Drug interactions in psychopharmacology.
The mechanisms underlying psychotropic drug interactions include alterations in gastrointestinal absorption, protein-binding, specific and nonspecific metabolic degradation, receptor interactions, and renal clearance. The risk of interactions can be minimized by detailed drug history-taking, use of rapid reference sources, patient education, and physician behaviors that include serious attention to somatic complaints, identification of "at risk" situations, and rational prescribing habits.
D000928:Antidepressive Agents / Q000494:pharmacology; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000494:pharmacology; D001463:Barbiturates / Q000494:pharmacology; D001569:Benzodiazepines / Q000494:pharmacology; D002317:Cardiovascular Agents / Q000494:pharmacology; D002697:Chloral Hydrate / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D006919:Hydroxyzine / Q000494:pharmacology; D008094:Lithium / Q000494:pharmacology; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D010640:Phenothiazines / Q000009:adverse effects; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000494:pharmacology*; D012306:Risk
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D001463:Barbiturates; D002317:Cardiovascular Agents; D008996:Monoamine Oxidase Inhibitors; D010640:Phenothiazines; D011619:Psychotropic Drugs; D001569:Benzodiazepines; D006919:Hydroxyzine; D002697:Chloral Hydrate; D008094:Lithium