The use of nifedipine as third line therapy in the treatment of severe hypertension.
Twenty patients with essential hypertension difficult to control on a combination of beta blocker, diuretic and vasodilator (mainly hydralazine) drugs were subject to an open study. Replacement of the vasodilator by nifedipine appeared to produce a satisfactory antihypertensive response and a reduction in side effects.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D004232:Diuretics; D011725:Pyridines; D009543:Nifedipine