Effects of a low power laser beam guided by optic fiber on rat brain striatal monoamines and amino acids.
In vivo, helium-neon and nitrogen laser beams guided by optic fiber to rat caudate nucleus decreased concentrations of dopamine and serotonin, while distant laser radiation to frontal cortex did not affect striatal dopamine. In vitro, laser radiation to pure monoamines and amino acids decreased concentrations only of aspartic acid and norepinephrine. The effects in vivo are attributed to a combination of photolysis and altered brain metabolism.
D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D002421:Caudate Nucleus / Q000502:physiology; D003342:Corpus Striatum / Q000502:physiology*; D004298:Dopamine / Q000378:metabolism*; D005625:Frontal Lobe / Q000502:physiology; D005971:Glutamates / Q000378:metabolism; D018698:Glutamic Acid; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D007834:Lasers; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D000596:Amino Acids; D005971:Glutamates; D001224:Aspartic Acid; D012701:Serotonin; D018698:Glutamic Acid; D006897:Hydroxyindoleacetic Acid; D005680:gamma-Aminobutyric Acid; D004298:Dopamine; D009638:Norepinephrine