title: [Clinical trial of nose drops which counteract swelling in rhinitis. Comparative double blind trial].
abstract: In a randomized double-blind study involving 64 patients with impaired nasal breathing, a comparison was made of a single dose each of Farial and xylometazoline-containing nose drops with respect to effectiveness and tolerance. The assessment of the anterior rhinomanometric measurements, which were carried out on 64 patients for a period of 8 hours, showed that both preparations had effected a significant subsidence of the swelling. There were no statistically significant differences in effectiveness, both with regard to intensity and duration. Neither of the preparations caused reactive hyperemia. The patients' subjective reports on the improvement of their nasal breathing correlated widely with the measured values. Local tolerance was good; systemic side effects did not occur.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014663:Nasal Decongestants / Q000627:therapeutic use*; D012123:Pulmonary Ventilation / Q000187:drug effects; D012220:Rhinitis / Q000188:drug therapy*
chemical_list: D014663:Nasal Decongestants
vernacular_title: Zur klinischen Prüfung von abschwellenden Nasentropfen bei Rhinitis. Vergleichende Doppelblind-Prüfung.