Anemia in male adolescents in Singapore.
Among 990 young male adolescents studied, only 7 were anemic. Three of the anemics had beta-thalassemia trait and 4 had probable alpha-thalassemia trait. Forty-six individuals with hemoglobinopathies were detected: 29 with probable alpha-thalassemia trait, 10 with beta-thalassemia trait and 7 with heterozygous HbE. Heterozygous alpha and beta-thalassemia occurred predominantly in Chinese while heterozygous HbE was found entirely in Malays. There were no cases of established iron deficiency anemia and only 1 had iron deficient erythropoiesis. Folate deficiency occurred only in 8 subjects with thalassemia traits, and no vitamin B12 deficiency was detected.
D000293:Adolescent; D005006:Ethnicity; D005319:Fetal Hemoglobin / Q000235:genetics; D005492:Folic Acid / Q000097:blood; D006580:Genetic Carrier Screening; D006443:Hemoglobin A2 / Q000235:genetics; D006446:Hemoglobin E / Q000235:genetics; D006447:Hemoglobin H / Q000235:genetics; D006452:Hemoglobinometry; D006801:Humans; D007501:Iron / Q000097:blood; D008297:Male; D012846:Singapore; D013789:Thalassemia / Q000097:blood / Q000235:genetics*; D014805:Vitamin B 12 / Q000097:blood
D006443:Hemoglobin A2; D006446:Hemoglobin E; D005319:Fetal Hemoglobin; D006447:Hemoglobin H; D005492:Folic Acid; D007501:Iron; D014805:Vitamin B 12