title: Analysis of binding surfaces: a methodology appropriate for the investigation of complex receptor mechanisms and multiple neurotransmitter receptors.
abstract: In this study we describe a novel experimental design: analysis of three-dimensional binding surfaces. Evidence is presented that a binding surface provides greater information content than does a single binding isotherm. This approach to the design and analysis of ligand binding studies should facilitate quantitative studies of the opiate receptor.
mesh_terms: D000818:Animals; D007700:Kinetics; D008433:Mathematics; D008959:Models, Neurological; D018377:Neurotransmitter Agents / Q000378:metabolism*; D011485:Protein Binding; D017981:Receptors, Neurotransmitter / Q000378:metabolism*
chemical_list: D018377:Neurotransmitter Agents; D017981:Receptors, Neurotransmitter