title: Von Willebrand's disease. Clinical picture, diagnosis, and treatment.
abstract: Recent developments regarding von Willebrand's disease, a complex disorder of hemostasis, have been helpful in understanding the clinical and laboratory manifestations of the disorder. This article discusses the pathogenesis and classification of the disorder, the role of von Willebrand factor in hemostasis, genetic counseling, and approaches to treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications; D001792:Blood Platelets / Q000502:physiology; D001803:Blood Transfusion; D001808:Blood Vessels / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D000939:Epitopes; D004967:Estrogens / Q000627:therapeutic use; D005169:Factor VIII / Q000502:physiology / Q000627:therapeutic use; D005817:Genetic Counseling; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000150:complications; D012310:Ristocetin / Q000494:pharmacology; D014842:von Willebrand Diseases / Q000145:classification / Q000235:genetics / Q000628:therapy; D014841:von Willebrand Factor / Q000502:physiology
chemical_list: D000939:Epitopes; D004967:Estrogens; D014841:von Willebrand Factor; D012310:Ristocetin; D005169:Factor VIII