A private strain-specific idiotype-like structure discovered on CBA-anti-C57BL/6 T lymphocytes.
Using rabbit anti-CBA-anti-C57BL/6 sera, a private strain-specific idiotype-like determinant(s) was detected by cellular radioimmunoassay on activated CBA-anti-C57BL/6 T cells. This structure was not expressed on other activated T lymphocytes: CBA-anti-BALB/c; C3H-anti-C57BL/6; AKR-anti-C57BL/6; A/Sn-anti-C57BL/6; BALB/c- anti-C57BL/6; DBA/2-anti-C57BL/6. It is suggested that the gene(s) coding for the private strain-specific idiotype-like determinant(s) of T-cell antigen-recognizing receptors is not located within the murine H-2 complex.
D000818:Animals; D000939:Epitopes / Q000235:genetics; D007130:Immunoglobulin Idiotypes / Q000235:genetics*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D011817:Rabbits; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
D000939:Epitopes; D007130:Immunoglobulin Idiotypes