title: Substance P in the central nervous system.
abstract: A radioimmunoassay has been developed for measuring substance P-like immunoreactivity. Assay sensitivity was 0.7fmoles of substance P. Using the radioimmunoassay substance P-like immunoreactivity was detected in postmortem tissue samples from the central nervous system of rats and humans. Immunofluorescence studies confirmed the localisation of substance P in the dorsal horn of the spinal cord.
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000032:analysis*
chemical_list: D013373:Substance P