Spontaneous peripheral chorioretinal neovascularisation in association with sickle cell anaemia.
Chorioretinal neovascularisation was noted in the midperipheral fundus of a young black girl with sickle cell anaemia. Rapid-sequence fluorescein angiography showed choroidally fed neovascularisation in the centre of a large black sunburst (chorioretinal scar). We suspect that a massive midperipheral retinal haemorrhage from the sickle cell disease caused the sunburst and altered Bruch's membrane, thus allowing the ingrowth of choroidally fed vessels.
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D002829:Choroid / Q000098:blood supply*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009389:Neovascularization, Pathologic / Q000175:diagnosis*; D012171:Retinal Vessels