[Successive replacement of fatal blood loss in dogs with polyglucin and perfluorocarbon emulsion].
The authors studied the hemodynamics and gaseous exchange in dogs after successive replacement of lethal hemorrhage (50 ml/kg bw) by polyglucin and perfluorocarbon emulsion (24 vol/%). The main hemodynamic parameters got recovered and were maintained at the level approaching the initial one during the entire observation period. After blood replacement the pO2 in the artery rose to 500 mmHg, that in the vein to 120 mmHg. The oxygen volume in the blood increased by 3 vol/% on the average. Oxygen consumption also rose. All the animals survived.
D000818:Animals; D001784:Blood Gas Analysis; D001802:Blood Substitutes / Q000627:therapeutic use*; D003911:Dextrans / Q000627:therapeutic use*; D004285:Dogs; D004655:Emulsions; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use*; D006439:Hemodynamics; D006470:Hemorrhage / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D013997:Time Factors
D001802:Blood Substitutes; D003911:Dextrans; D004655:Emulsions; D005466:Fluorocarbons; D010100:Oxygen
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