[Demonstration of the virus of hemorrhagic fever with renal syndrome in the organs of rodents from natural foci of the infection in the USSR and the serodiagnosis of the diseases].
An indirect fluorescent antibody test (IFAT) and an enzyme-immunological test (ELISA) were used for the detection of HFRS virus in organs of rodents from HFRS foci in the USSR. The virus was found in 115 out of 1120 bank voles, 9 out of 92 redbacked voles, and 2 field voles examined. Spontaneous infection-rate of bank voles in population varied from 1.3 to 100% correlating with the epidemiological situation in foci. IFAT and ELISA were successfully used for serodiagnosis of HFRS. Examinations of 335 paired sera from 157 patients by the IFAT demonstrated seroconversion. Retrospective diagnosis and diagnosis of subclinical forms of the disease were also made.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D003289:Convalescence; D004197:Disease Reservoirs; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006476:Orthohantavirus / Q000276:immunology / Q000302:isolation & purification*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D012328:RNA Viruses / Q000302:isolation & purification*; D012377:Rodentia / Q000382:microbiology*; D012698:Serologic Tests / Q000379:methods; D014586:USSR
D000956:Antigens, Viral
Indikatsiia virusa gemorragicheskoĭ likhoradki s pochechnym sindromom v organakh gryzunov iz prirodnykh ochagov infektsii v SSSR i serodiagnostika zabolevaniĭ.