title: Progressive generalized perforating folliculitis.
abstract: A case is presented of a 52-year-old female exhibiting a severe progressive generalized perforating folliculitis accompanied by widespread erythroderma, follicular hyperkeratosis, keratoderma of palms and soles, alopecia of scalp and eyebrows, and nail changes. The disease seemed completely resistant to steroids, adrenocorticotropin, PUVA, cytostatic drugs, and aromatic retinoids. This type of skin reaction does not seem to have been described in the dermatologic literature.
mesh_terms: D003873:Dermatitis, Exfoliative / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005499:Folliculitis / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology; D007642:Keratosis / Q000473:pathology; D008875:Middle Aged; D012867:Skin / Q000473:pathology