Topical benzoyl peroxide increases the sebum excretion rate in patients with acne.
Investigations on fifteen patients with acne showed that at the end of 1 and 2 months of treatment 5% benzoyl peroxide increased the sebum excretion rate by 22.5%. This rise in sebum excretion is probably due to the comedolytic activity of benzoyl peroxide which will influence the pooling of sebum in the upper reaches of the pilosebaceous duct.
D000152:Acne Vulgaris / Q000188:drug therapy / Q000378:metabolism*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D001585:Benzoyl Peroxide / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D010545:Peroxides / Q000008:administration & dosage*; D012629:Sebum / Q000187:drug effects / Q000378:metabolism*
D010545:Peroxides; D001585:Benzoyl Peroxide