[Enzymatic phenotype of preneoplastic islands induced in the rat liver by diethylnitrosamine].
Diethylnitrosamine was injected to Sprague-Dawley rats after a partial hepatectomy, and enzyme histochemistry analysis was made after 35 weeks in the preneoplastic liver. The areas and volumes of the induced enzyme-deficient islands were calculated for glucose-6-triphosphatase, adenosine triphosphatase, and 5'-nucleotidase. The preneoplastic enzyme-deficient zones showed also an increased incorporation of tritiated thymidine.
D015720:5'-Nucleotidase; D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D004052:Diethylnitrosamine; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D008114:Liver Neoplasms, Experimental / Q000201:enzymology*; D008297:Male; D009708:Nucleotidases / Q000378:metabolism*; D011230:Precancerous Conditions / Q000139:chemically induced / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains
D004052:Diethylnitrosamine; D009708:Nucleotidases; D015720:5'-Nucleotidase; D005952:Glucose-6-Phosphatase; D000251:Adenosine Triphosphatases
Fenotipo enzimático de islotes preneoplásicos inducidos en hígado de rata con dietilnitrosamina.