A synthetic crown ether carboxylic acid ionophore displays synergistic transport of Pr3+ in conjunction with lasalocid.
Transport of Pr3+ across phosphatidyl choline vesicles, as monitored by 31P nmr, is second-order in the crown ether carboxylic acid 2, as it is with respect to lasalocid (X-537 A). When the synthetic (2) and the natural (lasalocid) ionophores are incorporated together in approximately 3:1 ratio into the lipidic phase, the transport velocity is markedly enhanced.
D000818:Animals; D001692:Biological Transport; D002264:Carboxylic Acids; D002645:Chickens; D004530:Egg Yolk; D004988:Ethers, Cyclic; D005260:Female; D007476:Ionophores; D007832:Lasalocid; D008051:Lipid Bilayers; D008954:Models, Biological; D010713:Phosphatidylcholines; D011221:Praseodymium; D013329:Structure-Activity Relationship
D002264:Carboxylic Acids; D004988:Ethers, Cyclic; D007476:Ionophores; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D011221:Praseodymium; D007832:Lasalocid