title: Pigmentary incontinence in fixed drug eruptions. Histologic and electron microscopic findings.
abstract: Pigmentary incontinence is a phenomenon observed in some inflammatory skin disorders. Clinically it may be seen as a slate-colored pigmentation. Histologically it is seen as an accumulation of melanin in the upper dermis. The possible mechanism for development of pigmentary incontinence is discussed based on a review of the literature and electron microscopic studies of fixed drug eruption.
mesh_terms: D003875:Drug Eruptions / Q000473:pathology*; D004817:Epidermis / Q000648:ultrastructure; D006801:Humans; D008264:Macrophages / Q000648:ultrastructure; D008543:Melanins / Q000032:analysis; D008544:Melanocytes / Q000648:ultrastructure; D010859:Pigmentation Disorders / Q000473:pathology; D012880:Skin Pigmentation
chemical_list: D008543:Melanins