Transfer of defective avian tumor virus genomes by a Rous sarcoma virus RNA packaging mutant.
SE21Q1b, a Rous sarcoma virus mutant which packages cellular rather than viral RNA, is competent for infection of quail cells and can transmit defective transforming retrovirus genes. Stably transformed recipient clones have been obtained by using this mutant.
D001355:Alpharetrovirus / Q000235:genetics*; D000818:Animals; D001358:Avian Sarcoma Viruses / Q000235:genetics*; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D003673:Defective Viruses / Q000235:genetics*; D011784:Quail; D014161:Transduction, Genetic; D014779:Virus Replication