Academic stress, power motivation, and decrease in secretion rate of salivary secretory immunoglobulin A.
The effect of academic stress on immune function, as measured by the rate of secretion of salivary secretory immunoglobulin A (s-IgA), was studied prospectively in 64 first-year dental school students. Perceived stress and s-IgA secretion rate were measured five times--during an initial low-stress period, three high-stress periods coinciding with major examinations, and a final low-stress period. The s-IgA secretion rate was significantly lower in high-stress than low-stress periods for the whole group. In addition, personality characteristics differentiated patterns of s-IgA secretion rates. Students characterised by a great need to establish and maintain warm personal relationships secreted more s-IgA at each point than did all other subjects. The s-IgA secretion rates of those with a high inhibited need for power continued to decline through the final low-stress period rather than recovering as in all other subjects.
D000328:Adult; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D008297:Male; D009042:Motivation; D010551:Personality; D012463:Saliva / Q000276:immunology*; D013315:Stress, Psychological / Q000209:etiology / Q000276:immunology*; D013335:Students, Dental / Q000523:psychology*
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory