The influence of alkali metal chlorides on environmentally-linked behavioural stereotypies in the rat.
In a series of three experiments using rats, the chlorides of lithium, rubidium and caesium were compared with sodium chloride in respect of their effects on behavioural stereotypy. Two apparatuses were used, a modified hold-board and an open field. Caesium was found to increase the occurrence of environmentally-linked behaviour in both types of apparatus. Lithium had effects in the opposite direction. Rubidium had effects like caesium in the modified hold-board test, but like lithium in the open field. The findings are discussed in terms of possible effects on central information processing mechanisms.
D000704:Analysis of Variance; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002586:Cesium / Q000494:pharmacology*; D002712:Chlorides / Q000494:pharmacology; D005106:Exploratory Behavior / Q000187:drug effects; D006801:Humans; D008094:Lithium / Q000494:pharmacology*; D018021:Lithium Chloride; D008124:Locomotion / Q000187:drug effects; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012413:Rubidium / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013239:Stereotyped Behavior / Q000187:drug effects*
D002712:Chlorides; D002586:Cesium; D012965:Sodium Chloride; D008094:Lithium; D018021:Lithium Chloride; C028019:cesium chloride; D012413:Rubidium