[Nucleic acid and protein content of cells of the raphe nuclei of the rat brain when the animals are deprived of the paradoxical sleep phase].
A 24 hours paradoxical sleep deprivation (PSD) with rats resulted in lowering the RNA content in neurons and gliocytes of n. raphé dorsalis by 31 and 18%, resp.; the protein content remaining unchanged. A 48 hours PSD reduced RNA and protein contents in neurons by 31%; in gliocytes both these substances being on the control level. In the neurons of n. raphé pontis, by the end of the 1st day of PSD the contents of both RNA and protein were seen reduced by 16 and 28%, resp.; however, by the end of the 2nd day their levels well compared with those in the control rats. There was a phase oscillation of protein content in gliocytes: from - 19%, on the first day of PSD, to +19%, on the 2nd day. There is a great resemblance in response to PSD between the adrenergic nucleus - locus coeruleus - and n. raphé pontis, whereas their responses differ from that of the serotoninergic n. raphé dorsalis.
D000818:Animals; D001933:Brain Stem / Q000378:metabolism*; D006651:Histocytochemistry; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009457:Neuroglia / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D012313:RNA / Q000378:metabolism*; D011903:Raphe Nuclei / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012892:Sleep Deprivation / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D013997:Time Factors
D009419:Nerve Tissue Proteins; D012313:RNA
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