Antibody to parainfluenza virus types 1, 2 and 3 in sera and nasal secretions of persons of different age.
Serum and secretory antibody levels against 3 types of parainfluenza virus were determined in persons ranging in age from 1 month to 74 years. With a slight decline in the group of 7 months to 2 years of children, the number of positive findings increased with age, reaching maximum in the groups of 16-24 years [types 1 and 2] and 25-74 years [type 3] old persons. Nasal secretory antibodies against parainfluenza type 3 virus were detected in all age categories, the highest number of positive findings occurred in the group of 16-24 years old persons. Secretory antibodies against type 2 virus were detected also in all age groups, but the number of positive findings was considerably lower. Secretory antibodies against type 1 virus were detectable in persons over 5 years of age, with a maximum in the age category of 16-24 years. The percentage of positive persons with antibody to type 1 virus was the lowest.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007223:Infant; D008875:Middle Aged; D009297:Nasal Mucosa / Q000276:immunology*; D010222:Parainfluenza Virus 1, Human / Q000276:immunology*; D010223:Parainfluenza Virus 2, Human / Q000276:immunology*; D010224:Parainfluenza Virus 3, Human / Q000276:immunology*; D018108:Respirovirus / Q000276:immunology*
D000914:Antibodies, Viral