title: [Local anesthetic action of metipranolol as compared to timolol].
abstract: In a randomized study the local anesthetic side effects of the beta blockers Metipranolol and Timolol were compared. With the new electronic optical esthesiometer accurate, reproducible sensibility measurements are now possible. It can be shown that both beta blockers have a brief local anesthetic effect when applied to the cornea in drop form. There is also a relation between dose and effect.
mesh_terms: D000328:Adult; D000779:Anesthetics, Local; D055598:Chemical Phenomena; D002621:Chemistry; D003315:Cornea / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D006801:Humans; D014290:Metipranolol / Q000494:pharmacology*; D008875:Middle Aged; D009885:Ophthalmology / Q000295:instrumentation; D011412:Propanolamines / Q000494:pharmacology*; D011897:Random Allocation; D013999:Timolol / Q000494:pharmacology*
chemical_list: D000779:Anesthetics, Local; D011412:Propanolamines; D013999:Timolol; D014290:Metipranolol
vernacular_title: Die lokalanästhetische Wirkung von Metipranolol im Vergleich zu Timolol.