Prevention of reformation of pelvic adhesions by "Barrier" methods.
Twenty-five female rabbits received symmetrical injuries on both uterine horns. Ten days later the animals were re-operated and the adhesions were lysed and covered on one of the uterine horns with silicone in ten animals (Group A) and with Surgical in ten other animals (Group B). The contralateral uterine horns served as internal controls and five animals in whom no barrier was used served as an external control (Group C). The silicone was removed in a third operation ten days later. A scoring method was used for the quantitation of the adhesions. The reformation of adhesions on the treated side was reduced in Group A (mean score 1.4 +/- 1.5) and increased in Group B (mean score 3.8 +/- 0.43) in comparison with Group C (mean score 2.5 +/- 1.03) (P less than 0.02).
D000818:Animals; D002482:Cellulose / Q000031:analogs & derivatives*; D002483:Cellulose, Oxidized / Q000627:therapeutic use*; D005260:Female; D007247:Infertility, Female / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D011817:Rabbits; D012826:Silicone Elastomers / Q000627:therapeutic use*; D000267:Tissue Adhesions / Q000517:prevention & control; D014591:Uterine Diseases / Q000517:prevention & control*
D002483:Cellulose, Oxidized; D012826:Silicone Elastomers; C013695:Surgicel; D002482:Cellulose