title: [The double-pentagastrin test for measuring the gastric secretory capacity in patients of an advanced or great age (author's transl)].
abstract: For studying the changes in the gastric secretory capacity that are caused by old age, the double-pentagastrin test is recommended; this test serves to examine the gastric secretory reaction by administering twice pentagastrin in a dose of 6 micrograms/kg. With this suggested method it was possible to find out the age-dependent decrease in the functional possibilities of the gastric secretory system. It is demonstrated that these possibilities are determined by the physiological changes in the gastric secretory system and by the peculiarities of its neurohumoral regulation. Observations indicate an increasing sensitivity, with advancing years, of the secretory cells with respect to pentagastrin and a faster exhaustibility of the gastric secretory reaction if stimulated by pentagastrin.
mesh_terms: D000328:Adult; D000368:Aged; D005753:Gastric Mucosa / Q000378:metabolism*; D005853:Geriatrics; D006801:Humans; D010418:Pentagastrin; D009435:Synaptic Transmission
chemical_list: D010418:Pentagastrin
vernacular_title: Der Doppel-Pentagastrin-Test zur Untersuchung der sekretorischen Magenfunktion bei Patienten fortgeschrittenen und hohen Alters.