Is there autonomic impairment in congestive (dilated) cardiomyopathy?
Autonomic function was investigated in patients with congestive (dilated) cardiomyopathy and compared with that in controls. Heart-rate and blood-pressure were recorded during physiological and pharmacological interventions and plasma noradrenaline concentration was measured at rest and when the physiological interventions produced a peak response. The results indicate that even at an early (pre-failure) stage of the disease parasympathetic function is impaired but no significant increase in sympathetic activity occurs at this stage.
D001341:Autonomic Nervous System / Q000503:physiopathology*; D009202:Cardiomyopathies / Q000503:physiopathology*; D006321:Heart / Q000294:innervation; D006333:Heart Failure / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D013564:Sympathetic Nervous System / Q000503:physiopathology; D013599:Systole; D014655:Vascular Resistance