Ultrastructural localization of human complement C3b receptors in the human kidney as determined by immunoperoxidase staining with the monoclonal antibody C3RTo5.
The precise localization of human complement C3b receptors in human kidneys was investigated by means of indirect immunoperoxidase staining of frozen kidney sections with the monoclonal antibody C3RT05, which is specific for human C3b receptors. Transmission electron microscopy indicated that C3b receptors are located on the entire cell membrane of the visceral epithelial cells of the glomeruli.
D000911:Antibodies, Monoclonal; D003179:Complement C3b; D004848:Epithelium / Q000032:analysis / Q000276:immunology / Q000648:ultrastructure; D006801:Humans; D007124:Immunoenzyme Techniques; D007678:Kidney Glomerulus / Q000032:analysis / Q000276:immunology / Q000648:ultrastructure*; D011951:Receptors, Complement
D000911:Antibodies, Monoclonal; D011951:Receptors, Complement; D003179:Complement C3b