Antigenic relatedness of Proteus mirabilis and Escherichia coli with rat tissues and human erythrocytes.
The cross-reactions of rat kidney with P. mirabilis and E. coli, and of rat urinary bladder with P. mirabilis were established by precipitation, agglutination and immunofluorescence methods. One of the cross-reactive bacterial components was the lipopolysaccharide. Human erythrocytes of Blood-groups A, O and AB were agglutinated by antisera to P. mirabilis and E. coli. The role of antigenic relatedness in urinary tract infections is discussed.
D000372:Agglutination Tests; D000818:Animals; D000941:Antigens / Q000276:immunology*; D000942:Antigens, Bacterial; D003429:Cross Reactions; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology*; D004926:Escherichia coli / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D005779:Immunodiffusion; D007668:Kidney / Q000276:immunology*; D011513:Proteus mirabilis / Q000276:immunology*; D051381:Rats; D001743:Urinary Bladder / Q000276:immunology*
D000941:Antigens; D000942:Antigens, Bacterial; D000939:Epitopes