Cardiac hypertrophy: biochemical and cellular relationships.
Cardiac hypertrophy can be looked at in several ways. Clinicians are concerned with the limits of adaptation to hemodynamic overload. Biologists seek to delineate the mechanisms that regulate synthesis of cellular components to meet functional demands. Understanding of the genetic mechanisms that control synthesis of cardiac protein could have clinical significance.
D000818:Animals; D006332:Cardiomegaly / Q000378:metabolism / Q000503:physiopathology*; D002455:Cell Division; D004247:DNA / Q000096:biosynthesis; D004734:Energy Metabolism; D005786:Gene Expression Regulation; D006321:Heart / Q000254:growth & development / Q000503:physiopathology; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D008929:Mitochondria, Heart / Q000378:metabolism; D009200:Myocardial Contraction; D009206:Myocardium / Q000166:cytology / Q000378:metabolism; D009218:Myosins / Q000378:metabolism; D051381:Rats
D007527:Isoenzymes; D004247:DNA; D009218:Myosins