Production of lymphokines by murine cortisone-resistant thymocytes, stimulated by concanavalin A. II. Kinetics of interleukin-2 and interferon production in vitro.
The results presented in this study indicate that cortisone-resistant thymocytes stimulated with concanavalin A produce interferon and interleukin-2. The kinetic studies show that the peak of interleukin-2 activity precedes the maximal level of interferon activity which occurs later and does not show as rapid decline as the activity of interleukin-2.
D000818:Animals; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006854:Hydrocortisone / Q000008:administration & dosage; D007372:Interferons / Q000096:biosynthesis*; D007376:Interleukin-2 / Q000096:biosynthesis*; D007700:Kinetics; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000145:classification / Q000187:drug effects* / Q000276:immunology
D007376:Interleukin-2; D003208:Concanavalin A; D007372:Interferons; D006854:Hydrocortisone