title: Immunocytochemical localization of GABA neurons and dopamine neurons in the rat main and accessory olfactory bulbs.
abstract: Immunocytochemical localization of GABA neurons and dopamine neurons in the rat olfactory bulb was obtained with sheep antiserum to glutamate decarboxylase (GAD) and rabbit antiserum to tyrosine hydroxylase (TH). GAD-positive neurons include periglomerular cells, granule cells, superficial and deep short axon cells. TH-positive neurons represent periglomerular cells. Two-color immunocytochemistry shows that GABA and dopamine periglomerular cells are separate populations. The accessory olfactory bulb has rare dopamine cells and few superficial short axon cells. Radial gradients of GAD-immunostaining are evident in the main but not in the accessory olfactory bulb.
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000201:enzymology*; D004298:Dopamine / Q000378:metabolism*; D005968:Glutamate Decarboxylase / Q000378:metabolism; D007124:Immunoenzyme Techniques; D008854:Microscopy, Electron; D009415:Nerve Net / Q000201:enzymology; D009474:Neurons / Q000145:classification / Q000201:enzymology; D009830:Olfactory Bulb / Q000201:enzymology*; D009832:Olfactory Nerve / Q000201:enzymology; D009833:Olfactory Pathways / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000201:enzymology; D009435:Synaptic Transmission; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005680:gamma-Aminobutyric Acid; D014446:Tyrosine 3-Monooxygenase; D005968:Glutamate Decarboxylase; D004298:Dopamine