[Present status of primary Gougerot-Sjögren syndrome].
When primary and not part of a systemic autoimmune disease, Sjögren's syndrome has peculiar clinical, serological and genetic features. It exceptionally becomes malignant but evolves to a stage of pseudo-lymphoma. Numerous studies suggest hyperstimulation of B-lymphocytes that would result from destruction of suppressive T-lymphocytes, this destruction in turn being probably due to failure of immune complex clearing by the reticulo-endothelial system.
D000974:Antibodies, Antinuclear / Q000032:analysis; D000936:Antigen-Antibody Complex / Q000378:metabolism; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D008223:Lymphoma / Q000209:etiology; D012157:Mononuclear Phagocyte System / Q000276:immunology; D011230:Precancerous Conditions; D012859:Sjogren's Syndrome / Q000175:diagnosis / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000974:Antibodies, Antinuclear; D000936:Antigen-Antibody Complex
Actualité du syndrome de Gougerot-Sjögren primitif.