Calcium channel blocking drugs for chronic, stable angina. Verapamil.
Verapamil is effective primary therapy for angina pectoris at a dosage of about 120 mg three times a day. In equal doses it has the same antianginal effect as propranolol although the mechanism of action is different. Long-term therapy is effective and well tolerated. Side effects are few and if required, verapamil may be given with nitrates or beta-blockers.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000787:Angina Pectoris / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006207:Half-Life; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009566:Nitrates / Q000627:therapeutic use; D014700:Verapamil / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D009566:Nitrates; D014700:Verapamil