title: Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002469:Cell Separation; D002474:Cell-Free System; D004247:DNA / Q000378:metabolism; D004274:DNA, Recombinant; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D005947:Glucose / Q000494:pharmacology; D007328:Insulin / Q000096:biosynthesis; D007515:Islets of Langerhans / Q000378:metabolism*; D007737:Kynurenine / Q000494:pharmacology; D008970:Molecular Weight; D009243:NAD / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D011384:Proinsulin / Q000096:biosynthesis* / Q000235:genetics; D014176:Protein Biosynthesis / Q000187:drug effects; D012313:RNA / Q000096:biosynthesis; D012333:RNA, Messenger / Q000302:isolation & purification; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D004274:DNA, Recombinant; D007328:Insulin; D012333:RNA, Messenger; D009243:NAD; D007737:Kynurenine; D012313:RNA; D004247:DNA; D011384:Proinsulin; D011065:Poly(ADP-ribose) Polymerases; D005947:Glucose