title: Further epidemiological investigations on subacute sclerosing panencephalitis (SSPE) in Romania.
abstract: The epidemiological study of 101 SSPE cases revealed the following aspects: a) an increase in the annual SSPE incidence, in relation to the improvement of detection possibilities; b) the preponderent involvement of male children and of children having experienced measles within the first 6-18 months of life; c) the high incidence of SSPE cases in families with several children, the patient being the 2nd or 3rd sibling; d) a mean interval of 50.1 +/- 32 months between acute measles and the onset of SSPE; e) the clustering of cases in terms of the epidemic year when acute measles had occurred. There were no modifications in SSPE epidemiology during the first 6 months after the initiation of mass antimeasles vaccination.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008459:Measles virus / Q000276:immunology; D009975:Orthomyxoviridae / Q000276:immunology; D018108:Respirovirus / Q000276:immunology; D012383:Romania; D012621:Seasons; D012737:Sex Factors; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology
chemical_list: D000914:Antibodies, Viral