title: Estimates of left-ventricular volumes by equilibrium radionuclide angiography: importance of attenuation correction.
abstract: To compare the accuracy of attenuated and attenuation-corrected equilibrium radionuclide angiographic (RNA) left ventricular (LV) volume estimates, we studied 23 consecutive patients with biplane contrast cineangiography (CINE). Attenuated RNA end-diastolic (ED) and end-systolic (ES) volumes were calculated from background-corrected ED and ES counts obtained from hand-drawn regions of interest that were normalized to cardiac cycles processed, frame rate, and blood activity. A simple, geometric attenuation correction was performed to obtain attenuation-corrected RNA LV volumes. The attenuated and attenuation-corrected RNA LV EDV estimates correlated with the CINE LV EDVs ; however, the attenuation-corrected RNA LV EDV estimates correlated more closely. Also, the average attenuation-corrected RNA LV EDV did not differ significantly from the mean CINE LV EDV. Attenuated and attenuation-corrected RNA LV ESV estimates also correlated with the CINE LV ESVs , but the attenuation-corrected RNA LV ESV estimates correlated more closely. Also, the average attenuation-corrected RNA LV ESV did not differ significantly from the mean biplane CINE LV ESV.
mesh_terms: D000328:Adult; D000368:Aged; D002306:Cardiac Volume; D002932:Cineangiography / Q000379:methods; D003971:Diastole; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013599:Systole; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium