title: Correlation of oligomycin-sensitive ATPase activity in trypanosomes with their content of an antigen to primary biliary cirrhosis.
abstract: The amounts of an antigen to primary biliary cirrhosis (PBC) which occur in subcellular fractions of Trypanosoma rhodesiense and T. lewisi correlate positively with the oligomycin-sensitive (OS) ATPase activity of these fractions. This result is consistent with the mitochondrial ATPase association of the antigen in mammalian and other cells. Higher levels of OS-ATPase and of PBC antigen in T. lewisi accord with a more extensive mitochondrial development in this species.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D000941:Antigens / Q000032:analysis*; D008105:Liver Cirrhosis, Biliary / Q000276:immunology*; D008930:Mitochondria, Liver / Q000276:immunology; D009840:Oligomycins / Q000494:pharmacology; D014345:Trypanosoma / Q000201:enzymology* / Q000276:immunology; D014350:Trypanosoma lewisi / Q000201:enzymology / Q000276:immunology
chemical_list: D000941:Antigens; D009840:Oligomycins; D000251:Adenosine Triphosphatases