[Dynamics of initial L-cell adhesion. II. Competition of albumin and serum activating factor].
The initial attachment process of L cells is studied by the combined action of serum and albumin. Both the substances are added jointly in the Eagle medium or one of them was adsorbed on the substrate previously. The results show that there are two factors in the serum: one depressing the cell attachment, like albumin, and the other being just opposite. The simple kinetical competition model is suggested to describe the experimental dependence of final level of attachment on the concentrations of serum and albumin. The examination of the thermal resistance of the serum factor is made; the previous heating to 60-100 degrees C increases the depressing effect of serum and albumin.
D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D001798:Blood Proteins / Q000494:pharmacology*; D002417:Cattle; D002448:Cell Adhesion / Q000187:drug effects; D006023:Glycoproteins / Q000494:pharmacology*; D006801:Humans; D007700:Kinetics; D007739:L Cells / Q000187:drug effects* / Q000502:physiology; D008297:Male; D051379:Mice; D012709:Serum Albumin / Q000494:pharmacology*; D012710:Serum Albumin, Bovine / Q000494:pharmacology*; D013696:Temperature; D019096:Vitronectin
D001798:Blood Proteins; D006023:Glycoproteins; D012709:Serum Albumin; D019096:Vitronectin; D012710:Serum Albumin, Bovine
Dinamika nachal'nogo prikrepleniia L'kletok. II. Konkurentsiia al'bumina i aktiviruiushchego faktora syvorotki.