Changes in plasma gonadotrophins after neurotropic stress in the postnatal castrated male rat. Influence of adrenalectomy.
In 60-day-old postnatal castrated male rat, neurotropic stress increased plasma levels of LH, FSH, ACTH, corticosterone, testosterone and 17 beta-oestradiol. The possible influence of ACTH in the observed increase in plasma sex steroids was discussed. After adrenalectomy, performed at 50 days of age, neurotropic stress no longer affected plasma gonadotrophin level significantly. Adrenalectomy, raising plasma level of corticotrophin and decreasing plasma levels of testosterone and 17 beta-oestradiol, created conditions favorable to inhibition of gonadotrophin function.
D000302:Adrenal Cortex / Q000502:physiology*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000502:physiology*; D000818:Animals; D002369:Castration; D003345:Corticosterone / Q000097:blood; D004958:Estradiol / Q000097:blood; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000097:blood*; D013739:Testosterone / Q000097:blood
D006065:Gonadotropins, Pituitary; D013739:Testosterone; D004958:Estradiol; D000324:Adrenocorticotropic Hormone; D003345:Corticosterone