title: Establishment of a system suitable for analysis of balanced and unbalanced growth of Streptomyces hygroscopicus.
abstract: A small-scale system was developed in which balanced growth of Streptomyces hygroscopicus occurred. Although the balanced growth, verified by corresponding increase of ATP, DNA, RNA, protein and mycelial length, was restricted to a relatively short period of the life cycle, it lasted for at least two doublings. The conditions for balanced growth could be altered by various treatments to induce imbalance. This system could be applied to study regulation in the mycelium under well-defined conditions.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism; D003470:Culture Media; D004269:DNA, Bacterial / Q000378:metabolism; D008757:Methylglucosides / Q000494:pharmacology; D012329:RNA, Bacterial / Q000378:metabolism; D013171:Spores, Bacterial; D013302:Streptomyces / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D004269:DNA, Bacterial; D008757:Methylglucosides; D012329:RNA, Bacterial; C027020:methylglucoside; D000255:Adenosine Triphosphate