title: [Multiple endocrine adenopathy type IIb. 15-years' observation of a case].
abstract: MEA IIb is a combination of C-cell carcinoma of the thyroid, phaeochromocytoma, multiple neuromas and a marfanoid habitus. A hyperplasia of the parathyroid cannot be found in most of the patients with this variant of Sipple's syndrome. In a 30-year-old woman, a MEA IIb could be observed over 15 years. Although primary surgery of the C-cell-carcinoma was insufficient, metastases were not found following two more surgical interventions in spite of elevated serum calcitonin. A phaeochromocytoma was not found, too. The reported case is compared with the literature.
mesh_terms: D000328:Adult; D002116:Calcitonin / Q000097:blood; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000097:blood / Q000473:pathology* / Q000601:surgery; D013961:Thyroid Gland / Q000378:metabolism; D013997:Time Factors
chemical_list: D006728:Hormones; D002116:Calcitonin
vernacular_title: Multiple endokrine Adenopathie Typ IIb. Fallbeobachtung über 15 Jahre.