Pemphigus foliaceus in a haemophilic child: cytomegalovirus induction?
A 3 1/2-year-old haemophilic child, repeatedly transfused with blood products, developed pemphigus foliaceus with presence in serum of both intercellular and anti-cytomegalovirus antibodies at high titre. The locus A26, which seems to be a genetic marker of pemphigus, was detected in his haplotype. Cytomegalovirus infection of transfusional origin is suspected to have triggered the outbreak of pemphigus.
D002675:Child, Preschool; D003586:Cytomegalovirus Infections / Q000209:etiology*; D006680:HLA Antigens / Q000032:analysis; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans; D008297:Male; D010392:Pemphigus / Q000209:etiology* / Q000276:immunology; D065227:Transfusion Reaction
D006680:HLA Antigens