Cell substrate for killed poliovaccine production.
The aspects of choice of cell substrate will be considered. The relative merits of primary cells, cell strains and cell lines will be considered from the standpoint of yield, safety and economics. The merits of highly purified antigen will be presented.
D000818:Animals; D000835:Animals, Wild; D002460:Cell Line; D000882:Haplorhini; D006367:HeLa Cells; D006801:Humans; D017955:Poliovirus / Q000254:growth & development*; D011054:Poliovirus Vaccine, Inactivated; D014776:Virus Cultivation / Q000379:methods*
D011054:Poliovirus Vaccine, Inactivated