title: Septicemia and lung injury.
abstract: The results of investigations undertaken by the authors which deal with the functional and structural changes in the lungs resulting from gram-negative bacterial endotoxemia and the mechanisms of these changes are analyzed. The authors emphasize the major roles played by granulocytes and metabolites of arachidonic acid in mediating endotoxin-induced lung injury.
mesh_terms: D000328:Adult; D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism; D001792:Blood Platelets / Q000502:physiology; D002417:Cattle; D004927:Escherichia coli Infections / Q000150:complications; D006098:Granulocytes / Q000276:immunology / Q000473:pathology; D006636:Histamine Release; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000503:physiopathology*; D011654:Pulmonary Edema / Q000209:etiology; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D018805:Sepsis / Q000150:complications / Q000276:immunology / Q000503:physiopathology*; D012756:Sheep; D012772:Shock, Septic / Q000150:complications / Q000276:immunology / Q000503:physiopathology*; D014655:Vascular Resistance
chemical_list: D001095:Arachidonic Acids