Pleural granulocytes with cytoplasmic inclusions from patients with malignant lung tumours and mesothelioma.
Granulocytes with cytoplasmic inclusions (RA = Rheumatoid Arthritis cells) have previously been found in pleural effusions of rheumatoid and tuberculous origin. We now report the finding of RA-cells in effusions from patients suffering from bronchogenic carcinomas of the squamous-cell type and malignant mesothelioma. Such cells occurred only rarely in other types of primary or secondary lung tumour.
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D002283:Carcinoma, Bronchogenic / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003594:Cytoplasmic Granules / Q000473:pathology*; D005260:Female; D006098:Granulocytes / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D010996:Pleural Effusion / Q000166:cytology