title: Effects of cold acclimation on the feeding pattern and energetic metabolism of genetically obese Zucker rats.
abstract: 1. The feeding pattern, growth rate and energetic metabolism were studied in obese Zucker rats of 5-12 weeks of age kept at ambient temperatures of 22 or 10 degrees C. 2. During this period, the increment in obesity of the 22 degrees C-exposed animal was found to be due to diurnal hyperphagia and not to a lowered resting metabolism. 3. In the 10 degrees C-exposed rat the development of non-shivering thermogenesis associated with a lack of enhancement of food intake leads to prevent the obesity.
mesh_terms: D000064:Acclimatization; D000818:Animals; D001835:Body Weight; D003080:Cold Temperature; D004734:Energy Metabolism / Q000187:drug effects; D005247:Feeding Behavior / Q000502:physiology*; D005502:Food; D009638:Norepinephrine / Q000494:pharmacology; D009765:Obesity / Q000378:metabolism*; D010101:Oxygen Consumption; D051381:Rats; D011922:Rats, Mutant Strains / Q000378:metabolism*; D011924:Rats, Zucker / Q000378:metabolism*
chemical_list: D009638:Norepinephrine