Naturally occurring T lymphocytotoxic antibody in viral and related skin diseases.
The naturally occurring T lymphocytotoxic antibodies in patients with viral and related skin diseases were investigated and compared with those of systemic lupus erythematosus (SLE). The incidences of T lymphocytotoxic antibodies in exanthema suspected of viral infection, infectious mononucleosis, rubella and pityriasis rosea were 28%, 44%, 8% and 28% respectively. Sera from patients with herpes zoster and erythema infectiosum did not show positivity. Incidence in SLE sera as positive control was 82%. The T lymphocytotoxic antibodies detected in skin diseases were similar in nature to those of SLE patients, but were transient and lower in titer than those of SLE.
D000914:Antibodies, Viral / Q000276:immunology*; D004890:Erythema / Q000276:immunology; D005076:Exanthema / Q000276:immunology; D006562:Herpes Zoster / Q000276:immunology; D006801:Humans; D007244:Infectious Mononucleosis / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D008623:Mercaptoethanol / Q000494:pharmacology; D010915:Pityriasis / Q000276:immunology; D012397:Rosette Formation; D012409:Rubella / Q000276:immunology; D012871:Skin Diseases / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000187:drug effects / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*
D000914:Antibodies, Viral; D008623:Mercaptoethanol