Increased alpha-fetoprotein concentration in association with ileal adenocarcinoma complicating Crohn's disease.
A considerably raised serum alpha-fetoprotein concentration was found in a patient with an ileal adenocarcinoma. alpha-fetoprotein was shown in both the primary tumour and the hepatic metastases by an immunoperoxidase technique. A raised alpha-fetoprotein concentration in association with ileal adenocarcinoma has not been described previously, and it is notable that the first such case should occur as a complication of longstanding Crohn's disease.
D000230:Adenocarcinoma / Q000150:complications / Q000378:metabolism* / Q000556:secondary; D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins