Gc revisited: six further Gc-phenotypes delineated by isoelectric focusing and by polyacrylamide gel electrophoresis.
Six newly observed Gc variants are described. The variants Gc 1A10, 1A11, 1A12, 1A13, and 1C11 have double band patterns. The anodal bands of these variants are susceptible to neuraminidase treatment. Gc 2A7 is a single band variant which is not altered by neuraminidase incubation. Polyacrylamide gel isoelectrofocusing with immunofixation and polyarcylamide gel electrophoresis appear to be efficient methods for the analysis of the Gc system.
D000510:Alpha-Globulins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D010641:Phenotype; D014807:Vitamin D / Q000235:genetics* / Q000378:metabolism; D014809:Vitamin D-Binding Protein
D000510:Alpha-Globulins; D002352:Carrier Proteins; D014809:Vitamin D-Binding Protein; D014807:Vitamin D