Roles of 5-hydroxytryptamine and dopamine as neurotransmitters eliciting release of erythrophorotropic hormones in the fiddler crab, UCA pugilator.
This article reviews the endocrinological, pharmacological and biochemical evidence ascribing neurotransmitter roles for 5-hydroxytryptamine (5-HT, serotonin) in eliciting the release of red pigment-dispersing hormone (RPDH) and for dopamine (DA) in stimulating the release of red pigment-concentrating hormone (RPCH) in the fiddler crab, Uca pugilator. 5-HT produces red pigment dispersion in intact crabs, but only indirectly. Likewise, DA evokes red pigment concentration in vivo but it has no effect on red chromatophores (erythrophores) in isolated legs. The data obtained with 5-HT and DA agonists and antagonists on red pigment translocation in vivo and in vitro, are consistent with their neurotransmitter candidacies in evoking the release of these erythrophorotropic hormones.
D000818:Animals; D003386:Brachyura / Q000187:drug effects* / Q000502:physiology; D002856:Chromatophores / Q000187:drug effects*; D004298:Dopamine / Q000494:pharmacology*; D066298:In Vitro Techniques; D007447:Invertebrate Hormones / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D018377:Neurotransmitter Agents; D009842:Oligopeptides / Q000378:metabolism; D010455:Peptides / Q000494:pharmacology; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D012701:Serotonin / Q000494:pharmacology*
D007447:Invertebrate Hormones; D008996:Monoamine Oxidase Inhibitors; D018377:Neurotransmitter Agents; D009842:Oligopeptides; D010455:Peptides; D012701:Serotonin; C022059:red pigment-concentrating hormone; C027714:melanophore-dispersing hormone; D011761:Pyrrolidonecarboxylic Acid; D004298:Dopamine