title: [Experience in using glutamic acid electrophoresis in the early treatment of craniocerebral injuries].
abstract: Endonasal electrophoresis with alpha-glutamic acid was used in 76 patients with severe craniocerebral injury. The result was good in 24 (38%) and satisfactory in 40 (55%) patients. Thus, a positive result of treatment was obtained in 88% of cases, which was confirmed by electrophysiological and neuropsychological studies. The method produced the greatest effect on the patients' psychic status: 74% of all disorders of higher psychic functions, mainly memory, were restored on the average by the end of treatment. Good tolerance of electrophoresis and its efficacy in the early period after severe injury, i. e. in the first month, were established. Contraindications for treatment were defined more precisely. Since the method is simple and does not call for special conditions, it may be widely used in any medical establishment equipped with galvanization apparatuses.
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D000368:Aged; D000628:Aminophylline / Q000008:administration & dosage / Q000627:therapeutic use; D001930:Brain Injuries / Q000188:drug therapy*; D004569:Electroencephalography; D004586:Electrophoresis; D004834:Epilepsy, Post-Traumatic / Q000517:prevention & control; D005971:Glutamates / Q000008:administration & dosage* / Q000627:therapeutic use; D018698:Glutamic Acid; D006801:Humans; D008875:Middle Aged; D009069:Movement Disorders / Q000188:drug therapy; D019965:Neurocognitive Disorders / Q000188:drug therapy; D012893:Sleep Wake Disorders / Q000188:drug therapy
chemical_list: D005971:Glutamates; D000628:Aminophylline; D018698:Glutamic Acid
vernacular_title: Opyt primeneniia élektroforeza s gliutaminovoĭ kislotoĭ v terapii rannego perioda tiazheloĭ cherepno-mozgovoĭ travmy.