title: Penicillin activity in brain tissue: a method for continuous measurement.
abstract: A double-barrelled microelectrode is described which permits the continuous and simultaneous measurement of penicillin concentration and of the local bioelectric activity in nervous tissue. The electrode, which is based on a chloride ligand (Corning no. 477315), has a short response time and enables reproducible measurements of penicillin concentration even below 500 IU/ml.
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology; D004827:Epilepsy / Q000139:chemically induced*; D008839:Microelectrodes; D010406:Penicillins; D012377:Rodentia
chemical_list: D010406:Penicillins