title: [Cefotaxime concentration in the prostatic tissue].
abstract: Concentrations of cefotaxime (CTX) in serum and prostatic tissue were studied in human and rat. CTX kept high level of 40 to 100 micrograms/g in prostatic tissue at least as long as 2 hours following intraperitoneal injection in a dosis of 100 mg/kg of body weight in rat. Patients intravenously injected of 1 g of CTX showed the activity of 6.8 +/- 4.1 micrograms/g in prostatic tissue.
mesh_terms: D000368:Aged; D000818:Animals; D002439:Cefotaxime / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000378:metabolism*; D011470:Prostatic Hyperplasia / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002439:Cefotaxime