title: Distinctive sequence of human mitochondrial ribosomal RNA genes.
abstract: The nucleotide sequence spanning the ribosomal RNA (rRNA) genes of cloned human mitochondrial DNA reveals an extremely compact genome organization wherein the putative tRNA genes are probably 'butt-jointed' around the two rRNA genes. The sequences of the rRNA genes are significantly homologous in some regions to eukaryotic and prokaryotic sequences, but distinctive; the tRNA genes also have unusual nucleotide sequences. It seems that human mitochondria did not originate from recognizable relatives of present day organisms.
mesh_terms: D001483:Base Sequence; D005075:Biological Evolution; D002874:Chromosome Mapping; D004272:DNA, Mitochondrial / Q000235:genetics*; D005796:Genes; D006801:Humans; D008970:Molecular Weight; D012329:RNA, Bacterial / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics*; D012343:RNA, Transfer / Q000235:genetics*
chemical_list: D004272:DNA, Mitochondrial; D012329:RNA, Bacterial; D012335:RNA, Ribosomal; D012343:RNA, Transfer