Prolactin and sexual behavior: a review.
Despite the large body of evidence showing that prolactin (PRL) can suppress sexual behavior in humans and rodents, it is still unclear how this hormone affects sexual capacity of male subjects. Few studies have been performed on the effects of PRL on female sexual behavior. Short-term hyperprolactinaemia seems to facilitate some elements of sexual behavior in male rats. Furthermore, contrasting finding exist on the effects of drug-induced hyperprolactinaemia on sexual capacity of male animals. The possible mechanisms of action (on peripheral organs, endocrine, central) or PRL on male behavior are discussed in details.
D000568:Amenorrhea / Q000097:blood; D000818:Animals; D014150:Antipsychotic Agents / Q000009:adverse effects; D001812:Blood-Brain Barrier; D001921:Brain / Q000502:physiology; D003307:Copulation / Q000502:physiology; D004298:Dopamine / Q000502:physiology; D007172:Erectile Dysfunction / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D010902:Pituitary Gland / Q000637:transplantation; D011388:Prolactin / Q000097:blood / Q000494:pharmacology / Q000502:physiology*; D012725:Sexual Behavior / Q000502:physiology*; D012726:Sexual Behavior, Animal / Q000187:drug effects; D012735:Sexual Dysfunction, Physiological / Q000503:physiopathology; D009435:Synaptic Transmission
D014150:Antipsychotic Agents; D011388:Prolactin; D004298:Dopamine