Removal of sulfated (heparan sulfate) or nonsulfated (hyaluronic acid) glycosaminoglycans results in increased permeability of the glomerular basement membrane to 125I-bovine serum albumin.
D000818:Animals; D001345:Autoradiography; D001485:Basement Membrane / Q000098:blood supply / Q000378:metabolism; D002199:Capillary Permeability; D002810:Chondroitinases and Chondroitin Lyases / Q000494:pharmacology; D006025:Glycosaminoglycans / Q000378:metabolism*; D019763:Heparin Lyase; D006497:Heparan Sulfate / Q000378:metabolism*; D006820:Hyaluronic Acid / Q000378:metabolism*; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology; D007678:Kidney Glomerulus / Q000378:metabolism*; D008297:Male; D008854:Microscopy, Electron; D010477:Perfusion; D011133:Polysaccharide-Lyases / Q000494:pharmacology; D051381:Rats; D012710:Serum Albumin, Bovine / Q000494:pharmacology*
D002810:Chondroitinases and Chondroitin Lyases; D006025:Glycosaminoglycans; D019763:Heparin Lyase; D006497:Heparan Sulfate; D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase; D011133:Polysaccharide-Lyases; D012710:Serum Albumin, Bovine