Characterization of radioactive human fibroblast-derived beta interferon synthesized in vivo.
Radioactive human fibroblast-derived beta interferon has been synthesized in vivo after induction of human diploid fibroblast cells with poly I:C. The radioactive protein is not synthesized and secreted by uninduced cells. It reacts with antibody made against homogeneous human beta interferon and has the same N-terminal amino acid sequence as human beta interferon.
D000595:Amino Acid Sequence; D002478:Cells, Cultured; D005347:Fibroblasts / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007369:Interferon Inducers; D007372:Interferons / Q000096:biosynthesis* / Q000276:immunology; D008715:Methionine / Q000378:metabolism; D011070:Poly I-C / Q000494:pharmacology; D013462:Sulfur Radioisotopes / Q000378:metabolism; D014721:Vesicular stomatitis Indiana virus / Q000254:growth & development
D007106:Immune Sera; D007369:Interferon Inducers; D013462:Sulfur Radioisotopes; D007372:Interferons; D008715:Methionine; D011070:Poly I-C