title: A thiol-ester in alpha 2-macroglobulin cleaved during proteinase complex formation.
mesh_terms: D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D010196:Pancreatic Elastase / Q000378:metabolism; D011489:Protein Denaturation; D013438:Sulfhydryl Compounds; D014357:Trypsin / Q000378:metabolism; D000511:alpha-Macroglobulins / Q000378:metabolism*
chemical_list: D013438:Sulfhydryl Compounds; D000511:alpha-Macroglobulins; D010450:Endopeptidases; D010196:Pancreatic Elastase; D014357:Trypsin