Juvenile rheumatoid arthritis in two siblings: co-existence with polyarteritis nodosa in one parent.
Two siblings with identical HLA profiles developed the clinical picture of Juvenile Rheumatoid Arthritis of the pauciarticular variety with iritis. One parent had Polyarteritis Nodosa while both parents and siblings demonstrated the B15 DR5 antigens.
D000328:Adult; D001171:Arthritis, Juvenile / Q000150:complications / Q000235:genetics* / Q000276:immunology; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D015805:HLA-DR5 Antigen; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000235:genetics* / Q000276:immunology; D014605:Uveitis / Q000150:complications
D006680:HLA Antigens; D015805:HLA-DR5 Antigen; D000949:Histocompatibility Antigens Class II