Treatment of contagious caprine pleuropneumonia.
A combination of dihydrostreptomycin sulphate (250 mg/ml) and penicillin G procaine (200,000 iu/ml) was used to treat contagious caprine pleuropneumonia caused by F38 strain of mycoplasma. A single dose of either 20, 30, 40 or 50 mg/kg body weight of the dihydrostreptomycin sulphate led to the recovery of the treated goats. The recovered goats did not transmit CCPP to susceptible goats housed with them for 2 months. The goats which recovered were found to be solidly immune to an in-contact challenge in which all the control goats died of CCPP. The treated and recovered goats were found not to be carriers of the organism.
D000818:Animals; D004096:Dihydrostreptomycin Sulfate / Q000627:therapeutic use; D006041:Goats; D009175:Mycoplasma Infections / Q000662:veterinary*; D010402:Penicillin G Procaine / Q000627:therapeutic use; D011002:Pleuropneumonia, Contagious / Q000188:drug therapy* / Q000401:mortality
D010402:Penicillin G Procaine; D004096:Dihydrostreptomycin Sulfate