Five families with homozygous delta-thalassaemia in Japan.
Five families with delta-thalassaemia discovered in Ehime, Japan, are presented. The delta-thalassaemia was associated with a slight elevation of the level of Hb F in two families and with normal Hb F levels in three. Complete absence of HbA2 was found in the homozygous probands. No abnormal clinical or haematological findings were noted in the individuals with delta-thalassaemia.
D000328:Adult; D000368:Aged; D004592:Electrophoresis, Starch Gel; D005260:Female; D005319:Fetal Hemoglobin / Q000032:analysis; D006443:Hemoglobin A2 / Q000032:analysis; D006720:Homozygote; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013789:Thalassemia / Q000097:blood / Q000235:genetics*
D006443:Hemoglobin A2; D005319:Fetal Hemoglobin