[Effect of lithium preparations on cardiac arrhythmias resulting from ligation of the common carotid arteries].
In experiments on cats with dissected vagus and aortal nerves under chloralose-urethane anesthesia, ventricular disorders of the cardiac rhythm were induced by ligation of the common carotid arteries. Appearance of arrhythmias was preceded by an increase in the sympathetic activity (recorded from the inferior cardiac or renal nerve) accompanied by a rise of the arterial blood pressure and of the heart rate. Intravenous injection of lithium chloride or hydroxybutyrate resulted in lowering of the sympathetic activity, arterial blood pressure, and heart rate, and led to the recovery of the sinus rhythm.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000209:etiology; D001794:Blood Pressure; D005117:Cardiac Complexes, Premature / Q000188:drug therapy; D002340:Carotid Artery Diseases / Q000150:complications*; D002415:Cats; D002712:Chlorides / Q000627:therapeutic use; D006339:Heart Rate; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D008094:Lithium / Q000627:therapeutic use*; D018021:Lithium Chloride; D009942:Organometallic Compounds; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013610:Tachycardia / Q000188:drug therapy
D002712:Chlorides; D006885:Hydroxybutyrates; D009942:Organometallic Compounds; C022826:lithium hydroxybutyrate; D008094:Lithium; D018021:Lithium Chloride
Vliianie preparatov litiia na serdechnye aritmii, vyzvannye perezhatiem obshchikh sonnykh arteriĭ.