[beta-Cell residual function in juvenile diabetes mellitus (author's transl)].
Estimation of C-peptide (IRCP) can be used to measure the residual beta-cell function in insulin treated diabetics. IRCP was estimated in 46 juvenile diabetics. A significant correlation between basal IRCP-levels and duration of diabetes as well as daily insulin requirement could be shown. There was no linear correlation between glucosuria and IRCP. However, patients with IRCP > 1,0 ng/ml had significantly lower glucosuria ( p < 0,005). Endogenous residual function of the beta-cells seems to be of importance for metabolic control in diabetic children.
D000293:Adolescent; D002096:C-Peptide / Q000097:blood; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006029:Glycosuria / Q000175:diagnosis; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D007515:Islets of Langerhans; D008297:Male; D008433:Mathematics; D013997:Time Factors
D002096:C-Peptide; D007328:Insulin
beta-Zell-Residualfunktion bei kindlichen Diabetikern.