Bladder neck dysfunction: the effect of the alpha-adrenergic blocking agent phentolamine on bladder neck dysfunction and a fluorescent histochemical study of bladder neck smooth muscle.
Urodynamic examinations and fluorescent histochemical studies suggest that patients with bladder neck obstruction can be divided into two main groups (responders and nonresponders) based on the response of their urinary flow rate to phentolamine and that the adrenergic nervous system of the bladder neck has an important effect on the response in responders.
D000320:Adrenergic Fibers / Q000033:anatomy & histology*; D000317:Adrenergic alpha-Antagonists; D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D009130:Muscle, Smooth / Q000033:anatomy & histology; D010646:Phentolamine; D011312:Pressure; D011470:Prostatic Hyperplasia / Q000503:physiopathology; D011472:Prostatitis / Q000503:physiopathology; D014521:Urethra / Q000503:physiopathology; D001743:Urinary Bladder / Q000294:innervation*; D001748:Urinary Bladder Neck Obstruction / Q000503:physiopathology*; D014563:Urodynamics / Q000187:drug effects
D000317:Adrenergic alpha-Antagonists; D010646:Phentolamine