title: [Antitubercular agents].
abstract: Author resume the most important stages of the antitubercular struggle. Then they consider the action mechanisms of single drugs, often not well known, such the action mechanism of pyrazinamide. At present, the criteria of effectiveness, tolerance, availability and economy allow to use rationally and not arbitrarily the antitubercular drugs and these criteria also assure the best therapeutic results.
mesh_terms: D000963:Antimetabolites / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use / Q000633:toxicity; D004247:DNA / Q000037:antagonists & inhibitors; D004977:Ethambutol / Q000627:therapeutic use; D005000:Ethionamide / Q000627:therapeutic use; D005493:Folic Acid Antagonists / Q000627:therapeutic use; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D012313:RNA / Q000037:antagonists & inhibitors; D012293:Rifampin / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000963:Antimetabolites; D000995:Antitubercular Agents; D005493:Folic Acid Antagonists; D012313:RNA; D004977:Ethambutol; D004247:DNA; D005000:Ethionamide; D007538:Isoniazid; D012293:Rifampin
vernacular_title: I farmaci antitubercolari.