title: Patch testing with hexavalent chromium salts in different vehicles and with nickel and cobalt in petrolatum.
abstract: In approaching the question as to which test preparations are most suitable for patch testing of metals, 25 chromium sensitive patients were tested with 0.5% potassium dichromate either in water or petrolatum. The aqueous solution proved better than the petrolatum preparation at a 48 h reading with Neodermtest Roc. No difference in sensitivity was recorded between 4 hexavalent chromium salts. 3 patients who were only sensitive to chromium solution in water also reacted positively to a 1% cobalt chloride solution and a 5% nickel sulfate solution in petrolatum.
mesh_terms: D000328:Adult; D002840:Chromates / Q000276:immunology; D002857:Chromium / Q000276:immunology*; D003035:Cobalt / Q000276:immunology*; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000276:immunology*; D004485:Eczema / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D009532:Nickel / Q000276:immunology*; D010328:Patch Tests / Q000379:methods*; D014677:Pharmaceutical Vehicles; D011192:Potassium Dichromate / Q000276:immunology; D012882:Skin Tests / Q000379:methods*
chemical_list: D002840:Chromates; D014677:Pharmaceutical Vehicles; D002857:Chromium; D003035:Cobalt; D009532:Nickel; D011192:Potassium Dichromate