[The placenta in trisomy in the last trimester of pregnancy].
18 cases of trisomies 13, 18, or 21 were diagnosed either by examining the caryotype or on clinical criteria. When the placenta was examined in 60% of cases there was a marked retardation of villous maturation with frequent persistence of embryonic forms of villi. The authors suggest that the failure of the villi to mature was often a reflection of pathology in the oocyte which started to show itself at the beginning of the pregnancy.
D002901:Chromosomes, Human, 13-15; D002903:Chromosomes, Human, 19-20; D004314:Down Syndrome / Q000473:pathology; D005260:Female; D006801:Humans; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D014314:Trisomy
Le placenta des trisomies dans le dernier trimestre de la gestation.