title: Thyroidal iodine and thyroglobulin in hibernating and active Richardson's ground squirrels Spermophilus richardsoni.
abstract: Thyroidal iodine, protein and thyroglobulin (TG) were investigated in a hibernator, Spermophilus richardsoni, sampled in the field and from laboratory-held winter colonies. In field animals, thyroidal iodine and protein contents were similar at onset of hibernation and at terminal arousal. Iodine content was increased in laboratory-held animals, a function of alimentary supply, but no differences were observed between hibernators and non-hibernators. Density sucrose gradients showed that approx. 20% of the TG was present as the 12S precursor sub-unit. No variations in the iodine content, nor the iodoamino acid composition of the TG occurred as a function of hibernation.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001143:Arousal; D006605:Hibernation; D007454:Iodides / Q000378:metabolism; D007455:Iodine / Q000378:metabolism*; D009929:Organ Size; D011506:Proteins / Q000378:metabolism; D012589:Sciuridae / Q000378:metabolism*; D013954:Thyroglobulin / Q000378:metabolism*; D013961:Thyroid Gland / Q000033:anatomy & histology / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D007454:Iodides; D011506:Proteins; D013954:Thyroglobulin; D007455:Iodine