[Effect of divalent cations on the properties of NaCl-stimulated ATPase activity in the mucosa of the rabbit small intestine].
The effect of bivalent cations on NaCl-stimulated ATPase activity in rabbit small intestinal mucosa was studied. Unlike Ba2+ and Zn2+, Ca2+ and Mg2+ added to the incubation medium at a concentration of 0.25 mM completely change ATPase activity. Histamine considerably reduces the inhibitory effect of Ca2+ and Mg2+ on NaCl-stimulated and oligomycin-inhibited ATPase activity. Possible mechanisms of the enzyme activity control in the cell are discussed.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D002413:Cations, Divalent / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004492:Edetic Acid / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology; D007413:Intestinal Mucosa / Q000187:drug effects / Q000201:enzymology*; D007421:Intestine, Small / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D009840:Oligomycins / Q000494:pharmacology; D011817:Rabbits; D012965:Sodium Chloride / Q000494:pharmacology*
D002413:Cations, Divalent; D009840:Oligomycins; D012965:Sodium Chloride; D006632:Histamine; D004492:Edetic Acid; D000251:Adenosine Triphosphatases
Vliianie dvukhvalentnykh kationov na svoĭstva NaCl-stimuliruemoĭ ATF-aznoĭ aktivnosti v slizistoĭ obolochke tonkoĭ kishki krolikov.