Golgi-ANAE positivity in leukemic blast cells: a possible T-suppressor cell leukemia.
Different patterns of acid alpha-naphthyl-acetate esterase (ANAE) positivity in lymphocytes have been related to distinct functional lymphocyte subpopulations. A case of T-ALL with a cytochemical and immunological phenotype consistent with a T-suppressor cell leukemia is reported. In particular a specific pattern of Golgi-ANAE positivity is probably characteristic of TG cells, which include a subset with suppressor function.
D001854:Bone Marrow Cells; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000175:diagnosis*; D008297:Male; D009283:Naphthol AS D Esterase / Q000097:blood*; D013194:Staining and Labeling; D013601:T-Lymphocytes / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000201:enzymology*
D000949:Histocompatibility Antigens Class II; D009283:Naphthol AS D Esterase; D002265:Carboxylic Ester Hydrolases