Recurrent anaphylactic reaction to intraperitoneal dextran 75 used for prevention of postsurgical adhesions.
The use of intraperitoneal dextran at the conclusion of a gynecologic surgical procedure to prevent postoperative adhesions has increased recently. Although anaphylactic reaction to dextran administered intravenously is well documented, the authors report such a reaction after intraperitoneal administration. The delayed appearance and the continuation of the undesirable reaction until the intraperitoneal reservoir of dextran was removed by means of a culdocentesis are noteworthy. Physicians should be alerted to this potential complication.
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D003911:Dextrans / Q000009:adverse effects*; D005260:Female; D005831:Genital Diseases, Female; D006801:Humans; D010532:Peritoneal Diseases / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control; D012008:Recurrence; D000267:Tissue Adhesions / Q000517:prevention & control
D003911:Dextrans