Expression of the prolactin gene in human decidua-chorion.
Messenger RNA (mRNA) purified from human decidua-chorion hybridizes with a 32P-cDNA probe for human prolactin. In contrast, mRNA from human trophoblast and amnion does not hybridize to prolactin cDNA. The migration position on agarose gels of prolactin-specific mRNA from human decidua-chorion is similar to that for mRNA from ovine pituitary, suggesting a similar sized mRNA coding for prolactin in these different tissues and species. These data demonstrate unambiguously that the prolactin gene is expressed in human decidua-chorion, confirming previous immunochemical reports of prolactin production by this tissue in culture.
D000650:Amnion / Q000378:metabolism; D000818:Animals; D002823:Chorion / Q000378:metabolism*; D004247:DNA / Q000032:analysis; D003656:Decidua / Q000378:metabolism*; D005260:Female; D005796:Genes; D006801:Humans; D010902:Pituitary Gland / Q000378:metabolism; D011061:Poly A / Q000235:genetics; D011247:Pregnancy; D011388:Prolactin / Q000235:genetics*; D012313:RNA / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012756:Sheep
D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D011388:Prolactin; D004247:DNA