title: Silver-stained accessory structures on human sex chromosomes.
abstract: Using a combination of silver-staining and light microscopic techniques on human male meiotic preparations, it is feasible to study the morphology and behavior of both autosomal synaptonemal complexes and sex chromosome axes. During leptotene and early zygotene, the X and Y chromosomes are separate; their axes appearing as thin, filamentous structures. During late zygotene/early pachytene, the sex chromosomes come close to each other and a distinct sex vesicle is formed. We confirm existence of a short synaptonemal complex between the terminal ends of the X and Y chromosomes. In our preparations, a number of accessory structures can be seen along the axes of the sex chromosomes. These structures appear to be similar in morphology to those previously observed in several other mammalian species.
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008540:Meiosis; D008875:Middle Aged; D009697:Nucleolus Organizer Region; D012730:Sex Chromosomes / Q000648:ultrastructure*; D012835:Silver Nitrate; D013090:Spermatocytes / Q000166:cytology*; D013094:Spermatozoa / Q000166:cytology*; D013194:Staining and Labeling; D014960:X Chromosome / Q000648:ultrastructure; D014998:Y Chromosome / Q000648:ultrastructure
chemical_list: D012835:Silver Nitrate