Cerebrospinal fluid granulocytes in bacterial meningitis have E receptors.
Cerebrospinal fluid (CSF) granulocytes from 4 patients with bacterial meningitis were tested for rosette formation with sheep erythrocytes (E), a standard assay for T lymphocytes. CSF granulocytes from all patients formed E rosettes, although to a varying degree (66, 63, 17 and 2%, respectively). E rosettes could not be demonstrated with granulocytes from peripheral blood from the patient with 66% E-rosette-forming granulocytes in the CSF.
D000208:Acute Disease; D000293:Adolescent; D000368:Aged; D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006098:Granulocytes / Q000378:metabolism*; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000134:cerebrospinal fluid* / Q000276:immunology; D008586:Meningitis, Pneumococcal / Q000134:cerebrospinal fluid* / Q000276:immunology; D008875:Middle Aged; D011817:Rabbits; D011951:Receptors, Complement / Q000032:analysis; D017463:Receptors, Complement 3b; D011961:Receptors, Fc / Q000032:analysis*; D017452:Receptors, IgG; D012397:Rosette Formation; D012756:Sheep
D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011961:Receptors, Fc; D017452:Receptors, IgG