title: [Phosphohexose isomerase in psoriasis].
abstract: --The authors study in psoriasis an enzyme of the glucolytic way, the Phospho-hexose-isomerase. --They find significant high levels in blood and damaged skin, while these were "normal" in healthy skin. --Phospho-hexose-isomerase acts as a biological marker in psoriasis, and acquires the significance of an active cellular proliferation. --The highest values are those of the erythrodermaes which become normal with clinical involution. --The authors suggest that psoriasis, by an exaggerated cellular division inhibition mechanism, metabolism is deviated in order to bring the energetic elements and substrate to form the new cell. --Phospho-hexose-isomerase is not specific of the malignant process.
mesh_terms: D000293:Adolescent; D002455:Cell Division; D005260:Female; D005956:Glucose-6-Phosphate Isomerase / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010732:Phosphofructokinase-1 / Q000032:analysis; D011565:Psoriasis / Q000201:enzymology* / Q000473:pathology; D012867:Skin / Q000201:enzymology
chemical_list: D010732:Phosphofructokinase-1; D005956:Glucose-6-Phosphate Isomerase
vernacular_title: La fosfohexosaisomerasa en la psoriasis.