title: External and biopsy determination of preoperative Tc-99m MDP femoral-head labeling in fracture of the femoral neck: concise communication.
abstract: In 30 fresh fractures of the femoral neck, the preoperative femoral-head tracer uptake in Tc-99m MDP scintimetry was compared with the uptake of peroperatively obtained femoral-head biopsies and correlated to intravital bone staining by tetracycline, infused concurrently. Bone uptakes of Tc-99m MDP and tetracycline were shown to correlate well. Total absence of Tc-99m MDP uptake in the femoral-head biopsy corresponded to a scintigraphic uptake ratio of 0.7 (fractured over contralateral head), whereas a normal Tc-99m MDP biopsy uptake corresponded to a ratio of 1.5. This suggests that in Tc-99m MDP scintimetry of a normal hip, less than half of the emission ascribed to the femoral head is derived from the femoral head itself.
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D004164:Diphosphonates; D005260:Female; D005265:Femoral Neck Fractures / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005270:Femur Head / Q000473:pathology; D005271:Femur Head Necrosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010118:Oxytetracycline; D011877:Radionuclide Imaging; D013667:Technetium; D013669:Technetium Tc 99m Medronate
chemical_list: D004164:Diphosphonates; D013667:Technetium; D010118:Oxytetracycline; D013669:Technetium Tc 99m Medronate