title: [Morphofunctional characteristics of changes in the exocrine portion of the pancreas in alimentary obesity].
abstract: Changes in the morpho-functional state and intracellular regeneration of the exocrinous part of the pancreatic gland in alimentary obesity were studied experimentally in rats. Systematic alimentary overloading of the pancreatic gland was found to lead to working hypertrophy of its "reserve" parts predominantly which are represented in females by tail parts of the gland and in males by the head. It is suggested that the lower regeneratory potential of the acinary cells and their greater predisposition to degenerative, necrobiotic, and necrotic changes with the progress of obesity in males may be due to greater intensity of organ vascular pathology in them and greater sensitivity of acinary cells to metabolic disorders.
mesh_terms: D000818:Animals; D005260:Female; D006984:Hypertrophy; D008297:Male; D009336:Necrosis; D009765:Obesity / Q000378:metabolism / Q000473:pathology*; D010179:Pancreas / Q000378:metabolism / Q000473:pathology*; D012313:RNA / Q000378:metabolism; D051381:Rats; D012737:Sex Factors
chemical_list: D012313:RNA
vernacular_title: Morfofunktional'naia kharakteristika izmeneniĭ vneshnesekretornogo otdela podzheludochnoĭ zhelezy pri alimentarnom ozhirenii.