Perineural glands in normal and hyperplastic prostates.
Serial sections from 1 block of either a normal or hyperplastic prostate demonstrated at least 2 foci of perineural invasion in 7 of 8 consecutive autopsies. In addition to the perineural invasion a close relationship was found among nerves, glandular epithelium and vascular structures in all 8 autopsies. Although there are differences between the epithelium in perineural invasion in carcinoma and in normal or hyperplastic prostates perineural invasion can no longer be regarded as unequivocal evidence of malignancy.
D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000473:pathology*