title: [The kidney, crossroad of the endocrines].
abstract: Connections between the kidney and the endocrine system are briefly reviewed. The kidney is a source of hormones and as such can be considered an endocrine organ. At the same time, it is a target organ for many hormones influencing renal hemodynamics or electrolyte transport across tubular epithelia. The kidney also influences the blood levels and the half-life of numerous hormones inasmuch these are degraded and excreted as they pass through it. Finally, the kidney is the site of antagonistic interactions between hormonal factors (kallikrein, prostaglandins), a fact which might explain the undesirable side effects of drugs such as the nonsteroidal antiinflammatory agents.
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D004231:Diuresis; D004702:Endocrine Glands / Q000378:metabolism*; D006207:Half-Life; D006439:Hemodynamics / Q000187:drug effects; D006728:Hormones / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D016030:Kidney Transplantation; D018377:Neurotransmitter Agents / Q000494:pharmacology; D011817:Rabbits; D012079:Renal Circulation / Q000187:drug effects
chemical_list: D006728:Hormones; D018377:Neurotransmitter Agents
vernacular_title: Le rein, carrefour endocrinien.