title: The value of exogenous interferon in adenovirus keratoconjunctivitis. Preliminary results.
abstract: Fourteen patients with confirmed adenovirus (kerato-) conjunctivitis were treated at random with either exogenous interferon alpha (Le) (3 x 10(6) IU/ml, 1 drop daily) or with albumin. We observed no clinically relevant therapeutic effects. However, interferon seemed to exert a prophylactic effect on uninflamed fellow eyes. The prophylactic potency of interferon in adenovirus (kerato-)conjunctivitis should be evaluated in further controlled trials.
mesh_terms: D000257:Adenoviridae Infections / Q000188:drug therapy*; D000258:Adenovirus Infections, Human / Q000188:drug therapy* / Q000517:prevention & control; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D007637:Keratoconjunctivitis / Q000628:therapy*; D011897:Random Allocation
chemical_list: D007372:Interferons