title: Exercise-induced urinary abnormalities in long-distance runners.
abstract: The post-exercise urine samples from 122 long-distance runners showed evident abnormalities upon microscopic examination in 95% of all subjects. Proteinuria, alone or with microscopic hematuria, was frequently found. Macroscopic hematuria was a rare occurrence. The urine samples collected in 30 runners before, immediately after the race, and 6, 12, 24, 36, and 48 h later showed a significant post-race decrease in the osmolarity and a significant increase in gamma-glutamyl transferase and N-acetyl-beta-glucosaminidase enzyme activity. Plasma renin activity and plasma aldosterone, determined before and after the race in nine runners, showed a significant increase in the post-race samples. The abnormal urinary findings disappeared in all cases within 24-36 h. It can be concluded that urinary abnormalities are very common after exercise. These abnormalities are most often of a "renal" origin, probably due to a temporary hemodynamic impairment, partially of glomerular but principally of tubular function.
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine; D000293:Adolescent; D000328:Adult; D000450:Aldosterone / Q000652:urine; D004573:Electrolytes / Q000652:urine; D005260:Female; D006029:Glycosuria / Q000652:urine; D006417:Hematuria / Q000652:urine*; D006801:Humans; D008875:Middle Aged; D010807:Physical Endurance; D011507:Proteinuria / Q000652:urine*; D012083:Renin / Q000652:urine; D012420:Running; D005723:gamma-Glutamyltransferase / Q000652:urine
chemical_list: D004573:Electrolytes; D000450:Aldosterone; D005723:gamma-Glutamyltransferase; D000118:Acetylglucosaminidase; D012083:Renin