[Fungal infections -- always dangerous for immunosuppressed patients (author's transl)].
Four renal transplant recipients, treated with the immunosuppressive combination of azathioprine-prednisolone, developed organ or systemic mycoses caused by Candida albicans and, in one case, additionally by Trichophyton rubrum. Ketoconazole, a new wide-spectrum antimycotic drug, was successfully used in the treatment of the fungal infections in these patients. The oral route of administration, good tolerance and excellent results are good recommendations for this drug.
D000328:Adult; D002177:Candidiasis / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D007165:Immunosuppression Therapy; D007654:Ketoconazole; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy; D014005:Tinea / Q000188:drug therapy / Q000276:immunology*; D014184:Transplantation, Homologous
D007093:Imidazoles; D010879:Piperazines; D007654:Ketoconazole
Pilzinfektionen -- weiterhin gefährlich für den immunsuppressiv behandelten Patienten.