[Effect of microiontophoretic applications of cortisol on hippocampal neuronal activity in experiments on freely moving rabbits].
In response to cortisole administration the majority of hormonesensitive hippocampal neurons increased ther firing rate in unrestrained rabbits. Apart from this, the hormone affected the interspike intervals distribution. Neurons with a lower spontaneous firing rate revealed a trend towards raise of hormone sensitivity. The data obtained corroborate the inhibitory role of the dorsal hippocampus in central mechanisms of regulation of hypophyseal corticotropic activity by the corticoids level.
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D001931:Brain Mapping; D004594:Electrophysiology; D006624:Hippocampus / Q000187:drug effects* / Q000502:physiology; D006854:Hydrocortisone / Q000008:administration & dosage / Q000494:pharmacology*; D007478:Iontophoresis; D008297:Male; D008845:Microinjections; D009043:Motor Activity / Q000502:physiology; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011817:Rabbits
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Vliianie mikroionoforeticheskikh applikatsiĭ kortizola na aktivnost' neĭronov gippokampa v opytakh na svobodnoperedvigaiushchikhsia krolikakh.