Methionine enkephalin inhibits the bursting activity of the Br-type neuron in Helix pomatia L.
The present study demonstrates that methionine enkephalin can inhibit the normal bursting activity pattern of the RPal or Br-type neuron and this inhibition can be blocked by prior treatment with naloxone, the selective opiate antagonist. The study demonstrates indirectly the presence of opiate-like receptors in Helix pomatia.
D000818:Animals; D004594:Electrophysiology; D004723:Endorphins / Q000494:pharmacology*; D004744:Enkephalin, Methionine; D004745:Enkephalins / Q000494:pharmacology*; D006372:Helix, Snails / Q000187:drug effects* / Q000502:physiology; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011957:Receptors, Opioid / Q000187:drug effects
D004723:Endorphins; D004745:Enkephalins; D011957:Receptors, Opioid; D009270:Naloxone; D004744:Enkephalin, Methionine