Vector compatibility of Phlebotomus papatasi dependent on differentially induced digestion.
Infection with Leishmania tropica, a strain specific to the sandfly Phlebotomus papatasi, was inhibited in sandflies fed on turkey blood. Reduction of the parasite number was correlated with the digestive process. A relatively high DNAase level was induced in the gut of the sandfly by the nucleated turkey erythrocytes. This is the first record of vector-pathogen incompatibility, thus induced, and of differentially triggered digestive processes.
D000818:Animals; D003851:Deoxyribonucleases / Q000378:metabolism; D004063:Digestion; D006790:Host-Parasite Interactions; D066298:In Vitro Techniques; D007891:Leishmania / Q000502:physiology*; D010691:Phlebotomus / Q000201:enzymology / Q000469:parasitology*
D003851:Deoxyribonucleases