[Gomori-positive hypothalamo-hypophyseal neurosecretory system of rats adrenalectomized at different stages of postnatal ontogeny].
In rats adrenalectomized in the first month of postnatal life, fast accumulation of neurosecretory material in the external median eminence is observed, the content of the material remaining increased within the whole postoperative period (3 weeks). This is presumably due to underdevelopment of transports mechanisms in the external median eminence in young rats. In rats adrenalectomized during the second month of postnatal life, the amount of neurosecretory material in neurohemal regions decreases immediately after the operation, increasing at the 2nd and 3rd weeks after the latter. This pattern of changes is similar to that in adult rats. In young operated rats, nucleolar growth is retarded in the neurosecretory cells of the supraoptic and paraventricular nuclei, being accelerated in cells of the anterior commissural group. This fact indicates the increase in protein and polypeptide synthesis in the neurosecretory cells of this group and suggests that just these cells produce neurosecretory material which is accumulated in the external median eminence after adrenalectomy.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000375:Aging; D000818:Animals; D005260:Female; D006128:Growth; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D008297:Male; D009489:Neurosecretion; D051381:Rats; D011919:Rats, Inbred Strains; D013194:Staining and Labeling / Q000379:methods
Gomori-polozhitel'naia gipotalamo-gipofizarnaia neĭrosekretornaia sistema krys, adrenaléktomirovannykh na raznykh stadiiakh postnatal'nogo ontogeneza.