[The effect of positive pressure breathing on the correlation between pulmonary wedge and left atrial pressure in hyper-, normo- and hypovolaemic dogs (author's transl)].
The effect of altering end-expiratory inflation pressure from 0 to 20 cm H2O in relation to the pulmonary capillary wedge-pressure (PCWP) and the left atrial pressure (LAP) were studied in dogs, whose blood volume was varied by infusion of dextran or by haemorrhage. In the hyper- and normovolaemic state there was a good correlation between PCWP and LAP up to an end-expiratory pressure of 15 cm H2O. In the hypovolaemic dogs this close agreement existed only up to levels of PEEP 10 cm H2O. Above this end-expiratory pressure pulmonary capillary wedge-pressure increased more than left atrial pressure.
D000818:Animals; D001794:Blood Pressure; D001810:Blood Volume; D001815:Bloodletting; D003911:Dextrans; D003971:Diastole; D004285:Dogs; D005260:Female; D006325:Heart Atria; D006863:Hydrogen-Ion Concentration; D008297:Male; D010313:Partial Pressure; D011175:Positive-Pressure Respiration; D013599:Systole
D003911:Dextrans
Tierexperimentelle Untersuchungen über den Einfluss des endexspiratorischen Druckes auf die Beziehung zwischen linkem Vorhofdruck und pulmonal-arteriellem Wedge-Druck in Abhängigkeit vom Füllungszustand des Gefässsystems.