title: Mosaicism 48,XX,+8,+21/47,XX,+21 in Down syndrome and rapid progression from preleukaemia to acute leukaemia.
mesh_terms: D000208:Acute Disease; D002904:Chromosomes, Human, 21-22 and Y / Q000648:ultrastructure; D002906:Chromosomes, Human, 6-12 and X / Q000648:ultrastructure; D004314:Down Syndrome / Q000150:complications / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000150:complications / Q000235:genetics* / Q000473:pathology; D009030:Mosaicism; D011289:Preleukemia / Q000235:genetics* / Q000473:pathology; D014314:Trisomy