title: [Asymmetric histogram of nucleolar nucleic acid concentration as a potential index of ribosomal DNA amplification in rabbit cerebellar Purkinje cells].
abstract: Purkinje's cells from the rat cerebellum were exposed to UV cytophotometry in order to evaluate the nucleic acid content in the nucleoli and perinucleolar chromatin. The study revealed an asymmetrical histogram of RNA distribution in the Purkinje's cell nucleoli. The cells with an increased RNA content in the nucleolus displayed the elevated quantities of nucleic acids in the perinuclear chromatin. A relationship of the phenomenon under study and the hypothesis of ribosomal DNA amplification in Purkinje's cells is discussed.
mesh_terms: D000818:Animals; D002466:Cell Nucleolus / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D005784:Gene Amplification; D006651:Histocytochemistry; D008297:Male; D010783:Photometry; D011689:Purkinje Cells / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D051381:Rats
chemical_list: D002843:Chromatin; D012313:RNA; D004247:DNA
vernacular_title: Nesimmetrichnaia gistogramma soderzhaniia iadryshkovykh nukleinovykh kislot kak vozmozhnyĭ pokazatel' amplifikatsii ribosomnoĭ DNK v kletkakh Purkin'e mozzhechka krysy.