The spinal monoaminergic systems relating to ejaculation. II. Ejaculation and serotonin.
The effects of Ro 4-4602 and L-5-hydroxytryptophan on manually induced ejaculation in dogs and on spinal monoamines in dogs were investigated. From the results obtained in the study it was concluded that the serotonergic system in the spinal cord is an intermediate mechanism which inhibits the occurrence of ejaculation. Both the results in this study and the results in our previous paper seem to indicate that ejaculation occurs with the reconciliation of the spinal dopaminergic and serotonergic system.
D000818:Animals; D001545:Benserazide / Q000494:pharmacology; D004285:Dogs; D004298:Dopamine / Q000032:analysis; D004542:Ejaculation / Q000187:drug effects*; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D012701:Serotonin / Q000494:pharmacology*; D013116:Spinal Cord / Q000032:analysis*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D001545:Benserazide; D004298:Dopamine; D009638:Norepinephrine