Higher cytolytic efficiency of an IgG2 alpha than of an IgG1 monoclonal antibody reacting with the same (or spatially close) determinant on a human high-molecular-weight melanoma-associated antigen.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D003602:Cytotoxicity, Immunologic; D000939:Epitopes; D006801:Humans; D007074:Immunoglobulin G / Q000145:classification / Q000276:immunology*; D008545:Melanoma / Q000276:immunology*; D058950:Melanoma-Specific Antigens; D051379:Mice; D008809:Mice, Inbred C3H; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000276:immunology*; D011817:Rabbits
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000939:Epitopes; D007074:Immunoglobulin G; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins