title: [Zollinger-Ellison syndrome. Therapeutic aspects].
abstract: This review considers the place of surgery with its two indications: 1) suppression of the target organ of gastrin hypersecretion (total gastrectomy or other surgical procedures on the stomach), 2) radical tumour excision. The authors also discuss the use of anti-secretory drugs currently used in the Zollinger-Ellison syndrome and the respective usefulness of these different techniques in acute and chronic Zollinger-Ellison syndromes. The role of anti-tumour chemotherapy is also discussed.
mesh_terms: D002927:Cimetidine / Q000627:therapeutic use; D005743:Gastrectomy; D006801:Humans; D013311:Streptozocin / Q000627:therapeutic use; D015043:Zollinger-Ellison Syndrome / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D013311:Streptozocin; D002927:Cimetidine
vernacular_title: Syndrome de Zollinger-Ellison. Aspects thérapeutiques.