[Scintigraphy using labeled bleomycin and lung neoplasms].
Bleomycin is the term for a group of antibiotics produced by cultures of the fungus Streptomyces verticulus, the anti-tumor cell potential of which was shown by Umezawa. Use of this property as a tumor specific marker radiolabelled with cobalt-57 was recognized by Renault in 1971. Since then there have been numerous publications concerning the good sensitivity of this type of study in the detection of neoplasms. Our department is currently investigating the sensitivity and specificity of this technique for the detection of pulmonary tumors. We describe here two typical cases illustrating the interest of this method in the diagnosis and staging of lung cancer.
D000368:Aged; D001761:Bleomycin; D003037:Cobalt Radioisotopes; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
D003037:Cobalt Radioisotopes; D001761:Bleomycin
Scintigraphie à la bléomycine marquée et néoplasie pulmonaire.