title: [Meleda disease - akroerythrokeratoderma].
abstract: The authors reexamined eight patients with autochthonous Meleda disease. They further report about three other patients with this disease living on the island of Mljet (Meleda). Fron the clinical appearance the authors conclude that Meleda disease belongs to the group of Akroerythrokeratodermias. In no case an enhancement of the keratinisation disorder had occurred. The hyperkeratosis but not the erythrodermatic signs drastically reduced within two weeks after a treatment with an aromatic retinoid (Ro 10-9359).
mesh_terms: D000328:Adult; D000368:Aged; D005050:Etretinate / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology
chemical_list: D005050:Etretinate
vernacular_title: Die Meleda-Krankheit - eine Akroerythrokeratodermie.