[Fluid storage of thrombocytes. Reaction of stored blood platelets from ACD-AG blood to hypotonic shock].
During liquid storage of platelet concentrates (PC) at 277 K (4 degrees C) and 295 K (22 degrees C) prepared from ACD-AG-blood the cells lost their ability to hypotonic shock response (HSR) within 3 days. The HSR maintained on the initial level during 3 days in platelets as platelet rich plasma (PRP) at 295 K, but fell significantly at 277 K. The number of platelets decreased more rapidly at room temperature than at 277 degrees K, but a statistical difference did not exist. At room temperature the pH-fall was accelerated and came to 6.5 even after 1 day storage of PC but only after roughly 5 days in PRP.
D000143:Acids; D001792:Blood Platelets; D001793:Blood Preservation; D002470:Cell Survival; D002951:Citrates; D003911:Dextrans; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007038:Hypotonic Solutions / Q000494:pharmacology*
D000143:Acids; D002951:Citrates; D003911:Dextrans; D007038:Hypotonic Solutions
Zur thrombozytenflüssiglagerung. Reaktion gelagerter Blutplättchen aus ACD-AG-Blut auf hypotonen Schock.