Localization of foot-and-mouth disease viral antigens in mammary gland of infected cows.
Virolactias as a result of foot-and-mouth disease infection in dairy cattle would indicate active virus replication in the bovine mammary gland. In the present study, virus was readily detected throughout the mammary gland by infectivity assay after cows were exposed to the virus either by aerosol or by a combination of intramammary-IV inoculation. Furthermore, immunofluorescent and hematoxylin and eosin staining of alternate frozen sections showed viral antigens in rounded alveolar cells with pyknotic nuclei.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D005537:Aphthovirus / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000382:microbiology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005536:Foot-and-Mouth Disease / Q000276:immunology; D008321:Mammary Glands, Animal / Q000276:immunology* / Q000382:microbiology; D008892:Milk / Q000276:immunology / Q000382:microbiology
D000956:Antigens, Viral