title: Environmental and human isolates of Vibrio cholerae and Vibrio parahaemolyticus produce a Shigella dysenteriae 1 (Shiga)-like cytotoxin.
abstract: Some strains of Vibrio parahaemolyticus, Vibrio cholerae, and non-O1 V cholerae produce a bacterial-cell-associated, heat-stable material that is cytotoxic for hela cells. Cytotoxicity is completely neutralised by antibody to purified Shigella dysenteriae 1 (Shiga) toxin but not by antibody to purified cholera toxin.
mesh_terms: D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000276:immunology; D002771:Cholera / Q000382:microbiology; D002772:Cholera Toxin / Q000096:biosynthesis; D003429:Cross Reactions; D004405:Dysentery, Bacillary / Q000382:microbiology; D006367:HeLa Cells; D006801:Humans; D009500:Neutralization Tests; D022603:Shiga Toxins; D012762:Shigella dysenteriae / Q000276:immunology / Q000378:metabolism*; D014734:Vibrio cholerae / Q000302:isolation & purification / Q000378:metabolism*; D014736:Vibrio parahaemolyticus / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D001427:Bacterial Toxins; D022603:Shiga Toxins; D002772:Cholera Toxin