[Therapy of advanced neuroblastoma in children].
The success rate of treatment for advanced neuroblastoma in childhood is still unsatisfactory. The Austrian pediatric oncology working group since 1979 uses a chemotherapy protocol of Dimethyl-triazeno-imidazol-carboxamid, Adriamycin, N-Lost, Vincristin or modified for age and stage a combination of Dimethyl-triazeno-imidazol-carboxamid, Adriamycin, N-Lost, Vincristin, Cyclophosphamide and Cis-platinum. Over a 30 month period 27 children with neuroblastoma were registered, six had a stage III, twelve a stage IV tumor. Currently 15 patients have no evidence of disease, six patients are alive with tumor, one patient with stage III and five patients with stage IV are dead.
D000008:Abdominal Neoplasms / Q000188:drug therapy; D000970:Antineoplastic Agents / Q000008:administration & dosage; D016026:Bone Marrow Transplantation; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006258:Head and Neck Neoplasms / Q000188:drug therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007372:Interferons / Q000008:administration & dosage; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000188:drug therapy* / Q000628:therapy; D009588:Nitrogen Mustard Compounds / Q000008:administration & dosage; D011379:Prognosis; D013899:Thoracic Neoplasms / Q000188:drug therapy; D014750:Vincristine / Q000008:administration & dosage
D000970:Antineoplastic Agents; D009588:Nitrogen Mustard Compounds; D014750:Vincristine; D003606:Dacarbazine; D004317:Doxorubicin; D003520:Cyclophosphamide; D007372:Interferons; D002945:Cisplatin
Die Therapie des fortgeschrittenen Neuroblastoms im Kindesalter.