Hemoglobin enhancement of experimental infection of mice with Pasteurella haemolytica.
A 2% hemoglobin preparation injected into mice along with Pasteurella haemolytica culture was found to be as good an enhancer of virulence as a 7% swine gastric mucin preparation. The hemoglobin preparation was easier to prepare and was less toxic than mucin for mice when injected intraperitoneally.
D000818:Animals; D002417:Cattle / Q000382:microbiology; D002645:Chickens / Q000382:microbiology; D004195:Disease Models, Animal; D005752:Gastric Mucins / Q000494:pharmacology; D006454:Hemoglobins; D007501:Iron / Q000494:pharmacology; D008168:Lung / Q000382:microbiology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000382:microbiology*; D010325:Pasteurella / Q000472:pathogenicity*; D010326:Pasteurella Infections / Q000382:microbiology / Q000662:veterinary*; D012376:Rodent Diseases / Q000382:microbiology*; D012756:Sheep / Q000382:microbiology; D013552:Swine; D014774:Virulence / Q000187:drug effects
D005752:Gastric Mucins; D006454:Hemoglobins; D007501:Iron