A model of an intraprostatic vas deferens in the rat.
The study of the effect of hormones in seminal fluid upon prostate tissue is hampered by the lack of a suitable model. Such a model is described in this paper, and its possible usefulness is discussed. The vas deferens of the rat is moved from its normal position into a surgical incision into the ventral prostate. Squamous metaplasia of epithelium in prostatic acini at early stages is replaced by cuboidal epithelium. At later stages, normal-appearing glandular epithelium is seen as close as 50 micrometers to the vas deferens. The structure of the vas deferens is not affected.
D000818:Animals; D004848:Epithelium / Q000473:pathology; D008297:Male; D008679:Metaplasia; D008954:Models, Biological; D011467:Prostate / Q000473:pathology / Q000502:physiology*; D011470:Prostatic Hyperplasia; D051381:Rats; D011919:Rats, Inbred Strains; D014649:Vas Deferens / Q000473:pathology / Q000637:transplantation*