title: Sensitive high-performance liquid chromatographic method for the determination of etodolac in serum.
abstract: A sensitive high-performance liquid chromatographic method for the determination of etodolac in serum was developed. The limit of detection was 0.2 microgram/ml. The specificity of the method was demonstrated by the lack of response obtained with a variety of control sera, sera spiked with etodolac congeners, and sera obtained from rats treated with a variety of other drugs.
mesh_terms: D000085:Acetates / Q000097:blood*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D017308:Etodolac; D006801:Humans; D013045:Species Specificity
chemical_list: D000085:Acetates; D017308:Etodolac