Oxatomide plasma levels in man during chronic dosing.
A study was carried out in 8 subjects to measure plasma levels of oxatomide at defined intervals after chronic dosing with 30 mg twice daily for a period of 22 days. Plasma oxatomide levels were measured by radioimmunoassay. The results showed that mean steady-state plasma levels of 20 to 30 ng/ml just before the next dose and approximately 40 ng/ml 4 hours after a dose were reached by the sixth day of dosing.
D000328:Adult; D005260:Female; D006634:Histamine H1 Antagonists / Q000008:administration & dosage / Q000097:blood*; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000008:administration & dosage / Q000097:blood*
D006634:Histamine H1 Antagonists; D010879:Piperazines; C015408:oxatomide