title: Isotopic identification of intestinal strangulation.
abstract: A small series of eleven dogs prepared with a strangulating segment of jejunum demonstrated that a radionuclide, 99mTc-labelled albumin, concentrates in the lumen and bowel wall of the affected intestinal segment. Modern scanning equipment accurately localized the strangulating loop. This technique has the potential of identifying patients with intestinal obstruction, in whom strangulation is a factor, prior to the development of impaired arterial inflow and frank gangrene. These findings confirmed earlier obstructions that were reported when nuclear scanning instrumentation was less sophisticated. Identification of patients at risk for intestinal strangulation requires a high index of suspicion. Excruciating cramping abdominal pain out of proportion to physical findings, roentgenogram evidence, and laboratory studies should alert the physician to the possibility of intestinal ischemia and closed loop obstruction. Radionuclide scanning in such cases may be of assistance in defining or excluding the diagnosis of a strangulating mechanism. The test is simple, relatively economical, and represents a low risk procedure to patients. It would have no place when the classic physical and laboratory findings of intestinal infarction are present.
mesh_terms: D000818:Animals; D004285:Dogs; D004912:Erythrocytes; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging*; D007422:Intestines / Q000098:blood supply; D007553:Isotope Labeling; D007583:Jejunum / Q000098:blood supply; D008722:Methods; D008833:Microcirculation; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate
chemical_list: D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate