Three-ply walled w/o/w microcapsules formed by a multiple emulsion technique.
A new method of microencapsulation is described. Interfacial rheological studies had shown the formation of a rigid bipolymer film at the interface between an aqueous solution of a water-soluble polymer and a non-aqueous solution of an oil-soluble polymer. This led to the idea that small spherical bodies might be formed on making a w/o/w emulsion from these solutions. The present work has shown that ethyl cellulose/acacia microcapsules are formed when the organic solvent ethyl acetate is removed from the multiple emulsion drops. These microcapsules may be obtained as a free-flowing powder.
D002214:Capsules; D002482:Cellulose / Q000031:analogs & derivatives; D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D004655:Emulsions; D008854:Microscopy, Electron; D010316:Particle Size; D011208:Powders; D012995:Solubility; D013500:Surface Tension
D002214:Capsules; D004655:Emulsions; D011208:Powders; C013517:ethyl cellulose; D002482:Cellulose