Enterotoxigenic Clostridium perfringens: a possible cause of antibiotic-associated diarrhoea.
Free Clostridium perfringens enterotoxin was detected in the stools of 11 patients with diarrhoea. All had high faecal counts of enterotoxigenic strains of C perfringens, mostly of serotypes not commonly associated with food poisoning. 10 of these 11 patients had severe or prolonged diarrhoea which had developed after antibiotic treatment. Enterotoxigenic C perfringens appears to be one of the causes of antibiotic-associated diarrhoea.
D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003015:Clostridium Infections / Q000209:etiology*; D003016:Clostridium perfringens / Q000378:metabolism; D003967:Diarrhea / Q000209:etiology* / Q000382:microbiology; D004768:Enterotoxins / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000032:analysis / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D004768:Enterotoxins