Developmental properties of the fast Na+ channel in embryonic cardiac cells using neurotoxins.
This paper describes how neurotoxins specific of the fast Na+ channel are used to study its differentiation in embryonic cardiac cells during heart ontogenesis. Structural and functional differentiation of the fast Na+ channel have been followed using both electrophysiological and biochemical techniques.
D000818:Animals; D001496:Batrachotoxins / Q000494:pharmacology; D002478:Cells, Cultured; D002642:Chick Embryo; D003064:Cnidarian Venoms / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects / Q000196:embryology*; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism*; D009498:Neurotoxins / Q000494:pharmacology*; D012615:Sea Anemones; D012964:Sodium / Q000378:metabolism*; D013779:Tetrodotoxin / Q000494:pharmacology*; D014701:Veratridine / Q000494:pharmacology
D001496:Batrachotoxins; D003064:Cnidarian Venoms; D007473:Ion Channels; D009498:Neurotoxins; D013779:Tetrodotoxin; D014701:Veratridine; D012964:Sodium