Subcutaneous pseudosarcomatous polyvinylpyrrolidone granuloma.
A 77-year-old man developed an induration of the buttock following repeated injections of an antihypertensive remedy containing polyvinylpyrrolidone (PVP). The excised tumor had a cellular, pseudosarcomatous appearance with abundant extracellular material, and resembled a myxoid liposarcoma. All of the staining reactions and infra-red spectrophotometry of the deposition indicated the presence of PVP. The awareness of such a cellular PVP granuloma is important for surgical pathologists so as to avoid the diagnosis of sarcoma.
D000368:Aged; D002081:Buttocks; D003937:Diagnosis, Differential; D006099:Granuloma / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007279:Injections, Subcutaneous; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D011205:Povidone / Q000008:administration & dosage / Q000009:adverse effects* / Q000032:analysis; D013055:Spectrophotometry, Infrared; D013194:Staining and Labeling
D011205:Povidone