Irrigation with mercury chloride and sodium hypochlorite to prevent local recurrence after excision of conjunctival melanoma. An experimental study.
Two chemical agents, sodium hypochlorite 0.5% (Dakin's solution) and mercury chloride 0.1%, capable of killing seeded tumour cells, were used for washing the cornea and conjunctiva of rabbits. Both agents produced considerable superficial lesions in the cornea and conjunctiva after irrigation for 3 and 5 min, but these were restored to normal after 2 weeks.
D000818:Animals; D003230:Conjunctival Neoplasms / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery; D008627:Mercuric Chloride; D008628:Mercury / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D011817:Rabbits; D012973:Sodium Hypochlorite / Q000627:therapeutic use*
D008627:Mercuric Chloride; D012973:Sodium Hypochlorite; D008628:Mercury