[Elevation of the serum concentration of alpha- and beta-globulins and of a particular carcinoembryonic antigen by ultrasound exposure of liver tissue and CEA-active carcinomas].
The concentration of alpha- and beta-globulins in the serum can be increased by exposure of the globulin-producing tissue of the liver to ultrasound. The ultrasound intensities producing this effect are harmless according to our present knowledge. Especially the concentration of the globulin carcinoembryonic antigen in the serum can be increased significantly by exposure of CEA-producing carcinomas to ultrasound. There is to investigate the possibility of the early detection of CEA-producing tumors using a provocation test by way of increasing still normal spontaneous CEA-concentrations in the serum by insonation of body regions in question to significant pathologic serum concentrations.
D000510:Alpha-Globulins / Q000032:analysis* / Q000528:radiation effects; D001609:Beta-Globulins / Q000032:analysis* / Q000528:radiation effects; D002272:Carcinoembryonic Antigen / Q000032:analysis* / Q000528:radiation effects; D002277:Carcinoma / Q000097:blood / Q000175:diagnosis* / Q000556:secondary; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis / Q000556:secondary; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000097:blood / Q000175:diagnosis / Q000556:secondary; D014465:Ultrasonics / Q000009:adverse effects; D014463:Ultrasonography
D000510:Alpha-Globulins; D001609:Beta-Globulins; D002272:Carcinoembryonic Antigen
Die Steigerung der Serumkonzentration von alpha- und beta-Globulinen und speziell des karzinoembryonalen Antigens durch Ultraschallbestrahlung von Lebergewebe bzw. von CEA-aktiven Karzinomen.