Solid phase radioimmunoassay for human myelin basic protein using a monoclonal antibody.
A solid phase competitive assay for human myelin basic protein (MBP) has been developed using a monoclonal antibody to MBP. The assay has been applied to the detection of antigenic peptides derived from MBP, the measurement of anti-idiotypic antibody and the detection of MBP in human serum.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000937:Antigen-Antibody Reactions; D000961:Antilymphocyte Serum / Q000032:analysis; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D002561:Cerebrovascular Disorders / Q000276:immunology; D006801:Humans; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains; D004676:Myelin Basic Protein / Q000032:analysis* / Q000378:metabolism; D011863:Radioimmunoassay / Q000379:methods
D000911:Antibodies, Monoclonal; D000961:Antilymphocyte Serum; D007130:Immunoglobulin Idiotypes; D004676:Myelin Basic Protein