A study of T suppressor activity after bacterial immunotherapy.
T suppressor cell activity from twenty non-atopic patients with bronchial asthma of bacterial etiology, were studied. The patient's ages ranged from 14 to 60 years with a mean age of 40 years. Seven patients were male and thirteen were female. As control subjects six healthy young adults were studied. The patients were divided in two groups: one including patients with less than one year of bacterial immunotherapy and another, including patients with one to four years of immunotherapy. The method described in other works was followed. The results obtained in these two groups were compared to those obtained in a group of healthy volunteers and were analyzed on the basis of statistical data using the student's t test. In patients with bacterial asthma, we observed normal suppressor cell activity, similar to that of subjects undergoing immunotherapy. As such, bacterial immunotherapy does not seem to objectively affect the regulatory mechanisms of cellular immunity.
D000293:Adolescent; D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology*; D001249:Asthma / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D003208:Concanavalin A / Q000494:pharmacology; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D008875:Middle Aged; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D000942:Antigens, Bacterial; D003208:Concanavalin A