Immunohistochemical localisation of keratin in human lung tumours.
Antisera against total keratin extracts of human callus have been used to identify keratins in lung tumours of different histological type. Forty-three were classified by the WHO scheme. Keratin immunoreactive cells were identified in all 8 epidermoid carcinomas; 6 out of 12 large cell carcinomas; 2 out of 6 adenocarcinomas; 2 out of 15 small cell carcinomas and in the only muco-epidermoid carcinoma. These cases demonstrate the heterogeneity of phenotypic expression in lung tumours not recognisable without the use of immunohistochemical techniques.
D000230:Adenocarcinoma / Q000032:analysis; D001984:Bronchial Neoplasms / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis; D018288:Carcinoma, Small Cell / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000032:analysis; D006801:Humans; D007106:Immune Sera; D007633:Keratins / Q000032:analysis*; D008175:Lung Neoplasms / Q000032:analysis*; D010641:Phenotype
D007106:Immune Sera; D007633:Keratins