[Inhibition of the accumulation of the Lassa virus in Vero cells by immune gamma globulin and complement].
Specific inhibition of Lassa virus replication in Vero cells was found to be better achieved with immune gamma globulin in combination with complement than with gamma globulin alone. According to the authors, the inhibitory effect of these preparations is due to the cyto-destructive action of antibodies and complement on the infected cells.
D000818:Animals; D001116:Arenaviridae / Q000276:immunology*; D002460:Cell Line; D003165:Complement System Proteins / Q000276:immunology*; D003588:Cytopathogenic Effect, Viral; D003602:Cytotoxicity, Immunologic; D004306:Dose-Response Relationship, Immunologic; D007108:Immune Tolerance; D007836:Lassa virus / Q000276:immunology* / Q000472:pathogenicity; D014776:Virus Cultivation; D005719:gamma-Globulins / Q000276:immunology*
D005719:gamma-Globulins; D003165:Complement System Proteins
Podavlenie nakopleniia virusa Lassa v kletkakh Vero immunnym gamma-globulinom i komplementom.