title: Muscle protein synthesis and growth of two strains of chicks vaccinated for Newcastle disease and infectious bronchitis.
abstract: Rates of in vitro protein synthesis were monitored during an 8-week period in male broilers and Leghorns. The birds received vaccinations during Weeks 2 and 5 posthatching for Newcastle disease and infectious bronchitis by the administration of a standard dose of the mixed vaccine in the drinking water. Both types of birds exhibited a marked decline in the rate of protein synthesis during each week after vaccination. The decline in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) levels were not as pronounced as those for protein synthesis, but DNA concentrations did tend to reflect the protein pattern between Weeks 5 and 6. Live weight of both types of birds increased at a steady rate throughout the period, but grams of carcass protein accrued per week followed the protein synthesis rate patterns during the 8-week period. The results suggest that Leghorns are more susceptible than broilers to the stress of vaccination.
mesh_terms: D000818:Animals; D001835:Body Weight; D002645:Chickens / Q000235:genetics / Q000378:metabolism*; D003332:Coronaviridae / Q000276:immunology*; D004247:DNA / Q000378:metabolism; D001351:Infectious bronchitis virus / Q000276:immunology*; D008297:Male; D009124:Muscle Proteins / Q000096:biosynthesis*; D009132:Muscles / Q000378:metabolism; D009522:Newcastle disease virus / Q000276:immunology*; D012313:RNA / Q000378:metabolism; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000008:administration & dosage*
chemical_list: D009124:Muscle Proteins; D014765:Viral Vaccines; D012313:RNA; D004247:DNA