Rat hepatocyte-mediated mutagenesis of human cells by carcinogenic polycyclic aromatic hydrocarbons but not organochlorine pesticides.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology*; D000818:Animals; D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000494:pharmacology*; D001711:Biotransformation; D002478:Cells, Cultured; D006801:Humans; D006843:Hydrocarbons, Chlorinated; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D007306:Insecticides / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism*; D008297:Male; D009152:Mutagenicity Tests; D009154:Mutation / Q000187:drug effects*; D051381:Rats; D012867:Skin / Q000187:drug effects*
D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D001564:Benzo(a)pyrene; D015127:9,10-Dimethyl-1,2-benzanthracene; D007041:Hypoxanthine Phosphoribosyltransferase