6-Hydroxy-5-methoxyindole-2-carboxylic acid in normal human urine.
The presence of 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI-2-C) in normal human urine was demonstrated by mass spectrometry. A quantitative method based on HPLC with fluorometric detection was developed for the determination of 6H5MI-2-C. In normal subjects the mean urinary concentration of 6H5MI-2-C was 38 mumol/mol of creatinine (range 6-76 mumol/mol).
D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007211:Indoles / Q000652:urine*
D007211:Indoles; C017408:6-hydroxy-5-methoxy-2-indolylcarboxylic acid