[The effect of exogenous RNA and their fragments on yeast beta-galactosidase activity].
It is shown that a degradation level of exogenic high-polymeric RNA does not change their stimulating effect on beta-galactosidase synthesis in yeast protoplasts. Nucleoside monophosphates are a product of RNA degradation which promotes an increase in the beta-galactosidase activity. The exogenic RNA is established to act at the transcription level. RNA and its degradation products stimulate the beta-galactosidase synthesis without any effect on the intensity of the total RNA and protein synthesis in the yeast protoplasts. All mentioned permitted a conclusion that products of RNA decay participate in the regulation of the beta-galactosidase synthesis of yeast. A possible mechanism of their action is under discussion.
D005696:Galactosidases / Q000378:metabolism*; D006868:Hydrolysis; D009843:Oligoribonucleotides / Q000494:pharmacology; D015125:Oxyquinoline / Q000494:pharmacology; D012313:RNA / Q000494:pharmacology*; D012331:RNA, Fungal / Q000096:biosynthesis; D012440:Saccharomyces / Q000201:enzymology* / Q000378:metabolism; D001616:beta-Galactosidase / Q000378:metabolism*
D009843:Oligoribonucleotides; D012331:RNA, Fungal; D015125:Oxyquinoline; D012313:RNA; D005696:Galactosidases; D001616:beta-Galactosidase
Deĭstvie ékzogennykh RNK i ikh fragmentov na aktivnost' beta-galaktozidazy drozhzheĭ.