Changes in rat ventricular myosin in old age.
Myosin was isolated from rat ventricular myocardium, and its properties were compared in adult and very old animals. Ca2+ -ATPase activity of ventricular myosin was found to be lower in very old animals as compared with adult ones; K+ -ATPase activity, however, does not change with the aging process. Neither were there any differences between the two age groups in the pattern of ventricular light chains of myosin.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000375:Aging; D000818:Animals; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D027682:Cation Transport Proteins; D005260:Female; D006352:Heart Ventricles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D009218:Myosins / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D027682:Cation Transport Proteins; D000251:Adenosine Triphosphatases; C022761:potassium transporting ATPase; D009218:Myosins; D000252:Calcium-Transporting ATPases