title: Arginine vasotocin alters hamster pituitary LH and prolactin secretion in vitro.
abstract: 1. Arginine vasotocin (AVT) stimulated the release of both luteinizing hormone (LH) and prolactin (PRL) from normal hamster (Mesocricetus auratus) anterior pituitary glands in a dose-dependent manner. 2. AVT significantly augmented the depressed level of PRL release from pituitaries of blind-pinealectomized animals. 3. LH release from the pituitaries of blinded hamsters was inhibited by AVT while FSH levels were unaffected.
mesh_terms: D000818:Animals; D001766:Blindness / Q000503:physiopathology; D006224:Cricetinae; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D008647:Mesocricetus; D010870:Pineal Gland / Q000502:physiology; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism*; D014668:Vasotocin / Q000494:pharmacology*
chemical_list: D011388:Prolactin; D007986:Luteinizing Hormone; D014668:Vasotocin