[Simultaneous studies of granulocyte phagocytosis, serum immunoglobulins, acute phase proteins and the 3d complement component in patients with malignant tumors].
In a clinical study granulocyte phagocytosis, serum levels of IgG and IgA and of the acute phase proteins ceruloplasmin, alpha-1-antitrypsin, transferrin, and of the 3rd component of complement (C3) are simultaneously determined in tumor patients and compared with healthy probands of the same age and with patients being under general surgical treatment. There was found a negative correlation between granulocyte phagocytosis and the IgG level and a positive correlation between phagocytosis and the C3 level in each group. Despite of some significant differences between all groups of probands with respect to the measured parameters no new essential information for clinical use could be received, thus the determination of granulocyte phagocytosis remains the only recommended method.
D000209:Acute-Phase Proteins; D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000032:analysis*; D002570:Ceruloplasmin / Q000032:analysis; D003176:Complement C3 / Q000032:analysis*; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology*; D010587:Phagocytosis; D011471:Prostatic Neoplasms / Q000276:immunology; D012004:Rectal Neoplasms / Q000276:immunology; D013274:Stomach Neoplasms / Q000276:immunology; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
D000209:Acute-Phase Proteins; D001798:Blood Proteins; D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D002570:Ceruloplasmin
Simultane Untersuchungen der Granulozytenphagozytose, Serumimmunglobuline, akute-Phase-Proteine und der dritten Komplementkomponente bei Patienten mit malignen Tumoren.