C-cell follicles of canine thyroid glands studied by PAS reaction and electron microscopy.
Small follicles composed solely of C cells were occasionally observed in large C cell groups of dog thyroid glands. The lumina of C-cell follicles were filled with, or contained peripheral depositions of PAS-positive amorphous material, which was similar in ultrastructural features to thyroglobulin-containing colloid in typical thyroid follicles. This indicates that C cells, in addition to secreting calcitonin, produce a glycoprotein that can be stored in the lumina of the follicles.
D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D013194:Staining and Labeling; D013961:Thyroid Gland / Q000166:cytology* / Q000648:ultrastructure