Termination of ouabain-induced cardiac arrhythmias by anterior hypothalamic stimulation.
Digitalis-toxic ventricular arrhythmias were produced in cats by repeated injections of ouabain. These arrhythmias converted to normal sinus rhythm significantly faster in cats receiving anterior hypothalamic stimulation than in sham stimulated controls. This effect was uncorrelated with changes in sympathetic activity along the renal nerve.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000503:physiopathology*; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004558:Electric Stimulation; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D007032:Hypothalamus, Anterior / Q000502:physiology*; D010042:Ouabain / Q000494:pharmacology*; D012313:RNA / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000502:physiology
D010042:Ouabain; D012313:RNA