Somatostatin-28-like immunoreactivity in the stomach.
Localization of somatostatin-28 and somatostatin-14 immunoreactive cells in the human, canine and cat's stomach was studied by an indirect immunoperoxidase method using somatostatin-14 antisera and specific antisera against somatostatin-28. The somatostatin-28 immunoreactive cells belonged to the endocrine-like cells of the fundic glands and pyloric antrum of the human, canine and cat's stomach. These cells were identical to somatostatin-14 ones. Since immunocytochemical cross-reaction between specific antisera against somatostatin-28 and somatostatin-14 was not found, it was suggested that the coexistence of N-terminal amino acid sequence of somatostatin-28 and somatostatin-14 in one and the same cell seemed to be most likely. Thus, it seems probable that somatostatin-28 originally isolated from porcine and ovine tissues may be constantly present in other mammals.
D000818:Animals; D002415:Cats; D004285:Dogs; D000939:Epitopes / Q000276:immunology; D005748:Gastric Fundus / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D011706:Pyloric Antrum / Q000032:analysis; D013004:Somatostatin / Q000032:analysis* / Q000276:immunology; D053561:Somatostatin-28; D013270:Stomach / Q000032:analysis* / Q000166:cytology
D000939:Epitopes; D013004:Somatostatin; D053561:Somatostatin-28