[Characteristics of bunyavirus- and togavirus-induced nonspecific suppressors inhibiting delayed hypersensitivity].
Some properties and mechanisms of action of nonspecific suppressor cells, inhibiting delayed hypersensitivity to sheep red blood cells and activated in vivo in experimental tick-borne encephalitis and Tahyna virus infections in mice, have been studied. These nonspecific suppressor cells have been identified as T-lymphocytes in experiments with the use of antisera to T- and B-lymphocytes. The function of the suppressor cells can be realized without their proliferation and is mediated by a soluble factor whose formation requires the synthesis of protein. In respect to hydrocortisone, the above-mentioned suppressor cells are subdivided into 2 subpopulations: hydrocortisone-resistant in the thymus and hydrocortisone-sensitive in the spleen.
D000818:Animals; D000961:Antilymphocyte Serum / Q000276:immunology; D002043:Bunyaviridae / Q000276:immunology*; D002141:Encephalitis Virus, California / Q000276:immunology*; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004670:Encephalitis, California / Q000276:immunology; D004675:Encephalitis, Tick-Borne / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007113:Immunity, Innate; D051379:Mice; D008808:Mice, Inbred CBA; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology*
D000961:Antilymphocyte Serum
Kharakteristika indutsiruemykh bun'ia- i togavirusami nespestsificheskikh supressorov, ugnetaiushchikh giperchuvstvitel'nosti zamedlennogo tipa.