title: [Effect of artificial gravity during space flight on protein and RNA concentration in motoneurons of the anterior horns of the spinal cord in rats].
abstract: The content of protein and RNA in motoneurons of anterior horns of the spinal cord of rats flown for 18.5 days aboard the biosatellite Cosmos--936 was measured. Ten rats were exposed to weightlessness and 9 rats to artificial gravity. The RNA content in both rat groups remained at the preflight level 4.5--9.5 hours after recovery. The protein content in the motoneuronal cytoplasm of weightless and centrifuged rats was by 42 and 30% lower than in vivarium control. The protein content in the motoneuronal nuclei of the above rats was by 31 and 24% lower than in the controls. Twenty-five days postflight the RNA content in weightless rats was by 22% higher than and in centrifuged rats similar to that in the controls. The protein content in the cytoplasm returned to normal in both rat groups, whereas that in the nuclei of weightless rats was by 37% higher than in the controls.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000032:analysis / Q000648:ultrastructure; D003593:Cytoplasm / Q000032:analysis; D006112:Gravitation; D009046:Motor Neurons / Q000032:analysis* / Q000648:ultrastructure; D009419:Nerve Tissue Proteins / Q000032:analysis; D012313:RNA / Q000032:analysis; D051381:Rats; D013026:Space Flight; D013116:Spinal Cord / Q000032:analysis* / Q000166:cytology
chemical_list: D009419:Nerve Tissue Proteins; D012313:RNA
vernacular_title: Vliianie iskusstvennoĭ sily tiazhesti v kosmicheskom polete na soderzhanie belkov i RNK v motoneĭronakh perednikh rogov spinnogo mozga krysy.