title: B-L antigens (Ia-like antigens) of the chicken major histocompatibility complex.
abstract: This paper reviews the present knowledge of B-L antigens encoded by the chicken B complex as regards to the following aspects: (1) identification and cellular expression, (2) structural studies, (3) evidence for two distinct populations of B-L antigens, (4) mapping of B-L loci of the B complex, (5) B-L and immune response, and (6) the role of the B-L antigens for the control of mixed lymphocyte reactions (MLR) and graft-versus-host (GVH) reactions. It is concluded that B-L antigens of the chicken exhibit extensive homology with mammalian Ia antigens. A genetic map of the B complex is presented.
mesh_terms: D000818:Animals; D002645:Chickens / Q000276:immunology*; D002874:Chromosome Mapping; D005455:Fluorescent Antibody Technique; D005802:Genes, MHC Class II; D000949:Histocompatibility Antigens Class II / Q000235:genetics / Q000276:immunology*; D007959:Lymphocyte Culture Test, Mixed; D008285:Major Histocompatibility Complex
chemical_list: D000949:Histocompatibility Antigens Class II