Weaver-Smith syndrome. A case study with long-term follow-up.
We studied a 6-year-old-boy who was followed up from infancy and who had Weaver-Smith syndrome (WSS), a syndrome characterized by excessive growth, dysmorphic facies, psychomotor retardation, and specific radiologic features. The child's height and bone age were far greater than his chronological age and he demonstrated hypothyroidism at the age of 6 years, but had no endocrinologic abnormalities when he was examined at 11 months of age and again at 4 years of age. We compared the clinical and laboratory features of this child with all other reported cases of WSS.
D000365:Age Determination by Skeleton; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D002658:Developmental Disabilities / Q000150:complications; D005147:Facial Bones / Q000002:abnormalities*; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications; D008297:Male; D008844:Micrognathism / Q000150:complications; D010908:Pituitary Hormones, Anterior / Q000097:blood; D012886:Skull / Q000002:abnormalities*; D013577:Syndrome; D013963:Thyroid Hormones / Q000097:blood
D001786:Blood Glucose; D010908:Pituitary Hormones, Anterior; D013963:Thyroid Hormones