title: [Behavior of reticulocytes of the peripheral blood after whole-body irradiation and stimulation of the bone marrow - a contribution for the detection of radiation-induced changes in cells of the peripheral blood].
abstract: The relative reticulocyte content and the average Fe-uptake of peripheral reticulocytes were investigated in rats after a blood loss and whole body irradiation as well after a combined treatment for a time of 15 days. The acute loss of blood caused a rapid increase of cellular uptake within 24 hours, whereas after irradiation a considerable diminution could be observed. In addition to a direct stimulation or inhibition a considerable diminution could be observed. In addition to a direct stimulation or inhibition of bone-marrow activity a direct impact of reticulocytes by blood loss and irradiation is discussed.
mesh_terms: D000818:Animals; D001810:Blood Volume; D001853:Bone Marrow / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004906:Erythrocyte Count; D005260:Female; D007501:Iron / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012156:Reticulocytes / Q000378:metabolism / Q000528:radiation effects*; D014916:Whole-Body Irradiation
chemical_list: D007501:Iron
vernacular_title: Das Verhalten von Retikulozyten des peripheren Blutes nach Ganzkörperbestrahlung und Stimulation des Knochenmarks -- ein Beitrag zum Nachweis strahlenbedingter Veränderungen an Zellen des peripheren Blutes.