[A bioregulator of lipid nature--a platelet activating factor (PAF)].
The review concerns metabolism, immunological and antihypertensive action of platelet activating factor (PAF), a bioregulator of lipid nature. Major synthetic approaches to PAF and its analogues are described. The effects of structural modification on the physiological activity of PAF are considered.
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism; D001794:Blood Pressure; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D010972:Platelet Activating Factor / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism / Q000502:physiology*; D011453:Prostaglandins / Q000096:biosynthesis; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D007473:Ion Channels; D010972:Platelet Activating Factor; D011453:Prostaglandins
Bioreguliator lipidnoĭ prirody--faktor aktivatsii trombotsitov (PAF).