gamma-Glutamyl transpeptidase of human amniotic fluid.
gamma-Glutamyl transpeptidase (GGTP) activity in normal amniotic fluids and corresponding maternal sera obtained at various gestational periods was measured. The ontogenic pattern of enzyme activity in amniotic fluid is very similar to alpha fetoprotein (AFP). However, the levels of these two proteins behaved differently in corresponding maternal sera. Also, in amniotic fluids obtained from pregnancies with neural tube defects (NTD), only AFP concentration was abnormally high whereas GGTP activity was normal.
D000653:Amniotic Fluid / Q000032:analysis / Q000201:enzymology*; D005260:Female; D005978:Glutathione / Q000032:analysis; D006801:Humans; D009436:Neural Tube Defects / Q000201:enzymology*; D010088:Oxidoreductases / Q000032:analysis; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000032:analysis*; D005723:gamma-Glutamyltransferase / Q000032:analysis*
D000509:alpha-Fetoproteins; D010088:Oxidoreductases; C020667:glutathione oxidase; D005723:gamma-Glutamyltransferase; D005978:Glutathione