[Detection of a common antigenic determinant in the major inner protein of unrelated oncoviruses].
A new heterologous system of radioimmunoassay (p24 of bovine leukemia virus--antiserum to Rous sarcoma virus) has been developed which demonstrated for the first time the existence of a common antigenic determinant in the major inner protein of unrelated oncoviruses: avian leukemia-sarcoma virus, bovine leukemia virus, mammalian type C viruses (mouse, hamster, monkey) and type D viruses (simian Mason-Pfizer virus). These data suggest a common origin of unrelated oncoviruses and open new approaches for the search of unknown agents associated with human and animal neoplastic diseases.
D001355:Alpharetrovirus / Q000276:immunology; D000818:Animals; D001358:Avian Sarcoma Viruses / Q000276:immunology; D000939:Epitopes; D006801:Humans; D009369:Neoplasms / Q000209:etiology / Q000662:veterinary; D009858:Oncogenic Viruses / Q000276:immunology*; D012190:Retroviridae / Q000276:immunology
D000939:Epitopes
Vyiavlenie obshcheĭ antigennoĭ determinanty v glavnom vnutrennem belke nerodstvennykh onkovirusov.