Haemostasis in diabetics.
Haemostasis was studied in 34 diabetic patients with and without detectable vascular complications (micro- and macroangiopathy). Information on platelet functions was obtained by beta-thromboglobulin determination, and of heparin-thrombin coagulation time, platelet aggregation in vivo, and on the condition of the vessel walls by estimation of factor VIII-protein (VIIIR:Ag). The results were suggestive of an increased platelet activity, the most marked abnormalities having been found in cases of angiopathy. Attention is drawn to the therapeutic possibilities offered by studies of the pathogenetic role of the abnormalities of haemostasis in diabetes.
D000328:Adult; D001792:Blood Platelets / Q000502:physiology*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000503:physiopathology*; D005169:Factor VIII / Q000032:analysis; D006487:Hemostasis; D006801:Humans; D008875:Middle Aged; D010974:Platelet Aggregation; D010978:Platelet Factor 4 / Q000032:analysis; D011863:Radioimmunoassay; D001620:beta-Thromboglobulin / Q000032:analysis
D001620:beta-Thromboglobulin; D010978:Platelet Factor 4; D005169:Factor VIII