Disulfiram neuropathy.
In four patients, sensorimotor polyneuropathy developed during treatment with disulfiram. Each patient began to improve with the cessation of treatment. Clinical, electrophysiologic, and pathologic observations point to a potentially reversible and probably dose-related axonal polyneuropathy.
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy; D002246:Carbon Disulfide / Q000009:adverse effects; D004221:Disulfiram / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D009186:Myelin Sheath / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology
D002246:Carbon Disulfide; D004221:Disulfiram