[ACD-AG blood with decreased adenine and guanosine content].
ACD-AG blood with 2 different initial concentrations of adenine and guanosine--both 0.25 and 0.5 mmol/l, respectively--has been studied by using 13 parameters. Differences could not be found in 11 parameters, among them ATP and 2,3-P2G content and the number of microaggregates. The formation of lactate and the hemolyses rate were slightly increased during 6 weeks. But the mean hemolysis rate was below 1%. A sufficient maintenance of red cell metabolism at lower adenine and guanosine concentrations as found in ACD-AG blood can also be supposed for the preservation of buffy coat-free red cell concentrates.
D000225:Adenine / Q000097:blood*; D001793:Blood Preservation; D019343:Citric Acid; D005260:Female; D005947:Glucose / Q000031:analogs & derivatives*; D006151:Guanosine / Q000097:blood*; D006801:Humans; D008297:Male
D006151:Guanosine; C002113:acid citrate dextrose; D019343:Citric Acid; D005947:Glucose; D000225:Adenine
ACD-AG-Blut mit verringertem Adenin- und Guanosingehalt.