[Effect of L-DOPA on cyclic adenosine-3',5'-monophosphate in neurogenically damaged cardiac muscle].
During electric stimulation of the aortal reflexogenic zone in rabbits, administration of L-DOPA prevented the reduction of the level of cyclic adenosine-3',5'-monophosphate (cAMP) in the cardiac muscle and blood plasma. This is likely to be related to L-DOPA ability to participate in the biosynthesis of endogenous catecholamines, and thus to stimulate the synthesis of cAMP.
D000818:Animals; D009202:Cardiomyopathies / Q000188:drug therapy* / Q000378:metabolism; D000242:Cyclic AMP / Q000032:analysis* / Q000097:blood; D004558:Electric Stimulation; D006321:Heart / Q000294:innervation; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D009206:Myocardium / Q000032:analysis*; D011817:Rabbits
D007980:Levodopa; D000242:Cyclic AMP
Vliianie L-DOFA na soderzhanie tsiklicheskogo adenozin-3',5'-monofosfata pri neĭrogennom povrezhdenii serdechnoĭ myshtsy.