title: Antichlamydial antibodies in chronic palmoplantar pustulosis.
abstract: Serum antichlamydial antibodies were determined with an immunofluorescence method in 40 patients affected by palmoplantar pustulosis (PPP). Antibody titre greater than or equal to 16 was found in 53% of the cases, the titre being greater than or equal to 64 in 38% of the patients. By comparison, a titre of greater than or equal to 64 was found in 13% out of 55 psoriatics, in 12% out of 41 eczema and urticaria patients, and in 3% out of 37 healthy controls. The difference between the results from the PPP patients and that of the healthy controls was statistically significant (p < 0.01). In only 8 of the 40 PPP patients was any additional evidence found of a previous venereal infection. The possibility that PPP may represent an abnormal reaction to infectious agents, e.g. Chlamydia, is discussed.
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D002689:Chlamydia / Q000276:immunology*; D002908:Chronic Disease; D005260:Female; D005455:Fluorescent Antibody Technique; D005533:Foot Dermatoses / Q000276:immunology / Q000382:microbiology; D006229:Hand Dermatoses / Q000276:immunology / Q000382:microbiology; D006801:Humans; D008297:Male; D011711:Pyoderma / Q000276:immunology* / Q000382:microbiology; D012749:Sexually Transmitted Diseases / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial