[Digital arteritis and bleomycin. Apropos of a case].
A 47-year-old patient developed severe digital arteritis after complementary bleomycin treatment following surgery for esophageal cancer. Arteriography images showed extrinsic stenosis of the digital arteries, results of other investigations suggesting development of a sclerodermic process due to bleomycin. Ischemic lesions regressed after thoracic sympathectomy. Similar cases have been well documented but cases of associated cancer and digital ischemia lacking iatrogenic features have also been reported. The pathogenic role of bleomycin appears to be established in the present case, but the possibility of the digital ischemia developing within the framework of a paraneoplasic syndrome is discussed.
D001167:Arteritis / Q000139:chemically induced*; D001761:Bleomycin / Q000009:adverse effects*; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000139:chemically induced
D001761:Bleomycin
Artérite digitale et bléomycine. A propos d'une observation.