title: Immunization with irradiated larvae against Dictyocaulus filaria in young lambs.
abstract: In the lungworm-endemic areas of Kashmir, 6-10 week old lambs of Karnah and Kashmir Merino breeds were vaccinated with two doses of 50 kR gamma-irradiated larvae of Dictyocaulus filaria, given a month apart. Assessed on the basis of reduced prevalence and significantly lower faecal larval output over an eight-month observation period, vaccinated lambs showed a high degree of resistance to naturally acquired D. filaria infection. The results also show that vaccination against D. filaria provided some degree of protection against infection with other lungworm species.
mesh_terms: D000818:Animals; D004021:Dictyocaulus / Q000276:immunology* / Q000528:radiation effects; D004022:Dictyocaulus Infections / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control*; D005243:Feces / Q000469:parasitology; D005720:Gamma Rays; D007814:Larva / Q000276:immunology / Q000528:radiation effects; D008681:Metastrongyloidea / Q000276:immunology*; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary*