Granulosa-theca-cell tumour in a 17-month-old girl.
A granulosa-theca-cell tumour in a 17-month-old girl with isosexual precocity and hirsutism is described. Following removal of the tumour, pubertal signs and hirsutism gradually subsided. Serum alpha-fetoprotein was very high (1800 ng/ml) before, but not any longer detectable after the removal of the tumour and on repeated measurements for the subsequent 34 months, at which time the clinical condition of the child has been very good.
D000367:Age Factors; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006106:Granulosa Cell Tumor / Q000473:pathology*; D006801:Humans; D007223:Infant; D007986:Luteinizing Hormone / Q000097:blood; D010051:Ovarian Neoplasms / Q000473:pathology*; D011184:Postoperative Period; D013739:Testosterone / Q000097:blood; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone