title: [Adjuvant chemotherapy in treatment of non seminomatous germinal testicular tumor. Results and reflexions about 77 cases (author's transl)].
abstract: To define prognostic factors of testicular cancer and to develop a strategic therapy based on clinical, pathological and biological findings, 77 cases of non seminomatous testis tumor, observed in G.F. Leclerc Center from 1967 to 1977, have been analysed. For all these patients early chemotherapy program was associated with surgery; radiation therapy was reserved for stages with retroperitoneal metastatic disease. Results of this review confirmed the interest of such medical treatment which improved survival in all stages of disease. Some prognostic factors could be detailed from these cases: nature of tumoral components, invading of lymph node, presence or not of biological markers; identification of these would unable us to choose the best adjuvant chemotherapy program and to define its place in the management of testis tumor's treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002822:Choriocarcinoma / Q000188:drug therapy / Q000628:therapy; D004407:Dysgerminoma / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D013724:Teratoma / Q000188:drug therapy / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Chimiothérapie adjuvante dans le traitement des tumeurs germinales du testicule. Résultats et réflexions à partir de 77 observations.