Nuclear magnetic resonance and transcutaneous electromagnetic blood flow measurement.
Static and alternating magnetic fields are employed in blood flowmeters using nuclear magnetic resonance (NMR) principles and electromagnetic induction by a moving conductor (TEM). Both techniques require high steady magnetic fields, obtained either from permanent magnets or from electromagnets. A relatively homogeneous magnetic field is needed for NMR, but, though important for calibration, homogeneity is not critical for TEM. NMR is more complex than TEM since it requires radio-frequency and audio-frequency magnetic fields. However, the TEM method requires surface electrodes in contact with the skin, or needle electrodes placed subcutaneously, whereas NMR is contactless. The NMR flowmeter can be calibrated directly, but appropriate and approximate models must be assumed and then solved by computer to quantify blood flow by the TEM flowmeter. Flow in individual vessels is measured a priori in the TEM flowmeter by virtue of the assumed models. To measure flow in individual vessels by NMR, a scanning or ranging method is required, which logically leads to blood flow imaging. The levels of steady, radio-frequency, and audio-frequency magnetic fields used in the two types of flowmeters are low enough so as not to cause any apparent stimulus to human volunteers and patients tested.
D000328:Adult; D001132:Arm / Q000098:blood supply; D001157:Arterial Occlusive Diseases / Q000175:diagnosis; D001783:Blood Flow Velocity; D001916:Brachial Artery; D002339:Carotid Arteries; D055590:Electromagnetic Phenomena; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply; D009682:Magnetic Resonance Spectroscopy; D008433:Mathematics; D008953:Models, Anatomic; D011150:Popliteal Artery; D012212:Rheology