title: Intranasal steroid injection during pregnancy.
abstract: Nasal obstruction during pregnancy may arise from allergic or endocrine factors and often compounded by abuse of topical nasal vasoconstrictors. Severe nasal symptoms occurred in 32% of pregnant women surveyed. Despite self-medication with nose drops and proprietary remedies, as well as prescriptions of antihistamines and systemic decongestants, some instances of rhinitis of pregnancy remain refractory to treatment. Intranasal injection of corticosteroids affords rapid and lasting relief for these patients. In this series, 21 patients with severe nasal obstruction during pregnancy received 27 intranasal steroid injections. Excellent relief of symptoms was obtained, without untoward effects on the pregnancy.
mesh_terms: D004487:Edema / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007267:Injections / Q000379:methods; D009297:Nasal Mucosa; D009666:Nose; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012220:Rhinitis / Q000188:drug therapy*
chemical_list: D005938:Glucocorticoids