title: Genetic and antigenic heterogeneity of different parapoxvirus strains.
abstract: Six stomatitis papulosa and three Orf virus strains were compared by serology and by DNA restriction analysis. A neutralization kinetic study revealed extensive serological cross-reactivity between all strains, but did not allow their classification. Restriction analysis of viral DNAs revealed two distinct groups among the stomatitis papulosa strains while the Orf virus strains formed a third, more heterogeneous group. The large heterogeneity of restriction patterns of parapoxvirus DNAs as compared to those orthopoxviruses is discussed.
mesh_terms: D000956:Antigens, Viral / Q000032:analysis*; D004262:DNA Restriction Enzymes / Q000494:pharmacology; D004279:DNA, Viral / Q000032:analysis*; D000939:Epitopes; D009500:Neutralization Tests; D009923:Orf virus / Q000032:analysis; D011212:Poxviridae / Q000032:analysis* / Q000145:classification / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D004279:DNA, Viral; D000939:Epitopes; D004262:DNA Restriction Enzymes