A comparison of the accumulation and protein binding of environmental cadmium in the gills, kidney and liver of rainbow trout (Salmo gairdneri Richardson).
Rainbow trout were exposed to cadmium in their aquarium water for different lengths of time and at different concentrations. More than 99% of the total body loads accumulated under all such conditions of exposure was found in the liver, kidney and gills. Comparison of the metal-binding proteins in these organs indicated that two low mol. wt proteins sequestered the cadmium while zinc was bound to metallothionein. Cadmium was not found in association with metallothionein unless artificially high concentrations were introduced either by intraperitoneal injection of the fish or by dialysis of tissue extracts in vitro.
D000818:Animals; D002104:Cadmium / Q000378:metabolism* / Q000633:toxicity; D005880:Gills / Q000187:drug effects / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D011485:Protein Binding; D012487:Salmonidae / Q000378:metabolism*; D014018:Tissue Distribution; D014337:Trout / Q000378:metabolism*
D002104:Cadmium