title: Characterization of monoaminergic terminals in the neostriatum of neonatal rats: an electron microscopic morphometric analysis.
abstract: Monoaminergic (MA) boutons in the neostriatum of neonatal rats were studied by using 5-hydroxydopamine. We found: (a) bouton size averaged 0.6 micron in diameter; (b) terminal density was 68 boutons per 7200 micron2 area; (c) synaptic frequency was 33.2%; and (d) MA neurons constituted 9.2% of all boutons. This population was much lower than that reported in immature neocortex where MA neurons are a major innervation.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D003342:Corpus Striatum / Q000033:anatomy & histology* / Q000187:drug effects; D006892:Hydroxydopamines / Q000494:pharmacology; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure; D018377:Neurotransmitter Agents / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000187:drug effects / Q000648:ultrastructure*; D013570:Synaptic Membranes / Q000648:ultrastructure; D013572:Synaptic Vesicles / Q000648:ultrastructure
chemical_list: D006892:Hydroxydopamines; D018377:Neurotransmitter Agents; C027802:5-hydroxydopamine