title: The prognostic significance of acute phase proteins in patients with inoperable squamous cell carcinoma of the bronchus.
abstract: In 95 patients with inoperable squamous cell carcinoma of the bronchus, nine potential serum "markers" were analysed for their prognostic significance. Lactate dehydrogenase, alpha 1 HS-glycoprotein, ferritin, carcino-embryonic antigen and immunoglobulin E did not prove to be useful as prognostic indices. The erythrocyte sedimentation rate and the acute phase proteins alpha 1 acid glycoprotein, C-reactive protein and prealbumin were correlated with survival. After taking the performance status and tumour stage into account, C-reactive protein still proved to be a strong prognosticator. The clinical relevance of the acute phase proteins signifying a so-called "biochemical status" next to the "clinical status" is discussed.
mesh_terms: D000209:Acute-Phase Proteins; D000368:Aged; D001798:Blood Proteins / Q000032:analysis*; D001799:Blood Sedimentation; D001984:Bronchial Neoplasms / Q000097:blood*; D002097:C-Reactive Protein / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009961:Orosomucoid / Q000032:analysis; D011379:Prognosis; D012306:Risk
chemical_list: D000209:Acute-Phase Proteins; D001798:Blood Proteins; D009961:Orosomucoid; D002097:C-Reactive Protein