Irradiation and bleomycin in the treatment of inoperable vulval carcinoma.
Fifteen patients with inoperable squamous cell carcinoma of the vulva were treated with Bleomycin and irradiation. Only 2 patients were also treated with vulvectomy and bilateral lymphadenectomy 2 weeks later. One patients survived more than 4 years without signs of recurrence, another survived 2 1/2 years and 2 more 18 and 12 months respectively. The rest died less than 6 months after the treatment. Three patients developed signs of lung fibrosis. Bleomycin and irradiation may render a tumor operable, but in most cases this regime merely aims at palliation.
D000368:Aged; D001761:Bleomycin / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D011379:Prognosis; D011879:Radiotherapy Dosage; D014844:Vulva / Q000601:surgery; D014846:Vulvar Neoplasms / Q000401:mortality / Q000628:therapy*
D001761:Bleomycin