Unusual metastatic patterns of prostate adenocarcinoma.
While prostatic adenocarcinoma is associated classically with osseous or lymphatic metastasis, it can present clinically with protean manifestations. We describe 4 cases that demonstrate unusual patterns of metastatic spread, including isolated supraclavicular mass, pleural effusion, suprapubic and genital skin metastasis, and priapism. Newer immunohistochemical staining techniques for prostate specific antigen and prostatic acid phosphatase can assist in localization of the metastatic adenocarcinoma to a prostatic origin.
D000135:Acid Phosphatase / Q000032:analysis; D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D002968:Clavicle; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion; D011317:Priapism / Q000209:etiology; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000556:secondary*
D000951:Antigens, Neoplasm; D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen