title: Segmental amplification  in a satellite DNA: restriction enzyme analysis of the major satellite of Macropus rufogriseus.
abstract: The 1.708 g/cc satellite DNA of the red necked wallaby is shown to consist of a number of related families of sequences arranged in tandem arrays. Particular families are subpopulations of other families; their distribution supports a model of successive amplification events during the generation of the satellite. In each amplification episode one 2,500 bp unit is multiplied into a tandemly repeated array of that unit (segmental amplification). The 1.708 g/cc sequences can be detected in related kangaroo species in much reduced amount, and with changes to the long order periodicity of the repeat units.
mesh_terms: D000818:Animals; D001483:Base Sequence; D004261:DNA Replication; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004276:DNA, Satellite / Q000032:analysis / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D007614:Macropodidae / Q000235:genetics*; D008394:Marsupialia / Q000235:genetics*; D012313:RNA / Q000096:biosynthesis; D014158:Transcription, Genetic
chemical_list: D004276:DNA, Satellite; D012313:RNA; D004262:DNA Restriction Enzymes