Human leukocyte and fibroblast interferons are structurally related.
The coding sequences of the dDNAs of cloned human leukocyte interferon I and human fibroblast interferon show homologies of 45% at the nucleotide and 29% at the amino acid level. We conclude that the two genes were derived from a common ancestor.
D000595:Amino Acid Sequence; D001483:Base Sequence; D004274:DNA, Recombinant; D005347:Fibroblasts / Q000502:physiology*; D005796:Genes; D006801:Humans; D007372:Interferons / Q000235:genetics*; D007962:Leukocytes / Q000502:physiology*; D012333:RNA, Messenger / Q000235:genetics
D004274:DNA, Recombinant; D012333:RNA, Messenger; D007372:Interferons