title: Transitional cell carcinoma of the nasal passages: dramatic response to chemotherapy.
abstract: Transitional cell carcinoma of the nasal passages and sinuses is an uncommon tumor of the head and neck, for which the efficacy of chemotherapy has not been previously reported. A dramatic and complete tumor response to chemotherapy with cis-platinum, methotrexate, and bleomycin is described in a patient with advanced proptosis due to extensive local recurrence of transitional cell carcinoma. Relevant literature on this rare histologic type of head and neck cancer has been reviewed.
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D005094:Exophthalmos / Q000209:etiology; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000188:drug therapy*; D008727:Methotrexate / Q000008:administration & dosage; D009669:Nose Neoplasms / Q000188:drug therapy*; D010255:Paranasal Sinus Neoplasms / Q000188:drug therapy*
chemical_list: D001761:Bleomycin; D002945:Cisplatin; D008727:Methotrexate