Intravenous lorazepam in neuroleptic-induced catatonia.
Presented here are four cases of catatonic reactions which were felt to be neuroleptic induced. Intravenous lorazepam was rapidly effective in reversing the catatonia and attendant symptoms. Lorazepam's previous uses and pharmacological profile are discussed. Reviewed briefly are catatonia and its neuroleptic-induced forms. Possible mechanisms responsible for the therapeutic effect of intravenous lorazepam in these cases are then examined.
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000037:antagonists & inhibitors*; D002389:Catatonia / Q000139:chemically induced / Q000188:drug therapy*; D005260:Female; D006220:Haloperidol / Q000009:adverse effects / Q000037:antagonists & inhibitors; D006801:Humans; D007275:Injections, Intravenous; D008140:Lorazepam / Q000627:therapeutic use*; D008297:Male; D013577:Syndrome; D014268:Trifluoperazine / Q000009:adverse effects / Q000037:antagonists & inhibitors
D014150:Antipsychotic Agents; D014268:Trifluoperazine; D006220:Haloperidol; D008140:Lorazepam