Milenperone. A selective drug for the control of behavioral disorders in epileptic and alcoholic patients.
Thirty-four patients took part in an 8-week open investigation aimed at evaluating the efficacy of low oral doses of milenperone as non-sedative neuroleptic drug in the management of aggressive behavior in alcoholics and epileptics. Significant improvements were recorded for respectively 11 and 13 out of 16 evaluable symptoms in alcoholics and epileptics. The symptoms tyrannical and rebellious behavior, aggressive speech and actions, impulsivity, egotism, irritability, use of bad language and bad temper improved in both groups of patients. Out and inpatients, the latter being on milenperone as either adjuvant or monotherapy, responded comparably well. No important side-effects were reported.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000374:Aggression / Q000187:drug effects*; D000437:Alcoholism / Q000188:drug therapy*; D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged
D014150:Antipsychotic Agents; D001562:Benzimidazoles; C041586:milenperone