[Effect of 57Co-bleomycetin on the immune response induced in mice by ram erythrocytes].
The effect of 57Co-bleomycin on the  immune response induced by sheep red cells was studied on mice. It was found that the immune response was not suppressed when the labeled antibiotic was used in a single dose of 5-20 mg/kg. By the 5th day the level of 57Co-bleomycin in the skin, thymus and blood was 3-10 times higher than that of 57CoCl2 and in the spleen it was 1.3-1.5 times higher.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000921:Antibody-Producing Cells / Q000187:drug effects; D001761:Bleomycin / Q000276:immunology*; D003037:Cobalt Radioisotopes; D004306:Dose-Response Relationship, Immunologic; D004912:Erythrocytes / Q000276:immunology*; D007114:Immunization; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D012756:Sheep / Q000276:immunology; D013997:Time Factors
D003037:Cobalt Radioisotopes; D001761:Bleomycin
Vliianie 57Co-bleomitsetina na immunnyĭ otvet, indutsirovannyĭ u mysheĭ éritrotsitami barana.