Three-dimensional structure of Escherichia coli initiator tRNAfMet.
The crystal structure of Escherichia coli tRNAfMet an initiator transfer RNA, has been determined. While grossly similar to that of the chain-elongating yeast tRNAPhe, there are three major differences. One involves the folding of the anticodon loop; in particular, the position of the constant uridine, U33. This difference was unexpected and may be of functional significance.
D000926:Anticodon; D004926:Escherichia coli; D008715:Methionine; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010442:Peptide Chain Initiation, Translational; D012329:RNA, Bacterial; D012343:RNA, Transfer; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
D000926:Anticodon; D012329:RNA, Bacterial; D012343:RNA, Transfer; D008715:Methionine