EMG activity of pigeon oesophagus in vivo.
At rest, the pigeon cervical oesophagus, which is entirely smooth muscle, shows electric activity. This activity consists of bursts of spikes with frequency increasing in the oral-aboral direction. The bursts are un-phase locked, and there are no slow waves (E.C.A.). The surgical transection of the oesophageal muscular wall does not affect the electric activity even in a disconnected segment. After asphyxia electric activity persists, whereas the aboral gradient of frequency disappears. Therefore, the electric activity is thought to be myogenic in origin, and the frequency gradient nervous in origin. Atropine and neostigmine administration suggests that the cholinergic system modulates the electric activity, but it is not involved in the control of the frequency gradient. On the contrary, hexamethonium administration, by abolishing this gradient, lends support to the idea of a postganglionic atropine-resistant neuronal system responsible for the gradient.
D000200:Action Potentials; D000818:Animals; D001237:Asphyxia / Q000503:physiopathology; D001285:Atropine / Q000494:pharmacology; D010856:Columbidae; D004576:Electromyography; D004594:Electrophysiology; D004947:Esophagus / Q000187:drug effects / Q000502:physiology*; D006584:Hexamethonium Compounds / Q000494:pharmacology; D009388:Neostigmine / Q000494:pharmacology
D006584:Hexamethonium Compounds; D009388:Neostigmine; D001285:Atropine