Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence.
DNA sequences complementary to the Torpedo californica electroplax mRNA coding for the alpha-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of the cloned cDNA indicates that the precursor consists of 461 amino acids including a prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic determinants on the alpha-subunit molecule are discussed.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D000939:Epitopes; D012333:RNA, Messenger; D011950:Receptors, Cholinergic / Q000235:genetics*; D014101:Torpedo / Q000235:genetics*
D000939:Epitopes; D012333:RNA, Messenger; D011950:Receptors, Cholinergic; D004247:DNA