Tofizopam selectively increases the affinity of benzo-diazepine binding sites for [3H]flunitrazepam but not for beta [3H] carboline-3-carboxylic acid ethyl ester.
D000818:Animals; D014151:Anti-Anxiety Agents / Q000378:metabolism* / Q000494:pharmacology*; D001569:Benzodiazepines / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism; D002243:Carbolines / Q000378:metabolism*; D002531:Cerebellum / Q000378:metabolism; D005260:Female; D005445:Flunitrazepam / Q000378:metabolism*; D007211:Indoles / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011956:Receptors, Cell Surface / Q000187:drug effects*; D011963:Receptors, GABA-A; D009435:Synaptic Transmission / Q000187:drug effects
D014151:Anti-Anxiety Agents; D002243:Carbolines; D007211:Indoles; D011956:Receptors, Cell Surface; D011963:Receptors, GABA-A; D001569:Benzodiazepines; D005445:Flunitrazepam; C024915:beta-carboline-3-carboxylic acid ethyl ester; C012582:tofisopam