Ischemic optic neuropathy associated with optic disc drusen.
Ischemic optic neuropathy developed in five eyes of four patients with optic nerve drusen. Two of the patients were in their 20s, a decade when idiopathic ischemic optic neuropathy is rare. This argues against a chance concurrence of drusen and idiopathic ischemic optic neuropathy. Infarction of the distal portion of the optic nerve in patients with drusen may result from mechanical distortion of blood vessels in the laminar and prelaminar regions.
D000328:Adult; D005109:Extracellular Matrix / Q000648:ultrastructure*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007238:Infarction / Q000473:pathology; D007511:Ischemia / Q000473:pathology*; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D009900:Optic Nerve / Q000098:blood supply*; D009901:Optic Nerve Diseases / Q000473:pathology*; D009902:Optic Neuritis / Q000473:pathology; D010211:Papilledema / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D014792:Visual Acuity; D014794:Visual Fields