Cleavage of mouse ribosomal RNAs by the endonuclease associated with Newcastle disease virus.
Mouse ribosomal ribonucleic acids (rRNAs) are specifically cleaved to polynucleotides of lower molecular mass by the endonuclease associated with Newcastle disease virus (NDV). The 28 S RNA yielded a fragment of about Mr = 1.7 X 10(5) which is resistant to the endonuclease. We assume that one molecule of 28 S RNA contains one such resistant region. 18 S RNA does not possess resistant regions of this character and it is cleaved by the endonuclease to smaller molecules.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor; D004722:Endoribonucleases / Q000378:metabolism*; D051379:Mice; D008970:Molecular Weight; D009522:Newcastle disease virus / Q000201:enzymology*; D012335:RNA, Ribosomal / Q000378:metabolism*
D012335:RNA, Ribosomal; D004722:Endoribonucleases