title: Intracellular Ca2+ activity during slow synaptic hyperpolarizations in Helix pomatia.
abstract: In the "bursting" cell RPal of Helix pomatia, intracellular Ca2+ activity increased during the slow synaptic hyperpolarization termed LLH. The Ca2+ increase had a double exponential time course and the kinetics provide evidence for an intracellularly located Ca2+ source. The Ca2+ wave could be mimicked by dopamine and inhibited by ergometrine. dB-cAMP also enhanced the Ca2+ activity. Intracellular K+ was measured during LLH. An appendix by J. D. C. Labmert demonstrates that a dominant mechanism underlying LLH is the increase of K+ permeability.
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000378:metabolism*; D003994:Bucladesine / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D004298:Dopamine / Q000494:pharmacology; D004566:Electrodes; D004594:Electrophysiology; D004874:Ergonovine / Q000494:pharmacology; D005475:Flupenthixol / Q000494:pharmacology; D006372:Helix, Snails / Q000502:physiology*; D007424:Intracellular Fluid / Q000378:metabolism*; D007700:Kinetics; D009474:Neurons / Q000502:physiology; D011188:Potassium / Q000378:metabolism; D013569:Synapses / Q000502:physiology*
chemical_list: D003994:Bucladesine; D005475:Flupenthixol; D011188:Potassium; D002118:Calcium; D004298:Dopamine; D004874:Ergonovine