title: Macular lesions in blacks with the presumed ocular histoplasmosis syndrome.
abstract: Six black patients had fundus lesions diagnostic of the presumed ocular histoplasmosis syndrome. All patients had peripapillary changes or peripheral punched-out chorioretinal lesions, or both. Five of the six had macular subretinal neovascularization, disciform scarring, or an atrophic macular lesion, and one patient had a macular hole; four of five patients tested had a positive histoplasmin skin test. The macular involvement was bilateral in three of the six cases. HLA B-7 was present in one of four patients who had HLA typing. Macular involvement can occur in blacks with the presumed ocular histoplasmosis syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D001284:Atrophy / Q000473:pathology; D044383:Black People; D002648:Child; D002675:Child, Preschool; D002829:Choroid / Q000473:pathology; D005128:Eye Diseases / Q000276:immunology / Q000473:pathology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006660:Histoplasmosis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D012160:Retina / Q000473:pathology
chemical_list: D006680:HLA Antigens