An in vitro study of lymphocytes in patients with atopic dermatitis.
The authors studied the T- and B-lymphocyte sub-populations, the stimulation of the lymphocytes with phytohaemagglutinin and pokeweed mitogen, the non-specific T suppressor activity and the amounts of serum IgE in a group of thirty-four patients with atopic dermatitis. Comparison with a group of 100 healthy controls revealed a diminution in the T sub-population, an increase in the B sub-population, no change in the response index to stimulation with phytohaemagglutinin or pokeweed mitogen, a diminished T-suppressor activity and an increase in the level of serum IgE.
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D003208:Concanavalin A / Q000494:pharmacology; D003876:Dermatitis, Atopic / Q000276:immunology*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D010835:Phytohemagglutinins / Q000494:pharmacology; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D010835:Phytohemagglutinins; D003208:Concanavalin A