Depletion of glutathione by inhibition of biosynthesis.
D000818:Animals; D019328:Buthionine Sulfoximine; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D005721:Glutamate-Cysteine Ligase / Q000037:antagonists & inhibitors; D005978:Glutathione / Q000096:biosynthesis*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008717:Methionine Sulfoximine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D009132:Muscles / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism
D008717:Methionine Sulfoximine; D019328:Buthionine Sulfoximine; D005721:Glutamate-Cysteine Ligase; D005978:Glutathione