title: [Ct-morphology and exocrine function in chronic pancreatitis].
abstract: A quantitative correlation between computer-tomographic (CT) findings and exocrine pancreatic function following secretin-ceruletide stimulation was performed in 48 patients with chronic pancreatitis; thereby a significant correlation between the degree of morphological changes in CT and the stage of functional impairment was found (r = 0,7841, p less than 0,001). Bicarbonate secretion/h showed the strongest correlation to CT findings (r = -0,7193, p less than 0,001) within the single functional parameters. CT showed a limited sensitivity (50%) in detecting chronic pancreatitis in cases with a slight functional impairment (stage 1). Morphological signs as calcifications, pancreatic duct ectasia were constantly coupled with a severe degree of functional impairment, whereas enlargement and cysts were found throughout the different functional stages.
mesh_terms: D000328:Adult; D000368:Aged; D000681:Amylases / Q000378:metabolism; D001639:Bicarbonates / Q000378:metabolism; D002108:Ceruletide; D002908:Chronic Disease; D002918:Chymotrypsin / Q000378:metabolism; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000378:metabolism / Q000503:physiopathology*; D010195:Pancreatitis / Q000000981:diagnostic imaging*; D012633:Secretin; D014057:Tomography, X-Ray Computed; D014357:Trypsin / Q000378:metabolism
chemical_list: D001639:Bicarbonates; D012633:Secretin; D002108:Ceruletide; D000681:Amylases; D002918:Chymotrypsin; D014357:Trypsin
vernacular_title: CT-Morphologie und exokrine Funktion bei chronischer Pankreatitis.