[Effect of cholinomimetics on L-glutamic acid release and uptake in the neostriatum of rats].
The effects of cholinomimetics on release and uptake of exogenic glutamic acid in the rat brain neostriatum in vivo and in vitro were studied. Carbocholine and nicotin were shown to inhibit the release, carbocholine acting directly on the presynaptic receptors whereas nicotin acting indirectly through the interneurons of neostriatum.
D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D002852:Chromatography, Ion Exchange; D003342:Corpus Striatum / Q000187:drug effects* / Q000378:metabolism; D005071:Evoked Potentials / Q000187:drug effects; D005971:Glutamates / Q000032:analysis / Q000378:metabolism*; D018698:Glutamic Acid; D066298:In Vitro Techniques; D008297:Male; D010277:Parasympathomimetics / Q000494:pharmacology*; D010477:Perfusion / Q000379:methods; D051381:Rats; D011919:Rats, Inbred Strains
D005971:Glutamates; D010277:Parasympathomimetics; D018698:Glutamic Acid; D000109:Acetylcholine
Vliianie kholinomimetikov na vysvobozdhenie i zakhvat L-glutaminovoĭ kisloty v neostriatume mozga krys.