title: [New viewpoints on the pathophysiology and pathogenesis of arterial hypertension].
abstract: The pathophysiology and pathogenesis of the arterial hypertension can be explained from disturbances in the meshed regulating circle. Newer knowledge concerns the noradrenergic transformation of the excitation at the synapse. Concerning the humoral pressor systems we refer to the tonin-angiotensin-system, it is furthermore emphasized the disturbance in the sodium-potassium-transport on the membrane. The depressor systems -- prostaglandins, kallikrein-kinin-system -- will in future certainly bring newer knowledge concerning their participation in the pathogenesis of arterial hypertension. The practical importance of such findings should be taken into consideration in the formation of the long-term therapy of arterial hypertension.
mesh_terms: D000804:Angiotensin II / Q000502:physiology; D001692:Biological Transport; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007610:Kallikreins / Q000502:physiology; D007705:Kinins / Q000502:physiology; D009638:Norepinephrine / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011311:Pressoreceptors / Q000502:physiology*; D011453:Prostaglandins / Q000096:biosynthesis; D011941:Receptors, Adrenergic / Q000502:physiology*; D011942:Receptors, Adrenergic, alpha / Q000502:physiology*; D012701:Serotonin / Q000502:physiology; D012964:Sodium / Q000378:metabolism
chemical_list: D007705:Kinins; D011453:Prostaglandins; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D000804:Angiotensin II; D012701:Serotonin; D012964:Sodium; D007610:Kallikreins; D011188:Potassium; D009638:Norepinephrine
vernacular_title: Neuere Gesichtspunkte der Pathophysiologie und Pathogenese der arteriellen Hypertonie.