[Influence of light on membrane potential of Neurospora crassa cells].
In experiments with left atrial and right ventricular tissues fast sodium current (INa) was decreased by substituting sucrose for sodium in Tyrode's solution and with antiarrhythmic drugs--INa blockers (lidocaine, diphenylhydantoine and ethmozine). It was shown that INa decrease results in the growth of refractoriness (R) of the cardiac tissues. The hypothesis is advanced that the R growth caused by INa decrease is one of the mechanisms of selective sensitiveness of ischemic heart tissues to antiarrhythmic drugs--INa blockers.
D002462:Cell Membrane / Q000502:physiology; D008027:Light; D008564:Membrane Potentials; D008722:Methods; D009491:Neurospora / Q000502:physiology*; D009492:Neurospora crassa / Q000502:physiology*
Vliianie sveta na membrannyĭ potentsial kletok Neurospora crassa.