Inhibition of human serum alpha-amylase activity.
Amylase activity was measured in normal sera and serum of patients with acute pancreatitis and mumps. A significant decrease of enzyme activity in patients with acute pancreatitis was observed after incubation with specific antibody against hog pancreas amylase. A minimal effect of the antibody on normal serum and on that from mumps patients was noted. A comparable effect was observed in the presence of glyceraldehyde used as an amylase differentiating factor.
D000293:Adolescent; D000328:Adult; D000681:Amylases / Q000037:antagonists & inhibitors*; D000818:Animals; D000918:Antibody Specificity; D005260:Female; D005985:Glyceraldehyde / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009107:Mumps / Q000201:enzymology; D010179:Pancreas / Q000201:enzymology*; D010195:Pancreatitis / Q000201:enzymology; D013552:Swine; D000516:alpha-Amylases / Q000037:antagonists & inhibitors* / Q000097:blood / Q000276:immunology
D005985:Glyceraldehyde; D000681:Amylases; D000516:alpha-Amylases