A substance in L-929 cell extracts which replaces the ascorbate requirement for prolyl hydroxylase in a tritium release assay for reducing cofactor; correlation of its concentration with the extent of ascorbate-independent proline hydroxylation and the level of prolyl hydroxylase activity in these cells.
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism / Q000494:pharmacology*; D001842:Bone and Bones / Q000196:embryology / Q000201:enzymology; D002474:Cell-Free System; D002642:Chick Embryo; D006900:Hydroxylation; D007739:L Cells / Q000201:enzymology; D010084:Oxidation-Reduction; D011393:Procollagen-Proline Dioxygenase / Q000378:metabolism*; D011622:Pterins / Q000378:metabolism; D013010:Sonication
D011622:Pterins; D011393:Procollagen-Proline Dioxygenase; D001205:Ascorbic Acid