Chlamydia trachomatis in term pregnancy. isolation and serological study with a case report.
The prevalence of cervical Chlamydia trachomatis infection in healthy, symptomless full-term pregnant women (n = 92) was found to be low (1.1%). Chlamydial cervical IgA antibodies, as measured by solid-phase radioimmunoassay (RIA), were found in 5.3%, but amniotic fluid chlamydial RIA IgA antibodies were almost absent. Serum IgG antibodies were measured with indirect immunofluorescence (IF). Of the mothers 9.8% had a titer greater than or equal to 1:64, correlating closely with the figure of 10.9% for infants' cord-blood IF serology. Finally, a case report is presented. A child born to a Chlamydia trachomatis positive mother developed isolation positive chlamydial pneumonia.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology; D011014:Pneumonia / Q000209:etiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011863:Radioimmunoassay
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A