[Reaction of anti-I auto-antibodies with erythrocytes from the pig and monkey].
Starting from 5 human sera containing anti-I cold autoagglutinins, it was possible, using adsorption/elution trials with pig's and rhesus monkey's RBC, to separate 8 anti-I antibodies because 3 of the initial sera were heterogeneous. Each of them had 2 anti-I different as regards the reactivity with the animal RBC and the anti-ID or the anti-IF reactivity. On the whole, among 8 separated fractions 1 reacted only on pig's RBC and had the characteristics of an anti-ID; 3 reacted only on rhesus monkey's RBC and were anti-IF; 4 had a cross-reactivity with pig's and monkey's RBC: 2 of them were anti-IF and 2 anti-ID. Anti-ID fixed preferably on pig's RBC and anti-IF on rhesus monkey's RBC but monkey's RBC are not entirely lacking in ID determinants and pig's RBC in IF determinants.
D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D001789:Blood Group Antigens / Q000276:immunology*; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D007048:I Blood-Group System / Q000276:immunology*; D008253:Macaca mulatta; D013552:Swine
D001323:Autoantibodies; D001789:Blood Group Antigens; D000939:Epitopes; D007048:I Blood-Group System
Réactivité des auto-anticorps anti-I avec les hématies de porc et de singe.