[Donors and receptors of biologically labile methyl groups: characterization with a nicotinamide-trigonelline system].
The problem of transmethylations, the genesis of the labile methyl groups, the chemical structure of a transmethylating active substance are briefly explained and discussed. A methodology to characterize quickly the substances donor and acceptor of methyl groups is here described: it utilizes the ox crystalline lens in the presence of nicotinamide. The methodology is based on the irreversible system nicotinamide-trigonellinamide, by means of the vitamin B1 as catalyst.
D000470:Alkaloids / Q000378:metabolism*; D000818:Animals; D002417:Cattle; D007908:Lens, Crystalline / Q000378:metabolism*; D008745:Methylation; D009536:Niacinamide / Q000378:metabolism*; D013831:Thiamine / Q000378:metabolism
D000470:Alkaloids; D009536:Niacinamide; C009560:trigonelline; D013831:Thiamine
Donatori e accettori di gruppi metilici biologicamente labili: caratterizzazione mediante un sistema nicotinamide trigonellina.