Immune-mediated vasculitis in five dogs.
Vasculitis was diagnosed in 5 dogs. Clinical signs varied, but all 5 dogs had signs of systemic illness. Inflammation and fibrinoid necrosis of small blood vessels were consistent findings. The skin and mucous membranes were the main tissues involved in 3 dogs; polyarthropathy and myopathy were diagnosed in 1 dog and myopathy in 1 dog. Good response to corticosteroid therapy was achieved in 3 dogs; in 2 dogs, immunosuppressive therapy with cyclophosphamide was necessary and the dogs responded well.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology; D004283:Dog Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004285:Dogs; D005260:Female; D007105:Immune Complex Diseases / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D014657:Vasculitis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*
D000936:Antigen-Antibody Complex