Lung parenchyma response of rats stimulated with living pneumococci by respiratory way. A histologic, histochemical and electron microscopic study.
The pulmonary intralobular connective tissue of albino rats stimulated by a pulverized suspension of living pneumococci is the site of an abundant cell proliferation and pyronine-plasma cell reaction, having as molecular substratum enhanced activity of Alk-Ph-ase, ATP-ase, SDH-ase and LDH-ase. Cells in varying degree of plasmacytic differentiation were evidenced electron microscopically at alveolar wall level.
D000818:Animals; D002455:Cell Division; D005260:Female; D007114:Immunization; D008168:Lung / Q000201:enzymology / Q000276:immunology*; D008297:Male; D010088:Oxidoreductases / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D010950:Plasma Cells / Q000166:cytology; D011650:Pulmonary Alveoli / Q000166:cytology; D051381:Rats; D013296:Streptococcus pneumoniae / Q000276:immunology*
D010088:Oxidoreductases; D010744:Phosphoric Monoester Hydrolases