title: Origin and distribution of cholecystokinin-containing nerve terminals in the lumbar dorsal horn and nucleus caudalis of the cat.
abstract: Immunohistochemical bridge methods were used to localize cholecystokinin (CCK)-like immunoreactivity in the lumbar dorsal horn (DH) and nucleus caudalis (NC) of the cat. The CCK-positive structures were either dot- or fiber-like. The distribution of CCK-like immunoreactivity in the DH and NC was narrower than substance P (SP)-like immunoreactivity in adjacent sections. CCK- and SP-like immunoreactivity in the DH and NC was severely depleted 7--10 days following rhizotomy of either the dorsal roots or the 5th, 9th and 10th cranial nerves, respectively; enkephalin-like immunoreactivity in adjacent sections was unaffected. Cervical hemisection had no effect on either CCK- or SP-like immunoreactivity in the DH.
mesh_terms: D000818:Animals; D002415:Cats; D002421:Caudate Nucleus / Q000166:cytology*; D002766:Cholecystokinin / Q000032:analysis*; D004386:Duodenum / Q000166:cytology; D007118:Immunoassay; D011863:Radioimmunoassay; D013116:Spinal Cord / Q000166:cytology*; D013373:Substance P / Q000032:analysis
chemical_list: D013373:Substance P; D002766:Cholecystokinin