title: [Case report of Lyell's syndrome].
abstract: In Lyell's syndrome a toxic skin erythema is concerned which leads to the epidermal necrolysis and desquamation. An infantile and an adult form are differed; the latter is usually induced by medicaments. Two patients with apparently medicamentously induced Lyell's syndrome are presented. The evoking medicaments were penicillin and thioacetazone. The two patients showed a severe course with an extensive affection of the body surface. The therapy with glucocorticosteroids, electrolyte substitution and local treatment of the skin lesions was successful in the two cases.
mesh_terms: D000328:Adult; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000009:adverse effects; D013262:Stevens-Johnson Syndrome / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D013828:Thioacetazone / Q000009:adverse effects
chemical_list: D005938:Glucocorticoids; D010406:Penicillins; D013828:Thioacetazone
vernacular_title: Ein kasuistischer Beitrag zum Lyell-Syndrom.