[Effect of exogenic thyroid RNA on cultured fragments of the dog thyroid].
Radioactive iodine accumulation, protein and RNA synthesis by organic cultures of the dog thyroid gland after addition of exogenic thyroid RNA to the medium were studied. It was established that thyrotropin-induced exogenic RNA stimulates radioactive iodine accumulation as well as protein and RNA synthesis. The role of the thyrocyte genetic apparatus in throtropin mode of action is discussed.
D000818:Animals; D003470:Culture Media; D004285:Dogs; D006728:Hormones / Q000494:pharmacology; D007457:Iodine Radioisotopes; D007553:Isotope Labeling; D009924:Organ Culture Techniques; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism*; D013972:Thyrotropin / Q000494:pharmacology
D003470:Culture Media; D006728:Hormones; D007457:Iodine Radioisotopes; D012313:RNA; D013972:Thyrotropin
Deistvie eksogennykh tireoidnykh RNK na kul'tiviruemye fragmenty shchitovidnykh zhelez sobak.