[Age sensitivity characteristics of the human and mouse chromosome apparatus in exposure to viral infection].
It is determined that the measles virus (vaccine strain Leningrad-16) induce cytogenetic alterations in bone marrow cells in all the examined mice, the most considerable aberrations being noted in newly born and especially aged mice. Coxsackie virus A13 is capable of causing cytogenetic aberrations in newly born and aged mice, while the puberal mice of the middle aged group are resistant to the mutagenic effect of the virus. Flu patients aged 65-80 and 2-5 years suffer from the biggest alterations in the blood chromosome leucocytes, with the decrease in number and in T-lymphocyte functional activity. The patients aged 18-35 years suffered less.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D003384:Coxsackievirus Infections / Q000235:genetics*; D004770:Enterovirus; D006801:Humans; D007251:Influenza, Human / Q000235:genetics* / Q000276:immunology; D008457:Measles / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C
Osobennosti vozrastnoĭ chuvstvitel'nosti khromosomnogo apparata cheloveka i mysheĭ pri vozdeĭstvii virusnoĭ infektsii.