title: Maternal hypertension with superimposed pre-eclampsia: effects on child development at 71/2 years.
abstract: Children born to women participating in a prospective study of hypertension during pregnancy were followed up from birth. Data on growth and development at the age of 71/2 years of 56 children whose mothers had superimposed pre-eclampsia are compared with results of 176 children whose mothers had only hypertension. Perinatal mortality in the hypertension-only group was similar to that for the hospital population in general at the time of their birth; but in the group who developed preeclampsia it was significantly higher. At the age of 71/2 years no differences were found in the frequency of health, handicap, sight and hearing problems, weight, height, head circumference, and standing and supine blood pressures. For six aspects of intellectual development children in the pre-eclampsia group had slightly higher mean scores; and in one of these, "perceptual matching' the difference was significant after adjustment had been made for confounding variables. Pre-eclampsia superimposed on hypertension does not increase the likelihood of impaired growth and development among children who survive the perinatal period.
mesh_terms: D002648:Child; D002658:Developmental Disabilities / Q000209:etiology*; D005260:Female; D005313:Fetal Death / Q000209:etiology; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007360:Intelligence; D008297:Male; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000150:complications*; D011297:Prenatal Exposure Delayed Effects; D011507:Proteinuria / Q000150:complications