title: Post-natal development of TH-like immunoreactivity in the rat retina.
abstract: The post-natal development of catecholaminergic neurons has been studied in the rat retina, using tyrosine-hydroxylase immunohistochemistry. The first TH-like immunoreactive cells were observed by the third post-natal day. The differentiation of neurons and the development of their processes continued until and after, the opening of the eyes (14-15th post-natal day). The catecholaminergic system was fully developed by three weeks of age. The use of retinal flat mounts treated with PAP-immunoperoxidase technique allowed a morphological observation of TH-like immunoreactive whole neurons.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D002454:Cell Differentiation; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D009474:Neurons / Q000201:enzymology / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000166:cytology / Q000254:growth & development*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*
chemical_list: D002395:Catecholamines; D014446:Tyrosine 3-Monooxygenase