New polyenic antibiotics active against gram-positive and -negative bacteria. I. Isolation and purification of antibiotics produced by Gluconobacter sp. W-315.
A new antibiotic, tentatively named as AB-315, was isolated from the fermentation broth of Gluconobacter sp. W-315. The antibiotic consists of a mixture of chemically related compounds. These compounds showed similar profiles in UV absorbancy. The antibiotics were active against Gram-positive and -negative bacteria, slightly active against fungi but not against yeasts.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D006801:Humans; D008970:Molecular Weight; D009374:Neoplasms, Experimental / Q000188:drug therapy; D009492:Neurospora crassa / Q000378:metabolism; D011548:Pseudomonadaceae / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic