Lysine vasopressin attenuation of diethyldithiocarbamate-induced amnesia.
The effect of lysine vasopressin on diethyldithiocarbamate-induced amnesia for a step-through passive avoidance task was studied in rats. It was determined that although the hormone attenuates the amnesia when it is administered prior to retrieval testing, it fails to do so when it is injected prior to training. These results are consistent with the reports of others which demonstrate the reversal of diethyldithiocarbamate-induced amnesia by catecholamine agonists.
D000647:Amnesia / Q000139:chemically induced; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D004050:Ditiocarb / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D006801:Humans; D008236:Lypressin / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects*; D051381:Rats; D013859:Thiocarbamates / Q000037:antagonists & inhibitors*
D013859:Thiocarbamates; D008236:Lypressin; D004050:Ditiocarb