title: [Isoprinosine and human chromosomes (author's transl)].
abstract: The incidence of chromatid and chromosome abnormalities and that of SCE induced by isoprinosine was studied in human lymphocyte cultures. No effect was detected in vivo. In vitro the only effect detected was an increased SCE incidence when isoprinosine at 1000 microgram/ml in culture medium was used.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002842:Chromatids / Q000187:drug effects; D002869:Chromosome Aberrations; D003434:Crossing Over, Genetic / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012854:Sister Chromatid Exchange / Q000187:drug effects*
chemical_list: D007288:Inosine; D007542:Inosine Pranobex
vernacular_title: Isoprinosine et chromosomes humains.