[Functional and morphological status of the gastric mucosa mast cells on the administration of dimedrol and suprastin].
Histochemical and morphometric analysis of mast cells of the gastric and duodenal mucosa of rats given dyphenhydramine and suprastin for a long period of time (up to 45 days) revealed an increase in their functional activity that manifested in the enhancement of the processes of neoformation and maturation of juvenile mast cells and in the increased break down of mature cellular forms.
D000818:Animals; D004155:Diphenhydramine / Q000494:pharmacology*; D004386:Duodenum / Q000187:drug effects; D005029:Ethylenediamines / Q000494:pharmacology*; D005753:Gastric Mucosa / Q000187:drug effects*; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D007413:Intestinal Mucosa / Q000187:drug effects; D008297:Male; D008407:Mast Cells / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D005029:Ethylenediamines; D006634:Histamine H1 Antagonists; C004664:chloropyramine; D004155:Diphenhydramine
Issleovanie funktsional'no-morfologicheskogo sostoianiia tuchnykh kletok slizistoĭ obolochki zheludka pri vvedenii dimedrola i suprastina.