title: Conformational activation of the EF-Tu . GTPase activity. Stimulation of the 2'(3')-O-L-phenylalanyladenosine-promoted EF-Tu . GTPase upon binding of the tRNAPhe lacking the terminal adenosine residue.
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000378:metabolism; D000899:Aurodox / Q000494:pharmacology; D020963:GTP Phosphohydrolase-Linked Elongation Factors / Q000378:metabolism*; D007700:Kinetics; D010444:Peptide Elongation Factor Tu; D010445:Peptide Elongation Factors / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D011485:Protein Binding; D011487:Protein Conformation; D012346:RNA, Transfer, Amino Acyl / Q000235:genetics*; D013329:Structure-Activity Relationship
chemical_list: D010445:Peptide Elongation Factors; D012346:RNA, Transfer, Amino Acyl; D000899:Aurodox; C032877:2'-O-L-phenylalanyladenosine; C032878:3'-O-L-phenylalanyladenosine; D010744:Phosphoric Monoester Hydrolases; D020963:GTP Phosphohydrolase-Linked Elongation Factors; D010444:Peptide Elongation Factor Tu; D000241:Adenosine