title: Stimulation of fracture healing with electromagnetic fields of extremely low frequency (EMF of ELF).
abstract: This randomized, controlled study was performed to evaluate how electromagnetic fields affect the accumulation of 99mTechnetium - methylendiphosphonate (Tc-MDP) in fresh fractures. Thirty women with Colles' fractures, aged 50-70 years, participated in this study--some in a control group and some in a treated group. After reduction, all patients were immobilized for four weeks. After randomization, 15 patients were treated by electromagnetic fields of extremely low frequency (EMF of ELF ), which were generated by a coil and a battery-powered portable current generator during the time of immobilization. The frequency of the alternating magnetic field was 1-1000 Hz; the magnitude was 4 gauss [RMS (root-mean-square) value]. The scintigrams were performed one, two, four, and eight weeks after the injury. The activity ratio in the fracture area was significantly higher at the examination of one and two weeks (p less than 0.05, p less than 0.01) in the treated group than it was in the control group. The clinical relevance of the results is not known, but one interpretation of the data is that the stimulation with EMF of ELF improves (accelerates) the early phase of fracture healing. The data warrant further investigation of fresh fracture treatment with this method.
mesh_terms: D000368:Aged; D003100:Colles' Fracture / Q000503:physiopathology / Q000628:therapy*; D004164:Diphosphonates / Q000378:metabolism; D004599:Electric Stimulation Therapy / Q000379:methods*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D055909:Magnetic Field Therapy; D008875:Middle Aged; D011885:Radius Fractures / Q000628:therapy*; D011897:Random Allocation; D013667:Technetium / Q000378:metabolism; D013669:Technetium Tc 99m Medronate; D014945:Wound Healing
chemical_list: D004164:Diphosphonates; D013667:Technetium; D013669:Technetium Tc 99m Medronate