Adrenergic receptors in the urethra and prostate of the horse.
The presence and types of alpha and beta adrenergic receptors in the urethra and prostate of the horse were studied in vitro using adrenergic agonist and antagonist drugs. The existence of these receptors was shown. This finding was based on the observation that the contractile action was mediated by adrenergic receptors of alpha-1 type, although in the prostate alpha-2 type receptors also participated. Relaxation in both tissues was controlled by receptors of the beta-2 type.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000818:Animals; D001381:Azepines / Q000494:pharmacology; D004347:Drug Interactions; D006736:Horses / Q000502:physiology*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology; D010643:Phenoxybenzamine / Q000494:pharmacology; D010656:Phenylephrine / Q000494:pharmacology; D011224:Prazosin / Q000494:pharmacology; D011467:Prostate / Q000032:analysis*; D011942:Receptors, Adrenergic, alpha / Q000032:analysis*; D011943:Receptors, Adrenergic, beta / Q000032:analysis*; D014521:Urethra / Q000032:analysis*; D015016:Yohimbine / Q000494:pharmacology
D000316:Adrenergic alpha-Agonists; D001381:Azepines; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D010643:Phenoxybenzamine; D010656:Phenylephrine; D015016:Yohimbine; C024763:talipexole; D009638:Norepinephrine; D011224:Prazosin