title: [Comparative evaluation of the specific activity of different types of allergens from Dermatophagoides pteronyssinus mites].
abstract: The specific activity of different kinds of allergens prepared from dermatophagoid mites has been studied by the method of the indirect mast cell degranulation and the method of changing the volume of cerebral glial cells in patients with the atopic form of bronchial asthma. In cases of sensitization to mites the presence of reagin and precipitin antibodies has been revealed. Allergens prepared from the mite medium and directly from mites have been found to possess almost the same specific activity. Changes in the volume of glial cells have been found to serve as a sensitive test revealing the specific activity of mite allergens.
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D001249:Asthma / Q000276:immunology; D001921:Brain / Q000276:immunology; D004391:Dust; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D008407:Mast Cells / Q000276:immunology; D008925:Mites / Q000276:immunology*; D009457:Neuroglia / Q000276:immunology; D051381:Rats
chemical_list: D000485:Allergens; D004391:Dust; D000939:Epitopes
vernacular_title: Sravnitel'naia otsenka spetsificheskoĭ aktivnosti razlichnykh vidov allergenov iz kleshcheĭ Dermatophagoides pteronyssinus.