title: The "concrete" histological diagnosis of cerebral tumours of neuroectodermic origin.
abstract: The "concrete" histological criteria for establishing the benignity or malignancy of cerebral tumours of neuroectodermic origin (gliomas and medulloblastomas, respectively granulocytomas) may be thus synthetized: 1) the benign tumours have a fibrocellular structure, the neoplastic cells being relatively monomorphous; vascular hyperplasia is absent, as well as necrotic and hemorrhagic foci; 2) the malignant tumours are hyper- and polymorphocellular, the fibrillar component being reduced or absent; vascular hyperplasia as well as the presence of necrotic and/or hemorrhagic foci is a constant characteristic; the tumoral cells often infiltrate the perivascular spaces.
mesh_terms: D001254:Astrocytoma / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D004806:Ependymoma / Q000473:pathology*; D006652:Histological Techniques; D006801:Humans; D008527:Medulloblastoma / Q000473:pathology*; D009837:Oligodendroglioma / Q000473:pathology*