Monoclonal antibodies which recognize different cell types in the rat retina.
Seven monoclonal antibodies have been produced against a membrane preparation from adult rat retina. Three antibodies reacted with particular regions of rat photoreceptor cell surfaces: RET-P1 labelled the cell bodies, outer and inner segments (rods but not cones), RET-P2 labelled only outer segments and RET-P3 labelled only the cell bodies. Three antibodies reacted with glial cells; RET-G2 and RET-G3 were specific for Müller cells, RET-G1 also labelled glia elsewhere in brain. The seventh antibody (RET-N1) reacted with many types of neuronal cells.
D000818:Animals; D000906:Antibodies; D000918:Antibody Specificity; D002999:Clone Cells / Q000276:immunology; D000939:Epitopes; D005455:Fluorescent Antibody Technique; D007158:Immunologic Techniques; D009457:Neuroglia / Q000276:immunology; D009474:Neurons / Q000276:immunology; D010786:Photoreceptor Cells / Q000276:immunology; D051381:Rats; D012160:Retina / Q000166:cytology* / Q000276:immunology; D014018:Tissue Distribution
D000906:Antibodies; D000939:Epitopes