[Effect of rearing conditions on nucleic acid synthesis in the brain of rats of different genotypes].
The incorporation of [3H]thymidine into DNA and of [14C]uridine into RNA has been investigated in different areas of brain and in liver of inbred August rats, non-inbred Wistar rats and hybrids between male wild-type and female Wistar rats which were kept either under normal conditions or under intensive sensory stimulation at different age. DNA metabolism has been found to display tissue, regional, age-dependent and interlinear differences. Sensory stimulation influences considerably the synthesis of nucleic acids which is maximal at early ontogenesis stages and in the brain of hybrid animals.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis*; D004777:Environment; D005260:Female; D005838:Genotype; D006579:Heterozygote; D008099:Liver / Q000378:metabolism; D008297:Male; D010812:Physical Stimulation / Q000379:methods; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains / Q000378:metabolism*
D012313:RNA; D004247:DNA
Vliianie usloviĭ vospitaniia na sintez nukleinovykh kislot v mozgu krys s razlichnym genotipom.