title: Influence of prepubertal consumption of zearalenone on sexual development of boars.
abstract: Littermate pairs of crossbred boars were fed 40 ppm zearalenone from 14 to 18 weeks of age, and the effects on reproductive development were examined. Compared to controls, boars fed zearalenone subsequently had reduced libido scores (P greater than.05), and fewer treated animals exhibited mating behavior. Plasma concentrations of testosterone were depressed (P greater than .05) during consumption of zearalenone. Zearalenone did not significantly affect age at which sperm were first voided in the urine (P greater than .25). Body weight and testicular size were not affected by zearalenone. At 36 weeks of age, testicular weight, epididymal weight, spermatid numbers, motility of cauda epididymal sperm and testicular morphology did not differ between control boars and those that had consumed zearalenone.
mesh_terms: D000735:Androstenedione / Q000097:blood; D000818:Animals; D003864:Depression, Chemical; D004032:Diet; D004958:Estradiol / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D012118:Resorcinols / Q000494:pharmacology*; D012726:Sexual Behavior, Animal / Q000187:drug effects; D012741:Sexual Maturation / Q000187:drug effects*; D013552:Swine / Q000502:physiology*; D013739:Testosterone / Q000097:blood; D015025:Zearalenone / Q000494:pharmacology*
chemical_list: D012118:Resorcinols; D013739:Testosterone; D000735:Androstenedione; D004958:Estradiol; D015025:Zearalenone; D007986:Luteinizing Hormone