Total serum IgE influence on the anaphylactic and 48/80 induced histamine release from isolated rat mast cells.
We have investigated the influence of non-specific IgE on histamine release induced by antigen or compound 48/80. Our results indicate that increased amounts of IgE influence antigen mediated histamine release as well as release induced by a non-immunological stimulus like compound 48/80.
D000707:Anaphylaxis / Q000378:metabolism*; D000818:Animals; D006636:Histamine Release / Q000187:drug effects; D007073:Immunoglobulin E / Q000502:physiology*; D066298:In Vitro Techniques; D008407:Mast Cells / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D003189:p-Methoxy-N-methylphenethylamine / Q000494:pharmacology*
D007073:Immunoglobulin E; D003189:p-Methoxy-N-methylphenethylamine