Acylases in plasma of hamsters with experimental hepatitis.
After the administration of D-galactosamine to golden Syrian hamsters, a rapid but short-lived increase in acylase I and cobalt-activated (AA-Co) activity was noted in the blood plasma, but not in the liver. In the plasma of control hamsters, only form 2 AA-Co was identified, but during experimental hepatitis, the appearance of form 1 was observed. Only form 2 hamster enzyme is strongly inhibited by alpha-hydroxyisocaproil-tyrosine and reacts with antihuman form 2 antibody.
D000410:Alanine Transaminase / Q000097:blood; D000581:Amidohydrolases / Q000097:blood; D000626:Aminopeptidases / Q000097:blood* / Q000378:metabolism; D000818:Animals; D006224:Cricetinae; D005688:Galactosamine / Q000494:pharmacology; D006505:Hepatitis / Q000201:enzymology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D008647:Mesocricetus; D005723:gamma-Glutamyltransferase / Q000097:blood
D005688:Galactosamine; D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase; D000626:Aminopeptidases; D000581:Amidohydrolases; C019665:amidase