Studies on the biosynthesis of bialaphos (SF-1293). 4. Production of phosphonic acid derivatives, 2-hydroxyethylphosphonic acid, hydroxymethylphosphonic acid and phosphonoformic acid by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D017245:Foscarnet; D006540:Herbicides / Q000138:chemical synthesis*; D009154:Mutation; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000378:metabolism; D009943:Organophosphorus Compounds / Q000138:chemical synthesis*; D010746:Phosphonoacetic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D013302:Streptomyces / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D006540:Herbicides; D063065:Organophosphonates; D009943:Organophosphorus Compounds; C542570:hydroxymethylphosphonate; C003122:bialaphos; D017245:Foscarnet; D010746:Phosphonoacetic Acid