[Metabolic transformation affected by specific Salmonella O antigen in the lymphocytes of salmonellosis patients].
Metabolic transformation in the lymphocytes of salmonellosis patients, manifested by changes in the proportion of nucleic acids due to the stimulating action of Salmonella specific O antigen, was studied by the method of microspectral luminescent analysis. The level of single-helix nucleic acids in lymphocytes was shown to increase 6-8 hours after the stimulating action of specific O antigen, which was manifested by the increase of the alpha parameter from 0.21 to 0.68 in salmonellosis patients. This made it possible to confirm the diagnosis of salmonellosis in 92-95% of cases even at the early period of the disease when serodiagnosis could not yet be made.
D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology*; D005759:Gastroenteritis / Q000097:blood; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism*; D009696:Nucleic Acids / Q000097:blood; D019081:O Antigens; D012475:Salmonella / Q000276:immunology*; D012480:Salmonella Infections / Q000097:blood*; D012764:Shigella sonnei / Q000276:immunology; D013050:Spectrometry, Fluorescence; D013997:Time Factors
D000942:Antigens, Bacterial; D009696:Nucleic Acids; D019081:O Antigens
Metabolicheskaia perestroĭka pod vozdeĭstviem spetsificheskogo O-antigena sal'monell v limfotsitakh bol'nykh sal'monellezom.