Efficient production of xenotropic murine leukemia virus unintegrated proviral DNA by cocultivation.
Cocultivation of virus-producing cells and homologous uninfected cells yielded greater than a 10-fold increase in linear and superhelical proviral DNAs as compared with previously published techniques.
D000406:AKR murine leukemia virus / Q000254:growth & development / Q000378:metabolism*; D000818:Animals; D002460:Cell Line; D004279:DNA, Viral / Q000096:biosynthesis*; D009052:Leukemia Virus, Murine / Q000378:metabolism*; D008828:Microbiological Techniques; D008907:Mink; D011995:Recombination, Genetic; D014776:Virus Cultivation
D004279:DNA, Viral