Naloxone-induced reduction of schizophrenic symptoms.
A schizophrenic patient was repeatedly treated with intravenous naloxone 0.04 mg or saline in a double-blind design. The Comprehensive Psychopathological Rating Scale was used to quantify the symptoms before and after each injection. Naloxone significantly reduced the symptoms temporarily, whereas saline was without effect.
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009270:Naloxone / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales; D006435:Renal Dialysis; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
D014150:Antipsychotic Agents; D009270:Naloxone