[Diagnosis of increased thrombotic tendency with chromogenic substrates].
In 185 patients suffering from increased thrombotic tendency and in 40 healthy individuals, the following parameters were assayed by the aid of chromogenic substrates: antithrombin III, plasminogen, immediate and total antiplasmin. Furthermore, the vascular activator of plasminogen and the spontaneous aggregation of platelets were examined by other methods. Alterations of plasmatic parameters which are likely to cause an increased thrombotic tendency were detected in 10% of all cases. In patients suffering from arterial thrombotic manifestations hyperactive platelets were found in 42%.
D000990:Antithrombin III / Q000032:analysis; D002863:Chromogenic Compounds; D006801:Humans; D009842:Oligopeptides; D010958:Plasminogen / Q000032:analysis; D010974:Platelet Aggregation; D013927:Thrombosis / Q000097:blood / Q000175:diagnosis*; D000979:alpha-2-Antiplasmin / Q000032:analysis
D002863:Chromogenic Compounds; D009842:Oligopeptides; D000979:alpha-2-Antiplasmin; C018788:valyl-leucyl-lysine 4-nitroanilide; D000990:Antithrombin III; D010958:Plasminogen
Diagnostik der erhöhten Thrombosebereitschaft mit chromogenene Substraten.