[Vesiculation of erythrocytes. 4. Quantification of vesiculation rates in standard fluid preservation].
The quantity of erythrocytic vesicles was estimated, which were produced after 6 weeks banking of ACD/AG and CPD/AG blood samples. The analytical and morphological dates of these vesicles allow calculation leading to the following conclusions: 1. After 6 weeks storage under blood banking conditions about 210 vesicles per erythrocyte were formed. 2. The vesiculation may serve as a possible explanation for storage dependent losses of sialic acid as well as phospholipids. 3. The vesiculation is accompanied by a reduction of the surface/volume ratio of the erythrocytes. This may be an important fact regarding the elimination of a part of stored cells via decreasing deformability of the red blood cells.
D001793:Blood Preservation; D004912:Erythrocytes / Q000378:metabolism / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D010743:Phospholipids / Q000097:blood; D012794:Sialic Acids / Q000097:blood; D013997:Time Factors
D010743:Phospholipids; D012794:Sialic Acids
Vesikulation von Erythrozyten. 4. Quantifizierung der Vesikulationsraten von Standardfluüssigkonserven.