Tricyclic antidepressant drug treatment decreases alpha 2-adrenoreceptors on human platelet membranes.
D000818:Animals; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology* / Q000627:therapeutic use; D001792:Blood Platelets / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D006801:Humans; D007099:Imipramine / Q000494:pharmacology; D066298:In Vitro Techniques; D001523:Mental Disorders / Q000188:drug therapy; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*
D000929:Antidepressive Agents, Tricyclic; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D007099:Imipramine