Plasma insulin response and food intake in pseudopregnant rats.
1. Plasma insulin response to an intravenous glucose injection was measured in anaesthetised pseudopregnant and non-pregnant rats. Food intakes and body composition were also compared in pseudopregnant and non-pregnant animals. 2. The insulin responses and food intakes were greater in the pseudopregnant group. 3. Pseudopregnancy increased the fat-free dry weight of the animals and there was a tendency for the proportion of fat to be increased. 4. The results provide further evidence to indicate that in the rat progesterone plays a significant part in increasing insulin secretion during pregnancy.
D000818:Animals; D004435:Eating; D005260:Female; D005947:Glucose / Q000494:pharmacology; D007328:Insulin / Q000097:blood*; D011555:Pseudopregnancy / Q000097:blood* / Q000503:physiopathology; D051381:Rats; D011919:Rats, Inbred Strains
D007328:Insulin; D005947:Glucose