title: Initial results with an activated pyrolytic carbon tip electrode.
abstract: The initial results acquired from testing of a new activated pyrocarbon electrode for cardiac pacing are presented. In vitro testing has shown energy efficiency to be higher than for platinum electrodes. Histologic examination of implanted leads in animals has demonstrated a less significant tissue reaction at the tip. Finally, in a clinical trial of 121 patients with these leads, strength-duration curves have low rheobase values. Chronic thresholds are often consistently low. These reports suggest very satisfactory results with this pyrolytic carbon electrode.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects / Q000627:therapeutic use*; D002244:Carbon / Q000009:adverse effects / Q000627:therapeutic use*; D004285:Dogs; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004699:Endocardium / Q000473:pathology; D006801:Humans; D010138:Pacemaker, Artificial; D010984:Platinum / Q000009:adverse effects / Q000627:therapeutic use; D012756:Sheep; D012965:Sodium Chloride / Q000627:therapeutic use
chemical_list: D001672:Biocompatible Materials; C009139:pyrolytic carbon; D012965:Sodium Chloride; D010984:Platinum; D002244:Carbon