[Activation of cell division and nucleic acid synthesis in the corneal epithelium of white rats undergoing repeated exposure to stress].
A study was made of the influence of single and repeated stress on the mitotic activity and synthesis of DNA and RNA in the corneal epithelium of albino rats. The stressors used were fixation on the back during one hour, the influence of 1.5-h hyperthermia (41.5 degrees C), and the influence of hypoxia (4h, 9000 m). Single stress induced the depression of the mitotic activity. The autography tests of DNA synthesis were made constantly. Repeated stress (5 exposures) entailed activation of the synthesis of the nucleic acids and cell division, evidence of a structural trace of stress, in the epithelial tissues.
D000222:Adaptation, Physiological; D000818:Animals; D002455:Cell Division; D003315:Cornea / Q000503:physiopathology*; D004247:DNA / Q000096:biosynthesis*; D004848:Epithelium / Q000503:physiopathology; D008297:Male; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D013312:Stress, Physiological / Q000503:physiopathology*
D012313:RNA; D004247:DNA
Aktivatsiia protsessov kletochnogo deleniia i sinteza nukleinovykh kislot v épitelii rogovitsy belykh krys pri mnogokratnykh stressovykh vozdeĭstviiakh.