title: [Combination aerosol for bronchial asthma in childhood].
abstract: 40 children with clinical diagnosis of bronchial asthma aged 8--14 years, 39 with allergic disposition, were investigated. Acute therapeutic and protective effect on frequency of asthmatic attacks, pulmonary auscultation and lung function (FEV1, PF, FVC) by application of Fenoterol and Ipratropium as combination aerosol were registered. Over a period of 4 weeks we could reduce the frequency of attacks nearly to the half. 10 and 20 minutes after aerosol application we showed a good improvement of pulmonary ventilation. Only on children with severe asthma bronchiale an exclusive treatment with Berodual seems to be of modest protective effect.
mesh_terms: D000293:Adolescent; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001286:Atropine Derivatives / Q000627:therapeutic use*; D002648:Child; D004338:Drug Combinations / Q000627:therapeutic use; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use*; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use*; D008297:Male; D012119:Respiration
chemical_list: D000336:Aerosols; D001286:Atropine Derivatives; D004338:Drug Combinations; D004983:Ethanolamines; C030809:fenoterol, ipratropium drug combination; D005280:Fenoterol; D009241:Ipratropium
vernacular_title: Kombinationsaerosol beim Asthma bronchiale im Kindesalter.