[Protective effect of phenazepam and sodium oxybutyrate on somatic manifestations in immobilization stress].
The effects of phenazepam and sodium hydroxybutyrate on the somatic manifestations, ultrastructure of the cortex and lipid content of the adrenals in rats exposed to immobilization were examined. Both the drugs had the stress-protective effect, decreasing the stress manifestations at alarm and resistance stages.
D000302:Adrenal Cortex / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000627:therapeutic use*; D006801:Humans; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D007103:Immobilization; D050356:Lipid Metabolism; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012978:Sodium Oxybate / Q000627:therapeutic use*; D013154:Spleen / Q000187:drug effects; D013315:Stress, Psychological / Q000517:prevention & control*; D013950:Thymus Gland / Q000187:drug effects
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D006885:Hydroxybutyrates; D001569:Benzodiazepines; C017928:phenazepam; D012978:Sodium Oxybate
Izuchenie protektivnogo deĭstviia fenazepama i natriia oksibutirata na somaticheskie proiavleniia pri immobilizatsionnom stresse.