Combined antiviral effects of flavonoids and 5-ethyl-2'-deoxyuridine on the multiplication of herpesviruses.
The combined antiviral effects of quercetin, quercitrin and 5-ethyl-2'-deoxyuridine on the multiplication of herpes simplex virus type 1 (HSV-1) and pseudorabies virus were studied in vitro by the yield reduction test. Quercetin in combination with 5-ethyl-2'-deoxyuridine had an additive antiviral effect on either herpes-virus. The combined application of quercitrin and 5-ethyl-2'-deoxyuridine showed a synergic effect on pseudorabies virus.
D000998:Antiviral Agents; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000494:pharmacology; D004357:Drug Synergism; D005419:Flavonoids / Q000494:pharmacology*; D011558:Herpesvirus 1, Suid / Q000187:drug effects*; D011794:Quercetin / Q000031:analogs & derivatives / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects*
D000998:Antiviral Agents; D005419:Flavonoids; C022811:edoxudin; C012526:quercitrin; D011794:Quercetin; D003857:Deoxyuridine