title: (-)-alpha-Acetylmethadol for treatment of chronic pain patients who abuse opioids.
abstract: (-)-alpha-Acetylmethadol (LAAM) is an opioid with a duration of action up to 72 h. It appeared to relieve pain and eliminate abuse of opioids in three of four patients who had chronic pain secondary to permanent, anatomical alterations. LAAM may be very helpful in the treatment of many chronic pain patients.
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008691:Methadone / Q000031:analogs & derivatives*; D008692:Methadyl Acetate / Q000627:therapeutic use*; D008875:Middle Aged; D009293:Opioid-Related Disorders; D010146:Pain / Q000188:drug therapy*
chemical_list: D000701:Analgesics, Opioid; D008692:Methadyl Acetate; D008691:Methadone