The effect of beta-adrenergic stimulation and blockade on the efflux of PGE1-like material from the isolated perfused rabbit heart.
Prostaglandin (PG) release was measured from the isolated perfused rabbit heart. The effects of beta-adrenergic stimulation and blockade suggest that PG synthesis is regulated in part by adrenergic mechanisms.
D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D009206:Myocardium / Q000378:metabolism*; D011458:Prostaglandins E / Q000378:metabolism*; D011817:Rabbits; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D011458:Prostaglandins E; D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta