title: Immunochemical evidence for met-enkephalin-like and leu-enkephalin-like peptides in tissues of the earthworm, Lumbricus terrestris.
abstract: The presence of met- and leu-enkephalin-like immunoreactive materials in nerve, gut, seminal vesicle and body wall tissues of the earthworm Lumbricus terrestris has been demonstrated by means of radioimmunoassay technique. The greatest activity of met- and leu-enkephalin-like immunoreactivity in earthworm gut appears in regions of high digestive enzyme activity and gastrin-like immunoreactivity where it presumably plays a role in regulation of gut function. In all tissues studied the levels of met-enkephalin-like immunoreactivity were higher than that of leu-enkephalin-like immunoreactivity. Dual localization of met- and leu-enkephalin-like immunoreactivity in earthworm gut and nerve tissues follows the pattern observed of peptide hormones in vertebrates which are common to both endocrine and non-endocrine tissues.
mesh_terms: D000818:Animals; D004743:Enkephalin, Leucine / Q000378:metabolism*; D004744:Enkephalin, Methionine / Q000378:metabolism*; D008297:Male; D009835:Oligochaeta / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D010455:Peptides; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine