title: Impairment of some microphage functions in recurrent herpes simplex.
abstract: Chemotactic, phagocytic and intracellular killing activities of polymorphonuclear leukocytes (PMNL) were investigated in vitro in 49 patients suffering from recurrent bouts of herpes simplex. A slight impairment of chemotactic activity and a markedly reduced capacity of killing Candida albicans blastospores were revealed. Phagocytic capacity and NADH-dependent oxidase activity of PMNL proved to be normal. The results point to an alteration of some PMNL functions in these patients.
mesh_terms: D000328:Adult; D002176:Candida albicans / Q000254:growth & development; D002634:Chemotaxis, Leukocyte; D005260:Female; D006558:Herpes Genitalis / Q000276:immunology*; D006560:Herpes Labialis / Q000276:immunology*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D009504:Neutrophils / Q000502:physiology*; D012008:Recurrence