[Chemoprevention of carcinogenesis].
Inhibitors and their mechanisms of inhibition of various processes in chemical carcinogenesis, metabolic activation of chemical carcinogens followed by initiation and promotion in chemical carcinogenesis are reviewed. Furthermore, significance of the inhibitors of chemical carcinogenesis in foods and food additives and problems of side effects of these inhibitors are discussed.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology; D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D000242:Cyclic AMP / Q000494:pharmacology; D004273:DNA, Neoplasm / Q000378:metabolism; D005982:Glutathione Transferase / Q000494:pharmacology; D006801:Humans; D007372:Interferons / Q000494:pharmacology; D051379:Mice; D009369:Neoplasms / Q000473:pathology / Q000517:prevention & control* / Q000628:therapy; D009857:Oncogenes / Q000187:drug effects; D010634:Phenobarbital / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology; D051381:Rats; D012643:Selenium / Q000494:pharmacology; D014366:Tryptophan Oxygenase / Q000494:pharmacology; D014801:Vitamin A / Q000494:pharmacology
D004273:DNA, Neoplasm; D011480:Protease Inhibitors; D014801:Vitamin A; D015127:9,10-Dimethyl-1,2-benzanthracene; D007372:Interferons; D000242:Cyclic AMP; D014366:Tryptophan Oxygenase; D005982:Glutathione Transferase; D012643:Selenium; D010634:Phenobarbital