title: [Urinary alanine aminopeptidase excretion in children: reference values and effect of nephrotropic contrast media].
abstract: The catalytic activity of alanine aminopeptidase (EC 3.4.11.2) in urine shows a clear cut difference between boys (1530 mU/d X m2) and girls (1143 mU/d X m2). Nineteen children (preterms to 14 years) received contrast media (loxaglate (Hexabrix) (N = 15) or lotalamate (Conray 70) (N = 4] according to the diagnostic indication. The alanine aminopeptidase activity increases to 10-fold of the initial value in the loxaglate and 19-fold of the initial value in the lotalamate group. These results demonstrate a much higher response of the kidney to contrast medium in children than in adults.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000626:Aminopeptidases / Q000652:urine*; D018826:CD13 Antigens; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000000981:diagnostic imaging*; D008297:Male; D011859:Radiography; D012016:Reference Values; D012737:Sex Factors
chemical_list: D003287:Contrast Media; D000626:Aminopeptidases; D018826:CD13 Antigens
vernacular_title: Alaninaminopeptidase-Ausscheidung bei Kindern: Referenzbereiche und der Einfluss nierengängiger Kontrastmittel.