[Effect of non-ionic roentgenocontrast preparation Omnipaque-350 on central hemodynamics and myocardial contraction].
The authors studied the effect of the non-ionic radiopaque substance Omnipaque-350 on the central hemodynamics and myocardial contractility. A comprehensive angiographic examination was conducted in 25 patients. Omnipaque-350, when administered intravascularly, was found to induce the same general reactions as ionic triiod-containing radiopaque. It did not exert direct myocardiodepressive effect; yet, upon intracoronary administration it caused uniform changes in myocardial contractility and elasticity which corresponded to transitory alterations in its perfusion. During left ventriculography, Omnipaque-350 as compared with Urografin-76, has less marked hypervolemic properties and a less significant impact on the central hemodynamics and the pump function of the heart.
D000293:Adolescent; D000328:Adult; D000790:Angiocardiography; D006332:Cardiomegaly / Q000000981:diagnostic imaging / Q000503:physiopathology; D002648:Child; D003287:Contrast Media / Q000494:pharmacology*; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007463:Iodobenzoates / Q000494:pharmacology*; D007472:Iohexol; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects*; D014283:Triiodobenzoic Acids / Q000494:pharmacology*
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol
Vliianie neionnogo rentgenokontrastnogo preparata Omnipak-350 na tsentral'nuiu gemodinamiku i sokratimost' miokarda.