Substance P suppresses stress-induced eating.
Parenterally administered substance P suppressed stress-induced eating (resulting from mild tail pinch) in a dose-related manner, whereas at similar or higher doses of substance P starvation-induced eating was uneffected. This specific effect of substance P on stress-induced eating is possibly associated with alterations of exogenous substance P of the normal modulation of pain transmission.
D000818:Animals; D004435:Eating / Q000187:drug effects*; D010146:Pain / Q000503:physiopathology; D051381:Rats; D013217:Starvation / Q000503:physiopathology; D013312:Stress, Physiological / Q000503:physiopathology*; D013373:Substance P / Q000494:pharmacology*
D013373:Substance P