title: [Drug-induced respiratory disorders].
abstract: Drugs induced respiratory disorders include bronchospasm, extrinsic alveolitis, and diffuse interstitial pulmonary fibrosis. Bronchospasm may be due to the action of pharmacodynamic agents on autonomic control of bronchial tone (beta-blockers, beta-agonists...) or to a hypersensitivity reaction (penicillins, sulfonamides, anti-inflammatory compounds...). Extrinsic alveolitis usually follows administration of anti-infective medication but other drugs may be implicated. Prolonged use of a wide variety of drugs, particularly cytotoxic agents, is necessary to provoke the onset of a diffuse interstitial pulmonary fibrosis.
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000009:adverse effects; D000318:Adrenergic beta-Agonists / Q000009:adverse effects; D000319:Adrenergic beta-Antagonists / Q000009:adverse effects; D000542:Alveolitis, Extrinsic Allergic / Q000209:etiology*; D000890:Anti-Infective Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D001249:Asthma / Q000139:chemically induced; D001986:Bronchial Spasm / Q000139:chemically induced*; D005730:Ganglionic Blockers / Q000009:adverse effects; D006801:Humans; D008784:Methysergide / Q000009:adverse effects; D009581:Nitrofurans / Q000009:adverse effects; D010100:Oxygen / Q000009:adverse effects; D010277:Parasympathomimetics / Q000009:adverse effects; D011217:Practolol / Q000009:adverse effects; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
chemical_list: D000316:Adrenergic alpha-Agonists; D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D005730:Ganglionic Blockers; D009581:Nitrofurans; D010277:Parasympathomimetics; D010100:Oxygen; D011217:Practolol; D008784:Methysergide
vernacular_title: Accidents respiratoires médicamenteux.