Studies on circulating immune complexes of the liver disease. 4. Clq binding activity.
Serum Clq binding activity (ClqBA) is increased in diabetes mellitus with liver injury, carcinoma of gastrointestinal tract with metastatic liver and chronic liver disease (CLD). Significant elevations of ClqBA level are observed in the order of liver cirrhosis, chronic aggressive hepatitis and chronic persistent hepatitis. In CLD there are significant correlations between ClqBA and gamma-globulin, rheumatoid factor, anti-DNA-antibody, CH50, C3, C4, C3-activator and HBsAg.
D000974:Antibodies, Antinuclear / Q000032:analysis; D000936:Antigen-Antibody Complex; D002908:Chronic Disease; D003172:Complement C1 / Q000276:immunology* / Q000302:isolation & purification; D004247:DNA / Q000276:immunology; D048909:Diabetes Complications; D006505:Hepatitis / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008103:Liver Cirrhosis / Q000276:immunology; D008107:Liver Diseases / Q000276:immunology*; D008113:Liver Neoplasms / Q000276:immunology / Q000556:secondary; D012217:Rheumatoid Factor / Q000032:analysis; D005719:gamma-Globulins / Q000276:immunology
D000974:Antibodies, Antinuclear; D000936:Antigen-Antibody Complex; D003172:Complement C1; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D005719:gamma-Globulins; D004247:DNA; D012217:Rheumatoid Factor