Sulphasalazine-induced systemic lupus erythematosus in a child.
A case is reported of lupus syndrome in a 13-year-old girl with ulcerative colitis treated with sulphasalazine. She had antibodies to nuclear factor and double-stranded DNA. The clinical pattern resembled drug-induced systemic lupus erythematosus and has resolved since her sulphasalazine was discontinued. Sulphasalazine-induced lupus syndrome has never been reported in a child. The history illustrates the role of sulphasalazine in the development of this syndrome.
D000293:Adolescent; D000367:Age Factors; D003093:Colitis, Ulcerative / Q000188:drug therapy; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D012460:Sulfasalazine / Q000009:adverse effects* / Q000627:therapeutic use
D012460:Sulfasalazine