Concentration of immunoreactive trypsin and activity of pancreatic isoamylase in serum compared in pancreatic diseases.
We measured the concentration of immunoreactive trypsin and the enzymic activity of pancreatic isoamylase in sera from 103 patients with pancreatic diseases and 29 other subjects serving as a reference group. Almost all patients with pancreatic diseases had abnormal values for both enzymes. A strong positive correlation between these two variables over a 1000-fold range was observed.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D006026:Glycoside Hydrolases / Q000097:blood*; D006801:Humans; D007517:Isoamylase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000201:enzymology*; D010195:Pancreatitis / Q000201:enzymology*; D011863:Radioimmunoassay; D014357:Trypsin / Q000097:blood* / Q000276:immunology; D000516:alpha-Amylases / Q000097:blood*
D000681:Amylases; D006026:Glycoside Hydrolases; D000516:alpha-Amylases; D007517:Isoamylase; D014357:Trypsin