Immunological mechanisms in the maintenance of pregnancy.
Mmammalian pregnancy involves prolonged, intimate interactions between genetically dissimilar organisms. This dissimilarity evokes an immunological response in the gravida which promotes placental implantation and fetal viability. The nature of the immunological reactions, the factors moderating these responses and the signficance of abnormalities in the responses are discussed.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D005938:Glucocorticoids / Q000494:pharmacology; D006801:Humans; D007074:Immunoglobulin G; D007165:Immunosuppression Therapy; D008264:Macrophages / Q000276:immunology; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000276:immunology; D010928:Placental Lactogen / Q000494:pharmacology; D011247:Pregnancy; D011255:Pregnancy Maintenance; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D014599:Uterus / Q000276:immunology; D000509:alpha-Fetoproteins / Q000494:pharmacology
D006063:Chorionic Gonadotropin; D004967:Estrogens; D005938:Glucocorticoids; D007074:Immunoglobulin G; D000509:alpha-Fetoproteins; D011374:Progesterone; D010928:Placental Lactogen