title: A simple radioaerosol generator and delivery system for pulmonary ventilation studies.
abstract: Details of a simple radioaerosol generator and delivery system are presented. Aerosol streams of 99mTc-DTPA solution of different distributions were produced. The most useful distribution had an activity median aerodynamic diameter (AMAD) of 0.9 micron with a geometric standard deviation of 1.5. This distribution also had more than 96% of aerosol particles with aerodynamic diameter less than 2 micron. The system has been used for patient lung ventilation studies. The aerosol breathing-in period to achieve a satisfactory count rate was 1.8 +/- 0.38 min. The radioaerosol images were excellent and comparable to those obtained with 81mKr gas.
mesh_terms: D000336:Aerosols; D006801:Humans; D007726:Krypton; D008168:Lung / Q000000981:diagnostic imaging*; D004369:Pentetic Acid; D011868:Radioisotopes; D011876:Radionuclide Generators / Q000295:instrumentation*; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate; D014692:Ventilation-Perfusion Ratio
chemical_list: D000336:Aerosols; D011868:Radioisotopes; D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D007726:Krypton; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate