[Multiple endocrine neoplasia syndrome type I - familial occurrence].
Endocrine adenomatosis of Langerhan's islets (gastrinoma), parathyroid, pituitary gland and adrenals manifested itself at a proband by Zollinger-Ellison syndrome and perhaps hyperparathyroidism. Proband late brother's autopsy was reviewed and a similar morphology was found with Cushing's syndrome and peptic ulcer. Both brethren's mother died from a complication of recurring peptic ulcer.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004702:Endocrine Glands / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000235:genetics* / Q000473:pathology*
Syndrom mnohotné endokrinní neoplazie, typ I--rodinný výskyt.