[Acetylcholinesterase containing neurons in the rat brain after DFP-pretreatment (author's transl)].
The AChE activity was demonstrated in some brain regions of adult rats after intoxication with DFP ( (di-isopropyl-fluorophosphate). Within these nuclear areas (Caudate-Putamen-Complex, Globus pallidus, Nucleus accumbens septi, Substantia nigra, Locus coeruleus) various proportions of the neuron population could be shown to be AChE positive. There is a characteristic morphology of the AChE containing neurons. Comparing them with staining and silver impregnation, cytological attributability appears feasible.
D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000166:cytology*; D002421:Caudate Nucleus / Q000166:cytology; D005917:Globus Pallidus / Q000166:cytology; D006651:Histocytochemistry; D007531:Isoflurophate / Q000506:poisoning*; D008125:Locus Coeruleus / Q000166:cytology; D008297:Male; D009474:Neurons / Q000201:enzymology*; D009714:Nucleus Accumbens / Q000166:cytology; D011699:Putamen / Q000166:cytology; D051381:Rats; D013194:Staining and Labeling; D013378:Substantia Nigra / Q000166:cytology
D007531:Isoflurophate; D000110:Acetylcholinesterase
Acetylcholinesterase-haltige Neurone im Gehirn der Ratte nach DFP-Intoxikation.