Gramicidin A induces lysolecithin to form bilayers.
Heat-induced association of Gramicidin A with lysolecithin micelles results in the formation of lipid bilayer structures. The capacity of the Gramicidin A peptide to transform the lysolecithin lipid structure from micelle to bilayer is considered in terms of molecular packing mechanisms and relevance to membrane processes in general. The resulting lipid-bilayer-packaged channel system has particular usefulness in characterizing channel structure and mechanism.
D055598:Chemical Phenomena; D002621:Chemistry; D005614:Freeze Fracturing; D006096:Gramicidin; D008051:Lipid Bilayers / Q000138:chemical synthesis*; D008244:Lysophosphatidylcholines; D008563:Membrane Lipids; D008565:Membrane Proteins; D013696:Temperature
D008051:Lipid Bilayers; D008244:Lysophosphatidylcholines; D008563:Membrane Lipids; D008565:Membrane Proteins; D006096:Gramicidin