title: Contact dermatitis from the epoxy resins tetraglycidyl-4,4'-methylene dianiline and o-diglycidyl phthalate in composite material.
abstract: An outbreak of dermatitis occurred in an aircraft factory using epoxy resin composite material. Of 25 operatives, 14 gave positive patch test reactions to the composite material and/or diglycidylether of bisphenol A (DGEBA), tetraglycidyl-4,4'-methylene dianiline (TGMDA), and o-diglycidyl phthalate. This report seems to be the first to demonstrate contact allergy to the two last mentioned epoxy resins. The diglycidylether of bisphenol A used in routine test series picked up only 3 cases of 12 tested.
mesh_terms: D000814:Aniline Compounds / Q000009:adverse effects*; D001559:Benzhydryl Compounds; D055598:Chemical Phenomena; D002621:Chemistry; D003188:Composite Resins / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D004852:Epoxy Compounds / Q000009:adverse effects*; D004853:Epoxy Resins / Q000009:adverse effects*; D004988:Ethers, Cyclic / Q000009:adverse effects*; D006801:Humans; D010328:Patch Tests; D010795:Phthalic Acids / Q000009:adverse effects*; D000098826:Bisphenol A Compounds
chemical_list: D000814:Aniline Compounds; D001559:Benzhydryl Compounds; D003188:Composite Resins; D004852:Epoxy Compounds; D004853:Epoxy Resins; D004988:Ethers, Cyclic; D010795:Phthalic Acids; C042840:tetraglycidyl-4,4'-methylene dianiline; C042839:1,2-diglycidyl phthalate; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds