title: Basement membrane heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma.
abstract: Heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma has been purified and partially characterized. The proteoglycan has an apparent Mr of 750 000, 35% of which represents the core protein. The core protein seems to be homogeneous, whereas the heparan sulfate chains are heterogeneous with an Mr of about 50 000-70 000, with 30% of the glucosamine being N-sulfated. Antibodies raised against the core protein of the heparan sulfate proteoglycan reacted with basement membranes of various rat and human tissue.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001485:Basement Membrane / Q000032:analysis*; D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis* / Q000276:immunology; D004407:Dysgerminoma / Q000032:analysis* / Q000473:pathology; D006025:Glycosaminoglycans / Q000032:analysis*; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate / Q000032:analysis* / Q000276:immunology; D006595:Hexosamines / Q000032:analysis; D011509:Proteoglycans / Q000032:analysis*; D051381:Rats
chemical_list: D000596:Amino Acids; D011508:Chondroitin Sulfate Proteoglycans; D006025:Glycosaminoglycans; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate; D006595:Hexosamines; D011509:Proteoglycans