The effect of zinc-protamine-glucagon in acute pancreatitis.
A double blind study testing the effect of long-acting zinc-protamine-glucagon (7.5 mg every 12 hours for 4--5 days) was carried out in acute pancreatitis. There were 32 patients in ZP-glucagon- and 39 patients in the placebo group. The results show that glucagon had a slightly favourable effect on the general clinical course of the disease but they do not give enough evidence for routine use of glucagon in pancreatitis.
D000208:Acute Disease; D000328:Adult; D000681:Amylases / Q000652:urine; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005934:Glucagon / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000188:drug therapy*; D011479:Protamines / Q000627:therapeutic use*; D015032:Zinc / Q000627:therapeutic use*
D011479:Protamines; D005934:Glucagon; D000681:Amylases; D015032:Zinc