[Behavior of blood values of prolactin, TSH, FSH, and LH in gastroduodenal ulcer during drug therapy].
A study has been carried out on 20 male patients affected by gastric and duodenal ulcer disease and undergoing pharmacological treatment with pirenzepine, cimetidine, carbenoxolone and zolimidine in a multicentre controlled clinical trial, on PRL, TSH, FSH, LH plasma levels, taking into account the circadian rhythms of these endocrine variables. Basal and follow-up tests have been carried out, as well as a stimulation tests with TRH and LHRH. The findings do not allow for definite conclusions: two patients have shown moderate increases in the PRL levels after cimetidine; all patients have shown optimum responses to the stimulation test.
D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001570:Benzodiazepinones / Q000627:therapeutic use; D002229:Carbenoxolone / Q000627:therapeutic use; D002927:Cimetidine / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000097:blood / Q000188:drug therapy*; D010890:Pirenzepine; D011388:Prolactin / Q000097:blood*; D011725:Pyridines / Q000627:therapeutic use; D013972:Thyrotropin / Q000097:blood*
D000897:Anti-Ulcer Agents; D001570:Benzodiazepinones; D011725:Pyridines; D010890:Pirenzepine; D002927:Cimetidine; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D002229:Carbenoxolone
Osservazioni sul comportamento dei valori ematici di PRL, TSH, FSH, LH NELLA malattia ulcerosa gastro-duodenale in trattamento farmacologico.