PPNG conjunctivitis.
The treatment regimen for penicillin sensitive gonococcal conjunctivitis in an adult normally includes parenteral penicillin, frequent ocular irrigation, and topical ophthalmic gentamicin or tetracycline ointment. However, if a conjunctivitis is caused by a beta-lactamase producing microbe such as PPNG, then different antibiotics are required: e.g., spectinomycin or cefoxitin parenterally and topical chloramphenicol. Also, whereas urethritis is frequently treated with singular injections of penicillin or spectinomycin HCI (Trobicin), cases of PPNG ocular infections require a much longer course of treatment often involving seven days of intramuscular or intravenous antibiotics.
D000328:Adult; D002440:Cefoxitin / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D003231:Conjunctivitis / Q000188:drug therapy / Q000209:etiology*; D006069:Gonorrhea / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D010403:Penicillin Resistance; D000198:Spectinomycin / Q000627:therapeutic use
D002701:Chloramphenicol; D002440:Cefoxitin; D000198:Spectinomycin