Immune response of guinea pigs to varicella vaccine strain (OKA) and wild strains.
An immune response (neutralizing and complement fixing antibodies) was detected in guinea pigs to varicella vaccine strain (Oka), but not to 2 wild strains. The possible use of guinea pigs and the vaccine strain (Oka) as a model system is discussed.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D003168:Complement Fixation Tests; D006168:Guinea Pigs; D014645:Herpesvirus 3, Human / Q000276:immunology* / Q000472:pathogenicity; D008297:Male; D009500:Neutralization Tests; D013045:Species Specificity
D000914:Antibodies, Viral