[Allergic reactions to patent blue violet: mechanisms, frequency and treatment].
The authors report their observation of a serious allergic incident involving the blue patent, hospitalisation in their intensive care unit, and extremely major therapy. They describe the three mechanisms of allergic reaction: real anaphylaxia, and anaphylactoid reaction, either by direct histamino-release, or by alternate activation of the complementary system. It would seem that, after doses of the differing fractions of complement in this patient, there was an activation of the complementary system. The authors emphasize the importance of preventive treatment: hypo-histamine, antihistamine, corticoid, and curative relative to the gravity of the disorders observed: cutaneous, cardiac, and respiratory. Finally, they recall that this test must be carried out in a hospital establishment with a reanimation unit.
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000937:Antigen-Antibody Reactions; D001986:Bronchial Spasm / Q000139:chemically induced / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006636:Histamine Release; D006801:Humans; D008220:Lymphography; D011292:Premedication; D012394:Rosaniline Dyes / Q000009:adverse effects*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D006634:Histamine H1 Antagonists; D012394:Rosaniline Dyes; D014662:Vasoconstrictor Agents; C008769:sulfan blue; D004837:Epinephrine
Les accidents allergiques au blue patent violet. Mécanismes, fréquence et traitement.