Effect of cold exposure on brain 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in some vertebrate species.
1. The changes in 5-HT and 5-HIAA levels were studied in the brain regions of Gerbillus pyramidum, Streptopelia senegalensis aegyptiaca and Agama stellio following exposure to cold. 2. In general, the 5-HT levels increased in the Gerbillus brain parts and decreased in those of Streptopelia. 3. Cold exposure in the Agama brain regions caused a transient decrease in the 5-HT levels of the cerebral hemispheres, midbrain and pons plus medulla after 6 hr and a general increase after 12, 24 and 48 hr. 4. It is concluded that cold exposure may be associated with increased activity of 5-HT ergic neurons and the rate of turnover of 5-HT to 5-HIAA.
D000818:Animals; D001717:Birds / Q000378:metabolism; D001833:Body Temperature Regulation; D001923:Brain Chemistry; D003080:Cold Temperature; D005260:Female; D005849:Gerbillinae / Q000378:metabolism; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism*; D008116:Lizards / Q000378:metabolism; D008297:Male; D012701:Serotonin / Q000378:metabolism*; D013045:Species Specificity
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid