title: Malignant pleural effusion and Tc-99m MDP accumulation.
abstract: Two case reports of malignant pleural effusion from breast carcinoma, with scans showing a striking accumulation of Tc-99m MDP, are presented. The Tc-99m MDP was in the pleural fluid and not in the pleura as demonstrated by shift with gravity. Possible mechanisms of malignant effusion accumulation of Tc-99m MDP are suggested. The scant literature on the subject is reviewed.
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging; D001943:Breast Neoplasms / Q000150:complications*; D004164:Diphosphonates; D005260:Female; D006801:Humans; D008875:Middle Aged; D010710:Phosphates / Q000378:metabolism; D010996:Pleural Effusion / Q000000981:diagnostic imaging* / Q000209:etiology / Q000378:metabolism; D011187:Posture; D011877:Radionuclide Imaging; D013667:Technetium; D013669:Technetium Tc 99m Medronate
chemical_list: D004164:Diphosphonates; D010710:Phosphates; D013667:Technetium; D013669:Technetium Tc 99m Medronate