Regional distribution of kassinin-like immunoreactivity in rat central and peripheral tissues and the effect of capsaicin.
The regional distribution of kassinin-like immunoreactivity in rat central and peripheral tissues was investigated by radioimmunoassay and found to resemble closely that of substance P-like immunoreactivity. Neonatal capsaicin treatment caused a similar decrease to both kassinin-like and substance P-like immunoreactivity in primary sensory areas. These results suggest that more than one member of the tachykinin family of neuropeptides exist within the same neuron.
D000818:Animals; D000831:Animals, Newborn; D002211:Capsaicin / Q000494:pharmacology*; D002490:Central Nervous System / Q000378:metabolism; D005260:Female; D015286:Kassinin; D008297:Male; D009420:Nervous System / Q000378:metabolism*; D009842:Oligopeptides / Q000378:metabolism*; D010525:Peripheral Nerves / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000378:metabolism
D009842:Oligopeptides; D013373:Substance P; D015286:Kassinin; D002211:Capsaicin