title: High tolerance of broilers to vomitoxin from corn infected with Fusarium graminearum.
abstract: Corn purposely infected with Fusarium graminearum was found to contain 800 to 900 mg vomitoxin/kg. Contaminated corn was substituted for control corn at 0, 6, 12, 18, and 24% in a corn-soybean meal ration. Broiler cockerels were given each experimental diet from 6 to 11 days of age; then sample groups were necropsied. Remaining birds were subsequently offered commercial starter for 2 days and sample groups again necropsied. Growth and diet consumption were not significantly reduced until contaminated corn exceeded 12% of the ration (116 mg vomitoxin/kg). Alertness, coordination, and feathering appeared normal regardless of treatment. Birds that received contaminated corn exhibited plaques in the mouth and gizzard erosions proportional to the level of substitution. All lesions were generally restricted to the epithelial layer and no liver or kidney involvement could be demonstrated. A short return to uncontaminated feed eliminated most lesions. Fowl appear to be considerably more tolerant of vomitoxin than swine.
mesh_terms: D000818:Animals; D001835:Body Weight; D002645:Chickens / Q000502:physiology; D004032:Diet; D004361:Drug Tolerance; D005506:Food Contamination; D005670:Fusarium / Q000254:growth & development*; D005895:Gizzard, Avian / Q000473:pathology; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D011201:Poultry Diseases / Q000139:chemically induced* / Q000473:pathology; D012717:Sesquiterpenes / Q000633:toxicity*; D014255:Trichothecenes / Q000633:toxicity*; D003313:Zea mays / Q000382:microbiology*; D015025:Zearalenone / Q000633:toxicity
chemical_list: D012717:Sesquiterpenes; D014255:Trichothecenes; D015025:Zearalenone; C007262:deoxynivalenol