title: Effect of mercuric chloride on the intestinal absorption of an amino acid, glycine, in the freshwater murrel, Channa punctatus.
abstract: The effect of five concentrations of mercuric chloride (10 mM, 1 mM, 0.1 mM, 0.01 mM, 0.001 mM) on the rate of absorption of the amino acid glycine by the intestine of the freshwater murrel Channa punctatus has been studied. Intestinal absorption of glycine was also studied in fish exposed to a sublethal concentration (3 micrograms/l) of mercuric chloride for 15 and 30 days. The results revealed that all the five concentrations of mercuric chloride reduced the rate of absorption of glycine by the intestine. Maximum decrease was recorded with 10 mM of mercuric chloride in the instilled medium. The reduction in glycine transport was insignificant with 0.01 and 0.001 mM of mercuric chloride. In fish exposed to mercuric chloride by bath also, decrease in the rate of absorption of glycine was noted but it was significant only after 30 days of exposure.
mesh_terms: D000818:Animals; D005399:Fishes / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D007408:Intestinal Absorption / Q000187:drug effects*; D008627:Mercuric Chloride; D008628:Mercury / Q000494:pharmacology*
chemical_list: D008627:Mercuric Chloride; D008628:Mercury; D005998:Glycine