Soft tissue potassium, magnesium, sodium and ash contents throughout the life span of highly inbred rats.
K, Mg, Na and ash contents were determined in nine tissues from short-lived Fischer rats at ages ranging from 1-21 months and from longer-lived A X C rats ranging from 1-28 months. K and Mg generally declined with aging in the tissues of both rat strains with higher rates of decline occurring in the shorter-lived Fischer rats. Na showed no consistent, strain-specific changes, but the majority of observed changes were age-related declines. Tissue ash contents generally declined during aging with the longer-lived A X C rats showing larger decreases.
D000375:Aging; D000818:Animals; D005260:Female; D008017:Life Expectancy; D008274:Magnesium / Q000032:analysis*; D008903:Minerals / Q000032:analysis*; D011188:Potassium / Q000032:analysis*; D051381:Rats; D011912:Rats, Inbred ACI; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains / Q000378:metabolism*; D012964:Sodium / Q000032:analysis*; D013045:Species Specificity
D008903:Minerals; D012964:Sodium; D008274:Magnesium; D011188:Potassium