title: Econometric analysis of phase duration for blood morphology and basophil count alterations in chronic granulocytic leukaemia.
abstract: The retrospective analysis of 40 cases with chronic granulocytic leukemia revealed an average survival time of 39 months. Modal proportions between the chronic, accelerated and acute blastic crisis amounted to 25:6:8 months. The characteristic points and curves for peripheral white cell, blast cell, basophil cell and thrombocyte counts as well as haemoglobin levels were determined separately in 20 patients with long and in 20 with short survival time. Comparisons indicate among others that Busulphan sensitivity is an essential factor for a longer survival time of CGL patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001491:Basophils; D002066:Busulfan / Q000627:therapeutic use; D002648:Child; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy / Q000401:mortality*; D007958:Leukocyte Count; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D008962:Models, Theoretical; D010976:Platelet Count
chemical_list: D006454:Hemoglobins; D002066:Busulfan