Opioid-induced feeding in the slug, Limax maximus.
Administration of the opioid agonist, morphine (1 and 10 mg X kg-1), resulted in significant, dose-dependent increases in the ingestive responses of food-deprived slugs, Limax maximus, and in the initiation of feeding in satiated animals. These effects could be blocked by the opiate antagonist, naloxone (1 mg kg-1), with naloxone by itself causing a significant decrease in the feeding of food-deprived slugs. These results suggest that opiates are involved in the control of the feeding behavior of Limax.
D000818:Animals; D004298:Dopamine / Q000502:physiology; D004723:Endorphins / Q000502:physiology*; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D008322:Mammals / Q000502:physiology; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D009424:Nervous System Physiological Phenomena; D012908:Snails / Q000502:physiology*; D009435:Synaptic Transmission
D004723:Endorphins; D009270:Naloxone; D009020:Morphine; D004298:Dopamine