Amino acid sequence homology between the C3 chain of rat prostatic steroid binding protein and human alpha 2-macroglobulin.
Using a computer program designed to detect evolutionary relationships between proteins, I find that exon 2 of the C3 chain of rat prostatic steroid binding protein has amino acid sequence homology with residues 1058-1119 of the protease inhibitor alpha 2-macroglobulin. This finding suggests interesting approaches for studying the functions of these proteins.
D000595:Amino Acid Sequence; D000727:Androgen-Binding Protein / Q000235:genetics*; D001483:Base Sequence; D005075:Biological Evolution; D002352:Carrier Proteins / Q000235:genetics*; D003201:Computers; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D049488:Phosphatidylethanolamine Binding Protein; D060789:Prostatein; D060765:Secretoglobins; D014598:Uteroglobin; D000511:alpha-Macroglobulins / Q000235:genetics*; D060788:Mammaglobin B
D000727:Androgen-Binding Protein; D002352:Carrier Proteins; D046911:Macromolecular Substances; D049488:Phosphatidylethanolamine Binding Protein; D060789:Prostatein; D060765:Secretoglobins; D014598:Uteroglobin; D000511:alpha-Macroglobulins; C511482:PEBP1 protein, human; C511484:Scgb1d2 protein, rat; C511483:Scgb1d4 protein, rat; C556468:Scgb2a1 protein, rat; D060788:Mammaglobin B