Thermal trauma-induced changes in the synthesis of rat serum proteins.
Infliction of non-lethal scalding was found to cause an increase in the rate of incorporation of 35S-methionine into albumin and globulin fractions of rat serum proteins, the the increase being remarkably higher for alpha- and beta-globulins than for albumin and gamma-globulins The most pronounced enhancement was associated with the 60- and 70-kd constituents of beta-globulins, the 34-, 55- and 136-kd polypeptides of alpha-2-globulins and the 50-, 60-, 125- and 145-kd polypeptides of alpha-1-globulins. The response of serum proteins to the heat shock was similar, though the changes were significantly less pronounced.
D000510:Alpha-Globulins / Q000096:biosynthesis; D000818:Animals; D001609:Beta-Globulins / Q000096:biosynthesis; D001798:Blood Proteins / Q000096:biosynthesis*; D004586:Electrophoresis; D006358:Hot Temperature; D008297:Male; D008715:Methionine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012709:Serum Albumin / Q000096:biosynthesis / Q000378:metabolism; D005719:gamma-Globulins / Q000096:biosynthesis
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D012709:Serum Albumin; D005719:gamma-Globulins; D008715:Methionine