Pulmonary infiltrates with eosinophilia due to glafenine.
Pulmonary hypersensitivity in a 36-year-old man manifested by fever, abnormal lung auscultation, lung infiltrates and blood eosinophilia had to be ascribed to glafenine, a widely used analgesic drug. The observation was confirmed by reappearance of symptoms and biochemical abnormalities on rechallenge with glafenine.
D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D005897:Glafenine / Q000009:adverse effects*; D006261:Headache / Q000188:drug therapy; D006801:Humans; D008297:Male; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D012130:Respiratory Hypersensitivity / Q000139:chemically induced / Q000150:complications; D062367:ortho-Aminobenzoates / Q000009:adverse effects*
D062367:ortho-Aminobenzoates; D005897:Glafenine; D000667:Ampicillin