Comparison of lytic and persistent measles virus matrix proteins by competition radioimmunoassay.
Measles virus matrix (M) proteins were compared by competitive monoclonal antibody-binding studies. Three strains of measles and of subacute sclerosing panencephalitis viruses were found to be identical in this way. The matrix protein formed by Edmonston strain virus during a persistent infection could be distinguished from that made in the lytic virus infection. It is concluded that structural alterations in the M peptide can occur during persistence.
D000911:Antibodies, Monoclonal; D000915:Antibody Affinity; D000939:Epitopes / Q000032:analysis; D008459:Measles virus / Q000032:analysis*; D011863:Radioimmunoassay; D013190:SSPE Virus / Q000032:analysis*; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000032:analysis / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000939:Epitopes; D014763:Viral Matrix Proteins; D014764:Viral Proteins