title: Fetal drug exposure-behavioral teratogenesis.
abstract: This paper reviews the neurobehavioral and developmental effects of fetal drug exposure. The drugs most commonly associated with adverse developmental outcome include alcohol, anticonvulsants (particularly phenytoin and trimethadione), narcotics, and some environmental toxins. Major limitations of studies examining the consequences of prenatal drug exposure on development include inadequate control of other confounding factors, uncertain accuracy of drug histories, and outcome criteria that provide insufficient delineation of subtle developmental delays.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects; D001519:Behavior / Q000187:drug effects*; D002186:Cannabinoids / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000139:chemically induced; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000523:psychology; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000523:psychology; D008607:Intellectual Disability / Q000139:chemically induced; D009294:Narcotics / Q000009:adverse effects; D011247:Pregnancy; D011581:Psychological Tests; D011619:Psychotropic Drugs / Q000009:adverse effects; D012907:Smoking; D013307:Streptomycin / Q000009:adverse effects; D013723:Teratogens; D013792:Thalidomide / Q000009:adverse effects
chemical_list: D000927:Anticonvulsants; D002186:Cannabinoids; D009294:Narcotics; D011619:Psychotropic Drugs; D013723:Teratogens; D013792:Thalidomide; D013307:Streptomycin