Rotavirus shedding by newborn children.
We studied the shedding of rotavirus by newborn children in the nurseries of a large maternity hospital in Caracas, Venezuela, throughout the year 1982. Sixty-two (57%) of 108 children examined shed the virus within the first few days of life. Four (6%) of the 62 children who shed rotavirus had diarrhea but only one of them required oral rehydration therapy. The rotavirus specimens were identified as subgroup 2 in an ELISA subgrouping assay that employs monoclonal antibodies. Analysis of the RNA extracted from 52 of the samples by electrophoresis revealed a similar migration pattern in all the specimens; their identity was confirmed by crosshybridization analyses which revealed a strong degree of genomic homology among the strains studied.
D003967:Diarrhea / Q000209:etiology; D005243:Feces / Q000382:microbiology*; D005814:Genes, Viral; D006801:Humans; D007231:Infant, Newborn; D009693:Nucleic Acid Hybridization; D012330:RNA, Double-Stranded / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology; D014687:Venezuela
D012330:RNA, Double-Stranded; D012367:RNA, Viral