Ketoconazole in a case of chronic mucocutaneous candidiasis.
An 8-year-old girl with chronic mucocutaneous candidiasis was treated with Ketoconazole 100 mg daily for 6 weeks. Oral thrush disappeared after a week, while cutaneous lesions cleared within a month. Her nail dystrophy disappeared during the following months. Repeated cultures were negative for Candida albicans. The patient has remained in remission for an 8-month period. Our findings thus support previous reports indicating that Ketoconazole is an effective agent against this disease.
D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy*; D002178:Candidiasis, Chronic Mucocutaneous / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D007223:Infant; D007654:Ketoconazole; D008213:Lymphocyte Activation; D010879:Piperazines / Q000627:therapeutic use*
D000935:Antifungal Agents; D007093:Imidazoles; D010879:Piperazines; D007654:Ketoconazole