Systemic contact dermatitis from Orinase and Diabinese in diabetics with para-amino hypersensitivity.
Diabetic patients sensitized by topical medication containing such para-amino compounds as sulfanilamide and benzocaine can acquire a widespread eczematous "systemic" contact dermatitis from the oral administration of such para-amino hypoglycemic drugs as Orinase or Diabinese.
D000328:Adult; D001566:Benzocaine / Q000009:adverse effects; D002747:Chlorpropamide / Q000009:adverse effects*; D048909:Diabetes Complications; D003875:Drug Eruptions / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013424:Sulfanilamides / Q000009:adverse effects; D014044:Tolbutamide / Q000009:adverse effects*
D013424:Sulfanilamides; D014044:Tolbutamide; D001566:Benzocaine; D002747:Chlorpropamide