title: Rat ovarian mast cells: distribution and cyclic changes.
abstract: Numerous tissue mast cells are present in the ovarian medulla and hilus and in the oviduct of rats. In the medulla, most of these mast cells are in the connective tissue of the stroma near blood and lymphatic vessels. During proestrus, many of the medullary mast cells totally degranulate and thus are not visible histochemically; they then regranulate during estrus. In contrast, the number of stainable mast cells in the ovarian hilus and oviduct does not change during the estrous cycle. Histofluorometric methods demonstrate that mast cells in the ovarian medulla and hilus, as well as the oviduct, contain histamine. In addition, the lining of small blood vessels in the ovarian medulla contains histamine. Thus, mast cell and blood vessel histamine secretion may play a role in ovarian function.
mesh_terms: D000818:Animals; D004971:Estrus; D005260:Female; D006636:Histamine Release; D007986:Luteinizing Hormone / Q000502:physiology; D008407:Mast Cells / Q000166:cytology* / Q000378:metabolism; D010053:Ovary / Q000166:cytology*; D011247:Pregnancy; D051381:Rats
chemical_list: D007986:Luteinizing Hormone