[Characteristics of the action of an acidic sulfated polysaccharide on global blood coagulation in vitro. Preliminary study in various species of mammals and in man].
An acid sulphated polysaccharide, isolated from a red marine seaweed, Asparagopsis armata ( Harv .), increases the coagulation time of the plasma in vitro studies. This property, compared with the anticoagulant activity of pentosan polysulphate and heparin, pr esents , with concentration and temperature, some variations in man and other mammals . The rat and human plasma seem to behave in the same way with this substance.
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests; D001831:Body Temperature; D002417:Cattle; D006493:Heparin / Q000494:pharmacology; D006736:Horses; D006801:Humans; D066298:In Vitro Techniques; D010426:Pentosan Sulfuric Polyester / Q000494:pharmacology; D011134:Polysaccharides / Q000494:pharmacology*; D051381:Rats; D012756:Sheep; D013552:Swine
D011134:Polysaccharides; D010426:Pentosan Sulfuric Polyester; C028510:armatan; D006493:Heparin
Particularités de l'action d'un polysaccharide sulfaté acide sur la coagulation globale du sang in vitro. Etude préliminaire chez différentes espèces de Mammifères dont l'Homme.