title: Electron microscopy of composite and intranuclear keratohyalin granules in geographic tongue of psoriasis.
abstract: Composite and intranuclear keratohyalin granules were observed in an electron-microscopic study of geographic tongue of psoriasis. The significance of intranuclear keratohyalin is not known, but it seems to be related to the disturbed proliferation and differentiation of keratinocytes in psoriasis.
mesh_terms: D002467:Cell Nucleus / Q000032:analysis; D003594:Cytoplasmic Granules / Q000032:analysis / Q000648:ultrastructure*; D005929:Glossitis, Benign Migratory / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007633:Keratins / Q000032:analysis*; D008854:Microscopy, Electron; D009061:Mouth Mucosa / Q000648:ultrastructure; D011565:Psoriasis / Q000378:metabolism / Q000473:pathology*; D014059:Tongue / Q000648:ultrastructure*
chemical_list: C001500:keratohyalin; D007633:Keratins