Ontogeny and distribution of alpha-fetoprotein in feto-neonatal rat brain.
Maximal level of alpha-fetoprotein (AFP) recorded in fetal rat brain on day 18 of gestation declined progressively with development to low level at day 7 after parturition. Different regions of brain contained AFP in the following order: olfactory greater than cerebrum greater than cerebellum, remaining portion. Developmental profiles of AFP in discrete regions of feto-neonatal rat brain were similar and reflected the ontogeny of the protein in whole brain.
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000378:metabolism*; D005260:Female; D005865:Gestational Age; D009474:Neurons / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins