[Radioimmunological monitoring of the treatment of malignant neoplasms in childhood].
In 56 cases of children with tumours, the level of alpha-fetoprotein (AFP) was established with radio-immunological method. There were 15 children with neuroblastoma, 13 with ovarian tumours, 14 with sacro-coccygeal tumours, 7 with tumours of liver and 7 with tumours of testis. The level of AFP was elevated in all children with hepatoblastoma, carcinoma embryonale, and malignant teratoma. Monitoring was performed in 15 children with tumours mentioned above. Usefulness of evaluation of AFP level in blood serum in these tumours has been confirmed by diagnosis. In effective treatment of these tumours, AFP level has fallen down to normal. Its rising up again prognosed tumour's relapse several months before.
D001859:Bone Neoplasms / Q000628:therapy; D006528:Carcinoma, Hepatocellular / Q000628:therapy; D002648:Child; D002822:Choriocarcinoma / Q000628:therapy; D004407:Dysgerminoma / Q000628:therapy; D005260:Female; D006106:Granulosa Cell Tumor / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy; D008297:Male; D008991:Monitoring, Physiologic; D009369:Neoplasms / Q000628:therapy*; D009423:Nervous System Neoplasms / Q000628:therapy; D010051:Ovarian Neoplasms / Q000628:therapy; D011247:Pregnancy; D011863:Radioimmunoassay; D013564:Sympathetic Nervous System; D013724:Teratoma / Q000628:therapy; D013736:Testicular Neoplasms / Q000628:therapy; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins
Radioimmunologiczne monitorowanie leczenia nowotworów złośliwych wieku dzieciecego.