Subretinal neovascularization in senile macular degeneration.
When fluorescein angiograms from 563 patients with senile macular degeneration examined at a large community hospital during a 9.5-year period were retrospectively reviewed, 200 patients were found to have a dry atrophic type of senile macular degeneration, consisting of drusen and retinal pigment epithelial changes. Of the 363 patients with exudative senile macular degeneration, 244 had subretinal neovascular membranes. Seventy-eight membranes were less than 1 disk diameter in size. Most of the large (157 of 224) and small (44 of 78) membranes showed a predilection for the fovea. Only 13 large and six small neovascular membranes were 200 microns or more from the center of the foveal avascular zone.
D005451:Fluorescein Angiography; D006801:Humans; D008028:Light Coagulation; D008268:Macular Degeneration / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D009389:Neovascularization, Pathologic / Q000209:etiology* / Q000473:pathology; D012160:Retina / Q000098:blood supply*; D012189:Retrospective Studies; D014792:Visual Acuity