title: [Intensified virulence of the causative agent in the process of the formation of a focus of cutaneous leishmaniasis].
abstract: A possible effect of a new epidemic nidus "age" on the virulence of Leishmania was studied. For a period of 9 years 16 strains were isolated from man affected with leishmaniosis. Infectivity of all strains was high (100% infection of animals). The incubative period of the disease in animals was the shorter the more years passed from the moment of the nidus formation. Strains isolated within the first 4-5 years caused leishmaniosis in 2-3 months and those isolated during subsequent years--in 1 to 3 weeks.
mesh_terms: D000818:Animals; D004197:Disease Reservoirs; D005849:Gerbillinae; D006801:Humans; D007623:Kazakhstan; D007891:Leishmania / Q000302:isolation & purification / Q000472:pathogenicity*; D007896:Leishmaniasis / Q000469:parasitology*; D051379:Mice; D013997:Time Factors; D014774:Virulence
vernacular_title: Usilenie virulentnosti vozbuditelia v protsesse stanovleniia ochaga kozhnogo leĭshmanioza.