Changes in lymphocytes following mercury administration in mice. Observations under fluorescence microscopy.
Lymphocytes were stained with vital stain acridine orange. The number of lysosomes per lymphocyte was calculated using "score" test. It should be emphasized that the present paper has proved the reliability of the fluorescence microscopy method of identification of lysosomes in the lymphocytes from peripheral blood, employed for studing the toxic effect of metals.
D000165:Acridine Orange; D000818:Animals; D005260:Female; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D008247:Lysosomes / Q000187:drug effects*; D008297:Male; D008628:Mercury / Q000494:pharmacology*; D017669:Mercury Compounds; D051379:Mice; D008810:Mice, Inbred C57BL; D008856:Microscopy, Fluorescence; D009566:Nitrates / Q000494:pharmacology*; D013194:Staining and Labeling
D017669:Mercury Compounds; D009566:Nitrates; C029948:mercury nitrate; D000165:Acridine Orange; D008628:Mercury