Hexokinase isoenzymes: antigenic cross-reactivities and amino acid compositional relatedness.
Previously undetected antigenic cross-reactivities have been demonstrated between yeast and rat hexokinase isoenzymes using an enzyme-linked immune sorbent assay. The levels of structural homology between the isoenzymes have been assessed in terms of their relative antigenic cross-reactivities and their amino acid compositional relatedness. The three major rat hexokinases appear, despite their differing molecular sizes, to have a close evolutionary background and to share a common but distant ancestry with yeast and wheat-germ forms.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000936:Antigen-Antibody Complex; D002417:Cattle; D002918:Chymotrypsin / Q000032:analysis; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis*; D006593:Hexokinase / Q000032:analysis*; D006801:Humans; D007106:Immune Sera; D007124:Immunoenzyme Techniques; D007527:Isoenzymes / Q000032:analysis*; D051381:Rats; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D012709:Serum Albumin / Q000032:analysis; D013045:Species Specificity; D013552:Swine; D014357:Trypsin / Q000032:analysis
D000596:Amino Acids; D000936:Antigen-Antibody Complex; D000939:Epitopes; D007106:Immune Sera; D007527:Isoenzymes; D012709:Serum Albumin; D006593:Hexokinase; D002918:Chymotrypsin; D014357:Trypsin