Surface receptors for IgG and complement on equine alveolar macrophages.
Isolated equine alveolar macrophages obtained by bronchopulmonary lavage of four live ponies demonstrated surface receptors for equine IgG, equine IgM, and complement-coated sheep red blood cells, but not equine IgM or complement-coated erythrocytes alone. In addition, demonstration of IgG receptors was found to depend on the level of erythrocyte sensitization and could not be demonstrated by red blood cell rosetting techniques at low levels of sensitization. Demonstration of receptors for equine complement by red cell rosetting techniques required the presence of both IgM antibody and serum derived (complement) components. This is the first such study of receptors on equine alveolar macrophages.
D000818:Animals; D004912:Erythrocytes / Q000276:immunology; D006736:Horses; D007075:Immunoglobulin M / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D011650:Pulmonary Alveoli / Q000276:immunology*; D011951:Receptors, Complement / Q000276:immunology*; D017452:Receptors, IgG; D011971:Receptors, Immunologic / Q000276:immunology*; D012397:Rosette Formation; D012756:Sheep
D007075:Immunoglobulin M; D011951:Receptors, Complement; D017452:Receptors, IgG; D011971:Receptors, Immunologic