Contact dermatitis from the epoxy resins tetraglycidyl-4,4'-methylene dianiline and o-diglycidyl phthalate in composite material.
An outbreak of dermatitis occurred in an aircraft factory using epoxy resin composite material. Of 25 operatives, 14 gave positive patch test reactions to the composite material and/or diglycidylether of bisphenol A (DGEBA), tetraglycidyl-4,4'-methylene dianiline (TGMDA), and o-diglycidyl phthalate. This report seems to be the first to demonstrate contact allergy to the two last mentioned epoxy resins. The diglycidylether of bisphenol A used in routine test series picked up only 3 cases of 12 tested.
D000814:Aniline Compounds / Q000009:adverse effects*; D001559:Benzhydryl Compounds; D055598:Chemical Phenomena; D002621:Chemistry; D003188:Composite Resins / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D004852:Epoxy Compounds / Q000009:adverse effects*; D004853:Epoxy Resins / Q000009:adverse effects*; D004988:Ethers, Cyclic / Q000009:adverse effects*; D006801:Humans; D010328:Patch Tests; D010795:Phthalic Acids / Q000009:adverse effects*; D000098826:Bisphenol A Compounds
D000814:Aniline Compounds; D001559:Benzhydryl Compounds; D003188:Composite Resins; D004852:Epoxy Compounds; D004853:Epoxy Resins; D004988:Ethers, Cyclic; D010795:Phthalic Acids; C042840:tetraglycidyl-4,4'-methylene dianiline; C042839:1,2-diglycidyl phthalate; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds