Optic neuropathy and cerebral sarcoidosis.
An intracranial mass lesion is a rare, but reported presenting sign in sarcoidosis. A 39-year-old woman presented with a frontal lobe lesion (pathologically a noncaseating granuloma) associated with chronic progressive visual loss and optic atrophy on the right side. High-resolution axial and coronal computerized tomography revealed a parachiasmal density compatible with the clinical course. Clinical suspicion of granulomatous processes and appropriate workup in all cases of optic neuropathy may allow for early medical therapy in such cases.
D000328:Adult; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006099:Granuloma / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D009896:Optic Atrophy / Q000000981:diagnostic imaging / Q000209:etiology*; D009897:Optic Chiasm; D012507:Sarcoidosis / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000209:etiology*