[Dexamethasone test, somatomedin level and other metabolic indices in adenoma and cancer of the prostate].
The blood levels of hydroxycorticosteroid-11 (11-HOCS) before and after dexamethasone, somatomedins, cholesterol, triglycerides, beta-lipoproteins and cholesterol of high-density lipoproteins were studied in 55 patients with prostatic adenoma and 75 cases of prostatic cancer. It was found that the hypothalamo-pituitary system is resistant to inhibition by dexamethasone in both groups, while elevation of absolute level of 11-HOCS was observed in cases of adenoma. Patients with prostatic cancer revealed a higher blood serum-somatomedin level. Triglyceride level was relatively higher, and diabetes mellitus and hyperlipidemia (type IIb and IV) were slightly more frequent in patients with prostatic adenoma. This was matched by a relatively higher level of cholesterol and more frequent hyperlipidemia type IIa in cancer patients.
D000368:Aged; D002784:Cholesterol / Q000097:blood; D003907:Dexamethasone / Q000008:administration & dosage; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000175:diagnosis; D011471:Prostatic Neoplasms / Q000097:blood* / Q000175:diagnosis; D013002:Somatomedins / Q000097:blood; D014280:Triglycerides / Q000097:blood
D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D013002:Somatomedins; D014280:Triglycerides; D003907:Dexamethasone; D002784:Cholesterol
Deksametazonovyĭ test, uroven' somatomedina i nekotorye metabolicheskie sopostavleniia pri adenome i rake predstatel'noĭ zheleze.