title: Cytofluorometric study of nuclear DNA in the epidermis of keratotic dermatoses.
abstract: The cell cycle duration of basal cells in the epidermis of keratotic dermatoses was investigated with cytofluorometric method. In normal epidermis, the relative time spent in each phase was 85.1% (G1), 13.1% (S) and 1.8% (G2 + M). The relative time in ichthyosis vulgaris epidermis was similar to that in normal epidermis. In the case of psoriasis and non-bullous congenital ichthyosiform erythroderma, the relative number of S phase cells was more than that in normal epidermis. In psoriatic epidermis, nuclear protein value was highest not only in G1 fraction of basal cells but in differentiating cells.
mesh_terms: D000293:Adolescent; D000328:Adult; D002467:Cell Nucleus / Q000032:analysis; D003584:Cytological Techniques; D004247:DNA / Q000032:analysis*; D004817:Epidermis / Q000032:analysis*; D005470:Fluorometry; D006801:Humans; D007057:Ichthyosis / Q000151:congenital / Q000378:metabolism*; D008214:Lymphocytes / Q000032:analysis; D008297:Male; D011565:Psoriasis / Q000378:metabolism*; D013194:Staining and Labeling
chemical_list: D004247:DNA