Familial minor neurodevelopmental disorders.
Sixteen patients (13 males and 3 females) with minor neurodevelopmental disorders from 7 families were examined in an etiologic study. In four of the families (3, 5, 6 and 7) no brain damaging factors could be traced in the prenatal, perinatal or postnatal periods, and genetic main etiologies were strongly suspected. In one family (1) alcohol abuse during the pregnancies was thought to be an etiologically contributing factor. Potentially brain damaging factors were demonstrated in at least one patient from each of the remaining two families (2 and 4), and might, in these cases, have interacted with hereditary factors.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology / Q000235:genetics*; D005260:Female; D006801:Humans; D007859:Learning Disabilities / Q000209:etiology / Q000235:genetics*; D008297:Male; D001523:Mental Disorders / Q000209:etiology / Q000235:genetics; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology / Q000235:genetics*; D009460:Neurologic Examination; D010375:Pedigree