Immune interferon (IFN-gamma) production in autologous mixed cultures.
T cells were exposed in vitro to autologous B cells or monocytes. Tested on the seventh day, the cultured lymphocytes lysed K562, Daudi, autologous, and allogeneic phytohemagglutinin (PHA) blasts. Autologous B blasts were not affected. The supernatants contained gamma interferon (IFN-gamma). The quantity of IFN did not correlate with the strength of the proliferative response nor with the strength of the cytotoxic potential.
D002455:Cell Division; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007371:Interferon-gamma / Q000032:analysis / Q000096:biosynthesis*; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology*
D007371:Interferon-gamma