title: Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide.
abstract: Severe allergic contact dermatitis from a paint mildewcide, 2-n-octyl-4-isothiazolin-3-one, developed in a worker formulating latex paints within a paint manufacturing company, Guinea pig maximization testing demonstrated this to be a moderate sensitizer. Further cases of allergic contact dermatitis may be encountered as the use of this biocide increases in the market place.
mesh_terms: D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D005659:Fungicides, Industrial / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010150:Paint / Q000009:adverse effects*; D010328:Patch Tests; D013844:Thiazoles / Q000009:adverse effects*
chemical_list: D005659:Fungicides, Industrial; D013844:Thiazoles; C035331:2-n-octyl-4-isothiazolin-3-one