New method for administration of hydrochloric acid in metabolic alkalosis.
In a new method for peripheral intravenous infusion of hydrochloric acid the HCl is buffered in an aminoacid solution and infused with a fat emulsion. The aminoacids and the fat emulsions are stable in the presence of HCl, and the transfusion set is resistant to the chemical actin of 0.15 mol/l HCl. Two case-reports show that HCl can be administered safely through a peripheral vein.
D000471:Alkalosis / Q000097:blood / Q000188:drug therapy*; D000596:Amino Acids / Q000008:administration & dosage; D001639:Bicarbonates / Q000097:blood; D002021:Buffers; D004355:Drug Stability; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006851:Hydrochloric Acid / Q000008:administration & dosage* / Q000627:therapeutic use; D006863:Hydrogen-Ion Concentration; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D012996:Solutions
D000596:Amino Acids; D001639:Bicarbonates; D002021:Buffers; D005217:Fat Emulsions, Intravenous; D012996:Solutions; D006851:Hydrochloric Acid