Isolation and nucleotide sequence of a cloned cardionatrin cDNA.
A cloned cDNA which codes for the C-terminal 62 residues of the precursor molecule for the atrial natriuretic factor, cardionatrin, has been isolated and sequenced. The nucleotide sequence confirms the amino acid sequence of cardionatrin 1-28 previously determined, and positions this peptide at the C-terminal end of the precursor just two residues away from the termination codon.
D000595:Amino Acid Sequence; D000818:Animals; D009320:Atrial Natriuretic Factor; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification*; D006325:Heart Atria / Q000378:metabolism; D006352:Heart Ventricles / Q000378:metabolism; D008297:Male; D009124:Muscle Proteins / Q000235:genetics*; D009206:Myocardium / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D051381:Rats; D011919:Rats, Inbred Strains
D009124:Muscle Proteins; D009320:Atrial Natriuretic Factor; D004247:DNA