Effects of vitamin E on mixed lymphocyte cultures.
When lymphocytes from individuals ingesting vitamin E were used as responding cells in the mixed lymphocyte culture (MLC) the proliferative response was normal indicating that T lymphocyte reactivity to allogeneic antigen was undisturbed. However, the use of lymphocytes from individuals receiving vitamin E as stimulating cells in the MLC resulted in a diminished proliferative response suggesting that large doses of vitamin E may effect B cells and/or macrophages as they interacted with T lymphocytes.
D000328:Adult; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D013601:T-Lymphocytes / Q000187:drug effects*; D014810:Vitamin E / Q000494:pharmacology*
D014810:Vitamin E