Failure to modify scrapie in mice by administration of interferon or anti-interferon globulin.
Administration of potent mouse interferon preparations or anti-mouse interferon globulin did not influence the evolution of scrapie in mice after intraperitoneal injection of the agent. We conclude that the interferon system is probably not involved in scrapie.
D000818:Animals; D007372:Interferons / Q000627:therapeutic use*; D051379:Mice; D011328:Prions / Q000187:drug effects / Q000472:pathogenicity*; D012608:Scrapie / Q000382:microbiology / Q000628:therapy*; D012756:Sheep
D011328:Prions; D007372:Interferons