[Preparation and characterization of an antithrombin III concentrate].
Tri-calciumphosphate was found to have not only a known adsorption capacity for factors of the prothrombin complex, but also for antithrombin III. Depending on the inserted blood stabilizer the human plasma fractions Cohn I, PPSB and antithrombin III may be isolated from the same initial material in the area of the transfusion service. Enriching antithrombin III is achieved by a three-stage procedure under aseptic conditions in a closed system. Liberating antithrombin III from calciumphosphate is made with care without using any concentrated salt solutions.
D000327:Adsorption; D000990:Antithrombin III / Q000302:isolation & purification*; D002130:Calcium Phosphates; D006801:Humans; D008722:Methods
D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D000990:Antithrombin III; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous
Herstellung und Charakterisierung eines Antithrombin-III-Konzentrates.