title: Genotypic, phenotypic, and biological characteristics of Moraxella bovis.
abstract: Several isolates of Moraxella bovis obtained from cattle with infectious bovine keratoconjunctivitis killed monocytes and macrophages in vitro and carried 3 to 5 plasmids. Cloned and noncloned M bovis isolates readily induced the disease, killed the phagocytes in vitro, and carried 3 plasmids. Moraxella bovis isolates of low in vivo virulence carried 5 plasmids and did not kill phagocytes to the extent that isolates with 3 plasmids did. The possible implications of these findings in the pathogenesis of infectious bovine keratoconjunctivitis are discussed. Also, a classification of M bovis colonies into rough or smooth varieties according to their staining characteristics with crystal violet is suggested.
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000382:microbiology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D003602:Cytotoxicity, Immunologic; D005838:Genotype; D005840:Gentian Violet; D006041:Goats / Q000276:immunology; D007637:Keratoconjunctivitis / Q000382:microbiology / Q000662:veterinary*; D008264:Macrophages / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D009016:Moraxella / Q000235:genetics* / Q000254:growth & development / Q000276:immunology / Q000472:pathogenicity; D010641:Phenotype; D010957:Plasmids; D013194:Staining and Labeling; D014774:Virulence
chemical_list: D005840:Gentian Violet