[A method for the cryopreservation of thrombocytes].
By using dimethylsulfoxide (0.7 mol/l) a technique of cryoconservation of thrombocyte concentrates was elaborated, with own material-technological possibilities being taken into consideration. In comparison to fresh thrombocytes the results of parameters tested in vitro reveal a mean functional ability of 50%. The survival time of cells stored in this way in vivo may be compared with fresh cells. On this basis HLA-typed single-donor pools could be established for clinical application.
D001792:Blood Platelets / Q000187:drug effects*; D001793:Blood Preservation / Q000379:methods*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology*; D005615:Freezing; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count / Q000187:drug effects
D004121:Dimethyl Sulfoxide
Eine Methode zur Kryokonservierung von Thrombozyten.