title: Long-term treatment of hypertensive with methyldopa. VI. Patient with target organ disease.
abstract: In a study conducted retrospectively, the incidence of new hypertension-associated complications was low during administration of methyldopa as part of a total antihypertensive regimen in 435 patients with essential hypertension. Antihypertensive therapy was not associated with further morbid events among patients with a pretreatment history of myocardial infarction or stroke.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002561:Cerebrovascular Disorders / Q000517:prevention & control; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D007676:Kidney Failure, Chronic / Q000188:drug therapy; D008297:Male; D008750:Methyldopa / Q000627:therapeutic use*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000517:prevention & control; D012189:Retrospective Studies
chemical_list: D008750:Methyldopa