Immunoreactive alpha 2-macroglobulin in rheumatoid synovial membrane.
alpha 2-Macroglobulin was demonstrated immunohistochemically in macrophage-like cells of rheumatoid arthritic synovial tissue. It is concluded that these intracellular deposits probably represent phagocytosed protease-alpha 2-macroglobulin complexes. A contributing local production of alpha 2-macroglobulin is, however, not excluded by the present findings.
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D013583:Synovial Membrane / Q000276:immunology* / Q000473:pathology; D000511:alpha-Macroglobulins / Q000276:immunology*
D000511:alpha-Macroglobulins