Immunological cross-reactivity between H-2Dk product and DTIC-treated H-2d lymphoma.
The experiments reported here concern the characterization by techniques of in vitro cell-mediated immunity of the antigens induced by 5-(3,3' dimethyl-1-triazine)-imidazole-4-carboxamide (DTIC) on L1210, a chemically-induced lymphoma of DBA/2 mice (H-2d). This series of experiments with the DTIC-treated L1210 tumour show the presence of an 'H-2D'-like antigen which resembles the Dk gene product/s of the H-2k haplotype.
D000818:Animals; D003429:Cross Reactions; D003606:Dacarbazine / Q000627:therapeutic use*; D000939:Epitopes; D006183:H-2 Antigens / Q000276:immunology*; D007111:Immunity, Cellular; D066298:In Vitro Techniques; D007939:Leukemia L1210 / Q000188:drug therapy / Q000276:immunology; D008223:Lymphoma / Q000188:drug therapy / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains
D000939:Epitopes; D006183:H-2 Antigens; D003606:Dacarbazine