gamma-Glutamyltransferase in glomeruli and tubules of rat kidney cortex: effect of experimental diabetes.
A significant and reproducible fraction of kidney cortex gamma-glutamyltransferase (EC 2.3.2.2) activity has been found associated with isolated glomeruli, the specific activity was approximately half that of proximal tubules. The gamma-glutamyltransferase activity of both glomeruli and tubules was decreased, to about 50--60% of the control value, in the alloxan-diabetic group. The possible functions of gamma-glutamyltransferase in kidney glomeruli are discussed.
D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D007672:Kidney Cortex / Q000201:enzymology; D007678:Kidney Glomerulus / Q000201:enzymology*; D007684:Kidney Tubules / Q000201:enzymology*; D007687:Kidney Tubules, Proximal / Q000201:enzymology; D008297:Male; D051381:Rats; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D000496:Alloxan; D005723:gamma-Glutamyltransferase