Oncofetal antigens in ovarian cyst fluids.
The levels of five oncofetal antigens were measured in ovarian cyst fluids. Significantly raised levels of carcinoembryonic antigen (CEA), human chorionic gonadotropin, beta 2-microglobulin, and alpha-fetoprotein were found in ovarian cyst samples. Human placental lactogen was not detectable in any samples. Mucinous cyst fluids demonstrated higher levels of CEA than serous fluids in both malignant and benign conditions. We could not distinguish between malignant and benign conditions with any of the markers. Except for CEA, there is no difference in values between mucinous and serous cystadenocarcinomas.
D000951:Antigens, Neoplasm / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D006801:Humans; D010048:Ovarian Cysts / Q000378:metabolism* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000032:analysis* / Q000473:pathology; D010446:Peptide Fragments / Q000032:analysis*; D010928:Placental Lactogen / Q000032:analysis*; D000509:alpha-Fetoproteins / Q000032:analysis*; D001613:beta 2-Microglobulin / Q000032:analysis*
D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D000509:alpha-Fetoproteins; D001613:beta 2-Microglobulin; D010928:Placental Lactogen