title: Canine GM2-gangliosidosis: chemical and enzymatic features.
abstract: The chemical and enzymatic features in tissues of GM2-gangliosidosis are characterized by the analysis of glycolipids and FD-MS, and also by enzymatic analysis with DEAE-Sepharose column chromatography. The results suggest that canine GM2-gangliosidosis is equivalent to human juvenile GM2-gangliosidosis.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D002855:Chromatography, Thin Layer; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs; D005678:G(M2) Ganglioside / Q000378:metabolism*; D005732:Gangliosides / Q000032:analysis* / Q000378:metabolism*; D005733:Gangliosidoses / Q000378:metabolism / Q000662:veterinary*; D006596:Hexosaminidases / Q000302:isolation & purification; D006801:Humans; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000032:analysis*; D013058:Mass Spectrometry; D012794:Sialic Acids / Q000032:analysis; D001619:beta-N-Acetylhexosaminidases
chemical_list: D005732:Gangliosides; D012794:Sialic Acids; D005678:G(M2) Ganglioside; D006596:Hexosaminidases; D001619:beta-N-Acetylhexosaminidases