A cyst-forming Eimeriina found in the kangaroo imported from Australia.
One pair of grey kangaroos was imported from Australia in July 1974. One month after arrival they successively died of serious intestinal bleeding. On biopsy, the epithelium was destroyed and replaced with necrotic degeneration with numerous dot-like flecks of bleeding from the stomach till the jejunum. On histopathological examinations, the epithelium was composed of swollen glandular cells which form giant cells with eccentrically displaced nuclei. The cell forms a cyst which develops solitarily and gathers together to form a racemous shape. These cysts are bound to the thick wall and the parasites are found in the vesicular space. Several sequences of the parasite growth are demonstrated. The parasites migrated initially into the cytoplasm and then to the nucleus of the glandular cell in which they grow, then the cyst is formed and finally the parasites flow out to penetrate again into normal cells. The parasite cell changes to crescent- or spindle-shape as a tachyzoite. The relative nucleic acid content of the parasite in the host cell or its nucleus is measured by spectrophotometry and fluorometry. The data suggest that the parasites are reproduced in intestinal glandular cells of the kangaroo.
D000818:Animals; D016782:Apicomplexa / Q000032:analysis / Q000254:growth & development / Q000302:isolation & purification*; D001315:Australia; D004247:DNA / Q000032:analysis; D005260:Female; D007413:Intestinal Mucosa / Q000469:parasitology; D007614:Macropodidae / Q000469:parasitology*; D008297:Male; D008394:Marsupialia / Q000469:parasitology*; D011528:Protozoan Infections / Q000469:parasitology; D011529:Protozoan Infections, Animal; D012313:RNA / Q000032:analysis
D012313:RNA; D004247:DNA