[Survival of Gd- allele carriers in the absence of malaria].
Viability of children in families in which one or both parents had glucose-6-phosphate dehydrogenase deficiency was studied. 159 couples from three districts of the Shekin region of the Azerbaijan SSR were examined. The data were obtained by the half-quality method of fluorescent spots. Four types of marriages were defined using the results of the screening programme. The number of pregnancies and their outcome were analyzed. Elimination of pregnancies in marriages where one or both parents were carriers for Gd- allele, was reliably increased in the antenatal period. This was established under conditions of the absence of selection for hetero- and hemizygotes for this allele in the districts examined. The highest value of elimination of pregnancies was noted in marriages in which both parents were Gd- allele carriers.
D000328:Adult; D000483:Alleles; D001382:Azerbaijan; D005260:Female; D005313:Fetal Death / Q000453:epidemiology / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics* / Q000401:mortality; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D008288:Malaria / Q000235:genetics*; D008297:Male; D011247:Pregnancy
Vyzhivaemost' nositeleĭ allelia Gd- v usloviiakh otsutstvii maliarii.