Antiviral effects of interferon on a somatic cell hybrid between two Burkitt's lymphoma cell lines of different interferon sensitivities.
A somatic cell hybrid between two human Burkitt's lymphoma cell lines, Raji and Daudi, was infected with either Epstein-Barr virus or vesicular stomatitis virus after interferon treatment. Raji cells are resistant to the antiviral effects of exogenously added interferon, whereas Daudi cells are interferon sensitive. The Raji-Daudi hybrid showed an interferon sensitivity that was intermediary to that of the parental cells against both viruses.
D002051:Burkitt Lymphoma; D002460:Cell Line; D004854:Herpesvirus 4, Human / Q000254:growth & development*; D006801:Humans; D006822:Hybrid Cells / Q000382:microbiology*; D007372:Interferons / Q000494:pharmacology*; D014721:Vesicular stomatitis Indiana virus / Q000254:growth & development*
D007372:Interferons