Diabetic macular edema in juvenile- and adult-onset diabetes.
A retrospective study of 103 patients referred because of diabetic retinopathy graded the degree of maculopathy on the basis of fluorescein angiography. Patients with juvenile-onset diabetes (that is, onset before the age of 40 years), had a higher rate of neovascularization of the disk or retina at early stages of maculopathy than patients with adult-onset diabetes. Greater capillary closure at each degree of maculopathy in the group with juvenile-onset diabetes may explain this difference.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology*; D003930:Diabetic Retinopathy / Q000175:diagnosis / Q000473:pathology*; D004487:Edema / Q000473:pathology; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008875:Middle Aged; D009389:Neovascularization, Pathologic