Aspirin and human sleep.
Two groups of 8 females were given either 3 X 600 mg aspirin or placebo daily for 4 days, double blind. With aspirin, slow wave sleep was significantly decreased and stage 2 sleep significantly increased. Aspirin also significantly disrupted intra-subject night-to-night continuity of several sleep stages during drug and recovery nights.
D000293:Adolescent; D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D004311:Double-Blind Method; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D012894:Sleep Stages / Q000187:drug effects*; D012895:Sleep, REM / Q000187:drug effects
D001241:Aspirin