Alteration of mast cell cyclic AMP levels and its relationship by byssinosis.
Alteration of mast cell cyclic AMP levels have been implicated in the acute respiratory symptoms in mill workers following inspiration of cotton, flax, or hemp textile dusts. This paper describes the inverse relationship between the cellular levels of cyclic AMP and the degranulation in pure culture of mast cells in response to aqueous cotton bract extracts of glanded and glandless varieties.
D000818:Animals; D002095:Byssinosis / Q000378:metabolism; D000242:Cyclic AMP / Q000032:analysis*; D003368:Gossypium / Q000009:adverse effects; D006636:Histamine Release; D008297:Male; D008407:Mast Cells / Q000032:analysis* / Q000187:drug effects / Q000473:pathology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats
D011433:Propranolol; D000242:Cyclic AMP