[Captopril-induced eruptions: occurrence over a 3-year period].
With an informatized sample of 123 patients taking Captopril and treated for a total duration of 1,321 month/patients, the frequency of the dermatological symptoms induced by the drug is related. Pruritus is found in 10,5 p. 100 and rashes in 2,4 p. 100 of cases. The results are compared with those of preceeding reports, although some authors have found a higher percentage because of highin doses of the drug. The clinical features of the rashes and the proposed mechanisms are also reported.
D000328:Adult; D000368:Aged; D002216:Captopril / Q000009:adverse effects*; D055598:Chemical Phenomena; D002621:Chemistry; D004305:Dose-Response Relationship, Drug; D003875:Drug Eruptions / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011392:Proline / Q000031:analogs & derivatives*; D011537:Pruritus / Q000139:chemically induced
D011392:Proline; D002216:Captopril
Toxidermies au Captopril: incidence au cours d'un traitement de 1.321 mois/patients.