title: [Current status of monoclonal antibodies to human melanoma and its application].
abstract: Monoclonal antibodies to human melanoma associated antigens were reviewed from the viewpoint of a target structure recognized by them. In addition, phase I evaluation of a monoclonal antibody 225.28S in man and fundamental studies of the antibody-cytotoxic agent conjugates in melanoma-bearing nude mice were described.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D000939:Epitopes; D006801:Humans; D008545:Melanoma / Q000032:analysis / Q000175:diagnosis / Q000276:immunology*; D051379:Mice; D008819:Mice, Nude; D009374:Neoplasms, Experimental / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000939:Epitopes