Selective decrease in immunoreactive somatostatin in rat intermediate pituitary lobe after stalk section.
Immunoreactive somatostatin is present in the intermediate pituitary lobe of the rat and, to a lesser extent, in the posterior lobe. Section of the pituitary stalk results in a marked (80%) decrease in somatostatin in the intermediate pituitary lobe, but no change in the peptide levels in the posterior lobe. These results indicate that a substantial part of intermediate lobe somatostatin is located in nerve fibers originated in the brain.
D000818:Animals; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D008297:Male; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D010904:Pituitary Gland, Posterior / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000378:metabolism*
D013004:Somatostatin