Effect of acyclovir on recurrence of herpes simplex skin lesions in mice.
Acyclovir (ACV) was effective in preventing recurrence of herpes simplex in mice whose skin was stripped with cellophane tape. Treatment with ACV did not eliminate latent herpes simplex virus from the cervical ganglia.
D000212:Acyclovir; D000818:Animals; D005260:Female; D005728:Ganglia, Sympathetic / Q000382:microbiology; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006561:Herpes Simplex / Q000188:drug therapy* / Q000382:microbiology; D006968:Hypersensitivity, Delayed; D051379:Mice; D012008:Recurrence; D018139:Simplexvirus / Q000302:isolation & purification; D012867:Skin / Q000382:microbiology; D013997:Time Factors
D006147:Guanine; D000212:Acyclovir