title: Satellite DNA relationships in man and the primates.
abstract: We have investigated the genomes of a series of primates to identify the presence of sequences related to human satellite DNAs I, II and III by restriction enzyme digestion and hybridisation with probes of these satellite DNAs. Where we have found such related sequences we have examined the extent to which they have diverged by measuring the stability of the hybrids. DNA satellite III is the oldest sequence being common to species which have diverged some 24 million years ago. In contrast DNA satellites I and II are of much more recent origin. Our results permit us to draw conclusions about the way these sequences have evolved, and how the evolution of repeated DNA sequences may be related to the evolution of the primate lineage.
mesh_terms: D000818:Animals; D004262:DNA Restriction Enzymes; D004276:DNA, Satellite / Q000235:genetics*; D006071:Gorilla gorilla / Q000235:genetics; D006801:Humans; D006922:Hylobates / Q000235:genetics; D008297:Male; D009693:Nucleic Acid Hybridization; D002679:Pan troglodytes / Q000235:genetics; D011148:Pongo pygmaeus / Q000235:genetics; D011323:Primates / Q000235:genetics*; D013045:Species Specificity; D013154:Spleen
chemical_list: D004276:DNA, Satellite; D004262:DNA Restriction Enzymes