[(Influence of somatostatin (SS-14) on early dumping reaction in patients after partial gastrectomy) ].
In seven patients suffering from early dumping syndrome after partial gastrectomy (Billroth II operation) an early dumping reaction was provoked by 100 g dextrose per os and the influence of somatostatin-14 (SS-14) infusion on clinical appearance of dumping syndrome was evaluated. SS-14 in contrast to the control trial resulted in total suppression of insulin release and slightly delayed and lowered increase of blood glucose which was not statistically significant, but with SS-14 there was no change in clinical symptoms of dumping reaction and compared to the control test no significant difference was found between the decrease of blood pressure, the increase of pulse frequency, the small increase of hematocrit and plasma free fatty acids.
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D002986:Clinical Trials as Topic; D004377:Dumping Syndrome / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D006400:Hematocrit; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D013004:Somatostatin / Q000494:pharmacology* / Q000627:therapeutic use
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D013004:Somatostatin
Einfluss von Somatostatin (SS-14) auf die Frühdumping-Reaktion von Patienten nach Billroth-II-Operation.