Warfarin-sulfinpyrazone interaction on binding to human serum albumin.
Sulfinpyrazone displacement of warfarin from human serum albumin was studied in-vitro. At low sulfinpyrazone concentrations one molecule of warfarin is displaced on binding by one molecule of sulfinpyrazone. Clinical plasma concentrations of sulfinpyrazone are, however, too low to cause significant displacement.
D001667:Binding, Competitive; D006801:Humans; D066298:In Vitro Techniques; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism*; D013442:Sulfinpyrazone / Q000097:blood*; D014859:Warfarin / Q000097:blood*
D012709:Serum Albumin; D014859:Warfarin; D013442:Sulfinpyrazone