title: A familial polymorphic variant of chromosome 5.
abstract: Two male fetuses and their mothers, referred for amniocentesis because of high levels of AFP in their blood, were found to carry an anomalous chromosome 5 with a large heterochromatic segment in the long arm. One of the fetuses had an additional ring chromosome.
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000032:analysis; D000782:Aneuploidy; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002905:Chromosomes, Human, 4-5 / Q000648:ultrastructure*; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D011296:Prenatal Diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins