A grading system for iris neovascularization. Prognostic implications for treatment.
A retrospective study of 34 eyes of 30 patients who had neovascularization of the anterior segment and who received panretinal photocoagulation (PRP) and/or panretinal cryotherapy was performed. The eyes were all classified preoperatively and postoperatively as to the grade of neovascularization of the iris and the anterior chamber angle according to the system devised by Weiss and Gold. The grading system of Weiss and Gold was useful in predicting the response to treatment of iris neovascularization. Almost all eyes in angle grades 0 through 2 did well. Eyes with angle grade 3 had an intermediate response. Eyes in angle grade 4 almost uniformly did poorly. Eyes with iris neovascularization secondary to central retinal vein occlusion (CRVO) or hemiretinal branch vein occlusion (HBVO) had a more rapidly progressive disease than that of eyes with rubeosis secondary to diabetes alone. The patients with the most advanced rubeosis initially, however, were those diabetics with ischemic-type CRVO.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000867:Anterior Chamber / Q000098:blood supply; D003251:Constriction, Pathologic / Q000150:complications; D003452:Cryosurgery; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007498:Iris / Q000098:blood supply*; D007499:Iris Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D011379:Prognosis; D012169:Retinal Vein; D014652:Vascular Diseases / Q000150:complications