FITC-dextrans as fluorescence and electron microscopic tracers in studies on capillary and cell permeability of the CNS.
FITC-dextrans can be detected at the ultrastructural level as round electron dense particles, with no sign of distortion or aggregation. Because this tracer is a stable, non-toxic polymer of biological origin obtainable in a wide range of molecular weights, it may be useful for further studies of tissue permeability.
D000818:Animals; D002196:Capillaries / Q000648:ultrastructure*; D002463:Cell Membrane Permeability; D002831:Choroid Plexus / Q000098:blood supply* / Q000648:ultrastructure; D003911:Dextrans; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D051379:Mice; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D013861:Thiocyanates
D003911:Dextrans; D005452:Fluoresceins; D013861:Thiocyanates; D016650:Fluorescein-5-isothiocyanate