Transmitter sensitivities in oval neurons from rat brainstem cultures.
Using cultures of dissociated neurons from the lower brainstem of 14-15-day-old rat embryos, we studied a specific relation between neuronal activities of small-sized oval neurons and their sensitivities to various transmitter substances. Oval neurons were characterized by non-effective responses to acetylcholine and a facilitatory response to both leucine- and methionine-enkephalin.
D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D002478:Cells, Cultured; D004553:Electric Conductivity; D004622:Embryo, Mammalian; D004723:Endorphins / Q000494:pharmacology; D004745:Enkephalins / Q000494:pharmacology; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D051381:Rats; D013373:Substance P / Q000494:pharmacology; D001615:beta-Endorphin; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D004723:Endorphins; D004745:Enkephalins; D005971:Glutamates; D018377:Neurotransmitter Agents; D013373:Substance P; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D001615:beta-Endorphin