title: Synthesis of potential anticonvulsants: condensation of isatins with acetone and related ketones.
abstract: Substituted isatins were condensed with acetone and other ketones to give analogs of 3-hydroxy-3-acetonyloxindole. Some of these alcohols were dehydrated. Several compounds with anticonvulsant activity were obtained.
mesh_terms: D000096:Acetone; D000927:Anticonvulsants / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D004353:Drug Evaluation, Preclinical; D006897:Hydroxyindoleacetic Acid / Q000031:analogs & derivatives; D007211:Indoles; D007510:Isatin
chemical_list: D000927:Anticonvulsants; D007211:Indoles; D000096:Acetone; D006897:Hydroxyindoleacetic Acid; D007510:Isatin