WGA-HRP as a transneuronal marker in the visual pathways of monkey and rat.
Wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) was injected intraocularly in monkeys and rats. All known primary visual pathways were labeled and, in addition, ocular dominance columns in visual cortex were labeled in monkey, and in rat, parabigeminal, oculomotor, thalamic reticular, and visual cortical areas were labeled as well as neuronal soma in superior colliculus. We conclude that WGA-HRP is a useful transneuronal marker for visual pathways.
D000818:Animals; D001370:Axonal Transport; D001931:Brain Mapping / Q000379:methods*; D006735:Horseradish Peroxidase / Q000378:metabolism*; D037102:Lectins / Q000378:metabolism*; D008252:Macaca fascicularis; D008297:Male; D010544:Peroxidases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000033:anatomy & histology / Q000378:metabolism; D014795:Visual Pathways / Q000033:anatomy & histology / Q000378:metabolism*; D014909:Wheat Germ Agglutinins
D037102:Lectins; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase; D010544:Peroxidases