title: [Histochemical study of the pilotropic action of 1-(chloromethyl)silatrane on guinea pig skin].
abstract: Histochemical methods have disclosed that external application of 5% ointment of 1-(chlormethyl)silatran leads to an increase of the glycogen and RNA content in guinea-pig skin, reduction of the heparin content in the basal membrane and external epithelial vagina. Factors that give rise to pilotropic activity of 1-(chlormethyl)silatran are discussed.
mesh_terms: D000818:Animals; D006003:Glycogen / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006168:Guinea Pigs; D006203:Hair Preparations / Q000008:administration & dosage*; D006493:Heparin / Q000378:metabolism; D009824:Ointments; D017646:Organosilicon Compounds; D012313:RNA / Q000378:metabolism; D012825:Silicon / Q000008:administration & dosage*; D012867:Skin / Q000378:metabolism
chemical_list: D006025:Glycosaminoglycans; D006203:Hair Preparations; D009824:Ointments; D017646:Organosilicon Compounds; D012313:RNA; C033818:1-(chloromethyl)silatrane; D006493:Heparin; D006003:Glycogen; D012825:Silicon
vernacular_title: Gistokhimicheskoe izuchenie pilotropnogo deĭstviia 1-(khlormetil)silitrana na kozhu morskikh svinok.