[In vitro demonstration of the effect of lindane on isolated synaptosome preparations].
Lindane neurotoxicity is studied in vitro on Rat brain synaptosomes. Calcium uptake of isolated synaptosomes increases in the presence of pesticide; lindane action is observed on both normal and depolarized preparations.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D001921:Brain / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D001556:Hexachlorocyclohexane / Q000633:toxicity*; D066298:In Vitro Techniques; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013570:Synaptic Membranes / Q000502:physiology; D013574:Synaptosomes / Q000187:drug effects / Q000502:physiology*
D001556:Hexachlorocyclohexane; D002118:Calcium
Mise en évidence in vitro d'unme action du lindane sur des préparations de synaptosomes isolés.