Comparison of in vitro potencies in pharmacological and binding assays after inhibition of peptidases reveals that dynorphin (1-9) is a potent kappa-agonist.
D000818:Animals; D001923:Brain Chemistry; D004357:Drug Synergism; D004399:Dynorphins; D004723:Endorphins / Q000494:pharmacology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D009132:Muscles / Q000187:drug effects; D009197:Myenteric Plexus / Q000187:drug effects; D009294:Narcotics / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D014649:Vas Deferens / Q000187:drug effects
D004723:Endorphins; D009294:Narcotics; D011480:Protease Inhibitors; D004399:Dynorphins