Junin virus infection of Calithrix jacchus: haematological findings.
Haematological changes produced by experimental Junin virus infection of a platyrrhine monkey, Callithrix jacchus were studied. Normocytic and normochromic anaemia appeared after 7 days post infection (p. i.), and increased steadily until day 21 p. i. Reticulocytes and circulating erythroblasts were elevated during the anaemia, reached a peak on day 7 p. i., and disappeared later. Platelets and leukocytes showed a significant decrease from days 14 and 18 p. i., respectively. These alterations could be attributed to the damage of bone marrow and lymphatic tissue.
D000818:Animals; D006477:Arenaviruses, New World; D001853:Bone Marrow / Q000473:pathology; D002144:Callithrix; D004906:Erythrocyte Count; D006478:Hemorrhagic Fever, American / Q000097:blood*; D007958:Leukocyte Count; D008297:Male; D008533:Megakaryocytes / Q000648:ultrastructure; D010976:Platelet Count; D012156:Reticulocytes