Polyclonal gammopathy with beta-globulin-gamma-globulin bridging. Two unusual cases.
Polyclonal gammopathy with beta-globulin-gamma-globulin (beta-gamma) bridging has been classically, though not exclusively, described with cirrhosis. We studied two unusual cases that exhibited polyclonal gammopathy with beta-gamma bridging. In the first case, the coexistence of Kaposi's sarcoma appeared with angioimmunoblastic lymphadenopathy. In the second, liver disease developed as a complication of alpha 1-antitrypsin deficiency and retroperitoneal malignant fibrous histiocytoma involving the porta hepatis.
D000368:Aged; D001609:Beta-Globulins; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000276:immunology / Q000473:pathology*; D007119:Immunoblastic Lymphadenopathy / Q000150:complications; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D012514:Sarcoma, Kaposi / Q000150:complications; D005719:gamma-Globulins
D001609:Beta-Globulins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005719:gamma-Globulins