title: Diagnostic significance of connective tissue enzymes.
abstract: In spite of the extensive literature, little is known of the diagnostic value of the enzymes of connective tissue metabolism. This review summarizes the available information and assesses the significance of enzyme measurements for the diagnosis of hereditary and nonhereditary connective tissue diseases, with emphasis being given to the roles of abnormal activities of collagenases and lysosomal glycosidases in the detection of fibrotic processes.
mesh_terms: D000118:Acetylglucosaminidase / Q000378:metabolism; D004796:Clinical Enzyme Tests; D003238:Connective Tissue / Q000201:enzymology*; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D006801:Humans; D006867:Hydrolases / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D008247:Lysosomes / Q000201:enzymology; D003012:Microbial Collagenase / Q000378:metabolism*
chemical_list: D007527:Isoenzymes; D006867:Hydrolases; D000118:Acetylglucosaminidase; D003012:Microbial Collagenase