title: Non-blastic meningeal leukemia during the myelofibrotic phase of chronic myeloid leukemia.
abstract: Myeloblastic involvement of the central nervous system has been noted in the course of chronic myeloid leukemia in the blastic phase; meningeal leukemia in the chronic phase of CML is almost unknown. We report on a case of CML in which meningeal infiltration by cells of the granulocytes series in all stage of cellular maturation developed 15 years after initial diagnosis and seven months after a myelofibrotic transformation of the systemic disease.
mesh_terms: D000328:Adult; D002555:Cerebrospinal Fluid / Q000166:cytology*; D002904:Chromosomes, Human, 21-22 and Y; D006412:Hematopoietic Stem Cells; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D008297:Male; D008577:Meningeal Neoplasms / Q000209:etiology*; D055728:Primary Myelofibrosis / Q000209:etiology