A histochemical and immunohistological study of a testicular malignant teratoma containing embryonic and extraembryonic elements in various stages of development.
A testicular malignant teratoma containing embryoid bodies and other embryonic and extra-embryonic structures in various stages of development has been examined by several histochemical and immunohistological techniques to study the distribution of various substances in the teratomatous elements. The substances demonstrated included various types of mucins; argyrophil, argentaffin, Paneth cells and haemosiderin granules; alpha-fetoprotein, alpha-l-anti-trypsin, lysozyme, beta-HCG and CEA. The significance of the findings is discussed in relation to early embryonic development.
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000032:analysis; D018997:Chorionic Gonadotropin, beta Subunit, Human; D006651:Histocytochemistry; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D009077:Mucins / Q000032:analysis; D009113:Muramidase / Q000032:analysis; D010446:Peptide Fragments / Q000032:analysis; D013724:Teratoma / Q000196:embryology* / Q000276:immunology / Q000473:pathology; D013736:Testicular Neoplasms / Q000196:embryology* / Q000276:immunology / Q000473:pathology; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis
D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D009077:Mucins; D010446:Peptide Fragments; D000515:alpha 1-Antitrypsin; D000509:alpha-Fetoproteins; D009113:Muramidase