title: Bacterial invasion of pulpal dentin wall in vitro.
abstract: Instrumented root canals of extracted human teeth were inoculated with known pulpal bacterial isolates. The inoculated teeth were immersed in the appropriate culture media and incubated at 37 degrees C for varying periods. Streptococci multiplied in the root canals and invaded the radicular dentinal tubules. The extent of bacterial invasion was time-dependent. This experimental model of bacterial invasion was time-dependent. This experimental model may be useful in investigating the effect of intra-canal medicaments on microorganisms lodged in the pulpal dentin wall.
mesh_terms: D000328:Adult; D000368:Aged; D001419:Bacteria / Q000166:cytology*; D003782:Dental Pulp / Q000382:microbiology*; D003804:Dentin / Q000382:microbiology*; D013293:Enterococcus faecalis / Q000166:cytology; D006801:Humans; D008875:Middle Aged; D008954:Models, Biological; D010460:Peptococcus / Q000166:cytology; D001443:Prevotella melaninogenica / Q000166:cytology; D013298:Streptococcus sanguis / Q000166:cytology; D013997:Time Factors