Non-coordinate regulation of RNA synthesis in Escherichia coli exposed to 0 degrees C.
A non-coordinate mode of regulation of RNA synthesis is observed in Escherichia coli cells during exposure to 0 degrees C. The stable RNA synthesis is preferentially inhibited with simultaneous accumulation of messenger RNA. The species of RNA synthesized at 0 degrees C was determined by several criteria such as sedimentation value in sucrose gradients, DNA-RNA hybridization, half life measurements, protein synthesizing capacity and its functional rate of decay. The mode of regulation of RNA synthesis at 0 degrees C is unique and is distinct from the non-coordinate regulation observed during amino acid starvation under stringent control.
D001426:Bacterial Proteins / Q000096:biosynthesis; D003080:Cold Temperature; D004926:Escherichia coli / Q000378:metabolism*; D007700:Kinetics; D009693:Nucleic Acid Hybridization; D014176:Protein Biosynthesis; D012329:RNA, Bacterial / Q000096:biosynthesis*; D014158:Transcription, Genetic
D001426:Bacterial Proteins; D012329:RNA, Bacterial