[Detection and localization of organ-specific antigens at early stages of lens differentiation in the rat embryo (author's transl)].
By means of liver-absorbed rabbit anti-adult rat lens sera, and by using the indirect immunoperoxidase technique, lens-specific antigens are detectable in a few isolated cells, or in small groups of cells, of the placode shortly after the onset of invagination. In the deeply invaginated lens rudiment, all the cells, exept those in the area adjacent to the ectoderm (presumptive lens epithelial cells) display a positive reaction. Once the lens vesicle has formed, all the cells contain detectable amounts of lens-specific antigens.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D002454:Cell Differentiation; D000939:Epitopes; D005260:Female; D007122:Immunoelectrophoresis; D007124:Immunoenzyme Techniques; D007908:Lens, Crystalline / Q000196:embryology / Q000276:immunology*; D051381:Rats
D000941:Antigens; D000939:Epitopes
Mise en évidence d'antigènes spécifiques aux stades précoces de la différenciation du cristallin chez l'embryon de rat.