title: [Dynamics of quantitative RNA changes in the Purkinje cells of the rat cerebellum in various functional states].
abstract: UV cytophotometry was used to study over time the effect of vestibular stimulation on RNA content in Purkinje's cells of the rat cerebellum nodulus. The animals placed in narrow boxes were rotated horizontally (60 r.p.m.) for an hour. To evaluate partially the effects of stress and hypoxia, the content of RNA was examined in the immobilized animals placed in the same boxes without rotation. Rhythmic quantitative changes in RNA in the cytoplasm and nucleus of Purkinje cells were observed upon vestibular stimulation of cerebellum function. In the nucleolus, the changes in the content of RNA were less pronounced. The periodic quantitative changes in the content of RNA in the cytoplasm, nucleus and nucleolus of Purkinje cells were statistically significant in the majority of the animals, but weakly pronounced.
mesh_terms: D000818:Animals; D002466:Cell Nucleolus / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D002531:Cerebellum / Q000502:physiology*; D003593:Cytoplasm / Q000378:metabolism; D008297:Male; D011689:Purkinje Cells / Q000378:metabolism*; D012313:RNA / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D012399:Rotation; D013997:Time Factors
chemical_list: D012313:RNA
vernacular_title: Dinamika kolichestvennykh izmenenii RNK v kletkakh Purkin'e mozzhechka krys pri razlichnykh funktsional'nykh sostoianiiakh.