Dihydrostreptomycin toxicity in the Mongolian gerbil, Meriones unguiculatus.
A fatal syndrome of acute toxicity was produced in Mongolian gerbils following the injection of a penicillin-dihydrostreptomycin-procaine combination. The toxicity was determined to be due to the dihydrostreptomycin component. Fifty milligrams of dihydrostreptomycin produced 80-100% mortality in 55-65 g gerbils.
D000818:Animals; D004096:Dihydrostreptomycin Sulfate / Q000633:toxicity*; D005260:Female; D005849:Gerbillinae; D008297:Male; D010243:Paralysis / Q000139:chemically induced / Q000662:veterinary; D010402:Penicillin G Procaine / Q000633:toxicity; D011343:Procaine / Q000633:toxicity; D012376:Rodent Diseases / Q000139:chemically induced*
D010402:Penicillin G Procaine; D011343:Procaine; D004096:Dihydrostreptomycin Sulfate