The influence of age on the induction of delayed hypersensitivity to human gamma globulin.
Delayed hypersensitivity (DH) reactions by chickens to human gamma globulin (HGG) were influenced by age. Chickens 6 to 12 weeks of age exhibited a significantly greater DH reaction than 3-week-old chickens. The injection of HGG 1, 2, or 3 weeks after sensitization did not significantly influence the DH reactions. Our data allow us to reject the hypothesis that there is no significant age difference in the DH response of chickens.
D000367:Age Factors; D000818:Animals; D002645:Chickens / Q000276:immunology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000662:veterinary*; D011201:Poultry Diseases / Q000276:immunology*; D005719:gamma-Globulins / Q000276:immunology*
D005719:gamma-Globulins