Immunohistochemical demonstration of somatostatin in the pancreas of fetal and adult sheep.
Pancreatic cells immunoreactive with rabbit anti-somatostatin serum were demonstrated in fetal and adult sheep by immunofluorescence histochemistry. Our observations provide evidence that in the sheep the pancreas is a major site of production of the hormone. It is suggested that the hormone may be important in modulating intra- and extra-islet function.
D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D007120:Immunochemistry; D010179:Pancreas / Q000032:analysis* / Q000196:embryology; D011247:Pregnancy; D012756:Sheep; D013004:Somatostatin / Q000032:analysis*
D013004:Somatostatin