Arginine vasotocin alters hamster pituitary LH and prolactin secretion in vitro.
1. Arginine vasotocin (AVT) stimulated the release of both luteinizing hormone (LH) and prolactin (PRL) from normal hamster (Mesocricetus auratus) anterior pituitary glands in a dose-dependent manner. 2. AVT significantly augmented the depressed level of PRL release from pituitaries of blind-pinealectomized animals. 3. LH release from the pituitaries of blinded hamsters was inhibited by AVT while FSH levels were unaffected.
D000818:Animals; D001766:Blindness / Q000503:physiopathology; D006224:Cricetinae; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D008647:Mesocricetus; D010870:Pineal Gland / Q000502:physiology; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism*; D014668:Vasotocin / Q000494:pharmacology*
D011388:Prolactin; D007986:Luteinizing Hormone; D014668:Vasotocin