Estimation of N-amino-N,N-dimethylaminoethanol, choline and their acetate esters by gas chromatography mass spectrometry.
A method is described for measurement of choline, N-aminodeanol, and their acetyl esters by gas chromatography mass spectrometry. The preparation of N-aminodeanol and its isotopic variants is also described. This method allows a thorough quantitative analysis of the replacement of true with false neurotransmitter in biological preparations.
D000109:Acetylcholine / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D002794:Choline / Q000031:analogs & derivatives* / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D018377:Neurotransmitter Agents / Q000032:analysis
D018377:Neurotransmitter Agents; C038146:N-amino-N,N-dimethylaminoethanol; C038147:O-acetyl-N-amino-N,N-dimethylaminoethanol; D002794:Choline; D000109:Acetylcholine