Axonal transport in the central axon of sensory neurons during regeneration of their peripheral axon.
Following sciatic nerve injury (which provokes prompt regeneration of peripheral sensory axons) there was no change in the ratio between amounts of labeled protein conveyed by fast axonal transport into the central and peripheral axons. A change in composition of the transported protein, characteristic of regenerating peripheral axons, also occurred in the central axons. When the peripheral axon is injured, changes in axonal transport thus affect both processes, and there is no routing of fast-transported protein into or away from the regenerating process.
D000818:Animals; D001370:Axonal Transport; D001369:Axons / Q000502:physiology*; D008297:Male; D009416:Nerve Regeneration; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009475:Neurons, Afferent / Q000378:metabolism* / Q000502:physiology; D051381:Rats; D012584:Sciatic Nerve / Q000293:injuries
D009419:Nerve Tissue Proteins