Evaluation of glycine as an inactivator of glutaraldehyde.
Glycine was evaluated as an inactivator of the sporicidal activity of glutaraldehyde. Spores from glucose depleted cultures of Bacillus stearothermophilus grown in a chemically defined medium were used. When glycine is used as an inactivator  of glutaraldehyde, it lowers the pH value of the solution. Glycine 1% failed to inactivate 0.5% or higher concentrations of alkaline glutaraldehyde in sporicidal studies. If viable counts cannot be performed within the first hour after inactivation, the concentration of glycine should be at least 2% to inactivate effectively 2% alkaline glutaraldehyde.
D000447:Aldehydes / Q000037:antagonists & inhibitors*; D003470:Culture Media; D004202:Disinfectants / Q000037:antagonists & inhibitors*; D001411:Geobacillus stearothermophilus / Q000187:drug effects; D005947:Glucose; D005976:Glutaral / Q000037:antagonists & inhibitors*; D005998:Glycine / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D013171:Spores, Bacterial / Q000187:drug effects; D013997:Time Factors
D000447:Aldehydes; D003470:Culture Media; D004202:Disinfectants; D005947:Glucose; D005976:Glutaral; D005998:Glycine