The acquired immunodeficiency syndrome in patients with hemophilia.
Since mid-1981 the Centers for Disease Control (CDC) has received reports of more than 1900 cases of the acquired immunodeficiency syndrome. These cases had either Kaposi's sarcoma confirmed by biopsy or a life-threatening opportunistic infection confirmed by biopsy or culture. In January 1982 a hemophiliac with Pneumocystis carinii pneumonia was reported to the CDC, and by July 1982 two other hemophiliacs had developed P. carinii pneumonia. During the next 12 months a total of 22 confirmed cases of the acquired immunodeficiency syndrome occurred in hemophiliacs, 17 in the United States and 5 outside the United States. We report the nature of the epidemic of the acquired immunodeficiency syndrome in hemophiliacs and summarize pertinent clinical aspects.
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000635:transmission; D000293:Adolescent; D000328:Adult; D000368:Aged; D001769:Blood; D002648:Child; D006467:Hemophilia A / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D006377:T-Lymphocytes, Helper-Inducer; D050378:T-Lymphocytes, Regulatory; D065227:Transfusion Reaction; D014481:United States