[Anticellular action of alpha-interferons of various origins].
The results of the study of the anticellular effect of alpha-interferons of various origins (human, porcine, and bovine) on the growth of human lymphoblastoid cells (Namalva and J-96). Both homologous (human) and heterologous (porcine and bovine) leukocyte interferons produced a similar anticellular effect on the cells under study. All 3 types of interferon inhibited proliferation of lymphoblastoid cells. No such effect of these interferons on the control (diploid) cells was observed.
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002051:Burkitt Lymphoma / Q000628:therapy; D002417:Cattle; D002478:Cells, Cultured; D004353:Drug Evaluation, Preclinical; D006801:Humans; D066298:In Vitro Techniques; D007372:Interferons / Q000627:therapeutic use*; D007951:Leukemia, Myeloid / Q000628:therapy; D013552:Swine; D013997:Time Factors
D000970:Antineoplastic Agents; D007372:Interferons
Antikletochnoe deĭstvie al'fa-interferonov razlichnogo proiskhozhdeniia.