[Effect of ketotifen and oxatomide on histamine liberation due to exposure in cold urticaria].
Four patients suffering from cold urticaria were treated with ketotifen and oxatomide for one week each. Histamine liberation was measured after the exposure to cold before and after the treatment. A significant inhibition was demonstrated for either product, much more so, however, for oxatomide. This inhibition was associated with a pronounced improvement of complaints.
D000328:Adult; D003080:Cold Temperature / Q000009:adverse effects*; D005260:Female; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans; D007665:Ketotifen / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000494:pharmacology*; D014581:Urticaria / Q000188:drug therapy* / Q000209:etiology
D006634:Histamine H1 Antagonists; D010879:Piperazines; C015408:oxatomide; D007665:Ketotifen
Einfluss von Ketotifen und Oxatomid auf die expositions-bedingte Histaminfreisetzung bei Kälteurtikaria.