Measurement of the 5-hydroxyindoleacetic acid/creatinine ration in the urine of patients with coeliac disease.
Urinary excretion of 5-hydroxyindoleacetic acid and creatinine has been measured in 8-hour collections from adult patients with coeliac disease, and results have been compared with a group of healthy adult controls. Results were expressed as 5-HIAA/creatinine and significantly higher values of this ratio were found in patients with coeliac disease. Measurement of this ratio is a non-invasive technique which is useful in selecting patients with suspected coeliac disease for further investigation.
D000328:Adult; D002446:Celiac Disease / Q000652:urine*; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine*; D008297:Male
D006897:Hydroxyindoleacetic Acid; D003404:Creatinine