[Tumoral development of prolactin-secreting pituitary adenomas during pregnancy. Therapeutic approaches (author's transl)].
During pregnancy the volume of prolactin-secreting pituitary adenomas tends to increase dangerously for surrounding structures, especially the optic chiasma. When rapid growth occurs, at least three therapeutic approaches are possible: resection of the adenoma, temporization under monitoring and administration of bromocriptine. The latter treatment, which seems to be of particular value, was applied to a female patient and was followed by prompt regression of optic chiasma compression. However, as bromocriptine was given concurrently with chlormadinone acetate, this excellent result cannot be ascribed to bromocriptine alone.
D000236:Adenoma / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D002715:Chlormadinone Acetate / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011388:Prolactin / Q000378:metabolism*
D002715:Chlormadinone Acetate; D001971:Bromocriptine; D011388:Prolactin
Evolution tumorale des adénomes à prolactine au cours de la grossesse. Modalités thérapeutiques (2 observations).