[Detection of common determinants of HLA antigens A2 and B17 by absorption using human HLA serum].
Attempts of cross absorption where sera of anti-HLA A2 + B17, anti-HLA A2 and anti-HLA B17 with thrombocytes were absorbed from donors of HLA A2 positive, B17 negative and HLA A2 negative, B17 positive, revealed that anti-HLA A2 and anti-HLA B17 could be eliminated from the sera of both HLA types on the platelets. Thus, the findings allow the existence of a common determinant of HLA A2 and B17-antigens to be assumed. This is the first case where the evidence of a cross reaction between antigens of two different HLA loci with human sera could be established.
D000042:Absorption; D001792:Blood Platelets / Q000276:immunology; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis*; D006680:HLA Antigens / Q000032:analysis / Q000378:metabolism*; D006801:Humans
D000939:Epitopes; D006680:HLA Antigens
Nachweis einer gemeinsamen Determinante der HLA-Antigene A2 und B17 durch Absorption mit menschlichen HLA-Seren.