Interaction of polynucleotides with natural and model membranes.
Polynucleotides adsorb on natural and model phospholipid membranes in the presence of Mg2+-cations. Adsorption of nucleic acids on membranes results in a considerable change of their secondary structure. The presence of model phosphatidylcholine membranes greatly stimulates the rate of the synthesis of RNA by E. coli RNA-polymerase on DNA template.
D000818:Animals; D004247:DNA / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology; D006358:Hot Temperature; D007425:Intracellular Membranes / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism*; D008745:Methylation; D008930:Mitochondria, Liver / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D011119:Polynucleotides / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis / Q000378:metabolism; D051381:Rats
D008081:Liposomes; D010713:Phosphatidylcholines; D010743:Phospholipids; D011119:Polynucleotides; D012313:RNA; D004247:DNA; D012321:DNA-Directed RNA Polymerases