title: Effect on memory processes of anti-vasopressin serum microinjected into the dorsal raphe nucleus: the role of catecholaminergic neurotransmission.
abstract: Anti-arginine8-vasopressin serum was microinjected into the mesencephalic dorsal raphe nucleus immediately after the learning trial, in a one-trial learning passive avoidance reaction. The treatment attenuated passive avoidance behavior 24 h after treatment, suggesting a role of the endogenous vasopressin of this area in memory processes. On the other hand, the antiserum did not influence passive avoidance behavior if 6-hydroxydopamine was microinjected into the raphe region. The data suggest that the antiserum may have primarily interacted with catecholaminergic terminals, which enter the dorsal raphe nucleus.
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000276:immunology; D001362:Avoidance Learning / Q000502:physiology; D001933:Brain Stem / Q000502:physiology*; D002395:Catecholamines / Q000502:physiology*; D006892:Hydroxydopamines / Q000008:administration & dosage / Q000494:pharmacology; D007106:Immune Sera / Q000008:administration & dosage / Q000494:pharmacology; D008297:Male; D008568:Memory / Q000502:physiology*; D008845:Microinjections; D011817:Rabbits; D011903:Raphe Nuclei / Q000502:physiology*; D051381:Rats; D011941:Receptors, Adrenergic / Q000502:physiology*; D009435:Synaptic Transmission; D014667:Vasopressins / Q000502:physiology
chemical_list: D002395:Catecholamines; D006892:Hydroxydopamines; D007106:Immune Sera; D011941:Receptors, Adrenergic; D014667:Vasopressins; D001127:Arginine Vasopressin