title: Large layer VI neurons of monkey striate cortex (Meynert cells) project to the superior colliculus.
abstract: After injections of the enzyme horseradish peroxidase (HRP) into the superior colliculus of macaque monkeys, labelled cells in the neocortex were found to be restricted to layer V in all areas except striate visual cortex. In striate visual cortex, cortico-tectal cells were found both in layer V and in layer VI. The labelled cells in the two layers belonged to morphologically different populations: those of layer V were the common pyramidal cells and those of layer VI were identified as solitary cells of Meynert. This finding may provide new insights into the physiology of the cortico-collicular pathways. It also shows that the striate area in primates differs, with respect to cortico-tectal laminar specificity, from other neocortex.
mesh_terms: D000818:Animals; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D008252:Macaca fascicularis; D008254:Macaca nemestrina; D009474:Neurons / Q000166:cytology*; D013477:Superior Colliculi / Q000166:cytology*; D014793:Visual Cortex / Q000166:cytology*
chemical_list: D006735:Horseradish Peroxidase