Sudden death and antipsychotic drugs.
Antipsychotic drug use may be associated with clinically significant cardiovascular side effects and rare instances of sudden death. The authors review case reports of patients who suddenly died while taking these drugs and examine possible mechanisms involved. Clinical recommendations for prevention are made and include attention to predisposing medical factors and avoidance of risky drug combinations.
D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001237:Asphyxia / Q000139:chemically induced; D003645:Death, Sudden / Q000209:etiology*; D004562:Electrocardiography; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D001523:Mental Disorders / Q000188:drug therapy*; D010640:Phenothiazines
D014150:Antipsychotic Agents; D010640:Phenothiazines