The treatment of head and neck carcinoma with adriamycin and bleomycin using adjuvant hyperthermia.
Twenty-two cases of carcinoma of the head and neck (predominantly squamous), in a variety of sites, were treated with an oncolytic regime of Adriamycin and Bleomycin. Adjuvant hyperthermia was given to all cases; differing techniques of drug administration were used, depending on whether a case had received previous irradiation. Twenty-one cases showed response to treatment. Post-irradiation cases fared less well than those in which radiotherapy was synchronised with treatment.
D000368:Aged; D001761:Bleomycin / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000628:therapy*; D004317:Doxorubicin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000628:therapy*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011867:Radioisotope Teletherapy
D001761:Bleomycin; D004317:Doxorubicin