Rabbits immunized against b6 allotype express similar anti-b6 idiotopes.
Similar idiotopes are detected on anti-allotypic antibodies synthesized by all rabbits immunized against the b6 allotype. The expression of similar idiotypes on anti-b6 antibodies has been found in rabbits of all VHa allotypic types thus far studies. For their expression, these idiotypes require the interaction between VL and VH domains.
D000818:Animals; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D000939:Epitopes; D007106:Immune Sera / Q000494:pharmacology; D007114:Immunization; D007126:Immunoglobulin Allotypes; D007143:Immunoglobulin Heavy Chains; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D007147:Immunoglobulin Light Chains; D007135:Immunoglobulin Variable Region; D007525:Isoelectric Focusing; D010641:Phenotype; D011817:Rabbits
D000939:Epitopes; D007106:Immune Sera; D007126:Immunoglobulin Allotypes; D007143:Immunoglobulin Heavy Chains; D007130:Immunoglobulin Idiotypes; D007147:Immunoglobulin Light Chains; D007135:Immunoglobulin Variable Region