title: Regulation of membrane phospholipid syntheesis in Escherichia coli during temperature up-shift.
abstract: The synthesis of membrane phospholipids and that of stable ribonucleic acid were inhibited during temperature up-shift of both rel+ and relA strains of Escherichia coli. The kinetics of the inhibition of the synthesis of both molecules were correlated with the kinetics of guanosine 5'-diphosphate-3'-diphosphate synthesis. Metabolic down-shift experiments gave similar results.
mesh_terms: D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D006159:Guanosine Tetraphosphate / Q000096:biosynthesis; D007700:Kinetics; D008563:Membrane Lipids / Q000096:biosynthesis*; D009154:Mutation; D010743:Phospholipids / Q000096:biosynthesis*; D012329:RNA, Bacterial / Q000096:biosynthesis; D013386:Succinates / Q000378:metabolism; D013696:Temperature
chemical_list: D008563:Membrane Lipids; D010743:Phospholipids; D012329:RNA, Bacterial; D013386:Succinates; D006159:Guanosine Tetraphosphate