[Granuloma formation following intracutaneous administration of procaine-polyvinylpyrrolidone].
After intracutaneous application (dermojet) of procaine polyvinylpyrrolidone (PVP) because of backpain in a 60-year-old woman, multiple brownish-red nodules developed at the injection site within a few days. The histology showed signs of a sarcoid granuloma. There was no clinical evidence for sarcoidosis in this patient. An allergic reaction of the granulomatous type is suspected.
D001416:Back Pain / Q000188:drug therapy; D002110:Caffeine / Q000009:adverse effects* / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D004338:Drug Combinations / Q000009:adverse effects / Q000627:therapeutic use; D003875:Drug Eruptions / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007277:Injections, Jet; D007428:Intradermal Tests; D008854:Microscopy, Electron; D008875:Middle Aged; D011205:Povidone / Q000009:adverse effects* / Q000627:therapeutic use; D011343:Procaine / Q000009:adverse effects* / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
D003692:Delayed-Action Preparations; D004338:Drug Combinations; D002110:Caffeine; D011343:Procaine; C040674:impletol depot Bayer; D011205:Povidone
Granulombildung nach intrakutaner Applikation von Procain-Polyvinylpyrrolidon (PVP).