Fulminant lung metastases from cancer of the breast.
Fulminant, rapidly fatal pulmonary metastatic disease occurred in two breast cancer patients. The radiologic appearance in both suggested infection. Immunosuppression may have contributed to this overwhelming illness. Attempts to obtain a tissue diagnosis are warranted in cancer patients if acute pulmonary infiltrates do not respond to appropriate antibiotics.
D000328:Adult; D001943:Breast Neoplasms; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy / Q000556:secondary*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects; D007111:Immunity, Cellular; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000150:complications / Q000556:secondary*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D012131:Respiratory Insufficiency / Q000209:etiology; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D003520:Cyclophosphamide; D005472:Fluorouracil; D011241:Prednisone; D008727:Methotrexate