[Immunochemical study of alpha-1 organospecific antigen in different sections of the brain and CNS tumors].
By immunochemical methods the most high concentrations of alpha-1 organ specific antigen of the brain were revealed in tissue extracts of the spinal marrow, cerebral trunk, hypothalamus; its lower concentrations--in the cerebral cortex, cerebellum, optic nerve, white substance of the hemispheres and pineal gland. This protein was not found in the hypophysis. In tumors of neuroectodermal origin the antigen was found in high concentrations. In an group of meningiomas alpha-1 organ specific brain antigen was detected in tumors of meningotheliomatous type, but it was absent in tumors of mixed and fibroblastic type, this permitted suggesting a neuroectodermal origin of tumors of the first type and ectomesenchymal one of the second type.
D000510:Alpha-Globulins / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D001932:Brain Neoplasms / Q000276:immunology*; D002490:Central Nervous System / Q000276:immunology*; D000939:Epitopes / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D009928:Organ Specificity
D000510:Alpha-Globulins; D000951:Antigens, Neoplasm; D000939:Epitopes
Immunokhimicheskoe izuchenie al'fa-1 organospetsificheskogo antigena v razlichnykh otdelakh mozga i opukholiakh TsNS.