title: Phosphodiesterase dysfunction, cyclic GMP accumulation, and visual cell degeneration in early-onset inherited blindness.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000172:deficiency* / Q000378:metabolism; D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000172:deficiency* / Q000378:metabolism; D000818:Animals; D002417:Cattle; D006152:Cyclic GMP / Q000378:metabolism*; D004283:Dog Diseases / Q000235:genetics; D004285:Dogs; D006160:Guanosine Triphosphate / Q000502:physiology; D006162:Guanylate Cyclase / Q000032:analysis / Q000378:metabolism; D006868:Hydrolysis; D051379:Mice; D008817:Mice, Mutant Strains; D010750:Phosphoproteins / Q000378:metabolism; D010786:Photoreceptor Cells / Q000201:enzymology*; D011817:Rabbits; D051381:Rats; D012160:Retina / Q000378:metabolism; D012162:Retinal Degeneration / Q000235:genetics* / Q000378:metabolism / Q000662:veterinary; D012374:Rod Cell Outer Segment / Q000201:enzymology*; D012376:Rodent Diseases / Q000235:genetics
chemical_list: D010750:Phosphoproteins; D006160:Guanosine Triphosphate; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D006162:Guanylate Cyclase; D006152:Cyclic GMP