title: An epidemiologic study of the respiratory effects of trona dust.
abstract: Trona (sodium sesquicarbonate) is mined from an underground deposit in Wyoming and processed for use in glass, paper, detergent, and chemical applications. Trona dust is alkaline (pH 10.5) and can have an irritant effect on respiratory airways, mucous membranes, and the skin. A study population of 142 underground miners and 88 surface workers from one facility volunteered for an epidemiologic study. Their mean age was 37.6 yr and mean duration of employment was 10.0 yr. The percentage with chronic cough and phlegm was 23%; both symptoms were more common among smokers than nonsmokers. Thirty-three percent of the workers complained of dyspnea when hurrying on level ground or walking up a slight hill. Half of the workers complained of upper respiratory tract symptoms and eye irritation. Both smokers and exsmokers had significant declines of forced expiratory volume in 1 sec (FEV1.0) with age; exsmokers also had declines with work-years when compared to a nonsmoking comparison population. Nonsmokers with personal dust measurements had a significant decline of FEV1.0 related to respirable dust exposure. A shift study of 104 workers revealed a significant fall in FEV1.0 among nonsmokers and surface workers. Significance was approached in the high dust exposure group. An increase in the mean percent predicted forced vital capacity and FEV1.0 was shown for the 125 workers who had a 5-yr follow-up of pulmonary function. There was no correlation between the shift study decrements and the longitudinal 5-yr follow-up. Industrial hygiene dust sampling found elevated levels of total dust but lower respirable dust, with no detectable free silica.
mesh_terms: D001639:Bicarbonates / Q000009:adverse effects*; D002254:Carbonates / Q000009:adverse effects*; D002908:Chronic Disease; D003371:Cough / Q000139:chemically induced*; D009783:Dermatitis, Occupational / Q000139:chemically induced; D004391:Dust / Q000009:adverse effects; D004417:Dyspnea / Q000139:chemically induced; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000503:physiopathology; D009784:Occupational Diseases / Q000139:chemically induced*; D012123:Pulmonary Ventilation / Q000187:drug effects; D012907:Smoking; D014797:Vital Capacity / Q000187:drug effects
chemical_list: D001639:Bicarbonates; D002254:Carbonates; D004391:Dust; C029065:Magadi soda