Current understanding of lidocaine as an antiarrhythmic agent: a review.
Lidocaine generally is the agent of first choice against acute ventricular arrhythmias arising from many causes. It is clinically effective and well tolerated, having a rapid onset of action and a favorable electrophysiological profile. Unlike other antiarrhythmic agents, lidocaine does not interact with the autonomic nervous system. A review of the literature highlights current knowledge about this antiarrhythmic drug.
D000367:Age Factors; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D005117:Cardiac Complexes, Premature / Q000517:prevention & control; D004594:Electrophysiology; D006329:Heart Conduction System / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008956:Models, Chemical; D009203:Myocardial Infarction / Q000150:complications; D009420:Nervous System / Q000187:drug effects; D013610:Tachycardia / Q000517:prevention & control
D008012:Lidocaine