The evaluation of immune status in children with the past history of obstructive bronchitis.
Selected parametres reflecting cellular and humoral immunity were analyzed in 98, 10 year-old children, who had been hospitalized during first 2 years of life because of bronchitis. In this group, 46 children suffered from obstructive bronchitis and 52 from other types of bronchitis. Serum immunoglobulins, complement components, and antiproteolytic factor levels, T and B lymphocytes counts, leukocyte migration inhibition, and skin tests to PHA and Polyvaccine were compared and analyzed in relation to bronchial obstruction and allergic symptoms in early childhood. The results obtained did not show any significant difference when the group with obstructive type of bronchitis was compared to the rest of children studied. Some differences (increase of the percentage of EAC-FRC and decrease of the levels of the antiproteolytic factors) were noted in relation to allergic symptoms.
D001249:Asthma / Q000276:immunology; D001991:Bronchitis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D012306:Risk; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D002918:Chymotrypsin