Release of rRNA from liver nuclei during the early stages of the acute-phase reaction.
Liver nuclei isolated from rats 5 h after turpentine injection show an increased release of rRNA, of the transport-related nucleoside-triphosphatase activity and of the amount of nuclear RNA; RNA methylation is also likely to undergo some activation. These changes occur when RNA synthesis is still normal.
D000208:Acute Disease; D000209:Acute-Phase Proteins; D000818:Animals; D001798:Blood Proteins / Q000235:genetics; D002467:Cell Nucleus / Q000378:metabolism; D007249:Inflammation / Q000235:genetics*; D008099:Liver / Q000378:metabolism*; D008745:Methylation; D012335:RNA, Ribosomal / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D014425:Turpentine
D000209:Acute-Phase Proteins; D001798:Blood Proteins; D012335:RNA, Ribosomal; D014425:Turpentine