[Detoxifying effect of RNA].
The documented facts are presented concerning the detoxifying effect of NaRNA when injected together with adsorbed DPT vaccine, TAB-tetanus vaccine and typhoid vaccine with sextitoxoid. The intraperitoneal and oral administration of the preparation of RNA was shown to protect rodents from the toxic effect of the vaccines. In these experiments the tests were made to determine the following characteristics: LD50 of the vaccine, survival time, the change of body weight, the spleen index, efficiency, food and water consumption. A decrease in the toxicity of the prophylactic preparations was not accompanied by a decrease in vaccinal immunity.
D000284:Administration, Oral; D000818:Animals; D001428:Bacterial Vaccines / Q000633:toxicity*; D001835:Body Weight; D004168:Diphtheria Toxoid / Q000633:toxicity; D007274:Injections, Intraperitoneal; D007928:Lethal Dose 50; D051379:Mice; D010567:Pertussis Vaccine / Q000633:toxicity; D012313:RNA / Q000008:administration & dosage / Q000627:therapeutic use*; D013745:Tetanus Toxoid / Q000633:toxicity; D014436:Typhoid-Paratyphoid Vaccines / Q000633:toxicity
D001428:Bacterial Vaccines; D004168:Diphtheria Toxoid; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid; D014436:Typhoid-Paratyphoid Vaccines; D012313:RNA
Detoksitsiruiushchiĭ éffekt RNK.