[Brain mitochondrial and nuclear activity of the thyroidectomized rat].
A rapid method of preparation of rat brain mitochondria was described. Oxidative phosphorylation of isolated brain mitochondria was decreased by thyroidectomy. RNA polymerase activity of isolated nuclei was also reduced. Therefore hypothyroidism affects brain subcellular particles as in other tissues.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000096:biosynthesis; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D012313:RNA / Q000096:biosynthesis; D051381:Rats; D011919:Rats, Inbred Strains; D013965:Thyroidectomy; D014158:Transcription, Genetic
D009419:Nerve Tissue Proteins; D012313:RNA; D004247:DNA; D012321:DNA-Directed RNA Polymerases
Activités mitochondriales et nucléaires cérébrales du rat thyroïdectomisé.