title: [Comparative immunochemical and physicochemical study of the neurospecific antigen 10-40-4 from human and rat brains].
abstract: Immunological non-identity of neurospecific protein 10-40-4 from various mammalian species has been demonstrated. Significant immunochemical differences were found between the protein 10-40-4 from the brain of rat, guinea pig and man. With respect to their physicochemical properties, no significant differences were found between individual neurospecific proteins 10-40-4 from the brain of man and rat. Therefore, immunological differences in the structure of a neurospecific determinant together with identical physicochemical properties of the proteins investigated imply that the latter are presented by species variations of the same protein.
mesh_terms: D000818:Animals; D000941:Antigens / Q000032:analysis* / Q000302:isolation & purification; D001921:Brain / Q000276:immunology*; D002417:Cattle; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002522:Chlorocebus aethiops; D004285:Dogs; D000939:Epitopes / Q000032:analysis* / Q000302:isolation & purification; D006168:Guinea Pigs; D006801:Humans; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000302:isolation & purification; D009928:Organ Specificity; D011817:Rabbits; D051381:Rats; D013045:Species Specificity
chemical_list: D000941:Antigens; D000939:Epitopes; D009419:Nerve Tissue Proteins
vernacular_title: Sravnitel'noe immunokhimicheskoe i fiziko-khimicheskoe izuchenie neĭrospetsificheskogo antigena 10-40-4 iz mozga cheloveka i krysy.