High-fiber diet in the control of diabetes in rats.
The effects of high-fiber diet on the metabolic states in streptozotocin-induced diabetic rats were investigated. The animals were divided into three groups: group A fed on a diet containing 5% of fiber (bagasse), group B paired-fed on a control diet and group C fed on a control diet ad libitum. The body weight gain was greater and the fasting blood sugar level was lower in A than B and C. The plasma triglyceride level was lowest in A, while no significant difference in the serum total cholesterol level was observed between A and B. Plasma glucagon levels were decreased in A and increased significantly in B and C. Plasma insulin levels were not changed in these groups. These results support the theory that a high-fiber diet is an effective therapeutic regimen for the control of metabolic derangement in diabetics.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002482:Cellulose / Q000627:therapeutic use*; D002784:Cholesterol / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000178:diet therapy*; D004043:Dietary Fiber / Q000627:therapeutic use*; D005934:Glucagon / Q000097:blood; D008297:Male; D051381:Rats; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D004043:Dietary Fiber; D014280:Triglycerides; D002482:Cellulose; D005934:Glucagon; D002784:Cholesterol