HLA antigens in cases of giant cell arteritis.
HLA tissue-type antigen determination for A-, B- and C-antigens in 88 patients suffering from giant cell arteritis of the temporal artery showed no significant deviations as compared to a control material of 3164 blood donors. A weak indication of association with antigen HLA-B8 appeared to be of interest due to a corresponding indication in previous investigation. The patients were a mixed hospital material, consisting of cases of clinical temporal arteritis and patients with polymyalgia rheumatica. There was an overrepresentation of women (77%). Familial occurrence was demonstrated sporadically (3 pairs of siblings).
D000368:Aged; D000939:Epitopes; D005260:Female; D013700:Giant Cell Arteritis / Q000235:genetics / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011111:Polymyalgia Rheumatica / Q000276:immunology
D000939:Epitopes; D006680:HLA Antigens