title: [Treatment of chronic post-traumatic infections of the locomotor apparatus with methyl-polymethacrylate pearls containing gentamicin].
abstract: A new efficient method is presented based on the surgical cure of the infectious focus and the introductions of strings of methyl-polimetacrylate beads containing gentamycin. The method was demonstrated to be far superior when compared with both general antibiotherapy, and local antibiotherapy with antibiotic powder or with instillations of antibiotic solutions. The failures of this new treatment represented only 24.5% of all cases. The presence of gentamycin-containing beads in the infection focus provides constant and prolonged delivery of the antibiotic in highly bactericidal concentration.
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000188:drug therapy*; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D020366:Methylmethacrylate; D008768:Methylmethacrylates / Q000627:therapeutic use*; D008875:Middle Aged; D010000:Osteitis / Q000188:drug therapy*; D010003:Osteoarthritis / Q000188:drug therapy*; D010019:Osteomyelitis / Q000188:drug therapy*; D014947:Wounds and Injuries / Q000150:complications
chemical_list: D005839:Gentamicins; D008768:Methylmethacrylates; D020366:Methylmethacrylate
vernacular_title: Tratamentul infecţiilor cronice posttraumatice ale aparatului locomotor cu perle de polimetacrilat de metil gentaminizat.