title: [Various results and prospective trends in research on the immunology of spinal osteochondrosis with neurologic disorders].
abstract: The authors review the results of many-year studies concerning the immunological aspects of the pathogenesis of the peripheral nervous system involvement in osteochondrosis of the lumbar division of the vertebral column. On the basis of a great body of information a complex study of the role of humoral factors in the natural specific immunity, as well as the state of the T- and B-systems of immunity in patients with the non-radical and radical stages of the lumbar osteochondrosis was for the first time undertaken. The results obtained point to the participation of all the immunity links in the disease pathogenesis. This is an important prerequisite for the search for purposeful pathogenetic therapy of this widespread disease.
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D001416:Back Pain / Q000276:immunology; D006801:Humans; D007403:Intervertebral Disc; D007958:Leukocyte Count; D010007:Osteochondritis / Q000276:immunology*; D010146:Pain; D011843:Radiculopathy / Q000276:immunology; D013122:Spinal Diseases / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000936:Antigen-Antibody Complex; D001323:Autoantibodies
vernacular_title: Nekotorye itogi i perspektivnye napravleniia v izuchenii immunologii osteokhondroza pozvonochnika s nevrologicheskimi narusheniiami.