Protein phosphorylations in poliovirus infected cells.
In vivo phosphorylation of proteins that are associated with polysomes of poliovirus-infected VERO (African green monkey kidney) and HeLa (Henrietta Lacks) cells differed from phosphorylations observed with uninfected cells that were fed fresh medium. With both types of cells infection stimulated phosphorylation of proteins with molecular weights of 40 000-41 000, 39 000, 34 000, 32 000, and 24 000. Similarities of phosphorylations in VERO and HeLa cells suggest that they are a specific consequence of infection and might serve a regulatory function during protein synthesis.
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D004591:Electrophoresis, Polyacrylamide Gel; D006367:HeLa Cells; D006801:Humans; D007668:Kidney; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000378:metabolism; D010750:Phosphoproteins / Q000096:biosynthesis; D010766:Phosphorylation; D017955:Poliovirus / Q000254:growth & development*; D011494:Protein Kinases / Q000378:metabolism; D012269:Ribosomal Proteins / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism
D009363:Neoplasm Proteins; D010750:Phosphoproteins; D012269:Ribosomal Proteins; D011494:Protein Kinases