Monoclonal antibody reactive with both p28 and p19 of adult T-cell leukemia virus-specific polypeptides.
Mouse monoclonal antibodies, GIN-2, -7 and -14, against adult T-cell leukemia virus (ATLV) were prepared by a hybridoma procedure. These antibodies belonged to different subclasses of IgG, but they reacted similarly with both ATLV-specific polypeptides p19 and p28. In the reaction with monoclonal antibodies and various ATLV-producer cell lines, it was found that MT-2 and MT-2-related T-cell lines produced both p19 and p28, whereas MT-2-unrelated cell lines produced p19, but not p28.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D002460:Cell Line; D002472:Cell Transformation, Viral; D000939:Epitopes; D006801:Humans; D007938:Leukemia / Q000382:microbiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D010455:Peptides / Q000276:immunology*; D012190:Retroviridae / Q000276:immunology*; D013601:T-Lymphocytes
D000911:Antibodies, Monoclonal; D000939:Epitopes; D010455:Peptides