Determination of liver and spleen perfusion by quantitative sequential scintigraphy: results in normal subjects and in patients with portal hypertension.
Quantitative sequential hepatosplenic scintigraphy was performed to determine the arterial and portal components of the total liver circulation in 135 patients (no liver disease in 20, liver cirrhosis and portal ;hypertension in 115). Portal circulation in healthy patients is calculated to be 70.4 +/- 6.2% of the total liver blood flow, whereas patients with portal hypertension showed a clear reduction of portal perfusion to 20.2 +/- 10.9%. Thirteen of 20 patients having portosystemic shunt surgery showed no portal perfusion. This new, noninvasive diagnostic technique yields vital information particularly useful in ;the surgical evaluation of portal hypertension. Other indications are also discussed.
D000792:Angiography; D006801:Humans; D006975:Hypertension, Portal / Q000000981:diagnostic imaging* / Q000473:pathology; D008099:Liver / Q000098:blood supply / Q000000981:diagnostic imaging*; D010477:Perfusion; D011168:Portal System / Q000000981:diagnostic imaging; D011170:Portasystemic Shunt, Surgical; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013670:Sodium Pertechnetate Tc 99m; D013154:Spleen / Q000000981:diagnostic imaging*; D013667:Technetium
D013667:Technetium; D013670:Sodium Pertechnetate Tc 99m