[Inhibition of an immune hemolysis reaction in higher vertebrates by a serum fraction (fraction P) from the pregnant Salamandra salamandra L].
Serum "fraction P" from Salamandra pregnant female (containing essentially an alpha 2-macroglobulin) possesses non specific cellular immunosuppressive properties [2]. This fraction has been tested in an immune hemolysis reaction: hemolytic Rabbit IgG + guinea-pig complement + Sheep erythrocytes. This fraction, after incubation with guinea-pig complement, inhibits immune lysis.
D000818:Animals; D001769:Blood; D003165:Complement System Proteins / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006461:Hemolysis; D007074:Immunoglobulin G; D007165:Immunosuppression Therapy; D008297:Male; D011247:Pregnancy; D011817:Rabbits; D012454:Salamandra / Q000276:immunology*; D012756:Sheep; D000511:alpha-Macroglobulins / Q000276:immunology*
D007074:Immunoglobulin G; D000511:alpha-Macroglobulins; D003165:Complement System Proteins
Inhibition d'une réaction d'hémolyse immune chez les vertébrés supérieurs par une fraction sérique (fraction P) de femelle gestante chez Salamandra salamandra L.