[Electron microscopic and radioautographic study of nucleic acid synthesis in normal fatty tissue and lipomas].
Electron microscopic radioautography was used to study nucleic acid synthesis in the normal fatty tissue and lipomas of different degree of maturity. Destroyed adipocytes were found in the investigated varieties of the fatty tissue. In a slow-growing Madelung's lipoma such adipocytes occurred in a greater amount than in the normal fatty tissue and nongrowing lipomas. 3H-Thymidine was mainly incorporated by endotheliocytes and pericytes, whereas Madelung's lipoma contained a greater number of labeled cells. Based on the data obtained it is suggested that the replenishment of adipocytes occurs at the expense of the proliferation of vascular wall cells.
D000273:Adipose Tissue / Q000378:metabolism* / Q000648:ultrastructure; D000328:Adult; D001345:Autoradiography; D004247:DNA / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D005260:Female; D006258:Head and Neck Neoplasms / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D008067:Lipoma / Q000378:metabolism* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009694:Nucleic Acid Precursors / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis*; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D012016:Reference Values; D013936:Thymidine / Q000378:metabolism; D014529:Uridine / Q000378:metabolism
D004273:DNA, Neoplasm; D009694:Nucleic Acid Precursors; D012334:RNA, Neoplasm; D012313:RNA; D004247:DNA; D013936:Thymidine; D014529:Uridine
Elektronno-radioavtograficheskoe izuchenie sinteza nukleinovykh kislot v normal'noĭ zhirovoĭ tkani i lipomakh.