title: Conglutinin, immunoconglutinins and heterophile antibodies in the sera of apparently healthy moose (Alces alces) and caribou (Rangifer tarandus) in Quebec.
abstract: Serum samples from apparently healthy wild populations of moose and caribou in the province of Quebec, Canada were screened for the presence of conglutinin (K), immunoconglutinins (IKS) and heterophile antibodies. The conglutinating factor in moose and caribou sera was characterized utilizing the necessity of calcium ions for its reaction with sensitized sheep erythrocytes which had been alexinated with horse complement. The conglutinating substance in these animals did not require calcium ions for its activity. The conglutinating activity in both moose and caribou sera was characterized due to IKS as those present in sheep, dog and rabbit sera. Both moose and caribou had non-agglutinating type of heterophile antibodies. Their titres varied from 0 to 80. None of the animals tested had K in their blood. The titre of IKS varied from 0 to 640 with a mean value of 41 in moose, whereas it varied from 0 to 80 with a mean value of 18 in caribou. About 75% of all the animals in both the groups were positive for IKS. The specificity of IKS was demonstrated by the total removal of its activity on absorption with alexinated cells. Presence of IKS in these animals is suggestive of latent infection(s) possibly of bacterial, viral or parasitic origin.
mesh_terms: D000828:Animal Population Groups / Q000276:immunology*; D000818:Animals; D000835:Animals, Wild / Q000276:immunology*; D000910:Antibodies, Heterophile / Q000032:analysis*; D002020:Buffaloes / Q000276:immunology; D002417:Cattle / Q000276:immunology; D037222:Collectins; D003168:Complement Fixation Tests; D003670:Deer / Q000276:immunology*; D004492:Edetic Acid; D037561:Immunoconglutinins; D007136:Immunoglobulins / Q000032:analysis*; D012053:Reindeer / Q000276:immunology*; D012712:Serum Globulins / Q000032:analysis*
chemical_list: D000910:Antibodies, Heterophile; D037222:Collectins; D037561:Immunoconglutinins; D007136:Immunoglobulins; D012712:Serum Globulins; C024014:conglutinin; D004492:Edetic Acid