[Research on substances with antiviral activity. XVIII. Bis-amidinohydrazones of N-heterocyclic aromatic dialdehydes].
Some bis-amidinohydrazones of N-heterocyclic aromatic dialdehydes were synthesised and tested in vitro against the MP mutant of the herpes simplex virus type 1 [HSV - I (MP)]. Of the compounds tested, only those with and indole substrate showed some measure of biological activity.
D000998:Antiviral Agents / Q000138:chemical synthesis*; D006835:Hydrazones / Q000138:chemical synthesis* / Q000494:pharmacology; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects
D000998:Antiviral Agents; D006835:Hydrazones; D007211:Indoles
Richerche su sostanze ad attività antivirale. Nota XVIII - bis-amidinoidrazoni di dialdeidi aromatiche N-eterocicliche.