title: Prolactin and luteinizing hormone levels of prelaying, laying and postlaying turkey hens following central administration of serotonin and peripheral administration of quipazine maleate.
abstract: The influence of serotonin (5-HT) on plasma prolactin and LH levels in female turkeys was studied by systemic injection of quipazine maleate, at 5-HT agonist, or by cerebroventricular injection of 5-HT itself. Within 30 min after injection, quipazine maleate (20 mg administered i.p.) elicited a significant increase in plasma prolactin in hens approaching sexual maturity as well as in laying hens. A 5-mg dose. had no effect on prolactin levels of either prelaying or laying hens. Intraventricular injection of 5 and 25 micrograms of 5-HT caused an increase in plasma prolactin of prelaying hens. A 5-micrograms dose of 5-HT was also effective in increasing prolactin levels in laying hens and in hens that had stopped laying due to ventricular cannula implantation. Neither quipazine maleate nor intraventricularly injected 5-HT had an effect on LH levels in any experiment.
mesh_terms: D000818:Animals; D005260:Female; D007276:Injections, Intraventricular; D007700:Kinetics; D007986:Luteinizing Hormone / Q000097:blood*; D010058:Oviposition; D011388:Prolactin / Q000097:blood*; D011804:Quinolines / Q000494:pharmacology*; D011814:Quipazine / Q000031:analogs & derivatives / Q000494:pharmacology*; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology*; D014422:Turkeys / Q000097:blood*
chemical_list: D011804:Quinolines; D012701:Serotonin; D011814:Quipazine; D011388:Prolactin; D007986:Luteinizing Hormone