[The role of the population gene pool in meningococcal infection morbidity].
The character of the distribution of HLA antigens in patients with meningococcal infection among Russians and Touvinians was revealed. The markers of susceptibility to meningococcal infection were detected in each national group. These markers were HLA-Bw22 in Touvinians. The gene of susceptibility to meningococcal infection occurred among Touvinians 2.3 times more frequently. This was probably the cause of a higher morbidity rate in meningococcal infection among Touvinians than among Russians.
D002648:Child; D004198:Disease Susceptibility; D005006:Ethnicity; D005788:Gene Pool; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008589:Meningococcal Infections / Q000453:epidemiology / Q000235:genetics*; D012426:Russia / Q000208:ethnology
D006680:HLA Antigens
Rol'populiatsionnogo genofonda v formirovanii urovnia zabolevaemosti meningokokkovoĭ infektsieĭ.