title: Structural relationships between parenchymal and stromal elements in the pars intermedia of the rat adenohypophysis as demonstrated by extracellular space markers.
abstract: The pars intermedia (PI) of the rat adenohypophysis was studied by light and transmission electron microscopy after conventional staining as well as ruthenium red staining, and after systemic injection of horseradish peroxidase. The studies disclose a complex and constant system of two channel types (Type I and Type II channels) formed by PI cells with specific relationships to a very rich nerve supply, to each other, and to a stellate cell type proposed here to represent an element of neuroglia. The channel system could perform a function in the movement of fluids and solutes within the PI which is verturally avascular in the rat as well as in other mammals.
mesh_terms: D000818:Animals; D005110:Extracellular Space / Q000378:metabolism*; D006735:Horseradish Peroxidase; D007365:Intercellular Junctions / Q000648:ultrastructure; D010903:Pituitary Gland, Anterior / Q000166:cytology* / Q000294:innervation / Q000378:metabolism; D051381:Rats; D012430:Ruthenium Red
chemical_list: D012430:Ruthenium Red; D006735:Horseradish Peroxidase