[Antigenic variants among street rabies virus isolates from France, Africa, Madagascar and Asia. Preliminary results with antinucleocapsid monoclonal antibodies].
A panel of monoclonal antibodies directed against the nucleocapsid antigens of rabies virus allowed a rapid characterization of isolates by an indirect immunofluorescence test on brain smears of infected animals. Analysis of 77 isolates (71 from animals and 6 from humans) showed a great diversity. Isolates from different areas showed different patterns of reactivity. No relation was found between animal species and antigenic patterns specificity.
D000349:Africa; D000818:Animals; D000911:Antibodies, Monoclonal; D000956:Antigens, Viral / Q000235:genetics*; D001208:Asia; D002213:Capsid / Q000276:immunology; D000939:Epitopes / Q000235:genetics*; D005602:France; D014644:Genetic Variation; D006801:Humans; D008270:Madagascar; D011820:Rabies virus / Q000276:immunology* / Q000302:isolation & purification; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D000939:Epitopes
Variantes antigéniques du virus rabique: souches des rues de France, d'Afrique, de Madagascar et d'Asie. Résultats preliminaires obtenus avec des anticorps monoclonaux antinucléocapside.