In situ identification of mononuclear cells in lichen planus.
In this study, the in situ immunological typing of cell populations in lichen planus was attempted. T lymphocytes and suppressor/cytotoxic subsets, B lymphocytes, macrophages, immunocytes and Langerhans' cells were studied by one or more technical parameters and semiquantitative assessment of T cell populations were carried out. A critical evaluation of assays for T cell characterization was also attempted. T cells were found predominant in lichen planus infiltrate but macrophages were also many. Langerhans' cells were increased in the epidermis compared to normal skin and contact dermatitis.
D000911:Antibodies, Monoclonal / Q000276:immunology; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology / Q000473:pathology*; D008010:Lichen Planus / Q000276:immunology*; D008264:Macrophages / Q000276:immunology / Q000473:pathology*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology / Q000473:pathology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000473:pathology
D000911:Antibodies, Monoclonal