Antigenicities of mucins - their relevance to tumour associated and stage specific embryonic antigens.
It can now be envisaged that there exists a distinct set of differentiation antigens formed by linear (i type) or branched (I-type) oligosaccharides and their fucosylated (and perhaps sialylated) derivatives. Several of these antigens are expressed in secreted glycoproteins (mucins) which are relatively abundantly available. Thus mucins can serve as valuable sources of oligosaccharide haptens of differentiation antigens just as they have done in the past with the major blood group antigens.
D000818:Animals; D000941:Antigens / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology; D001789:Blood Group Antigens / Q000276:immunology; D004622:Embryo, Mammalian / Q000276:immunology; D005752:Gastric Mucins / Q000276:immunology; D006801:Humans; D009077:Mucins / Q000276:immunology*
D000941:Antigens; D000951:Antigens, Neoplasm; D001789:Blood Group Antigens; D005752:Gastric Mucins; D009077:Mucins