Urinary beta-thromboglobulin in essential hypertension.
Urinary concentrations of the platelet-specific protein beta-thromboglobulin (beta-TG) were measured in patients with essential hypertension. Values obtained for patients with normal renal function fell within the same population as those for a control group of normal individuals, but nevertheless 21% of these patients had urinary beta-TG values above the upper limit of the normal range. Values for patients with renal insufficiency were significantly different from the other groups, and 44% of these individuals had abnormally elevated urinary beta-TG concentrations. These elevated values may reflect an increased plasma concentration of beta-TG in patients with renal impairment or they could be an indicator of renal damage.
D001609:Beta-Globulins / Q000652:urine*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000652:urine*; D007674:Kidney Diseases / Q000150:complications / Q000652:urine; D008297:Male; D001620:beta-Thromboglobulin / Q000652:urine*
D001609:Beta-Globulins; D001620:beta-Thromboglobulin