Increased plasma histamine levels in migraine patients.
Whole blood and plasma histamine levels, peripheral basophil and eosinophil counts and serum immunoglobulins have been measured in a group of eighteen patients with migraine in remission and in twelve of these patients during a headache attack. Plasma histamine levels were significantly elevated (P less than 0.0005) in patients with migraine both during headache attacks and symptom-free periods.
D000328:Adult; D001491:Basophils; D004804:Eosinophils; D005260:Female; D006632:Histamine / Q000097:blood*; D006636:Histamine Release; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis; D007073:Immunoglobulin E / Q000096:biosynthesis; D007958:Leukocyte Count; D008297:Male; D008407:Mast Cells / Q000378:metabolism; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood* / Q000150:complications / Q000276:immunology; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications
D007070:Immunoglobulin A; D007073:Immunoglobulin E; D006632:Histamine