title: [Persistent generalized lymphadenopathy: pre-AIDS. First description of a case observed in Italy].
abstract: Persistent Generalized Lymphadenopathy (PGL) is considered a possible early stage of AIDS (pre-AIDS), caused by the same virus and characterized by the same immunologic abnormalities. So far, no case of PGL has been reported in Italy: therefore we describe a typical clinical history, immunologic studies and lymph-node histology of a young italian patient affected by PGL. We treated him with thymocyte protein extract (TP-1). We think PGL is not rare in Italy and probably a percentage of cases, especially in heroin addicts and homosexual males, is not recognized.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D000328:Adult; D006556:Heroin Dependence; D006716:Homosexuality; D006801:Humans; D007558:Italy; D008198:Lymph Nodes / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D008206:Lymphatic Diseases / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D008297:Male; D012192:Retroviridae Infections / Q000276:immunology* / Q000473:pathology; D013949:Thymus Extracts / Q000627:therapeutic use
chemical_list: D013949:Thymus Extracts; C031407:thymostimulin
vernacular_title: Linfadenopatia persistente generalizzata: pre-AIDS. Prima descrizione di un caso osservato in Italia.