[Effect of several neurohumors on the response of cells of the lateral geniculate nucleus of the rat, evoked by electric stimulation of the retina].
In anesthetized rats the retina is electrically stimulated. The evoked responses are recorded in the lateral geniculate cells with glass micro-pipettes filled with NaCl. Two patterns of discharges are elicited: non-alternating responses (NA) and alternating responses (A). The evoked responses are abolished when cobalt or aspartate is injected into the eye suggesting that the discharges are generated at the outer plexiform layer of the retina. Furthermore these data indicate that the electrical current does not activate directly the retinal ganglion cells. Glycine and G A B A had differential effects on the evoked responses. The results are compared with those obtained on rabbits.
D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology; D003035:Cobalt / Q000494:pharmacology; D004558:Electric Stimulation; D005829:Geniculate Bodies / Q000187:drug effects / Q000502:physiology*; D005998:Glycine / Q000494:pharmacology; D007700:Kinetics; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D010775:Photic Stimulation; D051381:Rats; D012160:Retina / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D018377:Neurotransmitter Agents; D001224:Aspartic Acid; D003035:Cobalt; D005680:gamma-Aminobutyric Acid; D005998:Glycine
Influence de quelques neuromédiateurs sur les réponses des cellules du corps genouillé latéral du rat, évoquées par la stimulation électrique de la rétine.