Nucleotidic cofactors and the origin of the genetic code.
In this article it is suggested that the first coding system started from specific interactions between the nucleotide part of nucleotidic cofactors and enzymes. These interactions generated a first primitive code of four words of one letter each for the four primittive amino acids (phenylalanine, lysine, glycine and proline); when the triplet code (which allowed the integration of 20 amino acids into proteins) progressively appeared, it must have been modulated by the existence of this first coding system.
D001483:Base Sequence; D005075:Biological Evolution; D003067:Coenzymes; D004247:DNA; D005823:Genetics; D009711:Nucleotides; D012313:RNA
D003067:Coenzymes; D009711:Nucleotides; D012313:RNA; D004247:DNA