[Study of critical levels of 3 antistreptococcal antibodies by data analysis].
Prinqual, a new statistical data-analysis method was used to determine the critical titers of antistreptolysin O (ASLO), anti-DNase B (ADB) and antistreptokinase (ASK) in the sera of 104 patients with suspected streptococcal infection and 121 blood-donors. The whole range from pathological to normal was thus covered, thereby avoiding bias concerning the proportion of normal titers in a control population. Another advantage of the method was that the titers of the 3 antibodies were considered simultaneously and the semi-quantitative results of serological tests were avoided. It appeared from this study that the upper limits of normal values were: ASLO, 100 U; ADB, 240 U and ASK, 40 U. The first probably pathological values were: ASLO, 150 U; ADB, 480 U and ASK, 320 U. These results are compared with those available in the literature.
D000907:Antibodies, Bacterial / Q000032:analysis*; D000989:Antistreptolysin / Q000032:analysis; D001426:Bacterial Proteins; D001782:Blood Donors; D003851:Deoxyribonucleases / Q000276:immunology; D006801:Humans; D012016:Reference Values; D012698:Serologic Tests; D013223:Statistics as Topic; D013290:Streptococcal Infections / Q000175:diagnosis*; D013291:Streptococcus / Q000276:immunology*; D013301:Streptolysins / Q000276:immunology
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D013301:Streptolysins; C014338:antistreptokinase; C025964:streptolysin O; D000989:Antistreptolysin; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B
Etude des taux critiques de trois anticorps antistreptococciques par l'analyse des données.