The radioimmunoassay of a carcinoembryonic antigen fraction.
A qualitative and clinical evaluation of a radioimmunoassay for a carcinoembryonic antigen (CEA) fraction in serum is presented. The technique shows cross-reactions with normal organs' extracts lower than 0.05% and a 0.9977 correlation coefficient. The coefficients of variation indicate satisfactory precision. In the clinical study it was found that sensitivity for lung cancer was higher than for colorectal cancer. Specificity for cancer was 98.3%. These results suggest that the CEA fraction employed shows more lung cancer determinants than for digestive cancer.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D003110:Colonic Neoplasms / Q000032:analysis*; D003429:Cross Reactions; D000939:Epitopes; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012004:Rectal Neoplasms / Q000032:analysis*
D002272:Carcinoembryonic Antigen; D000939:Epitopes