title: Immunoglobulin-bearing cells in the liver biopsies from patients with psoriasis.
abstract: Sections of liver tissue from 41 patients with psoriasis were examined histologically and by immunofluorescence microscopy to detect cells bearing the immunoglobulins IgG, IgA or IgM. Two patients with non-specific, reactive hepatitis and two with cirrhosis had more numerous immunoglobulin-bearing cells, while no correlation was found between the number of immunoglobulin-bearing cells and 1) other types of abnormal liver histology, 2) lymphocytic infiltrates in the liver, or 3) methotrexate therapy.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D008727:Methotrexate / Q000009:adverse effects; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D011565:Psoriasis / Q000150:complications / Q000276:immunology*
chemical_list: D007136:Immunoglobulins; D008727:Methotrexate