title: Radial chorioretinal folds. A sign of choroidal neovascularization.
abstract: A radial pattern of chorioretinal folds surrounding the margins of a localized macular detachment occurred in four patients with drusen of Bruch's membrane. Biomicroscopic and angiographic findings suggested that contraction of a subpigment epithelial choroidal neovascular membrane caused a focal area of shrinkage, or puckering, of the choroid and a series of chorioretinal folds radiating outward from the edge of the membrane. In two eyes, these radial folds developed early in the course of the macular detachment before any other reliable biomicroscopic signs of choroidal neovascularization were present.
mesh_terms: D000368:Aged; D002829:Choroid / Q000098:blood supply*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009389:Neovascularization, Pathologic; D012163:Retinal Detachment / Q000473:pathology*; D014603:Uveal Diseases / Q000473:pathology