Oligomycin sensitivity-conferring protein (OSCP) of beef heart mitochondria. Internal sequence homology and structural relationship with other proteins.
Structural analysis of oligomycin sensitivity-conferring protein (OSCP) revealed repeating sequences (residues 1-89, 105-190) suggesting an evolution of the protein by gene duplication. In addition to the reported homology with the delta-subunit of Escherichia coli F1ATPase, OSCP also shows a certain homology with the b-subunit of E. coli F0 and the ADP/ATP carrier of mitochondria.
D000251:Adenosine Triphosphatases / Q000302:isolation & purification*; D000595:Amino Acid Sequence; D000818:Animals; D002352:Carrier Proteins / Q000302:isolation & purification*; D002417:Cattle; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000302:isolation & purification*; D008929:Mitochondria, Heart / Q000378:metabolism*; D000226:Mitochondrial ADP, ATP Translocases; D025261:Mitochondrial Proton-Translocating ATPases; D012984:Software; D013329:Structure-Activity Relationship
D002352:Carrier Proteins; D046911:Macromolecular Substances; D008565:Membrane Proteins; D000226:Mitochondrial ADP, ATP Translocases; D000251:Adenosine Triphosphatases; D025261:Mitochondrial Proton-Translocating ATPases; C020439:oligomycin sensitivity-conferring protein