[Mechanisms of stomach secretion in dogs infused with histamine, carbacholine and pentagastrin].
In chronic experiments on dogs with Basov 's stomach fistulas and pvc catheters implanted into the jugular vein the authors studied the effects of noradrenaline and adrenaline (30 mg/kg) on gastric secretion stimulated by pentagastrin. It was shown that the adrenagonists suppressed the pentagastrin-stimulated gastric secretion. The suppressing effect lasted 90 minutes after discontinuation of adrenaline or noradrenaline infusion.
D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000818:Animals; D002217:Carbachol / Q000494:pharmacology*; D002927:Cimetidine / Q000494:pharmacology; D004285:Dogs; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology*; D007545:Isoproterenol / Q000494:pharmacology; D010418:Pentagastrin / Q000494:pharmacology*; D011941:Receptors, Adrenergic / Q000187:drug effects; D011968:Receptors, Histamine / Q000187:drug effects
D000318:Adrenergic beta-Agonists; D011941:Receptors, Adrenergic; D011968:Receptors, Histamine; D002927:Cimetidine; D006632:Histamine; D002217:Carbachol; D010418:Pentagastrin; D007545:Isoproterenol
Mekhanizmy sekretsii zheludka u sobak pri infuzii gistamina, korbokholina i pentagastrina.