A bean alpha-amylase inhibitor formulation (starch blocker) is ineffective in man.
A commercial alpha-amylase inhibitor with potent inhibitory activity in vitro was used in a randomized double-blind, cross-over clinical trial in six nonobese, healthy adult males. In these subjects, this inhibitor had no effect on the response of blood glucose, insulin, or breath hydrogen to a standardized starch meal. It is concluded that this formulation has no effect on starch digestion in humans.
D000681:Amylases / Q000037:antagonists & inhibitors*; D001786:Blood Glucose / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000378:metabolism*; D006801:Humans; D006859:Hydrogen / Q000378:metabolism; D007328:Insulin / Q000097:blood; D000516:alpha-Amylases / Q000037:antagonists & inhibitors*
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D006859:Hydrogen; D000681:Amylases; D000516:alpha-Amylases