title: A study of the mechanism of the toluidine blue dye test.
abstract: Toluidine blue is commonly used by endoscopists as a screening test for squamous cell carcinoma. Little information is available on the mechanism of vital staining as it is not preserved by conventional fixation. By using a simple method to stabilize toluidine blue, the authors were able to study the action of the dye under the light and electron microscope. The findings are reported.
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000378:metabolism; D004938:Esophageal Neoplasms / Q000175:diagnosis*; D004947:Esophagus / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D009092:Mucous Membrane / Q000378:metabolism / Q000648:ultrastructure; D013194:Staining and Labeling / Q000379:methods; D014048:Tolonium Chloride / Q000378:metabolism
chemical_list: D014048:Tolonium Chloride