title: Trypanosoma brucei infection stimulates receptor-mediated phagocytosis by murine peritoneal macrophages.
abstract: Trypanosoma brucei infection results in hypertrophy of the reticuloendothelial system. Peritoneal macrophages from infected mice were larger, spread out more on glass, and had increased receptor-mediated phagocytic activity both for C3b-and immunoglobulin G-coated erythrocytes. These observations suggest that macrophages were activated as a result of this infection.
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D005260:Female; D007074:Immunoglobulin G / Q000276:immunology; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology; D051379:Mice; D010587:Phagocytosis; D011951:Receptors, Complement; D011961:Receptors, Fc; D014353:Trypanosomiasis, African / Q000276:immunology* / Q000662:veterinary*
chemical_list: D007074:Immunoglobulin G; D011951:Receptors, Complement; D011961:Receptors, Fc