Influence of ischemia on retrograde axonal transport in the posterior column fibers of the dog.
The retrograde axonal transport rate in the posterior spinal root was studied by means of the horseradish peroxidase injection in the control dogs and the dogs with the ischemia induced by the lumbal aorta ligature. As the results show, the increase in the retrograde axonal transport rate after 4 h ischemia occured from 141 +/- 6 mm/24 h to 270 +/- 31 mm/24 h. The retrograde transport rate after 7 d ischemia being 137 +/- 7 mm/24h reaches approximately the control values.
D000818:Animals; D001370:Axonal Transport; D004285:Dogs; D005260:Female; D005727:Ganglia, Spinal / Q000378:metabolism; D007511:Ischemia / Q000378:metabolism*; D008297:Male; D010544:Peroxidases / Q000378:metabolism; D013116:Spinal Cord / Q000098:blood supply*; D013126:Spinal Nerve Roots / Q000378:metabolism
D010544:Peroxidases