Capillary neoformation in skeletal muscle of dipyridamole-treated rats.
Rats were given 0.3 mg dipyridamole i.p. twice a day, 5 days/week for 3 weeks. Morphometric determinations of the hindlimb skeletal muscle of these animals showed that they had a higher degree of capillary vascular supply than the muscles of sham-injected control rats. The number of capillaries per muscle fiber was increased by 24%, the number of capillaries/mm2 by 22% and the number of capillaries in contact with each muscle fiber by 22%.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002196:Capillaries / Q000187:drug effects; D004176:Dipyridamole / Q000494:pharmacology*; D008297:Male; D009132:Muscles / Q000098:blood supply*; D009389:Neovascularization, Pathologic / Q000187:drug effects*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects
D004176:Dipyridamole