Intravascular persistence of hydroxyethyl starch (HES) after serial granulocyte collections using HES in man.
In 30 granulocyte donors undergoing one or more infusions of 6% hydroxyethyl starch (HES) solution plasma HES concentrations were measured by single radial immunodiffusion. Serial HES applications led to a cumulative increase in plasma HES levels. Up to 3 months after the last HES infusion, plasma concentrations in the range of 3 mg/ml were demonstrable. A possible influence of HES deposits upon reticuloendothelial system function is discussed.
D000328:Adult; D001782:Blood Donors; D005260:Female; D006098:Granulocytes / Q000637:transplantation; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000032:analysis / Q000097:blood*; D005779:Immunodiffusion; D008297:Male; D008875:Middle Aged; D013213:Starch / Q000031:analogs & derivatives*; D013997:Time Factors
D006895:Hydroxyethyl Starch Derivatives; D013213:Starch