The effect of cortisol on stimulation of enzymatic activity and absorption of amino acids in the small intestine of adult hamsters.
The s.c. administration of cortisol to hamsters (50 mg/kg body wt/day for 4 days) produces a significant increase in maltase sucrase, alkaline phosphatase and leucineaminopeptidase activity in intestinal mucosa. Lactase activity is unaffected by cortisol. Gamma-glutamyltranspeptidase activity increases slightly in females but remains unchanged in males. Cortisol causes increase in proline and glycine absorption without changing the absorption of lysine.
D000469:Alkaline Phosphatase / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D006224:Cricetinae; D005260:Female; D006854:Hydrocortisone / Q000494:pharmacology*; D006867:Hydrolases / Q000378:metabolism*; D007408:Intestinal Absorption / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000201:enzymology; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism*; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008297:Male; D013393:Sucrase / Q000378:metabolism; D000520:alpha-Glucosidases / Q000378:metabolism; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D000596:Amino Acids; D005723:gamma-Glutamyltransferase; D006867:Hydrolases; D000469:Alkaline Phosphatase; D000520:alpha-Glucosidases; D013393:Sucrase; D007931:Leucyl Aminopeptidase; D006854:Hydrocortisone