A monoclonal antibody (HNo-g7) with specificity for a human nucleolar protein.
A murine monoclonal antibody which reacts strongly with the nucleoli of human epithelial cells has been isolated. The antibody is of the IgM class and the antigen has a molecular weight of 45 000. The antibody appears to react with interphase chromatin only and to have specificity for epithelial cells.
D000911:Antibodies, Monoclonal; D002466:Cell Nucleolus / Q000032:analysis*; D002843:Chromatin / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006367:HeLa Cells / Q000032:analysis / Q000166:cytology; D006801:Humans; D007075:Immunoglobulin M; D008970:Molecular Weight; D009698:Nucleoproteins / Q000032:analysis*
D000911:Antibodies, Monoclonal; D002843:Chromatin; D000939:Epitopes; D007075:Immunoglobulin M; D009698:Nucleoproteins