Long survival following combined treatment of inoperable cholangiocarcinoma: surgery, radiotherapy, and chemotherapy.
A jaundiced patient due to inoperable bile duct carcinoma was treated by a combination of surgery, radiotherapy, and chemotherapy. At the operation an intra-abdominal, extra-choledochal bypass of the tumor was performed with a T-tube obstruction 10 months after diagnosis, and no evidence of malignancy was seen. The T-tube was replaced by an Argyle tube. One year later jaundice reappeared, due to displacement of the tube, and islets of metastatic tumor ce and additional cytotoxic treatment was given. Three months later, after the patient's demise due to an unrelated cause, no evidence of the disease was found. This case demonstrates the importance of palliative by-passing of the tumor in order to relieve obstruction, thus enabling further oncological treatment, which may be, as in the present case, highly effective.
D002759:Adenoma, Bile Duct / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D001650:Bile Duct Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D004322:Drainage; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007565:Jaundice / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010166:Palliative Care
D003037:Cobalt Radioisotopes; D003520:Cyclophosphamide; D005472:Fluorouracil