title: [Treatment of frostbites. Analysis of results in twenty patients with buflomedil chlorhydrate (author's transl)].
abstract: Twenty cases of mountain frostbites of various degrees are presented, showing that buflomedil hydrochloride allows an improvement of the usual treatment of frostbites. Two protocols were used: 1) in 8 patients, after the usual treatment (bath at 38 degrees C, dextran perfusion, heparintherapy, antibiotherapy), buflomedil hydrochlorhydrate was administered by perfusion of 8 vials/day, during 10 days; 2) in 12 patients, buflomedil was injected directly by intravenous route on their arrival in the Emergency room. When the injection is given early, a potentiation of the effects of the warm bath is observed, and in two cases, this therapy has perhaps allowed to avoid the amputation.
mesh_terms: D000328:Adult; D002090:Butyrophenones / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005627:Frostbite / Q000188:drug therapy* / Q000628:therapy; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D011759:Pyrrolidines / Q000008:administration & dosage / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D002090:Butyrophenones; D011759:Pyrrolidines; D014665:Vasodilator Agents; C010651:buflomedil
vernacular_title: Le traitement des gelures de montagne. Analyse des résultats obtenus sur vingt gelés par le chlorhydrate de buflomedil.