Production of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.
Thirteen monoclonal antibodies to human leukocyte interferon have been obtained. They exhibit different patterns of binding to purified leukocyte interferon species that are consistent with the structural multiplicity of the human leukocyte interferons. These antibodies will be useful as probes into the structure of the human leukocyte interferons, for their purification, and for rapid assay of leukocyte interferon.
D000818:Animals; D000906:Antibodies; D000936:Antigen-Antibody Complex; D002459:Cell Fusion; D002460:Cell Line; D002478:Cells, Cultured; D002999:Clone Cells; D005260:Female; D006801:Humans; D006822:Hybrid Cells / Q000276:immunology*; D007372:Interferons / Q000096:biosynthesis / Q000276:immunology*; D007962:Leukocytes / Q000378:metabolism*; D051379:Mice; D008815:Mice, Inbred Strains; D010954:Plasmacytoma
D000906:Antibodies; D000936:Antigen-Antibody Complex; D007372:Interferons