title: Combination therapy--a review of clinical studies.
abstract: Nine papers which have specifically examined the effects of combining sympathomimetic bronchodilator therapy with ipratropium bromide in the treatment of patients with airflow obstruction are reviewed. The published evidence suggests that the use of combination therapy in the more elderly bronchitic patients is now justified, but that the case for routinely giving such treatment to younger asthmatic patients needs further evaluation before any definite recommendation can be made.
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000328:Adult; D001249:Asthma / Q000188:drug therapy; D001286:Atropine Derivatives / Q000627:therapeutic use*; D001991:Bronchitis / Q000188:drug therapy; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000188:drug therapy
chemical_list: D000318:Adrenergic beta-Agonists; D001286:Atropine Derivatives; D009241:Ipratropium