title: The fine structure of epithelial cells in normal and pathological buccal mucosa. III. Pathological changes in spinous, transitional and superficial cells in the erosive type of lichen planus.
abstract: Superficial, transitional and polygonal buccal epithelial cells from patients with the erosive type of lichen planus were compared with similar cells from non-keratinizing human buccal mucosa. Transitional cells from non-keratinizing buccal mucosa had glycogen lakes and membrane-coating granules with electron dense cores. Surface cells were not keratinized and pathological cells were less granular. In lichen planus membrane-coating granules were numerous, markedly electron dense, and some showed an internal lamellar structure. Surface cells were keratotic or parakeratotic. Processes of macrophages were associated with the pathological membrane-coating granules.
mesh_terms: D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D005881:Gingiva / Q000648:ultrastructure; D006003:Glycogen / Q000378:metabolism; D007425:Intracellular Membranes / Q000648:ultrastructure; D007633:Keratins / Q000378:metabolism; D008010:Lichen Planus / Q000473:pathology*; D008854:Microscopy, Electron; D009059:Mouth Diseases / Q000473:pathology; D009061:Mouth Mucosa / Q000648:ultrastructure*; D009940:Organoids / Q000648:ultrastructure
chemical_list: D007633:Keratins; D006003:Glycogen