[Interferon production by different inducers].
The rates and time course of interferon production in mice administered nine inductors of different nature were studied and compared. Use was made of the most prospective synthetic and natural polymers as well as of low-molecular preparations. It was established that polymers bring about early interferon production with a peak being reached in 4-6 hours, followed by rapid disappearance. Low-molecular inductors are marked by late interferon production, with the maximal titers attained in 24-48 hours, followed by prolonged circulation (4 days of observation).
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007369:Interferon Inducers / Q000494:pharmacology*; D007372:Interferons / Q000096:biosynthesis*; D051379:Mice; D008970:Molecular Weight; D013997:Time Factors
D007369:Interferon Inducers; D007372:Interferons
Produktsiia interferona pri ispol'zovanii induktorov raznoĭ prirody.