Autosensitization to DNA.
The spontaneous occurrence of widespread ecchymoses in a patient not exhibiting coagulopathy leads to a spectrum of differential diagnoses including amyloidosis, anaphylactoid purpura, pseudoxanthoma elasticum, Ehlers-Danlos syndrome, autoerythrocyte sensitization and autosensitization to DNA (11). This paper reports on a patient exhibiting the characteristic clinical findings and skin reactivity indicative of DNA autosensitization. The syndrome will be discussed briefly with particular reference to the differential diagnosis to autoerythrocyte sensitization.
D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D004247:DNA / Q000276:immunology*; D004438:Ecchymosis / Q000175:diagnosis* / Q000276:immunology; D004910:Erythrocyte Membrane / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008875:Middle Aged; D012882:Skin Tests
D004247:DNA