Inhibitory effect of novobiocin on ribonucleic acid synthesis during germination of Bacillus subtilis spores.
Novobiocin inhibited ribonculeic acid synthesis during germination of Bacillus subtilis spores. Transcription of certain kinds of genes probably required a preceding conformational change in deoxyribonucleic acid.
D001412:Bacillus subtilis / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D004269:DNA, Bacterial / Q000096:biosynthesis; D009675:Novobiocin / Q000494:pharmacology*; D012329:RNA, Bacterial / Q000096:biosynthesis*; D013171:Spores, Bacterial / Q000502:physiology; D013997:Time Factors
D004269:DNA, Bacterial; D012329:RNA, Bacterial; D009675:Novobiocin