Effect of dose on increased etonitazene self-administration by rats due to food deprivation.
Rats were trained to self-administer IV-delivered etonitazene while food satiated. A wide range of etonitazene doses (5-80 micrograms/kg) and saline were tested under food satiation and food deprivation conditions. Food deprivation produced a parallel increase in the dose-response function under FR 1 and FR 16 schedule conditions.
D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005508:Food Deprivation / Q000502:physiology*; D007263:Infusions, Parenteral; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012646:Self Administration
D001562:Benzimidazoles