[Comparative study of the immunological properties of insulins and insulin-like substances of vertebrates and invertebrates].
Comparative studies have been made on immunological properties of insulins (bovine, porcine and fish--Oncorhynchus gorbuscha, O. keta) and insulin-like substances of the mollusk Anodonta cygnea and starfish Asterias rubens in homologous and heterologous for these hormones radio-immune systems. It was concluded that each of these systems reveals in the insulins and insulin-like substances investigated the identical antigenic determinants. At the same time, low affinity of the hormones to heterologous antibodies indicates the existence of significant differences in the structure of binding sites.
D000818:Animals; D000906:Antibodies / Q000276:immunology; D000941:Antigens / Q000032:analysis; D001667:Binding, Competitive; D002417:Cattle; D000939:Epitopes / Q000032:analysis; D007328:Insulin / Q000276:immunology*; D007448:Invertebrates / Q000276:immunology*; D008974:Mollusca; D011863:Radioimmunoassay; D012487:Salmonidae; D013045:Species Specificity; D013215:Starfish; D013552:Swine; D014714:Vertebrates / Q000276:immunology*
D000906:Antibodies; D000941:Antigens; D000939:Epitopes; D007328:Insulin
Sravnitel'noe issledocanie immunologicheskikh svoĭstv insulinov i insulinopodobnykh veshchestv u pozvonochnykh i bespozvonochnykh.