Spleen immunomorphologic behaviour in primary and secondary acute bronchopulmonary inflammations of children. Comparative analysis of the lung and hilar-tracheobronchial lymph nodes' reactions.
The spleens sampled at necropsy of 221 children with acute primary and secondary bronchopulmonary inflammations were characterized by the hyperplasia of lymphoid follicles and plasma cells in 37 per cent of the cases, only a few of them with a multilayered organization of follicles, and by lymphoid depletion in 19 per cent of the cases. The remainder presented small unorganized lymphoid follicles of the primary type, some cases being remarkable by their nodules with a "core" of "epithelioid pattern". The pyroninophilic reactions of high intensity were preponderant in bronchopneumonia of the primary type, but unlike the lung and hilar-tracheobronchial lymph nodes, in spleen there were no differences concerning the two value groups of reactions between the primary pneumonia cases with or without associated extrapulmonary inflammations. Immunofluorescence evidenced, in decreasing order, all the three classes of immunoglobulins: IgM, IgG and IgA.
D000208:Acute Disease; D000293:Adolescent; D001996:Bronchopneumonia / Q000473:pathology / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005455:Fluorescent Antibody Technique; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D008198:Lymph Nodes / Q000473:pathology*; D013154:Spleen / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology; D013194:Staining and Labeling
D007136:Immunoglobulins