title: Monocyte chemotactic factor production in mixed cultures of maternal and neonatal human lymphocytes.
abstract: The immunological interaction between related maternal and neonatal human lymphocytes was investigated by assaying monocyte chemotactic factor production in mixed cell culture. Lymphokine was detected in a significantly lower proportion of maternal-neonatal cell cultures compared to mixed cultures of cells from unrelated adults and/or neonates. It is possible that a reduced inflammatory mediator production at the feto-maternal interface may contribute to the survival of the fetal allograft.
mesh_terms: D000328:Adult; D002630:Chemotactic Factors / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D066298:In Vitro Techniques; D007231:Infant, Newborn; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology*; D008222:Lymphokines / Q000096:biosynthesis; D008431:Maternal-Fetal Exchange; D009000:Monocytes / Q000276:immunology*; D011247:Pregnancy
chemical_list: D002630:Chemotactic Factors; D008222:Lymphokines