title: Pessimism concerning palliative bypass procedures for established malignant esophagorespiratory fistulas: a report of 18 patients.
abstract: Eighteen patients with established malignant esophagorespiratory fistulas due to primary esophageal cancer were managed by substernal gastric bypass and isolation of the cancerous esophageal segment. Seven fistulas were esophagotracheal and 11 were esophagobronchial. Ten patients died in the hospital between two days and six weeks after operation. Eight patients left the hospital, surviving an average of 3 1/2 months, but 2 patients lived 5 and 7 months, respectively. Unrelenting respiratory infection and clinical inanition caused 7 hospital deaths in patients reestablished on oral alimentation with their fistulas disconnected. Anastomotic leaks occurred in 5 patients; three of these leaks closed. In the other 2 patients, cervicomediastinal sepsis and bilateral pneumonia with respiratory failure caused death. One patient died of anoxic cardiac arrest 48 hours postoperatively. Fifteen of the 18 patients resumed oral alimentation, but the overall results of palliative surgical therapy achieved in this series were not observably worthwhile for the majority.
mesh_terms: D000328:Adult; D000368:Aged; D001983:Bronchial Fistula / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D004937:Esophageal Fistula / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000150:complications*; D004947:Esophagus / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D013270:Stomach / Q000601:surgery; D014138:Tracheoesophageal Fistula / Q000209:etiology / Q000401:mortality / Q000601:surgery*