title: [Pathomorphologic characteristics of esophageal biopsies among inhabitants of an endemic focus of cancer of the esophagus].
abstract: The data on the frequency and topography of pathological processes in esophageal mucosa in residents of a focus endemic for esophageal cancer are presented on the basis of 1017 esophageal biopsies analysed in the Guriev regional oncological hospital in 1977-1982. Three groups of pathology were distinguished: esophagites (37.3 +/- 1.5%), precancer (21.6 +/- 1.3%), and cancer (41.1 +/- 1.5%). Chronic forms of esophagites were predominant (83.1%). In the precancer group, leukoplakias comprised 62.3%. Invasive forms were observed in 92.6% of all cases of esophageal cancer. Chronic esophagites represent an unfavourable background for the development of precancer changes and cancer.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D000368:Aged; D001706:Biopsy; D002278:Carcinoma in Situ / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D004938:Esophageal Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control*; D004941:Esophagitis / Q000473:pathology; D004947:Esophagus / Q000473:pathology; D005006:Ethnicity; D005260:Female; D006801:Humans; D007623:Kazakhstan; D007971:Leukoplakia / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology
vernacular_title: Patomorfologicheskaia kharakteristika ézofagobioptatov u zhiteleĭ ochaga, éndemichnogo po raku pishchevoda.