Polyarteritis nodosa after HBsAg hepatitis in a patient undergoing hemodialysis: manifestation and response to therapy.
Polyarteritis nodosa developed in one of 34 patients undergoing long-term maintenance hemodialysis with persistent hepatitis B surface antigenemia. Exacerbation of the baseline hypertension and progressive peripheral neuropathy during the recovery phase of hepatitis B surface antigen hepatitis were the initial features. Poor response to aggressive corticosteroid and immunosuppressive therapy in this patient was in contrast to recent experience in patients undergoing long-term hemodialysis and the general population.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D006973:Hypertension / Q000150:complications; D009443:Neuritis / Q000150:complications; D010488:Polyarteritis Nodosa / Q000188:drug therapy / Q000209:etiology*; D006435:Renal Dialysis; D014657:Vasculitis / Q000188:drug therapy / Q000209:etiology
D000305:Adrenal Cortex Hormones; D006514:Hepatitis B Surface Antigens; D003520:Cyclophosphamide