51Cr-bleomycin in the diagnosis of ocular melanoma.
51Cr-bleomycin was administered to 18 patients suspected of having an ocular melanoma with varying degree of development. The diagnosis was verified prior to surgical removal of the eye-ball by fluorescent angiography and computerized axial tomography. In operated patients histological diagnosis was also available. Scintigraphy after 51Cr-bleomycin administration appeared to be an effective diagnostic measure: sensitivity and specificity reached 90 and 87%, respectively. It is concluded that the method is useful in the preoperative diagnosis of ocular melanoma.
D000328:Adult; D000368:Aged; D001761:Bleomycin; D002860:Chromium Radioisotopes; D005134:Eye Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging*; D008875:Middle Aged; D011877:Radionuclide Imaging
D002860:Chromium Radioisotopes; D001761:Bleomycin