Pulsion intubation v. restrosternal gastric bypass for palliation of unresectable carcinoma of the upper thoracic oesophagus.
The optimum method of restoring the ability to swallow in patients with oesophageal carcinoma remains controversial. This prospective randomized study evaluates the palliative potential of pulsion intubation v. retrosternal gastric bypass of the excluded oesophagus in 106 patients with unresectable carcinoma; 55 patients were intubated and 51 patients treated by gastric bypass. The operative mortality and morbidity, palliation of dysphagia and postoperative nutritional status were compared in the 2 groups. Intubation resulted in 3 deaths (5.5 per cent) and gastric bypass in 4 deaths (7.8 per cent). Intubation was complicated by chest infection in 13 patients (24 per cent) but complications related to the procedure occurred in only 5 patients and included tube migration (2), respiratory obstruction (1), bleeding (2) and oesophageal perforation (1). Gastric bypass was complicated by chest infection in 14 patients (27 per cent), but procedure-related complications were common and included pneumothorax (3), wound infection (6), subphrenic abscess (2), anastomotic leak (5) and purulent neck discharge (3). Palliation of dysphagia was achieved in 93 per cent of patients following intubation and 92 per cent of patients following bypass. Nutritional status improved more rapidly following bypass. Nutritional status improved more rapidly following intubation. Pulsion intubation is the preferred palliative procedure because of fewer complications and a lesser degree of postoperative catabolism.
D000328:Adult; D000368:Aged; D003680:Deglutition Disorders / Q000628:therapy; D004938:Esophageal Neoplasms / Q000628:therapy*; D004947:Esophagus / Q000601:surgery*; D005260:Female; D006801:Humans; D007440:Intubation / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D010166:Palliative Care / Q000379:methods*; D011183:Postoperative Complications / Q000401:mortality; D011446:Prospective Studies; D011897:Random Allocation; D013270:Stomach / Q000601:surgery*