title: DNA methylation in chicken brain and liver.
abstract: Adult chicken brain DNA is subject to a developmental alteration of methylation at HpaII sites flanking 4, 1, 0.8 and 0.7 kilobase sequences. This change is not evident in adult chicken liver DNA and 1-day-old chick brain and liver DNAs, suggesting tissue specificity and age-dependency in DNA methylation.
mesh_terms: D000375:Aging; D000818:Animals; D001483:Base Sequence; D001921:Brain / Q000378:metabolism*; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000378:metabolism*; D004262:DNA Restriction Enzymes; D019003:Deoxyribonuclease HpaII; D005260:Female; D008099:Liver / Q000378:metabolism*; D008745:Methylation; D014018:Tissue Distribution
chemical_list: D004247:DNA; D004262:DNA Restriction Enzymes; D019003:Deoxyribonuclease HpaII