title: Moldy sweetclover poisoning in cattle.
abstract: Some selected clinical and laboratory aspects of moldy sweetclover poisoning in cattle are reviewed. The prothrombin time is preferred when the disease is suspected. The bleeding time and whole blood clotting time test are also used. Dicoumarol is not always detectable in the suspected feed which may be due to sampling technique or inaccuracy in the laboratory assay. The most effective treatment is a whole blood transfusion. Vitamin K(1) (naturally occurring vitamin K) is an effective antidote but too expensive. Vitamin K(3) (synthetic vitamin K) in both the injectable and oral forms are not as effective as K(1) but are used extensively for treatment and prevention. Feeding the suspected feed for two weeks followed by a one week withdrawal successively or by dilution with other feeds will help to reduce the incidence of disease if other feeds are not available. Suspected feed should not be fed to cattle for at least three weeks before surgery or parturition.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000517:prevention & control; D001728:Dicumarol / Q000506:poisoning; D007887:Fabaceae; D005658:Fungi; D010939:Plant Poisoning / Q000175:diagnosis / Q000517:prevention & control / Q000662:veterinary*; D010946:Plants, Medicinal
chemical_list: D001728:Dicumarol