'Cardiac' enzymes after transurethral resection of the prostate.
Postoperative serial determinations of serum total creatine kinase (CK) and the CK-B subunit (by immunoinhibition), and of total lactate dehydrogenase (LD) and isoenzyme LD-1 (by immunoprecipitation), were performed in 16 and 9 patients, respectively, after uncomplicated transurethral resection of the prostate (TURP). Total CK remained unchanged. An early, modest increase in serum CK-B activity, accompanied by an unusually high CK-B/total CK relation, correlated significantly with duration of operation and amount of tissue resected. A slight, early elevation of the total LD level was not accompanied by an increase in LD-1. If the possibility of small increases in CK-B and LD from the prostate is taken into consideration, routine criteria for diagnosing myocardial damage may be applied after TURP.
D000368:Aged; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D009203:Myocardial Infarction / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology*; D011184:Postoperative Period; D011470:Prostatic Hyperplasia / Q000201:enzymology / Q000601:surgery*; D014521:Urethra
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase