Endogenous prostaglandin E2 enhances polyclonal immunoglobulin production by tonically inhibiting T suppressor cell activity.
D000328:Adult; D000368:Aged; D000917:Antibody Formation / Q000187:drug effects*; D000954:Antigens, Surface / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D002999:Clone Cells / Q000276:immunology*; D015232:Dinoprostone; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects; D007213:Indomethacin / Q000494:pharmacology; D009000:Monocytes / Q000276:immunology; D011043:Pokeweed Mitogens / Q000276:immunology; D011458:Prostaglandins E / Q000494:pharmacology*; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects*
D000954:Antigens, Surface; D011043:Pokeweed Mitogens; D011458:Prostaglandins E; D015232:Dinoprostone; D007213:Indomethacin