[Effect of methylmercury chloride on mitosis in human lymphocytes in culture: ultrastructural study].
The ultrastructural study of proliferating human lymphocytes poisoned by methylmercury chloride, shows that this product disorganizes and alters the different constituents of the mitotic figure. The chromosomes, partially decondensed, are covered with protuberances and connected by various chromatin bridges. Tubular structures are changed. In disorganized cellular centers, the badly bounded centrioles are often thickened. Membraneous systems are altered.
D002478:Cells, Cultured; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D008767:Methylmercury Compounds / Q000494:pharmacology*; D008854:Microscopy, Electron; D008938:Mitosis / Q000187:drug effects*
D008767:Methylmercury Compounds; C004925:methylmercuric chloride
Action du chlorure de méthylmercure sur la mitose de lymphocytes humains en culture : étude ultrastructurale.