title: Efficacy of lincomycin-spectinomycin water medication on Mycoplasma meleagridis airsacculitis in commercially reared turkey poults.
abstract: A field trial was conducted to compare the efficacy of a combination of the drugs lincomycin and spectinomycin (LS) with Tylan (tylosin, T) against Mycoplasma meleagridis (MM) airsacculitis in 50,320 commercially reared turkey poults in Ohio. Both drugs were administered at 2 g per gallon of drinking water for the first 5 days of life. The poults were allotted randomly to two treatment groups with 8 or 5 replicates each. Initially, 250 poults were weighed, necropsied, and examined microbiologically and grossly for airsacculitis. At 3 weeks of age, 33 poults from each replicate were randomly selected, necropsied, and examined for airsacculitis. The data indicate that LS is superior to T as an aid in the control of MM airsacculitis in poults, as reflected by fewer air-sac lesions and greater improvement in weight gain (P less than 0.05).
mesh_terms: D000400:Air Sacs / Q000382:microbiology*; D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D007933:Leucomycins / Q000627:therapeutic use*; D008034:Lincomycin / Q000627:therapeutic use*; D008297:Male; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D011201:Poultry Diseases / Q000188:drug therapy* / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary; D000198:Spectinomycin / Q000627:therapeutic use*; D014422:Turkeys / Q000382:microbiology*
chemical_list: D004338:Drug Combinations; D007933:Leucomycins; D000198:Spectinomycin; D008034:Lincomycin