[In vitro aggregation of rat platelets by cumulative doses of ADP: influence of 3 antiaggregants and a protease inhibitor, aprotinin].
The authors describe the aggregation provoked on rat platelets using cumulative doses of ADP on the same sample. This model of aggregation is used to study the effects of three known aggregation inhibitors (aspirine, theophylline, isoproterenol) and one protease inhibitor, aprotinine.
D000244:Adenosine Diphosphate / Q000494:pharmacology*; D000818:Animals; D007611:Aprotinin / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013806:Theophylline / Q000494:pharmacology
D000244:Adenosine Diphosphate; D007611:Aprotinin; D013806:Theophylline; D007545:Isoproterenol; D001241:Aspirin
Agrégation in vitro des plaquettes de rat par doses cumulées d'ADP: influence de trois antiagrégants et d'un inhibiteur protéasique, l'aprotinine.