Protection against Pasteurella pneumotropica during infection with Angiostrongylus cantonensis.
Lung infections of specific-pathogen-free rats were studied to determine cross-immunity between infections with Pasteurella pneumotropica and Angiostrongylus cantonensis. Rats were found to have differences in mortality due to pneumonic infections with P pneumotropica and A cantonensis and to coinfections of P pneumotropica and A cantonensis. Single infections of P pneumotropica were not dosage-dependent in their lethality for specific-pathogen-free rats. The mortality of coinfection with P pneumotropica and A cantonensis was significantly lower than that of a monoinfection with P pneumotropica, demonstrating a cross-protective phenomenon.
D000801:Angiostrongylus; D000818:Animals; D001996:Bronchopneumonia / Q000276:immunology / Q000662:veterinary; D008168:Lung / Q000276:immunology; D009349:Nematode Infections / Q000276:immunology / Q000662:veterinary*; D010326:Pasteurella Infections / Q000276:immunology / Q000662:veterinary*; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000276:immunology*; D013047:Specific Pathogen-Free Organisms