Concentrations of 5-hydroxyindoleacetic acid and homovanillic acid in the cerebrospinal fluid of chronic therapy-resistant schizophrenics before and after hemodialysis therapy.
The concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) have been determined by high-performance liquid chromatography in samples of lumbar cerebrospinal fluid from chronic therapy-resistant schizophrenics, both before and after either inactive or active hemodialysis for 10 weeks. A reasonable test-retest reliability was found for 5-HIAA during the inactive dialysis, but this was not found during active dialysis.
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D004311:Double-Blind Method; D005260:Female; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid*; D008297:Male; D010648:Phenylacetates / Q000134:cerebrospinal fluid*; D006435:Renal Dialysis; D012559:Schizophrenia / Q000134:cerebrospinal fluid / Q000628:therapy*; D013997:Time Factors
D010648:Phenylacetates; D006897:Hydroxyindoleacetic Acid; D006719:Homovanillic Acid