Successful long-term use of a plasmapheresis reactor system in dogs with lymphoma.
The successful long-term use of asparaginase-glutaminase reactor in dogs with lymphoma is described. The limitations of the system consisting of an activation of enzymes leading to rapid neosynthesis of asparagine and glutamine are outlined. The possible beneficial effect of future combination therapy with amino acid analogues is discussed.
D000818:Animals; D001216:Asparagine / Q000097:blood; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D005971:Glutamates / Q000097:blood; D018698:Glutamic Acid; D005973:Glutamine / Q000097:blood; D007700:Kinetics; D008223:Lymphoma / Q000628:therapy* / Q000662:veterinary*; D010956:Plasmapheresis
D005971:Glutamates; D005973:Glutamine; D018698:Glutamic Acid; D001216:Asparagine