[Investigations of the influence of sodium salicylate on the gastric mucosa of the rat (author's transl)].
1. The investigation of the influence of sodium salicylate in therapeutic doses (100 mg/body weight/day) on the gastric mucosa of 60 rats revealed at the acute phase of the experiment morphological lesions of the superficial epithelium in term of an acute gastritis. At this stage neutral and acid mucopolysaccharides of gastric mucus were reduced. 2. Contrary to this, in long-term experiments epithelial changes and reduction of the mucous content of the cells were no longer detectable.
D000818:Animals; D005750:Gastric Juice / Q000032:analysis / Q000502:physiology; D005753:Gastric Mucosa / Q000187:drug effects*; D005756:Gastritis / Q000139:chemically induced*; D006023:Glycoproteins / Q000032:analysis; D006025:Glycosaminoglycans / Q000032:analysis; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012980:Sodium Salicylate / Q000494:pharmacology*; D013997:Time Factors
D006023:Glycoproteins; D006025:Glycosaminoglycans; D012980:Sodium Salicylate
Tierexperimentelle Untersuchungen über den Einfluss von natrium-salizylat auf die Magenschleimhaut der Ratte.