Murine renal cell carcinoma: a suitable human model.
Many models of renal cell carcinoma are available. They have been observed in various species of animals. However, a renal adenocarcinoma which metastasizes, is available for study, and can be serially transplanted in BALB/c mice, appears to be the currently favored model. Our results reported herein describe a study on tumor kinetics, the effects of chemotherapy and other manipulations which appear relevant to the human state. A brief description of other available models is provided.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D000818:Animals; D004054:Diethylstilbestrol / Q000494:pharmacology; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D007700:Kinetics; D008297:Male; D008525:Medroxyprogesterone / Q000031:analogs & derivatives / Q000494:pharmacology; D017258:Medroxyprogesterone Acetate; D051379:Mice; D008807:Mice, Inbred BALB C; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D013739:Testosterone / Q000494:pharmacology
D013739:Testosterone; D004054:Diethylstilbestrol; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone