Comparative antigenic structure of carbonic anhydrases CA I and CA II from human and mammalian origin.
1. Isolated carbonic anhydrases CA I and CA II from different species (man, ox, sheep, pig, dog and rat) have been analyzed by immunodiffusion techniques using rabbit specific CA I or CA II antisera. 2. Immunodiffusion shows the absence of cross-reactivity between CA I and CA II isoenzymes. 3. Common antigenic determinants (cross-reactivities) were evidenced between the CA I of the different species under study. 4. To the contrary, cross-reactivity between CA II of the species mentioned above, can clearly be demonstrated only between bovine and sheep CA II.
D000818:Animals; D002256:Carbonic Anhydrases / Q000097:blood / Q000276:immunology*; D002417:Cattle; D003429:Cross Reactions; D004285:Dogs; D000939:Epitopes / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D051381:Rats; D012417:Rumen / Q000201:enzymology; D012756:Sheep; D013552:Swine
D000939:Epitopes; D002256:Carbonic Anhydrases