Treatment of myotonic dystrophy with acetazolamide.
This report describes a patient with myotonic dystrophy who had severe action and percussion myotonia. The patient was unresponsive to diphenylhydantoin therapy. Treatment with acetazolamide, 250 mg daily, decreased the myotonia markedly. A possible mechanism of the favorable effect of acetazolamide in myotonia is discussed.
D000086:Acetazolamide / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D006801:Humans; D008297:Male; D009223:Myotonic Dystrophy / Q000097:blood / Q000188:drug therapy*; D011188:Potassium / Q000097:blood
D000086:Acetazolamide; D011188:Potassium