Klebsiella pneumoniae in a nephrological department.
The repeated isolation of Klebsiella pneumoniae biotypes 16 and 17 from haemodialysis fluid in concentrations exceeding 10(4) cfu/ml led to an investigation of strains isolated from routine specimens of nephrological patients to elucidate whether the dialysate strains could be a source of infection. A total of 118 patient-isolates were identified over a 4-year period. Biotypes 16 and 17 accounted for only nine patient-isolates. The distribution pattern of biotypes among haemodialysis patients and other nephrological patients during a 2-year period, when K. pneumoniae colonized the dialysate, and during a succeeding 2-year period, when it had been eradicated from the dialysate, indicated that there was no epidemiological connection. The patient-isolates comprised 21 different biotypes. Biotype 36 (indole-positive) remained the predominant strain throughout the whole period studied.
D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000382:microbiology*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000150:complications / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D007710:Klebsiella Infections / Q000209:etiology / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000145:classification / Q000302:isolation & purification*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects