Independence of circulating insulin levels of the increased glucose turnover in shivering dogs.
In dogs, selective insulin deficiency induced by simultaneous somatostatin and glucagon infusion does not alter the high rate of glucose utilization provoked by acute cold exposure. However, both in resting and in shivering dogs, lowering of plasma insulin decreases plasma glucose metabolic clearance significantly.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003080:Cold Temperature; D004285:Dogs; D005260:Female; D005934:Glucagon / Q000494:pharmacology; D007328:Insulin / Q000097:blood*; D008657:Metabolic Clearance Rate; D012768:Shivering; D013004:Somatostatin / Q000494:pharmacology
D001786:Blood Glucose; D007328:Insulin; D013004:Somatostatin; D005934:Glucagon