The influence of phagocytosis on transcobalamins releasing from polymorphonuclear granulocytes of patients with Hodgkin's disease.
The release of transcobalamins I and III (TC-I/III) during phagocytosis of latex particles from polymorphonuclear granulocytes of healthy persons and patients with Hodgkin's disease were studied. Our investigations indicate that phagocytosis stimulates the release of these proteins in both examined groups. The values of the patients with I and II stage of disease did not differ distinctly from the results of healthy persons. This preliminary studies will be extended to patients with advanced Hodgkin's disease. In addition, our results may suggest the influence of phagocytosis on the activation of TC-I/III synthesis.
D001798:Blood Proteins / Q000378:metabolism*; D006689:Hodgkin Disease / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils / Q000378:metabolism* / Q000502:physiology; D010587:Phagocytosis; D014155:Transcobalamins / Q000378:metabolism*
D001798:Blood Proteins; D014155:Transcobalamins