[Voltammetric detection of extracellular 5-hydroxyindole compounds at the level of cell bodies and the terminals of the raphe system: variations during the wake-sleep cycle in the rat in chronic experiments].
In rats, chronically implanted for measurements of both voltammetric and polygraphic parameters, variations of the electrochemical signal corresponding to extracellular 5-hydroxyindole compounds (peak 3) were measured during the sleep-waking cycle. The higher amplitude of this signal is always measured during waking. It decreases during slow-wave sleep (20 to 30%) and reaches its lower value during paradoxical sleep (30 to 40%). This phenomenon has been found in all structures investigated, cerebral cortex, caudate nuclei, dorsal hippocampus, suprachiasmatic nuclei, cerebellum, nuclei raphe dorsalis, centralis, pontis and magnus.
D000818:Animals; D001921:Brain / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology*; D004553:Electric Conductivity; D006897:Hydroxyindoleacetic Acid / Q000032:analysis*; D007700:Kinetics; D008297:Male; D008839:Microelectrodes; D009928:Organ Specificity; D011903:Raphe Nuclei / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000032:analysis*; D012890:Sleep / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid
Détection voltamétrique des composés 5-hydroxyindols extracellulaires au niveau des corps cellulaires et des terminaisons du système du raphé: variations pendant le cycle veille-sommeil chez le Rat en expérimentation chronique.