[Kinin system of the blood and myocardium in monitored limitation of the coronary blood flow].
Components of the blood kinin system as well as concentration of kininogen and kininase activity were studied in various myocardial structures after controlled restriction of coronary circulation by 30%, 50%, 70% and 90% within 30 min. As blood supply of heart decreased, activation of kallikrein, decrease in content of kininogen and inhibition of kininase activity in blood were observed. These alterations were detected also in myocardium; they were especially distinct in the ischemic zone.
D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D003326:Coronary Circulation; D003327:Coronary Disease / Q000378:metabolism; D004285:Dogs; D007610:Kallikreins / Q000378:metabolism; D007704:Kininogens / Q000378:metabolism; D007705:Kinins / Q000378:metabolism*; D001121:Lysine Carboxypeptidase / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011288:Prekallikrein / Q000378:metabolism; D000511:alpha-Macroglobulins / Q000378:metabolism
D007704:Kininogens; D007705:Kinins; D000511:alpha-Macroglobulins; D011288:Prekallikrein; D002265:Carboxylic Ester Hydrolases; C019763:benzoylarginine ethyl esterase; D001121:Lysine Carboxypeptidase; D007610:Kallikreins
Kininovaia sistema krovi i miokarda pri dozirovannom ogranichenii koronarnogo krovotoka.