Bilateral cystic nephroblastomas and botryoid sarcoma involving vagina and urinary bladder in a child with microcephaly, arhinencephaly, and bilateral cataracts.
The case of a 1-year-old infant with bilateral cystic nephroblastomas, a botryoid sarcoma involving the vagina and urinary bladder, microcephaly, arhinencephaly and bilateral cataracts is reported. The unusual association of these lesions suggests a syndrome due to genetic abnormalities.
D000015:Abnormalities, Multiple / Q000150:complications / Q000473:pathology; D002386:Cataract / Q000150:complications / Q000151:congenital / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008032:Limbic System / Q000002:abnormalities; D008831:Microcephaly / Q000150:complications / Q000473:pathology; D009378:Neoplasms, Multiple Primary; D012208:Rhabdomyosarcoma / Q000150:complications / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000473:pathology; D014625:Vaginal Neoplasms / Q000150:complications / Q000473:pathology; D009396:Wilms Tumor / Q000150:complications / Q000473:pathology