Vitamin A transport complex during treatment with an oral aromatic retinoid (RO 10-9359).
No significant changes were noted in the serum levels or molar ratios of vitamin A, retinol-binding protein (RBP) and prealbumin even during long-term (up to 15 months) treatment with RO 10-9359 in 19 patients with normal renal function. Nor did any significant alteration occur in the highly significant correlations between vitamin A and RBP, and between RBP and prealbumin. In 3 patients with slightly elevated serum creatinine, some tendency towards an elevation of vitamin A and RBP levels was seen.
D000328:Adult; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011228:Prealbumin / Q000032:analysis; D011565:Psoriasis / Q000188:drug therapy; D012177:Retinol-Binding Proteins / Q000032:analysis*; D014212:Tretinoin / Q000031:analogs & derivatives*; D014801:Vitamin A / Q000097:blood*
D011228:Prealbumin; D012177:Retinol-Binding Proteins; D014801:Vitamin A; D014212:Tretinoin; D005050:Etretinate