title: [Topicalities from gene technology. Protein synthesized by bacteria the better therapeutic alternative (author's transl)].
abstract: Compared with conventional methods for obtaining highly complicated natural substances such as peptide hormones and vaccine antibodies from animal or human tissues or cell culture, the synthesis of these therapeutically important substances in bacterial cells, made possible by gene technology, has the decisive advantage that the bacteria synthesize exclusively that protein whose appropriate genetic information has previously been obtained and insinuated into the bacterial cell under accurately controlled physicochemical conditions. Thus, the mmammalian protein produced in bacteria is purer and consequently freer from side-effects than material obtained from ammmalian cells.
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D004358:Drug Therapy; D005821:Genetic Techniques; D013006:Growth Hormone / Q000096:biosynthesis; D006514:Hepatitis B Surface Antigens / Q000096:biosynthesis; D006728:Hormones / Q000096:biosynthesis; D006801:Humans; D007372:Interferons / Q000096:biosynthesis; D010452:Peptide Biosynthesis; D014765:Viral Vaccines / Q000096:biosynthesis
chemical_list: D001426:Bacterial Proteins; D006514:Hepatitis B Surface Antigens; D006728:Hormones; D014765:Viral Vaccines; D013006:Growth Hormone; D007372:Interferons
vernacular_title: Aktuelles aus der Gentechnologie. Bakteriell synthetisierte Proteine als bessere therapeutische Alternative.