Interferon-inducing activity of Salmonella minnesota re glycolipid--anti-glycolipid immune complexes.
Immune complexes formed from Salmonella minnesota Re glycolipid (Gl) and its derivative DMSO-Gl with homologous antibodies exhibited stronger interferon (IFN)-inducing activity than the free Gl (4- to 32-fold increase and 8- to 64-fold increase respectively). This effect was found dose-dependent.
D000818:Animals; D000907:Antibodies, Bacterial; D000936:Antigen-Antibody Complex / Q000502:physiology*; D000942:Antigens, Bacterial; D004121:Dimethyl Sulfoxide; D006017:Glycolipids / Q000276:immunology* / Q000494:pharmacology; D007370:Interferon Type I / Q000096:biosynthesis*; D007962:Leukocytes / Q000378:metabolism*; D051379:Mice; D012475:Salmonella / Q000276:immunology*
D000907:Antibodies, Bacterial; D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D006017:Glycolipids; D007370:Interferon Type I; D004121:Dimethyl Sulfoxide