Local immunity to Bacteroides gingivalis in periodontal disease.
The histopathologic status of gingival tissue was assessed according to the criteria of Page and Schroeder.(5) Rhodamine-labeled bacteria were used to assess the antigenic specificity of plasma cells in the tissue. Examination of tissue sections revealed that 31.6% of plasma cells in the advanced lesions bound the labeled bacterium, compared with only 3.1% of the cells in the early lesions. These results indicate that local immunity to Bacteroides gingivalis in greater in the more advanced than in the earlier forms of periodontal disease.
D000942:Antigens, Bacterial / Q000276:immunology; D001439:Bacteroides / Q000276:immunology*; D005881:Gingiva / Q000033:anatomy & histology / Q000276:immunology* / Q000382:microbiology; D005882:Gingival Diseases / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D012235:Rhodamines; D013194:Staining and Labeling / Q000379:methods
D000942:Antigens, Bacterial; D012235:Rhodamines; C027305:Lissamine Rhodamine B sulfonyl chloride