[In vitro effect of morphine on oxidative phosphorylation in mitochondria on non-neural cells].
In vitro assays carried on rat liver mitochondria show that morphine is a strong inhibitor of oxidative phosphorylations. Thus the neurotropic drug has also a more general effect on non-nervous cells, effect masked till now by the more impressive effects on the nervous system.
D000818:Animals; D007700:Kinetics; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D009020:Morphine / Q000494:pharmacology*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats
D009020:Morphine
Action de la morphine in vitro sur les oxydations phosphorylantes dans les mitochondries de cellules non nerveuses.