Four subfractions of amniotic fluid AFP identified by lentil lectin crossed-line affinity immunoelectrophoresis.
The subfraction of AFP was examined in 11 amniotic fluids at 43-121 days of gestation by lentil lectin crossed-line affinity immunoelectrophoresis. AFP in the amniotic fluid could be separated into four subfractions (type A, B, C, and D) according to reactivity with lentil lectin. Types A and C seem to be produced by the fetal liver, and types B and D by the yolk sac. However a part of type B may be synthesized in the fetal liver.
D000653:Amniotic Fluid / Q000032:analysis*; D001665:Binding Sites; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D005333:Fetus / Q000378:metabolism; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional / Q000379:methods; D037102:Lectins; D008099:Liver / Q000378:metabolism; D037121:Plant Lectins; D011247:Pregnancy; D015017:Yolk Sac / Q000378:metabolism; D000509:alpha-Fetoproteins / Q000032:analysis* / Q000096:biosynthesis / Q000145:classification
D037102:Lectins; D037121:Plant Lectins; D000509:alpha-Fetoproteins; C033619:lentil lectin; D003208:Concanavalin A