title: Photocoagulation for optic disc new vessels in diabetes mellitus.
abstract: The effects of treatment by argon laser and xenon arc photocoagulation in 165 diabetic patients with optic disc new vessel formation have been studied retrospectively. Visual acuity and degree of new vessel formation have been assessed over a period of between six months and seven years of follow-up (mean 23 months). Visual acuity improved in 36% of treated eyes and remained unchanged in 34%. Improvement was most marked in those with initially poor acuity (less than 6/36). There was no association between improvement in visual acuity and regression of disc vessels, the latter occurring in 79% of treated eyes. Only 6% of eyes became blind during the period of follow-up, principally as a result of vitreous haemorrhage and retinal detachment. There was no difference between the results produced by the use of separate or combined argon laser and xenon arc photocoagulation on the regression of disc new vessels. However, our results suggest that argon laser treatment was more effective than xenon arc photocoagulation in improving visual acuity. These findings suggest that either form of treatment or a combination offers considerable benefit in the management of proliferative diabetic retinopathy, even when very severe at presentation.
mesh_terms: D000328:Adult; D000368:Aged; D001128:Argon; D003930:Diabetic Retinopathy / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D007834:Lasers / Q000379:methods*; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D009898:Optic Disk / Q000098:blood supply; D011379:Prognosis; D012171:Retinal Vessels / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D014792:Visual Acuity; D014978:Xenon
chemical_list: D014978:Xenon; D001128:Argon