Cell division in normal and transformed cells: the possible role of superoxide and hydrogen peroxide.
A unified theory of cell division is presented. This theory explains the division of both tumor cells and normal cells and involves superoxide radicals, hydrogen peroxide, glucose, cAMP, and cGMP.
D000818:Animals; D002455:Cell Division; D002462:Cell Membrane / Q000502:physiology; D002470:Cell Survival; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D000242:Cyclic AMP / Q000502:physiology; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis; D006801:Humans; D006861:Hydrogen Peroxide / Q000502:physiology*; D008099:Liver / Q000378:metabolism; D008928:Mitochondria / Q000502:physiology; D008962:Models, Theoretical; D010100:Oxygen / Q000502:physiology*; D012513:Sarcoma, Experimental / Q000503:physiopathology; D013481:Superoxides / Q000502:physiology*
D013481:Superoxides; D006861:Hydrogen Peroxide; D000242:Cyclic AMP; D005947:Glucose; D010100:Oxygen