title: Middle ear effusion in children: a report of treatment in 500 cases.
abstract: Records were studied of 500 children younger than 9 years of age with middle ear effusion who had received one of three treatment strategies: (1) administration of medication, including decongestants, antihistamines or antibiotics (or a combination), (2) administration of medication for a limited time and then surgical therapy if effusion did not resolve or (3) myringotomy done immediately with insertion of ventilation tubes and, in some cases, removal of adenoids. Early surgical intervention resulted in significantly shorter delay in hearing restoration. It did not result in a lower recurrence rate and it did not reduce the number of occasions when thick fluid, as compared with thin fluid, was found at operation. Four children for whom medical and surgical treatment failed were considered candidates for mild gain, low maximum-power-output hearing aids. All other children had normal hearing after treatment. Medication was successful in achieving this goal in 48 percent of the cases.
mesh_terms: D002648:Child; D004338:Drug Combinations / Q000627:therapeutic use; D004809:Ephedrine / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008876:Middle Ear Ventilation; D014663:Nasal Decongestants / Q000627:therapeutic use; D010033:Otitis Media / Q000628:therapy*; D054199:Pseudoephedrine; D014311:Triprolidine / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; D006634:Histamine H1 Antagonists; D014663:Nasal Decongestants; C006399:pseudoephedrine, triprolidine drug combination; D014311:Triprolidine; D004917:Erythromycin; D054199:Pseudoephedrine; D004809:Ephedrine