The role of different K antigens of Escherichia coli in phagocytosis by polymorphonuclear leukocytes.
The importance of K antigens from six strains of Escherichia coli for the interaction with polymorphonuclear leukocytes (PMNL) was studied. The major factor influencing this interaction was the ability of strains to activate complement by the classical route during opsonisation, this process being reduced for most K-positive strains. Interference of K antigens with the functioning of common pili as adhesions of eukaryotic cells was not observed nor a toxic effect of K antigens on PMNL.
D000907:Antibodies, Bacterial / Q000276:immunology; D000941:Antigens / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D000954:Antigens, Surface; D003167:Complement Activation; D003170:Complement Pathway, Alternative; D003171:Complement Pathway, Classical; D003165:Complement System Proteins / Q000276:immunology; D004533:Egtazic Acid; D004926:Escherichia coli / Q000276:immunology*; D010861:Fimbriae, Bacterial / Q000276:immunology; D006386:Hemagglutination Tests; D006358:Hot Temperature; D008163:Luminescent Measurements; D008274:Magnesium; D009504:Neutrophils / Q000276:immunology*; D009895:Opsonin Proteins / Q000276:immunology; D010587:Phagocytosis; D015054:Zymosan
D000907:Antibodies, Bacterial; D000941:Antigens; D000942:Antigens, Bacterial; D000954:Antigens, Surface; C030659:K antigens; D009895:Opsonin Proteins; D004533:Egtazic Acid; D003165:Complement System Proteins; D015054:Zymosan; D008274:Magnesium