[Effect of high-fat and high-protein diets on the enzyme activity participating in hydrochloric acid secretion].
The authors studied the effect of high-fat and high-protein diets on the activity of some enzymes of rat gastric mucosa parietal cells. It was found that the high-protein diet (40% of protein in terms of caloricity) causes an increase in the activity of both the mitochondrial enzymes of Mg2+-ATPase and HCO-3-ATPase and enzymes of the plasma membrane (K+-ATPase and cytoplasm (carboanhydrase). The high-fat diet (60%) of fat in terms of caloricity) produces different effects on the above-indicated enzymes: the activity of Mg2+-ATPase decreases, while that of HCO-3-ATPase rises; at the same time the activity of K+-ATPase and carboanhydrase diminishes. It was shown that the enzymatic systems responsible for hydrochloric acid secretion in the stomach show a delicate response to a qualitatively different nutrition.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D027321:Anion Transport Proteins; D017301:Ca(2+) Mg(2+)-ATPase; D002256:Carbonic Anhydrases / Q000378:metabolism; D027682:Cation Transport Proteins; D004041:Dietary Fats / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains
D027321:Anion Transport Proteins; D027682:Cation Transport Proteins; D004041:Dietary Fats; D004044:Dietary Proteins; D000251:Adenosine Triphosphatases; D017301:Ca(2+) Mg(2+)-ATPase; C031652:anion-sensitive ATPases; C022761:potassium transporting ATPase; D002256:Carbonic Anhydrases
Vliianie vysokozhirovoĭ i vysokobelkovoĭ diet na aktivnost' nekotorykh fermentov, prinimaiushchikh uchastie v sekretsii solianoĭ kisloty.