[Comparative blood coagulation studies in PGF2a- and 15-methyl-PGF2a-induced therapeutic abortion].
In 15 pregnant women of the first trimenon of gravidity an interruption was performed by means of extra-amnial application of PGF2a and in 10 pregnant women by means of i. m. application of 15-methyl-PGF2a. Bleeding time, recalcification time, number of thrombocytes, heat fibrin, and thrombocyte adhesiveness were determined before, during and after treatment. Statistically significant changes could be observed during bleeding time, heat fibrin, and thrombocyte number. The investigations of coagulation, however, did not reveal any considerable impairment of the coagulation system, thus confirming the positive evaluation of prostaglandines used for therapeutic induction of abortion.
D000032:Abortion, Therapeutic / Q000379:methods*; D001760:Bleeding Time; D001777:Blood Coagulation / Q000187:drug effects*; D002260:Carboprost / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D010973:Platelet Adhesiveness; D010976:Platelet Count; D011247:Pregnancy; D011460:Prostaglandins F / Q000008:administration & dosage / Q000494:pharmacology*; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*
D011460:Prostaglandins F; D011461:Prostaglandins F, Synthetic; D002260:Carboprost
Vergleichende Gerinnungsuntersuchungen bei PGF2a- und 15-Methyl-PGF2a-induzierten therapeutischen Abortus.