title: [Characteristics of the causative agents of the influenza A (H3N2) epidemic in Leningrad in 1983].
abstract: Investigation of influenza A (H3N2) epidemic of 1983 in Leningrad revealed simultaneous circulation of 3 antigenic variants similar to A/Bangkok/1/79, A/Bangkok/2/79, and A/Philippines/2/82 with significant predominance of the first antigenic variant. The viruses related to A/Philippines/2/82 comprising one-third of all isolations produced antibodies of a wide spectrum unlike the other two variants whose antisera neutralize actively the homologous virus only. The possibility of selecting epidemic strains of the A/Philippines/2/82 variety as vaccine strain candidates is discussed.
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D014644:Genetic Variation; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007114:Immunization; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000382:microbiology*; D008168:Lung / Q000382:microbiology; D051379:Mice; D009439:Neuraminidase / Q000037:antagonists & inhibitors; D051381:Rats; D012426:Russia; D014505:Urban Population; D014779:Virus Replication
chemical_list: D000956:Antigens, Viral; D009439:Neuraminidase
vernacular_title: Osobennosti vozbuditeleĭ épidemii grippa A (H3N2) v Leningrade v 1982 g.