Scanning with L-(13 N) glutamate: Assessment of the response to chemotherapy of a patient with embryonal rhabdomyosarcoma.
The use of (13) N-labeled L-glutamate as an imaging agent in a patient with embryonal rhabdomyosarcoma is described. Localization of (13)N in a large, poorly defined tumor of the left pectoral region was seen, and clinically occult right axilliary metastases were also detected. A marked reduction in uptake in these areas occurred after chemotherapy, paralleling the clinical disappearance of tumor. These changes were verified on gallium scan. (13)N-labeled glutamate may be useful as an imaging agent, especially in patients with soft-tissue sarcomas.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001365:Axilla; D005971:Glutamates; D018698:Glutamic Acid; D006801:Humans; D008297:Male; D009590:Nitrogen Radioisotopes; D011877:Radionuclide Imaging; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging* / Q000188:drug therapy; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013909:Thorax
D000970:Antineoplastic Agents; D005971:Glutamates; D009590:Nitrogen Radioisotopes; D018698:Glutamic Acid