Malignant schwannoma presenting as a skin mass. Confirmation by the demonstration of myelin basic protein within tumor cells.
A malignant spindle cell tumor with features of a malignant schwannoma presented as a skin mass in the neck of a 13-year-old child. The histologic diagnosis was supported by the demonstration of myelin basic protein within the atypical cells using a monoclonal antibody to myelin basic protein and an unlabelled antibody peroxidase-antiperoxidase technique.
D000293:Adolescent; D003593:Cytoplasm / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D004676:Myelin Basic Protein / Q000032:analysis*; D009333:Neck; D009442:Neurilemmoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
D004676:Myelin Basic Protein