title: Sequential utilization of mixed monosaccharides by yeasts.
abstract: Four yeasts (Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida utilus, and Rhodotorula toruloides) were tested for their ability to grow and consume D-glucose, D-xylose, D-xylulose, and D-xylitol. Sequential utilization of substrates was observed when D-glucose as mixed with D-xylulose as the carbon source. Catabolite inhibition was tentatively concluded to be responsible for this regulatory mechanism. D-Glucose was also found to inhibit the utilization of D-xylose and D-xylitol in C. utilus and R. toruloides. D-Xylose, D-xylitol, and D-xylulose were consumed simultaneously by R. toruloides and C. utilus.
mesh_terms: D001203:Ascomycota / Q000378:metabolism*; D001692:Biological Transport; D002175:Candida / Q000378:metabolism*; D005690:Galactose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D007700:Kinetics; D003904:Mitosporic Fungi / Q000378:metabolism*; D009005:Monosaccharides / Q000378:metabolism*; D012248:Rhodotorula / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D012568:Schizosaccharomyces / Q000378:metabolism*; D013045:Species Specificity; D014993:Xylitol / Q000378:metabolism; D014994:Xylose / Q000378:metabolism; D014996:Xylulose / Q000378:metabolism
chemical_list: D009005:Monosaccharides; D014996:Xylulose; D014994:Xylose; D005947:Glucose; D014993:Xylitol; D005690:Galactose