A novel mode of neurotoxin action. A polypeptide toxin isolated from Anemonia sulcata shifts the voltage dependence of the maximal rate of rise of Na+ action potentials in a mouse neuronal clone.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002454:Cell Differentiation; D002463:Cell Membrane Permeability / Q000187:drug effects; D002999:Clone Cells; D003064:Cnidarian Venoms / Q000494:pharmacology*; D007473:Ion Channels / Q000187:drug effects; D051379:Mice; D009374:Neoplasms, Experimental / Q000503:physiopathology; D009447:Neuroblastoma / Q000503:physiopathology; D009474:Neurons / Q000502:physiology*; D009498:Neurotoxins / Q000494:pharmacology*; D012964:Sodium / Q000502:physiology*
D003064:Cnidarian Venoms; D007473:Ion Channels; D009498:Neurotoxins; C028800:toxin II (Anemonia sulcata); D012964:Sodium