A light and electron microscopic study of bowenoid papulosis.
Bowenoid papulosis of the genito-anal region was studied by light- and electron-microscopy. Histopathologically there was no difference between bowenoid papulosis and ordinary Bowen's disease. Conspicuous ultrastructural findings included: great variation of intercellular spaces, decrease in intact desmosomes, aggregation of tonofilaments resulting in dyskeratosis, and two types of intracellular vacuolization probably caused by invagination of plasma membrane.
D000328:Adult; D001005:Anus Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D001913:Bowen's Disease / Q000473:pathology* / Q000648:ultrastructure; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D010412:Penile Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D012867:Skin / Q000473:pathology / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D014617:Vacuoles / Q000648:ultrastructure; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000648:ultrastructure