Therapy of non-Hodgkin's lymphomas in relapse.
The authors present the results of treatment of 26 patients suffering from non-Hodgkin's lymphoma in relapse. Remission which preceded the relapse was obtained in all patients with combination chemotherapy CVP (cyclophosphamide, vincristine and prednisone). For a second-choice regimen the following treatment modalities were used: 1) DTIC + prednisone; 2) VM-26 + procarbazine + prednisone; or 3) therapeutic splenectomy + combination CVP. The best results (the longest second remission) were obtained in patients who underwent therapeutic splenectomy, followed by a CVP regimen.
D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy*; D009364:Neoplasm Recurrence, Local; D011241:Prednisone / Q000627:therapeutic use; D011344:Procarbazine / Q000627:therapeutic use; D013156:Splenectomy; D013713:Teniposide / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D007093:Imidazoles; D011344:Procarbazine; D014750:Vincristine; D003520:Cyclophosphamide; D013713:Teniposide; D011241:Prednisone