[Transduction of oncogene by retrovirus: structural alternation of a foreign DNA inserted into retrovirus].
Frequent modification such as a point mutation or a deletion of a DNA inserted into retrovirus DNA vector is observed. Activation of onco gene in retroviral genome might be caused by such mechanisms.
D000510:Alpha-Globulins / Q000235:genetics; D000818:Animals; D002472:Cell Transformation, Viral; D002645:Chickens; D004274:DNA, Recombinant; D004279:DNA, Viral / Q000235:genetics*; D005814:Genes, Viral; D005822:Genetic Vectors; D051379:Mice; D009857:Oncogenes; D012367:RNA, Viral / Q000235:genetics; D012190:Retroviridae / Q000235:genetics*; D014161:Transduction, Genetic
D000510:Alpha-Globulins; D004274:DNA, Recombinant; D004279:DNA, Viral; D012367:RNA, Viral