[Y-chromosome polysomy and expression of the H-Y antigen].
The sex-differentiation H-Y antigen was studied in 5 males subjects with Y-chromosome polysomy. All had gonadal deficiency and significant decrease of H-Y antigen as compared with 77 normal 46, XY male controls. Men with additional Y-gonosomes may be hypogonadic or, more often, fertile, as was probably the case with the 3 patients with very high H-Y antigen titers previously described by other research workers. The phenotypic polymorphism of these subjects therefore seems to be parallel with their H-Y antigen polymorphism and there may be, in our 5 subjects, a relationship between abnormal spermatogenesis and H-Y antigen deficiency.
D000328:Adult; D005260:Female; D005786:Gene Expression Regulation; D006182:H-Y Antigen / Q000032:analysis / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012729:Sex Chromosome Aberrations / Q000276:immunology*; D014997:XYY Karyotype / Q000276:immunology; D014998:Y Chromosome / Q000276:immunology
D006182:H-Y Antigen
Polysomie du chromosome Y et expression de l'antigène H-Y.