Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitroso-urea. Further evidence for the involvement of (ADP-ribose)n in DNA repair.
D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002499:Centrifugation, Density Gradient; D004260:DNA Repair / Q000187:drug effects*; D003841:Deoxycytidine / Q000494:pharmacology; D007939:Leukemia L1210 / Q000378:metabolism; D008770:Methylnitrosourea / Q000494:pharmacology*; D051379:Mice; D009536:Niacinamide / Q000031:analogs & derivatives / Q000494:pharmacology; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism*; D009713:Nucleotidyltransferases / Q000037:antagonists & inhibitors*; D011065:Poly(ADP-ribose) Polymerases; D013936:Thymidine / Q000494:pharmacology
D009607:Nitrosourea Compounds; D009702:Nucleoside Diphosphate Sugars; D003841:Deoxycytidine; D000246:Adenosine Diphosphate Ribose; D009536:Niacinamide; D008770:Methylnitrosourea; C024785:5-methylnicotinamide; D011065:Poly(ADP-ribose) Polymerases; D009713:Nucleotidyltransferases; D013936:Thymidine