Serum anticonvulsant concentrations and the risk of drug induced skin eruptions.
In two prospective studies of anticonvulsant therapy there was a high incidence of drug-induced skin reactions to phenytoin (7%) and carbamazepine (16.6%). High initial serum concentrations of these drugs appeared to be a factor influencing the occurrence of such skin reactions.
D002220:Carbamazepine / Q000009:adverse effects* / Q000097:blood; D003399:Craniotomy; D003875:Drug Eruptions / Q000097:blood*; D004827:Epilepsy / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects* / Q000097:blood; D011183:Postoperative Complications / Q000097:blood / Q000188:drug therapy
D002220:Carbamazepine; D010672:Phenytoin