title: [Pituitary agenesis in the rat: synthesis of testosterone in fatal testes].
abstract: Testosterone radioimmunological assays were made in testes of 19th day fetuses affected with pituitary agenesis. Testosterone was found very reduced but still present, indicating a basic synthesis, independent of hypophyseal stimulation. General apparatus of affected fetuses is grossly normal. Intervention of chorionic gonadotrophin is hypothesized.
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D010902:Pituitary Gland / Q000002:abnormalities* / Q000196:embryology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013737:Testis / Q000196:embryology* / Q000378:metabolism; D013739:Testosterone / Q000096:biosynthesis*; D001371:trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride / Q000494:pharmacology
chemical_list: D001371:trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; D013739:Testosterone
vernacular_title: Agénésie hypophysaire chez le rat: synthese de testostérone dans les testicules foetaux.