Balloon catheter dilatation of stenotic renal artery anastomoses. Experiments in the pig.
Stenotic renal artery anastomoses were produced in pigs in order to investigate the effects of transluminal angioplasty. Six weeks after surgery unilateral dilatation with a modern balloon catheter was performed in 8 pigs. These animals were reexamined with angiography and pressure gradient recording 8 to 10 weeks after dilatation and with post-mortem angiography 8 to 10 weeks later. Only 2 arteries had minimal residual stenoses, while in 6 arteries the stenoses were completely eliminated. Microscopic examination showed thinning of the fibrotic vessel wall, with defects in the internal elastic lamina.
D000800:Angioplasty, Balloon; D000818:Animals; D001794:Blood Pressure; D004195:Disease Models, Animal; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging*; D013552:Swine