The effect of surgery on the renal excretion of beta 2-microglobulin.
Surgical trauma causes an increase in the renal excretion rate of beta 2-microglobulin whilst creatinine excretion is not influenced. The increase in the renal excretion rate of beta 2-microglobulin is probably the result of an increased release of beta 2-microglobulin by the cells which exceeds a maximum in the active tubular reabsorption of the compound by the proximal tubule cell. The renal excretion of beta 2-microglobulin is proportional to the relative clinical trauma score.
D001609:Beta-Globulins / Q000652:urine*; D003404:Creatinine / Q000652:urine; D004231:Diuresis; D006801:Humans; D007700:Kinetics; D013514:Surgical Procedures, Operative; D001613:beta 2-Microglobulin / Q000652:urine*
D001609:Beta-Globulins; D001613:beta 2-Microglobulin; D003404:Creatinine