Fructose 2,6-bisphosphate in livers of genetically obese rats.
Livers of genetically obese (fa/fa) rats, starved for 24 h, contained more fructose 2,6-bisphosphate, glucose 6-phosphate, fructose 6-phosphate and glycogen, and more pyruvate kinase and phosphofructokinase 2 activities, than livers of control lean rats. These changes may be explained in terms of cyclic AMP concentration, which was decreased in livers of obese starved rats.
D000818:Animals; D005635:Fructosediphosphates / Q000378:metabolism*; D006598:Hexosediphosphates / Q000378:metabolism*; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009765:Obesity / Q000378:metabolism*; D010732:Phosphofructokinase-1 / Q000378:metabolism; D011770:Pyruvate Kinase / Q000378:metabolism; D051381:Rats; D013217:Starvation / Q000378:metabolism; D013403:Sugar Phosphates / Q000378:metabolism
D005635:Fructosediphosphates; D006598:Hexosediphosphates; D008112:Liver Glycogen; D013403:Sugar Phosphates; C027652:fructose 2,6-diphosphate; D010732:Phosphofructokinase-1; D011770:Pyruvate Kinase