Relationship between two voltage-dependent serotonin responses of molluscan neurones.
A serotonin (5-HT)-induced slow inward current was reanalyzed in identified snail neurones and found to result from a decrease in a voltage-dependent K+-conductance, sensitive to [Ca2+]0 changes. 5-HT evoked in the same neurones an increase in the spike plateau known to be associated to a K+-conductance decrease. Both 5-HT responses appear to reflect the same decrease in K+-conductance.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005071:Evoked Potentials; D005724:Ganglia / Q000166:cytology; D006372:Helix, Snails; D007473:Ion Channels / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D011188:Potassium / Q000378:metabolism; D012701:Serotonin / Q000502:physiology*
D007473:Ion Channels; D012701:Serotonin; D011188:Potassium; D002118:Calcium