Experimental splenosis: a comparative study in rats.
The growth of the splenic remnant after partial splenectomy and autogenous splenic implants was compared in immature rats. Implants placed in the subcutaneous pouch of the anterior abdominal wall and the retroperitoneal space had none or minimal regeneration. Splenulus formed in the omental wrap were small, multiple and the combined weight was less than the original graft tissue, and more ectopic splenulus and intra-abdominal adhesions were formed. Splenic remnants after three-quarter splenectomy with an intact blood supply grew to 30-46% of the weight of the spleen of the control; and increased in size as the animal matured.
D000009:Abdominal Muscles; D000818:Animals; D008297:Male; D009929:Organ Size; D051381:Rats; D012038:Regeneration; D012187:Retroperitoneal Space; D013154:Spleen / Q000166:cytology / Q000502:physiology / Q000637:transplantation*; D013156:Splenectomy; D014182:Transplantation, Autologous