title: Brief clinical report: prune belly syndrome: observations supporting the hypothesis of abdominal overdistention.
abstract: We report on an infant with the prune belly syndrome who was unusual in that the typical manifestations of the disorder were accompanied by an anterior abdominal wall defect. We speculate that this defect may have occurred as a result of splitting of the abdominal wall secondary to massive bladder dilatation and stretching of the abdominal muscles. An alternative explanation is that the defect may have been the result of secondary pressure necrosis from stretching forces or from contact with another structure, such as the cervix. This case lends further support to the hypothesis that bladder distention with overdistention of the abdomen may be the primary event leading to the findings observed in the prune belly syndrome.
mesh_terms: D000009:Abdominal Muscles / Q000002:abnormalities* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011535:Prune Belly Syndrome / Q000209:etiology* / Q000601:surgery; D001743:Urinary Bladder / Q000002:abnormalities*; D014547:Urinary Diversion