The effect of antihistamines on ultraviolet-light-induced erythema.
Because of the possible role of histamine as an early mediator of ultraviolet light induced erythema, we studied a group of volunteers treated with both H1 and H2 blockers, alone and in combination, before and at various time intervals after, UVL irradiation. No difference was found in the degree of erythema produced by any of the antihistamines used, whether alone or in combination, when compared with the saline control.
D004890:Erythema / Q000188:drug therapy* / Q000209:etiology; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D014466:Ultraviolet Rays / Q000009:adverse effects*
D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists