Spontaneous cell-mediated cytotoxicity (SCMC) in patients with alopecia universalis.
The spontaneous cell-mediated cytotoxicity (SCMC) of unfractionated lymphocytes was determined in 5 patients with alopecia universalis (AU). The target cells used were K562 and Chang cell lines. All patients had an increased SCMC as compared with age- and sex-matched donors. The results indicate that SCMC against K562 cells is more pronounced than that against Chang cells.
D000328:Adult; D000505:Alopecia / Q000276:immunology*; D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid; D008099:Liver; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged