Varicella-zoster virus RNA in human trigeminal ganglia.
The technique of in situ hybridisation was used to examine human trigeminal ganglia for the presence of varicella-zoster virus (VZV) RNA. The ganglia were removed from fresh cadavers of individuals without a history of current or recent herpes zoster. Of the various types of cell in the ganglia, only the neurons appeared positive for VZV RNA. 0 to 0.3% of neurons were positive for VZV RNA.
D000368:Aged; D002648:Child; D005260:Female; D006562:Herpes Zoster / Q000382:microbiology; D014645:Herpesvirus 3, Human / Q000254:growth & development; D006801:Humans; D008297:Male; D008875:Middle Aged; D009474:Neurons / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral / Q000032:analysis*; D014276:Trigeminal Nerve / Q000382:microbiology*
D012367:RNA, Viral