title: [Effect of methisoprinol on postoperative immunodepression in subjects with malignant neoplasms].
abstract: The authors investigated the state of immunity, before and after surgery, in a group of 6 methisoprinol-treated patients and in a 10-patient control group both affected by malignant neoplasia. All the patients exhibited various degrees of immuno-depression. Versus the control group the group treated with 1-g methisoprinol injections at the dosage of 4 g daily for 7 days after surgery showed a positive effect on post-surgical immuno-depression.
mesh_terms: D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000627:therapeutic use*; D009369:Neoplasms / Q000601:surgery*; D011183:Postoperative Complications; D013514:Surgical Procedures, Operative / Q000009:adverse effects*
chemical_list: D007288:Inosine; D007542:Inosine Pranobex
vernacular_title: Effetto del metisoprinolo sulla immunodepressione post-operatoria in soggetti affetti da neoplasie maligne.