Allergic contact dermatitis from an organic di-isocyanate.
Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognised. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4'-di-isocyanate has been demonstrated in a factory where it was used to form a surface-coating polyurethane. Attention to hygiene methods may have reduced the incidence of cases.
D000293:Adolescent; D000328:Adult; D001132:Arm; D003485:Cyanates / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D005148:Facial Dermatoses / Q000139:chemically induced*; D005260:Female; D006229:Hand Dermatoses / Q000139:chemically induced*; D006801:Humans; D010328:Patch Tests
D003485:Cyanates; C013606:methylene bis(4-cyclohexylisocyanate)