The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21 to qter.
We used a cloned cDNA probe for human growth hormone and Southern blotting techniques to analyze DNA from a series of rodent x human somatic cell hybrids for the presence of growth hormone-related sequences. Our results provide evidence for the assignment of the genes for growth hormone and chorionic somatomammotropin as well as a growth hormone-like gene to human chromosome 17. Analysis of mouse x human hybrid cells containing only part of the long arm of chromosome 17 enabled us to localize these genes to region 17q21 to 17qter.
D000818:Animals; D002874:Chromosome Mapping; D002902:Chromosomes, Human, 16-18; D004262:DNA Restriction Enzymes / Q000378:metabolism; D005796:Genes; D013006:Growth Hormone / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D009693:Nucleic Acid Hybridization; D010928:Placental Lactogen / Q000235:genetics*; D051381:Rats
D013006:Growth Hormone; D010928:Placental Lactogen; D004262:DNA Restriction Enzymes