[Immunologic phenomena in habitual abortion].
12 women with recurrent abortions are investigated for various immunological parameters. Couples studied shared several HLA antigens, those women do not develop HLA' antibodies and cellular cytotoxicity against their husband. Their serum has an abnormal glycoprotein, migrating in the alpha globulin zone, precipitating with anti beta globulin serum. The women studied with recurrent abortions never possessed the Blocking Factor present in the serum of pregnant women, able to inhibit a cellular cytotoxicity reaction in vitro. It is proposed a reliable and simple test which could inform on the outcome of abortions.
D000026:Abortion, Habitual / Q000276:immunology*; D002850:Chromatography, Gel; D003601:Cytotoxicity Tests, Immunologic; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D011247:Pregnancy
D006680:HLA Antigens; D007074:Immunoglobulin G
Phénomènes immunologiques au cours des avortements répétés.