Electrical activity of mouse motor nerve terminals.
Focal extracellular recording was made from presynaptic motor nerve terminals made visible directly in in vitro preparations of mouse intercostalis intimi muscles. The demonstration of a net inward current distally in these terminals at sites of transmitter release allow the conclusion that the mammalian terminal is electrically excitable, contrary to a recent claim that it is not.
D000818:Animals; D007366:Intercostal Muscles / Q000294:innervation*; D007473:Ion Channels / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects; D051379:Mice; D009046:Motor Neurons / Q000502:physiology*; D009469:Neuromuscular Junction / Q000502:physiology*; D011188:Potassium / Q000378:metabolism; D011901:Ranvier's Nodes / Q000502:physiology; D012964:Sodium / Q000378:metabolism; D009435:Synaptic Transmission / Q000187:drug effects; D013779:Tetrodotoxin / Q000494:pharmacology
D007473:Ion Channels; D013779:Tetrodotoxin; D012964:Sodium; D011188:Potassium