title: [Detection of influenza virus C antibodies in the gamma globulins and native sera of children].
abstract: Influenza C virus has been found to be sufficiently widely prevalent in the human population of the USSR. Our evidence indicates its circulation in different climatic zones of the USSR. It has first been shown that the concept of "original antigenic sin" formulated by T. Francis for influenza A and B viruses is applicable for the evaluation of the immune response to infection with different influenza C virus strains. Our evidence allows an age-group of children most susceptible to influenza C virus infection to be distinguished and a preparation for prevention and treatment of this infection proposed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D006385:Hemagglutination Inhibition Tests; D006462:Hemolytic Plaque Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D009980:Influenza A virus / Q000276:immunology; D009981:Influenza B virus / Q000276:immunology; D009500:Neutralization Tests; D009975:Orthomyxoviridae / Q000276:immunology*; D014586:USSR; D005719:gamma-Globulins / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D005719:gamma-Globulins
vernacular_title: Obnaruzhenie antitel k virusu grippa C v gamma-globulinakh i nativnykh syvorotkakh deteĭ.