title: Combined electrophysiological assessment of the visual system in central serous retinopathy.
abstract: Six subjects suffering from idiopathic central serous retinopathy were examined during the acute phase using a battery of neurophysiological tests. The records (using skin electrodes) included the electro-oculogram (EOG), the white light electroretinogram (ERG) during various stages of dark and light adaptation, and the flash and pattern reversal visual evoked potentials. Results obtained from the affected eye were compared with those from the healthy eye. The values of the healthy eye were not significantly different from our normal control group. The EOGs of the affected eyes were not significantly different from those of the healthy eyes. The 'a' wave of the ERG during light adaptation was significantly (P less than 0.05) smaller in the affected eye. The amplitudes of the other components and the latencies of all components were not affected. The latency of the PR-VEP of the affected eye in all subjects was prolonged in comparison with the unaffected eye. In 3 subjects the latency was prolonged by more than 2 S.D.s compared with our control group. The amplitude of the PR-VEP in 5 of our 6 subjects was slightly but significantly (P less than 0.02) smaller in the affected eye. There was no correlation between amplitude and latency changes.
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D003623:Dark Adaptation; D004585:Electrooculography; D004594:Electrophysiology; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005123:Eye / Q000503:physiopathology*; D006801:Humans; D010364:Pattern Recognition, Visual; D012164:Retinal Diseases / Q000503:physiopathology*