Effects of lifelong administration of beta-phenylisopropylhydrazine hydrochloride and thiocarbamylhydrazine in mice.
beta-Phenylisopropylhydrazine hydrochloride and thiocarbamylhydrazine were separately administered as 0.0312 and 0.0156% solutions in drinking water for life to randomly bred Swiss mice. The consumption of the chemicals resulted in no detectable tumorigenic effects in the treated animals, and it is therefore concluded that these compounds are apparently noncarcinogenic under the present experimental conditions.
D000818:Animals; D002273:Carcinogens; D005260:Female; D006834:Hydrazines / Q000633:toxicity*; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced; D012663:Semicarbazides / Q000633:toxicity*
D002273:Carcinogens; D006834:Hydrazines; D012663:Semicarbazides; C005151:thiosemicarbazide