Serotonergic control of experimental aggression.
The role played by the inhibitory control of brain functions appears reportedly essential in the regulation of emotions and behavior, and is of great relevance in explaining the behavioral changes that follow induced or spontaneous impairment of the serotonergic system of the brain. As a matter of fact, numerous evidence indicate that genetic predisposition and induced or acquired defects of serotonergic inhibitory control greatly concur to precipitate anomalous strong aggression. The cluster of symptoms presented by laboratory rats in consequence of the serotonergic discontrol confers to laboratory experiments the value of a tool aimed at a better understanding of the biological mechanisms which underlie pathological aggression and violence.
D000367:Age Factors; D000374:Aggression / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008297:Male; D009433:Neural Inhibition; D009434:Neural Pathways / Q000502:physiology; D011235:Predatory Behavior / Q000502:physiology; D051381:Rats; D012701:Serotonin / Q000502:physiology*; D012727:Sex Characteristics
D014150:Antipsychotic Agents; D012701:Serotonin