The effect of procainamide on delayed activation potentials in a patient with ventricular tachycardia.
In a patient with ventricular tachycardia and previous myocardial infarction, delayed activation potentials were recorded from a region of the posterolateral wall of the left ventricle at electrophysiological study. Procainamide, administered intravenously, initially caused increased delay and later, in higher dosage, second-degree block of the delayed potentials.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D004285:Dogs; D004562:Electrocardiography; D006327:Heart Block / Q000188:drug therapy; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D011342:Procainamide / Q000494:pharmacology*; D013610:Tachycardia / Q000503:physiopathology*
D000889:Anti-Arrhythmia Agents; D011342:Procainamide