Homeostatic responses to water deprivation or hemorrhage in lactating and non-lactating Bedouin goats.
Three lactating and three non-lactating black Bedouin goats were subjected to four days of water deprivation or to hemorrhage. Four days of water deprivation caused body wt losses of 32 and 23% and plasma volume losses of 30 and 34% in lactating and non-lactating goats respectively. Plasma osmolality increased 17 and 15% in lactating and non-lactating goats. Plasma arginine vasopressin concentration rose from about 5 pg/ml to a mean of 36 pg/ml. Plasma renin activity increased from about 0.7 ng/ml/hr to a mean of 3.45 ng/ml/hr in lactating and to 3.15 ng/ml/hr in non-lactating goats. At 4.5 hr post-rehydration plasma osmolality and plasma vasopressin concentration were back to normal in non-lactating, but still elevated in lactating goats. Plasma renin activity increased after rehydration. Rapid blood volume loss of 21-28% increased plasma vasopressin concentration to 16-35 pg/ml in non-lactating and to 70 or greater than 500 pg/ml in lactating goats. It is concluded that black Bedouin goats are well adapted to endure severe dehydration and rapid rehydration, but that they (especially lactating animals) react strongly to rapid volume depletion.
D000818:Animals; D001127:Arginine Vasopressin / Q000097:blood; D005260:Female; D005440:Fluid Therapy; D006041:Goats / Q000502:physiology*; D006470:Hemorrhage / Q000097:blood / Q000503:physiopathology*; D006706:Homeostasis; D007774:Lactation; D011247:Pregnancy; D012083:Renin / Q000097:blood; D014868:Water Deprivation
D001127:Arginine Vasopressin; D012083:Renin