title: Stain intensity of human nucleolus organizer region reflects incorporation of uridine into mature ribosomal RNA.
abstract: The stain intensity of the nucleolus organizer regions (NORs) of acrocentric chromosomes was correlated positively with incorporation of [3H]uridine into 18S rRNA and 28S rRNA from cultured diploid human skin fibroblasts. An analysis of these data from twins by a path model indicated that no other common genetic or environmental parameters were required to explain the relationship between NOR scores and uptake of [3H]uridine into mature rRNA species.
mesh_terms: D000293:Adolescent; D000328:Adult; D002478:Cells, Cultured; D002648:Child; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008875:Middle Aged; D009697:Nucleolus Organizer Region; D011247:Pregnancy; D012335:RNA, Ribosomal / Q000378:metabolism*; D013194:Staining and Labeling; D014430:Twins, Monozygotic; D014529:Uridine / Q000378:metabolism*
chemical_list: D012335:RNA, Ribosomal; D014529:Uridine