The immunoperoxidase technique a review of its application to diseases of the female genital tract.
Immunoperoxidase techniques (IMPO) have gained widespread acceptance by virtue of their potential use in the fields of pathologic diagnosis and research. The increasing availability of specific antisera have enabled investigators to localize a variety of hormones, enzymes, oncofetal antigens, viral antigens, micro-organisms, and other biologic markers. IMPO techniques have been employed extensively in the investigation of gynecologic diseases and have been useful, not only as special stains identifying specific neoplasms, but also for providing addtional insight into the biologic behavior of gynecologic neoplasms, and the functional and pathogaenetic nature of germ cell tumors, gonadal stromal neoplasms, and peptide hormone-producing neoplasms. Recent studies using IMPO to localize hormone receptors and viral antigens promise the continued use of this technique as a research tool to complement the more complex methods currently in use.
D000951:Antigens, Neoplasm / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000378:metabolism; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis*; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D000509:alpha-Fetoproteins / Q000378:metabolism
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D012739:Gonadal Steroid Hormones; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D000509:alpha-Fetoproteins