Activation of human and mouse 2-5A synthetases and mouse protein P1 kinase by nucleic acids. Structure-activity relationships and correlations with inhibition of protein synthesis and interferon induction.
D015088:2',5'-Oligoadenylate Synthetase; D000818:Animals; D004789:Enzyme Activation; D006801:Humans; D007372:Interferons / Q000096:biosynthesis*; D051379:Mice; D009696:Nucleic Acids / Q000494:pharmacology*; D009713:Nucleotidyltransferases / Q000378:metabolism*; D011119:Polynucleotides / Q000494:pharmacology; D014176:Protein Biosynthesis / Q000187:drug effects*; D011494:Protein Kinases / Q000378:metabolism*; D012330:RNA, Double-Stranded / Q000494:pharmacology; D013329:Structure-Activity Relationship
D009696:Nucleic Acids; D011119:Polynucleotides; D012330:RNA, Double-Stranded; D007372:Interferons; D011494:Protein Kinases; D009713:Nucleotidyltransferases; D015088:2',5'-Oligoadenylate Synthetase