[The succession of precocious puberty and Stein-Leventhal syndrome].
The authors relate the observation of a girl with precocious puberty diagnosed at 4 years, treated for 7 years with medroxyprogesterone and who presents now a Stein-Leventhal syndrome. They emphasize the unique character of this association and discuss the different pathogenetic hypotheses: hypothalamo-pituitary disorder, effect of medroxyprogesterone acetate, hyperinsulinism, casual association.
D000735:Androstenedione / Q000378:metabolism; D002675:Child, Preschool; D003687:Dehydroepiandrosterone / Q000378:metabolism; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D008525:Medroxyprogesterone / Q000009:adverse effects / Q000627:therapeutic use; D011085:Polycystic Ovary Syndrome / Q000139:chemically induced / Q000150:complications* / Q000503:physiopathology; D011374:Progesterone / Q000378:metabolism; D011629:Puberty, Precocious / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D013739:Testosterone / Q000378:metabolism
D013739:Testosterone; D000735:Androstenedione; D003687:Dehydroepiandrosterone; D011374:Progesterone; D008525:Medroxyprogesterone; D006854:Hydrocortisone
Succession puberté précoce et syndrome de Stein-Leventhal.