title: Fetal perfusion with maternal blood; a possible sequel to fetal catheterization in the pig.
abstract: Plasma gamma-globulin concentrations were increased in three catheterized pig fetuses in which the packed red cell volume rose rapidly after surgery, but were not increased in one fetus in which the packed cell volume remained normal. The increases in packed cell volume and gamma-globulin concentration were closely correlated. The source of the gamma-globulin was investigated in one sow with catheterized fetuses. Maternal proteins, identified by [125I]-labelling and gel diffusion, crossed to the circulation of the one catheterized fetus with an elevated packed cell volume but not to the other, in which packed cell volume remained normal, nor to two unoperated fetuses. The results suggest that vascular anastmosis between fetal and maternal circulations is a possible sequel to cannulation in this species.
mesh_terms: D000818:Animals; D002404:Catheterization / Q000009:adverse effects / Q000662:veterinary*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006400:Hematocrit / Q000662:veterinary*; D005779:Immunodiffusion; D008431:Maternal-Fetal Exchange; D010477:Perfusion; D011247:Pregnancy; D013552:Swine / Q000097:blood*; D005719:gamma-Globulins / Q000378:metabolism*
chemical_list: D005719:gamma-Globulins