Successful treatment of actinic reticuloid induced by whole-body topical application of mechlorethamine.
A man suffering from actinic reticuloid for 2 years showed highly abnormal light sensitivity over a broad action spectrum. He has been successfully treated with daily whole-body topical applications of mechlorethamine, initially for 4 weeks and after a 2-month interruption, for 3 weeks. Gauzes moistened with the same solution were placed over lichenified areas for 10-15 min. His skin became normal pale and the lichenification decreased. After treatment his tolerance for daylight increased.
D000287:Administration, Topical; D000368:Aged; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage / Q000627:therapeutic use*; D010787:Photosensitivity Disorders / Q000188:drug therapy*; D014466:Ultraviolet Rays
D008466:Mechlorethamine