The effects of hyperthermia on fast axoplasmic transport in rat sensory fibers.
The fast axoplasmic transport rate increased exponentially with the temperature from 30-45 degrees C. No decline in the fast axoplasmic transport rate was detected during hyperthermic conditions. Hyperthermic conditions induced a decrease in the amplitude of the advancing crest as well as a decline in the slope of the leading edge of the advancing wave in the sciatic nerve. This may suggest that there is a decline in the number of viable fibers transporting the material in these hyperthermic conditions.
D000818:Animals; D001370:Axonal Transport; D006358:Hot Temperature; D007700:Kinetics; D009474:Neurons / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000502:physiology*; D013696:Temperature