Determining antigenic relationships on the basis of MLC testing. I. A matrix approach for listing all possible antigenic assignments.
We present an approach for determining all possible antigenic relationships among a group of individuals, on the basis of MLC results. We assume that the researcher or tissue typer has a criterion for classifying responses into positives and negatives, and that this classification has already been done for the data set being considered. Given any set of positive and negative MLC responses, our technique produces all antigenic assignments consistent with the assumption that a response occurs if and only if the stimulator has antigen(s) foreign to the responder. No genetic assumptions are made.
D000941:Antigens; D000939:Epitopes; D000949:Histocompatibility Antigens Class II; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008433:Mathematics
D000941:Antigens; D000939:Epitopes; D000949:Histocompatibility Antigens Class II