Two interchangeable forms of ciguatoxin.
Ciguatoxin, the principal toxin responsible for ciguatera, isolated from moray eel viscera, has been separated into two distinct components by alumina chromatography. A series of chromatographies showed that the two components are interchangeable. This proves that ciguatoxin is a single molecular entity. Both forms were crystallized and their 1H NMR spectra were recorded.
D000537:Aluminum Oxide; D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002845:Chromatography / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002922:Ciguatoxins / Q000032:analysis* / Q000633:toxicity; D003460:Crystallization; D003911:Dextrans; D004524:Eels; D005260:Female; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D008387:Marine Toxins / Q000032:analysis*; D051379:Mice; D012824:Silicic Acid; D013997:Time Factors
D003911:Dextrans; D008387:Marine Toxins; D002922:Ciguatoxins; D012824:Silicic Acid; C025614:sephadex; D000537:Aluminum Oxide