beta 2-microglobulin in human tumors heterografted into athymic mice.
Beta 2-microglobulin (beta 2m) content of several human tumor lines implanted into athymic mice was investigated. The concentration of this protein was found to vary greatly from tumor to tumor. The growth rate of the tumors was inversely related to the amount of the extractable beta 2m. The fastest growing, undifferentiated tumors contained the least amount of beta 2m.
D000818:Animals; D001609:Beta-Globulins; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D005260:Female; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000032:analysis / Q000276:immunology*; D013997:Time Factors; D014183:Transplantation, Heterologous; D001613:beta 2-Microglobulin
D001609:Beta-Globulins; D001613:beta 2-Microglobulin