title: Production of interferon in human diploid cells at different population doubling levels.
abstract: Interferon (IFN) yield after superinduction declined gradually by in vitro senescence of the cells, while it remained unchanged in IFN-pretreated cells. IFN yield after stimulation with Newcastle disease virus remained unchanged by in vitro senescence.
mesh_terms: D002460:Cell Line; D002470:Cell Survival; D005347:Fibroblasts / Q000166:cytology* / Q000378:metabolism*; D006801:Humans; D007372:Interferons / Q000096:biosynthesis* / Q000494:pharmacology; D009522:Newcastle disease virus; D011070:Poly I-C / Q000494:pharmacology
chemical_list: D007372:Interferons; D011070:Poly I-C