title: Immunoreactive copper-zinc superoxide-dismutase (SOD-1) in mosaic trisomy 21 and normal subjects.
abstract: Copper-zinc superoxide-dismutase (SOD-1) (E.C. 1.15.11) levels were measured in 9 children with mosaic trisomy 21 as identified by R, H, G-banding technics. Radioimmunoassay of erythrocytes and fibroblasts did not demonstrate any significant correlation between levels of SOD-1 and percentage of trisomic 21 cells in the two target cell populations studied.
mesh_terms: D004314:Down Syndrome / Q000201:enzymology* / Q000235:genetics; D004912:Erythrocytes / Q000201:enzymology; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D009030:Mosaicism; D011863:Radioimmunoassay; D013482:Superoxide Dismutase / Q000097:blood* / Q000276:immunology
chemical_list: D013482:Superoxide Dismutase