[Use of neurotropic agents stimulating tissue trophic processes in treating ulcerative lesions of the gastric mucosa].
The development of experimental neurogenic gastric ulcers was followed by a reduction in the noradrenaline and cAMP levels in the gastric tissue. The energy deficiency and upset nucleic metabolism were shown to underlie the structural lesions of the gastric mucosa. L-DOPA and etimizol stimulating the metabolic processes and the function of the sympathetic nervous system intensify the reparative processes during gastric ulceration.
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004247:DNA / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D004734:Energy Metabolism / Q000187:drug effects; D005042:Etimizol / Q000627:therapeutic use*; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D006168:Guinea Pigs; D007093:Imidazoles / Q000627:therapeutic use*; D007980:Levodopa / Q000627:therapeutic use*; D012313:RNA / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D013268:Stimulation, Chemical; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000378:metabolism
D000897:Anti-Ulcer Agents; D007093:Imidazoles; D007980:Levodopa; D012313:RNA; D004247:DNA; D005042:Etimizol
Primenenie neĭrotropnykh sredstv, stimuliruiushchikh tkanevye troficheskie protsessy, pri lechenii iazvennykh porazheniĭ slizistoĭ obolochki zheludka.