[Shunt nephritis (author's transl)].
Five patients aged 1.1 - 4.3 years, affected by nephritis secondary to infection of ventriculo-atrial shunt are presented. The time lag between the occurrence of shunt infection and diagnosis of nephropathy varied from 1 to 12 months. In four patients "Staphylococcus epidermidis" was isolated from blood and CSF cultures, and "Staphylococcus aureus" in another one. Renal lesion presented as hematuria and proteinuria, and two patients developed a nephrotic syndrome. Hypertension was present in three patients. C'2 and D'4 hypocomplementemia was a constant feature in the acute stage of the disease. Endocapillary glomerulonephritis was observed in three patients and endo-extracapillary glomerulonephritis in one (70% of crescent formations). After shunt removal and antibiotic administration a favorable clinical course was followed in three patients, with remission of nephropathy signs. The fifth patient (non biopsied) died in the course of a septic process, having kept until then a good renal function.
D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D002675:Child, Preschool; D005260:Female; D006325:Heart Atria; D006801:Humans; D007105:Immune Complex Diseases / Q000209:etiology; D007223:Infant; D008297:Male; D009393:Nephritis / Q000209:etiology*; D018805:Sepsis / Q000209:etiology; D013203:Staphylococcal Infections / Q000150:complications* / Q000276:immunology; D013530:Surgical Wound Infection / Q000150:complications* / Q000276:immunology
Nefritis de "shunt".