title: [Antiprotease activity of the blood serum of patients with the disseminated form of breast cancer before and after combined treatment].
abstract: The paper discusses the results of a study on the blood-serum levels of alpha 1-antitrypsin and alpha 2-macroglobulin in 29 patients with an extensive breast cancer before and within 3 years after a combination therapy including proton "hypophysectomy". A correlation was established between the blood level of alpha 1--antitrypsin and the subclinical stage of generalized metastatic spreading. Consequently, the assay of the level of this inhibitor is suggested as another test for assessment of the efficacy of treatment of such patients and prediction of the results.
mesh_terms: D000328:Adult; D000368:Aged; D000510:Alpha-Globulins / Q000032:analysis; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy; D004796:Clinical Enzyme Tests; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010910:Pituitary Irradiation; D011379:Prognosis; D011480:Protease Inhibitors / Q000097:blood*; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D000510:Alpha-Globulins; D011480:Protease Inhibitors; D000515:alpha 1-Antitrypsin; C025500:alpha(2)-microglobulin
vernacular_title: Antiproteaznaia aktivnost' syvorotki krovi bol'nykh rasprostranennoĭ formoĭ raka molochnoĭ zhelezy do i posle kompleksnogo lecheniia.