title: [Study of left ventricular function using systolic time intervals in a group of patients with polycythemia vera (Vaquez-Osler disease)].
abstract: Left ventricular performance has been studied in 50 patients affected by primary polycythemia (P.V.) by determining systolic time intervals. 50 normal subjects were used as control group. All cases underwent a pharmacodynamic test with Amyl Nitrite. The results indicate that patients with P.V. present an abnormal behaviour of left ventricular performance after Amyl Nitrite; this alteration is more evident in patients with arterial hypertension. Amyl Nitrite, through its pharmacological action, causes changes in systolic time intervals and reveals a state of latent cardiac failure.
mesh_terms: D000328:Adult; D000368:Aged; D000680:Amyl Nitrite; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D011087:Polycythemia Vera / Q000503:physiopathology*; D013599:Systole
chemical_list: D000680:Amyl Nitrite
vernacular_title: Lo studio della funzione del ventricolo sinistro mediante l'uso dei tempi sistolici in un gruppo di pazienti affetti da policitemia vera (morbo di Vaquez-Osler).