[Effect of cadmium ions on the bursting electrical activity of an identified neuron in Helix pomatia].
The effect of cadmium ions was studied on electrical activity of RPal bursting neuron of Helix pomatia. It is shown that 1 mM of Cd2+ ions completely blocks the neuronal bursting activity. If the peptidic modulating factor is added to the Cd2+-containing solution, the bursting activity is not blocked but even increases. It is suggested that Cd2+ ions block the neuronal bursting activity by inhibiting the calcium current in presynaptic terminals of a nonidentified peptidergic interneuron which under normal conditions secretes the modulating factor on the RPal neuronal soma eliciting its bursting activity.
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D002118:Calcium / Q000502:physiology*; D005724:Ganglia / Q000502:physiology*; D006372:Helix, Snails; D007395:Interneurons / Q000502:physiology; D009474:Neurons / Q000187:drug effects; D018377:Neurotransmitter Agents / Q000502:physiology; D010455:Peptides / Q000502:physiology
D018377:Neurotransmitter Agents; D010455:Peptides; D002104:Cadmium; D002118:Calcium
Vliianie ionov kadmiia na pachechnuiu élektricheskuiu aktivnost' identifitsirovannogo neĭrona vinogradnoĭ ulitki.