title: Effects of tertiary amine local anesthetics on von Willebrand factor-dependent platelet function: alteration of membrane reactivity and degradation of GPIb by a calcium-dependent protease(s).
mesh_terms: D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D001241:Aspirin / Q000494:pharmacology; D001779:Blood Coagulation Factors / Q000502:physiology*; D002417:Cattle; D002462:Cell Membrane / Q000187:drug effects; D003864:Depression, Chemical; D003992:Dibucaine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D011464:Epoprostenol / Q000494:pharmacology; D006023:Glycoproteins / Q000378:metabolism*; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology; D008565:Membrane Proteins / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D010980:Platelet Membrane Glycoproteins; D013748:Tetracaine / Q000494:pharmacology; D014841:von Willebrand Factor / Q000502:physiology*
chemical_list: D000779:Anesthetics, Local; D001779:Blood Coagulation Factors; D006023:Glycoproteins; D008565:Membrane Proteins; D010980:Platelet Membrane Glycoproteins; D014841:von Willebrand Factor; D013748:Tetracaine; D008012:Lidocaine; D011464:Epoprostenol; D010447:Peptide Hydrolases; D003992:Dibucaine; D001241:Aspirin