A comparison of chlormezanone and temazepam in sleep disturbance.
Fifty-five patients complaining of insomnia entered a single-blind general practice study and were treated with either 400 mg chlormezanone or 20 mg temazepam at night for 2 weeks. There was a significant increase from baseline for both treatments in average duration of sleep, quality of sleep and frequency of waking refreshed. There was no significant difference between the treatments, with overall effectiveness rated similarly. It is concluded that chlormezanone is at least as useful as temazepam in treating insomnia.
D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D002720:Chlormezanone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*; D012894:Sleep Stages / Q000187:drug effects; D013693:Temazepam / Q000627:therapeutic use*
D014151:Anti-Anxiety Agents; D013693:Temazepam; D002720:Chlormezanone