Per operative trypan blue vital staining of corneal endothelium. Eight years' follow up.
An 0.1% aqueous trypan blue solution was injected into the anterior chamber during cataract extraction for the purpose of disclosing endothelial cell damage if present. Follow-up examination of 24 patients after eight years revealed no side-effects of trypan blue, as judged by corneal opacities, compared with non-vital-stained aphakic and non-operated control eyes.
D000368:Aged; D000867:Anterior Chamber; D002387:Cataract Extraction; D003315:Cornea / Q000187:drug effects* / Q000473:pathology; D004727:Endothelium / Q000187:drug effects / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D013194:Staining and Labeling; D013997:Time Factors; D014343:Trypan Blue / Q000008:administration & dosage / Q000633:toxicity
D014343:Trypan Blue