[Effect of fluoride and insulin on cation-dependent ATPase activity of the enterocytes during threonine absorption].
Absorption of threonine was accompanied by a distinct increase in total activity of Mg2+- and Na+, K+-ATPases in rat small intestine. Sodium fluoride inhibited completely the Na+, K+-ATPase activity. After administration of insulin, activity of Na+, K+-ATPase was increased 2-fold without loading with threonine, and it was increased 3.3-fold in the amino acid loading. Sodium fluoride activated Mg2+-ATPase, insulin did not affect the enzyme activity but the hormone decreased partially the inhibitory effect of sodium fluoride on Na+, K+-ATPase.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase; D005459:Fluorides / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology*; D007408:Intestinal Absorption / Q000187:drug effects*; D007421:Intestine, Small / Q000187:drug effects* / Q000201:enzymology; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013912:Threonine / Q000378:metabolism*
D007328:Insulin; D013912:Threonine; D000251:Adenosine Triphosphatases; D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase; D005459:Fluorides
Vliianie ftorida i insulina na aktivnost' kationzavisimykh ATF-az énterotsitov pri vsasyvanii treonina.