Effect of a deproteinized blood extract on the recovery of blood circulation in an ischaemic skin lesion.
An experimental model was used to study the revascularization of an ischaemic skin lesion and the effect on this process of the blood extract Solcoseryl. Under the conditions given in the experiment, restoration of the circulation was by 2 modes--re-flow in the original vessels, and neovascularization. Solcoseryl given daily i.p. encouraged the re-flow phenomenon and therefore, by improving the microcirculation and nutrition, the healing of the ischaemic lesions.
D000183:Actihaemyl / Q000627:therapeutic use*; D000818:Animals; D005260:Female; D007511:Ischemia / Q000188:drug therapy*; D008833:Microcirculation / Q000187:drug effects; D009389:Neovascularization, Pathologic / Q000187:drug effects; D011312:Pressure; D051381:Rats; D012867:Skin / Q000098:blood supply*; D014020:Tissue Extracts / Q000627:therapeutic use*
D014020:Tissue Extracts; D000183:Actihaemyl