[Value of plasma exchange in necrotizing angeitis. 11 cases].
Plasma exchanges proved useful in a series of 11 patients with necrotizing angeitis resistant to conventional treatment (corticosteroids alone in 6 cases and combined with cyclophosphamide in 5 cases). Among the 9 patients alive after 18 months' follow-up, 5 were in remission without treatment. The only disturbing complication of plasma exchanges was hepatitis B in 3 of the 4 survivors who received frozen fresh plasma as substitute. It is suggested that these immuno-compromized patients should receive diluted albumin instead of fresh frozen plasma.
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D001167:Arteritis / Q000628:therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010951:Plasma Exchange / Q000009:adverse effects; D010488:Polyarteritis Nodosa / Q000628:therapy; D011241:Prednisone / Q000627:therapeutic use
D000936:Antigen-Antibody Complex; D003520:Cyclophosphamide; D011241:Prednisone
Intérêt des échanges plasmatiques au cours des angéites nécrosantes. 11 cas.