[Trophoblastic beta-globulin in immunoglobulin preparations].
The content of trophoblastic beta-globulin in 142 lots of commercial immunoglobulin preparations from 20 manufacturers, produced from placental, abortion and donor blood sera, has been studied. 83% of lots from abortion blood serum and 94% of lots from placental blood serum have been found to contain the admixture of this beta-globulin, its concentration in the lots from placental blood serum being significantly higher. The method for the detection of trophoblastic beta-globulin may be used for evaluating the quality of immunoglobulin preparations as it indicates the degree of their purification from placental proteins.
D000022:Abortion, Spontaneous / Q000276:immunology; D001609:Beta-Globulins / Q000032:analysis*; D001789:Blood Group Antigens / Q000276:immunology; D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D010920:Placenta / Q000276:immunology; D011247:Pregnancy; D014327:Trophoblasts / Q000276:immunology*
D001609:Beta-Globulins; D001789:Blood Group Antigens; D006063:Chorionic Gonadotropin; D007136:Immunoglobulins
Trofoblasticheskiĭ beta-globulin v preparatakh immunoglobulinov.