title: Pulmonary veno-occlusive disease in an elderly man: case report and review of the literature.
abstract: A 75-year-old man complaining of dyspnea and having sings of postcapillary pulmonary hypertension was diagnosed as pulmonary veno-occlusive disease and confirmed at autopsy. This is the oldest case ever reported. Almost all the small veins 2 mm or less in external diameter were partially or nearly completely occluded by intimal fibrous tissue, and the obstructive changes in the pulmonary arteries were much more limited. Pulmonary veno-occlusive disease is a rare, almost inevitably fatal disease of unknown etiology which has only recently been separated clearly from primary pulmonary hypertension as a distinct entity. Chest roentgenogram finding suggesting postcapillary pulmonary hypertension is a clue to a diagnosis and differentiates this from two other causes of clinical primary pulmonary hypertension, that is, recurrent pulmonary embolism and plexogenic pulmonary arteriopathy.
mesh_terms: D000368:Aged; D003011:Closing Volume; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D010366:Peak Expiratory Flow Rate; D011379:Prognosis; D011667:Pulmonary Veins / Q000473:pathology; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013318:Stroke Volume; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D013927:Thrombosis / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D014109:Total Lung Capacity; D014797:Vital Capacity
chemical_list: D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium