[Effect of 5'-adenosine monophosphate and cyclic 3',5'-adenosine monophosphate on the ability of guinea pig bone marrow precursor cells to form fibroblast-like cell colonies in vitro].
The effect of 5'-AMP and cyclic 3',5'-AMP on the ability of cells--precursors of bone marrow to form colonies of fibroblast-like cells in vitro was studied in the guinea pig. No reliable effect of both substances (within the limits of 10(-5) to 10(-8) M) on the formation of fibroblast colonies in vitro by the cells--precursors of bone marrow was shown. No differences were established in the size of colonies between the experimental and control variants.
D000249:Adenosine Monophosphate / Q000494:pharmacology*; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D003114:Colony-Forming Units Assay; D000242:Cyclic AMP / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D008297:Male
D000249:Adenosine Monophosphate; D000242:Cyclic AMP
Vliianie 5'-adenozinmonofosfata i tsiklicheskogo 3',5'-adenozinmonofosfata na sposobnost' kletok-predshestvennikov kostnogo mozga morskoi svinki obrazovyvat' kolonii fibroblastopodobnykh kletok in vitro.