title: Modulation of IgE response by phytohemagglutinin.
abstract: The effect of the administration of phytohemagglutinin (PHA) on the IgE response was studied. RF mice were immunized with OA in aluminum hydroxide gel and PHA was injected 1 or 2 days before the immunization in doses of 80 or 1 microliter. Results show that PHA injected on day -1 induces suppression and PHA administered on day -2 induces some stimulation in the IgE response. This effect is independent of the PHA doses used and does not affect the anti-OA hemagglutinin production.
mesh_terms: D000818:Animals; D007115:Immunization Schedule; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007279:Injections, Subcutaneous; D051379:Mice; D010835:Phytohemagglutinins / Q000008:administration & dosage*; D051381:Rats; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013997:Time Factors
chemical_list: D010835:Phytohemagglutinins; D007073:Immunoglobulin E