Modulation of phagocytosis.
In conclusion, the earlier reports on the phagocytosis-enhancing effect of interferon have now been widely confirmed. Interferon not only activates non-Fc-receptor-mediated phagocytosis such as colloidal carbon or latex beads, but also stimulates Fc-receptor-mediated ingestion of IgG-coated erythrocytes. However, it should be cautioned that all inducers of interferon do not depend on the interferon they stimulate to activate macrophages. The notion that interferon may be a very nonspecific yet crucial factor in the basic defense mechanisms of the body has been further reinforced.
D000818:Animals; D004912:Erythrocytes; D007074:Immunoglobulin G; D007369:Interferon Inducers / Q000494:pharmacology; D007372:Interferons / Q000302:isolation & purification / Q000494:pharmacology*; D008262:Macrophage Activation; D009522:Newcastle disease virus / Q000276:immunology; D010587:Phagocytosis / Q000187:drug effects*; D011961:Receptors, Fc / Q000187:drug effects / Q000502:physiology; D012756:Sheep
D007074:Immunoglobulin G; D007369:Interferon Inducers; D011961:Receptors, Fc; D007372:Interferons