title: Binding of rho factor to Escherichia coli RNA polymerase mediated by nusA protein.
abstract: The E. coli transcription termination factor rho binds specifically to purified nusA protein. Since nusA protein binds tightly to RNA polymerase, this provides a way of coupling rho to the elongating RNA polymerase complex through protein-protein interactions. These rho-nusA interactions may play a role in modulating rho action at certain terminators and could also be important in the action of antitermination factors such as lambda N protein.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D001426:Bacterial Proteins / Q000302:isolation & purification / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics; D007700:Kinetics; D011485:Protein Binding; D012234:Rho Factor / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D012234:Rho Factor; D014157:Transcription Factors; D012321:DNA-Directed RNA Polymerases; D000251:Adenosine Triphosphatases