[Comparison of the effects of almitrine, raubasine and 5023 SE on arterial oxygen desaturation during exercise].
The effects of almitrine (60 mg/24 h), raubasine (20 mg/24 h) and Duxil administered orally were compared in 30 elderly subjects (mean age: 60 years) who showed a decrease in oxygen saturation during maximum exercise. After 1 month of treatment, raubasine proved ineffective whereas almitrine and Duxil significantly reduced this decrease. The effect of Duxil was significantly more pronounced than that of almitrine.
D015765:Almitrine; D001158:Arteries; D004338:Drug Combinations / Q000494:pharmacology; D006801:Humans; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D005082:Physical Exertion; D010879:Piperazines / Q000494:pharmacology*; D046948:Secologanin Tryptamine Alkaloids; D015016:Yohimbine / Q000494:pharmacology*
D004338:Drug Combinations; D010879:Piperazines; D046948:Secologanin Tryptamine Alkaloids; D015016:Yohimbine; C005709:raubasine; C037558:almitrine, raubasine drug combination; D015765:Almitrine; D010100:Oxygen
Comparaison des effets de l'almitrine, de la raubasine et du 5023 SE sur la désaturation artérielle en oxygène lors de l'exercice.