title: Monitoring of T lymphocytes before and after surgical removal of hepatic tumors.
abstract: Monitoring of peripheral T lymphocyte level after surgical removal of hepatic tumors has been periodically carried out in thirty patients to observe the relation between T lymphocytes suppression and presence of tumor. Rosette formation with neuraminidase treated sheep erythrocytes has been considered as T lymphocytes. Twenty-two cases were considered as free from residual hepatic tumor after operation and eight cases were diagnosed as residual or recurrent hepatic tumor postoperatively. The result indicated that significant difference in T lymphocyte level has been observed between preoperative level (59.3 +/- 14.0%) and postoperative 4th week level (69.4 +/- 5.5%) 5th week level (69.5 +/- 8.3%) (both p less than 0.01) in group of complete removal of hepatic tumor. While in group of residual or recurrent hepatic tumor, the average T lymphocytes stayed at rather low level throughout the postoperative course. From another point of view, when we compare the T lymphocyte level between the two groups, significant difference has been observed either at postoperative 4th week (69.4 +/- 5.5% vs 57.8 +/- 12.7%) or at postoperative 5th week (69.5 +/- 8.3% vs 53.8 +/- 11.6%) (both p less than 0.01). Accordingly we believed that there is a close relation between depressed T lymphocyte level and presence of hepatic tumor.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008113:Liver Neoplasms / Q000097:blood* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D013601:T-Lymphocytes; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins