title: Lipopolysaccharide, capsule, and fimbriae as virulence factors among O1, O7, O16, O18, or O75 and K1, K5, or K100 Escherichia coli.
abstract: K1, K5, and K100 Escherichia coli isolates of the lipopolysaccharide antigen types O1, O7, O16, O18, or O75, which had formerly been assigned to clonal groupings were compared with K? E. coli isolates and with laboratory-derived mutants defective in capsule or lipopolysaccharide synthesis. The amount of K1 capsule, the length distribution of the lipopolysaccharide, and the expression of type I and P fimbriae were determined. The clonal groupings were uniform with regard to these properties within each group but different from each other. Many of the K? strains differed from the clonal representatives. The results are interpreted with regard to the different diseases caused by each of these bacterial groups.
mesh_terms: D002462:Cell Membrane / Q000648:ultrastructure; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity* / Q000648:ultrastructure; D010861:Fimbriae, Bacterial / Q000648:ultrastructure*; D008070:Lipopolysaccharides / Q000302:isolation & purification*; D008563:Membrane Lipids / Q000302:isolation & purification; D008565:Membrane Proteins / Q000032:analysis; D009154:Mutation; D010743:Phospholipids / Q000302:isolation & purification; D012703:Serotyping; D013045:Species Specificity; D014774:Virulence
chemical_list: D008070:Lipopolysaccharides; D008563:Membrane Lipids; D008565:Membrane Proteins; D010743:Phospholipids