[Nicotinic acid metabolism in patients with non-coronarogenic heart diseases].
To study the supply with nicotinic acid, 74 patients with rheumatic fever of varying degree and circulatory disorders, 10 patients with infectious-allergic myocarditis, 15 with tonsilogenous myocardiodystrophy were examined. Seventy normal subjects served as control. The supply with vitamin PP was evaluated from the blood content of NAD, NADP and N'-methylnicotinamide and its excretion with urine. All the patients with myocarditis and rheumatic fever demonstrated a decrease in the nicotinic acid supply which became more marked as the degree of rheumatic fever rose and circulatory failure supervened. In patients with tonsilogenous myocardiodystrophy , the disturbance of the vitamin supply was less overt.
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000378:metabolism*; D009243:NAD / Q000097:blood; D009249:NADP / Q000097:blood; D009536:Niacinamide / Q000031:analogs & derivatives / Q000378:metabolism; D009539:Nicotinic Acids / Q000172:deficiency / Q000378:metabolism*; D012214:Rheumatic Heart Disease / Q000378:metabolism*; D014069:Tonsillitis / Q000150:complications
D009539:Nicotinic Acids; D009243:NAD; D009536:Niacinamide; D009249:NADP; C008472:N-methylnicotinamide
Obespechennost' nikotinovoĭ kislotoĭ bol'nykh s nekoronarogennymi zabolevaniiami serdtsa.