Neutralization of heparin by basic proteins of tumor cells: studies in vitro with protein rich in 14C-arginine.
14C-arginine rich basic protein isolated from the cytoplasm of Ehrlich ascites tumor cells neutralizes the anticoagulant of activity heparin. The action of this protein is greater than H3 histone rich in arginine derived from calf thymus.
D000818:Animals; D001120:Arginine / Q000032:analysis*; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis*; D002417:Cattle; D002478:Cells, Cultured; D004591:Electrophoresis, Polyacrylamide Gel; D006494:Heparin Antagonists / Q000032:analysis*; D006657:Histones / Q000032:analysis; D009363:Neoplasm Proteins / Q000494:pharmacology*; D013950:Thymus Gland / Q000032:analysis
D006494:Heparin Antagonists; D006657:Histones; D009363:Neoplasm Proteins; D001120:Arginine