[Effect of imidazole on the trabecular bone volume of rats with calcium deficiency].
Low-calcium diet induces bone rarefaction in young rats by decreasing trabecular bone volume without any mineralization's defect. Given alone, calcium or imidazol increases, significantly but incompletely, trabecular bone volume. Given together, calcium and imidazol increase trabecular bone volume as well as normal diet does. These results indicate that imidazol acts likely by activating metabolic effects of calcium.
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects* / Q000473:pathology; D002118:Calcium / Q000172:deficiency* / Q000378:metabolism / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D007093:Imidazoles; C029899:imidazole; D002118:Calcium
Action de l'imidazole sur le volume trabéculaire osseux du rat carencé en calcium.