title: Piperacillin in paediatric surgery.
abstract: 23 infants and children, aged 1 month - 15 years, were treated with piperacillin, a new semi-synthetic penicillin with a broad spectrum of activity. The indications were perforated appendicitis with peritonitis or abscess formation (12 patients), urinary tract infection due to congenital anomalies (3 patients), miscellaneous infections (3 patients) and peroperative prophylactic treatment (5 patients). The clinical response was good. Few adverse reactions were noted. The drug seems to be effective and safe.
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000209:etiology; D000293:Adolescent; D001064:Appendicitis / Q000150:complications; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010406:Penicillins / Q000627:therapeutic use*; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D010878:Piperacillin; D011183:Postoperative Complications / Q000517:prevention & control; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D010406:Penicillins; D010878:Piperacillin