[Recent aspects of selected autoantibodies in patients with systemic lupus erythematosus and their clinical relevance. II. Antibodies against histone, Sm, Ro and La].
Antigen-antibody systems (antigens: histone, Sm, Ro, La) are described. Aspects of diagnosis, differential diagnosis, and monitoring in SLE are especially considered. Their relevance in view of SLE-subclassification is discussed. Antibodies directed against histone and Sm, and--with some restriction--against Ro/La also are valuable tools in immunological characterization of SLE. Antibodies against La have only in association with anti-Ro-antibodies prognostic importance.
D000915:Antibody Affinity; D000941:Antigens / Q000276:immunology; D034961:Antigens, Nuclear; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001324:Autoantigens; D006657:Histones / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000276:immunology*; D009698:Nucleoproteins / Q000276:immunology; D011379:Prognosis; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear; D055517:snRNP Core Proteins; D000097585:SS-B Antigen; D000099207:SS-A Antigen
D000941:Antigens; D034961:Antigens, Nuclear; D001323:Autoantibodies; D001324:Autoantigens; D006657:Histones; D009698:Nucleoproteins; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear; D055517:snRNP Core Proteins; D000097585:SS-B Antigen; D000099207:SS-A Antigen; C116006:RO60 protein, human
Neuere Aspekte zu ausgewählten Autoantikörpern bei Patienten mit systemischem Lupus erythematodes und ihre klinische Bedeutung. II. Mitteilung: Antikörper gegen Histon, Sm, Ro und La.