The electron spin resonance spectrum of a suicidal fungus.
The electron spin resonance spectrum of a suicidal inositol auxotroph of Neurospora crassa, previously used as a model of cellular aging, exhibits a high-spin Fe(III) signal whose intensity increases as a function of the mutant's "senescence". Surprisingly, the intensity of the signal is further enhanced by the exogenous antioxidant nordihydroguaiaretic acid, which reportedly decreases the rate of senescence.
D000975:Antioxidants / Q000494:pharmacology; D002396:Catechols / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D004578:Electron Spin Resonance Spectroscopy; D009637:Masoprocol; D009491:Neurospora / Q000378:metabolism*; D009492:Neurospora crassa / Q000187:drug effects / Q000378:metabolism*
D000975:Antioxidants; D002396:Catechols; D009637:Masoprocol