[T-suppressors in experimental adjuvant arthritis and immunosuppression].
The functional activity of T-suppressors in experimental adjuvant arthritis in CBA and C57BL/6 mice, as well as after the injection of an immunosuppressive agent, has been studied. The successful development of experimental arthritis has been shown to occur simultaneously with essential disturbances (a decrease) in the function of T-suppressors. The injection of batriden, an immunosuppressive agent, into mice at the moment when adjuvant arthritis is induced in the animals leads to an even greater suppression of the function of T-suppressors. The degree to which this function is suppressed in experimental adjuvant arthritis depends on the genotype of mice.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D001168:Arthritis / Q000276:immunology*; D001169:Arthritis, Experimental / Q000276:immunology*; D006072:Gossypol / Q000031:analogs & derivatives*; D007108:Immune Tolerance / Q000187:drug effects; D007114:Immunization; D007166:Immunosuppressive Agents / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology*; D013997:Time Factors
D007166:Immunosuppressive Agents; C016259:batridene; D006072:Gossypol
T-supressory pri éksperimental'nom ad''iuvantnom artrite i immunosupressii.