Preparation of alkoxyquinoline derivatives and their evaluation as potential central nervous system stimulants.
A variety of substituted amides of 6,7-dimethoxy-2-hydroxyquinoline-3-carboxylic acid were synthesized. Three of these compounds, tested as potential central nervous system stimulants, showed no marked biological activity.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D051379:Mice; D008996:Monoamine Oxidase Inhibitors / Q000138:chemical synthesis; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology
D000697:Central Nervous System Stimulants; D008996:Monoamine Oxidase Inhibitors; D011804:Quinolines