A heat polyethylene glycol procedure as an alternative method for plasmafractionation.
Polyethylenglycol 4000 was used in a combined process of fractionation at normal temperature for preparing gammaglobulin and albumin in a heat denaturation process. Albumin can be gained from human plasma with a high yield and purity by using a heat procedure at the presence of polyethylglycol 4000 and sodium octanate at 75 degrees C. The concentration of polyethylglycol 4000 varies during this heat procedures from 3-10% W/V.
D005591:Chemical Fractionation / Q000379:methods; D006358:Hot Temperature; D006801:Humans; D011092:Polyethylene Glycols; D012709:Serum Albumin / Q000302:isolation & purification*
D012709:Serum Albumin; D011092:Polyethylene Glycols