title: [Red pigment dyes and acne. Clinical observations and experimental investigations (author's transl)].
abstract: Acne-like changes were observed on a child's cheeks after colouring them with a red felt-tip pen. Numerous comedos appeared around a red tattoo coloured with felt-tip pen ink on a 16 year old girl. In animal experiments using rabbits' ears, two organic pigment inks found in these types of felt-tip pens could be proved to be the cause of a comedo-producing reaction. We are concerned here with quinacridone dye, pigment violet 19 (C.I.46.500), and the chlorine containing azo dye, pigment red 7 (C.I. 12.420).
mesh_terms: D000152:Acne Vulgaris / Q000139:chemically induced* / Q000473:pathology; D000293:Adolescent; D000818:Animals; D001391:Azo Compounds / Q000009:adverse effects; D002648:Child; D004396:Coloring Agents / Q000009:adverse effects*; D005260:Female; D005542:Forearm; D006801:Humans; D011817:Rabbits; D013653:Tattooing / Q000009:adverse effects*
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents
vernacular_title: Rote Pigmentfarben und Akne. Klinische Beobachtungen und experimentelle Untersuchungen.