Amino acid sequence of a human leukocyte interferon.
The primary structures of three major species of human leukocyte interferon differ from the structure predicted from the DNA sequence of recombinants containing leukocyte interferon-coding regions. Compared to the recombinant interferon produced in bacteria, three of the purified natural proteins isolated from leukocytes lack the 10 COOH-terminal amino acids suggested by the DNA sequence.
D000595:Amino Acid Sequence; D002478:Cells, Cultured; D004274:DNA, Recombinant / Q000378:metabolism; D006801:Humans; D007372:Interferons / Q000235:genetics; D007951:Leukemia, Myeloid / Q000503:physiopathology; D007962:Leukocytes / Q000032:analysis*; D010446:Peptide Fragments / Q000032:analysis
D004274:DNA, Recombinant; D010446:Peptide Fragments; D007372:Interferons