Abnormal lipid composition of fat tissue in human mesenteric panniculitis.
Mesenteric fat tissue obtained at autopsy from 6 patients with mesenteric panniculitis (MP) were found to contain significant amounts of cholesteryl esters (CE). In addition, samples from 3 of these cases were found to contain 0.5-1.3% free cholesterol, 0.9-1.9% free fatty acids (FFA), 0.6-2.5% l-alkyl glyceryl ether diesters and small amounts of squalene. Two of these tissues also contained alk-l-enyl glyceryl ether diesters. The fatty acid compositions of the CE, FFA, triacylglycerides and glyceryl ether diesters (GEDE) were determined and oleic acid (18:1) was found to be the major fatty acid. The alkyl group composition of the GEDE consisted essentially of 16:0 and 18:0 and 18:1 carbon atoms in both types of ethers.
D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D000368:Aged; D002788:Cholesterol Esters / Q000378:metabolism; D004987:Ethers / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D005990:Glycerol / Q000031:analogs & derivatives / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008643:Mesentery; D008875:Middle Aged; D010742:Phospholipid Ethers; D012187:Retroperitoneal Space; D012867:Skin; D013185:Squalene / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism; D008061:Whipple Disease / Q000378:metabolism*
D002788:Cholesterol Esters; D004987:Ethers; D005227:Fatty Acids; D010742:Phospholipid Ethers; D014280:Triglycerides; D013185:Squalene; D005990:Glycerol