Orbitocalvarial swelling and proptosis as an early manifestation of systemic lymphoma.
A 67-year-old woman had acutely diminished vision and painful proptosis of the left eye amidst a background of chronic headache, scalp tenderness, proximal myalgias, intermittent fever, anemia, and elevated erythrocyte sedimentation rates. All symptoms and signs were exquisitely corticosteroid-responsive. She underwent two negative temporal artery biopsies and several extensive negative evaluations for systemic disease. Ultimately deep scalp biopsy, bone biopsy, and bone marrow aspiration were performed, and all revealed a histologically well-differentiated lymphoma.
D000368:Aged; D001706:Biopsy; D001847:Bone Diseases / Q000209:etiology; D001842:Bone and Bones / Q000473:pathology; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D009916:Orbital Diseases / Q000209:etiology*; D012535:Scalp / Q000473:pathology; D012886:Skull