An immuno-electronmicroscopical study comparing vasopressin, oxytocin, substance P and enkephalin containing nerve terminals in the nucleus of the solitary tract of the rat.
Vasopressin, oxytocin, substance P and enkephalin fibers were demonstrated to terminate synaptically in the nucleus of the solitary tract. The detergent Triton X-100 proved to be indispensable for the demonstration of vasopressin and oxytocin while enkephalin and substance P could be visualized very well without it. The differences with respect to morphology between these 4 peptides disappeared when Triton X-100 was used in both groups.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D004745:Enkephalins / Q000032:analysis*; D007118:Immunoassay; D008526:Medulla Oblongata / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure*; D010121:Oxytocin / Q000032:analysis*; D051381:Rats; D013373:Substance P / Q000032:analysis*; D014667:Vasopressins / Q000032:analysis*
D004745:Enkephalins; D014667:Vasopressins; D013373:Substance P; D010121:Oxytocin