title: Effect of embryonic age on aggregability, histogenesis and biochemical differentiation in the embryonic chick and quail neural retina.
abstract: In this paper, the different ages of the chicken and quail embryonic retina cell aggregates are used to examine the aggregation, histogenesis, and the induction of glutamine synthetase (GS) elicited by hydrocortisone. The results show that the GS inducibility in the retina cells increases at a slow rate, then rises sharply on the 9th day, and after 9 days, the GS inducibility of aggregates decreases with the increase of embryonic age. The observed value of induced GS activity in the chick retina cells coaggregate with quail embryonic retina cells is less than the expected value. Bispecific cell coaggregates were observed when the 9-day chicken embryonic retina cells and the 71/2-day quail embryonic retina cells were combined and coaggregated, the chicken and quail cells formed three retinal rosettes. When the 9-day chicken embryonic retina cells were commingled with the 13-day quail embryonic retina cells, in the coaggregates, only one retinal rosette was formed.
mesh_terms: D000818:Animals; D002449:Cell Aggregation; D002454:Cell Differentiation; D002642:Chick Embryo; D003370:Coturnix; D005974:Glutamate-Ammonia Ligase / Q000096:biosynthesis; D006854:Hydrocortisone / Q000494:pharmacology; D012160:Retina / Q000166:cytology / Q000196:embryology* / Q000201:enzymology
chemical_list: D005974:Glutamate-Ammonia Ligase; D006854:Hydrocortisone