Malacoplakia of the bladder: a case report of resolution with bethanechol, trimethoprim-sulfamethoxazole and ascorbic acid.
Malacoplakia is a granulomatous disease that most frequently involves the urinary tract but also may involve the genital tract, gastrointestinal tract and retroperitoneum. It is believed to be infectious in origin, secondary to a deficiency of intracellular lysosomal digestion, and heretofore considered a chronic problem. We report a case of malacoplakia of the bladder, which was treated successfully with a combination of bethanechol, trimethoprim-sulfamethoxazole and ascorbic acid.
D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage*; D001205:Ascorbic Acid / Q000008:administration & dosage*; D018723:Bethanechol; D001626:Bethanechol Compounds / Q000008:administration & dosage*; D004338:Drug Combinations / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008287:Malacoplakia / Q000188:drug therapy*; D008875:Middle Aged; D013420:Sulfamethoxazole / Q000008:administration & dosage*; D014295:Trimethoprim / Q000008:administration & dosage*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D001745:Urinary Bladder Diseases / Q000188:drug therapy*
D000892:Anti-Infective Agents, Urinary; D001626:Bethanechol Compounds; D004338:Drug Combinations; D018723:Bethanechol; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole; D001205:Ascorbic Acid