Chronic continuous administration of neuroleptic drugs alters cerebral dopamine receptors and increases spontaneous dopaminergic action in the striatum.
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D001058:Apomorphine / Q000494:pharmacology; D003342:Corpus Striatum / Q000187:drug effects*; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects / Q000378:metabolism*; D013134:Spiperone / Q000378:metabolism; D014268:Trifluoperazine / Q000008:administration & dosage
D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D014268:Trifluoperazine; D013134:Spiperone; D001058:Apomorphine; D000109:Acetylcholine