Neuro-pharmacologic studies on neurogenic bladder after radical hysterectomy.
Miction function of patients who had had radical hysterectomy was investigated neuro-pharmacologically. The patients were divided into two groups according to the operation, with or without preservation of the plexus pelvicus, and bladder and urethral functions were compared by the bethanechol test and phentolamine test. The group with transected plexus pelvicus showed neurogenic bladder with impairment of functions of parasympathetic and sympathetic nerves and the preserved group showed much less impairment in functions of both nerves.
D000328:Adult; D018723:Bethanechol; D001626:Bethanechol Compounds; D005260:Female; D006801:Humans; D007001:Hypogastric Plexus / Q000601:surgery; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010646:Phentolamine; D011312:Pressure; D014521:Urethra / Q000502:physiology; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology* / Q000503:physiopathology; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis* / Q000209:etiology
D001626:Bethanechol Compounds; D018723:Bethanechol; D010646:Phentolamine