Hypertrophy of neurons in dorsal lateral geniculate nucleus following striate cortex lesions in infant monkeys.
Monkeys whose left striate cortex had been removed in infancy received bilateral injections of horseradish peroxidase (HRP) into the prelunate gyrus (PLG) prestriate cortex. Scattered large neurons in the dorsal lateral geniculate nucleus were retrogradely labeled in both hemispheres. On the lesioned side, the HRP-labeled cell bodies were 58% larger in area, showing an overall increase in soma size and complexity of dendritic field, suggesting a hypertrophy of the geniculate-PLG pathway following a neonatal striate cortex lesion.
D000818:Animals; D001370:Axonal Transport; D005829:Geniculate Bodies / Q000473:pathology*; D006735:Horseradish Peroxidase; D006984:Hypertrophy; D008254:Macaca nemestrina; D008297:Male; D009474:Neurons / Q000166:cytology*; D014793:Visual Cortex / Q000502:physiology*
D006735:Horseradish Peroxidase