title: [Spontaneous variations in the characteristics of ventricular extrasystole].
abstract: The authors studied 65 patients (mainly with chronic coronary heart disease) with 48 hours of continuous two-channel Holter recordings of antiarrhythmic drugs. Spontaneous qualitative day to day variations in ventricular premature beats (VPB) exceeding 50% were recorded in 22 (33.8%) cases, those exceeding 75%--in 10 (15.4%) cases. Additional cases of severe Lown grade VPB during the second day of monitoring were revealed in 8 (12.3%) cases. We conclude, that marked day to day variation in VPB require a strict criterion (greater than 75% decrease) to define antiarrhythmic drug efficacy.
mesh_terms: D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000592:standards; D005117:Cardiac Complexes, Premature / Q000175:diagnosis* / Q000188:drug therapy; D004341:Drug Evaluation / Q000379:methods; D004562:Electrocardiography / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic
chemical_list: D000889:Anti-Arrhythmia Agents
vernacular_title: O spontannykh kolebaniiakh kharakteristik zheludochkovoĭ ékstrasistolii.