Some proteins not belonging to the clotting or to the kallikrein-kinin system altered by kallikrein.
Plasma kallikrein activation occurs frequently during blood drawing and subsequent plasma handling. The purified enzyme was incubated with ceruloplasmin, inter-alpha-trypsin inhibitor and complement factor C4. Proteolysis caused by this enzyme was compared with the degradative effects of plasmin and thrombin. Among these proteins C4 proved to be most easily degraded; its cleavage products can interact with C4-binding protein.
D001777:Blood Coagulation; D001798:Blood Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000097:blood; D002570:Ceruloplasmin / Q000378:metabolism; D003181:Complement C4 / Q000032:analysis; D003169:Complement Inactivator Proteins; D005341:Fibrinolysin / Q000378:metabolism; D016167:Integrin alphaXbeta2; D007610:Kallikreins / Q000097:blood*; D007705:Kinins / Q000378:metabolism; D013917:Thrombin / Q000378:metabolism
D001798:Blood Proteins; D002352:Carrier Proteins; D003181:Complement C4; D003169:Complement Inactivator Proteins; D016167:Integrin alphaXbeta2; D007705:Kinins; D002570:Ceruloplasmin; D007610:Kallikreins; D013917:Thrombin; D005341:Fibrinolysin