Differential equation model to study dynamic behaviour of globular proteins.
By regarding the globular proteins as spheroidal shaped bodies of uniform density, a differential equation model to study their low amplitude fluctuations was developed. It was then applied to the crystal structures of pancreatic trypsin inhibitor and ferrocytochrome c. The results were tested by comparing them with those of the dynamic simulation and temperature factor studies on the same proteins.
D000818:Animals; D002417:Cattle; D003574:Cytochrome c Group; D008433:Mathematics; D008961:Models, Structural; D011487:Protein Conformation; D011506:Proteins; D014359:Trypsin Inhibitor, Kazal Pancreatic
D003574:Cytochrome c Group; D011506:Proteins; D014359:Trypsin Inhibitor, Kazal Pancreatic