Retrograde labelling of retinogeniculate neurones in the cat by HRP uptake from the diffuse injection zone.
The effective uptake region for retrograde HRP labelling was investigated in the retinogeniculate system in the cat. Contrary to previous reports, labelling of ganglion cells was found not only in the retinal area projecting to the dense central zone of the injection site, but also in areas projecting to extensive regions of its surrounding diffuse zone in the lateral geniculate nucleus. It is concluded that the widely accepted view that retrograde HRP labelling occurs only by uptake of HRP from the dense zone of the injection site is erroneous.
D000818:Animals; D001370:Axonal Transport; D002415:Cats; D004525:Efferent Pathways / Q000033:anatomy & histology; D005154:Facial Nerve / Q000033:anatomy & histology*; D007839:Functional Laterality; D005830:Geniculate Ganglion / Q000033:anatomy & histology*; D006735:Horseradish Peroxidase; D009474:Neurons / Q000502:physiology*; D012160:Retina / Q000166:cytology / Q000502:physiology
D006735:Horseradish Peroxidase