[HLA and Huntington chorea].
Twenty-three patients with documented Huntington's Chorea were typed for 54 HLA antigens belonging to A, B and C loci. The control group was constituted by 124 healthy subjects of the same ethnic background. Patients and controls were typed with the same antisera. In this study no significant differences in the distribution of HLA antigens between the two groups were found. These data indicate that Huntington's Chorea is not associated with any of HLA antigens serologically determined. However, these findings do not exclude the possibility that other genes, whether or not related to MHC, could be responsible of the family inheritance of the disease.
D000328:Adult; D000368:Aged; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D006816:Huntington Disease / Q000235:genetics*; D008297:Male; D008875:Middle Aged
D005819:Genetic Markers; D006680:HLA Antigens
HLA et chorée de Huntington.