title: [Effect of drugs on the permeability of the histohematic barriers in a complicated course of myocardial infarct].
abstract: The investigations have shown the pathogenetic role of enhanced capillary permeability on the development of myocardial infarction and its complications. To a definite degree the above disorders are conditioned by the activation of the kallikrein-kinin system. This made us try contrykal with heparin in the comprehensive system of treatment of these patients. A clear-cut clinical and laboratory effect has been obtained which justifies recommending the use of protease inhibitors in complicated myocardial infarction.
mesh_terms: D000328:Adult; D000368:Aged; D007611:Aprotinin / Q000627:therapeutic use; D002199:Capillary Permeability / Q000187:drug effects*; D004359:Drug Therapy, Combination; D004418:Dyspnea, Paroxysmal / Q000188:drug therapy; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000188:drug therapy; D011654:Pulmonary Edema / Q000188:drug therapy; D012770:Shock, Cardiogenic / Q000188:drug therapy; D013997:Time Factors
chemical_list: D006493:Heparin; D007611:Aprotinin
vernacular_title: Medikamentoznoe vozdeĭstvie na pronitsaemost' gistogematicheskikh bar'erov pri oslozhnennom techenii infarkta miokarda.