title: Drug-induced rapid cycling: possible outcomes and management.
abstract: Rapid cycling of mood change induced by antidepressant drugs has recently emerged as a significant diagnostic and therapeutic problem. The author describes two additional cases. Cessation of treatment with the offending drug may leave the patient depressed, manic, or euthymic or in a state of continued rapid cycling. The author suggests an approach to management of this condition.
mesh_terms: D000328:Adult; D000368:Aged; D000639:Amitriptyline / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000188:drug therapy / Q000523:psychology; D003984:Dibenzazepines / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D016651:Lithium Carbonate; D008297:Male
chemical_list: D003984:Dibenzazepines; D000639:Amitriptyline; D016651:Lithium Carbonate; D008094:Lithium