Cell membrane abnormality detected in erythrocytes from patients with multiple sclerosis by partition in two-polymer aqueous-phase systems.
Erythrocytes from multiple sclerosis patients differ significantly (p less than 0.005) from those from controls with regard to hydrophobic affinity partition in two-polymer aqueous-phase systems containing dextran, poly(ethylene glycol) and poly (ethylene glycol)-fatty acid esters. The most likely source of the abnormality is the cell membrane.
D002469:Cell Separation / Q000379:methods*; D003911:Dextrans; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D019787:Linoleic Acid; D008041:Linoleic Acids; D008563:Membrane Lipids / Q000378:metabolism; D009103:Multiple Sclerosis / Q000097:blood*; D011092:Polyethylene Glycols; D013228:Stearates
D003911:Dextrans; D008041:Linoleic Acids; D008563:Membrane Lipids; D013228:Stearates; D011092:Polyethylene Glycols; D019787:Linoleic Acid