title: Immunohistochemical demonstration of plasma proteins in experimentally produced eosinophilic bodies ("keratin pools").
abstract: Different opinions exist about the nature of the material in eosinophilic bodies, or "keratin pools", in the epithelium of the human oral mucosa. The material has been described as keratin-like and as a filtrate from the blood vessels. In the rat forestomach eosinophilic bodies develop in the hyperplastic squamous epithelium following administration of a chemical carcinogen. In the present study this model is used for immunohistochemical studies of eosinophilic bodies. They are shown to contain fibrinogen and immunoglobulin and thus seem to develop as a result of pooling of plasma exudate in the epithelium.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis*; D004847:Epithelial Cells; D004848:Epithelium / Q000032:analysis; D005455:Fluorescent Antibody Technique; D005753:Gastric Mucosa / Q000032:analysis* / Q000166:cytology; D007633:Keratins / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001798:Blood Proteins; D007633:Keratins