[Parenteral use of an immobilized microbial protease in the combined treatment of experimental peritonitis].
The experimental fecal peritonitis was induced in 70 immature rabbits and the effect of a new enzyme -- "immobilized" terrilythin -- and its combinations with ampicillin upon the development of the pathological process was studied. The efficiency of an associated repeated employment of the "immobilized" terrilythin and ampicillin in experimental peritonitis has been demonstrated which was supported by higher survival and longer life time of the experimental animals.
D000667:Ampicillin / Q000008:administration & dosage; D000681:Amylases / Q000008:administration & dosage; D000818:Animals; D004338:Drug Combinations / Q000008:administration & dosage; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D004800:Enzymes, Immobilized / Q000008:administration & dosage*; D007273:Injections, Intramuscular; D010447:Peptide Hydrolases / Q000008:administration & dosage*; D010538:Peritonitis / Q000188:drug therapy*; D011817:Rabbits; D013997:Time Factors
D004338:Drug Combinations; D004800:Enzymes, Immobilized; C009402:amylase, phosphates, proteases drug combinations; D000667:Ampicillin; D000681:Amylases; D010447:Peptide Hydrolases
Parenteral'noe primenenie "immobilizovannoĭ" mikrobnoĭ proteazy v kompleksnom lechenii ékpserimental'nogo peritonita.