title: Premenstrual syndrome.
abstract: Symptoms related to the premenstrual syndrome (PMS) are experienced by a large segment of the susceptible population. Its nature and the extent to which it is a problem are not well delineated and are subjects of significant controversy. Its etiology is uncertain. Cortical centers and neurotransmitters appear to play an important role. Its influence on the expression of other diseases and their influence on its presence or its severity have received insufficient study. Various approaches to therapy are commonly used, including birth control pills, diuretics, minor tranquilizers, and bromocriptine, but no single drug therapy is consistently effective. A strong placebo effect has been demonstrated with all medications that have been used.
mesh_terms: D000293:Adolescent; D000328:Adult; D001519:Behavior / Q000502:physiology; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D008598:Menstruation; D018377:Neurotransmitter Agents / Q000502:physiology; D011293:Premenstrual Syndrome / Q000175:diagnosis / Q000628:therapy; D011597:Psychomotor Performance / Q000502:physiology
chemical_list: D018377:Neurotransmitter Agents