Factors affecting plasma beta-thromboglobulin in diabetes mellitus.
Plasma beta-thromboglobulin, hemoglobin A1c and serum creatinine were measured in 56 diabetic patients. Patients with diabetic complications had a significantly higher beta-thromboglobulin level than the controls, but patients without complications did not differ from the controls. beta-Thromboglobulin correlated positively with serum creatinine and the highest values were encountered in patients with abnormal creatinine concentration. There were, however, patients with normal creatinine but high plasma beta-thromboglobulin levels. In these patients the abnormal beta-thromboglobulin level most probably indicates undue stimulation of platelets. There was no correlation between beta-thromboglobulin and hemoglobin A1c.
D000328:Adult; D000368:Aged; D001609:Beta-Globulins / Q000032:analysis*; D003404:Creatinine / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood*; D003925:Diabetic Angiopathies / Q000097:blood; D005260:Female; D006027:Glycosides / Q000032:analysis; D006441:Hemoglobin A / Q000031:analogs & derivatives / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D001620:beta-Thromboglobulin / Q000032:analysis*
D001609:Beta-Globulins; D006027:Glycosides; D001620:beta-Thromboglobulin; D006441:Hemoglobin A; D003404:Creatinine