Amino acid sequence of p15 from avian myeloblastosis virus complex.
The complete amino acid sequence of the p15 gag protein from avian myeloblastosis virus (AMV) complex has been determined by sequential Edman degradation of the intact molecule and of peptide fragments generated by limited tryptic cleavage, cleavage with staphylococcal protease, and cyanogen bromide cleavage. AMV p15 is a single-chain protein containing 124 amino acids. The charged amino acids tend to be clustered in the primary structure. p15 contains a single cysteine at position 113 which may be essential for the p15 associated proteolytic activity. However, p15 shows no appreciable sequence homology with papain or other classical thiol proteases.
D000595:Amino Acid Sequence; D000956:Antigens, Viral / Q000032:analysis*; D001354:Avian Leukosis Virus / Q000032:analysis*; D009189:Avian Myeloblastosis Virus / Q000032:analysis*; D015683:Gene Products, gag; D014764:Viral Proteins / Q000032:analysis*
D000956:Antigens, Viral; D015683:Gene Products, gag; D014764:Viral Proteins