beta-thromboglobulin and platelet factor 4 levels in retinal vein occlusion.
Fifty-six patients with retinal vein occlusion--35 with central and 21 with branch vein occlusion--were investigated for comparison with an age and sex matched control group. Mean levels of beta-thromboglobulin and platelet factor 4 were significantly higher (p less than 0.001) in both the group with central and the group with branch retinal vein occlusion than in the control group. A significant increase of beta-thromboglobulin (p less than 0.001) was also found in the retinal vein occlusion group in those patients who were not hyperlipidaemic or diabetic (n = 39). Weak correlations were found between levels of lipoprotein cholesterol and plasma beta-thromboglobulin. Increased platelet aggregation may contribute to the aetiology of retinal vein occlusion.
D001609:Beta-Globulins / Q000032:analysis*; D001779:Blood Coagulation Factors / Q000032:analysis*; D003251:Constriction, Pathologic; D003930:Diabetic Retinopathy; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D010978:Platelet Factor 4 / Q000032:analysis*; D012164:Retinal Diseases / Q000097:blood / Q000209:etiology; D012169:Retinal Vein; D001620:beta-Thromboglobulin / Q000032:analysis*
D001609:Beta-Globulins; D001779:Blood Coagulation Factors; D008074:Lipoproteins; D001620:beta-Thromboglobulin; D010978:Platelet Factor 4