IgE-mediated acute asthma following inhalation of a powdered marine sponge.
IgE-antibodies reactive with extracts of a number of different marine invertebrate-species were demonstrated in the serum of a laboratory worker who experienced an acute attack of asthma following occupational exposure to powdered marine-organisms. Histamine was liberated from the patient's blood following in vitro challenge with sponge extract. The desirability of knowing the atopic status of employees in certain occupations is stressed.
D000208:Acute Disease; D000328:Adult; D000485:Allergens; D000818:Animals; D001249:Asthma / Q000209:etiology / Q000276:immunology*; D006636:Histamine Release; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis*; D008297:Male; D009784:Occupational Diseases / Q000209:etiology / Q000276:immunology*; D011161:Porifera / Q000276:immunology*; D011208:Powders; D011852:Radioallergosorbent Test; D011975:Receptors, Mitogen; D012882:Skin Tests
D000485:Allergens; D011208:Powders; D011975:Receptors, Mitogen; D007073:Immunoglobulin E