Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2-receptor antagonists.
D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002927:Cimetidine / Q000494:pharmacology; D013196:Dihydrotestosterone / Q000378:metabolism; D004285:Dogs; D005744:Gastric Acid / Q000378:metabolism*; D006168:Guinea Pigs; D006635:Histamine H2 Antagonists / Q000138:chemical synthesis*; D066298:In Vitro Techniques; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D051381:Rats; D013237:Stereoisomerism; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D014508:Urea / Q000031:analogs & derivatives*; D014961:X-Ray Diffraction
D006635:Histamine H2 Antagonists; D013830:Thiadiazoles; D013196:Dihydrotestosterone; D002927:Cimetidine; D014508:Urea