title: Slow negative evoked potentials in the rhesus monkey (Macaca mulatta): myogenic versus neurogenic influences.
abstract: The influence of myogenic activity on the generation of slow negative evoked potentials (SN10) to octave, toneburst stimuli (0.5-2 Hz) was investigated in 5 rhesus monkeys (M. mulatta) by comparing responses obtained prior to and during total paralysis induced with curare. The SN10 could be easily elicited during paralysis, regardless of stimulus intensity, rate, or frequency. During paralysis, there were no systematic changes in either response latency or amplitude; variability in latency was less than 10% and changes in response amplitude were within 30%. These findings suggest that the myogenic contribution to the SN10 response is negligible and that this response is of neurogenic origin in the rhesus monkey.
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D004576:Electromyography; D005071:Evoked Potentials; D008253:Macaca mulatta; D009132:Muscles / Q000502:physiology*; D010243:Paralysis / Q000503:physiopathology