[Role of virus inhibitory factor or interferon in the antitumoral effect of whole-body hyperthermia].
The interferon inducing effect of hyperthermia was studied in normal and tumor-bearing mice. Circulating interferon was temporarily detected one day after subcutaneous transplantation of 1.6 X 10(6) Ehrlich's ascites tumor cells. Hyperthermia of 43.5 degrees C for 5 min did not induce the interferon formation in mice with or without subcutaneous tumor of the cells. These findings showed that the induction of interferon formation was not main cause of the hyperthermia-induced tumor inhibition.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000628:therapy*; D005260:Female; D005334:Fever / Q000503:physiopathology; D006358:Hot Temperature / Q000627:therapeutic use*; D007372:Interferons / Q000097:blood / Q000502:physiology*; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains
D007372:Interferons
Rôle du facteur inhibiteur des virus ou interféron dans l'effet antitumoral de l'élévation de la température du corps animal.