Late allergic reactions: the skin and the lung.
The late allergic response appears to be simply a sequel of an IgE-mediated mast cell-dependent allergic reaction which has a greater inflammatory component. Late responses in the skin and the bronchi share many similarities. Pharmacologic modification of the late allergic response is especially important because these reactions may be more severe and prolonged than immediate allergic reactions.
D000328:Adult; D005260:Female; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D006635:Histamine H2 Antagonists / Q000494:pharmacology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology; D008168:Lung / Q000187:drug effects / Q000276:immunology*; D008297:Male; D008407:Mast Cells / Q000276:immunology; D011058:Pollen / Q000276:immunology*; D012867:Skin / Q000187:drug effects / Q000276:immunology*
D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; D007073:Immunoglobulin E