[Serum lipase assay for clinical use. Critical study (author's transl)].
An accurate, quick, and reproducible method to assay serum lipase activity allowed a parallel study of lipase and amylase in 147 patients. Lipase appeared very specific of pancreatic distress. In acute pancreatitis its increase was constant, frank, quick and lasting. It brought a diagnostic argument superior to the dosages of amylase activities in serum and/or urine. But its value as an evolutive and pronostic test was as much limited. Its interest as a negative argument for differential diagnosis was not superior either. In chronic pancreatic diseases, it gave evidence of massive spread or complications.
D000006:Abdomen, Acute / Q000201:enzymology / Q000209:etiology; D000007:Abdominal Injuries / Q000175:diagnosis; D000208:Acute Disease; D000681:Amylases / Q000097:blood / Q000652:urine; D002908:Chronic Disease; D004796:Clinical Enzyme Tests; D006801:Humans; D008049:Lipase / Q000097:blood*; D010182:Pancreatic Diseases / Q000175:diagnosis; D010195:Pancreatitis / Q000175:diagnosis*; D011379:Prognosis
D008049:Lipase; D000681:Amylases
Dosage de la lipase sérique. Etude critique.