Systemic arterial compliance in patients with non obstructive cardiomyopathy (NOCM), and coronary artery disease (CAD).
Arterial compliance had been estimated in three groups of patients: control, NOCM, and CAD, from analysis of the arterial pressure curve. In the three groups, a simple first order Winkessel model had been validated during normal and post extrasystolic beats. The measured arterial compliance depends mainly on i the diastolic pressure, ii, the mechanical properties of the aorta and major arteries. For the same range of age and diastolic pressure, the arterial compliance was not significantly different in the three groups of patients. Because of the significant variations of the arterial compliance during slight modifications of the diastolic pressure, the lack of difference in the compliance of control, NOCM, and CAD patients may be attributed to similar arterial mechanical properties.
D000328:Adult; D001158:Arteries / Q000503:physiopathology*; D005117:Cardiac Complexes, Premature / Q000503:physiopathology; D009202:Cardiomyopathies / Q000503:physiopathology*; D003187:Compliance; D003327:Coronary Disease / Q000503:physiopathology*; D003971:Diastole; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014655:Vascular Resistance