[Effect of thymectomy and polypeptide thymus factor on development of alimentary reflex in rats].
The effects of thymectomy and polypeptide thymus factor on the formation of alimentary instrumental reflex were studied in rat experiments. It was shown that 8-9 months after thymectomy the percentage of rats trained the alimentary instrumental reflex decreased from 85.7 +/- 9.7 (sham-operated animals) to 22.2 +/- 14.7 (thymectomized animals). By the same time T lymphocytes had been completely eliminated from the spleen. The motor activity and its pattern were similar in the sham-operated and thymectomized animals. Daily administration of the polypeptide thymus factor (thymarine) intramuscularly to the rats at a rate of 1 mg per animal for 10 days recovered the percentage of the trained animals to the control levels.
D000818:Animals; D000954:Antigens, Surface / Q000276:immunology; D003429:Cross Reactions; D005247:Feeding Behavior / Q000502:physiology*; D007958:Leukocyte Count; D008297:Male; D051381:Rats; D012018:Reflex / Q000502:physiology*; D013601:T-Lymphocytes / Q000276:immunology; D018800:Thy-1 Antigens; D013934:Thymectomy; D013951:Thymus Hormones / Q000276:immunology / Q000502:physiology*
D000954:Antigens, Surface; D018800:Thy-1 Antigens; D013951:Thymus Hormones; C017757:thymarin
Vliianie timéktomii i polipeptidnogo faktora timusa na vyrabotku pishchevogo instrumental'nogo refleksa u krys.