5-OH-Tryptophane in migraine: clinical and neurophysiological considerations.
The clinical effects of the protracted treatment with 5-OH Tryptophane (5-HTP) of some patients with chronic migraine are compared with other patients with acetylsalicylic acid. The pain threshold was neurophysiologically determined in migraneous on patients whose response to 5-HTP therapy was specially good. The results with 5-HTP can be accounted for by an action of the substance on the serotonin turnover with activation of the serotoninergic antinociceptive system.
D006916:5-Hydroxytryptophan / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D009619:Nociceptors / Q000187:drug effects
D006916:5-Hydroxytryptophan; D001241:Aspirin