[Immunoglobulin A glomerulonephritis. Epidemiology in a population of 250 000 inhabitants].
Between April 1, 1975 and May 1, 1982, 192 cases of primary glomerulonephritis were histologically diagnosed in the Nephrology centre of a health district with 250 000 inhabitants; 58 (30.2%) of the lesions were IgA glomerulonephritis. All patients were born and lived in that district. At the end of the period under review the prevalence of IgA glomerulonephritis was evaluated at 1/10 000 and its incidence at 2.5/100 000 per year. The disease began in subjects under 35 years of age in 65% of the cases, with a peak between 16 and 25 years. Thirty-seven patients were symptom-free, and the condition was diagnosed either at recruitment in the army (15 cases; 25.2%) or during the annual medical examination of industrial workers (19 cases; 39.7%). At the end of the study, 21 patients (36%) had renal failure, and 5 of these (8.5%) were under periodical haemodialysis. This study shows how valuable it would be from a socio-economic point of view if the role played by public health institutions in detecting the disease were confirmed and if its prevalence among the French population were precisely known.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003151:Community Health Centers; D003430:Cross-Sectional Studies; D005260:Female; D005602:France; D005921:Glomerulonephritis / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
D007070:Immunoglobulin A
Glomérulonéphrite à immunoglobulines A. Epidémiologie dans une population de 250 000 habitants.