[Early pulmonary lesions from hyperoxia in rats].
Normal rats exposed during one hour to pure normobaric oxygen, present pulmonary parenchymatous lesions: diffuse congestion, subpleural atelectasis in dissiminated small areas and hemorragic infarcts. Neither alveolar oedema nor abnormal vascular permeability have been observed. The lesions are not suppressed by pretreatment with promethazine (1 or 2 mg. 100 g-1).
D000818:Animals; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control; D008171:Lung Diseases / Q000209:etiology* / Q000517:prevention & control; D010100:Oxygen / Q000633:toxicity*; D011398:Promethazine / Q000627:therapeutic use; D001261:Pulmonary Atelectasis / Q000209:etiology / Q000517:prevention & control; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D011398:Promethazine; D010100:Oxygen
Sur les lésions pulmonaires précoces de l'hyperoxie chez le rat.