Evaluation of visual acuity during laser photoradiation therapy of cancer.
Visual function for ten patients undergoing HPD-PRT was tested using 1) the Graham Field Eye Chart for distance vision, 2) pseudo-isochromatic plates for color vision, and 3) Amsler grid for changes in macular function. Whereas some increases and decreases in ocular function were observed, no clear patterns or changes of significance were observed.
D000328:Adult; D000368:Aged; D003118:Color Perception / Q000187:drug effects; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins / Q000627:therapeutic use / Q000633:toxicity*; D006801:Humans; D053685:Laser Therapy; D007834:Lasers / Q000009:adverse effects*; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D010778:Photochemotherapy / Q000009:adverse effects*; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use / Q000633:toxicity*; D014792:Visual Acuity / Q000187:drug effects*
D006415:Hematoporphyrins; D011838:Radiation-Sensitizing Agents; D017324:Hematoporphyrin Derivative