[Determination of the antigenic specificity of the neuraminidase of influenza viruses].
The principal possibility of using beta-propiolactone-inactivated and lyophilized antigens of influenza A and B viruses and of mouse immune ascitic fluids to them for the determination of the antigenic specificity of neuraminidase has first been established. A simpler and easier method requiring no expensive reagents: inhibition of influenza virus release from erythrocytes was tested. This method is as specific as the labour-consuming and difficult test of neuraminidase activity inhibition, and allows a rapid and accurate identification of the type of neuraminidase of influenza viruses of various origins to be made.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D000939:Epitopes / Q000032:analysis*; D006389:Hemagglutinins, Viral / Q000032:analysis; D007158:Immunologic Techniques; D009980:Influenza A virus / Q000201:enzymology / Q000276:immunology*; D051379:Mice; D009439:Neuraminidase / Q000276:immunology*
D000956:Antigens, Viral; D000939:Epitopes; D006389:Hemagglutinins, Viral; D009439:Neuraminidase
Opredelenie antigennoĭ spetsifichnosti neĭraminidazy virusov grippa.