[Effect of prolonged hypokinesia on the growth and skeletal musculature in the rat].
Hypokinesia lasting for 1-5.5 months does not produce any muscular atrophy, but results in ceasing their growth and the growth of the animal. In the muscles, besides the soleus muscle, not any essential structural changes occur. The changes in the soleus muscle are manifested as a focal sclerosis and formation of new muscle fibers. They are considered as a result of a disturbed hemodynamics in it, that occurs during the first days of hypokinesia. During the readaptation period the animals and their muscles begin to grow again. A suggestion is expressed that one of the pathogenic causes making the growth stop is the stress that decreases the somatotrophic function of the hypophysis.
D000222:Adaptation, Physiological; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001835:Body Weight; D006128:Growth; D008297:Male; D009132:Muscles / Q000378:metabolism / Q000503:physiopathology*; D010088:Oxidoreductases / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000503:physiopathology*
D010088:Oxidoreductases; D000251:Adenosine Triphosphatases
Vliianie dlitel'noĭ gipokinezii na rost i skeletnuiu muskulaturu krys.