title: Differential breakdown of phylogenetically diverse ribosomal RNA's inserted via liposomes into mammalian cells.
abstract: Liposomes were used to deliver ribosomal RNA's from the different organisms into cultivated mouse plasmacytoma cells. Ribosomal RNA from Escherichia coli was degraded intracellularly within 1 hour, whereas mouse and yeast ribosomal RNA's were degraded more slowly. This indicates that cells can discriminated between different ribosomal RNA's.
mesh_terms: D000818:Animals; D002460:Cell Line; D004926:Escherichia coli; D007700:Kinetics; D008081:Liposomes; D051379:Mice; D008970:Molecular Weight; D009374:Neoplasms, Experimental / Q000378:metabolism; D010954:Plasmacytoma / Q000378:metabolism*; D012329:RNA, Bacterial / Q000378:metabolism; D012335:RNA, Ribosomal / Q000378:metabolism*; D012441:Saccharomyces cerevisiae; D013045:Species Specificity
chemical_list: D008081:Liposomes; D012329:RNA, Bacterial; D012335:RNA, Ribosomal