Orthograde and retrograde axonal movement of label and transneuronal transport phenomena after intraocular injection of [3H]adenosine in a poikolotherm vertebrate (Vipera aspis).
The axoplasmic transport of [3H]adenosine (or its related compounds) has been examined radioautographically in the visual system of a poïkilotherm species (Vipera aspis) following an intraocular injection of the nucleoside. It has been found that the axonal transport of the label occurs both in the anterograde directions. Furthermore, a considerable labelling of neuronal bodies as a result of transneuronal transport of tritiated material from the optic endings has been observed, particularly in the primary optic centers. Transneuronal labelling, however, appears less intense than retrograde cell labelling.
D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D001370:Axonal Transport; D001931:Brain Mapping; D012911:Snakes / Q000033:anatomy & histology / Q000378:metabolism*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000378:metabolism*
D000241:Adenosine