[Changes in the concentrations of total RNA and DNA in the cerebral cortex and internal organs (liver and heart) after prolonged hypovolemic hypotension and in the post-resuscitation period].
It was shown in experiments on dogs that after 4-hour hypovolemic hypotension the content of total RNA in brain cortex and myocardium homogenates decreased. In the liver, there was a significant decrease both in RNA and DNA content. In the postresuscitation period, the content of nucleic acids in the myocardium returned to normal after 14--21 days, and that in the liver after 3--4 months. The gray matter of the brain manifested a delayed lowering of DNA content (after 14--21 days), and the level of nucleic acid did not return ot normal over 3--4 months after resuscitation.
D000818:Animals; D001810:Blood Volume; D002540:Cerebral Cortex / Q000032:analysis*; D004247:DNA / Q000032:analysis*; D003643:Death; D004285:Dogs; D005260:Female; D006470:Hemorrhage / Q000378:metabolism*; D007022:Hypotension / Q000378:metabolism*; D008099:Liver / Q000032:analysis; D008297:Male; D009206:Myocardium / Q000032:analysis; D009928:Organ Specificity; D012313:RNA / Q000032:analysis*; D012151:Resuscitation
D012313:RNA; D004247:DNA
Osobennosti izmeneniia soderzhaniia obshcheĭ RNK i DNK v kore golovnogo mozga i vnutrennikh organakh (pechen' i serdtse) posle dlitel'noĭ gipovolemicheskoĭ gipotenzii i v postreanimatsionnoĭ period.