title: Effects of nutritional supplementation on IQ and certain other variables associated with Down syndrome.
abstract: In a double-blind study, 24 Down syndrome children, ages 6 to 17 years living at home, were given a megadose multi-vitamin/mineral supplement for 4 months. A matched group of 23 children received a placebo in identical form. The children's IQ, vision, and visual-motor integration were tested before and after supplementation, and weekly checks were made to monitor behavioral changes. No differences were found on any measures as a result of supplementation.
mesh_terms: D000293:Adolescent; D002648:Child; D004311:Double-Blind Method; D004314:Down Syndrome / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D007360:Intelligence / Q000187:drug effects*; D008297:Male; D008903:Minerals / Q000627:therapeutic use*; D011597:Psychomotor Performance / Q000187:drug effects; D012917:Social Adjustment; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D008903:Minerals; D014815:Vitamins