Biliary lipids in ox and sheep.
1. The lipids of gallbladder bile from sheep are more concentrated than in ox (P less than 0.001). 2. More than 90% of bile acids in both species are conjugated. 3. Taurocholate predominates in sheep while glycocholate predominates in bovine gallbladder bile. 4. The concentration of free bile acids i.e. lithocholate and (deoxycholate + chenodeoxycholate) is higher in bovine than in sheep gallbladder bile (P less than 0.001). 5. The ratio of conjugated to free bile acids is greater in sheep than in bovine gallbladder bile (P less than 0.010). 6. The ratio of total conjugated dihydroxy to trihydroxy bile acids is greater in bovine than in sheep gallbladder bile (P less than 0.001). 7. The ratio of the tauroconjugates of dihydroxy to trihydroxybile acids is higher in bovine than in sheep gallbladder bile (P less than 0.001). 8. It is concluded that the high fibre content of the diet of the two species studied stimulates the liver to form bile acids and hence the low lithogenicity of bile observed.
D000818:Animals; D001646:Bile / Q000032:analysis*; D001647:Bile Acids and Salts / Q000032:analysis; D002417:Cattle; D008055:Lipids / Q000032:analysis*; D008297:Male; D012756:Sheep
D001647:Bile Acids and Salts; D008055:Lipids