Allergic dermatitis to benzyl alcohol in an injectable solution.
Benzyl alcohol produced an allergic contact dermatitis in a 46-year-old woman. The dermatitis was characterized by erythema, palpable edema, and raised borders. It had occurred after the use of sodium tetradecyl sulfate, a sclerosing agent used for the treatment of varicose veins. This article reviews the widespread use of this preservative in a variety of injectable agents.
D019905:Benzyl Alcohol; D001592:Benzyl Alcohols / Q000009:adverse effects*; D001593:Benzyl Compounds / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology*; D004487:Edema / Q000139:chemically induced; D004890:Erythema / Q000139:chemically induced; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000009:adverse effects* / Q000627:therapeutic use; D014648:Varicose Veins / Q000628:therapy
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D012597:Sclerosing Solutions; D019905:Benzyl Alcohol