Mezlocillin treatment of septicemia in general hospitals.
Gramnegative septicemia in 23 patients from different Norwegian departments of general medicine or surgery was treated with mezlocillin. Most of the patients were old, and 14 patients were considered compromised due to underlying disease. In the majority of cases the septicemia originated from urinary tract infections. Uneventful recovery was accomplished in 16 patients (70%) and another 5 cases improved. In 2 patients no clinical effects were observed within 3 days of treatment. Apart from diarrhoea in 5 of the cases, no side-effects occurred. Mezlocillin proved to be a safe and efficient drug for the treatment of gramnegative septicemias of the type that is most commonly encountered in Norwegian general hospitals.
D000328:Adult; D000368:Aged; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D006088:Gram-Negative Aerobic Bacteria / Q000187:drug effects; D006801:Humans; D007709:Klebsiella / Q000187:drug effects; D008297:Male; D008802:Mezlocillin; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000009:adverse effects / Q000627:therapeutic use*; D011513:Proteus mirabilis / Q000187:drug effects; D018805:Sepsis / Q000188:drug therapy* / Q000382:microbiology
D010406:Penicillins; D008802:Mezlocillin