Entero-oxyntin: a stimulant of gastric acid secretion extracted from porcine intestine.
A peptide that further augments gastric acid secretion in cats, maximally stimulated by pentagastrin, was identified in porcine upper small intestine. Since the peptide stimulated basal and maximally pentagastrin-stimulated acid secretion to the same extent, it appears to act on a receptor different from the gastrin receptor and thus may be designated entero-oxyntin, a mediator of the intestinal phase of acid secretion.
D000818:Animals; D002415:Cats; D002766:Cholecystokinin / Q000032:analysis; D002850:Chromatography, Gel; D050556:Fatty Acid-Binding Proteins; D005750:Gastric Juice / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D005768:Gastrointestinal Hormones; D007421:Intestine, Small / Q000032:analysis; D010418:Pentagastrin / Q000494:pharmacology; D010455:Peptides / Q000032:analysis / Q000494:pharmacology*; D011956:Receptors, Cell Surface; D013270:Stomach / Q000502:physiology; D013552:Swine
D050556:Fatty Acid-Binding Proteins; D005768:Gastrointestinal Hormones; D010455:Peptides; D011956:Receptors, Cell Surface; C057275:fatty acid-binding protein 6; D002766:Cholecystokinin; D010418:Pentagastrin