title: Repression of UV induction of lambda prophage by caffeine.
abstract: Caffeine was found to function as a repressor of UV-induced lambda prophage when added to the post-irradiation culture medium with both uvrB+ and uvrB- strains of E. coli K12. Caffeine functioned as a repressor of lambda induction at high but not low inducing doses of UV. Caffeine alone at concentrations above 10 mg/plate functioned as an inducer of lambda prophage.
mesh_terms: D010582:Bacteriophage lambda / Q000254:growth & development / Q000528:radiation effects*; D002110:Caffeine / Q000494:pharmacology*; D002478:Cells, Cultured; D004260:DNA Repair; D014466:Ultraviolet Rays; D014775:Virus Activation / Q000187:drug effects / Q000528:radiation effects
chemical_list: D002110:Caffeine