5-HIAA Levels in brain and cerebrospinal fluid of the neonatal rat during oxygen deprivation.
Neonatal rats were exposed to a moderate asphyxia (6% O2-94% N2 for 30 min). During asphyxia, whole brain 5-hydroxyindoleacetic acid (5-HIAA) levels were reduced by approximately 25%. In the recovery period, a rebound increase (60%) was found 2 h after asphyxia. Cerebrospinal fluid 5-HIAA levels did not change during or after oxygen deficiency.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001923:Brain Chemistry; D006897:Hydroxyindoleacetic Acid / Q000032:analysis* / Q000134:cerebrospinal fluid; D000860:Hypoxia / Q000134:cerebrospinal fluid / Q000378:metabolism*; D008995:Monoamine Oxidase / Q000032:analysis; D051381:Rats / Q000502:physiology*; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D008995:Monoamine Oxidase