Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I.
A protein p40x was identified as a product encoded by frame IV in the pX region of human T-cell leukemia virus type I. Sera from patients with adult T-cell leukemia contained antibodies against p40x, indicating its expression in vivo. The occurrence of splicing to form pX mRNA is proposed and the possible significance of p40x is discussed.
D001483:Base Sequence; D003062:Codon; D017977:Deltaretrovirus / Q000235:genetics*; D006801:Humans; D007938:Leukemia / Q000235:genetics; D009857:Oncogenes; D015534:Trans-Activators; D014764:Viral Proteins / Q000032:analysis*; D014779:Virus Replication
D003062:Codon; D015534:Trans-Activators; D014764:Viral Proteins