[Aprotinin-ACD-blood. II. The effect of aprotinin on the release of cellular mediators and enzymes in banked blood (author's transl)].
The concentration of the toxic mediators histamine and serotonin as well as the activity of lactate-dehydrogenase and alkaline phosphatase in banked blood increase significantly during storage. After initial addition of Aprotinin to ACD-Blood the level of these substances remained almost in normal range. The influence of these toxic mediators on the development of shock lung is discussed.
D000469:Alkaline Phosphatase / Q000097:blood; D007611:Aprotinin / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects; D001793:Blood Preservation; D004798:Enzymes / Q000097:blood*; D006632:Histamine / Q000097:blood*; D006801:Humans; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000097:blood; D012701:Serotonin / Q000097:blood*; D013997:Time Factors
D004798:Enzymes; D012701:Serotonin; D006632:Histamine; D007611:Aprotinin; D007770:L-Lactate Dehydrogenase; D000469:Alkaline Phosphatase
Aprotinin -ACD-Blut. II. Der Einfluss von Aprotinin auf die Freisetzung zellulärer Mediatoren und Enzyme im Konservenblut.