A rapid, sensitive myeloperoxidase stain using 4-chloro-1-naphthol.
The substitution of 4-chloro-1-naphthol for benzidine-containing compounds used in the myeloperoxidase stain for distinguishing granulocytes from lymphoid blood elements is described. 4-Chloro-1-naphthol is an acceptable substitute for benzidine compounds, which are considered to be carcinogenic. The feasibility of using this method on peripheral blood and bone-marrow films is discussed.
D006098:Granulocytes / Q000201:enzymology; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology; D009284:Naphthols; D009195:Peroxidase / Q000032:analysis*; D010544:Peroxidases / Q000032:analysis*; D013194:Staining and Labeling
D009284:Naphthols; C025917:4-chloro-1-naphthol; D010544:Peroxidases; D009195:Peroxidase