Brain density patterns in schizophrenia and mania.
Regional brain density as measured by X-ray computed tomography was assessed in young schizophrenic (mean age 29.8 years) and manic (mean age 32.7 years) males in order to determine whether this parameter would distinguish between these groups of patients. Our findings reveal similar patterns of interhemispheric density differences in the two groups but significantly greater overall density among manics for the uppermost brain sections studied (16-24 mm above the slice intercepting the body of the lateral ventricles). Clinical implications of these findings are discussed.
D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis*; D001921:Brain / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed