Entamoeba histolytica "toxin": fetuin neutralizable and lectin-like.
Extracts of Entamoeba histolytica produce rounding and agglutination of mammalian cells in tissue culture. This effect is inhibited or reversed by serum, by the serum glycoprotein, fetuin, or by N-acetyl-D-galactosamine. Concanavalin A produces a similar cytotoxic effect that is blocked or reversed by alpha-methyl mannoside. These properties suggest that the amebal "toxin" has a lectin-like activity.
D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D003470:Culture Media; D003603:Cytotoxins / Q000032:analysis* / Q000037:antagonists & inhibitors; D004748:Entamoeba histolytica / Q000032:analysis*; D037102:Lectins / Q000032:analysis*; D000509:alpha-Fetoproteins / Q000494:pharmacology*
D003470:Culture Media; D003603:Cytotoxins; D037102:Lectins; D000509:alpha-Fetoproteins