Immunological studies of patients with tumours of the prostate and bladder (a retrospective analysis).
A total of 25 patients with bladder tumour and 35 with prostatic tumour were tested for humoral and cellular immune responsiveness in 1977. Information on the subsequent course of disease was collected 5 years later and confronted with the results of these tests. The most marked deviations in the values of acute-phase proteins, complement and lymphocyte transformation tests were found in those patients who had died within the first year of the investigations. The results approached or attained the normal values parallel with the survival times. The parameters studied thus seem to lend themselves to diagnostic and monitoring purposes.
D000368:Aged; D000510:Alpha-Globulins / Q000032:analysis; D000917:Antibody Formation; D001609:Beta-Globulins / Q000032:analysis; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D010835:Phytohemagglutinins; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000276:immunology*; D012189:Retrospective Studies; D012712:Serum Globulins / Q000032:analysis*; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
D000510:Alpha-Globulins; D001609:Beta-Globulins; D007136:Immunoglobulins; D010835:Phytohemagglutinins; D012712:Serum Globulins