Axonal transport dysfunction in dystrophia myotonica.
Axonal transport of acetylcholinesterase (AChE) was measured in the median and sural nerves of a subject who suffered from dystrophia myotonica and in a control subject. It was found that the basal activity of AChE was increased in myotonic nerves while its proximodistal transport was inhibited.
D000110:Acetylcholinesterase / Q000032:analysis; D000328:Adult; D001370:Axonal Transport; D001369:Axons / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000032:analysis / Q000473:pathology; D009223:Myotonic Dystrophy / Q000473:pathology*; D013497:Sural Nerve / Q000032:analysis / Q000473:pathology
D000110:Acetylcholinesterase