Frusemide: a safe diuretic during lithium therapy?
This paper reports the effect of frusemide given in therapeutic doses for hypertension in patients receiving prophylactic lithium for affective disorders. It was found that frusemide had no significant effect on plasma lithium concentration in these patients who were studied over a 12-week period. It was concluded that frusemide is a safe diuretic to administer to patients receiving lithium therapy.
D000368:Aged; D001714:Bipolar Disorder / Q000097:blood / Q000188:drug therapy*; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D005260:Female; D005665:Furosemide / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D008094:Lithium / Q000097:blood / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged
D016651:Lithium Carbonate; D005665:Furosemide; D008094:Lithium