title: [Radioimmunological study of the hemagglutinin of influenza viruses subtype H1N1].
abstract: Radioimmunoassay were carried out with influenza A/Cambridge/46, A/FM/1/47, A/England/1/51, A/Denwer/1/57, and A/USSR/90/79 of the H1N1 subtype to determine the antigenic determinants of influenza A/USSR/90/77 virus hemagglutinin. The test system included 125I-labeled hemagglutinin of A/USSR/90/77 virus and homologous antiserum to this virus. The most marked antigenic similarity was found between A/USSR/90/77 and A/USSR/90/79 viruses. The A/Cambridge/46 and A/Denwer/1/57 viruses showed clear-cut differences in the antigenic determinants from the A/USSR/90/77 virus.
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D000939:Epitopes / Q000032:analysis; D006389:Hemagglutinins, Viral / Q000032:analysis*; D053118:Influenza A Virus, H1N1 Subtype; D009980:Influenza A virus / Q000276:immunology*; D011863:Radioimmunoassay / Q000379:methods*
chemical_list: D000956:Antigens, Viral; D000939:Epitopes; D006389:Hemagglutinins, Viral
vernacular_title: Radioimmunologichekoe izuchenie gemaggliutinina virusov grippa podtipa H1N1.