title: Pacemaker dependence in transient high-grade atrioventricular block.
abstract: In a prospective study 16 patients who had been given a pacemaker because of symptomatic high-grade atrioventricular block and whose conduction had been recovered were checked for their dependence on the pacemaker. During a follow-up time ranging from 32 to 158 months (median 62 months) six patients proved to be dependent on the device owing to the development of recurrent stable high-grade atrioventricular block. The subsequent return of atrioventricular block was evidently not associated with etiology, age, sex, ECG-pattern or length of follow-up period. Five additional patients equipped with a bradycardia-indicating pacemaker all proved to be pacemaker-dependent after a follow-up time ranging from 1-20 months (median 7 months), even though atrioventricular conduction had recovered and its presence had been confirmed at regular outpatient checks. It is thus evident that the conventional clinical methods are of limited value for examining the course of conduction defect and assessing the prognosis for patients whose spontaneous cardiac activity has returned after periods of symptomatic high-grade atrioventricular block. When a bradycardia-indicating pacemaker was furnished, pacemaker dependence was demonstrated in most of the patients whose atrioventricular conduction had recovered. This confirms that pacing introduced because of symptomatic high-grade atrioventricular block should not be discontinued even if a conducted heart rhythm has been established and maintained for long periods.
mesh_terms: D000368:Aged; D001919:Bradycardia / Q000209:etiology; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006327:Heart Block / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D011379:Prognosis; D011446:Prospective Studies