The multiplicity of domains on a protein antigen affecting immune responsiveness.
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D005802:Genes, MHC Class II; D006183:H-2 Antigens / Q000276:immunology; D009113:Muramidase / Q000276:immunology; D011487:Protein Conformation; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000939:Epitopes; D006183:H-2 Antigens; D009113:Muramidase