[Cytochemical study of the RNA in rat adenohypophysis cells during mammary carcinogenesis induced by 7-12-dimethyl-(a)-benzanthracene (DMBA)].
A cytochemical study of RNA was carried out in gonadotropic basophils and oxyphils of adenohypophysis of albino nonstrain rats during DMBA-induced mammary cancer growth. A stage character is found for changes in the RNA content depending on the mammary carcinogenesis phase. This shows that DMBA carcinogenic action besides a direct damage effect on the mammary gland is realized to a considerable extent through the endocrine system.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology*; D000818:Animals; D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D005260:Female; D006651:Histocytochemistry; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000378:metabolism*; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D001551:Benz(a)Anthracenes; D015127:9,10-Dimethyl-1,2-benzanthracene; D012313:RNA
Tsitokhimicheskoe izuchenie RNK v kletkakh adenogipofiza krys v protsesse razvitiia raka molochnoĭ zhelezy, indutsirovannogo 7-12-dimetil-(a)benzantratsenom (DMBA).