Synchronous Hodgkin's disease in monozygotic twins.
Identical Hodgkin's disease (HD) in monozygotic twins is presented together with a review of five previously reported pairs. The 12 reported cases of concordant HD in monozygotic twins had three characteristic features: a younger age than HD patients in general, a short interval between the onset of the disease in the two twins, and a similar histologic pattern in both twins. These rare cases may suggest that genetic and environmental factors are responsible for the occurrence of HD.
D000328:Adult; D004200:Diseases in Twins; D005260:Female; D006689:Hodgkin Disease / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D011247:Pregnancy; D013997:Time Factors; D014430:Twins, Monozygotic