Simian virus 40 and Moloney-murine sarcoma virus infection of bona fide mouse epithelium.
Moloney-murine sarcoma virus (Moloney-MSV) and simian virus 40 (SV40) were found to infect successfully pure cultures of epithelial cells established from mouse liver and mammary tissue. MSV infection resulted in transient morphological foci with persistent production of infectious virus. SV40 infection produced detectable levels of virus-specific T antigen in the cells but morphological transformants were not observed.
D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D000957:Antigens, Viral, Tumor; D002460:Cell Line; D002472:Cell Transformation, Viral; D003673:Defective Viruses / Q000254:growth & development; D004847:Epithelial Cells; D004848:Epithelium; D006378:Helper Viruses / Q000254:growth & development; D008099:Liver; D008321:Mammary Glands, Animal; D051379:Mice; D008979:Moloney murine leukemia virus / Q000254:growth & development; D009053:Sarcoma Viruses, Murine / Q000254:growth & development*; D013539:Simian virus 40 / Q000254:growth & development*; D014776:Virus Cultivation; D014779:Virus Replication
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor