Isolation of an active glucoside in bracken fern, Pteridium aquilinum.
An active glucoside that enhanced release of histamine from rat peritoneal mast cells was isolated from a toxic fraction of bracken fern, Pteridium aquilinum, by partition column chromatography on Sephadex G-25. It was a yellowish amorphous powder on freeze-drying, readily soluble in water or ethanol, and insoluble in ether. It was hydrolysed with beta-glucosidase to release D-glucose. It was assumed to be a kind of beta-glucopyranoside with a carbocyclic structure in the aglycone moiety.
D000818:Animals; D002273:Carcinogens; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification*; D006636:Histamine Release / Q000187:drug effects; D008297:Male; D010947:Plants, Toxic / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D002273:Carcinogens; D005960:Glucosides; D006027:Glycosides