Fimbrial antigens of Escherichia coli 01:K1:H7 and 01:K1:H- strains isolated from patients with urinary tract infections.
Thirty E. coli strains belonging to serotypes 01:K1:H7 and 01:K1:H- were examined for the presence of fimbrial (F) antigens by crossed immunoelectrophoresis. All strains exhibited a mannose-resistant haemagglutination of human and monkey erythrocytes. This ability was found to be highly correlated with the existence of F antigens. Another correlation was found between O:K:H serotype and F antigen. Eleven 01:K1:H7 strains were associated with fimbrial antigen F11 which was also demonstrated in five immotile variants of this serotype. In other fourteen strains of serotype 01:K1:H-, however, the F9 antigen could be detected. The F9 and F11 antigens belong to the group of P fimbriae. The 01:K1:H7:F11 and 01:K1:H-:F9 isolates were supposed to be of different clonal origin.
D000328:Adult; D000368:Aged; D000372:Agglutination Tests; D000942:Antigens, Bacterial / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D003378:Counterimmunoelectrophoresis; D004926:Escherichia coli / Q000145:classification / Q000276:immunology*; D005260:Female; D010861:Fimbriae, Bacterial / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D008875:Middle Aged; D011704:Pyelonephritis / Q000382:microbiology; D012703:Serotyping; D014552:Urinary Tract Infections / Q000382:microbiology*
D000942:Antigens, Bacterial