Effect of thyroxine on the hepatic glycogen and glucose-6-phosphatase activity of developing rats.
The influence of exogenous thyroxine was studied on the hepatic glycogen content and glucose-6-phosphatase activity of rats of different age groups. The glycogen content and glucose-6-phosphatase activity were found to be decreased in the livers of 5, 15, 30 and 60-day-old rats after thyroxine treatment. In normal rats of 5, 15, 30 and 60-day-old, a gradual rise in both the hepatic glycogen content and glucose-6-phosphatase activity was noted as the age advanced from immature to adult.
D000375:Aging; D000818:Animals; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D008099:Liver / Q000187:drug effects; D008112:Liver Glycogen / Q000378:metabolism*; D008297:Male; D051381:Rats; D013974:Thyroxine / Q000494:pharmacology*
D008112:Liver Glycogen; D005952:Glucose-6-Phosphatase; D013974:Thyroxine