title: Substance P-immunoreactive nerves in the human cornea and iris.
abstract: Human corneas and irides obtained from corneal surgery or sector iridectomies were processed according to the indirect immunofluorescence technique for the demonstration of substance P (SP) immunofluorescence by means of a monoclonal SP antibody. SP immunofluorescence was observed in varicose fibers of the corneal epithelium and nerve trunks in the corneal stroma. SP-immunoreactive nerve fibers in the iris were detected mainly in the pupillary margin in both dilator and sphincter areas.
mesh_terms: D003315:Cornea / Q000276:immunology / Q000294:innervation*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007498:Iris / Q000276:immunology / Q000294:innervation*; D009412:Nerve Fibers / Q000032:analysis / Q000276:immunology*; D013373:Substance P / Q000032:analysis / Q000276:immunology
chemical_list: D013373:Substance P