Absorption and excretion of cholecalciferol and of 25-hydroxycholecalciferol and metabolites in birds.
The absorption and excretion in vivo of cholecalciferol or 25-hydroxycholecalciferol (25-HCC) were determined in chicks (Gallus domesticus) and turkeys (Meleagris gallopavo). The overall net cholecalciferol or 25-HCC absorption in chicks and cholecalciferol in turkey poults was 66.5 +/- 3.3, 74.9 +/- 3.7 and 83.6 +/- 7.1% of the intake, respectively. The absorption of cholecalciferol or 25-HCC in chicks and turkeys occurred at the upper part of the intestine. 25-HCC, esters and non-polar metabolites of cholecalciferol or 25-HCC, and their polar metabolites, were secreted in the duodenum of chicks and turkeys but were partially reabsorbed at the upper part of the jejunum.
D000818:Animals; D000831:Animals, Newborn; D002112:Calcifediol; D002645:Chickens / Q000378:metabolism*; D002762:Cholecalciferol / Q000502:physiology*; D006887:Hydroxycholecalciferols / Q000502:physiology*; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000502:physiology; D008297:Male; D013045:Species Specificity; D014422:Turkeys / Q000378:metabolism*
D006887:Hydroxycholecalciferols; D002762:Cholecalciferol; D002112:Calcifediol