[Production of human type I interferon by lymphocytes in contact with cells infected by herpesvirus and fixed with glutaraldehyde].
Type I interferon was released from human lymphocytes cultured on cells infected with Herpesvirus and fixed with glutaraldehyde. This process of interferon induction did not involve histocompatibility antigens nor the Herpes immunity of the lymphocyte donors. Type I interferon can also be induced after interaction between lymphocytes and other intranuclear replicating virus infected cells.
D000328:Adult; D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002460:Cell Line; D005347:Fibroblasts; D005976:Glutaral / Q000494:pharmacology*; D000882:Haplorhini; D006564:Herpesviridae; D006801:Humans; D007231:Infant, Newborn; D007372:Interferons / Q000096:biosynthesis*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D013045:Species Specificity
D000447:Aldehydes; D007372:Interferons; D005976:Glutaral
Production d'interféron humain de type I par des lymphocytes au contact de cellules infectées par le virus herpès et fixées par le glutaraldéhyde.