title: [Characteristics of the state the population's immunity in the influenza epidemic of 1977-1978].
abstract: During the influenza epidemic of 1977--1978, as well as during the epidemics of 1968 and 1972, the levels of population immunity proved to be a factor which led to the disappearance of the old antigenic variants of group A influenza virus from circulation. At the same time this factor had no influence on the regulating action affecting the selection of new strains. The appearance of the new antigenic variants of group A influenza virus in circulation seemed to depend mainly on the biological properties of the infective agent. The analysis of morbidity among different age groups suggests that immunity against influenza virus A (H1N1), which developed among the population in 1949--1956, determined to a certain extent, resistance to infection during the epidemic of 1977--1978.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D004196:Disease Outbreaks / Q000453:epidemiology*; D000939:Epitopes / Q000032:analysis; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D007251:Influenza, Human / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D012426:Russia; D013045:Species Specificity
chemical_list: D000914:Antibodies, Viral; D000939:Epitopes
vernacular_title: Kharakteristika sostoianiia populiatsionnogo immuniteta v épidemiiu grippa 1977--1978 gg.