title: Regulation of pacing rate by variations of mixed venous oxygen saturation.
abstract: Right ventricular oxygen saturation (SO2) may be an ideal sensor for determining the rate of an implanted pacemaker. In order to prove this hypothesis, the obtained signals were optimally analyzed; determinations of SO2 at rest and during exercise were made in healthy volunteers and in patients with pacemakers; and an algorithm was developed for varying pacing rate as a function of measured SO2. The results suggest that this method may be applicable to the long-term implantee.
mesh_terms: D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D001831:Body Temperature; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004567:Electrodes, Implanted; D006321:Heart / Q000502:physiology*; D006327:Heart Block / Q000503:physiopathology; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D010100:Oxygen / Q000097:blood*; D010138:Pacemaker, Artificial; D012804:Sick Sinus Syndrome / Q000503:physiopathology; D016276:Ventricular Function
chemical_list: D010100:Oxygen