Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells.
D000818:Animals; D003208:Concanavalin A / Q000494:pharmacology; D003602:Cytotoxicity, Immunologic; D000939:Epitopes; D006825:Hybridomas / Q000276:immunology; D007375:Interleukin-1; D007376:Interleukin-2 / Q000494:pharmacology*; D008213:Lymphocyte Activation; D008222:Lymphokines / Q000494:pharmacology*; D008285:Major Histocompatibility Complex / Q000528:radiation effects; D051379:Mice; D008805:Mice, Inbred A; D008809:Mice, Inbred C3H; D008811:Mice, Inbred DBA; D011506:Proteins / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors
D000939:Epitopes; D007375:Interleukin-1; D007376:Interleukin-2; D008222:Lymphokines; D011506:Proteins; D003208:Concanavalin A