title: [Activity of glycogen-splitting enzymes in the bones of rats after a flight on Cosmos-1129].
abstract: In order to study the effect of weightlessness on metabolic processes in the bone organic matrix, alpha-amylase and aldolase activities in the ulnar bone of rats flown on Cosmos-1129 were measured. The activity of alpha-amylase and especially of aldolase was increased 6-10 hours after flight. The enzymic changes were the greatest in the animals exposed to weightlessness. The postflight exposure of the rats of the three experimental groups to immobilization produced different changes in the activity of the glycogen-splitting enzymes: it was either stimulated or inhibited. The findings suggest that the enzymes involved in glycogen splitting in the bone organic matrix of rats flown for 18.5 days probably aim at eliminating the adverse effects of weightlessness.
mesh_terms: D000681:Amylases / Q000378:metabolism*; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013026:Space Flight; D013997:Time Factors; D000516:alpha-Amylases / Q000378:metabolism*
chemical_list: D006003:Glycogen; D000681:Amylases; D000516:alpha-Amylases; D005634:Fructose-Bisphosphate Aldolase
vernacular_title: Aktivnost glikogenrasshchepliaiushchikh fermentov v kostiakh krys posle poleta na biosputnike "Kosmos-1129".