[Comparison of effect and tolerance of mezlocillin with carbenicillin in the treatment of bacterial infections].
Of 60 patients who were suffering from bacterial infections, 30 were treated with mezlocillin and 30 with carbenicillin in a randomized study. The patients received the recommended daily doses of 16 g and 30 g, respectively. Clinical efficacy was found in all patients. Mezlocillin eliminated the strains more reliably than carbenicillin. The bacteriological success rate was 27/30 and 16/30, respectively. We should also take into account the fact that the six patients with cholecystitis who were treated with carbenicillin could not be controlled after treatment.
D001424:Bacterial Infections / Q000188:drug therapy*; D002228:Carbenicillin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008802:Mezlocillin; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use*; D011897:Random Allocation
D010406:Penicillins; D002228:Carbenicillin; D008802:Mezlocillin
Vergleich der Wirkung und Verträglichkeit von Mezlocillin mit Carbenicillin bei der Behandlung bakterieller Infektionen.