title: Allergic rhinitis and conjunctivitis. Help for the weeping nose and eyes.
abstract: Both the eyes and the nose are in constant contact with the external environment and thus are common targets for immune-mediated disease. Progress in understanding the pathophysiology of allergic nasal and ocular disease has greatly enhanced the approach to therapy. Chronic rhinitis may be caused by a variety of immunologic and nonimmunologic mechanisms. Allergic and nonallergic factors often coexist, which complicates diagnosis and therapy. In external ocular disorders, both IgE- and IgG-mediated mechanisms may be involved. Elucidation of these mechanisms will be important in improving diagnosis and in facilitating development of new therapeutic modalities.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D003231:Conjunctivitis / Q000276:immunology / Q000628:therapy*; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology / Q000628:therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy*; D013566:Sympathomimetics / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D006634:Histamine H1 Antagonists; D007074:Immunoglobulin G; D013566:Sympathomimetics; D007073:Immunoglobulin E