title: [Intoxication by beta-blockers in children and adolescents (author's transl)].
abstract: After ingestion of beta-blocking agents 20 out of 77 children and adolescents developed clinical symptoms. 11 cases resulted from suicidal attempts. A 15 year old girl died. Neurological signs (12) predominated. Cardiovascular signs (10) were especially seen after suicidal ingestion of beta-blocking agents. Infants frequently showed hypoglycemia or symptoms based on hypoglycemia (6). After elimination from the gastrointestinal tract patients require intensive monitoring as well as symptomatic treatment. Treatment with atropin often gave insufficient results. However, treatment with glucagon was successful. Secondary detoxication generally is not required and must be evaluated after pharmacokinetic data. Forced diuresis is not indicated.
mesh_terms: D000070:Acebutolol / Q000506:poisoning; D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000506:poisoning*; D002675:Child, Preschool; D005260:Female; D005934:Glucagon / Q000627:therapeutic use; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D011433:Propranolol / Q000506:poisoning; D012769:Shock / Q000139:chemically induced / Q000188:drug therapy; D013015:Sotalol / Q000506:poisoning; D013406:Suicide, Attempted
chemical_list: D000319:Adrenergic beta-Antagonists; D000070:Acebutolol; D005934:Glucagon; D011433:Propranolol; D013015:Sotalol
vernacular_title: Vergiftungen mit beta-rezeptorenblockern bei Kindern und Jugendlichen.