title: Effectiveness of cefoperazone in treating cutaneous infections.
abstract: Twenty-eight patients with severe cutaneous infections received cefoperazone, 2 grams intramuscularly twice a day for seven days. A wide range of gram-positive and gram-negative pathogens were isolated from admission cultures. All patients showed rapid clinical improvement. Two patients did not complete the full course of therapy because of intervening medical problems unrelated to the antibiotic. No significant side effects were noted. Relapses or reinfections occurred in two patients. In conclusions, cefoperazone is a safe and effective antibiotic for use in skin infections requiring parenteral therapy.
mesh_terms: D000427:Alcohol Deterrents / Q000008:administration & dosage / Q000627:therapeutic use*; D002438:Cefoperazone; D002481:Cellulitis / Q000188:drug therapy; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D005533:Foot Dermatoses / Q000188:drug therapy; D006801:Humans; D007273:Injections, Intramuscular; D011549:Pseudomonas / Q000187:drug effects; D012874:Skin Diseases, Infectious / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013290:Streptococcal Infections / Q000188:drug therapy
chemical_list: D000427:Alcohol Deterrents; D002511:Cephalosporins; D002438:Cefoperazone