title: The effects of beta-blocker therapy on diurnal variation of blood pressure.
abstract: Plotting hourly mean blood pressures recorded continuously by an intra-arterial technique in fully ambulant subjects on a time scale has clearly outlined a circadian biorhythm which is a useful tool for the study of antihypertensive drugs. Studies with beta-adrenoreceptor blocking drugs have shown differences which may have fundamental significance in the clinical usage of these drugs for treating hypertension.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods; D002940:Circadian Rhythm; D004341:Drug Evaluation / Q000592:standards; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists