[Visualization of different types of hapten-cell membrane interaction by fluorine high-field nuclear magnetic resonance].
Using a high field spectrometer (5.9 Tesla) 19F-NMR spectrum of soluble material from 4 trifluoromethyl 2,6 dinitrobenzene sulphonate (CF3-DNBS) treated murine lymphocytes was recorded. CF3-DNBS is a fluorinated analog of 2,4,6 trinitrobenzene sulphonate (TNBS), and these compounds have been found to create cross-reacting antigenic modifications of cell surface. At least 4 distinguishable signals have been detected, and we think that 19F-NMR could be used to study, at a molecular level, some immunochemical problems concerning modification with TNBS.
D000818:Animals; D001557:Benzenesulfonates / Q000276:immunology*; D002462:Cell Membrane / Q000276:immunology*; D000939:Epitopes; D006241:Haptens / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008808:Mice, Inbred CBA
D001557:Benzenesulfonates; D000939:Epitopes; D006241:Haptens; C025388:2,6-dinitro-4-trifluoromethylbenzenesulfonic acid
Visualisation, par résonance magnétique nucléaíre du fluor a haut-champ, de différents types d'interaction haptène-membrane cellulaire.