Techniques of administration of metered-dose aerosolized drugs in asthmatic children.
The use of medications in metered-dose aerosol form in children with asthma has increased dramatically with the development of safer, inhaled beta 2-adrenergic agents and the inhaled corticosteroid, beclomethasone dipropionate. However, the most appropriate techniques of administration of these agents are presently unclear, and frequent inefficient use of these metered-dose inhalers results. We review the aerosol physiology literature to determine and recommend a most efficient inhalation technique for the use of these metered-dose aerosol devices.
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage* / Q000627:therapeutic use; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D001507:Beclomethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008176:Lung Volume Measurements; D012138:Respiratory Therapy; D014939:Work of Breathing
D000318:Adrenergic beta-Agonists; D000336:Aerosols; D001507:Beclomethasone