[Determination of the level of plasma beta-thromboglobulin in diabetes].
Plasma beta-TG was measured radioimmunoassay on 23 controls and 84 diabetics. The diabetic patients were divided in three groups: I. Patients without complications, insulin-dependants or not. II. Patients with retinopathy, without severe complications. III. Patients with retinopathy and distal arteritis. beta-TG level in control group is 23,4 +/- 7,6 ng/ml and is comparable with literature. An important increase of beta-TG average level was observed for the three diabetic groups. The almost equal increase between groups I and II could be explained by a comparable hyperagregability, as previously described in diabetes. There could be an increase of hyperagregability with arteritis appearance, and a increase of beta-TG release. Correlation between these two parameters remains to be demonstrated.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001167:Arteritis / Q000097:blood; D001609:Beta-Globulins / Q000032:analysis*; D001792:Blood Platelets / Q000502:physiology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood*; D003925:Diabetic Angiopathies / Q000097:blood; D003930:Diabetic Retinopathy / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D011863:Radioimmunoassay; D001620:beta-Thromboglobulin / Q000032:analysis*
D001609:Beta-Globulins; D001620:beta-Thromboglobulin
Détermination du taux de bêta-thromboglobuline plasmatique au cours de la maladie diabétique.