Occurrence of shared nonviral tumor-associated transplantation-type antigens among C3H/He mammary carcinomas.
The occurrence of shared nonviral tumor-associated antigens among 18 immunogenic C3H/He mammary carcinomas was investigated in vivo. By cross-immunization and s.c. challenge between pairs of tumors in 37 different combinations, six of the tumors were found to cross-immunize with one to three other tumors. A minimum of three different antigenic specificities were found to be shared among cross-reacting tumors.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis; D005260:Female; D006649:Histocompatibility Antigens / Q000032:analysis*; D008325:Mammary Neoplasms, Experimental / Q000276:immunology*; D051379:Mice; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation
D000951:Antigens, Neoplasm; D000939:Epitopes; D006649:Histocompatibility Antigens; C029237:tumor-associated transplantation antigen