Haemoglobin O Arab, beta-thalassaemia and glucose-6-phosphate dehydrogenase deficiency in a Hungarian family.
A 29-year-old Hungarian woman was found to be double heterozygote for Hb O Arab and beta-thalassaemia. Haemolytic anaemia became manifest during her second pregnancy. In the course of genetic studies G-6-PD deficiency was also detected in the family. The patient originates from a North-Eastern part of Hungary which had been hydrogeologically isolated during past centuries.
D000328:Adult; D000743:Anemia, Hemolytic / Q000150:complications* / Q000235:genetics; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D006814:Hungary; D010375:Pedigree; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000235:genetics; D013789:Thalassemia / Q000150:complications* / Q000235:genetics
D006455:Hemoglobins, Abnormal