The molecular basis for the association between HLA-A3 and idiopathic haemochromatosis.
An association was found between idiopathic haemochromatosis and a 6.2-kb Bgl I genomic DNA fragment. This fragment constitutes a class I sequence which correlates with HLA-B3. The Bgl I fragment could represent a sequence in linkage disequilibrium with the haemochromatosis gene.
D015342:DNA Probes; D008040:Genetic Linkage; D005819:Genetic Markers; D015791:HLA-A3 Antigen / Q000235:genetics*; D006432:Hemochromatosis / Q000235:genetics* / Q000276:immunology; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length
D015342:DNA Probes; D005819:Genetic Markers; D015791:HLA-A3 Antigen