title: Microcarriers for animal cell culture: a brief review of theory and practice.
abstract: Microcarrier beads for animal cell culture are considered in relation to aspects of cell adhesion and growth. Some "critical parameters" for a successful microcarrier are discussed, comparing currently available materials. The properties most critical for a successful microcarrier were closely fulfilled by the microcarrier CytodexTM 1 which has been used for the successful cultivation of more than 60 different cell types. Cytodex 1 has been used for the culture of primary cells, normal diploid cell strains and established or transformed cell lines in culture volumes ranging from a few millilitres to over 100 litres.
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002455:Cell Division; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured / Q000166:cytology*; D003584:Cytological Techniques; D003637:DEAE-Dextran; D003911:Dextrans; D006801:Humans
chemical_list: D003911:Dextrans; D003637:DEAE-Dextran