Bleomycin-induced Raynaud's phenomenon and acral sclerosis.
This study presents a case of two of the more uncommon side effects of bleomycin therapy for a metastasized testicular carcinoma: Raynaud's phenomenon and acral sclerosis. It is suggested that this association indicates a common pathogenic mechanism. These side effects may serve as an experimental model in the study of Raynaud's phenomenon and acral sclerosis.
D000328:Adult; D001761:Bleomycin / Q000009:adverse effects* / Q000627:therapeutic use; D004407:Dysgerminoma / Q000188:drug therapy; D005385:Fingers; D006801:Humans; D008297:Male; D011928:Raynaud Disease / Q000139:chemically induced*; D012598:Sclerosis / Q000139:chemically induced*; D013736:Testicular Neoplasms / Q000188:drug therapy
D001761:Bleomycin