Detection of human papillomavirus type 5 DNA in skin cancers of an immunosuppressed renal allograft recipient.
A renal allograft recipient with an epidermodysplasia-verruciformis-like syndrome was found to have human papillomavirus type 5 (HPV-5) in his benign warty lesions and HPV-5 DNA in two of his skin cancers. This finding points to a role for HPV-5 in skin oncogenesis in renal allograft recipients.
D000328:Adult; D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000382:microbiology*; D004279:DNA, Viral / Q000302:isolation & purification*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification; D012878:Skin Neoplasms / Q000209:etiology / Q000382:microbiology*; D013472:Sunlight / Q000009:adverse effects; D014412:Tumor Virus Infections
D000956:Antigens, Viral; D004279:DNA, Viral