Serological analysis and pathogenic potentials of Wangiella dermatitidis isolated from bats.
Five isolates of Wangiella dermatitidis from macroscopically asymptomatic bats were analysed by the agar-gel immunodiffusion tests and the mouse inoculation studies on virulence. No cross-reactivity among the antigens and antisera prepared from the bat and human isolates was observed. The fungus was shown to be neurotropic, of low infectivity and not implicated as a potential opportunistic pathogen. Differences in the antigenic composition and pathogenic potentials between isolates of the same fungus of different origins may reflect adaptation of the fungus in different hosts.
D000818:Animals; D000946:Antigens, Fungal / Q000032:analysis; D002685:Chiroptera / Q000382:microbiology*; D003348:Cortisone / Q000494:pharmacology; D003429:Cross Reactions; D000939:Epitopes; D006801:Humans; D051379:Mice; D003904:Mitosporic Fungi / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D009181:Mycoses; D009461:Neurologic Manifestations
D000946:Antigens, Fungal; D000939:Epitopes; D003348:Cortisone