Myocardial calcium levels in furazolidone-induced cardiomyopathy in turkey poults.
Myocardial calcium levels were measured in control turkey poults and in poults with furazolidone (FZ)-induced cardiomyopathy. FZ at a dose of 700 ppm added to the feed of poults from 2 to 5 weeks post-hatching produced the typical round-heart syndrome but had little effect on the calcium levels in the myocardium. Data suggest that the mechanism of FZ cardiotoxicity is not associated with calcium overload.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D009202:Cardiomyopathies / Q000139:chemically induced / Q000378:metabolism / Q000662:veterinary*; D005664:Furazolidone / Q000009:adverse effects*; D009206:Myocardium / Q000378:metabolism*; D011201:Poultry Diseases / Q000139:chemically induced / Q000378:metabolism*; D014422:Turkeys / Q000378:metabolism*
D005664:Furazolidone; D002118:Calcium