title: [Perthes' disease in scintigraphy - early diagnosis, course and therapeutic consequences].
abstract: A four year study on radionuclide imaging in Perthes's disease is reported. The results reveal that radionuclide imaging facilitates the earliest diagnosis possible as well as the differentiation against other affections of the hip. In eleven cases (diagnoses ascertained by X-ray follow up or biopsy) the duration of the course of Perthes' disease was shortened and the ultimate outcome was improved because of the early onset of therapy. Follow up examinations with radionuclide imaging and quantification of uptake reveal the extent of revascularisation of the necrosis of the femoral head and the epiphyseal plate at any point in time during the course of the disease. This leads to prognostic and therapeutic consequences, particularly in view of expected head at risk signs in the development of Perthes' disease.
mesh_terms: D000293:Adolescent; D002370:Casts, Surgical; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004164:Diphosphonates; D005260:Female; D005270:Femur Head / Q000000981:diagnostic imaging*; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging; D007873:Legg-Calve-Perthes Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D008297:Male; D011859:Radiography; D011877:Radionuclide Imaging; D013667:Technetium; D013669:Technetium Tc 99m Medronate; D013997:Time Factors
chemical_list: D004164:Diphosphonates; D013667:Technetium; D013669:Technetium Tc 99m Medronate
vernacular_title: Der Morbus Perthes in der Szintigraphie -- Frühdiagnose, Verlauf und therapeutische Konsequenzen.