[Modified method of isolating thymopoietin and its effect on neuromuscular transmission].
A modified method for isolation of the calf thymus hormone thymopoetin has been developed. For hormone purification high-speed multi-stage centrifugation and gel-filtration on sefadexes were used instead of filtration. The thymus hormonal factor was identified on the basis of its ability to block neuromuscular transmission.
D000818:Animals; D002417:Cattle; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003864:Depression, Chemical; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology; D009469:Neuromuscular Junction / Q000187:drug effects*; D009435:Synaptic Transmission / Q000187:drug effects*; D013946:Thymopoietins / Q000302:isolation & purification*; D013951:Thymus Hormones / Q000302:isolation & purification*; D014461:Ultracentrifugation; D014462:Ultrafiltration
D009466:Neuromuscular Blocking Agents; D013946:Thymopoietins; D013951:Thymus Hormones
Modifikatsiia metoda vydeleniia timopoétina i ego vliianie na nervno-myshechnuiu peredachu.