title: Acute retention of urine due to benign prostatic obstruction treated with alpha-adrenergic blockers.
abstract: Bladder catheterisation is the usual treatment in patients with acute retention of urine due to prostatic hypertrophy. The interference is not without complications why medical treatment would be a progress. The prostatic gland has been found to contain alpha-adrenergic receptors, and it has been argued that some cases of acute retention of urine is caused by over-stimulation of the alpha-adrenergic receptors. In the present study we have investigated the effect of intravenously administered phentolamine ( Regitin ) in patients with acute retention of urine, due to prostatic hypertrophy, and find that the treatment is an alternative to conventional bladder catheterisation.
mesh_terms: D000208:Acute Disease; D000368:Aged; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010646:Phentolamine / Q000008:administration & dosage / Q000627:therapeutic use*; D011470:Prostatic Hyperplasia / Q000150:complications*; D014555:Urination Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D010646:Phentolamine