[Unusual course in 2 patients with testicular teratoma during vinblastine-cyclophosphamide chemotherapy].
Two patients with metastatic embryonal testicular cancer achieved complete remission receiving a vinblastine-cyclophosphamide combination chemotherapy. After a previous treatment with vinblastine-bleomycin one patient had developed progressive disease, the other one had attained partial remission only. Because of our own experiences and because of the results in single agent chemotherapy this well tolerated vinblastine-cyclophosphamide combination is proposed as maintenance therapy for testicular teratoma. Other maintenance therapies according to the literature and the problem of maintenance therapy in general are discussed.
D000328:Adult; D001761:Bleomycin / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D011879:Radiotherapy Dosage; D013724:Teratoma / Q000188:drug therapy* / Q000556:secondary; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000556:secondary; D014747:Vinblastine / Q000627:therapeutic use*
D001761:Bleomycin; D014747:Vinblastine; D003520:Cyclophosphamide
Ungewöhnlicher Verlauf bei zwei Patienten mit Hoden-Teratom unter Vinblastin-Cyclophosphamid-Chemotherapie.