title: [Effect of changes in the external concentration of sodium, chlorine, and potassium ions on subsequent depolarization of a single node of Ranvier of isolated nerve fibers].
abstract: Change in external concentration of Na+ (from 0 to 240 mmol), Cl- (from 0 to 120 mmol), and K+ (from 2.5 to 10--30 mmol) had no significant effect on the negative trace potential in the Ranvier isthmus of Rana ridibunda. In K+-free Ringer's solution a trace hyperpolarization occurred. The negative trace potential of the isthmus increased in blockade of the membrane potassium channels with tetraethylammonium chloride or 4-aminopyrydine.
mesh_terms: D000631:Aminopyridines / Q000494:pharmacology; D000818:Animals; D002712:Chlorides / Q000494:pharmacology*; D066298:In Vitro Techniques; D007473:Ion Channels / Q000502:physiology; D011188:Potassium / Q000378:metabolism / Q000494:pharmacology*; D011895:Rana ridibunda; D011901:Ranvier's Nodes / Q000187:drug effects*; D012964:Sodium / Q000494:pharmacology*; D013757:Tetraethylammonium Compounds / Q000494:pharmacology
chemical_list: D000631:Aminopyridines; D002712:Chlorides; D007473:Ion Channels; D013757:Tetraethylammonium Compounds; D012964:Sodium; D011188:Potassium
vernacular_title: Vliianie izmeneniia naruzhnoĭ kontsentratsii ionov natriia, khlora i kaliia na sledovuiu depolarizatsiiu odinochnogo perekhvata Ranv'e izolirovannykh nervnykh volokon.