Synergistic effect of alpha chlorohydrin on the influence of copper ions on human spermatozoa.
Alpha chlorohydrin and copper ions at a very low concentration inhibit human spermatozoa motility in vitro due to alkylation of cysteine by alpha chlorohydrin. Alpha chlorohydrin has been reported to protect sperm motility and glycolysis from the inhibitory effect of copper ions.
D002728:Chlorohydrins / Q000494:pharmacology*; D003300:Copper / Q000494:pharmacology*; D004357:Drug Synergism; D006801:Humans; D007700:Kinetics; D008297:Male; D013081:Sperm Motility / Q000187:drug effects*; D000517:alpha-Chlorohydrin / Q000494:pharmacology*
D002728:Chlorohydrins; D003300:Copper; D000517:alpha-Chlorohydrin