title: [Behavior of various blood coagulation and hemorrheological parameters in arteriosclerotic vascular disease of the lower legs].
abstract: Red blood cell filterability was compared with some blood coagulation parameters in 50 patients suffering from atherosclerosis obliterans of lower limbs at stages II, III and IV. The reduced red blood cell filterability correlated positively with the stage of the arterial disease (r = 0.8185), with levels of plasma fibrinogen (r = 0.8366) and with the euglobulin lysis time (r = 0.8124), while negative correlations with platelet reactivity threshold (r = 0.6928) and with antithrombin III activity (r = 0.6557) were found. The authors believe that in the therapy of these vascular diseases it is necessary to modify the reduced red blood cell filterability together with the blood coagulation order.
mesh_terms: D000990:Antithrombin III / Q000032:analysis; D001162:Arteriosclerosis Obliterans / Q000097:blood*; D001779:Blood Coagulation Factors / Q000032:analysis*; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D012712:Serum Globulins / Q000378:metabolism; D014462:Ultrafiltration; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
chemical_list: D001779:Blood Coagulation Factors; D012712:Serum Globulins; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D000990:Antithrombin III; D005340:Fibrinogen
vernacular_title: Comportamento di alcuni parametri emocoagulativi ed emoreologici nelle vasculopatie arteriosclerotiche degli arti inferiori.