Detection of pX proteins in human T-cell leukemia virus (HTLV)-infected cells by using antibody against peptide deduced from sequences of X-IV DNA of HTLV-I and Xc DNA of HTLV-II proviruses.
A 41-kilodalton protein was detected in four human T-cell leukemia virus type I (HTLV-I)-infected cell lines, a 68-kilodalton glycoprotein in MT-2 cells, and a 38-kilodalton protein in an HTLV-II-infected cell line by using antibody against a synthetic dodecapeptide, a portion of the polypeptide deduced from the nucleotide sequence of the X regions of HTLVs.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D001483:Base Sequence; D002460:Cell Line; D004279:DNA, Viral; D017977:Deltaretrovirus / Q000235:genetics*; D006801:Humans; D007114:Immunization; D007938:Leukemia / Q000378:metabolism*; D008970:Molecular Weight; D010455:Peptides / Q000276:immunology*; D011817:Rabbits; D012192:Retroviridae Infections / Q000378:metabolism*; D015534:Trans-Activators; D014764:Viral Proteins / Q000032:analysis*
D000914:Antibodies, Viral; D004279:DNA, Viral; D010455:Peptides; D015534:Trans-Activators; D014764:Viral Proteins