title: [Intracranial complications in sinusitis].
abstract: Between 1931 und 1981 a total of 60 patients with endocranial complications of paranasal sinus infections was observed at the ENT clinic of the University Hospital in Zurich. The symptomatology, clinical findings, incidence and eventual course of the different endocranial complications are discussed in relation to treatment before and after the availability of antibiotics. A dramatic decrease in incidence of endocranial complications occurred following the advent of antibiotic use and early surgical drainage of the involved cavities. The mortality rate between 1931 an 1945 was 86%, between 1945 and 1949 40% and between 1950 and 1981 5%.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D013354:Empyema, Subdural / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D012852:Sinusitis / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Endokranielle Komplikationen bei Sinusitis.