Case report of phenothiazine-induced torsade de pointes.
A patient with schizophrenia developed torsade de pointes, a life-threatening cardiac arrhythmia, due to administration of phenothiazines. An intravenous infusion of isoproterenol improved the symptoms. The etiology and treatment of the syndrome are discussed.
D014150:Antipsychotic Agents / Q000009:adverse effects*; D006801:Humans; D007263:Infusions, Parenteral; D007545:Isoproterenol / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines; D012559:Schizophrenia / Q000188:drug therapy*; D013610:Tachycardia / Q000139:chemically induced* / Q000188:drug therapy
D014150:Antipsychotic Agents; D010640:Phenothiazines; D007545:Isoproterenol