Donor toxicity in granulocyte collections: association of lichen planus with the use of hydroxyethyl starch leukapheresis.
A normal male volunteer developed lichen planus in association with leukapheresis, with HES used to increase granulocyte yield. Although there is no direct proof of a causative relationship, the temporal association of the onset of initial symptoms and HES infusion strongly supports such a conclusion.
D000328:Adult; D001803:Blood Transfusion; D006098:Granulocytes / Q000637:transplantation*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000009:adverse effects*; D007937:Leukapheresis; D008010:Lichen Planus / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D013213:Starch / Q000031:analogs & derivatives*
D006895:Hydroxyethyl Starch Derivatives; D013213:Starch