Progressive sensory neuropathy in patients without carcinoma: a disorder with distinctive clinical and electrophysiological findings.
Seven patients with severe progressive impairment of kinesthetic sense, mild dysfunction of cutaneous sense, and sparing of motor function were examined during a 3-year period. The clinical and electrophysiological findings are described in detail. None of these seven has had evidence of cancer despite a thorough investigation and a 3- to 16-year (average, 7 years) period of symptoms. These patients' symptoms were indistinguishable from those of patients with sensory neuropathy and coexistent carcinoma, suggesting that progressive sensory neuropathy is not invariably associated with carcinoma.
D000328:Adult; D000368:Aged; D001259:Ataxia / Q000503:physiopathology; D005260:Female; D006801:Humans; D007699:Kinesthesis; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D012677:Sensation