[Sarcoidosis in a child disclosed by blindness with major hypercalcemia].
We report here a case of sarcoidosis, observed in a 12 year-old algerian girl. When the child was examined, at an advanced stage of the disease, her clinical condition was very critical, associating blindness, cachexia, hepatic and splenic enlargement, and major hypercalcaemia. Though chest roentgenograms were normal, the results of both functional pulmonary tests and broncho-alveolar lavage were pathologic. The diagnosis of sarcoidosis was confirmed by the finding of an elevated level of Angiotensin-converting enzyme, and by histologic lesions observed in liver, kidney and conjunctiva biopsies. The corticosteroid treatment improved the general condition, but it failed to better the visual state.
D001766:Blindness / Q000209:etiology*; D001980:Bronchi / Q000473:pathology; D002100:Cachexia / Q000209:etiology; D002648:Child; D003228:Conjunctiva / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis; D005260:Female; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D007703:Peptidyl-Dipeptidase A / Q000097:blood; D012507:Sarcoidosis / Q000175:diagnosis* / Q000628:therapy; D014605:Uveitis / Q000209:etiology; D014606:Uveitis, Anterior / Q000209:etiology
D007703:Peptidyl-Dipeptidase A
Sarcoïdose de l'enfant révélée par une cécité avec hypercalcémie majeure.