title: Adhesion induction by suture of varying tissue reactivity and caliber.
abstract: The importance of suture size and chronic reactivity in adhesion induction was evaluated in two experiments. In experiment I interrupted sutures (4/0 chromic, 4/0 polyglactin, and 6/0 polyglactin) were placed in the dorsal surfaces of rabbit uterine horns. Adhesions were infrequently induced by all suture materials. In experiment II 4-cm-long incisions were made in the distal antimesenteric uterine horns. These were then reapproximated with running sutures (4/0 chromic, 4/0 polyglactin, 6/0 polyglactin, and 8/0 nylon). Adhesion formation occurred to 16 of 18 incisions closed with 4/0 or 6/0 suture, whereas none of five incisions closed with 8/0 suture formed adhesions. These observations suggest that suture size rather than tissue reactivity is paramount in adhesion induction.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D011183:Postoperative Complications; D011817:Rabbits; D013536:Suture Techniques; D000267:Tissue Adhesions / Q000209:etiology; D014591:Uterine Diseases / Q000209:etiology*; D014599:Uterus / Q000601:surgery