[Bleomycin-induced tumor cell lysis caused by antibodies and complement].
The well-known cytotoxic mode of action of bleomycin up to now has been clarified exclusively by intracellular processes. Our findings however indicate that an immunologic effect induced by bleomycin can also lead to the destruction of tumor cells.
D000818:Animals; D000912:Antibodies, Neoplasm; D000920:Antibody-Dependent Cell Cytotoxicity; D001761:Bleomycin / Q000276:immunology* / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology*; D003165:Complement System Proteins; D006168:Guinea Pigs; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000276:immunology
D000912:Antibodies, Neoplasm; D001761:Bleomycin; D003165:Complement System Proteins
Bleomycin-induzierte Tumorzell-Lyse durch Antikörper und Komplement.