The effects of acidic epididymal glycoprotein (AEG) and some other proteins on the motility of rat epididymal spermatozoa.
Acidic epididymal glycoprotein (AEG) had a slight stimulatory effect on the motility of spermatozoa showing low initial motility which had been removed by micropuncture from the caput and corpus epididymidis of rats. However, similar effects were seen when bovine serum albumin (BSA) or purified gammaglobulin against AEG was used instead of AEG. Furthermore, BSA, normal rabbit serum and serum from a rabbit immunized against AEG reduced the motility of spermatozoa which showed high initial motility after removal from the caput, while AEG had no effect. These studies emphasize the importance of the effects of proteins on the motility of spermatozoa but do not provide any clear evidence for a specific effect of AEG.
D000818:Animals; D004822:Epididymis; D006023:Glycoproteins / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D013081:Sperm Motility / Q000187:drug effects*; D013997:Time Factors; D005719:gamma-Globulins / Q000494:pharmacology
D006023:Glycoproteins; D005719:gamma-Globulins; D012710:Serum Albumin, Bovine