title: Mechanisms of pustule formation in cutaneous bacterial and viral infections: alterations of neutrophil membrane surface receptors.
abstract: Changes in membrane surface receptors have been demonstrated by rosetting methods in polymorphonuclear leukocytes obtained from the pustules of different infectious dermatoses. There was a distinct difference in numbers of receptors in neutrophils from bacterial and viral pustules, i.e., C3b receptors were decreased on neutrophils from both bacterial and viral pustules, whereas IgG-Fc receptors were decreased only in neutrophils from viral pustules. The difference appears to be due to variations in the defence mechanisms against the invading micro-organisms.
mesh_terms: D000152:Acne Vulgaris / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology; D005499:Folliculitis / Q000276:immunology; D006562:Herpes Zoster / Q000276:immunology; D006801:Humans; D009504:Neutrophils / Q000276:immunology*; D011951:Receptors, Complement / Q000032:analysis*; D017463:Receptors, Complement 3b; D011961:Receptors, Fc / Q000032:analysis*; D012397:Rosette Formation; D012874:Skin Diseases, Infectious / Q000276:immunology*
chemical_list: D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011961:Receptors, Fc