title: Primary reticulum cell sarcoma of the brain presenting as steroid-responsive optic neuropathy.
abstract: A 23-year-old woman presented with subacute monocular visual loss clinically resembling optic neuritis. CT scan revealed a cerebellar mass, biopsy of which led to the diagnosis of reticulum cell sarcoma (RCS). Corticosteroid therapy resulted in improvement of vision and a decrease in disc edema; this resolution was documented radiographically. While optic nerve involvement is sometimes seen in association with systemic lymphoproliferative disease, optic neuropathy as a manifestation of primary cerebral RCS is rare.
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis*; D002528:Cerebellar Neoplasms / Q000175:diagnosis; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis*; D009902:Optic Neuritis / Q000175:diagnosis* / Q000188:drug therapy; D010211:Papilledema / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
chemical_list: D003907:Dexamethasone