Hepatocellular adenoma in a young woman with beta-thalassemia and secondary iron overload.
The occurrence of a hepatocellular adenoma is described in a young woman with beta-thalassemia and secondary iron overload. This patient had no history of oral contraceptive use, and in fact was hypogonadal as a result of iron deposition in pituitary and gonadal tissue. Although hepatocellular carcinoma frequently occurs in diseases associated with iron overload, this is the first report of a benign liver tumor associated with secondary iron overload.
D000293:Adolescent; D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000150:complications; D007501:Iron / Q000097:blood*; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D013789:Thalassemia / Q000150:complications*
D007501:Iron