Immunohistochemical detection of folliculo-stellate cells in human pituitary adenomas.
In the light of recent findings concerning the presence of S-100 antigen in folliculo-stellate cells of the rat adenohypophysis, we investigated the possible presence of S-100-labelled cells in both the normal human adenohypophysis and in pituitary adenomas. Immunostaining enabled us to detect, with both light and electron microscopy, the presence of S-100-labelled folliculo-stellate cells in a significant number of pituitary adenomas, mostly growth-hormone secreting, and, as expected, in the normal human adenohypophysis.
D000236:Adenoma / Q000276:immunology / Q000473:pathology*; D013006:Growth Hormone / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D007158:Immunologic Techniques; D008854:Microscopy, Electron; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000276:immunology; D010911:Pituitary Neoplasms / Q000276:immunology / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis
D009418:S100 Proteins; D013006:Growth Hormone