title: Clinical experience with fibrin glue for local bleeding control and sealing of vascular prostheses.
abstract: This report concerns our clinical experience with fibrin glue for local bleeding control and for sealing of vascular prostheses. Hemostasis could be achieved in 90% of 124 applications of the glue under different indications. Local application of fibrin adhesive is recommended in all types of bleeding difficult either to approach or control by conventional surgical technique. Complete sealing of low pore vascular grafts could be obtained in all operations under extracorporeal circulation and full heparinization. Highly porous grafts sealed with fibrin glue also were explored under conditions thus far requiring tightly woven grafts.
mesh_terms: D001011:Aorta / Q000601:surgery; D001807:Blood Vessel Prosthesis; D006348:Cardiac Surgical Procedures / Q000379:methods; D013504:Cardiovascular Surgical Procedures; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D006488:Hemostasis, Surgical; D006489:Hemostatic Techniques; D006801:Humans; D011093:Polyethylene Terephthalates; D013917:Thrombin / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D011093:Polyethylene Terephthalates; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin