Substance P in ovarian carcinoid.
A high content of substance P (124 ng/g wet tissue) was demonstrated by radioimmunoassay in lymph node metastases in a patient with bilateral ovarian carcinoid tumours. The plasma substance P level was elevated but urinary 5-hydroxyindoleacetic acid (5-HIAA) was low. It is suggested that, in some carcinoid patients, an elevated plasma substance P level may help diagnosis and follow-up when urinary 5-HIAA is normal.
D000328:Adult; D002276:Carcinoid Tumor / Q000378:metabolism* / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008198:Lymph Nodes / Q000378:metabolism / Q000473:pathology; D008207:Lymphatic Metastasis; D010051:Ovarian Neoplasms / Q000378:metabolism* / Q000473:pathology; D013373:Substance P / Q000097:blood / Q000378:metabolism*
D013373:Substance P; D006897:Hydroxyindoleacetic Acid