title: Effect of prolactin inhibition by bromocriptine on testicular metabolism in the adult rat.
abstract: Administration of bromocriptine resulted in a decrease of testicular tissue somatic index, total, structural and soluble protein concentrations. The catabolic phase of carbohydrate metabolism was enhanced. Consequently, the required metabolites for increased citric acid cycle activity were provided by increased glycolytic activity. The pre-requisite metabolites needed for spermatogenic processes were accumulated in the testis, due to their non-utilization. The results obtained suggest a specific influence of prolactin inhibition on testicular metabolism in the adult rat.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009243:NAD / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D011388:Prolactin / Q000037:antagonists & inhibitors*; D051381:Rats; D011919:Rats, Inbred Strains; D012794:Sialic Acids / Q000378:metabolism; D013737:Testis / Q000187:drug effects / Q000378:metabolism*
chemical_list: D012794:Sialic Acids; D009243:NAD; D001971:Bromocriptine; D011388:Prolactin; D010088:Oxidoreductases; C022691:succinate oxidase; D007770:L-Lactate Dehydrogenase; D000251:Adenosine Triphosphatases