[Accumulation of radiolabeled alpha fetoprotein in spontaneous mammary tumors in mice].
Radiolabelled alphafetoprotein (AFP) was selectively concentrated by spontaneous mammary carcinomas of the Mouse. External photoscans of Mice injected with 131I-AFP confirmed the significant accumulation of the protein in the tumors. These results prove the usefulness of AFP as a radiotracer for mammary carcinomas and represent a novel approach for tumor detection.
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000378:metabolism*; D000818:Animals; D005260:Female; D007457:Iodine Radioisotopes; D008325:Mammary Neoplasms, Experimental / Q000000981:diagnostic imaging / Q000378:metabolism*; D051379:Mice; D008815:Mice, Inbred Strains; D011877:Radionuclide Imaging; D000509:alpha-Fetoproteins / Q000378:metabolism*
D007457:Iodine Radioisotopes; D000509:alpha-Fetoproteins
Accumulation d'alphafétoprotéine radiomarquée dans des tumeurs mammaires spontanées de la Souris.