The problem of the sensitization to dithiocarbamates in thiuram-allergic patients.
Because of the occurrence of hand dermatitis in members of a surgical staff due to allergy to thiuram-containing rubber gloves, an investigation was performed about cross-sensitization between thiuram compounds and dithiocarbamates. Positive reactions to dithiocarbamates were compared with reactions to 8 brands of hypo-allergenic or dithiocarbamate-containing surgical gloves. There appeared to be a marked difference in reactions to the dithiocarbamate-containing gloves. Some brands gave negative or nearly always negative reactions, while other brands caused many positive reactions. Thiuram-allergic patients were advised to wear nonreacting rubber gloves or PVC gloves.
D000328:Adult; D000368:Aged; D003429:Cross Reactions; D009783:Dermatitis, Occupational / Q000209:etiology / Q000276:immunology*; D005260:Female; D005932:Gloves, Surgical; D006801:Humans; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D013859:Thiocarbamates / Q000009:adverse effects* / Q000276:immunology; D013893:Thiram / Q000009:adverse effects / Q000276:immunology
D013859:Thiocarbamates; D013893:Thiram