Regulation of ovarian LH/HCG receptors in immature rats after injection of HCG.
In 24-day-old rats the reappearance of ovarian HCG-receptors up to day 4 after the injection of 200 IU HCG was due only to receptors in non-luteal cells. The receptor capacity increase observed on days 6 and 7 after the hormone injecion resulted from newly synthesized binding sites in luteinizing ovaries. Bromocriptine or an antiestrogen inhibited this receptor synthesis.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D005260:Female; D007986:Luteinizing Hormone; D010053:Ovary / Q000032:analysis*; D051381:Rats; D011956:Receptors, Cell Surface / Q000032:analysis; D013997:Time Factors
D006063:Chorionic Gonadotropin; D011956:Receptors, Cell Surface; D007986:Luteinizing Hormone