[Morphology of the submandibular lymph nodes of white rats adapting to alpine conditions].
A field experiment has been performed in white noninbred rats in order to study morphometrically structural reconstructions and cellular composition characteristics in the submandibular lymph nodes on the 1st, 3d, 7th, 14th, 21st, 30th and 50th days after lifting them to the altitude of 3,375 m above sea-level. The data obtained demonstrate a stable increase in small lymphocytes contents during the days of the observations; they are accompanied with an increasing specific area of the folliculi and a decreasing area of the cortical plateau. An essential decrease in the plasmic cells and dividing cells contents noted during the whole experiment is regarded to demonstrate an inhibition of the organism's immune reactivity at hypoxic hypoxia. Certain time periods are revealed which are accompanied, during the adaptation period to the high-mountain conditions, with general reactions of definite cell types and the lymph node structures: the 1st-7th days; the 14th-30th days; the 45th day and more. According to the character of the cell reactions in the experiment performed, it is possible to arrange the main structures of the submandibular lymph nodes in the following order: folliculi, cortical plateau, sinuses, medullary cords.
D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D008198:Lymph Nodes / Q000166:cytology*; D051381:Rats; D013363:Submandibular Gland / Q000166:cytology*; D013620:Tajikistan; D013997:Time Factors
Morfologiia podnizhnecheliustnykh limfaticheskikh uzlov belykh krys, adaptiruiushchikhsia k usloviiam vysokogor'ia.