[Genetics and phenogenetics of the hormonal characteristics of animals. VII. Correlation between brain serotonin and the hypothalamo-pituitary-adrenal system in domesticated and undomesticated silver foxes during emotional stress].
Two groups of silver foxes, selected according their behaviour with respect to man and non-selected ones, were exposed to restriction-induced stress. It was found that changes in the level of brain serotonin and its main metabolite, 5-hydroxyindolacetic acid, and elevation of plasma corticosteroids concentration in domesticated (tame) silver foxes were much less pronounced than in non-domesticated (non-tame) animals. Positive relationship between type of behaviour, brain serotonin metabolism and pituitary-adrenal axis response to stress was observed. It is suggested that such correlative pattern as changed pituitary-adrenal axis responses in domesticated animals may be due to changes in metabolism of controlling this axis brain transmitter serotonin.
D000818:Animals; D000829:Animals, Domestic / Q000235:genetics; D000835:Animals, Wild / Q000235:genetics; D001522:Behavior, Animal / Q000502:physiology; D001923:Brain Chemistry; D005260:Female; D005589:Foxes / Q000235:genetics*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D012641:Selection, Genetic; D012701:Serotonin / Q000032:analysis*; D013315:Stress, Psychological / Q000235:genetics*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid
GEnetika i fenogenetika gormonal'nykh kharakteristik zhivotnykh. VII. Korreliativnaia vzaimosviaz' mezhdu serotoninom mozga i gipotalamo-gipofizarno-nadpochechnikovoĭ sistemoĭ usloviiakh émotsional'nogo stressa u domestitsiruemykh i nedomestitsiruemykh serebristo-chernykh lisits.