The levels of superoxide dismutase, catalase, and carbonic anhydrase in erythrocytes of patients with Down's syndrome.
The levels of cytoplasmic superoxide dismutase ( SOD1 ), catalase (CAT'ase), and carbonic anhydrase isoenzymes (CA-B and CA-C) were determined in the erythrocytes from 11 male patients with Down's syndrome. The levels of SOD1 and CAT'ase, as well as CA-B showed significant increases compared with those in normal controls, whereas the CA-C level did not change substantially. In addition, a positive correlation was noted between the levels of SOD1 and of CAT'ase (r = 0.764).
D000293:Adolescent; D000328:Adult; D002256:Carbonic Anhydrases / Q000097:blood*; D002374:Catalase / Q000097:blood*; D002648:Child; D004314:Down Syndrome / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008297:Male; D013482:Superoxide Dismutase / Q000097:blood*
D007527:Isoenzymes; D002374:Catalase; D013482:Superoxide Dismutase; D002256:Carbonic Anhydrases