Effects of 5-HT serotonin on spontaneous locomotor activity of eels.
The swimming activity of eels maintained in tap water at 8-12 degrees C is significantly decreased after i.p. para-chlorophenylalanine (pCPA) administration at dose of 200 mg/kg (p less than 0.005 to respective control value). 5-Hydroxytryptophan (5-HTP) restored transitory swimming activity of eels. These results suggest that 5-HT has an important part in locomotor activity of eels.
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D004524:Eels / Q000502:physiology*; D010134:Fenclonine / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology*; D013997:Time Factors
D012701:Serotonin; D006916:5-Hydroxytryptophan; D010134:Fenclonine