title: Genetic aspects of multiple endocrine neoplasia.
abstract: There are three well-delineated multiple endocrine neoplasia syndromes, all of which are inherited as autosomal dominant traits. Available evidence suggests that still more such entities exist. Despite intensive study, the nature of the genetic defect that results in these syndromes remains obscure.
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000235:genetics / Q000378:metabolism / Q000601:surgery; D002277:Carcinoma / Q000235:genetics / Q000378:metabolism / Q000601:surgery; D002454:Cell Differentiation; D005799:Genes, Dominant; D006729:Hormones, Ectopic / Q000378:metabolism; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000209:etiology / Q000235:genetics*; D009432:Neural Crest / Q000166:cytology; D010673:Pheochromocytoma / Q000235:genetics / Q000378:metabolism / Q000601:surgery; D013577:Syndrome; D013964:Thyroid Neoplasms / Q000235:genetics / Q000378:metabolism / Q000601:surgery; D015043:Zollinger-Ellison Syndrome / Q000235:genetics / Q000378:metabolism / Q000601:surgery
chemical_list: D006729:Hormones, Ectopic