Increased biological activity of dimers of oxymorphone and enkephalin: possible role of receptor crosslinking.
D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D001921:Brain / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D004723:Endorphins / Q000494:pharmacology*; D004745:Enkephalins / Q000378:metabolism / Q000494:pharmacology*; D006168:Guinea Pigs; D004091:Hydromorphone / Q000031:analogs & derivatives*; D007082:Ileum / Q000187:drug effects; D007700:Kinetics; D009119:Muscle Contraction / Q000187:drug effects; D010111:Oxymorphone / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000378:metabolism; D013329:Structure-Activity Relationship
D004723:Endorphins; D004745:Enkephalins; D011957:Receptors, Opioid; D010111:Oxymorphone; D004091:Hydromorphone