Activation of Neurospora crassa soluble adenylate cyclase by calmodulin.
The soluble form of adenylate cyclase was extracted and purified from wild-type Neurospora crassa mycelia. Brain or N. crassa calmodulin significantly enhanced this enzyme activity in assay mixtures containing Mg2+-ATP as substrate. EGTA reverses this calmodulin activation.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D002147:Calmodulin / Q000494:pharmacology*; D004533:Egtazic Acid / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D009491:Neurospora / Q000201:enzymology*; D009492:Neurospora crassa / Q000187:drug effects / Q000201:enzymology*
D002147:Calmodulin; D004533:Egtazic Acid; D000262:Adenylyl Cyclases