Evaluation of toxicity of intravitreal antineoplastic drugs.
We evaluated the toxic and nontoxic doses of eight antineoplastic drugs in the vitreous cavity of rabbits. These drugs may have implications in the prevention of cell proliferation in the vitreous.
D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D001761:Bleomycin / Q000633:toxicity; D002945:Cisplatin / Q000633:toxicity; D003561:Cytarabine / Q000633:toxicity; D003609:Dactinomycin / Q000633:toxicity; D004317:Doxorubicin / Q000633:toxicity; D005047:Etoposide / Q000633:toxicity; D007267:Injections; D008937:Mitomycins / Q000633:toxicity; D011817:Rabbits; D012160:Retina / Q000473:pathology; D014750:Vincristine / Q000633:toxicity; D014822:Vitreous Body
D000970:Antineoplastic Agents; D008937:Mitomycins; D003561:Cytarabine; D001761:Bleomycin; D003609:Dactinomycin; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D002945:Cisplatin