[Beta-2-microglobulin and rheumatoid factor levels in the synovial fluid (author's transl)].
The object of this study was to determine whether levels of beta-2-microglobulin and of rheumatoid factor measured by an enzyme-immunoassay allowed good discrimination between inflammatory and degenerative arthropathies. A multiparametric study of synovial fluid was performed on 85 specimens from patients with rheumatoid arthritis, chondrocalcinosis, mechanical arthritis and traumatic arthopathies. A beta-2-microglobulin level of less than 4 mg/l is a result very mich in favor of a non-inflammatory arthropathy (48/49 cases). The quantification of intra-articular rheumatoid factor allows for reclassification in the context of sero-negative rheumatoid arthritis.
D001172:Arthritis, Rheumatoid / Q000378:metabolism; D001609:Beta-Globulins / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D011863:Radioimmunoassay / Q000379:methods; D012217:Rheumatoid Factor / Q000032:analysis*; D013582:Synovial Fluid / Q000032:analysis*; D001613:beta 2-Microglobulin / Q000032:analysis*
D001609:Beta-Globulins; D001613:beta 2-Microglobulin; D012217:Rheumatoid Factor
Bêta-2-microglobuline et facteur rhumatoïde dans le liquide synovial. 85 dosages.