Biochemical analysis of rat testis and epididymis after cyproterone acetate treatment.
Male rats were treated with cyproterone acetate (10 mg/day/rat) for 13, 26 and 39 days. A marked decrease in proteins, nucleic acid and phospholipid content was recorded in testis and epididymis after CA treatment. However, a significant increase in glycogen and cholesterol content in testis and epididymis was observed after CA treatment.
D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D003534:Cyproterone / Q000031:analogs & derivatives* / Q000494:pharmacology; D017373:Cyproterone Acetate; D004247:DNA / Q000378:metabolism; D004822:Epididymis / Q000187:drug effects*; D006003:Glycogen / Q000378:metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D051381:Rats; D011944:Receptors, Androgen / Q000187:drug effects; D013737:Testis / Q000187:drug effects*
D010743:Phospholipids; D011506:Proteins; D011944:Receptors, Androgen; D017373:Cyproterone Acetate; D012313:RNA; D006003:Glycogen; D004247:DNA; D002784:Cholesterol; D003534:Cyproterone