A study of human-type ABH antigens on erythrocytes and in saliva of sheep.
The results of serological investigations of human type ABH antigens and antibodies of 116 sheep are presented. Traces of ABH antigens on sheep erythrocytes are recognized by elution. Agglutinins with anti-AA1, anti-B and sometimes anti-H specificity besides of heteroagglutinins were differentiated by cross-absorption experiments. It was established that the sheep saliva also contains H antigens and sometimes A and/or A1 antigens. On the basis of their serological characteristics the sheep divided into 11 serological groups. In order to explain some serological peculiarities in sheep the existence of genes for regulation, the production of ABH antigens in glucolipid form and genes for regulation of the same antigens in glucoprotein form were postulated.
D000017:ABO Blood-Group System / Q000235:genetics / Q000276:immunology*; D000372:Agglutination Tests; D000818:Animals; D001788:Blood Grouping and Crossmatching; D004912:Erythrocytes / Q000276:immunology*; D005809:Genes, Regulator; D006801:Humans; D007519:Isoantigens / Q000276:immunology*; D012463:Saliva / Q000276:immunology*; D012756:Sheep / Q000276:immunology*; D013045:Species Specificity
D000017:ABO Blood-Group System; D007519:Isoantigens