RNA concentration and protein synthesis in rat brain during development.
As a first approximation of ribosomal concentration we have measured total RNA in some regions of the CNS at different ages and found that the rates of protein synthesis therein are directly proportional to the RNA content. This suggests that the 'RNA activity' remains unchanged during growth and that higher protein synthesis rates in young brain are due to higher content of ribosomal material.
D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000378:metabolism; D001923:Brain Chemistry; D008099:Liver / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D010902:Pituitary Gland / Q000378:metabolism; D012313:RNA / Q000032:analysis*; D012335:RNA, Ribosomal / Q000378:metabolism; D051381:Rats
D009419:Nerve Tissue Proteins; D012335:RNA, Ribosomal; D012313:RNA