Angiogenesis of cultured endothelial cells of bovine coronary artery.
Endothelial cells of bovine coronary artery were isolated and cultivated and bovine clots were placed in the cultured endothelial cells (42 generations), followed by observation on the 14th day. Cultured endothelial cells not only covered the surface of each clot but also migrated in it to form oval or irregularly shaped intracytoplasmic vacuoles or sometimes intercellular vacuoles surrounded by 2 or 3 cells. Some of these vacuoles contained membranous materials. This vacuolization was considered to represent angiogenetic activity peculiar to endothelial cells.
D000818:Animals; D001158:Arteries / Q000473:pathology; D002417:Cattle; D002478:Cells, Cultured; D003331:Coronary Vessels / Q000473:pathology* / Q000648:ultrastructure; D004727:Endothelium / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009389:Neovascularization, Pathologic / Q000473:pathology*; D014617:Vacuoles / Q000648:ultrastructure