title: Population distribution of human salivary amylases: differential inhibition by wheat protein.
abstract: Based upon response to an inhibitor from wheat gliadin, 80 random samples of human salivary amylase were separated into three phenotypic groups. Each phenotype occurred with a high frequency rendering this a polymorphinc locus. The susceptibility to the inhibitor may be a useful marker for studies of tendency to caries and periodontal disease as well as for studies of genetic variation and linkage.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000681:Amylases / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D002170:Canada; D002648:Child; D002675:Child, Preschool; D005260:Female; D005828:Genetics, Population; D005903:Gliadin / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D010940:Plant Proteins / Q000494:pharmacology*; D012463:Saliva / Q000201:enzymology*; D014908:Triticum; D014481:United States
chemical_list: D010940:Plant Proteins; D005903:Gliadin; D000681:Amylases