Immunological cross-reactivity between simian virus 40 large T antigen and D2 hybrid T antigen.
A specific antiserum was raised in rabbits against D2 hybrid T antigen that had been purified from HeLa cells infected with the adenovirus/simian virus 40 hybrid, Ad2(+)D2. The specificity of this serum was compared with that of a conventional hamster antiserum against simian virus 40-induced tumors by immunoprecipitation and by a new radioimmune assay that can detect nanogram quantities of D2 hybrid T antigen.
D000260:Adenoviruses, Human / Q000235:genetics / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D000957:Antigens, Viral, Tumor; D003429:Cross Reactions; D000939:Epitopes; D011863:Radioimmunoassay; D011995:Recombination, Genetic; D013539:Simian virus 40 / Q000235:genetics / Q000276:immunology*
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor; D000939:Epitopes