[Radionuclide study of the influence of beta-adrenoblockaders on the cardiotonic effect of cardiac glycosides].
Radiocardiography was used in 234 patients to explore the effect of corglycon, a glycoside drug obtained from Convallaria L., cardiac glycoside (CG) digoxin, beta-adrenoblockers (BAB) anapriline and trasicor, and combinations of CG and BAB on the minute and stroke volumes of the circulation and heart rate. It has been shown that administration of CG coupled with BAB increasing the tolerance to the cardiotoxic effect of CG does not entail a reduction of their beneficial inotropic action.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D001811:Blood Volume Determination / Q000379:methods; D002301:Cardiac Glycosides / Q000627:therapeutic use*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D012711:Serum Albumin, Radio-Iodinated
D000319:Adrenergic beta-Antagonists; D002301:Cardiac Glycosides; D012711:Serum Albumin, Radio-Iodinated
Radionuklidnoe issledovanie vliianiia beta-adrenoblokatorov na kardiotonicheskiĭ éffekt serdechnykh glikozidov.