[Early therapy with immunoglobulins after extensive abdominal operations. A random study (author's transl)].
A random study with 100 patients was conducted to show whether the immunoglogulin Gamma Venin, when given after rectum extirpation, has an effect on wound healing and other infections. The patients in the test group received 10 g of Gamma Venin within the first 48 h after surgery. The number of days with purulent wound secretion were reduced to 0.71 (test group) as opposed to 7.61 (control) with statistical significance. Primary wound healing was 37% in the test group and 9% in the control group (P < 0.01). Other infections occurred in a similar range. The time of hospitalization was 3.44 days less than in the test group (P < 0.01).
D000005:Abdomen / Q000601:surgery*; D002986:Clinical Trials as Topic; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use*; D007902:Length of Stay; D011897:Random Allocation; D012007:Rectum / Q000601:surgery; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000188:drug therapy*; D005719:gamma-Globulins / Q000627:therapeutic use*
D007140:Immunoglobulin Fab Fragments; D005719:gamma-Globulins
Die Frühtherapie mit Immunglobulinen nach grossen abdominalchirurgischen Eingriffen. Eine prospektive randomisierte Studie.