Ultrastructure of juxtaglomerular cells correlated with biochemical parameters in a hibernator.
Ultrastructural features of juxtaglomerular cells have been correlated with plasma and kidney analyses from non-hibernating, hibernating and awakening ground squirrels. Juxtaglomerular cells in kidneys from hibernating animals show signs of increased activity. Plasma samples from hibernating animals show a significant increase in magnesium. Kidney analyses from hibernating animals, show glycogen increases and lactate and inorganic phosphate decrease significantly. Adenosine triphosphate remains the same. Maintenance of high-energy phosphates in the hibernating kidney is essential to maintaining sodium transport and osmotic pressure. This coupled with a functional renin-angiotensin system regulates water and electrolyte balance.
D000818:Animals; D001160:Arterioles / Q000648:ultrastructure; D004573:Electrolytes / Q000097:blood; D006605:Hibernation; D007606:Juxtaglomerular Apparatus / Q000166:cytology / Q000648:ultrastructure*; D007668:Kidney / Q000098:blood supply / Q000378:metabolism*; D009997:Osmotic Pressure; D012083:Renin / Q000097:blood; D012589:Sciuridae
D004573:Electrolytes; D012083:Renin