Studies on the in vitro antigenicity test of the hepatitis B surface antigen preparation and its relationship to the in vivo potency estimate.
The in vitro method for measuring the antigenicity of the Hepatitis B surface (HBs) antigen devised by our laboratories was applied to the antigenicity estimation of intermediate and final products processes of production of hepatitis B (HB) vaccine. The results showed that the method can widely be used at least for the in process control test of HB vaccine.
D005557:Formaldehyde / Q000494:pharmacology; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D017325:Hepatitis B Vaccines; D006358:Hot Temperature; D006801:Humans; D014765:Viral Vaccines / Q000276:immunology*
D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D014765:Viral Vaccines; D005557:Formaldehyde