[Increase of the GvH reaction after alloimmunization. Influence of the serologically defined determinants of the H-2 system].
GvH reactions were induced in (CBA X C57B1)F1 and (CBA X A)F1 mice with sensitized lymphocytes. Specific sensitization results in an increased GvH reaction, sensitization against third party cells does not influence the GvH reaction. Therefore serologically defined public antigens of the H-2 system play not role in the GvH reaction. The comparison of different numbers of specifically sensitized lymphocytes, lymphocytes sensitized against third party cells, and control lymphocytes for the induction of the GvH reaction leads to the same result.
D000818:Animals; D003429:Cross Reactions; D000939:Epitopes / Q000276:immunology; D006087:Graft vs Host Reaction; D006183:H-2 Antigens / Q000276:immunology*; D007114:Immunization; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008805:Mice, Inbred A; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA
D000939:Epitopes; D006183:H-2 Antigens
Verstärkung der GvH-Reaktion durch Alloimmunisierung. Einfluss der serologisch determinierten Determinanten des H-2 Systems. Mit 1 Abbildung.