[Effect of vitamin E an actinomycin D on protein and RNA synthesis in rat liver].
In vitro experiments showed that RNA synthesis intensity in the rat liver with E-hypovitaminosis decreases considerably while the level of the labelled precursors incorporation into protein does not differ from the norm. Under conditions of E-hypovitaminosis the inhibitory effect of actinomycin D on the RNA synthesis is pronounced more clearly as compared to the norm. In the case of the E-hypovitaminous rate liver chyme preincubation with alpha-tocopherol there is no inhibitory effect of actinomycin D on the protein biosynthesis.
D000818:Animals; D003609:Dactinomycin / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000378:metabolism*; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D013997:Time Factors; D014810:Vitamin E / Q000494:pharmacology*
D014810:Vitamin E; D003609:Dactinomycin; D012313:RNA
Biosintez belka i RNK v pecheni krys pod vozdeĭstviem vitamina E i aktinomitsina D.