Methods in laboratory investigation. Application of the indirect enzyme-linked immunosorbent assay microtest to the detection and surveillance of human t cell leukemia-lymphoma virus.
An ELISA assay for the detection of human T cell leukemia-lymphoma virus antibodies in human sera has been developed that has considerable advantages over previous techniques and equals the sensitivity of radioimmunoassay. Tests of normal and antibody-positive sera from leukemia patients indicate that this method should prove useful in the seroepidemiologic research for human T cell leukemia-lymphoma virus in the human population for probing the mode of its transmission and its clinical association with various T cell malignancies.
D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007945:Leukemia, Lymphoid / Q000276:immunology; D008223:Lymphoma / Q000276:immunology; D012190:Retroviridae / Q000276:immunology*; D013601:T-Lymphocytes
D000914:Antibodies, Viral; D000956:Antigens, Viral; D000939:Epitopes