Etiopathogenesis of Meniere's disease: a hypothesis.
A new hypothesis of etiopathogenesis of Meniere's disease proposes that an autoimmune response to type II collagen could induce idiopathic endolymphatic hydrops. This hypothesis is extended to provide a rational explanation for Meniere's attacks.
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D003094:Collagen / Q000276:immunology*; D007758:Ear, Inner / Q000276:immunology; D004710:Endolymph / Q000276:immunology; D004711:Endolymphatic Duct / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D006801:Humans; D007124:Immunoenzyme Techniques; D008575:Meniere Disease / Q000209:etiology* / Q000276:immunology
D000906:Antibodies; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D000939:Epitopes; D003094:Collagen