[Rhizomelic pseudopolyarthritis and Horton's disease. A search for correlations with HLA system, HB virus and Beta 2 microglobulin (author's transl)].
The authors studied 31 patients with either rhizomelic pseudopolyarthritis or Horton's disease. Contrary to others, they found no significant correlation between these diseases and hepatitis B virus infection or HLA gene. However, beta 2 microglobulin assays showed that it was significantly higher in these patients than in a control population. In the absence of close correlation between beta 2 microglobulin levels and those of inflammatory proteins, it is suggested that the rise in microglobulin reflected an immunological mechanism requiring further investigation.
D000368:Aged; D001609:Beta-Globulins / Q000032:analysis*; D005260:Female; D013700:Giant Cell Arteritis / Q000209:etiology*; D006680:HLA Antigens / Q000235:genetics*; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D010641:Phenotype; D011111:Polymyalgia Rheumatica / Q000209:etiology*; D012189:Retrospective Studies; D001613:beta 2-Microglobulin / Q000032:analysis*
D001609:Beta-Globulins; D006680:HLA Antigens; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D001613:beta 2-Microglobulin
Psuedo-polyarthrite rhizomélique et maladie de Horton. Recherche de corrélation avec le systéme H.L.A., le virus HB et la beta 2 microglobuline.