title: [In vitro dentinogenesis of mice fetuses tooth germs in the presence of fluoride. Morphological nad historical observations].
abstract: Observations show that fluoride alters dentinogenesis in vitro. Morphological and cellular alterations are greater when the tooth germs are young and/or when the time of incubation is longer and the dose of fluoride higher. In the predentine, the stainability of proteoglycans is partially reduced. The persistence of alcianophilic zones far from the site of secretion indicates some delay of the process of matricial maturation.
mesh_terms: D000818:Animals; D003810:Dentinogenesis; D005260:Female; D005333:Fetus; D051379:Mice; D011247:Pregnancy; D011509:Proteoglycans / Q000032:analysis; D013194:Staining and Labeling; D014083:Tooth Germ / Q000166:cytology / Q000196:embryology*
chemical_list: D011509:Proteoglycans
vernacular_title: Etude de la dentinogenèse de germes dentaires de faetus de souris cultivés in vitro en présence de fluor. Observations morphologiques et histochimiques.