Asthma therapy. Advantages and limitations of various approaches.
The physician who understands the various physiologic mechanisms that result in bronchospasm can choose the appropriate management approach. Recommended initial outpatient treatment of sporadic asthma consists of administration of an inhaled beta 2 agent, followed as necessary by a systemic beta 2 agent, a long-acting theophylline preparation, cromolyn, and inhaled ipratropium. Chronic steroid therapy should be used only after a trial of combination therapy with the foregoing drugs, and the daily dose of steroids should be minimized by use of a beclomethasone inhaler. Treatment of acute attacks depends on their chronicity and severity and on the medications the patient has already taken.
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004205:Cromolyn Sodium / Q000627:therapeutic use; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use; D007665:Ketotifen / Q000627:therapeutic use; D013806:Theophylline / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D002121:Calcium Channel Blockers; D013806:Theophylline; D009241:Ipratropium; D004205:Cromolyn Sodium; D007665:Ketotifen