title: Luteinized unruptured follicle syndrome: hormone assay on peritoneal fluid in a laparoscopic study of infertile women.
abstract: 33 infertile women with normal ovulatory cycles were investigated for the presence of a Luteinized Unruptured Follicle Syndrome (L.U.F.) using steroid hormone assays in peritoneal fluid and laparoscopic visualization of ovulation stigmata. We failed to identify a stigma in 36% (12) of the patients in the early luteal phase, 1 subject had a cystic corpus luteum and in 4 cases no diagnosis was made due to the presence of adhesions. The mean hormone concentrations in PF were significantly higher when the stigma was present (17-beta-estradiol, P less than 0,05; progesterone, P less than 0,01; 17-oh-progesterone, P less than 0,05). The two groups (with and without ovulation stigmata) showed no differences in plasma levels of Estradiol (E2) and Progesterone (P). Stigmata were detected only in 17% of subjects with concomitant endometriosis. 3 patients with a luteal phase defect showed low levels of steroids in PF in spite of the presence of an ovulation stigma.
mesh_terms: D019326:17-alpha-Hydroxyprogesterone; D000858:Anovulation / Q000378:metabolism* / Q000473:pathology; D001202:Ascitic Fluid / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006801:Humans; D006908:Hydroxyprogesterones / Q000378:metabolism; D007247:Infertility, Female / Q000378:metabolism* / Q000473:pathology; D010535:Laparoscopy; D010061:Ovulation Detection; D011374:Progesterone / Q000378:metabolism; D013577:Syndrome
chemical_list: D012739:Gonadal Steroid Hormones; D006908:Hydroxyprogesterones; D011374:Progesterone; D004958:Estradiol; D019326:17-alpha-Hydroxyprogesterone