[An interesting case of defective HLA phenotype].
In a 27 years old man whose parents had HLA phenotypes A 9/B 7, Bw 16 and Al/B 17, B 18 only HLA-B 18 could be reliably identified in lymphocytes by means of microlymphocytotoxic tests. It is probable that HLA-Bw 16 was also present in the lymphocytes of this test person. Even by applying the neutralisation test, the HLA antigens A 1 and a 9 could not be detected in the test person's serum. The cause for the existence of the defective HLA phenotype is discussed.
D000328:Adult; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005826:Genetics, Medical; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D009500:Neutralization Tests; D010641:Phenotype
D006680:HLA Antigens
Ein interessanter Fall eines defekten HLA-Phänotyps.