Malignant melanoma and histiocytofibroma.
In patients with malignant melanoma, histiocytofibromas often appeared to be present. The frequency of this association has been determined in 60 female and 40 male patients, and compared with age- and sex-matched controls. Histiocytofibromas are significantly more common in females with malignant melanoma than in controls. This relationship is not found in males. Therefore, it would seem important to make a careful examination of nevocytic nevi in women having this benign tumour because of the high risk of developing a malignant melanoma.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D012878:Skin Neoplasms / Q000453:epidemiology*