title: New trends in diabetes research: the search for an etiologically oriented treatment for type I diabetes mellitus.
abstract: The possibility of preventive intervention in Type I or insulin-dependent diabetes mellitus (IDDM) during periods of latency and partial remission of the disease has stimulated the search for agents that interfere with the genesis of IDDM by acting on its etiology and/or by protecting the beta cell against different aggressions. Recent attempts, which have been applied mostly to animal models, but also to patients, include: antiviral therapy, immunotherapy, administration of free radical scavengers, nicotinamide and high protein diet.
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000517:prevention & control / Q000628:therapy*; D003927:Diet, Diabetic; D004195:Disease Models, Animal; D006801:Humans; D007167:Immunotherapy; D007372:Interferons / Q000627:therapeutic use; D009536:Niacinamide / Q000627:therapeutic use; D013482:Superoxide Dismutase / Q000627:therapeutic use
chemical_list: D009536:Niacinamide; D007372:Interferons; D013482:Superoxide Dismutase