[Extension of the rosette test in the estimation of TAA-binding cells in breast cancer and mastopathy patients].
The antigen specific rosette test was used for the evaluation of a specific sensibilization of a tumour bearer to TAA. The frequency of the rosettes formed by peripheral blood leucocytes of breast carcinoma patients with antigen-coupled particles is significantly higher than that produced by leucocytes of normal donors. Following operation normally the number of TAA specific rosettes decrease, in 4 cases with recidives we found high numbers of TAA binding cells. In another 11/98 patients following ablatio mammae later than half a year we found positive test results and also in 17/60 patients with mastopathy. The clinical relevance of these results must be proofed in further investigations.
D000951:Antigens, Neoplasm / Q000276:immunology*; D001941:Breast Diseases / Q000276:immunology; D001943:Breast Neoplasms / Q000276:immunology* / Q000601:surgery; D000939:Epitopes; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D011946:Receptors, Antigen / Q000032:analysis*; D012397:Rosette Formation / Q000379:methods*
D000951:Antigens, Neoplasm; D000939:Epitopes; D011946:Receptors, Antigen
Einsatz des Rosettentests zur Bestimmung TAA-bindender Zellen in Mammakarzinompatienten und Patienten mit Mastopathie.