When is there a full recovery for a myasthenia gravis patient?
A myasthenia gravis (MG) patient who seems to have recovered can later have recurrence of myasthenic signs. Clearly clinical remission does not always correspond to the normalization of all the factors involved in the pathogenesis of the disease. In ten patients who had apparently recovered from MG, electromyographic tests of repetitive supramaximal stimulation were performed and the anti-acetylcholine receptor (anti-AChR) antibody was assessed. In two of the ten patients all these tests were normal, thus showing lack of electromyographic myasthenic fatigability and the absence of circulating anti-AChR antibodies. Our hypothesis is that for these two subjects the risk of a recurrence of MG is lower than for the others.
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000276:immunology / Q000628:therapy*; D009431:Neural Conduction; D011950:Receptors, Cholinergic / Q000276:immunology; D012008:Recurrence; D012306:Risk; D013934:Thymectomy
D001323:Autoantibodies; D011950:Receptors, Cholinergic