Bactericidal activity of norfloxacin and nine other urinary tract antibiotics against Gram-negative bacilli causing bacteriuria in chronically catheterized patients.
We compared the bactericidal activities of norfloxacin and nine other oral urinary tract antibiotics against 344 Gram-negative bacilli causing bacteriuria in chronically catheterized patients. Norfloxacin killed all organisms at 32 mg/l, 91% of isolates at 2 mg/l, and was the most active antibiotic tested.
D000892:Anti-Infective Agents, Urinary / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001437:Bacteriuria / Q000382:microbiology*; D002404:Catheterization; D002937:Cinoxacin / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D009643:Norfloxacin
D000892:Anti-Infective Agents, Urinary; D009268:Nalidixic Acid; D002937:Cinoxacin; D009643:Norfloxacin