Drug selection in the treatment of pregnancy hypertension. A survey.
Effective blood pressure treatment has only been available during the last 20-25 years. Most antihypertensive drugs employed for other hypertensive conditions have also been used in hypertensive states of pregnancy. In this survey, most of the drugs already in use and some new ones are discussed. No special emphasis is placed on the use of drugs in emergency situations. As beta-adrenoceptor blocking drugs are widely used nowadays, the principal differences between some beta-blockers are discussed in detail. A discussion of future requirements in order to get a better picture of the value of antihypertensive drugs completes this survey.
D000311:Adrenal Glands / Q000187:drug effects; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002302:Cardiac Output / Q000187:drug effects; D003981:Diazoxide / Q000494:pharmacology; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006830:Hydralazine / Q000494:pharmacology; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008901:Mineralocorticoids / Q000037:antagonists & inhibitors; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000503:physiopathology; D012964:Sodium / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D008901:Mineralocorticoids; D006830:Hydralazine; D012964:Sodium; D003981:Diazoxide