title: [Systemic side-effects of topical preparations in children (author's transl)].
abstract: Any topical treatment may lead to systemic side-effects through epidermal penetration. In children the ratio surface treated/weight is usually high, implying greater risk. Factors which determine percutaneous absorption in childhood are reviewed as well as the main drugs which are toxic when applied to the skin.
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000009:adverse effects* / Q000378:metabolism; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D002648:Child; D003879:Dermatologic Agents / Q000009:adverse effects* / Q000378:metabolism; D005938:Glucocorticoids; D001556:Hexachlorocyclohexane / Q000009:adverse effects; D006582:Hexachlorophene / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007455:Iodine / Q000008:administration & dosage / Q000009:adverse effects; D007641:Keratolytic Agents / Q000009:adverse effects; D012532:Scabies / Q000188:drug therapy; D012869:Skin Absorption
chemical_list: D000891:Anti-Infective Agents, Local; D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids; D007641:Keratolytic Agents; D001556:Hexachlorocyclohexane; D007455:Iodine; D006582:Hexachlorophene
vernacular_title: Risques systémiques des médicaments topiques chez l'enfant.