[In-patient withdrawal treatment of heroin addicts with neuroleptics (author's transl)].
The results are reported of 144 abrupt withdrawal treatment in heroin addicts (102 in males, 42 in females). Neuroleptics were given intravenously (partly via subclavia catheter) or orally and the results compared with one another. Parenteral treatment needed much more specialist supervision and control and had a much higher complication rate. It should be used only on the individual special case. The initial withdrawal lasts about 4 days with an oral dosage of 270 mg levopromazine in males and 240 mg in females or 540 mg chlorprothixene in males and 520 mg in females per 24 hours. The only side effects encountered were tachycardia and the occasional occurrence of extrapyramidal signs. The liver function tests did not show any significant changes during the treatment.
D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002749:Chlorprothixene / Q000627:therapeutic use; D005260:Female; D006556:Heroin Dependence / Q000188:drug therapy*; D006760:Hospitalization; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008728:Methotrimeprazine / Q000627:therapeutic use
D014150:Antipsychotic Agents; D008728:Methotrimeprazine; D002749:Chlorprothixene
Stationäre Entzugsbehandlung Heroinadhängiger mit Neuroleptika.