title: [Characteristics of hyperchromic neurons from a focus of local cortical destruction].
abstract: Using the Bernhard method of differential staining of ribonucleoproteins the sequence of neuronal destruction by a hyperchromic manner has been demonstrated in the focus of local destruction in the rat brain. This process is marked by a decrease of nuclear synthetic activity, inhibition of the nuclear-cytoplasmic transport, transition of the nucleus components to a metabolically inert state followed by the hydrolysis of the nuclear ribonucleoprotein particles, and destruction of cytoplasmic mitochondria. The processes of neuronal destruction by a hyperchromic manner are culminated in neuronophagia on the part of the oligodendroglia.
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000473:pathology; D002466:Cell Nucleolus / Q000473:pathology; D002843:Chromatin; D008297:Male; D009419:Nerve Tissue Proteins; D009474:Neurons / Q000473:pathology*; D009836:Oligodendroglia / Q000473:pathology; D051381:Rats; D012261:Ribonucleoproteins; D013003:Somatosensory Cortex / Q000293:injuries*; D013194:Staining and Labeling
chemical_list: D002843:Chromatin; D009419:Nerve Tissue Proteins; D012261:Ribonucleoproteins
vernacular_title: Kharakteristika giperkhromnykh neĭronov iz ochaga lokal'noĭ destruktsii kory.