[Effect of fenfluramine in Huntington Chorea].
Serotoninergic function has been evaluated in 15 H.C. patients. Therapeutic results obtained with an inhibitor of 5 HT reuptake (Fenfluramine) were evaluated in comparison to the effects of L-5HTP, CSF-5HIAA measurements were performed is each case before and after treatment. The pathological role of 5HT impairment in H. C. can not be excluded by the behavioral effects and CSF-5HIAA modifications that were observed.
D006916:5-Hydroxytryptophan / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D005277:Fenfluramine / Q000134:cerebrospinal fluid / Q000627:therapeutic use*; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D006816:Huntington Disease / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000134:cerebrospinal fluid; D008875:Middle Aged
D005277:Fenfluramine; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D006916:5-Hydroxytryptophan; D006719:Homovanillic Acid
Effet de la fenfluramine dans la chorée de Huntington.