[Reversibility of alterations induced by sexual steroids in various serum protein fractions, following application of hormonal contraceptives (author's transl)].
Reversibility of changes induced by sexual steroids was studied in 19 different serum protein fractions of 20 women. The following preparations were available for testing: Gravistat (ethinyl-oestradiol/norgestrel), Non-Ovlon (ethinyloestradiol/norethisterone-acetate), Ovosiston (mestranol/chlormadinone-acetate), and Deposiston (ethinyloestradiol-sulphonate/norethisterone-acetate). The tests were made towards the end of the 24th cycle on the pill and in the first cycle thereafter.--The proteins tested were found to be affected in a differentiated way and, throughout, depending on oestrogen levels. Reversal was rapid, but the phase of restitution usually was longer than the period of testing and follow-up. The long-lasting action of Deposiston was visualised also in its "reversal effect".
D001798:Blood Proteins / Q000032:analysis*; D002570:Ceruloplasmin / Q000032:analysis; D003276:Contraceptives, Oral / Q000494:pharmacology*; D003278:Contraceptives, Oral, Hormonal / Q000494:pharmacology*; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008259:Macroglobulins / Q000032:analysis; D012177:Retinol-Binding Proteins / Q000032:analysis; D013997:Time Factors; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis
D001798:Blood Proteins; D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D006023:Glycoproteins; D007136:Immunoglobulins; D008259:Macroglobulins; D012177:Retinol-Binding Proteins; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D000509:alpha-Fetoproteins; D002570:Ceruloplasmin
Zur Reversibilität sexualsteroidinduzierter Veränderungen verschiedener Serumproteinfraktionen nach Applikation hormonaler Kontrazeptiva.