Comparison of serum and urine hCG levels with SP1 and PAPP-A levels in patients with first-trimester vaginal bleeding.
Serum levels of human chorionic gonadotropin (hCG) in patients with threatened abortion are compared to the values in normal pregnancy. The predictive value was 93%, the sensitivity was 84%, and the prediction of gestational viability was 81% for the threatened group. These results compare favorably with urinary pregnancy testing and are similar to those obtained with the assay of Schwangerschaftsprotein I. Human chorionic gonadotropin was, however, a much better predictor of pregnancy outcome than pregnancy-associated plasma protein-A.
D000033:Abortion, Threatened / Q000097:blood* / Q000652:urine; D006063:Chorionic Gonadotropin / Q000032:analysis*; D005260:Female; D005328:Fetal Viability; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D011258:Pregnancy Tests; D011261:Pregnancy Trimester, First; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis*; D011336:Probability
D006063:Chorionic Gonadotropin; D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins; D011266:Pregnancy-Associated Plasma Protein-A