Agglutinating phenomenon in the rat sera after administration of methylcellulose.
In the serum of Wistar rats following intraperitoneal application of methylcellulose (Kabi) the presence of the aggregation factor was confirmed. Using the more sensitive immunohaematological method-enzyme tests-we proved the agglutination phenomenon, which can be of antibody nature and cannot be induced under the test conditions in vitro by action of methylcellulose on blood cells and serum of normal rats. The described phenomenon will only occur if methylcellulose "passes" the organism of the experimental animal.
D000818:Animals; D004912:Erythrocytes / Q000276:immunology; D005361:Ficain; D006384:Hemagglutination / Q000187:drug effects*; D008297:Male; D008747:Methylcellulose / Q000494:pharmacology*; D051381:Rats; D014357:Trypsin
D008747:Methylcellulose; D014357:Trypsin; D005361:Ficain