title: [Dynamics of nucleic acid metabolism in the bone marrow and liver of rats exposed to the combined action of external gamma radiation and plutonium-239].
abstract: A combined effect of a single exposure to gamma-radiation (103.2 mC/kg) and plutonium-239 (92.5 kBq/kg body weight) caused a decrease in the total number of caryocytes and a change in the nucleic acid metabolism in rat bone marrow. At early times, the changes noted in the bone marrow, as well as in other radiosensitive tissues, were induced by gamma-radiation; at later times (180-360 days), the effect was evidently produced by the incorporated plutonium. In liver tissues, the variation of all the parameters under study was less pronounced.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000378:metabolism* / Q000528:radiation effects; D004247:DNA / Q000378:metabolism*; D005720:Gamma Rays; D008099:Liver / Q000378:metabolism* / Q000528:radiation effects; D008297:Male; D011005:Plutonium; D012313:RNA / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D011005:Plutonium; D012313:RNA; D004247:DNA
vernacular_title: Dinamika obmena nukleinovykh kislot v kostnom mozge i pecheni krys pri sochetannom vozdeĭstvii vneshnego gamma-oblucheniia i plutoniia-239.