title: Treatment of bladder pain with transsacral nerve block.
abstract: Fifteen patients with bladder spasticity and pain of three different etiologies were referred to the pain clinic by urologic specialists. These patients were refractory to all prior methods of treatment, excluding major surgical procedures. In a prospective study started in 1976, these patients were treated with transsacral nerve blocks using 0.25% bupivacaine and, in most cases, subsequent 6% aqueous phenol at the right S-3 ventral foramen. If indicated, transsacral nerve blocks were performed at other levels, as described in the text. Of the patients studied 53% have had significant or complete relief of pain for an average of 26.5 months. The associated morbidity was negligible and there was no mortality. This is in contrast to the morbidity and mortality associated with some major surgical "curative" procedures. The technique is proposed as a successful and economical approach to treatment that can be managed on an outpatient basis.
mesh_terms: D002045:Bupivacaine / Q000008:administration & dosage; D006801:Humans; D009407:Nerve Block / Q000379:methods*; D010166:Palliative Care; D019800:Phenol; D010636:Phenols / Q000008:administration & dosage; D011446:Prospective Studies; D012445:Sacrococcygeal Region; D001743:Urinary Bladder / Q000294:innervation; D001745:Urinary Bladder Diseases / Q000628:therapy*
chemical_list: D010636:Phenols; D019800:Phenol; D002045:Bupivacaine