title: Leukonychia partialis. A phase of leukonychia totalis.
abstract: Accumulated evidence indicates that leukonychia striata and leukonychia totalis are distinct entities transmitted by automonal dominant gene. Much less secure is the status of leukonychia partialis in which the nail is white proximally and pink near its free edge. Leukonychia totalis and leukonychia partialis have occurred in different members of the same family and on different digits of an individual simultaneously, and either has presented as the clinical manifestation in an individual at different times. The two conditions are probably expressions of the same genetic defect. Historically, the term leukonychia totalis has priority over leukonychia partialis and the former form should be used, with the latter considered a variation of it.
mesh_terms: D003116:Color; D005260:Female; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000145:classification* / Q000235:genetics
chemical_list: D007633:Keratins