Rapid tranquilization: a comparative study of thiothixene and haloperidol.
In a double-blind comparative clinical study, both thiothixene and haloperidol were found to be effective agents for rapid tranquilization of manic and schizophrenic patients. While no statistically significant difference in any of the psychopathological areas which may create a psychiatric emergency was found, results of this study provide further substantiation of the notion that thiothixene has favorable effects on anergia .
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy*; D010054:Brief Psychiatric Rating Scale; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*; D013888:Thiothixene / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D013888:Thiothixene; D006220:Haloperidol