title: Carbon dioxide response curves following midazolam and diazepam.
abstract: The ventilatory response to carbon dioxide was measured in volunteers before, and at intervals after the i.v. administration of midazolam 0.075 mg kg-1 and diazepam 0.15 mg kg-1. In the doses used neither drug caused any statistically significant respiratory depression and there were no differences between the drugs.
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001569:Benzodiazepines / Q000494:pharmacology*; D002245:Carbon Dioxide; D003864:Depression, Chemical; D003975:Diazepam / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008874:Midazolam; D012119:Respiration / Q000187:drug effects*; D013997:Time Factors
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D002245:Carbon Dioxide; D003975:Diazepam; D008874:Midazolam