Mianserin: direct activation of brain norepinephrine neurons by blocking alpha 2-receptors.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D003000:Clonidine / Q000494:pharmacology; D003984:Dibenzazepines / Q000494:pharmacology*; D008125:Locus Coeruleus / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008803:Mianserin / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*
D003984:Dibenzazepines; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D008803:Mianserin; D003000:Clonidine; D009638:Norepinephrine