[Immunodiagnosis of cancer: requirements and results (author's transl)].
Theoretical aspects are considered on the requirements of immunological cancer tests. The criteria of clinical applicability are: Specificity, sensitivity, information with respect to tumour localisation. Immunodiagnostic tests cover the following areas: Early diagnosis on the basis of screening of the whole population or of risk groups, differential diagnosis, detection of relapse or metastases, prognosis. Experimental results are presented on a test for tumour detection. In a blind test study patients with clinically manifest tumours were recognized in about 80--90%, when using human fetal extract as antigen in the macrophage-electro-phoretic-mobility technique.
D000941:Antigens; D003937:Diagnosis, Differential; D005333:Fetus / Q000276:immunology; D006801:Humans; D008264:Macrophages / Q000276:immunology; D008403:Mass Screening; D004676:Myelin Basic Protein / Q000276:immunology; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009369:Neoplasms / Q000175:diagnosis*; D011379:Prognosis; D012698:Serologic Tests / Q000379:methods*; D014020:Tissue Extracts
D000941:Antigens; D004676:Myelin Basic Protein; D014020:Tissue Extracts
Immunodiagnostik des Krebses: Anforderungen und Ergebnisse.