Brain and CSF proteins in Creutzfeldt-Jakob disease.
Cerebrospinal fluid was analyzed from 8 patients with Creutzfeldt-Jakob disease. No special abnormalities were found concerning cells, total protein content or the concentrations of albumin and IgG. Routine agar gel electrophoresis was normal.  Grey and white cerebral matter were analyzed from 1 patient. The total protein content was reduced in grey matter and on isoelectric focusing a distinct band at pH 8.8 was absent.
D000368:Aged; D000418:Albumins / Q000032:analysis; D001609:Beta-Globulins / Q000032:analysis; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D007562:Creutzfeldt-Jakob Syndrome / Q000378:metabolism*; D005260:Female; D005625:Frontal Lobe / Q000032:analysis*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000032:analysis*
D000418:Albumins; D001609:Beta-Globulins; D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G; D009419:Nerve Tissue Proteins