Pharmacokinetics of alprazolam.
The metabolic profile and human pharmacokinetics of alprazolam, a benzodiazepine of unique chemical structure, are discussed. Alprazolam's pharmacokinetics may be altered by age and sex, body weight, and concurrent treatment with cimetidine. The unique structure of alprazolam may be associated with a wider range of biologic activity than is seen with other benzodiazepines.
D000367:Age Factors; D000525:Alprazolam; D014151:Anti-Anxiety Agents / Q000378:metabolism*; D001569:Benzodiazepines / Q000378:metabolism*; D001711:Biotransformation / Q000187:drug effects; D001835:Body Weight; D002927:Cimetidine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D012737:Sex Factors
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D002927:Cimetidine; D000525:Alprazolam