In vitro effects of reproterol upon tracheo- bronchial, cardiac and cerebral adenylcyclase.
In vitro researches documented that reproterol, as well as salbutamol, is a powerful stimulant of adenyl cyclase activity in the trachea and bronchi but less potent than isoprenaline. The stimulation was antagonized by beta-blockers.
D000262:Adenylyl Cyclases / Q000032:analysis / Q000378:metabolism*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000201:enzymology*; D001980:Bronchi / Q000201:enzymology*; D001993:Bronchodilator Agents / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002645:Chickens; D004338:Drug Combinations; D004789:Enzyme Activation; D007031:Hypothalamus / Q000201:enzymology; D066298:In Vitro Techniques; D009921:Metaproterenol / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000494:pharmacology; D009206:Myocardium / Q000201:enzymology*; D013806:Theophylline / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000494:pharmacology; D014132:Trachea / Q000201:enzymology*
D000319:Adrenergic beta-Antagonists; D001993:Bronchodilator Agents; D004338:Drug Combinations; C014792:reproterol; D009921:Metaproterenol; D013806:Theophylline; D000262:Adenylyl Cyclases