title: Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening study group.
abstract: A mass screening system for the early detection by means of a vanillylmandelic acid test of neuroblastoma in 6-month-old infants in Japan has been developed in eight districts. 16 of the 281 939 infants screened by this test had neuroblastoma, equivalent to a very high incidence of 1 in 17 621. 15 of the 16 children with neuroblastoma are alive; the other child died 1 month after surgery. This mass screening system for neuroblastoma used in infancy can help to improve prognosis in infants with this malignant disorder.
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan; D008297:Male; D008403:Mass Screening; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000453:epidemiology; D009447:Neuroblastoma / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D014642:Vanilmandelic Acid / Q000652:urine
chemical_list: D014642:Vanilmandelic Acid