Outcome of fetal ventriculomegaly.
Ventriculomegaly was diagnosed in 50 fetuses in the perinatal ultrasound unit of Yale-New Haven Medical Center. The outcomes were elective abortion, 13 (26%); antepartum death, 0 (0%); intrapartum death, 7 (14%); neonatal death within 24 h, 11 (22%); neonatal death after 24 h and within 28 days, 3 (6%); death after 28 days, 2 (4%); survival, 14 (28%). 70% of the deaths were associated with severe congenital anomalies or intrapartum cephalocentesis. Of the 14 survivors, 6 (43%) had Bayley mental or Stanford-Binet scores of over 80, 2 (14%) had scores from 65 to 80, and 6 (43%) had scores of less than 65. The differences in outcome between this antenatal population and previously described neonatal populations with ventriculomegaly may result from the high rate (84%) of abnormalities in association with ventriculomegaly in this study and selection biases in neonatal studies.
D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000401:mortality; D000028:Abortion, Induced; D002552:Cerebral Ventricles / Q000196:embryology / Q000473:pathology; D002557:Cerebrospinal Fluid Shunts; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000401:mortality; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography