title: Disc leak in the pathogenesis of posterior retinal degenerations.
abstract: Pathogenesis of the posterior retinal degenerations and the role of argon laser para-disc coagulation in its treatment. The posterior retinopathies sometimes follow the degeneration of the retinal pigment epithelium with a release of the hypothetical vasoproliferative factor. There is clinical evidence to show that a slow degeneration of the retinal pigment epithelium also produces a vasoproliferation from the circulation which comes from the choroidal vessels supplying the disc. Treatment by argon laser at the disc margin inhibits the rate of degeneration, and extension of the vasoproliferation.
mesh_terms: D002829:Choroid / Q000098:blood supply; D006801:Humans; D053685:Laser Therapy; D008268:Macular Degeneration / Q000209:etiology; D009389:Neovascularization, Pathologic; D009898:Optic Disk / Q000098:blood supply*; D010857:Pigment Epithelium of Eye; D012162:Retinal Degeneration / Q000209:etiology* / Q000601:surgery