title: Fibrin seal application. Clinical experience.
abstract: Clinical experience with fibrin gluing in cardiovascular surgery now extends over 4 years. The adhesive has been employed prophylactically for preclotting of prostheses or sealing of various suture lines including those of the bronchial system of infants. Together with collagen fleece it has turned out to be most effective for control of superficial bleeding due to adhesions or sources of bleeding difficult to reach. Two clinical examples are presented demonstrating the life-saving application of the collagen patch and fibrin gluing method.
mesh_terms: D000328:Adult; D001011:Aorta / Q000601:surgery; D001018:Aortic Diseases / Q000628:therapy; D001980:Bronchi / Q000601:surgery; D013504:Cardiovascular Surgical Procedures; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D005260:Female; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D006350:Heart Valve Prosthesis; D006470:Hemorrhage / Q000209:etiology / Q000628:therapy; D006489:Hemostatic Techniques; D006801:Humans; D007223:Infant; D008875:Middle Aged; D008943:Mitral Valve; D011183:Postoperative Complications / Q000628:therapy; D013917:Thrombin / Q000627:therapeutic use*; D000267:Tissue Adhesions / Q000150:complications; D014014:Tissue Adhesives; D014132:Trachea / Q000601:surgery
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin