[Effects of acute or chronic poisoning with lindane or 2,4,5-trichlorophenoxyacetic acid on adrenal and urinary catecholamines of rats. Effect of a hypo- and hyperlipidic diet].
Acute intoxication of adult female rats by an injection of 15 mg of Lindane or 25 mg of 2-4-5 T induces, in one hour, as decrease in the adrenal epinephrine level and an increase in the urinary excretion of this hormone. These modifications are absent after chronic intoxication by these pesticides added in the food (60 and 100 ppm respectively), under normal, hypo- and hyperlipidic diet.
D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000506:poisoning*; D000208:Acute Disease; D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D002908:Chronic Disease; D004041:Dietary Fats / Q000494:pharmacology*; D004837:Epinephrine / Q000378:metabolism* / Q000652:urine; D005260:Female; D001556:Hexachlorocyclohexane / Q000506:poisoning*; D009638:Norepinephrine / Q000378:metabolism / Q000652:urine; D051381:Rats
D004041:Dietary Fats; D001556:Hexachlorocyclohexane; D015085:2,4,5-Trichlorophenoxyacetic Acid; D009638:Norepinephrine; D004837:Epinephrine
Effets de l'intoxication aiguë ou chronique par le lindane ou l'acide trichloro 2,4,5 phénoxyacétique sur les catécholamines surrénaliennes et urinaires du rat. Influence d'un régime hypo- et hyperlipidique.