[Effect of antisynaptosome antibodies on the metabolism of synaptosomal proteins].
The authors studied the effect of intraventricular injection of antisynaptosomal gamma-globulin on the protein of synaptosomal proteins in the rat brain cortex. The effect was assesed according to the protein specific radioactivity 2 and 3 hours after injection into animals of 14C-protein hydrolysate of Chlorella. Injection of antisynaptosomal gamma-globulin provoked an increase and reduction in the specific radioactivity of the proteins under study 2 and 3 hours, respectively, after labeled precursor injection. It is assumed that interaction of synaptosomal antibodies with protein synaptosomal antigens produces intense decay of antigens, leading to activation of their synthesis.
D000818:Animals; D000906:Antibodies / Q000502:physiology*; D002540:Cerebral Cortex / Q000276:immunology; D002708:Chlorella; D007114:Immunization; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D013574:Synaptosomes / Q000276:immunology* / Q000378:metabolism; D013997:Time Factors; D005719:gamma-Globulins / Q000276:immunology
D000906:Antibodies; D009419:Nerve Tissue Proteins; D005719:gamma-Globulins
Izuchenie vliianiia antisinaptosomal'nykh antitel na obmen sinaptosomal'nykh belkov.