[Tardive dyskinesias].
Tardive dyskinesia frequently occur during neuroleptic-treatments. Prevalence and risk factors, clinical characteristics, relation to other extrapyramidal disorders are reviewed. The presumed pathophysiology is that tardive dyskinesia are caused by a neuroleptic-induced dopamine receptor hypersensitivity. Several trials of treatment are compared with respect to this hypothesis.
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects; D003937:Diagnosis, Differential; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000139:chemically induced; D011379:Prognosis; D011950:Receptors, Cholinergic / Q000187:drug effects; D011954:Receptors, Dopamine / Q000187:drug effects; D012306:Risk; D009435:Synaptic Transmission / Q000187:drug effects
D014150:Antipsychotic Agents; D011950:Receptors, Cholinergic; D011954:Receptors, Dopamine
Les dyskinésies tardives.