[Turnover of chromatin proteins in rat liver during induction of RNA synthesis by electrostimulation of the hypothalamus].
It has been shown that the induction of D-RNA synthesis in rat liver nuclei by electrostimulation of hypothalamus is accompanied by a decrease in chromatin protein synthesis and an increase in phosphorylation and acetylation of chromatin proteins. The decrease of the histone synthesis is mainly due to the decrease of [14C]lysine and [14C]alanine incorporation into histones H1 and H4. The relationship between H1, H2b-H3, H2a and H4 histone fractions remains unchanged. Electrostimulation of hypothalamus increases acetylation of H2a and H4 histone fractions and phosphorylation of all histones with the exception of histone H1.
D000107:Acetylation; D000818:Animals; D002843:Chromatin / Q000378:metabolism*; D004558:Electric Stimulation; D006657:Histones / Q000096:biosynthesis; D007031:Hypothalamus / Q000502:physiology*; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D009698:Nucleoproteins / Q000096:biosynthesis*; D010766:Phosphorylation; D012313:RNA / Q000096:biosynthesis*; D051381:Rats
D002843:Chromatin; D006657:Histones; D009698:Nucleoproteins; D012313:RNA
Obmen belkov khromatina pecheni krys pri induktsii senteza RNK elektrostimuliatsieĭ gipotalamusa.