Mouse hepatitis virus strain 3 infection of C57, A/Sn and A/J strain mice and their macrophages. Brief report.
Mouse hepatitis virus strain 3 replicated in C57, A/Sn and A/J strain mouse macrophages with the production of a clear cytopathic effect, although only C57 and A/Sn strains of mice were killed with similar MHV3 dilutions. We could not confirm a previous report showing that in vitro cultured macrophages from A/J strain mice were resistant to MHV3 infection.
D000818:Animals; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral; D006524:Hepatitis, Viral, Animal / Q000401:mortality; D008264:Macrophages / Q000382:microbiology*; D051379:Mice; D008815:Mice, Inbred Strains; D006517:Murine hepatitis virus / Q000254:growth & development* / Q000472:pathogenicity; D013045:Species Specificity; D014779:Virus Replication