title: [Alcoholism: enzyme diagnostic criteria of health and disease (experimental-theoretical aspect)].
abstract: Sixty-three patients with Stage I and II alcoholism and 31 healthy subjects were studied over 5-10 days for the serum activity of such enzymes as gamma-glutamyltransferase, aspartate aminotransferase and alanyl aminotransferase. It was established that determination of the activity of the serum enzymes together with the assessment of their activity fluctuations revealed by repeated analyses confirms in 70%-90% the diagnosis of alcoholism made conventionally on the basis of the symptomatological and history data.
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000175:diagnosis*; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase
vernacular_title: Alkoglizm: énzimodiagnosticheskie kriterii zdorov'ia i bolezni (éksperimental'no-teoreticheskiĭ aspekt).