Electrophysiological characteristics of reticulospinal neurones in relation to the conduction velocity of their axons.
Activity was recorded intracellularly from the bodies of 87 reticulospinal neurones in the cat's gigantocellular nucleus, whose axons had a conduction velocity of 18-148 m.s-1. Slow-conducting neurones (18-45 m.s-1, 23%) were characterized by a wider action potential, higher input resistance (3.8-7.0 M omega) and a lower rheobase (1.0-1.7 nA). They were also very sensitive to changes in membrane polarity and generated regular rhythmic activity. Fast-conducting neurons (45-148 m.s-1) were characterized by a short action potential, low input resistance (0.7-2.9 M omega) and a higher rheobase (1.5-5.2 nA). When depolarizing current pulses were applied, they generated responses with action potentials with a high frequency, especially in the initial phase of depolarization, but their thresholds for the initiation of activity and steady firing were higher than in the case of slow neurones. Slow reticulospinal neurones always responded to stimulation of the spinal funiculi (mainly the dorsal funiculus) by a characteristic large postsynaptic potential on which large numbers of spike potentials were superimposed and which did not occur in fast neurones. The differences observed in membrane properties and in the character of generation of action potentials draw attention to the phasic character of fast, and the tonic character of slow, reticulospinal neurones.
D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000502:physiology*; D002415:Cats; D004553:Electric Conductivity; D004594:Electrophysiology; D007700:Kinetics; D009474:Neurons / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*; D013569:Synapses / Q000502:physiology