Enhancement of the radiation effect by fibrinolysin and quantitative pattern of the change of tumor radiosensitivity.
Radiomodifying action of fibrinolysin was studied during radiation treatment in experimental transplanted tumors. It has been established that the application of fibrinolysin prior to radiation increases the inhibition of the growth rate of Pliss lymphosarcoma and Sarcoma 45, as evidenced by the decrease of the tumor volume, the increase of the dose change factor and the animals survival.
D000818:Animals; D003131:Combined Modality Therapy; D005341:Fibrinolysin / Q000627:therapeutic use*; D008297:Male; D009374:Neoplasms, Experimental / Q000097:blood / Q000473:pathology / Q000532:radiotherapy*; D011836:Radiation Tolerance; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains
D011838:Radiation-Sensitizing Agents; D005341:Fibrinolysin