Immune response in thermally injured guinea-pigs treated with methisoprinol.
A series of experiments has been performed in order to evaluate the effects of methisoprinol on immune response following thermal injury. Methisoprinol treatment induced a sharp stimulation of the cell-mediated immune response in burned animals. This finding demonstrates that methisoprinol may be useful in burns to prevent infections related to immune depression.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002056:Burns / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D007111:Immunity, Cellular / Q000187:drug effects; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000627:therapeutic use*; D008297:Male
D007288:Inosine; D007542:Inosine Pranobex