Amniotic fluid alpha-fetoprotein measurements by laser immunonephelometry.
A method is described for measuring human alpha-fetoprotein concentration (AFP) in amniotic fluid by laser immunonephelometry showing results comparable with those obtained by radioimmunoassay. Advantages gained with the laser technique lie in its simplicity as a method which avoids use of radioactive materials, a more rapid 2 h turnaround time and a relatively small capital equipment outlay with minimal operating costs. Laser immunonephelometry appears to be an excellent alternative to radioimmunoassay for measuring AFP in amniotic fluid.
D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D006801:Humans; D007158:Immunologic Techniques; D007834:Lasers; D009391:Nephelometry and Turbidimetry / Q000379:methods; D009436:Neural Tube Defects / Q000175:diagnosis*; D011247:Pregnancy; D011863:Radioimmunoassay; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins