Aminergic neurotransmitters and adenylate cyclase in hydra.
Serotonin, dopamine and, in lesser amounts, norepinephrine were detected in Chlorohydra viridissima with electrochemical detection coupled to liquid chromatography (LCED). Treatment with reserpine induces a significant decrease in amine levels. Adenylate cyclase was found in Hydra tissue; the enzyme is stimulated by Mg, Mn and F and sensitive to guanine nucleotide activation. Dopamine, serotonin, GSH and glutamate do not affect cyclase activity.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001679:Biogenic Amines / Q000502:physiology*; D002395:Catecholamines / Q000378:metabolism; D000242:Cyclic AMP / Q000502:physiology; D004298:Dopamine / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D006165:Guanylyl Imidodiphosphate / Q000494:pharmacology; D006829:Hydra / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology*; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism
D001679:Biogenic Amines; D002395:Catecholamines; D018377:Neurotransmitter Agents; D012701:Serotonin; D006165:Guanylyl Imidodiphosphate; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D005978:Glutathione; D004298:Dopamine; D009638:Norepinephrine