Pregnancy and porphyria cutanea tarda.
A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy which was normal. Her hormone analytic values including estrogens corresponded to normal values in pregnancy. Venesections had a beneficial affect on her condition.
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D003280:Contraceptives, Oral, Synthetic / Q000009:adverse effects; D004997:Ethinyl Estradiol / Q000009:adverse effects; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006801:Humans; D009644:Norgestrel / Q000009:adverse effects; D011164:Porphyrias / Q000139:chemically induced*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D012871:Skin Diseases / Q000139:chemically induced*
D003280:Contraceptives, Oral, Synthetic; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination