[Effect of an industrial-frequency electromagnetic field on protein biosynthesic processes of embryonal fibroblasts in tissue culture].
Using radioautography, the influence of the industrial frequency electromagnetic field (50 cps) (EMF i/f), with the tension of 50 and 150 kv/m was studied, on the synthesis of collagen and non-collagen proteins in cultured fibroblast-like human embryo cells in the presence and absense in the medium of adrenaline and of cyclic adenosine monophosphate (cAMP). The EMF depresses protein proportionally to its intesity and duration. The specific function of fibroblasts -- the synthesis of collagen -- is subject to this influence to a great extent. The preliminary administration of adrenaline or cAMP prevented the above changes. The cyclic AMP exerted a much stronger protective effect.
D003094:Collagen / Q000096:biosynthesis; D046508:Culture Techniques; D000242:Cyclic AMP / Q000494:pharmacology; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena / Q000009:adverse effects*; D004622:Embryo, Mammalian; D004837:Epinephrine / Q000494:pharmacology; D005347:Fibroblasts / Q000378:metabolism*; D006801:Humans; D011392:Proline / Q000378:metabolism; D014176:Protein Biosynthesis; D014364:Tryptophan / Q000378:metabolism
D014364:Tryptophan; D003094:Collagen; D011392:Proline; D000242:Cyclic AMP; D004837:Epinephrine
Vliianie élektromagnitnogo polia promyshlennoĭ chastoty na protsessy biosinteza belkov embrional'nymi fibroblastami v kul'ture tkani.