Anticholinergic drugs in airways obstruction.
This paper reviews briefly the place of ipratropium bromide in the treatment of airways obstruction. Oxitropium bromide, a new quaternary ammonium compound derived from scopolamine was shown to be as effective a bronchodilator in a dose of 200 micrograms by inhalation as ipratropium bromide 80 micrograms in 20 patients with atopic asthma.
D001249:Asthma / Q000188:drug therapy*; D001286:Atropine Derivatives / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use*; D010276:Parasympatholytics / Q000627:therapeutic use; D010366:Peak Expiratory Flow Rate; D012602:Scopolamine Derivatives / Q000627:therapeutic use
D001286:Atropine Derivatives; D010276:Parasympatholytics; D012602:Scopolamine Derivatives; C017590:oxitropium; D009241:Ipratropium