Incidence of gamma-globulin banding in a healthy population by high-resolution electrophoresis.
We report the incidence of electrophoretically homogeneous protein bands occurring in the gamma-globulin region in serum samples from 600 healthy adults, as determined with a high-resolution electrophoretic system. One or more electrophoretically homogeneous protein bands of various intensities were detected in the gamma-globulin region of 30 specimens when we used an improved agarose electrophoretic system, and in two specimens when we used a cellulose acetate electrophoretic system. Improvement of the agarose gel electrophoretic system thus enhanced its sensitivity in defining homogeneous protein bands in the gamma-globulin region. The incidence of these bands in a healthy population is approximately 5%.
D000328:Adult; D004587:Electrophoresis, Agar Gel; D004588:Electrophoresis, Cellulose Acetate; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005719:gamma-Globulins / Q000032:analysis*
D005719:gamma-Globulins