[Abnormal serum iron carrier in a case of malignant histiocytosis (author's transl)].
A patient with malignant histiocytosis had an iron plasmatic concentration above 600 gamma/100 ml. An abnormal iron-binding protein incompletely saturated is demonstrated in the plasma. This protein has an electrophoretic migration near the alpha 2 globulins and no immunological reactions with antitransferrin and antiferritin antibodies. Its affinity for iron is less and its molecular weight is greater than the one of transferrin. Such a protein has not already been described in the plasma and its presence should be related to the malignant disease.
D000510:Alpha-Globulins / Q000378:metabolism; D001797:Blood Protein Electrophoresis; D002352:Carrier Proteins / Q000097:blood*; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood*; D008206:Lymphatic Diseases / Q000097:blood*; D008875:Middle Aged; D011863:Radioimmunoassay; D014168:Transferrin / Q000378:metabolism
D000510:Alpha-Globulins; D002352:Carrier Proteins; D014168:Transferrin; D007501:Iron
Transporteur sérique anormal du fer au cours d'une histiocytose maligne.