Angiogenesis factor from human myocardial infarcts.
5 of 8 infarcted human myocardial tissues were shown to contain an angiogenesis factor which resembles that obtained from solid tumours. The concentration of angiogenesis factor, measured by radioimmunoassay, was similar to that in tumours. It is suggested that the myocardial-infarct angiogenesis factor modulates collateral enlargement or ingrowth of new blood vessels in the infarcted tissues.
D000368:Aged; D043925:Angiogenesis Inducing Agents / Q000378:metabolism*; D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology; D002196:Capillaries / Q000254:growth & development; D003429:Cross Reactions; D004285:Dogs; D006133:Growth Substances / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D008954:Models, Biological; D009203:Myocardial Infarction / Q000378:metabolism*; D009206:Myocardium / Q000276:immunology / Q000378:metabolism*; D009369:Neoplasms / Q000098:blood supply / Q000378:metabolism; D011863:Radioimmunoassay; D051381:Rats
D043925:Angiogenesis Inducing Agents; D000951:Antigens, Neoplasm; D006133:Growth Substances