A cytophotometrical study on the centenarian hepatocyte.
Size alterations, both of cell and nucleus, of the centenarian hepatocyte followed a pattern proportionate to aging which was observed in the hepatocyte of non-centenarian groups and clearly followed nonagenarian in location on the graph. When size alterations of the hepatocyte were considered as an aging parameter, the present observation suggests that the centenarian could be a group next to the nonagenarian. The results obtained by present cytomorphometrical analysis do not favor a hypothesis that the centenarian is a select population in terms of longevity.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D005260:Female; D006801:Humans; D008099:Liver / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D011123:Polyploidy