[Comparative study of the effect of lorazepam and tiapride on memorizing capacities of patients over 60 years of age].
Our purpose was to investigate the action on memory disorders of patients over sixty years of age of a well tolerated sedative neuroleptic, tiapride, and of a short-half-life benzodiazepine, lorazepam. Thirty subjects divided into two groups were entered in a three week trial. The product's effect on both anterograde memory and remote memory was assessed by the simple memory test used. Statistical conclusions show that tiapride is very significantly superior to lorazepam in every studied criterion, with disinhibition and stimulation of vigilance. These hypotheses need to be confirmed.
D000368:Aged; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001143:Arousal / Q000187:drug effects; D001549:Benzamides / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects*; D008875:Middle Aged; D013976:Tiapamil Hydrochloride / Q000494:pharmacology*
D014151:Anti-Anxiety Agents; D001549:Benzamides; D008140:Lorazepam; D013976:Tiapamil Hydrochloride
Etude comparative de l'action du lorazepam et du tiapride sur les capacités mnésiques du sujet âgé de plus de soixante ans.