title: [Debrisorb therapy of severe hand infections].
abstract: Treatment with DEBRISORB, a new topical agent formed by three dimensional network of dextran polymers in porous hydrophilic beads, was used in 26 cases of infected wounds in the hand. These were of traumatic and postoperative origin, often with remaining necrotic areas and in a few cases with a considerable oedema. The special effect of DEBRISORB was in absorbing the exudate and in reducing the inflammation and swelling of the discharging wounds. Within a few days secretion was diminished and healthy granulation tissue appeared. For covering the defects we employed local transposition flaps, direct flaps and split-skin grafts without complications. Local treatment with DEBRISORB is an effective method to clean infected wounds, to reduce inflammation and oedema, and is useful as treatment before grafting.
mesh_terms: D000287:Administration, Topical; D003911:Dextrans / Q000627:therapeutic use*; D006230:Hand Injuries / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D013530:Surgical Wound Infection / Q000188:drug therapy; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000188:drug therapy*
chemical_list: D003911:Dextrans; C013471:dextranomer
vernacular_title: DEBRISORB-Behandlung bei schweren Infektionen im Bereich der Hand.