Immunohistochemical demonstration of serotonin in nerves supplying human cerebral and mesenteric blood-vessels. Some speculations about their involvement in vascular disorders.
Serotonin (5-hydroxytryptamine, 5-HT) can produce vasoconstriction or vasodilatation and has been implicated in the pathogenesis of many vascular disorders. Nerves containing 5-HT were demonstrated by immunofluorescence histochemistry in fetal cerebral and mesenteric blood-vessels.
D002536:Cerebral Arteries / Q000294:innervation*; D005260:Female; D005333:Fetus; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008638:Mesenteric Arteries / Q000294:innervation*; D009412:Nerve Fibers / Q000032:analysis*; D012701:Serotonin / Q000032:analysis* / Q000502:physiology; D014652:Vascular Diseases / Q000503:physiopathology
D012701:Serotonin