title: Further studies on antigen variation in Staphylococcus aureus.
abstract: The plating of successive Staphylococcus aureus subcultures of daily transfers proved that discontinuous variation resembling a genetic mutation and selective outgrowth of the variant are responsible for antigen variation. Every subculture of S. aureus, when repeatedly transferred, contained a mixture of cells with original antigen 17 (or 13) and final antigen 1 (or 3) that are relevant for research, serological diagnosis, and epidemiological study of staphylococcal diseases.
mesh_terms: D000942:Antigens, Bacterial; D000939:Epitopes; D014644:Genetic Variation; D009154:Mutation; D013211:Staphylococcus aureus / Q000235:genetics / Q000254:growth & development / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D000939:Epitopes