title: Immune complex glomerulonephritis in hydralazine-induced SLE.
abstract: Renal disease, a major feature of systemic lupus erythematosus (SLE), rarely occurs in drug-induced SLE. Immune complex glomerulonephritis has been demonstrated in a few cases of SLE following procainamide or anticonvulsant therapy but has not been documented in association with hydralazine-induced SLE despite the recognition of this syndrome 30 years ago. We report the clinical and renal pathologic findings in a patient with hydralazine-induced lupus nephritis and review the renal pathologic material in earlier reports of hydralazine-induced SLE.
mesh_terms: D000368:Aged; D001167:Arteritis / Q000150:complications / Q000473:pathology; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects*; D007105:Immune Complex Diseases / Q000150:complications* / Q000473:pathology; D007674:Kidney Diseases / Q000209:etiology; D007678:Kidney Glomerulus / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D009336:Necrosis; D012077:Renal Artery / Q000473:pathology
chemical_list: D006830:Hydralazine