title: alpha 1-Microglobulin.
abstract: A new low-molecular weight plasma protein was discovered and isolated from human urine by Ingemar Beggård. He named it alpha 1-microglobulin. The protein has a molecular weight of 26,000, contains about 20% carbohydrate, is electrophoretically heterogenous, carries a brown-coloured, unidentified substance, and is present in serum in free, as well as in high molecular weight complexes. alpha 1-Microglobulin seems to interfere with the in vitro response of lymphocytes to some antigens. The site of synthesis of alpha 1-microglobulin is unclear.
mesh_terms: D000510:Alpha-Globulins / Q000276:immunology / Q000302:isolation & purification / Q000652:urine*; D000595:Amino Acid Sequence; D000818:Animals; D001826:Body Fluids / Q000378:metabolism; D002105:Cadmium Poisoning / Q000378:metabolism*; D006168:Guinea Pigs; D006801:Humans; D007526:Isoelectric Point; D008221:Lymphoid Tissue / Q000378:metabolism; D008970:Molecular Weight; D014018:Tissue Distribution
chemical_list: D000510:Alpha-Globulins