An improved technique for sequential R-, Q- and C-banding of bone marrow chromosomes.
A procedure for the sequential staining of metaphase cells to provide R-banding, Q-banding and C-banding of chromosomes is described. The combined techniques allow more precise identification of marker chromosomes and more accurate definition of breakpoints in the consistent chromosome translocations that are associated with certain human malignancies.
D001464:Barium; D017609:Barium Compounds; D001853:Bone Marrow / Q000648:ultrastructure*; D001854:Bone Marrow Cells; D002865:Chromomycins; D002871:Chromosome Banding / Q000379:methods*; D002951:Citrates; D019343:Citric Acid; D006801:Humans; D008739:Methyl Green; D011797:Quinacrine Mustard; D013194:Staining and Labeling
D017609:Barium Compounds; D002865:Chromomycins; D002951:Citrates; C012766:barium hydroxide; D001464:Barium; D019343:Citric Acid; D011797:Quinacrine Mustard; D008739:Methyl Green