Folate levels in patients with ulcerative colitis receiving sulphasalazine.
The question of folate deficiency in patients receiving sulphasalazine is still controversial. A random sample of patients with ulcerative colitis receiving sulphasalazine were studied to determine the clinical significance of the inhibition of folic acid absorption by the drug. No significant lowering of folate levels could be determined.
D003093:Colitis, Ulcerative / Q000097:blood / Q000188:drug therapy*; D004912:Erythrocytes / Q000032:analysis; D005492:Folic Acid / Q000097:blood*; D006801:Humans; D012460:Sulfasalazine / Q000008:administration & dosage / Q000494:pharmacology*
D012460:Sulfasalazine; D005492:Folic Acid