[Metabolic and ultrastructural characteristics of myocardial contraction in experimental small focal myocardial infarction].
In dogs, pituitrin increases, and isadrin reduces, the tonicity of coronary arteries. Successive administration of the two agents to rabbits causes functional and metabolic unbalance of the heart, with resultant myocardial necrotic foci in the presence of blood hypercoagulation and heart muscle contractility disordered. The disorder of cardiomyocyte stereo architectonics is an essential element of the pathophysiologic mechanism of small-focal myocardial infarction.
D000227:Adenine Nucleotides / Q000378:metabolism; D000818:Animals; D001777:Blood Coagulation; D004247:DNA / Q000378:metabolism; D004285:Dogs; D005260:Female; D008297:Male; D008929:Mitochondria, Heart / Q000378:metabolism; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D009206:Myocardium / Q000378:metabolism* / Q000648:ultrastructure; D010085:Oxidative Phosphorylation; D012313:RNA / Q000378:metabolism; D011817:Rabbits
D000227:Adenine Nucleotides; D012313:RNA; D004247:DNA
Metabolicheskaia i ul'trastrukturnaia kharakteristika sokratitel'noĭ funktsii serdtsa pri éksperimental'nom melkoochagovom porazhenii miokarda.