Y-maze behavior after an analog of ACTH 4--9, evidence for an attentional alteration.
Adult, male, Swiss-Webster mice were injected with either control solution or various doses of a long-acting analog of ACTH 4--9. The drug produced significant alterations in performance in an equiangular Y-maze. In comparison with control performance, both 25 and 50 micrograms/kg of drug produced a significant increase in repeated two-arm entries. This response pattern is consistent with the hypothesis that the drug produced a focusing of attention.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D001288:Attention / Q000187:drug effects*; D001522:Behavior, Animal / Q000187:drug effects*; D008297:Male; D051379:Mice; D010446:Peptide Fragments / Q000494:pharmacology*
D010446:Peptide Fragments; C028024:ACTH (4-9); D000324:Adrenocorticotropic Hormone