The validation of animal tests of anxiety--pharmacological implications.
The behavioral, physiological and pharmacological validation of the social interaction test of anxiety is described. The effects of benzodiazepine and non-benzodiazepine anxiolytics, other classes of drugs and of anxiogenic drugs are discussed.
D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001007:Anxiety / Q000097:blood / Q000139:chemically induced; D001569:Benzodiazepines; D003345:Corticosterone / Q000097:blood; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D006801:Humans; D051381:Rats; D012919:Social Behavior
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D000324:Adrenocorticotropic Hormone; D003345:Corticosterone