[Fatal bee sting: 1st report of IgG4-mediated anaphylactic shock].
The author reports on a 39 year-old male patient with allergic asthma who died several hours after a bee sting in a state of shock. While IgE antibodies were not present, distinct deposits of IgG4 antibodies in the kidney and lung were demonstrated for the first time after a bee sting. The intention of this report is to stress the importance of hyposensibilisation of patients with an allergic condition after determination of the relevant class or subclass of immunoglobulins.
D000328:Adult; D000707:Anaphylaxis / Q000209:etiology / Q000276:immunology*; D000906:Antibodies / Q000032:analysis; D001516:Bees; D001929:Brain Edema / Q000209:etiology; D006332:Cardiomegaly / Q000209:etiology; D003888:Desensitization, Immunologic; D006801:Humans; D006967:Hypersensitivity / Q000628:therapy; D007074:Immunoglobulin G / Q000145:classification / Q000276:immunology*; D007299:Insect Bites and Stings / Q000150:complications / Q000276:immunology*; D007819:Laryngeal Edema / Q000209:etiology; D008297:Male; D011654:Pulmonary Edema / Q000209:etiology
D000906:Antibodies; D007074:Immunoglobulin G
Tod nach Bienenstich: Erstmaliger Nachweis eines IgG4-mediierten anaphylaktischen Schocks.