Serum PAPP-A in normal pregnancy: relationship to fetal and maternal characteristics.
Pregnancy associated plasma protein A (PAPP-A) was measured in maternal serum by electroimmunoassay in 414 women (with subsequent normal pregnancy outcome) during the 38th week of pregnancy. PAPP-A levels were examined in relation to maternal and fetal characteristics, revealing a statistically significant relationship with maternal weight, placental weight, fetal sex and gravidity. The correlation of PAPP-A levels to fetal sex and gravidity could not be explained by differences in placental or maternal weight. Mean levels of PAPP-A were also not significantly different in relation to fetal sex.
D001723:Birth Rate; D001835:Body Weight; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D011263:Pregnancy Trimester, Third; D011266:Pregnancy-Associated Plasma Protein-A / Q000032:analysis*; D012732:Sex Determination Analysis; D012737:Sex Factors
D011257:Pregnancy Proteins; D011266:Pregnancy-Associated Plasma Protein-A