[The computerized electroencephalogram in evaluating the action of vasoactive and eumetabolic drugs in chronic cerebrovascular disorders].
In this work the authors estimated the effect, on cortical bioelectric activity, of two groups of drugs commonly used in the so-called chronic vascular cerebropathies. Through the computerized analysis of EEG the authors estimated vasoactive drugs (papaverine hydrochloride and xanthinol-nicotinate) and eumetabolic drugs (cytidin, uridin, cytidin + 1-glutamine association) in two groups of subjects (healthy volunteers and patients suffering from stabilized conditions of acute cerebrovascular insufficiency). As to vasoactive drugs, a different action of papaverine hydrochloride as compared to xanthinol-nicotinate was pointed out. Eumetabolic drugs showed an action of electroencephalographic activation statistically significant only if administered associated between them and with glutamine.
D000328:Adult; D000367:Age Factors; D000368:Aged; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000494:pharmacology; D001921:Brain / Q000187:drug effects; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D002908:Chronic Disease; D003562:Cytidine / Q000627:therapeutic use*; D004341:Drug Evaluation; D004569:Electroencephalography; D005973:Glutamine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000627:therapeutic use*; D013806:Theophylline / Q000031:analogs & derivatives*; D014529:Uridine / Q000627:therapeutic use*; D014971:Xanthinol Niacinate / Q000627:therapeutic use*
D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents; D005973:Glutamine; D003562:Cytidine; D014971:Xanthinol Niacinate; D013806:Theophylline; D010208:Papaverine; D014529:Uridine
L'elettroencefalogramma computerizzato nella valutazione dell'attività dei farmaci vasoattivi e eumetabolici nei disturbi cerebro-vascolari cronici.