Oral granular cell myoblastoma: an immunohistochemical study.
Immunoperoxidase staining for a variety of antigens was performed on 15 cases of granula cell myoblastoma occurring within the oral tissues. All tumours gave intense intracytoplasmic granular staining for a CEA-related antigen with one rabbit antiserum to CEA (Dakopatts) whereas all were negative with a sheep antiserum to CEA (Seward). None of the tumours were positive for lysozyme, alpha 1 antitrypsin to cathepsin B whereas 12 lesions gave a granular reaction for cathepsin D. All granular cells showed a weak reaction for actin in contrast to the strong cytoplasmic staining found in smooth striated muscle and muscle derived tumours.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007889:Leiomyoma / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology*; D009379:Neoplasms, Muscle Tissue / Q000276:immunology*; D009442:Neurilemmoma / Q000276:immunology; D009455:Neurofibroma / Q000276:immunology; D013194:Staining and Labeling
D002272:Carcinoembryonic Antigen