title: Postoperative pathology of congenital heart disease. I. Complete atrio-ventricular canal.
abstract: The postoperative pathology observed in 17 patients with complete atrioventricular canal, who died following total correction is described. In 3 patients, in whom valve replacement was necessary, the death was due to late prosthetic dysfunction. Out of 14 patients who underwent plastic repair, 4 died from undetected residual cardiac anomalies, which in 2 cases were associated with pulmonary obstructive vascular disease, 3 from unexplained myocardial infarction, 3 from inadequate postoperative care and 4 from pulmonary obstructive vascular disease which presented as an isolated finding. An analysis of the incidence of pulmonary obstructive vascular disease in these patients disclosed that it can develop before one year of age in some patients with Down syndrome.
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D009206:Myocardium / Q000473:pathology; D011660:Pulmonary Heart Disease / Q000209:etiology / Q000473:pathology