title: Studies of pyrimidine metabolism during chick development: enzymes involved in CMP breakdown.
abstract: The pattern of cytidylate phosphatase, cytidine and cytosine deaminase has been studied in brain, liver, heart and thigh muscles during chick development. The enzymes involved in CMP catabolism appear in the tissues examined at different developmental periods. In the brain and heart a "salvage pathway" would appear in the pyrimidine metabolism earlier than in the purine one. An attempt has been made to explain the probable physiological role, in relation to differentiation, of the metabolic pathways observed in the tissues examined.
mesh_terms: D015720:5'-Nucleotidase; D000818:Animals; D001921:Brain / Q000201:enzymology; D002642:Chick Embryo; D002645:Chickens / Q000254:growth & development / Q000378:metabolism*; D003564:Cytidine Deaminase / Q000378:metabolism; D003568:Cytidine Monophosphate / Q000378:metabolism*; D043525:Cytosine Deaminase; D003597:Cytosine Nucleotides / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D009132:Muscles / Q000378:metabolism; D009700:Nucleoside Deaminases / Q000378:metabolism; D009708:Nucleotidases / Q000378:metabolism; D011743:Pyrimidines / Q000378:metabolism*
chemical_list: D003597:Cytosine Nucleotides; D011743:Pyrimidines; D009708:Nucleotidases; D015720:5'-Nucleotidase; D009700:Nucleoside Deaminases; D043525:Cytosine Deaminase; D003564:Cytidine Deaminase; D003568:Cytidine Monophosphate