title: Subacute sclerosing panencephalitis antibodies against measles virus polypeptides.
abstract: Antibodies to measles virus proteins in SSPE, MS and control human sera were compared using measles virus strain Edmonston, productive SSPE strain Mantooth and non-productive SSPE strain DR. The viral antigens were subjected to transfer electrophoresis, incubated with sera and localized after a second incubation with peroxidase labeled immunoglobulins. High levels of antibodies to all measles viral proteins are present in SSPE sera and CSF and to a lesser degree in MS and control sera although the non-productive SSPE strains lack one viral protein (M protein) present in wild type measles virus strains and the productive SSPE strains.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology; D002417:Cattle; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D004586:Electrophoresis / Q000379:methods; D006801:Humans; D008457:Measles / Q000276:immunology; D008459:Measles virus / Q000276:immunology*; D010455:Peptides / Q000276:immunology; D013190:SSPE Virus / Q000276:immunology*; D013344:Subacute Sclerosing Panencephalitis / Q000276:immunology; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D010455:Peptides; D014763:Viral Matrix Proteins; D014764:Viral Proteins