[Effects of 5023 SE on experimental cerebral ischemia in gerbils].
Unilateral ligation of the common carotid artery of gerbils results in cerebral edema and ipsilateral hemiparesia ending in death. The clinical symptoms of this experimental ischaemia can be quantified. Comparison of untreated gerbils and gerbils treated with Duxil showed that the drug reduces the neuropathological symptoms and cerebral edema induced by ischaemia and improves the vital prognosis in these animals.
D015765:Almitrine; D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy*; D004195:Disease Models, Animal; D004338:Drug Combinations / Q000627:therapeutic use; D005849:Gerbillinae; D010879:Piperazines / Q000627:therapeutic use*; D013997:Time Factors; D015016:Yohimbine / Q000627:therapeutic use*
D004338:Drug Combinations; D010879:Piperazines; D015016:Yohimbine; C037558:almitrine, raubasine drug combination; D015765:Almitrine
Effets du 5023 SE sur l'ischémie cérébrale expérimentale chez la gerbille.