[Treatment of head and neck tumors by the combination of bleomycin, methotrexate, cyclophosphamide and corticoid (author's transl)].
The authors report on their findings after analysing the results of an intermittent combination chemotherapy with Bleomycin (B.L.M.), Methotrexate (M.T.X.), Cyclophosphamide and corticoid (B.M.E.M.), in 117 cases of tumors of the Head and Neck. There were 30,0% of complete remission and 77,8% of responsiveness mors. Significant response rates were achieved with this B.M.E.M. combination therapy in: both advanced and not advanced tumors, both well and poor differentiated carcinomas; both exophitic and endophytic tumors.
D001761:Bleomycin / Q000008:administration & dosage*; D002280:Basal Cell Carcinoma / Q000188:drug therapy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D008048:Lip Neoplasms / Q000188:drug therapy; D008545:Melanoma / Q000188:drug therapy; D008727:Methotrexate / Q000008:administration & dosage*; D011241:Prednisone / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000188:drug therapy
D001761:Bleomycin; D003520:Cyclophosphamide; D011241:Prednisone; D008727:Methotrexate
Traitement des tumeurs de la tête et du cou par une association de bléomycine, méthotréxate, cyclophosphamide et corticoïde.