Control of RNA and protein synthesis in phytohemagglutinin-stimulated human lymphocytes by chromatin peptides from calf thymus.
Low molecular weight peptides from calf thymus chromatin inhibit RNA and protein synthesis in Phytohemagglutinin-stimulated human lymphocytes. These results may be correlated to the controlling transcription activity by chromatin peptides in cell-free systems.
D000818:Animals; D001798:Blood Proteins / Q000096:biosynthesis*; D002417:Cattle; D002843:Chromatin / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D010455:Peptides / Q000502:physiology; D010835:Phytohemagglutinins / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis*; D013950:Thymus Gland / Q000378:metabolism*; D014158:Transcription, Genetic
D001798:Blood Proteins; D002843:Chromatin; D010455:Peptides; D010835:Phytohemagglutinins; D012313:RNA