Chronic arthritis in goats caused by a retrovirus.
A virus was isolated from an adult goat with chronic arthritis and shown to belong to the retrovirus group by electron microscopy and biochemical methods. Inoculation of the virus into cesarean-derived specific-pathogen-free goats' kids produced arthritic lesions similar to those in the spontaneous disease. Vrus was reisolated from the experimentally induced lesions.
D000818:Animals; D001170:Arthritis, Infectious / Q000382:microbiology / Q000662:veterinary*; D004679:Encephalomyelitis / Q000382:microbiology / Q000662:veterinary*; D006041:Goats / Q000382:microbiology*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D012190:Retroviridae / Q000648:ultrastructure; D014777:Virus Diseases / Q000150:complications / Q000635:transmission / Q000662:veterinary*
D012194:RNA-Directed DNA Polymerase