Epidermal origin of the amyloid in localized cutaneous amyloidosis.
A case of localized cutaneous amyloidosis which developed after a lichen planus-like skin reaction is reported. The amyloid consisted of amyloid fibrils enveloped by heparan sulphate granules. These amyloid fibrils reacted to anti-human keratin antibody, indicating an epidermal origin for the fibrils.
D000368:Aged; D000682:Amyloid / Q000032:analysis* / Q000276:immunology; D000686:Amyloidosis / Q000378:metabolism*; D000906:Antibodies / Q000276:immunology; D006497:Heparan Sulfate / Q000032:analysis; D006801:Humans; D007633:Keratins / Q000276:immunology; D008297:Male; D012867:Skin / Q000378:metabolism; D012871:Skin Diseases / Q000378:metabolism*
D000682:Amyloid; D000906:Antibodies; D006497:Heparan Sulfate; D007633:Keratins