title: Immunogenicity of fatty acid anilides in rabbits and the pathogenesis of the Spanish toxic oil syndrome.
abstract: Fatty acid anilides, the major xenobiotic found in the cooking oils responsible for the Spanish toxic oil syndrome, are immunogenic for rabbits as ascertained by a skin test reaction, the characterization of specific antibodies against anilides and the immunofluorescent detection of 'anilide dependent antigens' in tissue slices from treated animals.
mesh_terms: D000813:Anilides / Q000276:immunology* / Q000633:toxicity; D000818:Animals; D000906:Antibodies / Q000032:analysis; D001921:Brain / Q000276:immunology; D001937:Brassica; D004342:Drug Hypersensitivity / Q000209:etiology*; D000939:Epitopes / Q000032:analysis; D005229:Fatty Acids, Monounsaturated; D005455:Fluorescent Antibody Technique; D005506:Food Contamination; D007114:Immunization; D007163:Immunosorbent Techniques; D008041:Linoleic Acids / Q000276:immunology* / Q000633:toxicity; D008081:Liposomes / Q000008:administration & dosage; D009132:Muscles / Q000276:immunology; D009468:Neuromuscular Diseases / Q000209:etiology*; D009821:Oils / Q000506:poisoning*; D009829:Oleic Acids / Q000276:immunology* / Q000633:toxicity; D010938:Plant Oils; D011817:Rabbits; D000074262:Rapeseed Oil; D012882:Skin Tests; D013577:Syndrome
chemical_list: D000813:Anilides; D000906:Antibodies; D000939:Epitopes; D005229:Fatty Acids, Monounsaturated; D008041:Linoleic Acids; D008081:Liposomes; D009821:Oils; D009829:Oleic Acids; D010938:Plant Oils; D000074262:Rapeseed Oil; C039294:linoleylanilide; C038731:oleoylanilide