Bronchoscopic phototherapy using hematoporphyrin derivative.
Phototherapy in the presence of hematoporphyrin (HPD) produces cytotoxicity through both energy- and power-dependent mechanisms. The resulting cellular death demonstrates the promise of HPD in the therapy of small cancers. This article reports our clinical experience and follow-up results of treating 19 patients with cancer of the tracheobronchial tree, who have completed at least one course of HPD administered via the flexible fiberoptic bronchoscope.
D001984:Bronchial Neoplasms / Q000188:drug therapy*; D020680:Bronchoscopes; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D005336:Fiber Optic Technology / Q000295:instrumentation; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins / Q000627:therapeutic use*; D006801:Humans; D053685:Laser Therapy; D010778:Photochemotherapy; D014134:Tracheal Neoplasms / Q000188:drug therapy*
D006415:Hematoporphyrins; D017324:Hematoporphyrin Derivative