title: [Bolus geometry and dynamics after intravenous injections of contrast media Studies using chronography].
abstract: Studies of contrast bolus geometry and dynamics were carried out by means of a chronogram - a digital serial radiographic method. Four situations were considered - contrast volume, speed of injections, subsequent saline injections and rapidly repeated contrast boli. Peak values, maximum duration and half-life of the bolus and maximum contrast enhancement were recorded. The results have shown that a larger volume of contrast with reduced injection speed leads to a lengthening of the peak period. More rapid injection speed up to 8 ml/sec leads to a higher peak and increased contrast enhancement. Further increases of injection  speed beyond 8 ml/sec does not further increase contrast enhancement. The subsequent injection of saline has no recognisable effect on bolus geometry or dynamics.
mesh_terms: D000328:Adult; D001027:Aortography / Q000379:methods*; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine; D006801:Humans; D007275:Injections, Intravenous; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003973:Diatrizoate; D003974:Diatrizoate Meglumine
vernacular_title: Bolusgeometrie und -dynamik nach intravenöser Kontrastmittelinjektion. Studien mit Hilfe der Chronographie.