title: [Diagnosis and treatment of Wilms' tumor].
abstract: Recent advances in the diagnosis and treatment of Wilms' tumor are reviewed. Our study disclosed that principal clinical and pathological features of Wilms' tumor are as follows: (1) It occurs in young infants and children under 5 years of age; (2) It is frequently associated with other congenital anomalies; (3) Deletion of a portion of short arm of chromosome 11 can be closely related to the tumor genesis of nephroblastoma; (4) The occurrence of distant metastases is rare at diagnosis; (5) Differential diagnosis between Wilms' tumor and neuroblastoma is occasionally quite difficult; (6) There is no good tumor marker specific to Wilms' tumor; and (7) Two-year survival rate is about 90% at present.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003456:Cryptorchidism / Q000150:complications / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis*; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014513:Ureter / Q000002:abnormalities; D009396:Wilms Tumor / Q000150:complications / Q000175:diagnosis* / Q000628:therapy