Thiopentone and fazadinium crash induction. A comparison with thiopentone and pancuronium.
A method of crash induction using fazadinium and thiopentone was studied in 100 patients not genuinely at risk from regurgitation. Speed and ease of intubation compared well with a previous study using pancuronium. Cardiovascular stability was not as good as with pancuronium and tachycardia was the major concern. Fourteen patients were assessed as 'difficult' to reverse and three recurarised.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000379:methods*; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D009469:Neuromuscular Junction / Q000187:drug effects; D010197:Pancuronium / Q000494:pharmacology; D011674:Pulse / Q000187:drug effects; D011726:Pyridinium Compounds / Q000494:pharmacology; D013874:Thiopental
D011726:Pyridinium Compounds; D010197:Pancuronium; D013874:Thiopental