title: Effect of grenz rays on Langerhans' cells in human epidermis.
abstract: In order to investigate the effect of grenz rays on Langerhans' cells in human epidermis, five healthy volunteers were treated with a single dose of 4 gray of grenz rays on a limited area of buttock skin. Biopsies were obtained before irradiation and from the irradiated site 30 min, 6 hours, 24 hours, 1 week and 3 weeks after X-ray therapy. There was a slight reduction after 30 min and a very pronounced reduction of OKT-6 positive cells regarded as Langerhans' cells, 1 and 3 weeks after irradiation.
mesh_terms: D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000528:radiation effects; D002452:Cell Count; D004817:Epidermis / Q000528:radiation effects*; D005260:Female; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged
chemical_list: D000911:Antibodies, Monoclonal; D000954:Antigens, Surface