Effect of polycations and polyanions on cell division of cultured mammalian cells.
The polycations (H1 histone and polylysine) and polyanions (heparin and various RNA preparations) stimulate cell division of cultured mammalian cells. The mechanisms by which both polycations (H1 histone and polylysine) and polyanions (heparin and RNA) may increase the rate of cell division are discussed.
D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D006493:Heparin / Q000494:pharmacology*; D006657:Histones / Q000494:pharmacology*; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology; D051379:Mice; D008970:Molecular Weight; D010455:Peptides / Q000494:pharmacology*; D011070:Poly I-C / Q000494:pharmacology; D011067:Poly dA-dT / Q000494:pharmacology; D011107:Polylysine / Q000494:pharmacology*; D012313:RNA / Q000494:pharmacology*; D012335:RNA, Ribosomal / Q000494:pharmacology; D012343:RNA, Transfer / Q000494:pharmacology; D013997:Time Factors
D006657:Histones; D010455:Peptides; D012335:RNA, Ribosomal; D011107:Polylysine; D011067:Poly dA-dT; D012313:RNA; D006493:Heparin; D012343:RNA, Transfer; D011070:Poly I-C