title: Adrenergic regulation of fat-cell lipolysis in multiple symmetric lipomatosis.
abstract: The responsiveness towards catecholamines of normal and lipomatous fat cells of two male subjects suffering from multiple symmetric lipomatosis has been studied by means of a newly developed bioluminescent method for microdetermination of glycerol. In contrast to previous findings, lipomatous fat cells displayed normal alpha 2-and beta-adrenergic responsiveness in both subjects studied. The apparent discrepancies between the results of the present study and those reported by others therefore support the contention that multiple symmetric lipomatosis is a symptom with various underlying causes rather than a nosological entity.
mesh_terms: D000273:Adipose Tissue / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000494:pharmacology; D005990:Glycerol / Q000378:metabolism; D006801:Humans; D006984:Hypertrophy / Q000378:metabolism; D007545:Isoproterenol / Q000494:pharmacology; D008066:Lipolysis; D008068:Lipomatosis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
chemical_list: D000316:Adrenergic alpha-Agonists; D000318:Adrenergic beta-Agonists; D007545:Isoproterenol; D005990:Glycerol; D004837:Epinephrine