Effect of lysine on survival of AKR leukemic mice.
The effect of lysine/arginine antagonism on the survival of mice with virally - produced leukemia was investigated by feeding AKR mice diets low in arginine with varying amounts of lysine. Over a period of one year, a diet containing 5.6% lysine and no arginine resulted in a significantly lower mortality than one with lower levels of lysine, plus arginine.
D000406:AKR murine leukemia virus; D000818:Animals; D001120:Arginine / Q000008:administration & dosage*; D005260:Female; D007942:Leukemia, Experimental / Q000151:congenital / Q000178:diet therapy*; D008239:Lysine / Q000008:administration & dosage*; D051379:Mice; D008806:Mice, Inbred AKR; D011897:Random Allocation; D018139:Simplexvirus / Q000187:drug effects
D001120:Arginine; D008239:Lysine