Illumination induces dye incorporation in photoreceptor cells.
Illumination of fly photoreceptors in the presence of the fluorescent dye Lucifer yellow initiates incorporation of the dye, which stains each cell down to its synaptic terminal. Unilluminated cells do not become stained. Experiments on animals in vivo show that selected cells can be stained without loss of viability. "Induced endocytosis" provides a plausible mechanism underlying this phenomenon.
D000818:Animals; D001369:Axons / Q000378:metabolism; D002470:Cell Survival; D004705:Endocytosis; D005110:Extracellular Space; D005260:Female; D005456:Fluorescent Dyes / Q000378:metabolism*; D006793:Houseflies / Q000378:metabolism / Q000528:radiation effects*; D007546:Isoquinolines / Q000378:metabolism*; D008027:Light; D010786:Photoreceptor Cells / Q000378:metabolism* / Q000528:radiation effects; D012160:Retina / Q000378:metabolism / Q000528:radiation effects; D013194:Staining and Labeling; D013569:Synapses / Q000378:metabolism
D005456:Fluorescent Dyes; D007546:Isoquinolines; C017475:lucifer yellow