title: Lethal potency in mice of toxins from scorpion, sea anemone, snake and bee venoms following intraperitoneal and intracisternal injection.
abstract: The lethal potency of 29 toxins from scorpion, sea anemone, snake and bee venoms was studied. Lethality following intracisternal injection of these toxins is considerably higher than following i.p. injection (except for the snake neurotoxins). This is of practical interest in the determination of the concentration of active toxins in a solution when only small amounts are available, as in the case of radiolabelled toxins.
mesh_terms: D000818:Animals; D001514:Bee Venoms / Q000633:toxicity*; D002946:Cisterna Magna; D003064:Cnidarian Venoms / Q000633:toxicity*; D004546:Elapid Venoms / Q000633:toxicity; D007267:Injections; D007274:Injections, Intraperitoneal; D007928:Lethal Dose 50; D051379:Mice; D012604:Scorpion Venoms / Q000633:toxicity*; D012615:Sea Anemones; D012910:Snake Venoms / Q000633:toxicity*; D014118:Toxins, Biological / Q000633:toxicity*
chemical_list: D001514:Bee Venoms; D003064:Cnidarian Venoms; D004546:Elapid Venoms; D012604:Scorpion Venoms; D012910:Snake Venoms; D014118:Toxins, Biological