title: "The choledocho-pancreatic long common channel disorders" in relation to the etiology of congenital biliary dilatation and other biliary tract disease.
abstract: The amylase level of bile and various cholangiograms was studied in 36 cases of congenital biliary dilatation. (C.B.D.) The amylase level above 10000 U/L was considered to suggest the existence of choledocho-pancreatic long common channel formation. Radiologically, the dilatation of intrahepatic bile duct was seen in 9 out of 19 (47%) Type I cases and in all (100%) Type II cases. The cystic dilatation of intrahepatic bile duct was seen in all Type I cases which have cystic choledochal dilatation. On the other hand, fusiform dilatation was seen in all Type II cases with fusiform choledochal dilatation. End to side Choledocho-pancreatic anastomosis was performed to produce an experimental model of human choledocho-pancreatic long common channel disorders, thus leading to the dilatation of the common bile duct as well as the reflux of pancreatic juice into the bile duct. The reflux of Pancreatic juice and congenital stricture due to the choledocho-pancreatic long common channel formation were considered to be the important causative factors in the etiology of C.B.D.. Furthermore, pathology of the choledocho-pancreatic long common channel disorders was found to be important in relation to the etiology of both C.B.D. and other lesions of the biliary tract and pancreas.
mesh_terms: D000293:Adolescent; D000328:Adult; D000681:Amylases / Q000378:metabolism; D001646:Bile / Q000201:enzymology; D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities*; D001660:Biliary Tract Diseases / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D003135:Common Bile Duct / Q000002:abnormalities; D003137:Common Bile Duct Diseases / Q000209:etiology*; D003560:Cysts / Q000209:etiology*; D004108:Dilatation, Pathologic / Q000151:congenital; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010183:Pancreatic Ducts / Q000002:abnormalities; D010189:Pancreatic Juice / Q000502:physiology
chemical_list: D000681:Amylases