Release of beta-thromboglobulin during the preparation, in vitro storage and cryopreservation of platelet concentrates.
Beta-thromboglobulin is a platelet specific protein which is released from platelets during the platelet release reaction. The amount of beta-thromboglobulin released during various conditions of in vitro storage, including cryopreservation, was compared. The results suggest the measurement of beta-thromboglobulin is unlikely to be of use as a quality control assay for monitoring the in vitro viability of stored platelets.
D001609:Beta-Globulins / Q000378:metabolism*; D001792:Blood Platelets / Q000378:metabolism*; D001793:Blood Preservation; D003451:Cryoprotective Agents / Q000494:pharmacology; D005615:Freezing; D006801:Humans; D011786:Quality Control; D013696:Temperature; D001620:beta-Thromboglobulin / Q000378:metabolism*
D001609:Beta-Globulins; D003451:Cryoprotective Agents; D001620:beta-Thromboglobulin