Detection of antibodies of the IgG and IgM classes to herpes simplex virus type 1 in cerebrospinal fluid and serum from four patients with herpes encephalitis.
Antibodies of IgG and IgM classes to Herpes simplex virus type 1 were detected, using the ELISA technique, in the cerebro-spinal fluid (CSF) and in the serum of four patients with encephalitis. All CSF and sera were positive for IgG antibodies; two CSF samples, which were collected quite early, were also positive for antibodies of IgM classes.
D000914:Antibodies, Viral / Q000032:analysis* / Q000134:cerebrospinal fluid; D004660:Encephalitis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006561:Herpes Simplex / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D018139:Simplexvirus / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M