Antibody response to pneumococcal vaccine in patients with trisomy-21 (Down's syndrome).
The antibody response to pneumococcal vaccine was lower in adults with trisomy-21 (Down's syndrome) than in controls. Males gave lower response than females, significantly so among the 21-trisomic patients. The antibody response to different polysaccharides differed between the groups.
D000328:Adult; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D004314:Down Syndrome / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011135:Polysaccharides, Bacterial / Q000276:immunology; D012737:Sex Factors; D013296:Streptococcus pneumoniae / Q000276:immunology*; D014611:Vaccination
D000907:Antibodies, Bacterial; D011135:Polysaccharides, Bacterial