Blood-borne stem cells are immunologically distinct from those in other hematopoietic tissues.
The effects of rabbit anti-mouse brain serum on marrow, spleen, and blood CFUs were assessed. The results suggest a clear immunologic distinction between blood vs. other CFUs. It is suggested that this difference may be a consequence of cellular differentiation or aging.
D000328:Adult; D000818:Animals; D000954:Antigens, Surface; D001773:Blood Cells / Q000276:immunology; D001854:Bone Marrow Cells; D001921:Brain / Q000276:immunology; D002452:Cell Count; D002454:Cell Differentiation; D002470:Cell Survival; D000939:Epitopes; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D011817:Rabbits / Q000276:immunology; D013154:Spleen / Q000166:cytology
D000954:Antigens, Surface; D000939:Epitopes; D007106:Immune Sera