title: The core protein of fibroblast proteoheparan sulphate consists of disulphide-bonded subunits.
abstract: Fibroblast proteoheparan sulphate has a disulphide-bonded subunit structure. The core protein appears to consist of two polypeptides each of Mr 80 000-100 000. As shown elsewhere [Carlstedt, Cöster, Malmström & Fransson (1983) J. Biol. Chem. in the press], both polypeptide molecules carry four to six heparan sulphate side chains (approx. Mr 20 000) and an unknown number of oligosaccharide units, giving the whole macromolecule an Mr in the range 300 000-400 000.
mesh_terms: D011508:Chondroitin Sulfate Proteoglycans; D002850:Chromatography, Gel; D004220:Disulfides / Q000032:analysis; D005347:Fibroblasts / Q000032:analysis*; D006025:Glycosaminoglycans; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate; D006801:Humans; D011506:Proteins; D011509:Proteoglycans
chemical_list: D011508:Chondroitin Sulfate Proteoglycans; D004220:Disulfides; D006025:Glycosaminoglycans; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate; D011506:Proteins; D011509:Proteoglycans