title: Photosensitivity to musk ambrette.
abstract: Photosensitivity to musk ambrette was confirmed in 15 men previously photopatch tested and in a further 4 men currently attending the clinic. 6 of the recalled patients continued to react adversely to sunlight due either to unrecognised exposure to musk ambrette or to their having become persistent light reactors. Positive photopatch tests, possibly cross reactions, were seen in 3 of the 19 patients with the structurally-related nitromusks, moskene and musk xylene but not with musks ketone and tibetine. Musk ambrette elicited a positive patch test without light in 3 of the 19 patients.
mesh_terms: D000152:Acne Vulgaris / Q000139:chemically induced; D000328:Adult; D000368:Aged; D055598:Chemical Phenomena; D002621:Chemistry; D004136:Dinitrobenzenes / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007189:Indans / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009574:Nitro Compounds / Q000009:adverse effects; D009578:Nitrobenzenes / Q000009:adverse effects*; D010328:Patch Tests; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013472:Sunlight / Q000009:adverse effects; D014992:Xylenes / Q000009:adverse effects
chemical_list: D004136:Dinitrobenzenes; D007189:Indans; D009574:Nitro Compounds; D009578:Nitrobenzenes; D014992:Xylenes; C042842:musk tibetine; C042841:moskene; C031447:musk xylene; C031448:musk ketone; C020422:musk ambrette (artificial)