[Reaction of the endocrine apparatus of the stomach to thyroxine administration].
Histochemical and electron microscopy identification revealed five types of endocrine cells (A-like, ECL, G, D, EC) in the gastric fundal and pyloric mucosa. Quantitative positive correlation was found between the revealed ECL, G cells and HCl secretion after the 10-day L-thyroxin administration. The correlation became negative after a longer administration. The ultrastructural changes of A-like ECL and G-cells (L-thyroxin for 10 days) proved their increased functional activity. After a longer period of L-thyroxin administration the ultrastructural characteristics of EC, D-cells suggested their degranulation. The majority of A-like, ECL and G-cells existed in the storing phase due to blocking of the extrusion phase.
D000818:Animals; D002838:Chromaffin System / Q000378:metabolism*; D004759:Enterochromaffin Cells / Q000378:metabolism* / Q000648:ultrastructure; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D005755:Gastrins / Q000378:metabolism; D006636:Histamine Release; D006980:Hyperthyroidism / Q000503:physiopathology; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism; D013974:Thyroxine / Q000494:pharmacology* / Q000502:physiology
D005755:Gastrins; D012701:Serotonin; D013004:Somatostatin; D013974:Thyroxine
Reaktsiia éndokrinnogo apparata zheludka pri vvedenii v organizm tiroksina.