Examination of placental proteins in charge-shift immunoelectrophoresis.
Three pregnancy-associated proteins, pregnancy-specific beta1-glycoprotein (SP-I), pregnancy-associated plasma protein A(PAPP-A), and placental lactogen (hPL) were examined by charge-shift immunoelectrophoresis. PAPP-A and hPL exhibited hydrophilic properties whereas SP-I was amphiphilic. These observations suggest that SP-I is a cell membrane protein.
D003902:Detergents; D005260:Female; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional / Q000379:methods; D010920:Placenta / Q000032:analysis* / Q000276:immunology; D010928:Placental Lactogen / Q000032:analysis*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis*
D003902:Detergents; D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins; D010928:Placental Lactogen; D011266:Pregnancy-Associated Plasma Protein-A