Volume of water-filled pores in the ethyl cellulose membrane and the permeability of microcapsules.
The volume fraction of the water-filled pores in the microcapsule membranes was calculated and the values from 0.55 to 2.5% were obtained. Differential scanning calorimetry of aqueous suspensions of microcapsules showed no structured water present in the ethyl cellulose membranes. The temperature effect on the apparent diffusion coefficient of a drug was investigated and the apparent activation energy of diffusion was calculated.
D002151:Calorimetry; D002214:Capsules; D002482:Cellulose / Q000031:analogs & derivatives*; D008567:Membranes, Artificial; D010539:Permeability; D011092:Polyethylene Glycols; D013696:Temperature; D013816:Thermodynamics; D014867:Water
D002214:Capsules; D008567:Membranes, Artificial; D014867:Water; D011092:Polyethylene Glycols; C013517:ethyl cellulose; D002482:Cellulose