title: Low forestomach acidity in the rat and the role of the gastric bolus.
abstract: pH measurements were recorded from the mucosal surfaces of the rat forestomach and glandular stomach following stimulation of acid-secretion by pentagastrin. Animals containing a normal gastric bolus showed lower forestomach acidity (pH 4.3, cf. 3.2) as did coprophagic animals that contained a fecal gastric bolus (pH 6.0, cf. 3.6). Animals without a gastric bolus showed higher forestomach acidity (pH 2.3, cf. 3.0). It is concluded that the presence of a food bolus is prerequisite to maintenance of lower forestomach acidity in rats.
mesh_terms: D000818:Animals; D003303:Coprophagia / Q000378:metabolism; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D051381:Rats / Q000378:metabolism*; D011919:Rats, Inbred Strains; D013217:Starvation / Q000378:metabolism; D013270:Stomach / Q000033:anatomy & histology; D014018:Tissue Distribution