The role of interferon induction in the interferon sensitivity of the mengovirus mutant, is-1.
An interferon-sensitive mutant of mengovirus has been shown to specifically induce interferon in infected cells. Although this appears to account for the sensitivity to interferon observed by others in an L(Y) cell line, it cannot account for the even greater sensitivity observed in our G3 line of mouse L cells.
D000818:Animals; D000906:Antibodies / Q000276:immunology; D002999:Clone Cells / Q000382:microbiology; D007372:Interferons / Q000096:biosynthesis* / Q000276:immunology / Q000494:pharmacology; D007739:L Cells / Q000382:microbiology; D008574:Mengovirus / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D009154:Mutation
D000906:Antibodies; D007372:Interferons