Detection of antibodies to strain-specific and cross-reactive antigenic determinants on the haemagglutinin of influenza viruses A/Texas/1/77 and A/Bangkok/1/79 in human sera. Brief report.
The antibody response to antigenic determinants on the haemagglutinin molecule of A/Texas/77 and A/Bangkok/79 strains was analysed by SRH of virus-absorbed sera, in human sera collected from persons of different ages following natural infection or immunization. The results have shown, as expected, low and high frequencies of strain-specific antibodies in sera of adults and young children respectively. However, in the latter group antibodies to cross-reactive antigens were also detected.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions; D000939:Epitopes / Q000276:immunology*; D005260:Female; D006389:Hemagglutinins, Viral / Q000276:immunology*; D006801:Humans; D007114:Immunization; D005779:Immunodiffusion; D007223:Infant; D007231:Infant, Newborn; D009980:Influenza A virus / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D000939:Epitopes; D006389:Hemagglutinins, Viral