[Effect of a single ethanol administration on the behavior and the RNA-synthesizing activity of the cell nuclei of the cerebral cortex of the rat].
A single intraperitoneal injection of ethanol (2 g/kg) disturbed the learning and performance of one trial passive avoidance task and decreased (by 14 %) the level of RNA-synthesizing activity of brain cortical synaptosomes in rats. The data obtained are discussed in accordance with the hypothesis that ethanol affects synaptic transmission in the central nervous system.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002467:Cell Nucleus / Q000187:drug effects* / Q000378:metabolism; D002540:Cerebral Cortex / Q000187:drug effects* / Q000378:metabolism; D003214:Conditioning, Classical / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000008:administration & dosage*; D008297:Male; D008568:Memory / Q000187:drug effects; D012313:RNA / Q000096:biosynthesis*; D051381:Rats
D000431:Ethanol; D012313:RNA
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