Monoamino-oxidase activity in rat pineal gland. Histochemical studies.
Monoamine-oxidase (MAO) activity was detected in rat pineal gland with dopamine, 5-hydroxytryptamine (5-HT), norepinephrine and tryptamine as substrates, and nitroblue tetrazolium salt as electron acceptor. Pinealocytes stained deeply when 5-HT was the substrate. Dopamine and tryptamine substrates gave similar patterns, with moderate activity in the pinealocytes. Norepinephrine reactivity was detected in the nerve-endings.
D000818:Animals; D003470:Culture Media; D004298:Dopamine / Q000494:pharmacology; D006651:Histocytochemistry / Q000379:methods; D008995:Monoamine Oxidase / Q000032:analysis*; D009580:Nitroblue Tetrazolium; D009638:Norepinephrine / Q000494:pharmacology; D009924:Organ Culture Techniques; D010870:Pineal Gland / Q000166:cytology / Q000201:enzymology*; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D013194:Staining and Labeling / Q000379:methods; D014363:Tryptamines / Q000494:pharmacology
D003470:Culture Media; D014363:Tryptamines; D009580:Nitroblue Tetrazolium; D012701:Serotonin; D008995:Monoamine Oxidase; D004298:Dopamine; D009638:Norepinephrine