[Disordered meiosis in sterile male mice in a Lati:CFLP colony].
The incidence rate of sterile male mice in a Lati:CFLP colony was studied. It was established to amount to 0.33 +/- 011%. Part of sterile males (about 64%) had reduced weight testicles. Cytological analysis revealed spermatogenesis blockade because of spermatocyte death in the late prophase and metaphase I meiosis in these animals. It is concluded that in the mouse colony under study, genetic factor (chromosome rearrangement or gene mutation) is maintained, which determines meiosis blockade in male mice-bearers of this factor.
D000818:Animals; D001947:Breeding; D002869:Chromosome Aberrations; D007248:Infertility, Male / Q000235:genetics / Q000473:pathology*; D008297:Male; D008540:Meiosis; D051379:Mice; D009154:Mutation; D009929:Organ Size; D013047:Specific Pathogen-Free Organisms; D013090:Spermatocytes / Q000473:pathology; D013091:Spermatogenesis; D013737:Testis / Q000473:pathology
Narushenie meĭoza u besplodnykh samtsov mysheĭ kolonii Lati:CFLP.