[Secondary fluorescence of intraocular vessels of the anterior segment of the rat eye after local drug application (author's transl)].
After local application of gentamycine, dexamethasone and tropicamide to rat eyes, no effect was observed on the permeability of the vascular wall of the iris and ciliary body compared with fluorescein-Na. Nor were there any changes in vessel caliber. The constriction of the dye column observed in corneal neovascularizations was not seen in the (normal) iris vessels and the vessels of the ciliary body. With regard to the iris region, however, this might be due to mechanical causes and/or the possibility that vessels of different origins react differently.
D000287:Administration, Topical; D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D002924:Ciliary Body / Q000098:blood supply / Q000187:drug effects*; D003907:Dexamethasone / Q000008:administration & dosage / Q000494:pharmacology; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology; D007498:Iris / Q000098:blood supply / Q000187:drug effects*; D008856:Microscopy, Fluorescence; D009389:Neovascularization, Pathologic; D051381:Rats; D014331:Tropicamide / Q000008:administration & dosage / Q000494:pharmacology
D005839:Gentamicins; D003907:Dexamethasone; D014331:Tropicamide
Die sekundäre Fluoreszenz intraokularer Vorderabschnittsgefässe des Rattenauges nach lokal applizierten Medikamenten.