Contact allergy to 2-hydroxypropyl methacrylate (2-HPMA) in an ultraviolet curable ink.
A patient working in an ink laboratory developed dermatitis on his hands. Patch testing revealed contact allergy to the ink used and to 2-hydroxypropyl methacrylate (2-HPMA), the monomer present in the ink. Guinea pig maximisation test (GPM-test) shows that 2-HPMA is a weak sensitizer. The data suggest cross-reactivity to 2-hydroxyethyl methacrylate (2-HEMA) but not to 2-hydroxypropyl acrylate (2-HPA) or 2-hydroxyethyl acrylate (2-HEA).
D000179:Acrylates / Q000009:adverse effects*; D000485:Allergens / Q000008:administration & dosage; D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology* / Q000276:immunology; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000276:immunology; D006168:Guinea Pigs; D006229:Hand Dermatoses / Q000139:chemically induced*; D006801:Humans; D007281:Ink; D008297:Male; D008689:Methacrylates / Q000009:adverse effects*; D008875:Middle Aged; D010328:Patch Tests
D000179:Acrylates; D000485:Allergens; D008689:Methacrylates; C029639:2-hydroxypropyl methacrylate