title: Analysis of the genome structure of influenza A virus strains isolated during the epidemics of 1977-1980.
abstract: The genome structure of different A(H1N1) and A(H3N2) influenza virus strains isolated from 1977 to 1980 was analysed by electrophoresis of single-stranded RNA and of the double-stranded RNA obtained by hybridization with complementary RNA of the A/Stavropol 188/79 (H3N2) strain. The differences in genome structure are insignificant within the A(H1N1) subtype, and considerable (involving almost all the 8 RNA fragments) between the two A(H3N2) strains (A/Texas 1/77 and A/Stavropol 188/79). The great differences between the genomes of A(H1N1) and A(H3N2) strains do not exclude certain genetic relationships between these viruses.
mesh_terms: D001483:Base Sequence; D004196:Disease Outbreaks; D004586:Electrophoresis; D005814:Genes, Viral; D006801:Humans; D009980:Influenza A virus / Q000145:classification / Q000235:genetics*; D007251:Influenza, Human / Q000382:microbiology*; D009693:Nucleic Acid Hybridization; D012313:RNA; D012367:RNA, Viral; D012703:Serotyping
chemical_list: D012367:RNA, Viral; D012313:RNA