Relation between pregnancy-associated plasma protein A and fetal sex and blood group.
Maternal pregnancy-associated plasma protein A (PAPP-A) concentration was estimated in 272 pregnancies. Paired samples at 34 weeks of gestation and within 48 h before delivery were compared in relation to fetal and maternal blood group and fetal sex. The PAPP-A values were significantly higher both at 34 weeks and near delivery in rhesus-negative bearers. Mothers of male babies had higher PAPP-A values near delivery but not significantly higher at 34 weeks. This supports earlier findings that some placental hormones are higher in male bearers.
D000017:ABO Blood-Group System / Q000235:genetics*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005333:Fetus; D005865:Gestational Age; D006801:Humans; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood; D011257:Pregnancy Proteins / Q000032:analysis*; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis*; D012204:Rh-Hr Blood-Group System / Q000235:genetics*; D012737:Sex Factors
D000017:ABO Blood-Group System; D011257:Pregnancy Proteins; D012204:Rh-Hr Blood-Group System; D011266:Pregnancy-Associated Plasma Protein-A