title: Chronic respiratory disease in a horse infected with Dictyocaulus arnfieldi.
abstract: A 6-year-old Thoroughbred gelding was examined because of respiratory disease that developed after it was placed on pasture occupied by a donkey. Clinical signs in the gelding included a harsh, dry paroxysmal cough and increased expiratory effort. Eosinophils were seen in smears of mucus aspirated from the trachea and the bronchi. Immature, 5th-stage Dictyocaulus arnfieldi was identified in the tracheal mucus. The cough and other clinical signs were not diminished by corticosteroid therapy or by the administration of bronchodilators. Treatment with 10-fold therapeutic dosages of thiabendazole (440 mg/kg) on each of 2 successive days resulted in permanent cessation of the clinical signs.
mesh_terms: D000818:Animals; D004022:Dictyocaulus Infections / Q000175:diagnosis* / Q000188:drug therapy; D006734:Horse Diseases / Q000175:diagnosis* / Q000188:drug therapy; D006736:Horses; D008297:Male; D012140:Respiratory Tract Diseases / Q000175:diagnosis*; D012141:Respiratory Tract Infections / Q000175:diagnosis; D013827:Thiabendazole / Q000627:therapeutic use
chemical_list: D013827:Thiabendazole