Econazole nitrate in the treatment of candidal vaginitis.
Econazole nitrate (Ecostatin; Squib) in two dosage schedules, 150 mg per day for 3 days and 50 mg per day for 14 days, was found to be extremely effective, with cure rates of 84,9% and 92,4% respectively. As judged by symptomatic and clinical relief, recurrence rates and cure rates according to results of culture, there was no statistically significant difference between the two regimens. On the basis of the results of this trial and because of the advantages it offers, the shorter course can confidently be recommended as the initial treatment in candidal infections.
D000328:Adult; D002176:Candida albicans / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy* / Q000382:microbiology; D004464:Econazole / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D011247:Pregnancy; D012008:Recurrence; D013194:Staining and Labeling; D013997:Time Factors
D007093:Imidazoles; D004464:Econazole