The epinephrine-induced activation of the cardiac slow Ca2+ channel is mediated by the cAMP-dependent phosphorylation of calciductin, a 23 000 Mr sarcolemmal protein.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D000242:Cyclic AMP / Q000494:pharmacology*; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology*; D006352:Heart Ventricles / Q000378:metabolism; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D008565:Membrane Proteins / Q000378:metabolism*; D009124:Muscle Proteins / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010766:Phosphorylation; D012508:Sarcolemma / Q000378:metabolism*
D007473:Ion Channels; D008565:Membrane Proteins; D009124:Muscle Proteins; C032234:calciductin; D000242:Cyclic AMP; D002118:Calcium; D004837:Epinephrine