Hemoglobin F production in testicular malignancy.
The peripheral blood of 3 patients with testicular malignancy and elevated hCG levels was examined for Hb F production. Increases of percent chemically determined Hb F and/or F cell number were observed in each case when or soon after the hCG level was elevated. In these cases, Hb F production correlated with the degree of clinically evident malignancy. These observations suggest that the reactivation of Hb F synthesis may be applied to the evaluation of disease activity in patients with testicular malignancy.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D004906:Erythrocyte Count; D005319:Fetal Hemoglobin / Q000378:metabolism*; D006801:Humans; D008297:Male; D012156:Reticulocytes; D013736:Testicular Neoplasms / Q000097:blood*
D006063:Chorionic Gonadotropin; D005319:Fetal Hemoglobin