title: Interaction of targeted liposomes with human peripheral mononuclear blood cells and lymphocytes of chronic lymphoid leukaemic patients.
abstract: Association of small unilamellar vesicles (SUV) can be effectively targeted to normal human peripheral mononuclear blood cells (PMBC). - Lymphocytes of chronic lymphoid leukaemic (CLL) patients show a low rate of liposome association, which cannot be improved by targeting with anti-lymphocyte globulin (ALG). Presence of serum evoked an enhanced association of liposomes to PMBC.
mesh_terms: D000818:Animals; D000961:Antilymphocyte Serum; D006801:Humans; D007074:Immunoglobulin G; D007945:Leukemia, Lymphoid / Q000097:blood*; D008081:Liposomes; D008214:Lymphocytes / Q000502:physiology*; D009000:Monocytes / Q000502:physiology*; D009439:Neuraminidase / Q000494:pharmacology; D011402:Pronase / Q000494:pharmacology; D011817:Rabbits; D000511:alpha-Macroglobulins
chemical_list: D000961:Antilymphocyte Serum; D007074:Immunoglobulin G; D008081:Liposomes; D000511:alpha-Macroglobulins; D009439:Neuraminidase; D011402:Pronase