[Isolation of a peptide initiating burst activity in an identified neuron of Helix pomatia].
A peptide was isolated from the water-soluble fraction of brain extract of the snail (Helix pomatia). The peptide initiated or enhanced the bursting activity of the identified neuron RPa1. The effect of the peptide application was similar to the effect of the total water-soluble fraction. The action of the peptide on neuronal bursting activity was not identical to the action of other known peptides. It is suggested that under normal conditions the peptide is released from the presynaptic terminals of a nonidentified interneuron on the soma of RPa1 neuron initiating its bursting activity.
D000818:Animals; D004594:Electrophysiology; D005724:Ganglia / Q000032:analysis*; D006372:Helix, Snails / Q000032:analysis*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009419:Nerve Tissue Proteins / Q000302:isolation & purification* / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects*; D018377:Neurotransmitter Agents / Q000302:isolation & purification*; D013268:Stimulation, Chemical
D009419:Nerve Tissue Proteins; D018377:Neurotransmitter Agents
Vydelenie peptida, initsiruiushchego pachechnuiu aktivnost', u identifitsirovannogo neĭrona vinogradnoĭ ulitki.