Glutamate uptake into cerebral cortex slices is reduced in the presence of a gamma-glutamyl transpeptidase inhibitor.
The uptake of L-glutamic acid into brain cortex slices of mice of different age was studied. The results suggest that GGT contributes to the transport of L-glutamic acid into the brain.
D000375:Aging; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D001881:Borates / Q000494:pharmacology; D002540:Cerebral Cortex / Q000378:metabolism*; D005971:Glutamates / Q000378:metabolism*; D018698:Glutamic Acid; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012694:Serine / Q000494:pharmacology; D012964:Sodium / Q000494:pharmacology; D005723:gamma-Glutamyltransferase / Q000037:antagonists & inhibitors*
D001881:Borates; D005971:Glutamates; D018698:Glutamic Acid; D012694:Serine; D012964:Sodium; D005723:gamma-Glutamyltransferase