[Drug interactions as a cause for iatrogenic diseases in the aged. A tabulated presentation].
Drug interactions are found in elderly patients to a higher degree than in younger persons, because of the multimorbidity in the advanced age. The reasons are pharmacokinetic and/or pharmacodynamic mechanisms. At the first glance the amount of interactions seems puzzling but after regarding details more thoroughly it turns out that most of those interactions may be attributed to just a few drugs.
D000368:Aged; D000428:Alcohol Drinking; D001667:Binding, Competitive; D001798:Blood Proteins / Q000378:metabolism; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D000431:Ethanol / Q000378:metabolism; D006801:Humans; D007049:Iatrogenic Disease / Q000139:chemically induced*; D010672:Phenytoin / Q000378:metabolism; D011485:Protein Binding; D011955:Receptors, Drug / Q000378:metabolism; D014018:Tissue Distribution; D014044:Tolbutamide / Q000378:metabolism; D014859:Warfarin / Q000378:metabolism
D001798:Blood Proteins; D011955:Receptors, Drug; D000431:Ethanol; D014859:Warfarin; D010672:Phenytoin; D014044:Tolbutamide
Arzneimittelinteraktionen als Ursache für iatrogene Erkrankungen im Alter. Eine'tabellarische Zusammenstellung.