title: The low-resolution structure of human muscle aldolase.
abstract: The three-dimensional structure of human muscle aldolase has been solved at 5 A resolution with the use of two isomorphous heavy atom derivatives. The enzyme's four subunits are arranged about three mutually perpendicular intersecting twofold axes to form a compact spherical molecule. The subunit boundaries are clearly defined but a possible domain structure is not apparent in this preliminary electron density map.
mesh_terms: D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D005634:Fructose-Bisphosphate Aldolase; D006801:Humans; D046911:Macromolecular Substances; D008958:Models, Molecular; D009132:Muscles / Q000201:enzymology*; D011487:Protein Conformation; D014961:X-Ray Diffraction
chemical_list: D046911:Macromolecular Substances; D005634:Fructose-Bisphosphate Aldolase