[Polyadenylated RNA and poly-A segments in the splenic cells of mice with virus-induced Rauscher leukemia].
In spleen cells of mice with Rauscher++ leukosis polyadenilation of RNA was impaired: an increase in content of Gya poly(A)+ RNA and a change in the composition of poly-A-segments were observed. In DNA of leukemic and normal cells dA-fragments were found content of which was increased in leukemic cells as compared with normal ones. Leukemic transformation appears to be accompanied by appearance of the additional poly-A-fragments in the cells.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D004279:DNA, Viral / Q000378:metabolism; D004587:Electrophoresis, Agar Gel; D007942:Leukemia, Experimental / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D011061:Poly A / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D012333:RNA, Messenger; D011925:Rauscher Virus; D013154:Spleen / Q000378:metabolism
D004279:DNA, Viral; D012333:RNA, Messenger; D011061:Poly A; D012313:RNA
Poliadenilirovannye RNK i poli-A-segmenty v kletkakh selezenki mysheĭ s virusindutsirovannym leĭkozom Raushera.