[Adenosine deaminase activity in leukemia patients].
The activities of adenosine deaminase (ADA) were measured in the blood plasma, erythrocytes, and lymphocytes of healthy reference persons and in patients affected with leukaemia. ADA is increased in patients with acute immature cell leukaemia, in patients with chronic lymphatic leukaemia it is comparatively low in lymphocytes. In chronic myeloic leukaemia ADA activities are different depending on the activity of the disease. ADA-activities in the blood plasma, erythrocytes, and lymphocytes do not correlate with each other. ADA-activities in leukaemias may be regarded as an indicator of increased purin metabolism rather a as parameter of disturbed cellular immunofunction.
D000208:Acute Disease; D000243:Adenosine Deaminase / Q000097:blood*; D000328:Adult; D000368:Aged; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D007938:Leukemia / Q000201:enzymology*; D007945:Leukemia, Lymphoid / Q000201:enzymology; D007951:Leukemia, Myeloid / Q000201:enzymology; D008214:Lymphocytes / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D009700:Nucleoside Deaminases / Q000097:blood*; D011687:Purines / Q000378:metabolism
D011687:Purines; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase
Adenosindesaminasseaktivitäten bei Leukämiepatienten.