[Effects of lindane upon the reproductive function in four generations running in the quail. Studies of gonads and müllerian tract in embryos, one day chicken and adults (author's transl)].
The effect of lindane commercial solution spraying on quail eggs is studied in four generations running issued from a single parental strain. Observations have been made on fourteen-day embryos, one-day chicken and also two-or eight-month adults quail. The results lead to conclude that pathogenous effects of lindane on gonads and müllerian tract are slowly annuled through successive generations when the experimental procedure consists in treating only the parental eggs. Conversely, following pesticide administration repeated at every generation, the action becomes cumulative and the ratio of aberrations increases. In ovarian and testicular tissues there are cyto-histopathological modifications. Many gonocytes are abnormal and cannot divide. Some of these cells degenerate at the meiotic prophase. Egg production and fertility in adults depend on these phenomenons.
D000818:Animals; D005260:Female; D001556:Hexachlorocyclohexane / Q000494:pharmacology*; D008297:Male; D009865:Oocytes / Q000166:cytology; D010053:Ovary / Q000033:anatomy & histology / Q000187:drug effects*; D010057:Oviducts / Q000033:anatomy & histology / Q000187:drug effects*; D011784:Quail / Q000033:anatomy & histology* / Q000196:embryology / Q000502:physiology; D012098:Reproduction; D013090:Spermatocytes / Q000166:cytology; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects*
D001556:Hexachlorocyclohexane
Effets du lindane sur la fonction reproductrice de quatre générations successives de cailles. Etude des gonades et du tractus müllérien chez l'embryon, le poussin de 1 jour et l'adulte.