Treatment of psoriasis with somatostatin.
In 22 of 26 patients suffering from psoriasis the drip infusion therapy with Somatostatin, an inhibitor of the human growth hormone (HGH), leads to complete or partial remission of skin lesions. Fast reduction of joint pains in arthropathic psoriasis could be observed in four of four patients. The repeated measurement of HGH blood level showed a decrease of HGH in five cases following the Somatostatin therapy combined with the clinical remission.
D000328:Adult; D000368:Aged; D005260:Female; D013006:Growth Hormone / Q000037:antagonists & inhibitors / Q000097:blood; D006728:Hormones / Q000008:administration & dosage; D006801:Humans; D007263:Infusions, Parenteral; D007592:Joint Diseases / Q000097:blood / Q000188:drug therapy*; D008875:Middle Aged; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*; D012075:Remission, Spontaneous; D013004:Somatostatin / Q000008:administration & dosage*
D006728:Hormones; D013004:Somatostatin; D013006:Growth Hormone