Antigenic cross-reactivities between mammalian hexokinases.
Immunoelectrophoresis and gel diffusion techniques have demonstrated that, contrary to previous reports, antigenic cross-reactivity does exist between the three major rat hexokinase isoenzymes. Immune inhibition and immune precipitation assays performed in parallel generally failed to detect this cross-reactivity and possible reasons for this failure are discussed. The inability of the latter assay systems to detect cross-reactivity would seem to account for the discrepancies between the present results and those obtained in earlier studies.
D000818:Animals; D000936:Antigen-Antibody Complex; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis*; D006593:Hexokinase / Q000276:immunology* / Q000378:metabolism; D007106:Immune Sera; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007527:Isoenzymes / Q000276:immunology*; D013045:Species Specificity
D000936:Antigen-Antibody Complex; D000939:Epitopes; D007106:Immune Sera; D007527:Isoenzymes; D006593:Hexokinase