title: [Early histochemical markers of hepatocarcinogenesis].
abstract: Results of hepatocarcinogenesis studies are reviewed. The studies were made using different histochemical markers which permit revealing hyperplastic nodules in the liver. Determination of the gamma-glutamyl transpeptidase, ATPase, glucose-6-phosphatase activities and the glycogen, iron, alpha-fetoprotein contents are advisable when studying early changes in different cell populations during hepatocarcinogenesis.
mesh_terms: D015073:2-Acetylaminofluorene; D000251:Adenosine Triphosphatases / Q000172:deficiency; D000818:Animals; D004052:Diethylnitrosamine; D005953:Glycogen Storage Disease Type I / Q000139:chemically induced / Q000378:metabolism; D006651:Histocytochemistry; D006965:Hyperplasia; D000090463:Iron Deficiencies; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008112:Liver Glycogen / Q000378:metabolism; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D011230:Precancerous Conditions / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D051381:Rats; D013997:Time Factors; D000509:alpha-Fetoproteins / Q000032:analysis; D005723:gamma-Glutamyltransferase / Q000172:deficiency
chemical_list: D008112:Liver Glycogen; D000509:alpha-Fetoproteins; D004052:Diethylnitrosamine; D015073:2-Acetylaminofluorene; D005723:gamma-Glutamyltransferase; D000251:Adenosine Triphosphatases
vernacular_title: Rannie gistokhimicheskie markery gepatokantserogeneza.