title: Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA.
abstract: Antibodies raised in rabbits against deoxyguanylate and deoxycytidylate bind to 3H-lambda double stranded DNA and the binding is base specific. The concentrations of antibody populations that bind to double stranded DNA are much less than those binding to denatured DNA. Due to their low concentrations, these antibodies were not detected in earlier studies. These antibodies are expected to be useful to probe the conformational flexibilities of double stranded DNAs.
mesh_terms: D000906:Antibodies; D000936:Antigen-Antibody Complex; D010582:Bacteriophage lambda; D004277:DNA, Single-Stranded; D004279:DNA, Viral; D003843:Deoxycytidine Monophosphate / Q000276:immunology*; D003845:Deoxycytosine Nucleotides / Q000276:immunology*; D003848:Deoxyguanine Nucleotides / Q000276:immunology*; D006241:Haptens
chemical_list: D000906:Antibodies; D000936:Antigen-Antibody Complex; D004277:DNA, Single-Stranded; D004279:DNA, Viral; D003845:Deoxycytosine Nucleotides; D003848:Deoxyguanine Nucleotides; D006241:Haptens; D003843:Deoxycytidine Monophosphate