title: [Role of thyroid gland hormones in thermoregulatory reactions during adaptation to high altitude].
abstract: The influence of thyroid hormone in thermogenesis of animals adapting to high altitude for different periods were studied in white rats. The adaptation to high altitude hypoxia decreased reaction of the organism to cold. The antithyroid injection of mercazolil potentiated the hypoxia action in cold thermogenesis and lowered sharply the body temperature stability in cooling. The analogous injection of triiodthyronine reduced the hypoxia influence on the thermogenesis and increased the contribution of the contractile heat production in the thermoregulative metabolism. The data suggest that one of the reasons of the low heat effect of the muscle contraction in adaptation to hypoxia may be the functional weakening of the thyroid gland.
mesh_terms: D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology; D001833:Body Temperature Regulation; D000860:Hypoxia / Q000503:physiopathology; D008297:Male; D008713:Methimazole / Q000494:pharmacology; D009132:Muscles / Q000502:physiology; D010101:Oxygen Consumption; D051381:Rats; D013696:Temperature; D013963:Thyroid Hormones / Q000502:physiology*; D014284:Triiodothyronine / Q000494:pharmacology
chemical_list: D013956:Antithyroid Agents; D013963:Thyroid Hormones; D014284:Triiodothyronine; D008713:Methimazole
vernacular_title: O roli gormonov shchitovidnoĭ zhelezy v reaktsiiakh termoreguliatsii pri adaptatsii k vysokogor'iu.