An electron microscope study of the cortico-pretecto-olivary projection in the cat by a combined degeneration and horseradish peroxidase tracing technique.
The anterior pretectal nucleus (PTA) of the cat was observed electron microscopically after motor cortical ablation and horseradish peroxidase (HRP) injection into the inferior olive of the same animal. Direct synaptic connections were found between degenerated cortico-pretectal axon terminals and dendrites of pretecto-olivary projection neurons retrogradely labeled with HRP in the ventrolateral part of the PTA. Therefore, this combined method revealed that the PTA is a relay station of the cortico-olivary projection.
D000818:Animals; D001370:Axonal Transport; D001921:Brain / Q000033:anatomy & histology* / Q000648:ultrastructure; D002415:Cats; D006735:Horseradish Peroxidase; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000033:anatomy & histology*; D009847:Olivary Nucleus / Q000033:anatomy & histology*; D013238:Stereotaxic Techniques; D013477:Superior Colliculi / Q000033:anatomy & histology*
D006735:Horseradish Peroxidase