Lymphocyte subpopulations in patients with acne vulgaris.
T- and B-lymphocyte subpopulations were measured in the peripheral blood of patients with varying severity of acne and in acne-free control subjects. Increased severity of acne correlated with an increased number of T lymphocytes, helper T cells and B cells, while the number of suppressor T cells remained normal and did not alter significantly. This evidence suggests that there is no lack of regulation of the immune response in acne patients.
D000152:Acne Vulgaris / Q000097:blood* / Q000276:immunology; D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology