[Effect of interferon on tumor cell growth inhibition by human peripheral leukocytes. II. Characteristics of effector cells].
The authors clarified the characteristics of effector cells of which inhibitory activity against the tumor cell growth was enhanced by interferon (IF). These cells adhered to nylon wool, but they did not adhere to a glass surface. They showed the EA-rosettees formation, but they did not show the E-rosett formation. This activity was diminished by trypsinization, X-ray irradiation and treatment with hydrocortisone and progesterone. It was not changed by the addition of aggregated Ig. In summary, the effector cells in the present study could not be identical to NK cells.
D002448:Cell Adhesion / Q000187:drug effects; D002472:Cell Transformation, Viral / Q000187:drug effects*; D006367:HeLa Cells / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000276:immunology; D007962:Leukocytes / Q000187:drug effects*; D009757:Nylons; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects / Q000502:physiology*; D012397:Rosette Formation
D009757:Nylons; D007372:Interferons
Effet de l'interféron sur l'inhibition de la croissance des cellules malignes par les leucocytes périphériques humains. II. Quelques caractéristiques des cellules-effecteurs.