Epidemiology and control of staphylococcal pyoderma among newborn infants: evaluation of a method for routine cord care with 4 per cent chlorhexidine-detergent solution.
The incidence and types of staphylococcal purulent lesions were prospectively studied among 3602 newborn infants. During an epidemic of post-discharge pyoderma, 87 per cent of all Staphylococcus aureus isolates from lesions could be traced to the nursery. The risk of post-discharge disease was related to the degree of staphylococcal skin colonization in the nursery. A method for routine cord care in the nursery with 4 per cent chlorhexidine-detergent solution was evaluated and proved to be effective in reducing staphylococcal colonization in the nursery as well as purulent skin disease at home. The clinical effectiveness of the regimen was followed up for 19 months and a persistent low infection rate was obtained among infants in the post-discharge period.
D002710:Chlorhexidine / Q000627:therapeutic use*; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D003902:Detergents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007224:Infant Care / Q000379:methods; D007231:Infant, Newborn; D009725:Nurseries, Hospital; D011446:Prospective Studies; D011711:Pyoderma / Q000453:epidemiology / Q000517:prevention & control*; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000517:prevention & control*; D013548:Sweden; D014470:Umbilical Cord
D003902:Detergents; D002710:Chlorhexidine