The interrelations of some humoral factors of resistance with the prevalence of respiratory diseases in children. I. The differences among the protein levels in healthy and ill children.
The prevalence of respiratory diseases was followed in a group of 80 children (39 boys and 41 girls) of mean age 12.4 +/- 0.9 years during the part of school year (November - May incl.). The specimen of blood was taken from all studied children before the study started and the values of nine serum proteins were measured (IgG, IgA, IgM, IgE, alfa 1-antitrypsin = A 1-AT, transferrin = TRF, ceruloplasmin = CPL, alpha 2-macroglobulin = A 2M, lysozyme = LYS), as well as levels of two secretory proteins in saliva (sIgA and sLYS). The difference between the subgroup of boys, who fall into some respiratory illness during the observation time, and those who remain healthy, did not reach the level of significance. In contrast, the girls subgroup revealed significantly higher respiratory morbidity. With those girls, who remained healthy, the levels of serum IgE were highly increased and A 1-AT level weakly increased compared to ill girls. The level of TRF and CPL were significantly decreased with the healthy girls.
D001798:Blood Proteins / Q000032:analysis*; D002570:Ceruloplasmin / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D012141:Respiratory Tract Infections / Q000097:blood / Q000276:immunology*; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D001798:Blood Proteins; D007136:Immunoglobulins; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D002570:Ceruloplasmin