title: On the binding of labelled saxitoxin to the squid giant axon.
abstract: Measurement of the maximum saturable binding capacity for 3H-labelled saxitoxin in well cleaned giant axons from Loligo forbesi gave a value of 290 +/- 65 (s.e.m.) binding sites per square micrometre of membrane. In samples of the fin nerve the total saturable uptake was 12.4 +/- 2.4 fmol mg-1 wet mass, corresponding to 94 sites per square micrometre for fibres whose mean diameter after fixation and embedding was estimated as 16 micron.
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism*; D001665:Binding Sites; D049832:Decapodiformes; D012530:Saxitoxin / Q000378:metabolism*
chemical_list: D012530:Saxitoxin