Adenosine depresses contractility and stimulates 3',5' cyclic nucleotide metabolism in the isolated frog ventricle.
D000241:Adenosine / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D002118:Calcium / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006352:Heart Ventricles / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D009200:Myocardial Contraction / Q000187:drug effects*; D011896:Rana temporaria
D000242:Cyclic AMP; D006152:Cyclic GMP; D000241:Adenosine; D002118:Calcium