Isolation and partial characterization of the human homologue of Thy-1.
A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy-1.
D000818:Animals; D000954:Antigens, Surface / Q000302:isolation & purification*; D002454:Cell Differentiation; D002460:Cell Line; D003429:Cross Reactions; D000939:Epitopes; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D051379:Mice; D008970:Molecular Weight; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
D000954:Antigens, Surface; D000939:Epitopes; D006023:Glycoproteins