Interferon treatment inhibits pinocytosis.
Treating mouse L cells with crude or purified mouse interferon inhibited fluid-phase pinocytosis. Inhibition was maximum at 24 h after treatment with 1,000 U of interferon per ml and was dose dependent and reversible with time. Pinocytosis was inhibited when human and chicken embryo cells were treated with homologous, but not heterologous, interferons.
D000818:Animals; D002645:Chickens; D006735:Horseradish Peroxidase; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007739:L Cells; D051379:Mice; D010873:Pinocytosis / Q000187:drug effects*; D013045:Species Specificity
D007372:Interferons; D006735:Horseradish Peroxidase