Localized comedo formation after cobalt irradiation.
Following Cobalt-60 irradiation for a left frontotemporal tumor, a 61-year-old woman developed comedones on the forehead. These changes responded to conventional acne therapy with retinoic acid. Multiple acneigenic factors were implicated in the pathogenesis of her lesions.
D001932:Brain Neoplasms / Q000532:radiotherapy; D003037:Cobalt Radioisotopes / Q000009:adverse effects*; D005260:Female; D006201:Hair Diseases / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010166:Palliative Care; D011867:Radioisotope Teletherapy / Q000009:adverse effects; D012627:Sebaceous Glands; D014212:Tretinoin / Q000627:therapeutic use
D003037:Cobalt Radioisotopes; D014212:Tretinoin