Germ-line deletion of genes coding for self-determinants.
D000818:Animals; D000941:Antigens; D001324:Autoantigens; D005075:Biological Evolution; D002872:Chromosome Deletion; D000939:Epitopes; D005796:Genes; D007108:Immune Tolerance; D007135:Immunoglobulin Variable Region / Q000235:genetics; D004676:Myelin Basic Protein / Q000276:immunology*; D013954:Thyroglobulin / Q000276:immunology*
D000941:Antigens; D001324:Autoantigens; D000939:Epitopes; D007135:Immunoglobulin Variable Region; D004676:Myelin Basic Protein; D013954:Thyroglobulin