Recovery of norfloxacin in feces after administration of a single oral dose to human volunteers.
Twelve healthy volunteers received single 400-mg oral doses of norfloxacin. During the ensuing 48 h, from 8.3 to 53.3% (mean, 28%) of this dose was recovered in the feces. Peak drug concentrations in fecal specimens ranged from 207 to 2,716 micrograms/g.
D000328:Adult; D005243:Feces / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009268:Nalidixic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D009643:Norfloxacin; D013997:Time Factors
D009268:Nalidixic Acid; D009643:Norfloxacin