The effects of adrenal hormones, endotoxin and turpentine on serum components of the plaice (Pleuronectes platessa L.).
1. Within 24 hr of injection into plaice, cortisol, deoxycorticosterone, adrenalin or endotoxin cause an increase (P less than 0.001) in circulating C-reactive protein (CRP). Turpentine and soluble dexamethasone have no effect. 2. The increase in CRP with endotoxin is not enhanced with adrenalin or deoxycorticosterone, and in conjunction with cortisol the increase is additive. 3. Changes in CRP are independent of the amounts of serum amyloid P-component or total protein. 4. Turpentine, cortisol and adrenalin cause a rapid increase in circulating glucose. 5. It is concluded that some adrenal hormones stimulate the CRP acute phase response in plaice, without an apparent provoking agent.
D000305:Adrenal Cortex Hormones / Q000494:pharmacology*; D000682:Amyloid / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002097:C-Reactive Protein / Q000096:biosynthesis; D003402:Creatine Kinase / Q000097:blood; D004731:Endotoxins / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology*; D005399:Fishes / Q000097:blood*; D006454:Hemoglobins / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000097:blood; D000683:Serum Amyloid P-Component; D013997:Time Factors; D014425:Turpentine / Q000494:pharmacology*
D000305:Adrenal Cortex Hormones; D000682:Amyloid; D001786:Blood Glucose; D004731:Endotoxins; D006454:Hemoglobins; D000683:Serum Amyloid P-Component; D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D014425:Turpentine; D004837:Epinephrine