Deferoxamine treatment of acute iron intoxication in pregnancy.
Acute iron intoxication in pregnancy presents a dilemma to the clinician. Toxic levels of iron are associated with severe complications and can be fatal, but the effective iron chelator, deferoxamine, has possible teratogenic potential. The present report discusses the clinical indications that can support the administration of deferoxamine for iron intoxication in pregnancy and discusses the benefits and risks of its usage.
D000028:Abortion, Induced; D000293:Adolescent; D003676:Deferoxamine / Q000627:therapeutic use*; D005260:Female; D005290:Ferric Compounds / Q000506:poisoning; D006801:Humans; D007486:Ipecac / Q000627:therapeutic use; D007501:Iron / Q000097:blood / Q000506:poisoning*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011253:Pregnancy in Adolescence; D011275:Pregnancy, Unwanted; D013723:Teratogens / Q000627:therapeutic use*
D005290:Ferric Compounds; D013723:Teratogens; C024823:ferric sulfate; D007486:Ipecac; D007501:Iron; D003676:Deferoxamine