[Use of natural kallikrein-protease inhibitors (contrical and gordox) in the therapy of acute myocardial infarct].
The paper reports on the efficacy of the protease inhibitors Contrycal and Hordox in acute myocardial infarction. The authors observed 154 patients, of whom 50 constituted the control group. They used to watch the process in the myocardium with biochemical, radioimmune and electrocardiographic methods. It was established that Contrycal (Hordox) used in the combined therapy of acute myocardial infarction during the first hours of the disease is effective.
D000328:Adult; D000368:Aged; D007611:Aprotinin / Q000627:therapeutic use*; D004341:Drug Evaluation; D004562:Electrocardiography; D006801:Humans; D007610:Kallikreins / Q000037:antagonists & inhibitors*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D011480:Protease Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014361:Trypsin Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*
D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; C011475:gordox; D007611:Aprotinin; D007610:Kallikreins
Primenenie estestvennykh kallikrein-proteaznykh ingibitorov (kontrikala, gordoksa) v terapii ostrogo infarkta miokarda.