Precipitin system detected in sera from patients with non-A, non-B hepatitis.
A precipitin system detected by immunodiffusion was identified using sera from patients with non-A, non-B hepatitis. This system resembled those described by other authors as serological tests for non-A, non-B antigens and antibodies. However, testing of sera from a large number of patients with acute and chronic liver diseases revealed that this precipitin system was not specific for non-A, non-B hepatitis. Further characterization of the precipitin system demonstrated that it did not represent a true antigen-antibody reaction. Precipitin lines detected by immunodiffusion during the course of acute and chronic non-A, non-B hepatitis may no represent reactions specific for this disease.
D000937:Antigen-Antibody Reactions; D002850:Chromatography, Gel; D000939:Epitopes; D006526:Hepatitis C / Q000276:immunology*; D006525:Hepatitis, Viral, Human / Q000276:immunology*; D006801:Humans; D005779:Immunodiffusion; D011234:Precipitins / Q000032:analysis* / Q000276:immunology
D000939:Epitopes; D011234:Precipitins