title: The nucleotide sequence of the Akv murine leukemia virus genome.
abstract: The nucleotide sequence of an infectious molecular clone of the Akv murine leukemia virus has been determined by the dideoxy chain termination method after subcloning in bacteriophage M13 vectors. The sequence predicts an RNA genome of 8371 nucleotides containing three large open reading frames corresponding to the gag, pol, and env genes. Signal sequences for transcription, splicing, and translation have been identified. The positions of 95 major RNase T1 resistant oligonucleotides of the Akv RNA genome have been located.
mesh_terms: D000406:AKR murine leukemia virus / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D005814:Genes, Viral; D009052:Leukemia Virus, Murine / Q000235:genetics*; D009843:Oligoribonucleotides / Q000032:analysis; D011061:Poly A / Q000032:analysis; D014176:Protein Biosynthesis; D012313:RNA / Q000032:analysis; D012315:RNA Caps / Q000032:analysis; D012333:RNA, Messenger; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D006163:Ribonuclease T1 / Q000378:metabolism; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics
chemical_list: D009843:Oligoribonucleotides; D012315:RNA Caps; D012333:RNA, Messenger; D012367:RNA, Viral; D014764:Viral Proteins; D011061:Poly A; D012313:RNA; D004262:DNA Restriction Enzymes; D006163:Ribonuclease T1