title: [Metipranolol in the prevention of intraocular pressure elevation after cataract extraction].
abstract: Elevated intraocular pressure during the first few days after routine intracapsular cataract extraction with and without alpha-chymotrypsin is a well-known symptom. A prospective, double-blind study was conducted to determine whether Metipranolol would prevent this increase in pressure. In 40 eyes which underwent routine, uncomplicated cataract extraction a drop of either Metipranolol 0,6% or placebo was administered before and during the first days after surgery. Prophylactic Metipranolol 0,6% can substantially reduce the incidence of severe early postoperative ocular hypertension.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D002387:Cataract Extraction; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D014290:Metipranolol / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000188:drug therapy; D011412:Propanolamines / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D009883:Ophthalmic Solutions; D011412:Propanolamines; D014290:Metipranolol
vernacular_title: Metipranolol zur Prophylaxe einer Augeninnendrucksteigerung nach Kataraktextraktion.