Chemical modification in situ of Escherichia coli 50 S ribosomal proteins by the site-specific reagent pyridoxal phosphate. Inactivation of the elongation factor-G-dependent GTPase and of the association with the small ribosomal subunit.
D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D020963:GTP Phosphohydrolase-Linked Elongation Factors / Q000378:metabolism*; D007700:Kinetics; D008970:Molecular Weight; D020653:Peptide Elongation Factor G; D010445:Peptide Elongation Factors / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D011732:Pyridoxal Phosphate / Q000494:pharmacology*; D012269:Ribosomal Proteins / Q000302:isolation & purification / Q000378:metabolism*; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism*
D020653:Peptide Elongation Factor G; D010445:Peptide Elongation Factors; D012269:Ribosomal Proteins; D011732:Pyridoxal Phosphate; D010744:Phosphoric Monoester Hydrolases; D020963:GTP Phosphohydrolase-Linked Elongation Factors