Subarachnoid neurolytic block (L5-S1) and unilateral percutaneous cervical cordotomy in the treatment of pain secondary to pelvic malignant disease.
The present study deals with the immediate and long-term results of subarachnoid neurolytic block (L5-S1) with 7.5%, 10% and 15% concentrations of phenol in glycerine and/or unilateral percutaneous cervical cordotomy in 73 patients (follow-up in 56 patients) suffering from perineal, perineopelvisacral or pelvisacral pain secondary to malignant diseases of the pelvic cavity. Subarachnoid neurolytic block (L5-S1) produced satisfactory, long-lasting relief of perineal pain when the higher concentrations of phenol (10 and 15%) were used. The only sequela reported was urinary retention. Percutaneous cervical cordotomy used for the treatment of pelvisacral or predominantly unilateral perineal pain gave complete pain relief until death in 76.7% of patients, either alone (36.7%) or in conjunction with pharmacological therapy (40%). Analysis of the data enabled us to establish the respective indications for the two procedures and to identify those cases in which their use may be complementary.
D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000628:therapy; D002818:Cordotomy; D005260:Female; D005500:Follow-Up Studies; D005833:Genital Neoplasms, Female / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods; D010166:Palliative Care / Q000379:methods; D010386:Pelvic Neoplasms / Q000628:therapy*; D011677:Punctures; D012004:Rectal Neoplasms / Q000628:therapy; D013346:Subarachnoid Space; D001749:Urinary Bladder Neoplasms / Q000628:therapy