[Physico-chemical and immunologic properties of the tissue DNA of mice with oncornavirus-induced leukemia].
Active antisera containing antibodies to deproteinized DNA preparations of mouse normal and leukemic tissues have been obtained. Examination of antisera by the quantitative complement fixation test with the corresponding test antigens has demonstrated immunological specificity of DNA preparations isolated from the organs of mice with leukemia induced by oncornaviruses. The DNA specificity in question is inherent not only in the native but also in the thermodenatured molecule of DNA.
D000818:Animals; D003168:Complement Fixation Tests; D004273:DNA, Neoplasm / Q000276:immunology*; D000939:Epitopes / Q000032:analysis; D005622:Friend murine leukemia virus; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D011925:Rauscher Virus; D013154:Spleen
D004273:DNA, Neoplasm; D000939:Epitopes
O fiziko-khimicheskikh i immunologicheskikh svoĭstvakh tkanevoĭ DNK mysheĭ, bol'nykh leĭkozom, indutsirovannym onkornavirusami.