Effect of ethyl alcohol infusions on glucose and hormone status in ovine pregnancy.
Term pregnant ewes were given ethanol in dextrose water i.v. according to the usual 2-h loading dose recommended for premature labor. Glucose, insulin, cortisol, progestins, estrone and estradiol in maternal and fetal plasma were measured for 5 h. In both treated animals and controls (dextrose water only) there was reduction in maternal cortisol and a reduction followed by a rise in progesterone concentration. Mean concentration of insulin in maternal plasma across all sampling times was higher in ethanol treated animals.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D004958:Estradiol / Q000097:blood; D004970:Estrone / Q000097:blood; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005947:Glucose / Q000494:pharmacology; D006728:Hormones / Q000097:blood*; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011372:Progestins / Q000097:blood; D012756:Sheep / Q000502:physiology*
D001786:Blood Glucose; D006728:Hormones; D007328:Insulin; D011372:Progestins; D004970:Estrone; D000431:Ethanol; D004958:Estradiol; D005947:Glucose; D006854:Hydrocortisone