An animal model for the study of the function of pregnancy-specific beta 1-glycoprotein and pregnancy zone protein: a review.
Two pregnancy-associated murine proteins, PAMP-1 and PAMP-2, have been found to be immunologically cross-reacting analogues to the human proteins pregnancy zone protein (PZP) and pregnancy-specific beta 1-glycoprotein (SP-1), respectively. In this study, the physiochemical and biological properties of the proteins are compared and the effect on pregnancy of administration of monospecific antibodies against the proteins is reported.
D000028:Abortion, Induced; D000818:Animals; D000906:Antibodies / Q000008:administration & dosage; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005260:Female; D006801:Humans; D008297:Male; D008431:Maternal-Fetal Exchange; D051379:Mice; D008954:Models, Biological; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis / Q000502:physiology*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis / Q000276:immunology / Q000502:physiology*
D000906:Antibodies; D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins