[Tolerance to hepatic allografts].
Several experimental data suggest that, compared with other organs, the liver has a privileged status as concerns rejection. In fact, in pigs and rats, spontaneously tolerated liver allografts have been observed with, in rats, constitution of a state of donor-specific transplantation tolerance. Hyperacute rejection, which is a complication of organ allografts in some immunological situations, has not been observed after liver transplantation. In man, acute rejection of liver allografts usually is easily controlled by the immunosuppressive treatment. However, in some cases, an irreversible chronic rejection may occur.
D000818:Animals; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008099:Liver / Q000276:immunology; D016031:Liver Transplantation; D008285:Major Histocompatibility Complex
D007166:Immunosuppressive Agents
Tolérance des allogreffes hépatiques.