title: [Learning in rats with differing emotional responsiveness and its relation to brain monoamines].
abstract: The ability for learning was studied in two groups of Wistar line rats divided by susceptibility to the audiogenic stress-stimulation as compared with the monoamines level in various brain structures. The best ability to learn avoidance reaction in a shuttlebox was shown by animals non-resistant to the stress stimulus as compared with the resistant rats, which correlated positively with the exploratory activity in "the open field". The distinct feature of the animals non-resistant to the stress stimulation consisted in a higher reactivity of the monoamine systems, mainly of the noradrenergic system. This group of animals was also characterized by a higher dopamine content and a lower noradrenaline content in the brain-stem. Decreased activity of the brain dopamine-beta-hydroxylase in animals non-resistant to the stress stimulus, has been suggested.
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001679:Biogenic Amines / Q000032:analysis*; D001923:Brain Chemistry; D004298:Dopamine / Q000032:analysis; D004644:Emotions / Q000502:physiology*; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000032:analysis
chemical_list: D001679:Biogenic Amines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D004298:Dopamine; D009638:Norepinephrine
vernacular_title: Obuchenie krys s razlichnoĭ émotsional'noĭ reaktivnost'iu i ee s monoaminami mozga.