Effect of a mild dose of X-irradiation on rats under stress.
This investigation was apt at studying the effect of a mild dose of X-rays on the normal and shock administered rats. Administration of stress brought about a marked depression in the contents of DNA, RNA and protein in the brain. On the other hand, total body exposure to X-rays was found to increase the levels of DNA, RNA and protein in the brain. Thus, the use of a mild dose of X-rays in stressed animals seems to be stimulatory to the diminished levels of DNA, RNA and protein in the brain. There were rising levels of 5-hydroxy indol acetic acid and Vinyl mandelic acid in the urine of stress administered rats and the enhanced levels of these urinary metabolites appeared to be refractory to the application of X-rays.
D000818:Animals; D001921:Brain / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000096:biosynthesis; D005260:Female; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D009419:Nerve Tissue Proteins / Q000096:biosynthesis; D012313:RNA / Q000096:biosynthesis; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism / Q000532:radiotherapy*; D014642:Vanilmandelic Acid / Q000652:urine
D009419:Nerve Tissue Proteins; D006897:Hydroxyindoleacetic Acid; D014642:Vanilmandelic Acid; D012313:RNA; D004247:DNA