Antagonism in action between mouse or human interferon and platelet growth factor.
Human leukocyte and mouse fibroblast interferons abolished the mitogenic effect of human or bovine platelet growth factor (PGF) on human or mouse cells. Conversely, the antiviral and anticellular activity of both forms of interferon was inhibited by PGF in the homologous and in certain heterologous cell systems.
D000818:Animals; D001792:Blood Platelets; D002417:Cattle; D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects*; D005347:Fibroblasts; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007962:Leukocytes; D051379:Mice; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D006133:Growth Substances; D007372:Interferons