title: Human colonic pharmacology.
abstract: This paper briefly reviews human colonic innervation, and the effects of acetylcholine, noradrenaline, histamine, 5-hydroxytryptamine, polypeptides and prostaglandins. It discusses the actions of drugs used to treat disorders of colonic motility and fluid transport, and the possible ways they may exert their effects.
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000930:Antidiarrheals / Q000494:pharmacology; D002400:Cathartics / Q000494:pharmacology; D003106:Colon / Q000187:drug effects* / Q000294:innervation; D005769:Gastrointestinal Motility / Q000187:drug effects; D006633:Histamine Antagonists / Q000494:pharmacology; D006801:Humans; D010276:Parasympatholytics / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology; D011453:Prostaglandins / Q000494:pharmacology; D012702:Serotonin Antagonists / Q000494:pharmacology
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000930:Antidiarrheals; D002400:Cathartics; D006633:Histamine Antagonists; D010276:Parasympatholytics; D010455:Peptides; D011453:Prostaglandins; D012702:Serotonin Antagonists