Platelet-activating factor causes pulmonary vasoconstriction and edema via platelet-independent leukotriene formation.
D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism*; D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D004487:Edema / Q000503:physiopathology; D008168:Lung / Q000187:drug effects / Q000502:physiology; D008297:Male; D010972:Platelet Activating Factor / Q000494:pharmacology*; D011652:Pulmonary Circulation / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013189:SRS-A / Q000096:biosynthesis*; D014661:Vasoconstriction / Q000187:drug effects*
D010972:Platelet Activating Factor; D013189:SRS-A; D015121:6-Ketoprostaglandin F1 alpha