[Localization of iron and sulfur in the lysosomes of thyroid epithelium using electron probe microanalysis and X-ray spectrometry].
Thyroid lysosomes have been studied by means of EPMA combined with an electron microscope. In 4 months old mice, lysosomes are a few number and contain very low iodine concentrations and sulfur load is not significant. In 10 months old mice, iodine only or associated with sulfur is observed in homogeneous lysosomes varying in size and density. Those two types of localizations reflect two eventual steps in hormonal metabolism pathway of iodine.
D000818:Animals; D004577:Electron Probe Microanalysis / Q000379:methods; D004848:Epithelium / Q000648:ultrastructure; D007501:Iron / Q000032:analysis*; D008247:Lysosomes / Q000648:ultrastructure*; D051379:Mice; D008854:Microscopy, Electron / Q000379:methods; D013057:Spectrum Analysis / Q000379:methods; D013455:Sulfur / Q000032:analysis*; D013961:Thyroid Gland / Q000648:ultrastructure*
D013455:Sulfur; D007501:Iron
Localisation de l'iode et du soufre dans les lysosomes de l'épithélium thyroïdien en microanalyse par sonde électronique et spectrométrie des rayons X.