Antiviral effects of bovine interferons on bovine respiratory tract viruses.
The antiviral effects of bovine interferons on the replication of bovine respiratory tract viruses were studied. Bovine turbinate monolayer cultures were treated with bovine interferons and challenged with several bovine herpesvirus 1 strains, bovine viral diarrhea virus, parainfluenza type 3 virus, goat respiratory syncytial virus, bovine respiratory syncytial virus, bovine adenovirus type 7, or vesicular stomatitis virus. Treatment with bovine interferons reduced viral yield for each of these viruses as compared with that of control cultures.
D000256:Adenoviridae / Q000187:drug effects; D000818:Animals; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000187:drug effects; D007242:Herpesvirus 1, Bovine / Q000187:drug effects; D007372:Interferons / Q000494:pharmacology*; D010224:Parainfluenza Virus 3, Human / Q000187:drug effects; D012136:Respiratory Syncytial Viruses / Q000187:drug effects; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects; D014779:Virus Replication / Q000187:drug effects*; D014780:Viruses / Q000187:drug effects*
D007372:Interferons