title: Promoter sequence for stringent control of bacterial ribonucleic acid synthesis.
abstract: In bacterial promoters subject to stringent control the heptanucleotide sequence spanning nucleotide positions -5 to +2 (defining the -10 region [D. Pribnow, J. Mol. Biol. 99:419-443, 1975] as positions -12 to -6) is highly conserved. This conserved region, for which the best consensus sequence is [Formula: see text] is absent from promoters which are not under stringent control.
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D009154:Mutation; D009711:Nucleotides / Q000032:analysis; D009876:Operon; D012329:RNA, Bacterial / Q000096:biosynthesis / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D009711:Nucleotides; D012329:RNA, Bacterial