Immunity and rickettsial infection: a review.
Immunity to rickettsiae is enhanced by both T-lymphocytes and humoral antibodies; however, the principal effector of rickettsial killing is the macrophage. Lymphokines may play an important role. There is undoubtedly a complex in vivo interaction between the immune, phagocytic, and inflammatory host defenses against these obligate intracellular bacteria.
D000917:Antibody Formation; D006801:Humans; D007111:Immunity, Cellular; D008222:Lymphokines / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D012281:Rickettsia / Q000276:immunology; D012282:Rickettsia Infections / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D014612:Vaccines / Q000276:immunology
D008222:Lymphokines; D014612:Vaccines