title: The filter cigarette and coronary heart disease: the Framingham study.
abstract: Long-term follow-up of the Framingham cohort for coronary heart disease (CHD) end-points has made it possible to test the hypothesis that those who smoke filter cigarettes are less likely to get clinical manifestations of CHD than those who smoke non-filter cigarettes. Men were classified at the 7th biennial examination (1963--64) according to whether they smoked filter or non-filter cigarettes. 58% of the cigarette-smoking men under age 55 at this examination smoked filter cigarettes. These men had slightly lower prior smoking exposure than smokers of non-filter cigarettes. Despite what seemed to be a favourable cigarette-smoking history, the filter-cigarette smokers did not have lower CHD incidence rates than non-filter smokers. This finding was unchanged even after multivariate logistic regression analysis to adjust for the slight differences in age, systolic blood pressure, and serum cholesterol between the two groups.
mesh_terms: D000328:Adult; D000368:Aged; D002248:Carbon Monoxide / Q000008:administration & dosage; D003327:Coronary Disease / Q000517:prevention & control*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005374:Filtration / Q000295:instrumentation; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008404:Massachusetts; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage; D012907:Smoking; D013638:Tars / Q000008:administration & dosage
chemical_list: D013638:Tars; D009538:Nicotine; D002248:Carbon Monoxide