title: Computer assisted small-scale Tay-Sachs carrier screening.
abstract: Fluorescence data from serum beta-hexosaminidase assays for Tay-Sachs heterozygote screening is processed by a program in BASIC for a Wang 2200 desk-top computer. An estimation of overall error in the results gives a measure of reliability. A preliminary classification is made on the clinical status of the unknown samples as a normal, heterozygous, homozygous, or inconclusive carrier/normal condition. This program allows a small-scale screening center convenient and rapid data processing and analysis.
mesh_terms: D004796:Clinical Enzyme Tests; D003936:Diagnosis, Computer-Assisted; D006580:Genetic Carrier Screening; D006596:Hexosaminidases / Q000097:blood; D006801:Humans; D012984:Software; D013661:Tay-Sachs Disease / Q000175:diagnosis / Q000235:genetics*; D001619:beta-N-Acetylhexosaminidases
chemical_list: D006596:Hexosaminidases; D001619:beta-N-Acetylhexosaminidases