[Protective effect of interferon on the target cells of cytotoxic lymphocytes].
Interferon treatment of sensitized T lymphocytes enhances cytotoxicity against target cells. On the contrary, the same treatment of the target cells alone protects them, whatever the cytotoxicity of effector cells might be. We suggest that the cells having once survived contact with cytotoxic T lymphocytes could become resistant to any new attack by the same cells.
D000818:Animals; D002417:Cattle; D002472:Cell Transformation, Viral; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D000882:Haplorhini; D006801:Humans; D006822:Hybrid Cells; D007372:Interferons / Q000494:pharmacology*; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D013539:Simian virus 40
D007372:Interferons
Effet protecteur de l'interféron sur les cellules cibles de lymphocytes cytotoxiques.