[Release and metabolism of brain noradrenaline during experimental ischemia. Effect of glycerol treatment].
The release and catabolism of brain NA were studied after labelling of endogenous NA stores with 3H NA in rats submitted to cerebral ischemia by injecting calibrated microspheres into the internal carotid artery. Twenty four hours after embolization, both NA release and catabolism were found to be reduced. They were restored after treatment with hyperosmolar solution of glycerol.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002545:Brain Ischemia / Q000188:drug therapy / Q000378:metabolism*; D005990:Glycerol / Q000627:therapeutic use*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D005990:Glycerol; D009638:Norepinephrine
Libération et métabolisme de la noradrénaline cérébrale après réalisation d'une ischémie expérimentale. Influence du traitement par le glycérol.