[Role of T-, B-, null, suppressor lymphocytes and anti-brain antibodies in infectious-allergic disease of the nervous system].
Clinicoimmunologic studies involving 255 patients with infectious and allergic nervous disorders showed some alterations in their immune homeostasis in association with a certain imbalance in B-cell immunity. These changes were expressed in a decrease in the functional activity and absolute content of T-lymphocytes in the peripheral blood, in a steady increase in O-cells, and in insufficient lymphocyte T-suppressory control. The importance of elevated brain antibody levels for making the differential diagnosis of the autoallergic process in the nerve tissues is demonstrated.
D000328:Adult; D001323:Autoantibodies; D001402:B-Lymphocytes / Q000276:immunology; D001921:Brain / Q000276:immunology*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D008211:Lymphocyte Cooperation; D008214:Lymphocytes / Q000276:immunology*; D008215:Lymphocytes, Null / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D001323:Autoantibodies
Rol' T-, B-, nulevykh, suppressornykh limfotsitov i protivomozgovykh antitel pri infektsionno-allergicheskikh zabolevaniiakh nervnoĭ sistemy.