title: Antigenic relatedness of pigeon herpes encephalomyelitis virus to other avian herpesviruses.
abstract: Pigeon herpes encephalomyelitis virus (PHEV) was compared with seven avian herpesviruses for antigenic relatedness using monospecific antisera and the indirect fluorescent-antibody (IFA), agar-gel-immunodiffusion, and serum-neutralization tests. No antigenic relationship was detected between PHEV and Marek's disease virus, turkey herpesvirus, infectious laryngotracheitis virus, and duck enteritis virus. A common precipitating antigen was detected between the PHEV and pigeon herpesvirus (PHV), owl herpesvirus (OHV), and falcon herpesvirus (FHV). These four viruses also cross-reacted in the IFA test. Weak neutralizing activity was detected only between PHV antiserum and PHEV. These results suggest that the PHEV should be classified as a herpesvirus related to, but distinct from, the PHV-OHV-FHV group of viruses with which it shares common antigens.
mesh_terms: D000818:Animals; D010856:Columbidae / Q000382:microbiology*; D003429:Cross Reactions; D004679:Encephalomyelitis / Q000382:microbiology / Q000662:veterinary*; D000939:Epitopes / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006564:Herpesviridae / Q000276:immunology*; D005779:Immunodiffusion / Q000662:veterinary; D009500:Neutralization Tests
chemical_list: D000939:Epitopes