Cation permeability induced by two 15-O5 macrocyclic polyether carriers in phospholipidic large unilamellar vesicles.
Sodium permeability in phospholipidic large unilamellar vesicles induced by two 15-O5 macrocyclic polyether derivatives, a carboxylic one 1a and a neutral one 1b, has been studied. The neutral derivative, 1b, appears to behave as a classical mobile carrier such as valinomycin and the carboxylic carrier, 1a, as an ionophore of the nigericin group.
D002784:Cholesterol; D004988:Ethers, Cyclic; D007700:Kinetics; D008954:Models, Biological; D010539:Permeability; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D012964:Sodium; D013329:Structure-Activity Relationship
D004988:Ethers, Cyclic; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D002784:Cholesterol; D012964:Sodium