title: A contribution to the postnatal enzymatic state of maturity of gyrus hippocampi in the embryofetal alcohol syndrome of the rat.
abstract: The influence of maternal chronic alcoholism on fetal brain development was investigated in rats. A decrease in the activity of succinate, glycerin-1-phosphate, glucose-6-phosphate dehydrogenases and of tetrazolium reductases was found. The amount of total RNA was reduced in the neonates with alcohol damage. Moreover, a retardation of myelinisation at the time of birth was observed.
mesh_terms: D000818:Animals; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D006624:Hippocampus / Q000201:enzymology*; D009246:NADH Tetrazolium Reductase / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism*; D011247:Pregnancy; D012313:RNA / Q000378:metabolism; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D012313:RNA; D010088:Oxidoreductases; D005993:Glycerolphosphate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D009246:NADH Tetrazolium Reductase