[Matrix activity of chromatin DNA and the adenylate cyclase system in the tissues of rats after a flight aboard biosatellite "Cosmos-936"].
Chromatin DNA template activity and cAMP metabolism enzymes in the liver and lymph organs of rats flown for 19 days were studied. Postflight RNA synthesis on the chromatin DNA template was increased in the liver and decreased in lymph organs. Adenylate cyclase and phosphodiesterase activities decreased in the liver and increased in lymph organs. No correlation between cAMP enzyme activity and chromatin DNA template activity was found. The nature of the biochemical changes in animal tissues is discussed.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002843:Chromatin / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D051381:Rats; D013026:Space Flight; D013154:Spleen / Q000201:enzymology / Q000378:metabolism*; D014158:Transcription, Genetic
D002843:Chromatin; D004247:DNA; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases
Matrichnaia aktivnost' DNK khromatina i adenilattsiklaznoĭ sistemy v tkaniakh krys posle poleta na biosputnike "Kosmos-936".