Quantitative study of human Scarpa's ganglion and vestibular sensory epithelia.
Methods for counting vestibular ganglion cells and determining the densities of hair cells and intraepithelial basophilic inclusions (IBI) in samples of cross-sectioned vestibular sensory epithelia are described. Data obtained by means of these methods in vestibular sensory epithelia and Scarpa's ganglia in individual temporal bones from subjects at different ages are presented. Both vestibular hair cells and nerve cells in Scarpa's ganglia are found numerically reduced in ears of aged individuals. Changes in the vestibular sensory epithelia appear to precede those seen in Scarpa's ganglion. The incidence of intraepithelial basophilic inclusions correlates with degeneration in the respective vestibular sensory epithelia. There are no striking differences in hair cells densities of the different vestibular sense organs of the same ear and from subjects at about the same age.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002452:Cell Count; D002648:Child; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D006198:Hair Cells, Auditory / Q000166:cytology; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008875:Middle Aged; D009474:Neurons / Q000166:cytology; D014725:Vestibular Nerve / Q000166:cytology*; D014722:Vestibule, Labyrinth / Q000166:cytology* / Q000648:ultrastructure