title: Cinchophen analogues as potential CNS agents.
abstract: Several amides of cinchophen were prepared and evaluated as CNS agents. Compounds III, VII, XII, XIII, and XIV exhibited analgesic activity while I, III, and XIV acted as CNS depressants.
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis*; D000818:Animals; D002492:Central Nervous System Depressants / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D004347:Drug Interactions; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010424:Pentobarbital / Q000494:pharmacology; D011804:Quinolines / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects
chemical_list: D000700:Analgesics; D002492:Central Nervous System Depressants; D011804:Quinolines; D010424:Pentobarbital