title: Short-term intensive cyclophosphamide treatment in multiple sclerosis. A retrospective controlled study.
abstract: The effect of short-term intensive cyclophosphamide therapy upon 21 patients with moderately advanced multiple sclerosis is compared with a non-treated control group of 21 patients retrospectively matched for global disability. The progression of the disease was evaluated by regular disability scoring, and the results were analyzed by non-parametric statistical tests. No significant differences in the progression of the disability could be detected during a follow-up period of 2 years.
mesh_terms: D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy*; D012189:Retrospective Studies
chemical_list: D003520:Cyclophosphamide