An unusual cause of attacks of focal cerebral symptoms: multiple endocrine neoplasia type IIA.
A case of MEN type IIa is described showing among other symptoms, three attacks of transient neurological symptoms. These were attributed to a localized, transient cerebral ischemia. The latter probably developed as a consequence of the concomitant occurrence of different phenomena: the existence of hypercalcemia and on the other hand the secretion of vasoactive substances by one of the three tumours forming the MEN type IIa syndrome. The pheochromocytoma played an essential role because the symptoms did not recur after the bilateral adrenalectomy.
D000236:Adenoma / Q000150:complications; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D001037:Aphasia / Q000209:etiology; D002277:Carcinoma / Q000150:complications; D005260:Female; D006801:Humans; D006987:Hypesthesia / Q000209:etiology; D009377:Multiple Endocrine Neoplasia / Q000150:complications* / Q000175:diagnosis; D009422:Nervous System Diseases / Q000209:etiology*; D010243:Paralysis / Q000209:etiology; D010282:Parathyroid Neoplasms / Q000150:complications; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis; D013610:Tachycardia / Q000209:etiology; D013964:Thyroid Neoplasms / Q000150:complications