title: Follow-up studies of visual potentials in multiple sclerosis evoked by checkerboard and foveal stimulation.
abstract: Visual cortical potentials were evoked by reversal of a checkerboard pattern and a small quadrangular foveal stimulus. Examination of 68 patients with MS showed the highest detection rate for abnormality of VEPs with a combination of both methods. Follow-up studies revealed changes (improvement or impairment) of VEP amplitudes or latencies in nearly half of the patients. Most of the changes were correlated with a history of acute optic neuritis. For the detection of changes the foveal stimulus is preferable to the checkerboard pattern.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D009902:Optic Neuritis / Q000150:complications / Q000503:physiopathology; D010775:Photic Stimulation / Q000379:methods*; D014792:Visual Acuity; D014796:Visual Perception
chemical_list: D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone