Localization of galactocerebroside in oligodendrocytes, myelin sheath and choroid plexus.
The location of galactocerebroside in brain was investigated by using a specific anti-galactocerebroside antibody which was purified by affinity chromatography. It was found that galactocerebroside is distributed not only in oligodendrocytes and myelin but also in epithelial cells of the ependymal layer of the ventricle and choroid plexus. Biochemical analysis also revealed the presence of galactocerebroside and its sulfated derivative, sulfatide, in the choroid plexus.
D000818:Animals; D002554:Cerebrosides / Q000032:analysis*; D002831:Choroid Plexus / Q000032:analysis*; D005699:Galactosylceramides / Q000032:analysis* / Q000276:immunology; D007158:Immunologic Techniques; D009186:Myelin Sheath / Q000032:analysis*; D009457:Neuroglia / Q000032:analysis*; D009836:Oligodendroglia / Q000032:analysis*; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000032:analysis; D013194:Staining and Labeling
D002554:Cerebrosides; D005699:Galactosylceramides; D000254:Sodium-Potassium-Exchanging ATPase