title: "Cold spot" on bone scan at the site of primary osteosarcoma.
abstract: A 5-year-old girl presented with a rapidly growing osteosarcoma of the proximal right tibia. The radiographically osteoblastic lesions appeared as a "cold" on the 99mTc-MDP bone scan. Possible explanations for this unusual finding on the bone scan are discussed.
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D004164:Diphosphonates; D005260:Female; D006801:Humans; D012516:Osteosarcoma / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013667:Technetium; D013669:Technetium Tc 99m Medronate; D013977:Tibia / Q000000981:diagnostic imaging*
chemical_list: D004164:Diphosphonates; D013667:Technetium; D013669:Technetium Tc 99m Medronate