Macrophages in prostatic fluid.
Non-specific esterase staining has been found useful in the detection of macrophages in prostatic fluid (PF). In the early stage of acute prostatitis most of the leucocytes in a smear of PF took up the stain, suggesting the dominant participation of macrophages in the inflammatory area in this stage of the disease. In chronic prostatitis, only a few leucocytes took up the stain. In female acute cystitis, none of the large numbers of leucocytes exhibited staining at any stage of the disease. The reason for this is still to be determined. Frozen sections of prostatic tissue from patients with chronic prostatitis revealed similar cells around the acini and these appeared to be the source of the macrophages which appeared in the PF.
D001826:Body Fluids / Q000166:cytology; D003556:Cystitis / Q000473:pathology; D005260:Female; D006801:Humans; D008264:Macrophages / Q000473:pathology*; D008297:Male; D011467:Prostate / Q000378:metabolism; D011470:Prostatic Hyperplasia / Q000473:pathology; D011472:Prostatitis / Q000473:pathology*; D013194:Staining and Labeling; D014556:Urine / Q000166:cytology