Comparison of two delta-crystallin genes in the chicken.
Restriction endonuclease mapping and electron microscopy established that there are at least two nonallelic delta-crystallin genes in the chicken. The structure of a complete delta-crystallin gene has been deduced by analysis of five cloned fragments from the chicken genome. Fifteen intervening sequences compose approximately 80% of this gene; the other gene contains at least 14 intervening sequences. The mRNA gene sequences appear to be similar; at least 60% divergence was found between the intervening sequences of the two delta-crystallin genes. Insertions or deletions or both appear to be major events responsible for these differences.
D000818:Animals; D002645:Chickens / Q000235:genetics*; D003001:Cloning, Molecular; D003459:Crystallins / Q000235:genetics*; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004274:DNA, Recombinant; D005796:Genes; D009693:Nucleic Acid Hybridization
D003459:Crystallins; D004274:DNA, Recombinant; D004262:DNA Restriction Enzymes