title: Application of a Phaseolus vulgaris erythroagglutinating lectin agarose column for the specific detection of human hepatoma gamma-glutamyl transpeptidase in serum.
abstract: By making use of the structural change of the sugar chains of liver gamma-glutamyl transpeptidase associated with malignant transformation, a new method has been developed to distinguish human serum gamma-glutamyl transpeptidase associated with primary hepatoma from that of non-hepatoma patients. In principle, the method consists of affinity chromatography of the desialylated serum enzyme on a Phaseolus vulgaris erythroagglutinating lectin agarose column.
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D002847:Chromatography, Agarose; D006801:Humans; D008113:Liver Neoplasms / Q000201:enzymology*; D010835:Phytohemagglutinins; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D010835:Phytohemagglutinins; D005723:gamma-Glutamyltransferase