Mechanisms of pathogenicity of anaerobic bacteria of clinical interest.
The host factors leading to anaerobic infection and the various models of anaerobic infection, namely direct effect of a single toxin, multiple toxin-aggressin-systems, enterotoxic mechanisms, endogenous infections with non-clostridial anaerobes, and synergistic infections, are reviewed. Production of carcinogens and co-carcinogens by anaerobes is also discusssed.
D000693:Anaerobiosis; D001419:Bacteria / Q000472:pathogenicity*; D001424:Bacterial Infections / Q000209:etiology*; D001427:Bacterial Toxins / Q000633:toxicity; D002273:Carcinogens / Q000378:metabolism; D003016:Clostridium perfringens / Q000472:pathogenicity; D004768:Enterotoxins / Q000633:toxicity; D005517:Foodborne Diseases / Q000209:etiology; D005738:Gas Gangrene / Q000209:etiology; D006801:Humans; D007109:Immunity
D001427:Bacterial Toxins; D002273:Carcinogens; D004768:Enterotoxins