title: The relationship of myelin basic protein (arginine) methyltransferase to myelination in mouse spinal cord.
abstract: The relationship between the activity of myelin basic protein (arginine) methyltransferase and myelination in the mouse spinal cord has been examined. The activity of this methylase increases between 8 and 45 days postnatal age and correlates well with other parameters of myelination. A comparison of myelin basic protein methylase with histone methylase activity during development indicates that each is a distinct, specific enzyme activity. Together, these results are considered to establish myelin based protein methylase as a myelination-related enzyme.
mesh_terms: D000375:Aging; D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; D006657:Histones / Q000378:metabolism; D007700:Kinetics; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism; D051379:Mice; D004676:Myelin Basic Protein / Q000378:metabolism; D009186:Myelin Sheath / Q000378:metabolism*; D011496:Protein Methyltransferases / Q000378:metabolism*; D011484:Protein-Arginine N-Methyltransferases / Q000378:metabolism*; D013116:Spinal Cord / Q000201:enzymology* / Q000254:growth & development
chemical_list: D006657:Histones; D004676:Myelin Basic Protein; D000076983:Histone Methyltransferases; D008780:Methyltransferases; D011496:Protein Methyltransferases; D011484:Protein-Arginine N-Methyltransferases; D011495:Histone-Lysine N-Methyltransferase