title: Sensorineural and vascular changes in an ear with acoustic neurinoma.
abstract: The temporal bones from a 55-year-old woman with deafness and dizzy spells caused by a right-sided acoustic neurinoma were examined by the techniques of microdissection, surface preparations, and celloidin sections. Sensorineural degeneration was present in the basal end of the right cochlea but was not severe enough to explain the deafness. The compression of the cochlear nerve by the tumor was postulated to have caused deafness by injury to neurons adjacent and central to the tumor. There was profound degeneration of the vestibular nerve and sensory cells. A gelatinous material occluded the scala vestibuli, and the vestibular fluid spaces contained an amorphous proteinaceous substance. Fewer erythrocytes were seen in the vessels of the right cochlea, but there was no atrophy of capillaries to indicate long-term reduction of circulation. Vasculoneogenesis of venous vessels had occurred in the scala tympani, probably as a result of venous stasis.
mesh_terms: D008267:Acoustic Maculae / Q000473:pathology; D001299:Audiometry; D001489:Basilar Membrane / Q000473:pathology; D003051:Cochlea / Q000098:blood supply* / Q000473:pathology; D003638:Deafness / Q000209:etiology* / Q000473:pathology; D004584:Electronystagmography; D005260:Female; D006801:Humans; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000150:complications* / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology