Production of antibody against C3c epitopes which are inaccessible on native C3.
Anti-C3c antiserum was induced by immunizing rabbits with autologous erythrocytes coated with human C3b/C3bi. By absorption with human plasma this antiserum was rendered specific for C3c epitopes which are not expressed on native C3. This specificity may be analogous to that of immunoconglutinin.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D003176:Complement C3 / Q000276:immunology*; D015932:Complement C3c; D000939:Epitopes / Q000276:immunology*; D004910:Erythrocyte Membrane / Q000276:immunology; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D011817:Rabbits
D000906:Antibodies; D003176:Complement C3; D000939:Epitopes; D015932:Complement C3c