The effect of experimental glaucoma on vitreous volume.
Long-term unilateral blocking of the trabecular meshwork with Dextran blue 2000, in 10 rabbits, produced intraocular pressure rise and a significant gain in vitreous mass. These experimental findings were in variance with the previous clinical observation of definitely reduced vitreous volume in phacolytic glaucomatous patients. The reason for this discrepancy is discussed.
D000818:Animals; D004396:Coloring Agents / Q000494:pharmacology; D003911:Dextrans / Q000494:pharmacology; D005901:Glaucoma / Q000473:pathology*; D007429:Intraocular Pressure / Q000187:drug effects; D007700:Kinetics; D009929:Organ Size / Q000187:drug effects; D011817:Rabbits; D014129:Trabecular Meshwork / Q000187:drug effects; D014822:Vitreous Body / Q000187:drug effects / Q000473:pathology*
D004396:Coloring Agents; D003911:Dextrans; C017080:blue dextran