title: [Characteristics of adenohypophseal secretory activity in children with thymomegaly].
abstract: The radioimmunological method was applied in the study of ACTH, STH, and prolactin content in thymomegaly combined with pneumonia, and in practically healthy children. A comparative analysis of hormonal parameters depending on the functional condition of the thymus demonstrated a directly proportional correlation between the STH, prolactin level, and the thymus hyperplasia; there proved to be a reverse relationship between the ACTH level and thymomegaly. Hypoadrenocorticotropinemia, hypersomatotropinemia, and hyperprolactinemia could be used as diagnostic criteria in thymomegaly.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D002675:Child, Preschool; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007223:Infant; D008206:Lymphatic Diseases / Q000503:physiopathology; D008297:Male; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011014:Pneumonia / Q000503:physiopathology; D011388:Prolactin / Q000097:blood; D013950:Thymus Gland; D013952:Thymus Hyperplasia / Q000503:physiopathology
chemical_list: D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013006:Growth Hormone
vernacular_title: Osobennosti sekretornoĭ aktivnosti adenogipofiza u deteĭ s timomegalieĭ.