title: Oral leukoplakias. A microradiographic and lipid-histochemical study.
abstract: Biopsies from 13 oral leukoplakias and from normal tissue specimens in the contralateral region of each patient were examined microradiographically and lipid-histochemically using freeze-sectioned and freeze-dried sections. The investigation showed that an epithelial zone of cell layers with different degrees of keratinization and varying dry mass concentrations occurred in oral leukoplakias. A concentrated localization of phospholipids, free fatty acids and cholesterols was found in the zones with a high dry mass content and, consequently, high keratin content, while a negative lipid reaction was obtained in the zones where the dry mass concentration was low.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005612:Freeze Drying; D006801:Humans; D007633:Keratins / Q000378:metabolism; D007972:Leukoplakia, Oral / Q000378:metabolism* / Q000473:pathology; D008055:Lipids / Q000032:analysis*; D008297:Male; D008852:Microradiography; D008875:Middle Aged
chemical_list: D008055:Lipids; D007633:Keratins