title: Management of high bile duct carcinoma.
abstract: Based on experience with six patients with high bile duct carcinoma, a rational therapeutic approach is proposed. When extent of tumor precludes resection, the authors recommend palliation with a biliary-enteric anastomsis to avoid the complications and inconveniences of long-term transhepatic stenting. This is best accomplished with construction of a left cholangiojejunostomy using the round ligament approach. Temporary bilobar decompression may be necessary in select cases.
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery* / Q000628:therapy; D002759:Adenoma, Bile Duct / Q000601:surgery* / Q000628:therapy; D000368:Aged; D001650:Bile Duct Neoplasms / Q000601:surgery* / Q000628:therapy; D001652:Bile Ducts / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008297:Male; D010166:Palliative Care
chemical_list: D005472:Fluorouracil