Morphological aspects of the rat kidney preserved by cold storage. II. The juxtaglomerular apparatus.
The present paper reports on the changes occurring in the juxtaglomerular apparatus during preservation of the rat kidney by cold storage, using two media: Sacks and Plasmagel, to which a membrane stabilizing "cocktail" was added (hydrocortisone, chlorpromazine, epsilonaminocaproic acid - EACA, propranolol). Evident alterations appeared at 48 hours more accentuated at 72 and 96 hours, and more intense when preserved in Plasmagel. The most affected structure in the juxtaglomerular apparatus was the macula densa, the epithelial cells having a more stable structure.
D015119:Aminocaproic Acid / Q000494:pharmacology; D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology; D006854:Hydrocortisone / Q000494:pharmacology; D007606:Juxtaglomerular Apparatus / Q000033:anatomy & histology*; D007668:Kidney; D009926:Organ Preservation; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D012034:Refrigeration; D014021:Tissue Preservation
D011433:Propranolol; D002746:Chlorpromazine; D015119:Aminocaproic Acid; D006854:Hydrocortisone