title: Immunological studies of human monoamine oxidases.
abstract: Antisera have been raised against monoamine oxidase preparations from human placenta and platelets. These antisera have been employed to characterize membrane-bound enzyme from a variety of human sources including liver, heart, and brain. The comparisons were based on a displacement radioimmunoassay system with soluble placental monoamine oxidase, previously labelled specifically with [3H]pargyline, as antigen. All forms of enzyme investigated demonstrated immunological cross reaction; however, the placental enzyme appeared to possess determinants not exhibited by the enzyme from the platelets or other tissues examined.
mesh_terms: D001792:Blood Platelets / Q000201:enzymology; D001921:Brain / Q000201:enzymology; D002462:Cell Membrane / Q000201:enzymology; D000939:Epitopes / Q000276:immunology; D005260:Female; D006801:Humans; D007163:Immunosorbent Techniques; D008099:Liver / Q000201:enzymology; D008995:Monoamine Oxidase / Q000276:immunology*; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy
chemical_list: D000939:Epitopes; D008995:Monoamine Oxidase