The distribution of serotonin, met-enkephalin and beta-lipotropin-like immunoreactivity in neuronal perikarya of the cat brainstem.
The distribution of methionine-enkephalin, serotonin and beta-lipotropin-containing neurones has been mapped immunohistochemically in the brainstem of the cat after local colchicine injections. Serotonin-containing neurons were found in th raphe in nucleus raph magnus (NRM), nucleus raphe pallidus (NRP) and nucleus raphe obscurus (NRO) and in a band extending cross the ventral reticular formation into nucleus paragigantocellularis lateralis (PGL) and nucleus lateralis reticularis (LRM). Enkephalin-positive cell bodies were also found in these raphe nuclei and in most divisions of the caudal reticular formation. Double labelling studies established that enkephalin and serotonin co-exist within some neurons in NRM and NRP. beta-Lipotropin-positive cell bodies were found principally within NRP and within the ventrolateral reticular formation in PGL and LRM.
D000818:Animals; D001370:Axonal Transport; D001931:Brain Mapping; D002415:Cats; D004723:Endorphins / Q000378:metabolism*; D004744:Enkephalin, Methionine; D004745:Enkephalins / Q000378:metabolism*; D009434:Neural Pathways / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D011903:Raphe Nuclei / Q000378:metabolism; D012154:Reticular Formation / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism*; D008083:beta-Lipotropin / Q000378:metabolism*
D004723:Endorphins; D004745:Enkephalins; D012701:Serotonin; D004744:Enkephalin, Methionine; D008083:beta-Lipotropin