title: Pacing threshold interval with decreasing and increasing output.
abstract: The study was made in 44 patients, of which 23 received a new endocardial electrode and 21 were investigated during pulse-generator replacement. Indication for pacemaker therapy was sino-atrial bradycardia in 12 patients and atrio-ventricular block in 32 patients. When the pacing threshold was determined with decreasing output it was found to be 0.6V/0.7 mA for new implantations and 2.0 V/2.0 mA with pulse generator replacement. When determined with increasing output the threshold was found to be an average 0.20 V/0.20 mA higher than when determined with decreasing output (threshold interval). The maximal difference observed was 0.70 V/0.55 mA. This threshold interval was of the same size irrespective of pacemaker indication and spontaneous activity and whether the electrode was newly implanted or not. Pacemaker ventricular block of Mobitz type I with Wenckebach periodicity was never observed.
mesh_terms: D001919:Bradycardia / Q000628:therapy*; D004562:Electrocardiography; D006327:Heart Block / Q000628:therapy*; D006339:Heart Rate; D006801:Humans; D010138:Pacemaker, Artificial