Nasal histamine sensitivity in allergic rhinitis.
Our recent studies of nasal histamine sensitivity in nasal allergy are presented. The sensitivity differed according to the site and size of the nasal mucosa and was correlated with the degree of provocation reaction to antigen. This sensitivity appears to be established in childhood and strongly correlated with the increased sensitivity of histamine receptors as well as the autonomic nervous system dysfunction of the nose.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000403:Airway Resistance / Q000187:drug effects; D001507:Beclomethasone / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D004205:Cromolyn Sodium / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000150:complications*; D006632:Histamine / Q000276:immunology*; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009297:Nasal Mucosa / Q000276:immunology; D009299:Nasal Provocation Tests; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications* / Q000188:drug therapy
D006634:Histamine H1 Antagonists; D006632:Histamine; D001507:Beclomethasone; D004205:Cromolyn Sodium