Immunisation against heterologous type II collagen induces arthritis in mice.
The induction of polyarthritis in rats by intradermal immunisation with homologous or heterologous type II collagen incomplete or incomplete Freund's adjuvant was reported recently by Trentham et al. We have now produced a similar disease in certain strains of mice.
D000276:Adjuvants, Immunologic; D000818:Animals; D001168:Arthritis / Q000276:immunology*; D001169:Arthritis, Experimental / Q000276:immunology*; D002417:Cattle; D003094:Collagen / Q000276:immunology*; D000939:Epitopes; D007114:Immunization; D046911:Macromolecular Substances; D051379:Mice; D011487:Protein Conformation; D013045:Species Specificity; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000939:Epitopes; D046911:Macromolecular Substances; D003094:Collagen