On regional mapping of human chromosome 6. Review and own findings.
In addition to the committee Reports on the Constitution of Chromosome 6 also the mapping contributions from patients with no. 6 imbalances were added to the scheme. Moreover own PGM 3 : GLO : HLA linkage data are given. The controversially discussed gene order of these three loci was analysed from appropriate backcross families. The most likely gene order is HLA-A, C, B : BF (C2, C4) : HLA-D/DR : GLO (all at about 6p 21-p22) : 6 ph (centromer) : PGM3 (6q12): ME 1 (6q12-q15) : SOD 2 (6q21).
D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D005802:Genes, MHC Class II; D008040:Genetic Linkage; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008190:Lyases / Q000235:genetics*; D010733:Phosphoglucomutase / Q000235:genetics*
D005819:Genetic Markers; D006680:HLA Antigens; D015234:HLA-A Antigens; D008190:Lyases; D007791:Lactoylglutathione Lyase; D010733:Phosphoglucomutase