title: Relationship of the variability of the heterochromatic regions of chromosomes 1, 9, 16, and Y to some anthropometric characteristics in children with embryopathies of unknown etiology and in children with Down syndrome.
abstract: The relationship between variability of the heterochromatic regions of chromosomes 1, 9, 16, and Y, and anthropometric characteristics (length and mass of body, shoulder diameter) in 70 children with embryopathies of unknown etiology and in 40 children with Down syndrome was studied. The positive statistically significant correlations of the C segment lengths of chromosomes 1, 9, 16, their sum included, and the above characteristics were found. The correlation coefficients of Y chromosome were not significant. The questions of the functional role of the structural heterochromatin and its influence on the viability and physical development of the organism are discussed.
mesh_terms: D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D002906:Chromosomes, Human, 6-12 and X; D000013:Congenital Abnormalities / Q000235:genetics*; D004314:Down Syndrome / Q000235:genetics; D005260:Female; D005786:Gene Expression Regulation; D006570:Heterochromatin / Q000502:physiology*; D006801:Humans; D008297:Male; D010641:Phenotype; D014998:Y Chromosome
chemical_list: D006570:Heterochromatin