[Surface phenotype and suppressor function of the blood lymphocytes in multiple myeloma].
Surface phenotype of peripheral blood lymphocytes was studied in 18 patients with myeloma by combined rosette-forming and immunofluorescent methods. A high content of B lymphocytes with the identical type of immunoglobulin, and a decreased level of T lymphocytes were revealed. The increased activity of spontaneous and Con A-induced suppressor activity and cytochemical changes of some intracellular hydrolytic enzymes were found in lymphocytes of patients with myeloma.
D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D008875:Middle Aged; D009101:Multiple Myeloma / Q000276:immunology*; D010641:Phenotype; D011971:Receptors, Immunologic / Q000276:immunology; D012397:Rosette Formation; D013499:Surface Properties; D013601:T-Lymphocytes / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D011971:Receptors, Immunologic
Poverkhnostnyĭ fenotip i supressornaia funktsiia limfotsitov krovi pri mielomnoĭ bolezni.