title: Hereditary palmo-plantar keratoderma: incidence of dermatophyte infections and the results of topical treatment with retinoic acid.
abstract: Thirty-four patients with hereditary palmo-plantar keratoderma (HPPK) were examined with regard  to dermatophyte infections. Twenty-two of the patients (65%) had dermatophytosis, a figure indicating a predisposition of this type of infection. E. floccosum was found in %0% of the HPPK patients as compared with 17% of the dermatophytoses of palms and soles in non-HPPK patients (p less than 0.01). Topical treatment of HPPK with 0.05% retinoic acid without occlusion had no observable effect.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D002176:Candida albicans / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003881:Dermatomycoses / Q000150:complications* / Q000209:etiology; D004821:Epidermophyton / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007223:Infant; D007645:Keratoderma, Palmoplantar / Q000150:complications / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D014249:Trichophyton / Q000302:isolation & purification
chemical_list: D014212:Tretinoin