title: [Roentgeno-morphological pulmonary changes following bleomycin therapy].
abstract: 100 patients with squamous cell carcinoma of the head and neck, who underwent a bleomycin therapy pre- and postoperative have been followed up retrospectively for radiological signs of bleomycin-typical side-effects of the lung. The frequency of such changes was 24% and there were 2 peaks after 1 week and 4-6 weeks from the start of therapy. An increased risk to develop an interstitial exsudation and fibrosis seems to exist only for patients with preexistent emphysema of the lung.
mesh_terms: D000328:Adult; D001761:Bleomycin / Q000009:adverse effects* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D011656:Pulmonary Emphysema / Q000150:complications; D011859:Radiography; D012306:Risk
chemical_list: D001761:Bleomycin
vernacular_title: Röntgenmorphologische Lungenveränderungen nach Bleomycin-Therapie.