title: Tachycardias initiated by automatic antitachycardia pacemakers.
abstract: Available automatic tachycardia-terminating pacemakers cannot distinguish between physiological and pathological tachycardia and, consequently, electrical stimulation during sinus tachycardia can occur. In order to evaluate whether this might be an arrhythmogenic problem or not, the cardiac response in eight patients having paroxysmal supraventricular tachycardia treated with tachycardia-terminating pacemakers was studied during exercise. After tachycardia recognition, the implanted pulse generator automatically emits single or double critically timed premature stimuli for termination of the arrhythmia. Post-implantation examinations revealed successful tachycardia termination by the pacemaker at rest, without the addition of any antiarrhythmic drugs, in all eight patients. During exercise tests, the sinus rate in seven patients exceeded the programmed tachycardia trigger rate resulting in triggered pacemaker stimulation. The native supraventricular tachycardia was initiated in four cases. In one of these patients, two short episodes of probable ventricular tachycardia were also recorded. This study demonstrates the clinical value of post-implantation assessments with exercise tests concerning the problem of pacemaker-initiated tachyarrhythmias. Tachycardia-terminating devices can induce tachycardias, and individual precautions must be taken in order to prevent or minimize the risk of pacemaker reversion of sinus rhythm to paroxysmal tachycardia or hazardous arrhythmias.
mesh_terms: D000328:Adult; D000368:Aged; D001283:Atrioventricular Node / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial / Q000379:methods; D004562:Electrocardiography; D004594:Electrophysiology; D005080:Exercise Test; D005260:Female; D006325:Heart Atria / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D012849:Sinoatrial Node / Q000503:physiopathology; D013610:Tachycardia / Q000209:etiology* / Q000628:therapy; D013614:Tachycardia, Paroxysmal / Q000209:etiology / Q000503:physiopathology