[Arterial hypertension induced by an excess of mineralocorticoids caused by abuse of nasal spray. Report of a case].
Among the various syndromes caused by excess mineralocorticoids, the factitious syndrome produced by excessive 9-alpha-fluorprednisolone inhalations is more common than might be expected, especially in places where the drug is easily obtained without a doctor's prescription. A fairly typical case of addiction to a nasal spray containing ephedrine hydrochloride and an imidazoline compound as well as the steroid is described. The diagnosis of the case is analysed with details of certain differences from similar cases reported in the literature and the modifications to clinical and instrumental parameters achieved after over two months' treatment with spironolactone are described.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D005260:Female; D005477:Fluprednisolone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D014663:Nasal Decongestants / Q000009:adverse effects
D014663:Nasal Decongestants; C065592:isoflupredone acetate; D005477:Fluprednisolone
Ipertensione arteriosa da eccesso di mineralcorticoidi dovuta ad abuso di spray nasale. Descrizione di un caso.