Food allergy in migraine. Study of dietary exclusion and RAST.
Two-thirds of severe migraineurs were allergic to certain foods, shown by dietary exclusion and subsequent challenge. Radioallergosorbent test confirmed the relevance of these foods. Oral sodium cromoglycate protected these patients from food challenges. The initial specific allergic reaction in the gut may result in increased mucosal permeability which allows food antigens, complexes, or mediators to be absorbed and cause symptoms.
D000941:Antigens / Q000276:immunology; D004205:Cromolyn Sodium / Q000627:therapeutic use; D000939:Epitopes; D005512:Food Hypersensitivity / Q000150:complications* / Q000175:diagnosis / Q000517:prevention & control; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008881:Migraine Disorders / Q000178:diet therapy / Q000209:etiology*; D011852:Radioallergosorbent Test / Q000379:methods*; D011863:Radioimmunoassay / Q000379:methods*
D000941:Antigens; D000939:Epitopes; D007073:Immunoglobulin E; D004205:Cromolyn Sodium