Sleep and low doses of alcohol.
The effect of 3 doses of alcohol (0.16, 0.32 and 0.64 g/kg) on sleep was studied in 6 healthy young adults. Total sleep time was increased and awake activity was reduced by 0.16 g/kg. The sleep efficiency index was improved by 0.16 and 0.32 g/kg. All 3 doses reduced slow wave sleep, and this was related to the latter part of the night. There was some evidence that REM sleep was delayed, and the REM/NREM ratio reduced. Low doses of alcohol may partially improve sleep, but there are reductions in slow wave activity, and disturbances in REM sleep are likely above 0.32 g/kg.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010919:Placebos; D012890:Sleep / Q000187:drug effects*; D012894:Sleep Stages / Q000187:drug effects; D013997:Time Factors
D010919:Placebos; D000431:Ethanol