title: Morphophysiological studies in experimental myocardial aggressions with isoproterenol. Note I. Morphological aspects.
abstract: The morphopathogenesis of lesions induced by high doses of isoproterenol injected for 1-7 days and 1-3 months is dynamically studied in groups of Wistar rats and guinea pigs. The disseminated myocardial necroses induced were of a hypoxic nature. By cicatricial substitutions, lesions of cardiosclerosis similar to those observed in pheochromocytoma cases were obtained.
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D007279:Injections, Subcutaneous; D007545:Isoproterenol / Q000008:administration & dosage* / Q000009:adverse effects; D009203:Myocardial Infarction / Q000139:chemically induced*; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D051381:Rats; D011919:Rats, Inbred Strains; D012598:Sclerosis
chemical_list: D007545:Isoproterenol