Storage and release of catecholamines by nervous endings in the isolated heart of the eel (Anguilla anguilla L.).
Experiments performed on isolated perfused hearts of the eel (Anguilla anguilla L.) showed that the heart spontaneously released catecholamines (i.e. Adrenaline, Noradrenaline, Dopamine) suggesting that they take part in the cardiac regulation. Stimulation of cardiac vagus branches significantly increased catecholamines levels, measured in a perfusion medium and simultaneously the heart rate and the systolic pressure. The effect of Desmethylimipramine showed that the catecholamines were released from nervous endings and not from endothelial cells.
D000200:Action Potentials; D000811:Anguilla / Q000502:physiology*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000378:metabolism*; D003891:Desipramine / Q000494:pharmacology; D004558:Electric Stimulation; D006321:Heart / Q000294:innervation* / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D009411:Nerve Endings / Q000378:metabolism*; D010477:Perfusion; D011433:Propranolol / Q000494:pharmacology; D013599:Systole; D014630:Vagus Nerve / Q000502:physiology
D002395:Catecholamines; D001285:Atropine; D011433:Propranolol; D003891:Desipramine