title: The asplenic patient: a consideration for antimicrobial prophylaxis.
abstract: Removal of the spleen predisposes the patient to the development of overwhelming sepsis without a primary site of infection. Transient, usually asymptomatic, bacteremias occur in a wide variety of dental manipulations, particularly those involving the mucous membranes. Occasionally these bacteremias can give rise to serious complications in susceptible patients. A prophylactic preoperative and postoperative antimicrobial regimen is presented for asplenic patients undergoing bacteremia-causing dental treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D003729:Dental Care / Q000009:adverse effects; D003730:Dental Care for Persons with Disabilities; D006801:Humans; D007223:Infant; D010406:Penicillins / Q000627:therapeutic use; D018805:Sepsis / Q000517:prevention & control*; D013154:Spleen / Q000276:immunology / Q000502:physiology; D013156:Splenectomy
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins