title: Brain stem projections from cortical area 18 in the albino rat.
abstract: Efferent brain stem projections from area 18 of the albino rat cortex were traced by autoradiography. Since results could have been compromised by spread of injected label to neighboring areas 17 and 29, studies of projections from these areas were used as controls. A hitherto unreported projection from area 18 to the thalamus in the region of its anterior nuclei was found, terminating in a roughly circular area including parts of the anteromedial, ventral, ventromedial and rhomboid nuclei. At this same level, a very light projection was seen in the contralateral anteromedial nucleus. More caudally the projection pattern was similar to that of area 17, with the lateral, lateral posterior, posterior and pretectal nuclei as targets. However, area 18 showed no projections to either division of lateral geniculate nucleus, projections which are commonly seen following injections in area 17. More caudally, the area 18 projection to the superior colliculus was confined to its four deepest laminae, a projection identical to that from areas 29c and 29b. Area 18 also resembled the cingulate cortex in that it sent a small projection to the dorsolateral central gray, although the routes taken to this region were slightly different. It was decided that the projections from this visual association area were, for the most part, unique to that area, although some of them resembled those from either the cingulate cortex or the primary visual area.
mesh_terms: D000818:Animals; D001345:Autoradiography; D001370:Axonal Transport; D001921:Brain / Q000033:anatomy & histology*; D001933:Brain Stem / Q000033:anatomy & histology*; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D004525:Efferent Pathways / Q000033:anatomy & histology; D007930:Leucine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium; D014793:Visual Cortex / Q000033:anatomy & histology
chemical_list: D014316:Tritium; D007930:Leucine