Apneas and oscillation of cardiac ectopy in Cheyne-Stokes breathing during sleep.
Previous investigators have described heart rate oscillations (1,2) and various arrhythmias (3-5) during Cheyne-Stokes breathing. To our knowledge, however, this is the first report describing cardiac ectopic beats oscillating with the identical frequency as ventilatory movement and SaO2 in Cheyne-Stokes breathing during sleep. This case is also the first to document with polygraphic sleep recordings the suggested efficacy of acetazolamide (26) in abolishing the apneas of Cheyne-Stokes breathing during sleep. However, generalizations regarding the impact of ventilation on cardiac ectopy and the therapeutic effect of acetazolamide will require prospective studies on multiple patients with Cheyne-Stokes breathing during sleep.
D000086:Acetazolamide / Q000627:therapeutic use*; D000368:Aged; D005117:Cardiac Complexes, Premature / Q000503:physiopathology*; D002639:Cheyne-Stokes Respiration / Q000188:drug therapy / Q000503:physiopathology*; D004562:Electrocardiography; D006329:Heart Conduction System / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D008297:Male; D012119:Respiration; D012120:Respiration Disorders / Q000503:physiopathology*; D012891:Sleep Apnea Syndromes / Q000188:drug therapy / Q000503:physiopathology*
D000086:Acetazolamide