title: Acute oral toxicity of hexachlorocyclohexane and X-factor to poultry Gallus domesticus.
abstract: Twelve week old male birds (Gallus domesticus) were intragastrically administered technical grade samples of Benzene hexachloride (gamma-isomer: 13%) and X-factor (gamma-isomer: 16%) [a by-product obtained during separation of gamma-isomer from (BHC)] in capsules with a view of establishing oral LD50 values. The computed oral LD50 values for BHC and X-factor were 596.8 and 589.5 mg/kg body weight, respectively, indicating no variation in their susceptibility to these pesticides. observations on symptoms, feed intake, body weight gain, organ weights, and microscopic examination of vital organs are reported.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D001556:Hexachlorocyclohexane / Q000633:toxicity*; D007536:Isomerism; D007928:Lethal Dose 50; D008099:Liver / Q000473:pathology; D008297:Male; D009929:Organ Size / Q000187:drug effects; D011201:Poultry Diseases / Q000139:chemically induced* / Q000401:mortality / Q000473:pathology
chemical_list: D001556:Hexachlorocyclohexane