title: [Effect of the polymerase activity of DNA polymerase I on the development of the temperate bacteriophages Mu, lambda red- and lambda red-gam-. I. The effect of the polymerase activity of DNA polymerase I on the development of bacteriophages lambda red- and lambda red-gam-].
abstract: Phages lambda c1857 red3 and lambda bio10 in Escherichia coli K-12 cells with impaired function of DNA-polymerase I polymerizing activity are shown to restore their normal development level when exonucleases V and I are removed from cells. In other words, an indirect involvement of DNA-polymerase I in the development of phages lambda defective in general recombination systems and gene gam functions has been established. A probability of DNA-polymerase I participation in the recombination stage of phage lambda development in E. coli K-12 cells is discussed.
mesh_terms: D000327:Adsorption; D010582:Bacteriophage lambda / Q000235:genetics*; D003227:Conjugation, Genetic; D004256:DNA Polymerase I / Q000235:genetics*; D003673:Defective Viruses / Q000235:genetics; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D008242:Lysogeny; D011995:Recombination, Genetic; D014161:Transduction, Genetic
chemical_list: D004256:DNA Polymerase I
vernacular_title: Vliianie polimeraznoĭ aktivnosti DNK-polimerazy I na razvitie umerennykh bakteriofagov Mu, lambda red-, lambda red-gam-. Soobshchenie I. Vliianie polimeraznoĭ aktivnosti DNK-polimerazy I na razvitie bakteriofagov lambda red-, lambda red-gam-.