Reliability of urinary monoamine and metabolite output measurements in depressed patients.
The authors measured urinary monoamines and their metabolite outputs in 12 unmedicated depressed patients. Output of 3-methoxy-4-hydroxy-phenylglycol and vanillylmandelic acid proved to be relatively stable from one sample to another. An average of at least two measures provided data with a meaningful reliability for normetanephrine, serotonin, and homovanillic acid output. Output of dopamine, norepinephrine, 5-hydroxyindoleacetic acid, and phenylethylamine was highly variable over time.
D003866:Depressive Disorder / Q000652:urine*; D004298:Dopamine / Q000652:urine; D005260:Female; D006018:Glycols / Q000652:urine*; D006719:Homovanillic Acid / Q000652:urine*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D008875:Middle Aged; D009647:Normetanephrine / Q000652:urine*; D010627:Phenethylamines / Q000652:urine; D010648:Phenylacetates / Q000652:urine*; D012701:Serotonin / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine*
D006018:Glycols; D010627:Phenethylamines; D010648:Phenylacetates; D009647:Normetanephrine; D012701:Serotonin; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D014642:Vanilmandelic Acid; D004298:Dopamine; D006719:Homovanillic Acid