Factor VIII-related antigen and procoagulant activity in manic-depressive patients.
Factor VIII-related antigen (VIIIR:AG) and procoagulant activity (VIII:C) were measured at weekly intervals in 11 manic-depressive patients during their hospital stay. There were significant correlations between VIII:C (P less than 0.02), VIIIR:AG (P less than 0.05) and the number of hospital admissions over a 10-year period. The patients' VIIIR:AG showed a wider range of results as compared to a control group (P less than 0.01). The age of onset of the disease (but not the age of the patient) was related to VIIIR:AG (P less than 0.02).
D000328:Adult; D000367:Age Factors; D000941:Antigens / Q000032:analysis*; D001714:Bipolar Disorder / Q000097:blood*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008875:Middle Aged; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII