title: Analysis and the effects of some drugs on the metabolism of phenylethylamine and phenylacetic acid.
abstract: Phenylethylamine has been reliably measured using radioenzymatic, gas chromatographic, mass spectromatic and gas chromatographic - mass spectrometric methods. Phenylacetic acid has been measured using gas chromatographic and gas chromatographic-mass spectrometric methods. Phenylethylamine concentrations are increased primarily by phenylalanine, its amino acid precursor and by such monoamine oxidase inhibitors as L-deprenyl and pargyline. Phenylethylamine administration influences other neurotransmitters such as dopamine, norepinephrine and 5-hydroxytryptamine. It also effects the tyramines and possibly tryptamine.
mesh_terms: D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002849:Chromatography, Gas; D006801:Humans; D008253:Macaca mulatta; D013058:Mass Spectrometry; D051379:Mice; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology*; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D010627:Phenethylamines / Q000032:analysis / Q000378:metabolism*; D010648:Phenylacetates / Q000032:analysis / Q000378:metabolism*; D010649:Phenylalanine / Q000494:pharmacology*; D051381:Rats
chemical_list: D008996:Monoamine Oxidase Inhibitors; D018377:Neurotransmitter Agents; D010627:Phenethylamines; D010648:Phenylacetates; C029261:phenethylamine; D010649:Phenylalanine; C025136:phenylacetic acid