title: Further observations on sleep abnormalities in Kleine-Levin syndrome: abnormal breathing pattern during sleep.
abstract: In two adolescent and two adult patients with Kleine-Levin syndrome, polygraphic sleep recording performed during somnolent and non-somnolent periods revealed various forms of abnormal breathing patterns during sleep. These included periodic breathing and hypopnoeic episodes associated with brief arousals and, in one adult patient, a full blown sleep apnoea syndrome. It is suggested that abnormal breathing in sleep in this syndrome may result from central hypoexcitability.
mesh_terms: D000293:Adolescent; D000328:Adult; D006970:Disorders of Excessive Somnolence / Q000209:etiology* / Q000503:physiopathology; D004569:Electroencephalography; D004576:Electromyography; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications; D008875:Middle Aged; D012120:Respiration Disorders / Q000209:etiology*; D012725:Sexual Behavior; D012893:Sleep Wake Disorders / Q000209:etiology*; D013577:Syndrome