Cell transformation in vitro by herpes simplex virus (HSV).
Data are presented on morphological and biochemical cell transformation in vitro induced by HSV. The results of some investigations on the oncogenic potential of different HSV strains, performed in the "Stefan S. Nicolau" Institute of Virology, are also reviewed. Several hypotheses concerning the mechanism of HSV-induced cell transformation in vitro are discussed.
D000818:Animals; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D006224:Cricetinae; D004622:Embryo, Mammalian; D066298:In Vitro Techniques; D009858:Oncogenic Viruses; D051381:Rats; D018139:Simplexvirus; D014776:Virus Cultivation