[Effect of oxmetidine and ranitidine on reflux behavior in patients with esophagitis].
The behavior of reflux under oxmetidine and ranitidine has been examined by long-term-pH-metry in patients with endoscopic proved oesophagitis and pathological, gastro-oesophageal reflux (GER). Both H2-receptor antagonists lead to a significant decrease of the GER over the entire period of measurement of 18 hours. Statistical significant differences comparing both substances could not be found, so that as well oxmetidine as ranitidine seem to be appropriate for the therapy of reflux diseases.
D004942:Esophagitis, Peptic / Q000188:drug therapy*; D005260:Female; D005745:Gastric Acidity Determination; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011899:Ranitidine / Q000627:therapeutic use*
D006635:Histamine H2 Antagonists; D007093:Imidazoles; D011899:Ranitidine; C027703:oxmetidine
Einfluss von Oxmetidin und Ranitidin auf das Refluxverhalten von Patienten mit Osophagitis.