title: On the evolutionary relationship of the 4-alpha-helical heme proteins. The comparison of cytochrome b562 and cytochrome c'.
abstract: The atomic models of the cytochrome b562 and cytochrome c' monomers have been compared. When the respective heme groups are superimposed, the four alpha-helices of each nearly coincide. Four aromatic side chains, including the heme ligands, and a methionine occur in spatially equivalent positions in contact with the heme groups. This structural evidence suggests that the two cytochrome families may have diverged from a common molecular ancestor.
mesh_terms: D005075:Biological Evolution; D003573:Cytochrome b Group; D003574:Cytochrome c Group; D003580:Cytochromes; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D006420:Hemeproteins; D008958:Models, Molecular; D008970:Molecular Weight; D011487:Protein Conformation; D012246:Rhodospirillum
chemical_list: D003573:Cytochrome b Group; D003574:Cytochrome c Group; D003580:Cytochromes; D029968:Escherichia coli Proteins; D006420:Hemeproteins; C017850:cytochrome b562, E coli