Differential breakdown of phylogenetically diverse ribosomal RNA's inserted via liposomes into mammalian cells.
Liposomes were used to deliver ribosomal RNA's from the different organisms into cultivated mouse plasmacytoma cells. Ribosomal RNA from Escherichia coli was degraded intracellularly within 1 hour, whereas mouse and yeast ribosomal RNA's were degraded more slowly. This indicates that cells can discriminated between different ribosomal RNA's.
D000818:Animals; D002460:Cell Line; D004926:Escherichia coli; D007700:Kinetics; D008081:Liposomes; D051379:Mice; D008970:Molecular Weight; D009374:Neoplasms, Experimental / Q000378:metabolism; D010954:Plasmacytoma / Q000378:metabolism*; D012329:RNA, Bacterial / Q000378:metabolism; D012335:RNA, Ribosomal / Q000378:metabolism*; D012441:Saccharomyces cerevisiae; D013045:Species Specificity
D008081:Liposomes; D012329:RNA, Bacterial; D012335:RNA, Ribosomal