title: [Population genetic analysis of myopathies among the aborigenes of Pamir].
abstract: Epidemiological studies in the mountainous Pamirs made it possible to specify the prevalence and clinical polymorphism of myopathies. Such factors as a high rate of inbreeding, low migration of the population, the presence in the families of an average 7-8 children contributed to the widespread prevalence of the pathological gene and point to the ancestor's effect. The stable nature of various forms of myopathies in the aborigens is maintained by the accumulation of the gene attributable to a large number of heterozygotic carriers.
mesh_terms: D003241:Consanguinity; D005006:Ethnicity; D005260:Female; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D008297:Male; D009468:Neuromuscular Diseases / Q000453:epidemiology* / Q000235:genetics; D010375:Pedigree; D011110:Polymorphism, Genetic; D013577:Syndrome; D013620:Tajikistan
vernacular_title: Populiatsionno-geneticheskiĭ analiz miopatiĭ u aborigenov Pamira.