Prostatic trauma and release of acid phosphatase. Radioimmunochemical and enzymatic comparison.
Radioimmunoassay for prostatic acid phosphatase and a conventional enzymatic method using alpha-naphthyl phosphate were employed to document the changes in serum levels of this enzyme following transurethral prostatectomy and prostatic massage. Thirty-four patients with histologically proved benign prostatic hyperplasia and 120 controls were studied. Consistent parallel elevations were noted after surgical trauma. A rapid clearance was observed with normal levels returning at twenty-four hours. Prostatic massage did not elicit a change by either method.
D000135:Acid Phosphatase / Q000097:blood / Q000378:metabolism*; D000368:Aged; D006801:Humans; D008297:Male; D008405:Massage; D008875:Middle Aged; D011467:Prostate / Q000201:enzymology / Q000293:injuries*; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000601:surgery; D011863:Radioimmunoassay; D013997:Time Factors
D000135:Acid Phosphatase