title: A comparative study on basophil histamine release and skin testing in children with allergic rhinitis.
abstract: Skin tests and histamine release from basophils induced by the same allergens in children with allergic rhinitis were compared. A qualitative correlation between these two tests was found. Basophil histamine release either spontaneous or allergen-induced during the period of developed allergic symptoms was markedly higher as compared with that in a period of clinical remission. It is concluded that basophil histamine release might be a valuable diagnostic method for detection of allergen(s) responsible for symptoms of allergic rhinitis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000494:pharmacology; D001491:Basophils / Q000378:metabolism*; D002648:Child; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000378:metabolism*; D012882:Skin Tests
chemical_list: D000485:Allergens