Anthelmintic activities of ivermectin against immature and adult Dictyocaulus viviparus.
Eighteen calves about 3 months old were inoculated with 3,000 Dictyocaulus viviparus infective larvae. Three groups of 6 calves each were formed. Thirteen days after inoculations, 3 of the 6 group 1 control calves were given vehicle subcutaneously (SC) and the group 2 calves were given ivermectin at the dose rate of 200 micrograms/kg, SC. Thirty-five days after inoculation, the remaining 3 calves in group 1 were given vehicle SC and the group 3 calves were given ivermectin at the dose rate of 200 micrograms/kg, SC. Necropsies were performed 42 days after inoculations. A total of 474 D viviparus was recovered from the group 1 control calves, whereas none was recovered from the calves treated when the nematodes were in the 4th stage of development (group 2) or adult stage (group 3).
D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000469:parasitology; D004021:Dictyocaulus / Q000187:drug effects*; D004022:Dictyocaulus Infections / Q000188:drug therapy* / Q000469:parasitology; D005243:Feces / Q000469:parasitology; D007559:Ivermectin; D007783:Lactones / Q000008:administration & dosage / Q000627:therapeutic use*; D008681:Metastrongyloidea / Q000187:drug effects*
D000871:Anthelmintics; D007783:Lactones; D007559:Ivermectin