title: The axon reflex flare.
abstract: The axon reflex flare is a well-described dermatologic entity with historic and diagnostic value in dermatologic practice. Recent research into the role of neuropeptide mediators has elucidated a fascinating and complex interaction between biochemistry and clinical dermatology. These principles should enhance understanding of those constant dermatologic entitites, the flare, the itch, and the wheal.
mesh_terms: D000255:Adenosine Triphosphate / Q000502:physiology; D001369:Axons / Q000502:physiology*; D003872:Dermatitis / Q000503:physiopathology; D006632:Histamine / Q000502:physiology; D006801:Humans; D007705:Kinins / Q000502:physiology; D009431:Neural Conduction; D011453:Prostaglandins / Q000502:physiology; D012018:Reflex; D013189:SRS-A / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000294:innervation / Q000503:physiopathology; D012879:Skin Physiological Phenomena; D013373:Substance P / Q000502:physiology; D014664:Vasodilation
chemical_list: D007705:Kinins; D011453:Prostaglandins; D013189:SRS-A; D013373:Substance P; D006632:Histamine; D000255:Adenosine Triphosphate