title: [Clinical and morphological manifestations of the pathomorphosis of periarteritis nodosa].
abstract: Clinical, immunological, morphological and immunomorphological data are provided showing the presence of induced (therapeutic) pathomorphosis in Kussmaul-Meier's disease. The conclusion is drawn that at present periarteritis nodosa is characterized by a chronic course with a domination of productive (immunocellular) vasculitis over necrotic (immunocomplex) vasculitis. It is shown that modern polychemotherapy of Kussmaul-Meier's disease favours mainly the correction of humoral immunity alterations while the pathology of cell immunity is retained. It is noted that long interruptions in therapy result in a reversion of the clinical-anatomical manifestations of periarteritis nodosa.
mesh_terms: D000917:Antibody Formation / Q000187:drug effects; D002908:Chronic Disease; D006651:Histocytochemistry; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000473:pathology; D007111:Immunity, Cellular / Q000187:drug effects; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
chemical_list: D007136:Immunoglobulins
vernacular_title: Klinicheskie i morfologicheskie proiavleniia patomorfoza uzelkovogo periarteriita.