[Transmission of excitation through the superior cervical ganglion at an early stage of postnatal development].
The action of hexonium, d-tubocurarine, phentolamine and atropine on synaptic transmission in the superior cervical ganglia of rabbit, cat and rat was studied at early postnatal stages (1-8 days after birth). It was shown that hexonium and d-tubocurarine (intravenous injection or addition to Kreb's solution) inhibit the transmission of excitation in the ganglia both in situ and in vitro. No difference was found in the action of phentolamine and atropine on synaptic transmission in the ganglia of newborn and adult animals. A conclusion is made that synaptic transmission in sympathetic ganglia at early postnatal stage is cholinergic.
D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001285:Atropine / Q000494:pharmacology; D002415:Cats; D005728:Ganglia, Sympathetic / Q000187:drug effects / Q000502:physiology*; D018738:Hexamethonium; D006584:Hexamethonium Compounds / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D009435:Synaptic Transmission / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology
D006584:Hexamethonium Compounds; D018738:Hexamethonium; D001285:Atropine; D000109:Acetylcholine; D014403:Tubocurarine; D010646:Phentolamine
Provedenie vozbuzhdeniia cherez verkhniĭ sheĭnyĭ gangliĭ na rannem étape postnatal'nogo razvitiia.