title: Acquired immunodeficiency with intestinal cryptosporidiosis: possible transmission by Haitian whole blood.
abstract: A 31-year-old Frenchman had an acquired immunodeficiency syndrome (AIDS) with profound depression of cellular immunity and relative sparing of humoral immunity. The clinical picture included intractable secretory diarrhoea, vomiting, abdominal pain, and weight loss. Gastrointestinal cryptosporidiosis was present and a perfusion technique showed profuse secretion of fluid in the proximal small bowel. The patient also had recurrent Salmonella typhimurium septicaemia, cytomegalovirus infection, and cerebral toxoplasmosis and he died within 13 months. This patient did not belong to any of the groups known to be affected by this type of acquired immunodeficiency (homosexuals, drug addicts, haemophiliacs, Haitians) but had been transfused with Haitian blood 4 years before onset of symptoms. This case supports the notion that some forms of AIDS may be transmitted by blood, with a long incubation period.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000473:pathology / Q000635:transmission*; D000328:Adult; D001921:Brain / Q000473:pathology; D001922:Brain Abscess / Q000276:immunology / Q000469:parasitology; D003044:Coccidia / Q000302:isolation & purification; D003048:Coccidiosis / Q000276:immunology*; D005602:France / Q000208:ethnology; D006205:Haiti; D006801:Humans; D007111:Immunity, Cellular; D007411:Intestinal Diseases, Parasitic / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D007583:Jejunum / Q000473:pathology; D008297:Male; D018805:Sepsis / Q000276:immunology / Q000473:pathology; D013997:Time Factors; D014123:Toxoplasmosis / Q000276:immunology / Q000473:pathology; D065227:Transfusion Reaction