title: Design of controlled clinical trials: use of historical controls.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic / Q000379:methods*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005910:Glioma / Q000188:drug therapy; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D008297:Male; D008926:Plicamycin / Q000627:therapeutic use; D011897:Random Allocation; D014498:Uracil / Q000031:analogs & derivatives / Q000627:therapeutic use; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003561:Cytarabine; D014498:Uracil; D014750:Vincristine; D003520:Cyclophosphamide; C100248:azauracil; D008926:Plicamycin; D003630:Daunorubicin