[Implication of hypothalamic structures in indolaminergic mechanisms of paradoxical sleep].
Intratissue injection of 1 to 20 micrograms of L-5 HTP in numerous areas of the cat brainstem failed to reverse P-chlorophenylalanine induced insomnia. On the other hand, injection of 2 to 7 micrograms of L-5 HTP in the ventrolateral hypothalamus induced both slow wave sleep and paradoxical sleep after 36 and 76 min.
D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D001933:Brain Stem / Q000187:drug effects; D002415:Cats; D005260:Female; D010134:Fenclonine / Q000494:pharmacology; D007031:Hypothalamus / Q000187:drug effects / Q000502:physiology*; D007211:Indoles / Q000502:physiology*; D008297:Male; D012895:Sleep, REM / Q000502:physiology*
D007211:Indoles; D006916:5-Hydroxytryptophan; D010134:Fenclonine
Mise en jeu de structures hypothalamiques dans les mécanismes indolaminergiques du sommeil paradoxal.