Cytologic findings in oral contraceptive users among Israeli Jewish women.
A group of 3,317 Jewish Israeli women were studied to evaluate a possible correlation between previous and recent oral contraceptive usage and cervical cytopathologic findings in Papanicolaou smears. A positive correlation was established between oral contraceptive usage and the occurrence of inflammatory findings: the rate of inflammatory changes depended on the length of usage, with a time lapse of at least one year preceding the appearance of such inflammatory changes. The cessation of oral contraceptive usage was associated with a decrease in the rate of inflammatory findings. No cases of cervical intraepithelial neoplasia or malignancy were found.
D000293:Adolescent; D000328:Adult; D002455:Cell Division; D002584:Cervix Uteri / Q000166:cytology / Q000473:pathology* / Q000503:physiopathology; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D007557:Israel; D007585:Jews; D012725:Sexual Behavior; D013194:Staining and Labeling / Q000379:methods; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000209:etiology / Q000473:pathology
D003276:Contraceptives, Oral