[Mechanism of interferon action on expression of SV40 virus genome during lytic infection (a hypothesis)].
On the basis of analysis of literary data it is suggested that the inhibitory action of interferon on the SV40 reproduction is connected with the disturbance of splicing of primary transcripts by 2'-5'-oligoadenylates.
D001483:Base Sequence; D004722:Endoribonucleases / Q000378:metabolism; D004789:Enzyme Activation; D005786:Gene Expression Regulation; D005814:Genes, Viral; D007372:Interferons / Q000494:pharmacology*; D014176:Protein Biosynthesis / Q000187:drug effects; D012326:RNA Splicing / Q000187:drug effects; D012333:RNA, Messenger / Q000235:genetics; D012367:RNA, Viral / Q000235:genetics; D013539:Simian virus 40 / Q000235:genetics* / Q000276:immunology / Q000502:physiology; D014158:Transcription, Genetic / Q000187:drug effects
D012333:RNA, Messenger; D012367:RNA, Viral; D007372:Interferons; D004722:Endoribonucleases; C021885:ribonuclease F
Mekhanizm deĭstviia interferona na ékspressiiu genoma virusa SV40 pri liticheskoĭ infektsii (gipoteza).