[Value of the analysis of lipoproteins after myocardial infarction].
Lipid and apoprotein constituents of plasma lipoproteins were determined in survivors of myocardial infarction in relation to a control population. Compared to controls, the patients had significantly higher concentrations of total triglycerides, VLDL + LDL - cholesterol and apo-B, but lower concentrations of HLD-cholesterol, HDL2-cholesterol, HDL3-cholesterol, apo A-I and A-II. Survivors with normal lipaemia also had perturbations in HDL and subfractions (HDL2 and HDL3). In addition, the patients exhibited a significant decrease in HDL-cholesterol to VLDL + LDL-cholesterol ratio and in apo A-I to apo-B ratio. These results demonstrate the importance of determining all lipoproteins in future biological studies to evaluate more precisely the relationship between these compounds and atherosclerosis.
D000328:Adult; D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins / Q000097:blood; D001055:Apolipoproteins B; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D003327:Coronary Disease / Q000209:etiology; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D014280:Triglycerides / Q000097:blood
D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D002784:Cholesterol
Intérêt de l'analyse des lipoprotéines après infarctus du myocarde.