title: beta-Thromboglobulin in acute myocardial infarction.
abstract: The plasma beta-thromboglobulin level was studied serially in 14 patients with acute myocardial infarction. In 7 patients the plasma beta-thromboglobulin was initially high. The most severely affected patients had the highest values. Three patients with a mild or moderate clinical course had a normal beta-thromboglobulin level at every stage. The remaining patients had a distinct pattern in the evolution of the plasma beta-thromboglobulin values. The initial phase was followed by a uniform fall during the first days and then by an increase. The highest values were in many cases measured at discharge. Platelet counts showed a similar pattern. Signs of activation of platelets were seen before changes in coagulation and fibrinolysis.
mesh_terms: D000328:Adult; D000368:Aged; D001609:Beta-Globulins / Q000032:analysis*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D010976:Platelet Count; D011288:Prekallikrein / Q000032:analysis; D013997:Time Factors; D001620:beta-Thromboglobulin / Q000032:analysis*
chemical_list: D001609:Beta-Globulins; D005338:Fibrin Fibrinogen Degradation Products; D001620:beta-Thromboglobulin; D005169:Factor VIII; D005340:Fibrinogen; D011288:Prekallikrein