title: [Combination treatment of atrial arrhythmias with quinidine-verapamil].
abstract: Between 1977 and 1979, a combined antiarrhythmic therapy with Quinidine and Verapamil was used to treat 66 patients (aged 16 to 69 years) with chronic atrial arrhythmias of different etiology. In 60% of the 43 cases with atrial fibrillation the combined therapy was effective in reversing atrial fibrillation to regular sinus rhythm. The frequency of successful responses to Quinidine - Verapamil amounted to more than twice compared with earlier therapeutic results with Quinidine only. In 65% of the 23 cases with atrial extrasystoles or atrial tachycardias a significant reduction of the ectopics could be achieved or a regular sinus rhythm could be established. Thus, the combined therapy with Quinidine - Verapamil is very effective in abolishing chronic atrial arrhythmias, especially atrial fibrillation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy; D005117:Cardiac Complexes, Premature / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006325:Heart Atria / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000008:administration & dosage* / Q000627:therapeutic use; D013610:Tachycardia / Q000188:drug therapy; D014700:Verapamil / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D014700:Verapamil; D011802:Quinidine
vernacular_title: Kombinierte Behandlung chronische Vorhof-Rhythmusstörungen mit Chinidin-Verapamil.