title: Immunocytochemical identification of CRF-like and SRIF-like peptides in the brain and the pituitary of cyprinid fish.
abstract: Single and double immunocytochemical techniques were applied to the brain and pituitary of carps and goldfish. With the use of antiserum raised against synthetic corticotropin-releasing factor (CRF), immunoreactive perikarya were observed in the nucleus praeopticus and the nucleus praeopticus periventricularis. CRF-like-immunoreactive hypothalamic nerve fibers reach the pituitary. In cyprinids, some fine fibers enter the rostral neurohypophysis bordered by prolactin- and ACTH cells. Other thicker fibers extend ventrocaudally into the neurointermediate lobe. This CRF-like system appears to differ from the SRIF-like system, which is restricted to the proximal pars distalis of the pituitary containing somatotrophs.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D003346:Corticotropin-Releasing Hormone / Q000276:immunology / Q000378:metabolism*; D003530:Cyprinidae / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D010902:Pituitary Gland / Q000378:metabolism*; D013004:Somatostatin / Q000276:immunology / Q000378:metabolism*
chemical_list: D013004:Somatostatin; D003346:Corticotropin-Releasing Hormone