Anaphylactic reaction to aprotinin despite negative ocular sensitivity tests.
A man with a history of pancreatitis was given aprotinin intravenously just before endoscopic retrograde pancreatography. Despite negative sensitivity tests with aprotinin eye drops he developed a profound anaphylactic reaction on intravenous administration of the drug. Ocular sensitivity tests may not predict severe anaphylactic reactions to intravenous aprotinin.
D000328:Adult; D000707:Anaphylaxis / Q000209:etiology*; D007611:Aprotinin / Q000008:administration & dosage / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D005123:Eye / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous; D008297:Male
D007611:Aprotinin