Chromatin structure and expression of amylase genes in rat pituitary tumor cells.
Amylase-coding sequences were detected in the population of cytoplasmic RNA molecules from cultured rat pituitary GH3 cells. The amylase genes in these cells are in a micrococcal nuclease-sensitive, transcriptionally active chromatin conformation. The amount of cytoplasmic amylase mRNA appears to be controlled by small molecules provided by the fetal calf serum component of the culture medium.
D000681:Amylases / Q000235:genetics*; D000818:Animals; D002478:Cells, Cultured; D002843:Chromatin / Q000302:isolation & purification*; D005786:Gene Expression Regulation; D005796:Genes; D009374:Neoplasms, Experimental / Q000235:genetics; D010911:Pituitary Neoplasms / Q000201:enzymology / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics; D012334:RNA, Neoplasm / Q000235:genetics; D051381:Rats; D014158:Transcription, Genetic; D000516:alpha-Amylases / Q000235:genetics*
D002843:Chromatin; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D000681:Amylases; D000516:alpha-Amylases