title: [Comparison of the action of powerful pulses of ultrashort UV on the DNA replication and transcription functions in proliferating and resting HeLa cells].
abstract: It was established that the response of proliferating and resting HeLa cells to irradiation with single powerful UV-pulses (lambda = 266 nm, the pulse duration 3.10(-11) sec) is different. In the proliferating cells, the rate of DNA synthesis is markedly changed (accelerated or retarded) while the rate of RNA synthesis changes slightly. In the resting cells, RNA synthesis is stimulated while DNA synthesis remains at the control level. In all cases, the processes observed depend upon the intensity and the number of pulses.
mesh_terms: D002455:Cell Division / Q000528:radiation effects; D004247:DNA / Q000096:biosynthesis / Q000528:radiation effects; D004261:DNA Replication / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D006367:HeLa Cells / Q000528:radiation effects*; D006801:Humans; D007399:Interphase / Q000528:radiation effects; D007834:Lasers; D012313:RNA / Q000096:biosynthesis / Q000528:radiation effects; D014158:Transcription, Genetic / Q000528:radiation effects*; D014466:Ultraviolet Rays
chemical_list: D012313:RNA; D004247:DNA
vernacular_title: Sravnenie deĭstviia ul'trakorotkikh UF moshchnykh impul'sov na replikativnuiu i transkriptsionnuiu funktsiiu DNK v proliferiruiushchikh i pokoiashchikhsia kletkakh HeLa.