[Dependence between the rate of RNA synthesis and the CTP-synthetase activity of different rat and chicken tissue].
The rate of total RNA synthesis determined by the method of Bukher and Sheffield in different tissues of rats and chickens decreases as follows: kidneys greater than liver greater than duodenum mucosa. The activity of CTP-synthetase (EC 6, 3, 4, 2) determined in vitro and in vivo by the method suggested correlates with the rate of total RNA synthesis in the kidneys and liver tissues of rats and chickens. It is shown that 34-35% of CTP synthetized de novo in the chicken tissues and 31-34% in the rat tissues are used for RNA synthesis. At the same time 75-90% of CTP incorporating into RNA is formed by salvage pathway.
D000818:Animals; D019731:Carbon-Nitrogen Ligases; D002645:Chickens; D004386:Duodenum / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D007700:Kinetics; D008025:Ligases / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D009928:Organ Specificity; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D012313:RNA; D008025:Ligases; D019731:Carbon-Nitrogen Ligases; C019951:CTP synthetase
Zavisimost' mezhdu skorost'iu sinteza RNK i aktivnost'iu CTP-syntetazy v razlichnykh tkaniakh krys i tsypliat.