Medial histocompatibility antigens.
Medial histocompatibility (H) antigens are weak H antigens, recognized by unrestricted T cells; they differ thus from both major and minor H antigens. An example, Qed-1, is described in detail, and other known medial H antigens of the mouse are reviewed. The structural and genetic relationships of major and medial H antigens and their role in T cell recognition are discussed.
D000818:Animals; D000955:Antigens, T-Independent / Q000235:genetics*; D000939:Epitopes / Q000235:genetics; D005796:Genes; D008040:Genetic Linkage; D006084:Graft Rejection; D006183:H-2 Antigens / Q000235:genetics; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006801:Humans; D008285:Major Histocompatibility Complex; D051379:Mice; D051381:Rats; D016038:Skin Transplantation; D013601:T-Lymphocytes / Q000276:immunology*; D014018:Tissue Distribution
D000955:Antigens, T-Independent; D000939:Epitopes; D006183:H-2 Antigens; D000949:Histocompatibility Antigens Class II