[Cytological characteristics of erythropoiesis in thalassemia. I. Functional characteristics of the nucleated elements of erythropoiesis in the bone marrow].
In 24 patients affected with thalassaemia of various degrees of seriousness the functional condition of nuclear cells or red serie was investigated in the bone-marrow. The investigation was carried out by analyzing partial erythroblastogrammes, evaluating proliferative activity according to the 3H-thymidine marking index and determining ineffective erythropoiesis by means of nucleated PAS-positive erythroblasts. The findings reveal the degree of seriousness of the disease being directly dependent on the extent of functional disturbances in the cells of the erythropoietic system.
D001854:Bone Marrow Cells; D001856:Bone Marrow Examination; D004900:Erythroblasts; D004920:Erythropoiesis; D006801:Humans; D011134:Polysaccharides / Q000097:blood; D013789:Thalassemia / Q000097:blood*
D011134:Polysaccharides
Zytologische Besonderheiten der Erythropoese bei der Thalassämie. Teil I: Funktionelle Charakteristik der kernhaltigen Elemente der Erythropoese im Knochenmark.