[Granulomatous hepatic localizations in Whipple's disease. Apropos of 2 cases].
In two patients "granulomatous hepatitis" was diagnosed upon examination of liver biopsy specimens taken because of prolonged fever with poor general condition. Observed lesions were small nodules without necrosis: follicular adentitis was also found in one patient. Diagnosis of Whipple disease was established by examination of a biopsy specimen of the intestinal mucosa. Study of the hepatic lesions after Gram and PAS staining, done in one patient, did not demonstrate the suggestive intrahistiocytic particles. Confrontation of clinical evidence and histologic findings in lymph node and intestinal biopsy specimens is required for diagnosis.
D000328:Adult; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006505:Hepatitis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008297:Male; D008061:Whipple Disease / Q000150:complications / Q000473:pathology
Localisations granulomateuses hépatiques au cours de la maladie de Whipple. A propos de deux observations.