title: [Local fibrinolytic therapy with terrilytin in coagulated hemothorax and pleural empyema].
abstract: On the basis of experimental and laboratory investigations high fibrinolytic effect of the home proteolytic enzyme terrilythin and the absence of general toxic reactions after intrapleural administration of the drug have been proved. The article describes results of clinical results of clinical tests of the effectiveness of terrilythin in coagulated hemothorax after traumas of the chest and operations on the lungs and in 55 patients with acute pro-fibrinous pleurisy. The successful preventive sanitation was performed in 43 of 50 patients with coagulated hemothorax and initial symptoms of the infectious process as well at the development of pleural empyema were averted.
mesh_terms: D000287:Administration, Topical; D000681:Amylases / Q000627:therapeutic use*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004338:Drug Combinations / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004653:Empyema / Q000628:therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006491:Hemothorax / Q000628:therapy*; D006801:Humans; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D011013:Pneumonectomy; D011817:Rabbits
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D005343:Fibrinolytic Agents; C009402:amylase, phosphates, proteases drug combinations; D000681:Amylases; D010447:Peptide Hydrolases
vernacular_title: Mestnaia fibrinoliticheskaia terapiia terrilitinom pri svernuvshemsia gemotorakse i émpieme plevry.