title: Nonimmune fetal hydrops and Down syndrome.
abstract: Six infants with nonimmune fetal hydrops (NIFH) were found to have trisomy 21 (Down syndrome). A cardiac malformation was present in three of these infants. The manifestations of Down syndrome was obscured by the generalized edema at birth. The association of Down syndrome and NIFH emphasizes the need for chromosome analysis in the workup of infants or fetuses with NIFH.
mesh_terms: D004314:Down Syndrome / Q000150:complications*; D004487:Edema / Q000150:complications* / Q000235:genetics; D005260:Female; D005315:Fetal Diseases / Q000150:complications*; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy