Severe local reactions to live measles virus vaccine following an immunization program.
A cluster of nine severe local reactions occurred in a Pennsylvania school district following a mass measles immunization program in February 1981. A case-control study showed that the nine cases had a statistically significant increased history of having received killed measles vaccine previously (p less than .001, Fisher's exact test) and a statistically significant higher geometric mean measles antibody titer (p less than .01, Student's t test) than controls, suggesting that previous receipt of killed measles vaccine was the underlying cause of these reactions.
D000293:Adolescent; D002648:Child; D003875:Drug Eruptions / Q000209:etiology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007277:Injections, Jet; D008458:Measles Vaccine / Q000009:adverse effects*
D008458:Measles Vaccine