[Correlation between the changes in the functional state of enzyme and hormonal systems of the mature rat].
Content of progesterone and cortisol was studied in blood plasma. Activities of organelle-specific enzymes were estimated in mitochondria (malate dehydrogenase, glutamate dehydrogenase, H + ATPase) and in endoplasmic reticulum (inosine-5-diphosphatase) of liver, kidney tissues and blood serum of rats, which were born after the influence of embryotoxic effectors. Correlation was found in alterations of the patterns studied. The steroid hormonal systems appear to affect the stability of mitochondrial and microsomal membranes in liver and kidney tissues of experimental animals.
D017766:Acid Anhydride Hydrolases; D000818:Animals; D004622:Embryo, Mammalian / Q000187:drug effects; D004721:Endoplasmic Reticulum / Q000201:enzymology*; D005260:Female; D005557:Formaldehyde / Q000633:toxicity; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D006854:Hydrocortisone / Q000097:blood*; D007668:Kidney / Q000201:enzymology*; D008291:Malate Dehydrogenase / Q000378:metabolism; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011374:Progesterone / Q000097:blood*; D006180:Proton-Translocating ATPases / Q000378:metabolism; D051381:Rats
D005557:Formaldehyde; D011374:Progesterone; D008291:Malate Dehydrogenase; D005969:Glutamate Dehydrogenase; D010744:Phosphoric Monoester Hydrolases; D017766:Acid Anhydride Hydrolases; C021446:inosine diphosphatase; D006180:Proton-Translocating ATPases; D006854:Hydrocortisone
Issledovanie korreliatsionnoĭ vzaimosviazi mezhdu izmeneniiami funktsional'nogo sostoianiia nekotorykh fermentnykh i gormonal'nykh sistem u polovozrelykh krys.