Secretion rate of intestinal immunoglobulins, complement factor C3, "acute phase" reactants, and albumin in the perfused ileum and jejunum of normal man.
A new method for assessment of the intestinal secretion rate of immunoglobulins and other proteins is evaluated. The procedure involves a combination of luminal perfusion of a defined intestinal segment and analysis of the aspirated perfusates by rocket immunoelectrophoresis. The technique is sensitive and reliable. A material from the normal human jejunum and ileum is presented. The method is proposed as an investigative tool for characterization of the local immunological system of the small intestine.
D000328:Adult; D000510:Alpha-Globulins / Q000378:metabolism; D003176:Complement C3 / Q000378:metabolism*; D005260:Female; D006801:Humans; D007082:Ileum / Q000276:immunology; D007122:Immunoelectrophoresis; D007136:Immunoglobulins / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000276:immunology* / Q000378:metabolism; D007421:Intestine, Small / Q000276:immunology*; D007583:Jejunum / Q000276:immunology; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D012709:Serum Albumin / Q000378:metabolism
D000510:Alpha-Globulins; D003176:Complement C3; D007136:Immunoglobulins; D012709:Serum Albumin