[Macrophage "disappearance" from the peritoneal cavity as affected by a specific antigen].
Investigations were carried out into the effect of a specific antigen on the changes in the macrophage count in the peritoneal exudate of guinea pigs sensibilized with a live Salmonella abortus ovis culture, with and without an allergic reaction of a delayed type. The setting in of the allergic response was shown to correlate with the decrease in the number of macrophages--in animals with a positive response there was a strong drop of the macrophage count in the peritoneal exudate. It is stated that the changes observed in the number of these cells are directly associated with the dose used: they are more strongly manifested when larger amounts of the S. abortus ovis antigen are used.
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001202:Ascitic Fluid / Q000166:cytology / Q000276:immunology*; D002452:Cell Count; D004306:Dose-Response Relationship, Immunologic; D000939:Epitopes / Q000276:immunology*; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007114:Immunization; D008264:Macrophages / Q000276:immunology*; D012475:Salmonella / Q000276:immunology*; D012882:Skin Tests
D000942:Antigens, Bacterial; D000939:Epitopes
"Izchezvane" na makrofagite ot peritonealnata praznina pod vliianie na spetsifichen antigen.