title: Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in gum arabic.
abstract: Benzisothiazolin-3-one is a preservative widely used in industry. The manufacturer states that it is a known skin irritant and sensitiser, but these facts are not well-known. A case is described of contact allergy in a lithoprinter caused by it when used as a preservative in gum arabic. The literature is reviewed and a suitable patch-test concentration is suggested. It should be included in the patch-test battery for lithoprinters.
mesh_terms: D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D006170:Gum Arabic; D006229:Hand Dermatoses / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011134:Polysaccharides; D011327:Printing; D013844:Thiazoles / Q000009:adverse effects*
chemical_list: D011134:Polysaccharides; D013844:Thiazoles; D006170:Gum Arabic; C015699:1,2-benzisothiazoline-3-one