Desensitisation of rat thyroid to the growth-stimulating action of TSH during prolonged goitrogen administration. Persistence of refractoriness following withdrawal of stimulation.
D000640:Amitrole / Q000494:pharmacology*; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D002452:Cell Count; D008297:Male; D008938:Mitosis / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000187:drug effects; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D014230:Triazoles / Q000494:pharmacology*; D014284:Triiodothyronine / Q000097:blood
D013956:Antithyroid Agents; D014230:Triazoles; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine; D000640:Amitrole