The changes of serum titers of thyroid antibodies in patients of Graves' disease with hyperthyroidism after treatments with antithyroid drugs.
In order to investigate the effect of antithyroid drugs on serum titers of antithyroglobulin and anti-thyroid microsomal antibody, these two antibody levels were studied in 38 patients of Graves' disease with hyperthyroidism before and after treatments with carbimazole or methimazole. The results showed no consistent changes in their titers. To explain the inconsistent findings as compared with other authors' studies, lower doses of antithyroid drugs were postulated as one of the causes.
D000293:Adolescent; D000328:Adult; D013956:Antithyroid Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D006111:Graves Disease / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008297:Male; D008861:Microsomes / Q000276:immunology; D008875:Middle Aged; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology*
D013956:Antithyroid Agents; D001323:Autoantibodies; D007166:Immunosuppressive Agents; D013954:Thyroglobulin