title: Angiogenesis inhibitors and their delivery systems.
abstract: The extensive vascularity of solid tumors has been recognized for over 100 yr (1). However, only in the past 15 yr has the importance of this phenomenon been appreciated and only in the past 6 yr has the possibility of chemical interference been apparent. In this article, we review the emerging field of tumor vascularization inhibitors.
mesh_terms: D020533:Angiogenesis Inhibitors; D000818:Animals; D001681:Biological Assay; D002356:Cartilage / Q000502:physiology; D003315:Cornea / Q000098:blood supply; D003316:Corneal Diseases / Q000503:physiopathology; D005134:Eye Neoplasms / Q000098:blood supply; D006801:Humans; D008545:Melanoma / Q000503:physiopathology; D051379:Mice; D008970:Molecular Weight; D009369:Neoplasms / Q000098:blood supply*; D009389:Neovascularization, Pathologic / Q000188:drug therapy; D011506:Proteins / Q000302:isolation & purification / Q000502:physiology* / Q000633:toxicity; D011817:Rabbits
chemical_list: D020533:Angiogenesis Inhibitors; D011506:Proteins