title: [Comparative studies of initial pressure reduction using 0.3% metipranolol and 0.25% timolol in eyes with wide-angle glaucoma].
abstract: In a short-term study the pressure-lowering effects of Metipranolol 0.3% and Timolol 0.25% were compared in eyes with open-angle glaucoma by means of one-drop curves, diurnal pressure curves and tonography. It appears that these two drugs may be regarded as equal in respect of extent and duration of action. Aqueous humor outflow was facilitated slightly by both drugs, although increase was only statistically significant with Metipranolol.
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D014290:Metipranolol / Q000008:administration & dosage*; D008875:Middle Aged; D011412:Propanolamines / Q000008:administration & dosage*; D013997:Time Factors; D013999:Timolol / Q000008:administration & dosage*
chemical_list: D011412:Propanolamines; D013999:Timolol; D014290:Metipranolol
vernacular_title: Vergleichende Untersuchungen über die initiale Drucksenkung durch Metipranolol 0,3% und Timolol 0,25% in Augen mit Weitwinkel-Glaukom.