title: [Characteristics of erythrocyte acid and osmotic resistance in thyrotoxicosis before and after treatment].
abstract: An increased acid resistance of peripheral erythrocytes was revealed in 62 thyrotoxic patients, examined in clinics. The most pronounced erythrocyte acid resistance was seen in patients with the disease of a moderate degree. Erythrocyte osmotic resistance was enhanced in patients with the mild and/or moderate stages of the disease and lowered in severe thyrotoxicosis. After antithyroid therapy erythrocyte acid resistance diminished in patients with the mild and moderate forms and elevated in severe thyrotoxicosis. Erythrocyte osmotic resistance returned to normal in the treatment of severe thyrotoxic patients, remaining enhanced in the moderate stage of the disease. The data obtained may be used to determine thyrotoxicosis severity, effectiveness of antithyroid therapy and mechanisms, affecting the peripheral blood erythrocyte properties.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D013956:Antithyroid Agents / Q000008:administration & dosage; D002908:Chronic Disease; D004912:Erythrocytes / Q000502:physiology*; D004920:Erythropoiesis; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009996:Osmotic Fragility; D013960:Thyroid Function Tests
chemical_list: D013956:Antithyroid Agents
vernacular_title: Osobennosti kislotnoĭ i osmoticheskoĭ rezistentnosti éritrotsitov u bol'nykh tireotoksikozom do i posle lecheniia.