[Concentration of serum globulins, pregnancy globulins, immunoglobulins and estriol in retroplacental blood].
Retroplacental blood samples were received after vaginal deliveries from 22 healthy primi- and multiparae aged between 20 and 30 years. Simultaneously venous blood samples were taken immediately after delivery. Pregnancy specific beta 1-glycoprotein (SP1), pregnancy associated alpha 2-glycoprotein (PZ), immunoglobulins G, M, A, secretory immunoglobulin A (S-IgA), alpha 2-macroglobulin (AMG) and unconjugated estriol were estimated quantitatively in venous as well as in retroplacental blood samples. The concentrations of SP1 in retroplacental blood were significantly lower compared with concentrations in venous blood, whereas estriol concentrations were significantly higher in retroplacental blood. All other factors differed not significantly. Only the IgM concentrations correlated in venous and retroplacental blood samples. The percentages of estimated proteins related to total protein content showed similar proportions in venous as well as in retroplacental blood. The relative protein content of SP1 was significantly lower in retroplacental blood than venous blood samples. The percentage of PZ was significantly higher in retroplacental blood. Among other things these increased concentrations of estriol and PZ in retroplacental blood be able to prevent the rejection of the trophoblast by the maternal endometrium.
D000328:Adult; D004964:Estriol / Q000097:blood*; D005260:Female; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D010920:Placenta; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000097:blood*; D000511:alpha-Macroglobulins / Q000032:analysis*
D006023:Glycoproteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D011257:Pregnancy Proteins; D000511:alpha-Macroglobulins; D004964:Estriol
Zur Konzentration einiger Serum-, Schwangerschafts- und Immunglobuline sowie Ostriol im Retroplazentarblut.