Lymphocytotoxic donor-specific response to fresh and stored blood. An experiment in immunosuppressed rhesus monkies (brief communication).
Transfusion of stored blood has been found to decrease the rate of antibody formation. Antigen immunogenicity and the recipient's immunoresponsiveness have a major role in the fate of the allograft. The combined effect of low immunogenicity and depressed responsiveness has been studied.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000918:Antibody Specificity / Q000187:drug effects*; D001379:Azathioprine / Q000494:pharmacology*; D001793:Blood Preservation; D001803:Blood Transfusion; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D000939:Epitopes / Q000276:immunology; D005260:Female; D008253:Macaca mulatta; D008297:Male; D011239:Prednisolone / Q000494:pharmacology*; D013602:T-Lymphocytes, Cytotoxic / Q000187:drug effects
D000939:Epitopes; D011239:Prednisolone; D001379:Azathioprine