title: Use of lorazepam as a premedicant for caesarean section. An evaluation of its effects on the mother and the neonate.
abstract: The effects of lorazepam premedication on the mother and baby were compared with those of a placebo in a double-blind study of 10 patients undergoing elective Caesarean section. There was little anxiolytic effect on the mothers, and no harmful effects to the babies occurred in respect of blood-gas tensions, heart rate, temperature or feeding patterns. Lorazepam did produce a transient effect on the neonatal respiratory rate and initially the babies had a reduced score on the Brazelton Assessment System.
mesh_terms: D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001007:Anxiety / Q000187:drug effects; D001034:Apgar Score; D001784:Blood Gas Analysis; D001831:Body Temperature / Q000187:drug effects; D002585:Cesarean Section; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D008140:Lorazepam / Q000494:pharmacology; D011939:Mental Recall / Q000187:drug effects; D011229:Preanesthetic Medication; D011247:Pregnancy; D012119:Respiration / Q000187:drug effects
chemical_list: D014151:Anti-Anxiety Agents; D008140:Lorazepam