N-acetylcysteine prevents the doxorubicin-induced decrease of cyclic GMP.
D000111:Acetylcysteine / Q000494:pharmacology*; D000328:Adult; D000368:Aged; D001706:Biopsy; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism*; D004317:Doxorubicin / Q000494:pharmacology*; D004341:Drug Evaluation; D004347:Drug Interactions; D004562:Electrocardiography; D006162:Guanylate Cyclase / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D011897:Random Allocation; D013997:Time Factors
D004317:Doxorubicin; D000242:Cyclic AMP; D006162:Guanylate Cyclase; D006152:Cyclic GMP; D000111:Acetylcysteine