title: [Endocarditis due to Hemophilus para-influenzae associated with mitral valve prolapses (author's transl)].
abstract: The authors report one observation of endocarditis due to Hemophilus para-influenzae associated with mitral valve prolapsus. This germ is difficult to isolate and is found late in cultures using standard techniques. The dicovery of germs resistant to ampicillin requires the search for the presence of a betalactamase. When resistant germs are found, the antibiotic of choice is chloramphenicol or cefamandole. This type of endocarditis different from the others on account of the risk major of embolism (60-85 p. 100) which justifies valve replacement when the echography reveals persistant vegetations.
mesh_terms: D000328:Adult; D002435:Cefamandole / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000188:drug therapy; D006192:Haemophilus Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008945:Mitral Valve Prolapse / Q000150:complications*
chemical_list: D002435:Cefamandole; D002701:Chloramphenicol
vernacular_title: Endocardite à Hemophilus para-influenzae sur prolapsus de la valve mitrale.