Management of quinine overdose.
The successful management of a case of quinine overdose with blindness is described. From a review of the literature, treatment of moderate poisoning with ingestion of less than 10 g of quinine should consist of immediate and thorough gastric lavage, forced acid diuresis, immediate bilateral stellate ganglion blockage repeated if there is clinical improvement in vision. With a larger overdose or when coma or convulsions occur haemodialysis, peritoneal dialysis or preferably haemoperfusion should be considered.
D000328:Adult; D001766:Blindness / Q000139:chemically induced*; D004232:Diuretics / Q000627:therapeutic use; D004562:Electrocardiography; D005730:Ganglionic Blockers / Q000627:therapeutic use; D005751:Gastric Lavage; D006801:Humans; D008297:Male; D011803:Quinine / Q000506:poisoning*; D013405:Suicide
D004232:Diuretics; D005730:Ganglionic Blockers; D011803:Quinine