title: Processing of complex heteroduplexes in Escherichia coli and Cos-1 monkey cells.
abstract: Upon transformation into Escherichia coli or Cos-1 monkey cells, heteroduplex DNA made of two sequences containing many nucleotide mismatches yields a wide array of different molecules, some with a patchwork structure. Thus, complex heteroduplexes can be processed to generate many genetic variants.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002522:Chlorocebus aethiops; D004247:DNA / Q000032:analysis / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D009692:Nucleic Acid Heteroduplexes; D009693:Nucleic Acid Hybridization; D010957:Plasmids
chemical_list: D004269:DNA, Bacterial; D009692:Nucleic Acid Heteroduplexes; D004247:DNA; D004262:DNA Restriction Enzymes