Membrane proteins in hereditary spherocytosis, elliptocytosis and stomatocytosis.
Cell membrane proteins of patients with hereditary spherocytosis, elliptocytosis and stomatocytosis were analyzed by SDS acrylamide gel electrophoresis. From 7 patients with hereditary spherocytosis only one can be supposed to have a reduction of a band with a molecular weight of about 80,000 daltons. 3 members of a family with hereditary elliptocytosis and 1 patient with hereditary stomatocytosis did not differ from the donors. The question of the nature of membrane defect in haemolytic anaemias could not be answered by the results obtained.
D004612:Elliptocytosis, Hereditary / Q000097:blood*; D004910:Erythrocyte Membrane / Q000032:analysis; D004913:Erythrocytes, Abnormal / Q000032:analysis*; D006801:Humans; D008565:Membrane Proteins / Q000097:blood* / Q000235:genetics; D013103:Spherocytosis, Hereditary / Q000097:blood*
D008565:Membrane Proteins