesis and clinical manifestations of hemorrhagic fever with the renal syndrome.
mesh_terms: D000328:Adult; D003289:Convalescence; D006480:Hemorrhagic Fever with Renal Syndrome / Q000097:blood* / Q000209:etiology; D006801:Humans; D007705:Kinins / Q000097:blood*; D008875:Middle Aged; D011480:Protease Inhibitors / Q000097:blood*; D013997:Time Factors
chemical_list: D007705:Kinins; D011480:Protease Inhibitors
vernacular_title: Komponenty kininovoĭ sistemy i ingibitory proteinaz syvorotki krovi pri gemorragicheskoĭ likhoradke s pochechnym sindromom.