Diabetic nephropathy with superimposed immune complex glomerulonephritis.
We describe six diabetic patients with superimposed immune complex glomerulonephritis. Renal manifestations included sudden change in renal function with hematuria in three patients and massive proteinuria in the other three. Renal histology showed the characteristic changes of diabetic nephropathy along with those of immune complex glomerulonephritis. Biopsy revealed the explanation for the sudden renal changes, thus emphasizing its importance in management of these patients.
D000328:Adult; D001485:Basement Membrane / Q000648:ultrastructure; D001706:Biopsy; D003928:Diabetic Nephropathies / Q000150:complications* / Q000473:pathology; D005260:Female; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007105:Immune Complex Diseases / Q000150:complications* / Q000473:pathology; D007678:Kidney Glomerulus / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011507:Proteinuria / Q000209:etiology