[Connections between the mast cell system of a focus of inflammation and the zona fasciculata of the adrenal cortex].
At aseptic inflammation developing around a solid foreign body and proceeding both under common conditions and on the background of disturbed inactivation of free amines as a result of monoaminoxidase blockade with vetrasin or devastation of amine tissue depots with reserpine it has been stated that indices of the adrenal cortex activity (hyperemia, contents of ascorbic acid and corticoids) and those of the mast cells system in the inflammatory focus (amount of the cells, their size, contents of glycosaminoglycans, RNA, tryptophan and histidine) are subjected to certain fluctuations during inflammation. Increasing activity of the adrenal cortex fascicular zone and renewal of the mast cell population in the inflammatory focus are directly proportional to the degree of a disturbed deposition of free amines in the organism. Certain positive correlations prevail in cooperation of the adrenal cortex activity, decomposition rate of large (mature) mast cells and migration into the inflammatory focus of small (immature) forms of these cells.
D000302:Adrenal Cortex / Q000098:blood supply / Q000503:physiopathology*; D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D002452:Cell Count; D006025:Glycosaminoglycans / Q000378:metabolism; D007249:Inflammation / Q000503:physiopathology*; D008297:Male; D008407:Mast Cells / Q000502:physiology*; D008995:Monoamine Oxidase / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D051381:Rats
D000305:Adrenal Cortex Hormones; D006025:Glycosaminoglycans; D012313:RNA; D008995:Monoamine Oxidase; D001205:Ascorbic Acid
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