[Prostaglandins F2alpha and E content and uptake of Ca2+ in the myometrium during different functional states].
It is shown that the amount of prostaglandins F2alpha and E in myometrium of female rabbits and a woman decreases in the process of pregnancy and increases during delivery as compared to the control. The 10(-6)M concentration of prostaglandin F2alpha evokes an intensive Ca2+ uptake by myometrium strips both in normal and in pregnant animals but has no effect on the Mg2+, Ca2+-ATPase activity of sarcolemma vesicles. The Ca2+ uptake by the myometrium strips is not affected by prostaglandin F2alpha in the presence of NaF and N-ethylmaleimide inhibiting the ATP-dependent transport of Ca2+.
D000818:Animals; D001693:Biological Transport, Active; D017301:Ca(2+) Mg(2+)-ATPase; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D015237:Dinoprost; D005033:Ethylmaleimide / Q000494:pharmacology; D005260:Female; D007700:Kinetics; D009215:Myometrium / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal; D011458:Prostaglandins E / Q000378:metabolism*; D011460:Prostaglandins F / Q000378:metabolism*; D011817:Rabbits; D012508:Sarcolemma / Q000201:enzymology; D012969:Sodium Fluoride / Q000494:pharmacology; D014599:Uterus / Q000378:metabolism*
D011458:Prostaglandins E; D011460:Prostaglandins F; D012969:Sodium Fluoride; D015237:Dinoprost; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D005033:Ethylmaleimide; D002118:Calcium
Soderzhanie prostaglandinov F2al'fa i E i pogloshchenie Ca2+ v miometrii pri razlichnykh funktsional'nykh sostoianiiakh.