Morphological aspects of the rat kidney preserved by cold storage. I. Glomerular morphometric changes.
The absolute density of glomeruli in the microscopic field was determined in the rat kidney preserved by cold storage for 24, 48, 72 and 96 hrs in two different media: Sacks (hyperosmolar electrolytic solution of intracellular type) and Plasmagel (gelatin solution 4%). Progressive, statistically significant (p less than 0.01) decrease of glomerular density at 24 and 48 hrs was followed by return to initial values at 96 hrs. Decrease of the glomerular density was greater with Plasmagel.
D000818:Animals; D003720:Densitometry; D007668:Kidney; D007678:Kidney Glomerulus / Q000033:anatomy & histology*; D009926:Organ Preservation / Q000379:methods*; D051381:Rats; D012034:Refrigeration; D014021:Tissue Preservation / Q000379:methods*