title: Effect of test meals of varying dietary fiber content on plasma insulin and glucose response.
abstract: To assess the effect of dietary fiber on glucose tolerance four different meals of varying fiber content but identical protein fat and carbohydrate content were fed to eight healthy men aged 22 to 45. Each meal provided 75 g of carbohydrate as liquid glucose formula, as brown rice, pinto beans, or All Bran. The mean plasma glucose and insulin responses were highest following the formula, and least for All Bran and pinto beans. Rice produced nearly as great a rise in insulin and glucose as did the formula. The rank of each meal by content of neutral detergent fiber was nearly the inverse of the rank by magnitude of the insulin response evoked, fiber content being greatest in All Bran (18 g) and pinto beans (16.2 g), low in rice (2.8 g) and absent from the formula. It was concluded that dietary fiber dampened the insulin response to a high carbohydrate meal.
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D002482:Cellulose / Q000494:pharmacology*; D004040:Dietary Carbohydrates / Q000494:pharmacology; D004043:Dietary Fiber / Q000008:administration & dosage / Q000032:analysis / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D007887:Fabaceae / Q000032:analysis; D005526:Food, Formulated / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012275:Oryza / Q000032:analysis; D010946:Plants, Medicinal; D014280:Triglycerides / Q000097:blood; D014908:Triticum / Q000032:analysis
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D007328:Insulin; D014280:Triglycerides; D002482:Cellulose