[Estimations of the serum levels of sulfapyridine on patients treated with sulfasalazin (author's transl)].
Estimations of the serum level of sulfapyridine in 21 patients suffering from colitis ulcerosa or Crohn's disease, have been carried out. Nearly 50 per cent of all the serum levels were within the therapeutic range between 20 and 50 micrograms/ml. Some factors influencing the sulfasalazine metabolism are mentioned. The estimation of the serum levels of sulfapyridine is a suitable method for supervision of patients receiving treatment with sulfasalazine.
D000328:Adult; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003424:Crohn Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D013424:Sulfanilamides / Q000097:blood*; D013427:Sulfapyridine / Q000097:blood*; D012460:Sulfasalazine / Q000378:metabolism / Q000627:therapeutic use*
D013424:Sulfanilamides; D012460:Sulfasalazine; D013427:Sulfapyridine
Serumsulfapyridinspiegel-Bestimmungen bei Patienten unter einer Sulfasalazin-Behandlung.