[Use of dynamic scintigraphy, x-ray computed tomography, ultrasonic scanning of the kidneys and determination of the enzyme activity and beta 2-microglobulin levels of the blood and urine of arterial hypertension patients].
A total of 59 patients aged 16-74 years with arterial hypertension (AH) were examined. The AH duration was from 0.5 to 28 years. In 42 patients AH was stable, 17 patients had the syndrome of malignant AH. X-ray computerized renal tomography (CRT), dynamic renal scintigraphy (DRS), ultrasonic renal scanning (URS) were used in the study, furthermore, the activities of enzymes (beta-glucuronidase, alanine aminopeptidase, arylsulfatase A), beta 2-microglobulin (beta 2-MG) concentration were determined in the serum and urine. It has been found that combined use of the investigation methods largely increases diagnostic possibilities, significantly expands the data of such invasive procedures as excretory urography, aortography, renal biopsy, and in a number of cases it enables making the diagnosis without applying the invasive procedures. It is advisable to use URS and to determine the enzymatic activity and beta 2-MG concentration in the urine just at the first stage of examining the patients with AH (simultaneously with general clinical methods). When renal pathology is detected or suspected it is necessary to perform DRS. When voluminous process, "mute" kidney, cystic lesions, calculous chronic pyelonephritis are suspected CRT should be employed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000626:Aminopeptidases / Q000097:blood; D001192:Arylsulfatases / Q000097:blood; D018826:CD13 Antigens; D004796:Clinical Enzyme Tests; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis; D005966:Glucuronidase / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000175:diagnosis*; D006974:Hypertension, Malignant / Q000175:diagnosis; D006978:Hypertension, Renovascular / Q000175:diagnosis; D007668:Kidney / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000175:diagnosis; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin; D001192:Arylsulfatases; D005966:Glucuronidase; D000626:Aminopeptidases; D018826:CD13 Antigens
Primenenie dinamicheskoĭ stsintigrafii, rentgenokomp'iuternoĭ tomografii, ul'trazvukovogo skanirovaniia pochek, opredeleniia aktivnosti fermentov i kontsentratsii beta 2-mikroglobulina v syvorotke i moche u bol'nykh arterial'noĭ gipertonieĭ.