Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2.
Acyclovir and human interferon displayed an additive to synergistic effect in reducing the number of herpes simplex viral plaque-forming units in Vero cells, suggesting a therapeutic potential for such combination therapy.
D000212:Acyclovir; D000998:Antiviral Agents / Q000494:pharmacology*; D004357:Drug Synergism; D006147:Guanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007372:Interferons / Q000494:pharmacology*; D018139:Simplexvirus / Q000187:drug effects*; D010948:Viral Plaque Assay
D000998:Antiviral Agents; D006147:Guanine; D007372:Interferons; D000212:Acyclovir