Sodium-ion dependence of glycine and lysine transport in chicken erythrocytes genetically selected for high and low leucine transport activity.
Amino acid transport was studied in two lines of chickens, one high and the other low uptake, selected for their ability to transport leucine into erythrocytes. On the basis of the number of mol of substrate transferred, medium Na+ was found to be more effective in stimulating glycine and lysine transport into high line cells than into low line cells. Glycine transport in both lines was stimulated by medium Na+ to a greater degree than was lysine transport. In the absence of medium Na+, glycine transport was not significantly different in the two lines. In the absence of medium Na+, lysine transport in the high line was about five-fold greater than in the low line. The transport differences between the lines are probably due to differences in several distinct genetic determinants.
D000818:Animals; D001692:Biological Transport; D002645:Chickens / Q000235:genetics* / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism*; D012964:Sodium / Q000494:pharmacology / Q000502:physiology*; D013268:Stimulation, Chemical
D012964:Sodium; D008239:Lysine; D005998:Glycine