Involvement of Y chromosomal loci in the synthesis of Drosophila hydei sperm proteins.
A comparative study of the protein patterns in testes of wild-type and X/O flies of Drosophila hydei revealed quantitative differences in at least three major protein fractions. One protein component of a Mr 155,000 fraction and a protein of Mr 35,000 are completely absent in X/O testes. The amount of protein in a Mr 55,000 fraction is considerably reduced. The tubulins, which are part of this fraction, are also reduced in amount. All three proteins were found as constituents of sperm tails. Studies of Y chromosomal mutants revealed that the presence of at least two of these proteins depends on the activity of loci O, P, and Q of the Y chromosome. However, preliminary evidence indicates an autosomal location of the genes of these sperm proteins. This suggests a regulatory role of Y chromosomal genes in the production of some major sperm proteins.
D000818:Animals; D004330:Drosophila / Q000235:genetics*; D000939:Epitopes / Q000276:immunology; D008297:Male; D009154:Mutation; D014176:Protein Biosynthesis; D011506:Proteins / Q000276:immunology; D013094:Spermatozoa / Q000378:metabolism*; D013737:Testis / Q000378:metabolism; D014404:Tubulin / Q000096:biosynthesis; D014998:Y Chromosome
D000939:Epitopes; D011506:Proteins; D014404:Tubulin