Resistance trends of Neisseria gonorrhoeae in the Republic of Korea.
Penicillinase-producing Neisseria gonorrhoeae has increased in the Far East to the point that penicillin can no longer be recommended as the drug of choice, mandating a change to spectinomycin. As part of an ongoing surveillance of antibiotic susceptibilities, minimal inhibitory concentrations of penicillin, tetracycline, spectinomycin, trimethoprim-sulfamethoxazole, cefoxitin, ceftriaxone, cefotaxime, and moxalactam were determined. A disturbing, steady increase in resistance to spectinomycin was documented.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D007723:Korea; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010957:Plasmids; D000198:Spectinomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000198:Spectinomycin