title: The treatment of onychomycosis with miconazole tincture.
abstract: Treatment of onychomycosis is usually unsatisfactory. A small clinical trial using a solution of miconazole (Daktarin; Janssen) in alcohol was undertaken to assess its potential in this difficult condition. Ten unselected patients completed the 32-week trial and the results, irrespective of whether the infecting organism was fungal or monilial, are recorded. A much larger and controlled trial is essential before firm conclusions may be drawn, but the results, particularly in Candida infections, are encouraging.
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D002177:Candidiasis / Q000188:drug therapy; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy; D006229:Hand Dermatoses / Q000188:drug therapy; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D008297:Male; D008825:Miconazole / Q000008:administration & dosage*; D008875:Middle Aged; D014009:Onychomycosis / Q000188:drug therapy*; D012996:Solutions; D014005:Tinea / Q000188:drug therapy
chemical_list: D007093:Imidazoles; D012996:Solutions; D008825:Miconazole