New dextran derivatives. II. Preparation of compounds of copper (II) with 3-mercapto-2-hydroxypropyl ether of dextran.
The non-ionic compound of 3-mercapto-2-hydroxypropyl ether of dextran with cupric sulphide was obtained. The compound (called C-79) exhibited biological activity at parenteral administration to laboratory animals. The method of obtaining the compound as well as the properties of the latter were described. The results of gel chromatography suggested the existence of certain analogies with the known compounds of iron with dextran.
D000818:Animals; D003300:Copper / Q000494:pharmacology / Q000633:toxicity; D003911:Dextrans / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D007928:Lethal Dose 50; D051379:Mice
D003911:Dextrans; C018905:dextran-2-hydroxy-3-mercaptopropyl ether; D003300:Copper