title: Diagnostic importance of immunological markers in lymphoma involving the central nervous system.
abstract: In an elderly woman, lymphoma involved the central nervous system and unusual nonlymphoreticular sites. Cerebrospinal fluid cell surface marker studies revealed a clone of malignant B cells. Studies of peripheral blood demonstrated a systemic disturbance of immune regulation similar to Epstein-Barr virus infections and the acquired immunodeficiency syndrome.
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D001402:B-Lymphocytes; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000276:immunology; D002555:Cerebrospinal Fluid / Q000166:cytology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008223:Lymphoma / Q000175:diagnosis* / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000502:physiology
chemical_list: D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D007136:Immunoglobulins