title: Isolation and characterization of three cloned fragments of human DNA coding for tRNAs and small nuclear RNA U1.
abstract: Employing a human fetal liver library in lambda Charon 4A phage vector, we have isolated and characterized three clones of human DNA containing genes for tRNAs. One clone contains at least three tRNA genes (tRNALys, tRNAGln and tRNALeu) within 2 kb of each other. The other two clones contain two different single genes for tRNAAsn. One of these latter two DNAs also contains a gene for U1 small nuclear RNA.
mesh_terms: D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification*; D004262:DNA Restriction Enzymes; D005260:Female; D005333:Fetus; D006801:Humans; D008099:Liver / Q000196:embryology / Q000378:metabolism; D011247:Pregnancy; D012313:RNA / Q000235:genetics*; D012342:RNA, Small Nuclear; D012343:RNA, Transfer / Q000235:genetics*
chemical_list: D012342:RNA, Small Nuclear; D012313:RNA; D004247:DNA; D012343:RNA, Transfer; D004262:DNA Restriction Enzymes