title: [Treatment of therapeutically resistant paranoid schizophrenic patients with Moditen-depot combined with other psychotropic drugs and Leponex].
abstract: The results of treating 251 therapeutically resistant patients with paranoid schizophrenia by moditen-depo, its combination with other psychotic drugs or leponex was compared. The results obtained indicate that a comprehensive treatment (moditen-depo with other psychotropic drugs) and by leponex may be successfully applied to some of the paranoid schizophrenics resistant to moditen-depo and other neuroleptic drugs or their combinations. Comprehensive treatment appeared to be more effective in systematized delusions, the syndrome of psychic automatisms and in a crude emotional-volitional defect. Treatment by leponex was more efficacious in emotionally saturated nonsystematized delusions, pronounced disordered behaviour and mild manifestation of deterioration.
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000008:administration & dosage; D014150:Antipsychotic Agents / Q000008:administration & dosage; D003024:Clozapine / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D003863:Depression / Q000150:complications / Q000188:drug therapy; D003984:Dibenzazepines / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D005476:Fluphenazine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000008:administration & dosage*; D012075:Remission, Spontaneous; D012563:Schizophrenia, Paranoid / Q000150:complications / Q000188:drug therapy*
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations; D003984:Dibenzazepines; D011619:Psychotropic Drugs; C011825:fluphenazine depot; D003024:Clozapine; D005476:Fluphenazine
vernacular_title: Lechenie moditenom-depo s drugimi psikhotropnymi sredstvami i leponeksom terapevticheski rezistentnykh bol' nykh paranoidnoĭ shizofrenieĭ.