Intra-arterial chemotherapy for patients with inoperable carcinoma of the pancreas.
Percutaneous intra-arterial chemotherapy followed by intravenous maintenance therapy has been given to a highly selected group of 63 patients with inoperable carcinoma of the pancreas in most of whom the predominant symptom was pain. Relief of pain was an immediate response in 55%, with a slow recurrence of symptoms. Low toxicity was observed, with only one death attributable to the form of therapy used.
D000230:Adenocarcinoma / Q000188:drug therapy*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007261:Infusions, Intra-Arterial; D010166:Palliative Care; D010190:Pancreatic Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents; D005472:Fluorouracil