Late subcutaneous fibrosis following megavoltage radiotherapy.
A woman who received radiotherapy for a breast carcinoma developed symptomatic deep subcutaneous fibrosis 7 months after treatment. Deep biopsy confirmed the diagnosis. A good response to prednisone therapy was obtained in this patient. Long-term sequelae may include soft tissue sarcoma.
D001943:Breast Neoplasms / Q000209:etiology* / Q000532:radiotherapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000532:radiotherapy; D005260:Female; D005350:Fibroma / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*