title: [Effects of lindane, an organochlorine insecticide, on the thyroid gland of larvae of Xenopus laevis Daudin in premetamorphosis].
abstract: The effects of 0.5 ppm of lindane were studied on the morphogenesis and the initial functioning of the thyroid gland. Some disturbances were observed: the formation of the first follicles were delayed and ultrastructural changes were noted: increase in the number of mitochondria, reduction of the endoplasmic reticulum. This demonstrates a noxious effect of lindane at the beginning of the functional maturation of the thyroid gland.
mesh_terms: D000818:Animals; D001556:Hexachlorocyclohexane / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D009024:Morphogenesis / Q000187:drug effects; D013961:Thyroid Gland / Q000187:drug effects* / Q000503:physiopathology / Q000648:ultrastructure; D014982:Xenopus laevis
chemical_list: D001556:Hexachlorocyclohexane
vernacular_title: Effets du lindane, insecticide organochloré, sur la thyroïde des larves de Xenopus laevis Daudin en prémétamorphose.