title: [Pathogenetic treatment of acute pancreatitis].
abstract: In acute experiments in albino rats it was shown that mannitol, polyglucin and hemodesis possess antiproteolytic properties. Pyridoxine, hemodesis and polyglucin were also found to be antagonists to the effects of bradykinin. Pyridoxine, polyglucin and hemodesis proved to be most effective in the treatment of experimental trypsinemia. The results of the conservative treatment of patients with acute pancreatitis were better if pyridoxine and polyglucin were added to the complex of curative measures.
mesh_terms: D000208:Acute Disease; D000818:Animals; D007611:Aprotinin / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D003911:Dextrans / Q000008:administration & dosage*; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000188:drug therapy* / Q000209:etiology; D011736:Pyridoxine / Q000008:administration & dosage*; D051381:Rats; D014357:Trypsin / Q000378:metabolism
chemical_list: D003911:Dextrans; D007611:Aprotinin; D014357:Trypsin; D011736:Pyridoxine
vernacular_title: O patogeneticheskom lechenii ostrogo pankreatita.