title: Intraamniotic injection of methylene blue leading to methemoglobinemia in one of twins.
abstract: The practice of injecting pregnant women with methylene blue to detect membrane rupture and differentiate twin sacs is discussed. The authors recommend caution in the use of substances with potential adverse fetal effects.
mesh_terms: D000328:Adult; D000650:Amnion; D000743:Anemia, Hemolytic / Q000139:chemically induced; D004200:Diseases in Twins; D005321:Extraembryonic Membranes / Q000502:physiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000139:chemically induced*; D007267:Injections; D007743:Labor, Obstetric; D008708:Methemoglobinemia / Q000139:chemically induced*; D008751:Methylene Blue / Q000009:adverse effects*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D014427:Twins
chemical_list: D008751:Methylene Blue