[Adhesion prophylaxis - a comparative experimental animal study].
A number of 45 female rabbits were anesthetized, and intra-abdominal lesions were set at either of the uterine horns and the abdominal wall in a standardized technique. Before closure of the abdomen the collective--divided into three subgroups of 15 animals each--received i.p. one of the following pharmaca: Group I: solution of physiologic saline (control group) Group II: poly-1-vinyl-2-pyrollidon iodine complex Group III: streptokinase/streptodornase. Two weeks after the first operation a second laparotomy was performed, and the sites were inspected. The adhesions were examined and their quantity and quality documented. Statistical evaluation showed that groups I and II were significantly different from group III as to the extent and intensity of the adhesions.
D000009:Abdominal Muscles; D000818:Animals; D005260:Female; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000627:therapeutic use*; D011817:Rabbits; D013223:Statistics as Topic; D013299:Streptodornase and Streptokinase / Q000627:therapeutic use*; D000267:Tissue Adhesions / Q000517:prevention & control*; D014591:Uterine Diseases / Q000517:prevention & control
D011206:Povidone-Iodine; D013299:Streptodornase and Streptokinase; D011205:Povidone
Adhäsionsprophylaxe - Eine vergleichende tierexperimentelle Studie.