title: Leukocyte and fibroblast interferon genes are located on human chromosome 9.
abstract: At least eight leukocyte interferon genes (IFL) and the single fibroblast interferon gene (IFF) have been located on chromosome 9 in humans. In somatic cell hybrids of human and mouse cells containing a normal complement of mouse parental cell chromosomes but reduced numbers of human chromosomes, the human leukocyte and fibroblast interferon DNA sequences were present only when human chromosome 9 was also present.
mesh_terms: D000818:Animals; D002460:Cell Line; D002877:Chromosomes, Human / Q000378:metabolism; D002906:Chromosomes, Human, 6-12 and X / Q000378:metabolism*; D002999:Clone Cells / Q000378:metabolism; D004262:DNA Restriction Enzymes; D005347:Fibroblasts / Q000378:metabolism*; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000378:metabolism; D007372:Interferons / Q000235:genetics*; D007962:Leukocytes / Q000378:metabolism*; D051379:Mice; D009693:Nucleic Acid Hybridization
chemical_list: D007372:Interferons; D004262:DNA Restriction Enzymes