[Fatal case of metformin-induced lactic acidosis after urography in a diabetic patient (author's transl)].
The authors report a new case of lactic-acidosis in a diabetic patient receiving metformin. This patient, after urography developed an acute renal failure and a fatal lactic acidosis. Risks of urography in diabetic patients and guidelines for use of metformin are recalled; careful assessment of risk versus benefit for every proposed urography in diabetic patients never use metformin if creatinin is over 140 micromoles/liter, if an urography must be undergone, metformin must be stopped 3 days before urography and resumed only 3 days after it, if renal function allows it.
D000138:Acidosis / Q000139:chemically induced*; D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D007773:Lactates / Q000097:blood; D008687:Metformin / Q000009:adverse effects*; D014567:Urography / Q000009:adverse effects* / Q000379:methods
D007773:Lactates; D008687:Metformin
Acidose lactique mortelle après urographie intra-veineuse chez une diabétique recevant de la metformine.