Identification of abnormal patterns in eye movements of schizophrenic patients.
Using precise infrared recording instrumentation, we measured the eye-movement patterns in six schizophrenic patients who were taking medication and found saccadic intrusions and saccadic smooth-pursuit tracking in three. This defined some of the eye-movement irregularities reported previously by many investigators. A variety of eye-movement functions in addition to smooth pursuit exhibited these abnormalities, including fixation, vergence, and head-eye pursuit. Saccadic intrusions or saccadic pursuit also occurs in a number of neuro-ophthalmologic disorders, and occasionally in healthy normal subjects. Thus, these eye-movement abnormalities do not occur exclusively in schizophrenia.
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D004585:Electrooculography; D005133:Eye Movements; D005403:Fixation, Ocular; D005556:Form Perception; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007259:Infrared Rays; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*
D014150:Antipsychotic Agents