Mechanism underlying the inhibition of platelet aggregation by eicosapentaenoic acid and its metabolites.
D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism; D000242:Cyclic AMP / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004537:Eicosanoic Acids / Q000378:metabolism / Q000494:pharmacology*; D015118:Eicosapentaenoic Acid; D011464:Epoprostenol / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects*; D011457:Prostaglandins D / Q000494:pharmacology; D011458:Prostaglandins E / Q000494:pharmacology; D011817:Rabbits; D013329:Structure-Activity Relationship
D001095:Arachidonic Acids; D004537:Eicosanoic Acids; D005231:Fatty Acids, Unsaturated; D011457:Prostaglandins D; D011458:Prostaglandins E; D015118:Eicosapentaenoic Acid; D011464:Epoprostenol; D000242:Cyclic AMP