title: [Stereotyped chromosome abnormalities in human leukemia and lymphoma].
abstract: That chromosomal abnormalities in leukaemias and lymphomas are not non-randomly distributed has been demonstrated by banding techniques. Abnormalities characteristic of a given type of proliferation are described. The chromosomal breakpoints corresponding to these changes are located close to the sequences encoding for cellular oncogens (c-onc), which justifies the growing interest in the cytogenetic study of malignant cells.
mesh_terms: D002051:Burkitt Lymphoma / Q000235:genetics; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002902:Chromosomes, Human, 16-18; D002903:Chromosomes, Human, 19-20; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D007951:Leukemia, Myeloid / Q000235:genetics; D015470:Leukemia, Myeloid, Acute / Q000235:genetics; D008223:Lymphoma / Q000235:genetics*; D009857:Oncogenes; D014178:Translocation, Genetic; D014314:Trisomy
vernacular_title: Anomalies chromosomiques stéréotypées des leucémies et lymphomes humains.