The pull-up test in rats: a simple method for evaluating muscle relaxation.
A test for muscle relaxation in rats is described. The pull-up test is performed by holding an inverted rat by its hind legs. The time taken by the rat to pull itself up and grasp the hand of the experimenter is used as the test parameter. It is simple and quick and separates muscle relaxation from sedation, catalepsy, and catatonia.
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001463:Barbiturates / Q000494:pharmacology*; D002491:Central Nervous System Agents / Q000494:pharmacology*; D002707:Chlordiazepoxide / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005069:Evaluation Studies as Topic; D008297:Male; D008722:Methods; D009068:Movement; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D011187:Posture; D051381:Rats; D011919:Rats, Inbred Strains
D014151:Anti-Anxiety Agents; D001463:Barbiturates; D002491:Central Nervous System Agents; D002707:Chlordiazepoxide