The effect of levamisole on gastric ulcers induced in the rat by anti-inflammatory and necrotizing agents.
Levamisole, in doses similar to those required to observe immunostimulation in animals, antagonized dose-dependently, in rats, gastric ulcers produced by necrotizing agents (HCl and ethanol) and NSAIDs (indomethacin and piroxicam) without affecting the anti-inflammatory properties of these latter drugs.
D000818:Animals; D000893:Anti-Inflammatory Agents; D000897:Anti-Ulcer Agents; D000431:Ethanol; D006851:Hydrochloric Acid; D007213:Indomethacin; D007978:Levamisole / Q000494:pharmacology*; D008297:Male; D010894:Piroxicam; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000139:chemically induced; D013843:Thiazines
D000893:Anti-Inflammatory Agents; D000897:Anti-Ulcer Agents; D013843:Thiazines; D010894:Piroxicam; D007978:Levamisole; D000431:Ethanol; D006851:Hydrochloric Acid; D007213:Indomethacin