[Species specificity study of swine leukocyte interferon on different cell cultures].
The antiviral effect of swine leukocyte interferon was studied in cell cultures of different origins. Swine leukocyte interferon was demonstrated to protect human diploid fibroblasts. The cultures of primarily trypsinized mouse embryo fibroblasts and continuous bovine embryo tracheal cells are as sensitive to swine leukocyte interferon as human diploid cells. Studies of the age sensitivity of mouse fibroblast tissues to swine interferon showed the tissue sensitivity to interferon to decline markedly with age.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D051379:Mice; D013045:Species Specificity; D013552:Swine; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D007372:Interferons
Izuchenie vidovoĭ spetsifichnosti svinogo leĭkotsitarnogo interferona na razlichnykh kletochnykh kul'turakh.