title: [Immunological analysis of the chronological sequence of the shift in the antigenic determinants of influenza virus A (H1N1) hemagglutinins].
abstract: The study of the antigenic composition of influenza A (H1N1) viruses of two circulation periods, 1933-1957 and 1977-1981, by the method of selective adsorption of highly active antihemagglutinating sera revealed the ways of antigenic variability of drift variants. The antigenic composition of the hemagglutinin of H1N1 viruses of the second circulation period was found to be similar to that of H1N1 viruses isolated in 1950-1953.
mesh_terms: D000327:Adsorption; D000939:Epitopes / Q000032:analysis*; D014644:Genetic Variation; D006385:Hemagglutination Inhibition Tests; D006389:Hemagglutinins, Viral / Q000032:analysis*; D053118:Influenza A Virus, H1N1 Subtype; D009980:Influenza A virus / Q000276:immunology*; D013997:Time Factors
chemical_list: D000939:Epitopes; D006389:Hemagglutinins, Viral
vernacular_title: Immunologicheskiĭ analiz khronologicheskoĭ posledovatel'nosti smeny antigennykh determinant gemaggliutininov virusa grippa A (H1N1).