Mechanism of interferon action: cloned human leukocyte interferons induce protein kinase and inhibit vesicular stomatitis virus but not reovirus replication in human amnion cells.
D002478:Cells, Cultured; D003001:Cloning, Molecular; D004790:Enzyme Induction / Q000187:drug effects; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007962:Leukocytes / Q000378:metabolism; D010448:Peptide Initiation Factors / Q000378:metabolism; D011494:Protein Kinases / Q000096:biosynthesis*; D012087:Reoviridae / Q000254:growth & development; D014721:Vesicular stomatitis Indiana virus / Q000254:growth & development; D014779:Virus Replication / Q000187:drug effects*
D010448:Peptide Initiation Factors; D007372:Interferons; D011494:Protein Kinases