Bronchial rupture as a complication of response to combination chemotherapy in metastatic testicular carcinoma.
Chemotherapy for a metastatic germ cell tumor of the testis was complicated by a life-threatening bronchial rupture secondary to lysis of an endobronchial tumor. Subsequent chemotherapy was delayed because of this complication. Other pulmonary complications of chemotherapy-induced tumor lysis, including abscess formation, empyema and pneumothorax, are discussed.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D001982:Bronchial Diseases / Q000209:etiology*; D002945:Cisplatin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology / Q000556:secondary*; D009336:Necrosis; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D011014:Pneumonia / Q000209:etiology*; D012422:Rupture, Spontaneous; D013736:Testicular Neoplasms / Q000188:drug therapy*; D014747:Vinblastine / Q000008:administration & dosage
D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin