title: [Biosynthesis of DNA and RNA in the liver under conditions of deficient nutrition and exposure to N-nitrosopiperidine].
abstract: Effect of N-nitrosopiperidine on macromolecules was studied. Nutrition deficient in retinol, tocopherol, ascorbic acid and essential amino acids was shown to increase the inhibitory action of N-nitrosopiperidine on synthesis of DNA and RNA liver tissue.
mesh_terms: D000601:Amino Acids, Essential / Q000172:deficiency*; D000818:Animals; D001206:Ascorbic Acid Deficiency / Q000378:metabolism; D001361:Avitaminosis / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008239:Lysine / Q000172:deficiency; D008297:Male; D008715:Methionine / Q000172:deficiency; D009602:Nitrosamines / Q000633:toxicity*; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D013912:Threonine / Q000172:deficiency; D014802:Vitamin A Deficiency / Q000378:metabolism; D014811:Vitamin E Deficiency / Q000378:metabolism
chemical_list: D000601:Amino Acids, Essential; D009602:Nitrosamines; D013912:Threonine; D012313:RNA; C002743:N-nitrosopiperidine; D004247:DNA; D008715:Methionine; D008239:Lysine
vernacular_title: Biosintez DNK i RNK pecheni v usloviiakh nepolnotsennogo pitaniia i vozdeĭstviia N-nitrozopiperidina.