title: Cardiovascular effects of various colloidal solutions during major abdominal surgery.
abstract: We examined the effects of various colloidal solutions on cardiovascular and oxygen transport variables for 26 patients undergoing gastrectomy under general anesthesia. Fluosol-DA, whole blood, 3% Dextran-40 (Saviosol), and 6% hydroxyethyl starch (hetastarch, Hespan) affected the right side of heart, but only whole blood and Fluosol-DA significantly increased cardiac output and oxygen delivery (DO2). Fluosol-DA may prove useful for critical care of hemorrhagic shock during operation or resuscitation in the immediate postoperative period.
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D001802:Blood Substitutes / Q000627:therapeutic use*; D002302:Cardiac Output / Q000187:drug effects; D003102:Colloids; D003911:Dextrans / Q000627:therapeutic use*; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use*; D005743:Gastrectomy; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000187:drug effects*; D013213:Starch / Q000031:analogs & derivatives*
chemical_list: D001802:Blood Substitutes; D003102:Colloids; D003911:Dextrans; D004338:Drug Combinations; D005466:Fluorocarbons; D006895:Hydroxyethyl Starch Derivatives; C017323:glucose, glycerol, hydroxyethyl starch, perfluorodecalin, perfluorotripropylamine, pluronic F-68, salts, yolk phospholipids drug combination; D013213:Starch