Studies on kidney function in subjects exposed to organic solvents. I. Excretion of albumin and beta-2-microglobulin in the urine.
The urine of 134 subjects, exposed to different organic solvents, and 48 unexposed subjects has been analysed with reference to albumin and beta-2-microglobulin excretion. The exposed subjects excreted significantly larger quantities of albumin than the unexposed. Those exposed to styrene excreted the largest amounts. No significant difference in beta-microglobulin excretion could be demonstrated between the groups.
D000328:Adult; D000419:Albuminuria; D001609:Beta-Globulins / Q000652:urine*; D004781:Environmental Exposure; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D012997:Solvents / Q000009:adverse effects*; D013343:Styrenes / Q000009:adverse effects; D014050:Toluene / Q000009:adverse effects; D014992:Xylenes / Q000009:adverse effects; D001613:beta 2-Microglobulin / Q000652:urine*
D001609:Beta-Globulins; D012997:Solvents; D013343:Styrenes; D014992:Xylenes; D001613:beta 2-Microglobulin; D014050:Toluene