The fatty acid levels of rat alpha-fetoprotein derived from fetuses, pregnancy and hepatoma sera.
The fatty acid levels of alpha-fetoprotein (AFP) isolated from term rat fetuses is about half that of similar human preparations. Arachidonic and docosahexaenoic acids constitute about 33% of the total fatty acids in the rat AFP isolates. The AFP isolated from rat maternal and hepatoma sera have relatively low levels of these fatty acids. A comparison of the fatty acid contents of selected tissues from pregnant and non-pregnant rats does not show differences which might reflect the variable fatty acid levels of the fetal and maternal source AFP preparations.
D000818:Animals; D001095:Arachidonic Acids / Q000302:isolation & purification; D006528:Carcinoma, Hepatocellular / Q000097:blood*; D004281:Docosahexaenoic Acids; D005227:Fatty Acids / Q000302:isolation & purification*; D005231:Fatty Acids, Unsaturated / Q000302:isolation & purification; D005260:Female; D005333:Fetus; D006801:Humans; D007525:Isoelectric Focusing; D008113:Liver Neoplasms / Q000097:blood*; D008114:Liver Neoplasms, Experimental / Q000097:blood; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D000509:alpha-Fetoproteins / Q000302:isolation & purification*
D001095:Arachidonic Acids; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D000509:alpha-Fetoproteins; D004281:Docosahexaenoic Acids