title: Serum concentration of pregnancy-associated plasma protein A in the first trimester of pregnancy.
abstract: Serial assays of pregnancy-associated plasma protein A were done in 12 subjects before the first missed menstrual period through 10 to 16 weeks' gestation. It was found that the concentration of pregnancy-associated plasma protein A remained at prepregnancy levels until 6 to 10 weeks after the last menstrual period. Thereafter the concentration increased rapidly. It is surmised that pregnancy-associated plasma protein A is a maternal protein, the synthesis of which is stimulated by pregnancy.
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D011261:Pregnancy Trimester, First; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis*; D012044:Regression Analysis
chemical_list: D011257:Pregnancy Proteins; D011266:Pregnancy-Associated Plasma Protein-A