Effects of adrenalectomy on energy balance, diet-induced thermogenesis and brown adipose tissue in adult cafeteria-fed rats.
Feeding adult male rats a palatable cafeteria diet stimulated energy intake and expenditure but also raised body weight and energy gains. Bilateral adrenalectomy (ADX) had little effect on stock-fed animals, but prevented the development of obesity in cafeteria-fed rats by depressing food intake and energetic efficiency. Adrenalectomy also markedly increased the thermogenic activity of brown adipose tissue, and depressed insulin levels, particularly in the cafeteria group.
D002001:Adipose Tissue, Brown / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D001833:Body Temperature Regulation; D001835:Body Weight; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004734:Energy Metabolism; D005502:Food; D007328:Insulin / Q000097:blood; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D004040:Dietary Carbohydrates; D007328:Insulin