title: [Organization of genes (author's transl)].
abstract: The organization of genes of animal cells is discussed. The genes for 5S-RNA, rRNA and for histones are examples of the organization of repetitive genes. The interruptions of the coding sequence of the mouse beta-globin gene illustrates the split nature of many eukaryotic genes. It is shown that changes in the organization of genes do occur during the normal development of an organism. The methods used for the analysis of gene structure are of great importance for elucidation of the molecular basis of genetic diseases like the thalassemias.
mesh_terms: D002478:Cells, Cultured; D004247:DNA / Q000502:physiology; D005796:Genes; D005815:Genetic Code; D006657:Histones / Q000235:genetics; D006801:Humans; D009690:Nucleic Acid Conformation; D012313:RNA / Q000096:biosynthesis; D012335:RNA, Ribosomal / Q000096:biosynthesis; D013789:Thalassemia / Q000235:genetics
chemical_list: D006657:Histones; D012335:RNA, Ribosomal; D012313:RNA; D004247:DNA
vernacular_title: Organisation von Genen.