[Comparison of the antiphlogistic effect of mucopolysaccharide-polysulfate ointments with heparin-containing ointments in the UV erythema test].
It could be demonstrated by means of the UV erythema model that four different ointment preparations containing mucopolysaccharide polysulfate (MPS) have a marked antiinflammatory effect and inhibit the formation of erythemas to a large extent. In this trial arrangement the different preparations containing MPS were significantly superior to altogether eight commercial heparin ointments, which were tested, too. With an inhibition of 69% of the erythema induced by UV rays, Hirudoid 40000 ointment is the most effective of all preparations tested.
D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D004890:Erythema / Q000188:drug therapy* / Q000209:etiology; D006025:Glycosaminoglycans / Q000627:therapeutic use*; D006168:Guinea Pigs; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use*; D009824:Ointments; D013464:Sulfuric Acids / Q000627:therapeutic use; D014466:Ultraviolet Rays
D000893:Anti-Inflammatory Agents; D006025:Glycosaminoglycans; D009824:Ointments; D013464:Sulfuric Acids; D006493:Heparin
Vergleich der antiphlogistischen Wirkung von Mucopolysaccharid-polyschwefelsäureester-Salben mit heparinhaltigen Salben im UV-Erythem-Test.