Physiological mechanism of toxic action of DDT and endrin in two euryhaline freshwater fishes, Anguilla vulgaris and Mugil cephalus.
RBC counts, Ht value and Hb content in both species exposed to DDT and endrin concentrations were not significantly different from those of controls. WBC counts in both species exposed to the two pesticides for 96 hr decreased significantly at different concentrations. The variance ratios of cations and anions were consistently more concentrated in the serum of DDT- and endrin-exposed fishes. Serum cholesterol was sharply elevated in all the lots exposed to pesticides. Exposure to sublethal concentrations of DDT and endrin impaired liver function, as evidenced by the transfer of major cations from hepatic tissue to the serum and by elevated serum cholesterol.
D000818:Animals; D001773:Blood Cells / Q000187:drug effects; D002118:Calcium / Q000097:blood; D002712:Chlorides / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003634:DDT / Q000633:toxicity*; D004732:Endrin / Q000633:toxicity*; D005399:Fishes / Q000502:physiology*; D006400:Hematocrit; D008099:Liver / Q000187:drug effects; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood
D002712:Chlorides; D002784:Cholesterol; D012964:Sodium; D003634:DDT; D004732:Endrin; D011188:Potassium; D002118:Calcium