title: Morphofunctional anatomy of disseminated endocrine cells related to the regulation of precapillary vessels.
abstract: It is presumed that the contractile tone of precapillary blood vessels is regulated by various mechanisms. Disseminated endocrine cells are sites of production of vasoactive peptides, which are partly involved in the regulation of the local or systemic circulation. The peptide hormones may exert a direct effect on smooth-muscle cells, but the action may also be mediated by the stimulation of perivascular mast cells, perivascular nerves, or endothelial cells. Among these vasoactive peptides, attention is focused on neurotensin, substance P, and vasoactive intestinal polypeptide.
mesh_terms: D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology; D004702:Endocrine Glands / Q000166:cytology*; D006801:Humans; D008833:Microcirculation / Q000166:cytology / Q000502:physiology*; D009490:Neurosecretory Systems / Q000166:cytology*; D009496:Neurotensin / Q000502:physiology; D013373:Substance P / Q000502:physiology; D014660:Vasoactive Intestinal Peptide / Q000502:physiology
chemical_list: D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D009496:Neurotensin