title: Substance P activity in the bullfrog retina: localization and identification in several vertebrate species.
abstract: Immunoreactive substance P is present in the bullfrog retina, possibly in two types of stratified amacrine cells, with their somas in the inner nuclear layer and their neuronal processes entering the inner plexiform layer and ramifying in sublayers 3 or 4 (or both). Occasionally, polygonal somas positive for substance P were found in the ganglion cell layer. Approximately 75 percent of the cell bodies positive for substance P and 65 percent of the radioimmunoassayable substance P were found in the superior half of the frog retina. On the basis of high-performance liquid chromatography, the immunoreactive substance P in the neural retina of the rat, monkey, or chick is similar to synthetic substance P, whereas this is not true of the immunoreactive substance P in the bullfrog or carp retina.
mesh_terms: D000818:Animals; D002645:Chickens; D005455:Fluorescent Antibody Technique; D008251:Macaca; D011892:Rana catesbeiana; D051381:Rats; D012160:Retina / Q000032:analysis / Q000166:cytology*; D013045:Species Specificity; D013373:Substance P / Q000032:analysis*
chemical_list: D013373:Substance P