[Salivary lysozyme, immunoglobulins and beta 2-microglobulin in Gougerot-Sjögren syndrome].
Lysozyme (LZM), immunoglobulins and beta 2-microglobulin concentrations were measured in the saliva of 79 patients with primary (n = 29) or secondary (n = 50) Sjögren's syndrome and in a control population. beta 2-microglobulin and immunoglobulins A, G and M concentrations were higher, and LZM concentrations lower than in controls. A significant correlation was established between LZM and immunoglobulins, but no correlation was found between immunoglobulins and beta 2-microglobulin, nor between the latter and LZM. These results indicate that salivary LZM concentration may be of value in the diagnosis of Sjögren's syndrome.
D000328:Adult; D000368:Aged; D001609:Beta-Globulins / Q000032:analysis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008875:Middle Aged; D009113:Muramidase / Q000032:analysis*; D012463:Saliva / Q000032:analysis*; D012859:Sjogren's Syndrome / Q000175:diagnosis*; D001613:beta 2-Microglobulin / Q000032:analysis*
D001609:Beta-Globulins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D001613:beta 2-Microglobulin; D009113:Muramidase
Lysozyme, immunoglobulines et beta 2 microglobuline salivaire au cours du syndrome de Gougerot-Sjögren.