title: [Cytotoxic antiglobulin test--a sensitive method for HLA typing].
abstract: By using of 1:1000 of diluted antiglobulin sera the cytotoxic antiglobulin test also covers HLA antigens in 20% of those cases which cannot be identified by normal microlymphocytotoxic tests. The percentage of not specifically faulty positive results is lower than 5%. The method can be used for typing HLA antigens in all those cases where a decreased expressiveness of HLA antigens can be expected as well as for determining weak HLA cytotoxins. The use of undiluted antiglobulin sera, however, leads to unspecific positive results in 1/4 of the cases. The reasons for this phenomenon are being investigated and discussed.
mesh_terms: D003298:Coombs Test; D003601:Cytotoxicity Tests, Immunologic; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans
chemical_list: D006680:HLA Antigens
vernacular_title: Der zytotoxische Antiglobulintest--eine empfindliche Methode für die HLA-Typisierung.