Heterogeneity among H-2Kk antigens. Differential expression on lymphoid cells.
Evidence is presented for heterogeneity in the expression of H-2Kk determinants specific for two monoclonal antibodies, H100-30.R3 and 11-4.1. Heterogeneity was detectable by differences in cellular distribution on thymocytes and activated T cells, but not by sequential immunoprecipitation or differential redistribution studies. This result contrasts with earlier evidence of heterogeneity, demonstrable by these latter methods, between H-2Kk determinants specific for H100-30.R3 and another antibody, H100-27.R9.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000939:Epitopes / Q000032:analysis*; D006183:H-2 Antigens / Q000276:immunology*; D008027:Light; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D012542:Scattering, Radiation; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
D000911:Antibodies, Monoclonal; D000939:Epitopes; D006183:H-2 Antigens; C024755:H-2K(K) antigen