[Lymphocyte stimulation in the primed lymphocyte typing test by as yet unknown HLA-linked antigens (WP-alleles)].
Lymphocytes from HLA-identical unrelated donors often show positive stimulation in the mixed lymphocyte culture, possibly caused by alleles of HLA-linked, but not yet defined gene loci. In order to investigate such determinants lymphocytes from HLA-DR identical individuals were primed and tested in the PLT system. Family and population data indicate that such antigens exist and can be detected in vitro.
D000483:Alleles; D005260:Female; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000145:classification; D008297:Male
D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II
Lymphozytenstimulation im PLT-Test durch bisher unbekannte HLA-gekoppelte Antigene (WP-Allele).