title: Clinical assessment of new I.V. sedation agents and techniques.
abstract: The purpose of this paper has been to describe the information that must be gathered before a new drug can be used effectively and safely for I.V. sedation. A new drug, midazolam, has been used as an illustrative example.
mesh_terms: D000766:Anesthesia, Dental / Q000379:methods*; D000771:Anesthesia, Intravenous / Q000379:methods; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001007:Anxiety / Q000517:prevention & control; D001569:Benzodiazepines / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D006321:Heart / Q000187:drug effects; D006801:Humans; D008874:Midazolam; D011229:Preanesthetic Medication / Q000379:methods*; D012119:Respiration / Q000187:drug effects; D013997:Time Factors
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D008874:Midazolam