title: A biochemical study of adult and cystic stages of Echinococcus granulosus of human and animal origin from Kenya.
abstract: A comparative biochemical study was performed on adult and cystic stages of Echinococcus granulosus. Basic quantitative differences in metabolism were apparent between the cystic forms of sheep origin from the UK and Kenya which suggest that each may represent a different geographical strain or sub-strain. The biochemistry of the human and sheep forms from Kenya was very similar, which probably reflects a certain close affinity between the two. The fact that the cattle, goat and camel forms of E. granulosus, from that country, were distinct biochemically, both from each other and from the sheep and human types, suggests the existence of an unusually complex strain picture there, and that these organisms are either non-infective or only poorly infective to man. The differences in biochemical composition and metabolism observed between adults produced experimentally and those obtained from naturally infected dogs, may have been as a result of their original hydatid source and/or their differing stage of development.
mesh_terms: D000818:Animals; D002417:Cattle / Q000469:parasitology; D004247:DNA / Q000032:analysis; D004446:Echinococcus / Q000032:analysis / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D006041:Goats / Q000469:parasitology; D006801:Humans; D007630:Kenya; D008055:Lipids / Q000032:analysis; D011506:Proteins / Q000032:analysis; D012313:RNA / Q000032:analysis; D012756:Sheep / Q000469:parasitology
chemical_list: D008055:Lipids; D011506:Proteins; D012313:RNA; D006003:Glycogen; D004247:DNA; D005947:Glucose