The pachyonychia congenita syndrome.
This study presents two patients showing different clinical types of the Pachyonychia congenita Syndrome (PcS). For the first time there is a description of the histopathology of the blister and vesicle formation, as well as of the plantar keratosis. The essential resemblance in the histopathological changes of the different symptoms of the syndrome is discussed.
D000328:Adult; D007644:Darier Disease / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D009264:Nails, Malformed / Q000235:genetics / Q000473:pathology*; D012867:Skin / Q000473:pathology; D013577:Syndrome