title: Postmortem sera and cerebrospinal fluid enzymes.
abstract: Antemortem and postmortem sera from 60 dogs were evaluated for lipase, amylase, alkaline phosphatase, gamma-glutamyltransferase, and alanine aminotransferase (AAT); cerebrospinal fluid was examined for AAT and alkaline phosphatase. The postmortem intervals were 3, 6, 12, 24, and 48 h at temperatures of 4, 20, and 37 degrees C. Amylase levels remained stable at 4 and 20 degrees C and may be beneficial for diagnosing pancreatitis. Lipase levels may be useful as an adjunct to amylase values. Serum alkaline phosphatase values increased with postmortem interval; values were higher at 37 degrees C than at 4 degrees C. Other enzymes were of little value for diagnosis.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood / Q000134:cerebrospinal fluid; D000469:Alkaline Phosphatase / Q000097:blood / Q000134:cerebrospinal fluid; D000681:Amylases / Q000097:blood; D000818:Animals; D004285:Dogs; D006867:Hydrolases / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid; D008049:Lipase / Q000097:blood; D011180:Postmortem Changes; D013696:Temperature; D013997:Time Factors; D014166:Transferases / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D014166:Transferases; D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase; D006867:Hydrolases; D008049:Lipase; D000469:Alkaline Phosphatase; D000681:Amylases