title: Physiological and pathological influences of central nervous system on the immune system: a critical appraisal.
abstract: There is considerable evidence of intricate links between central nervous and immune systems. This paper makes a critical assessment of these relationships. Recent experimental data on hypothalamic influences on Natural Killer activity in mice have been presented and the problems met with in defining causal nexuses discussed. Some information on immune reactivity in patients with mental disorders has briefly been reviewed.
mesh_terms: D000818:Animals; D001921:Brain / Q000276:immunology*; D006801:Humans; D007031:Hypothalamus / Q000276:immunology; D007372:Interferons / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology; D008223:Lymphoma / Q000276:immunology; D008297:Male; D001523:Mental Disorders / Q000150:complications; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009369:Neoplasms / Q000150:complications / Q000276:immunology; D051381:Rats; D012559:Schizophrenia / Q000276:immunology; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D007372:Interferons