title: Benzodiazepines--misuse, abuse and dependency.
abstract: Recent European articles report many adverse effects of benzodiazepines, including aberrant symptoms, toxic states, dependency and withdrawal syndromes. The dependency may be primary high-dose, primary low-dose (therapeutic) or secondary dependency (multiple drug abuse). Withdrawal syndromes include rebound effects and benzodiazepine-specific reactions. Anxiolytic use of benzodiazepine should be limited to the treatment of short-term anxiety-producing situations.
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000188:drug therapy / Q000523:psychology; D001569:Benzodiazepines; D005260:Female; D006801:Humans; D013375:Substance Withdrawal Syndrome; D019966:Substance-Related Disorders / Q000523:psychology; D013997:Time Factors
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines