HLA antigen frequencies in patients with Huntington's chorea and their relatives.
Twenty patients with Hungtington's chorea and 30 family members were typed for 30 antigens of the HLA-A, B, and C series. There was an increased frequency of HLA-BW 16, significant at the 1%-level. After correcting for multiple inferences, the association of HLA-BW 16 with Huntington's chorea was no longer statistically significant. There was also no reliable indication of coupling between HLA antigens and Huntington's chorea in the family studies.
D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D006816:Huntington Disease / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype
D006680:HLA Antigens