The effect of somatostatin on blood flow through coronary bypass grafts in anesthetized man.
The effect of intravenous somatostatin on blood flow through coronary bypass grafts was studied in 12 patients subjected to aorto-coronary bypass surgery. Aorto-coronary bypass blood flow was determined by means of electromagnetic blood flowmetry. No change was observed in the bypass blood flow, either during or after intravenous somatostatin at doses of 100 microgram/h and 250 microgram/h. These findings suggest that somatostatin has no effect on coronary haemodynamics in man.
D000368:Aged; D000758:Anesthesia; D001794:Blood Pressure / Q000187:drug effects; D001026:Coronary Artery Bypass; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000601:surgery; D006801:Humans; D007275:Injections, Intravenous; D007387:Internal Mammary-Coronary Artery Anastomosis; D008875:Middle Aged; D013004:Somatostatin / Q000008:administration & dosage*; D014655:Vascular Resistance / Q000187:drug effects
D013004:Somatostatin