Interaction of nucleic acids with the DNA-dependent RNA polymerases of Drosophila.
The interaction between the three Drosophila DNA-dependent RNA polymerases (EC 2.7.7.6) and the DNA template or the RNA product was investigated by photochemical cross-linking and binding studies, using RNA polymerase subunits immobilized on nitro-cellulose filters. It can be shown that the two largest subunits are responsible for the binding of the enzymes to both template and newly-synthesized RNA.
D000818:Animals; D004247:DNA / Q000378:metabolism* / Q000528:radiation effects; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism* / Q000528:radiation effects; D004330:Drosophila; D010777:Photochemistry; D011485:Protein Binding / Q000528:radiation effects; D012313:RNA / Q000378:metabolism* / Q000528:radiation effects
D012313:RNA; D004247:DNA; D012321:DNA-Directed RNA Polymerases