title: [The radiation dose to children bone scintigraphy with 99mTc-phosphate compounds (author's transl)].
abstract: In order to determine the radiation dose to children during bone scintigraphy, distribution and excretion measurements on 99mTc-pyrophosphate and 99mTc-diphosphonate were carried out in rats, piglets, children and adults. Because of the more intensive bone metabolism in children, uptake of 43 to 47% is higher than in adults, in whom uptake in the skeleton reaches 33 to 36%. Assuming homogenous distribution of uptake, radiation dose to the skeleton in children of the ages investigated was 51 to 55 mrd per mCi. Bearing in mind the non-homogeneous distribution in the juvenile skeleton, radiation dose at growth point reaches 85 to 95 mrd per mCi.
mesh_terms: D000328:Adult; D000367:Age Factors; D000818:Animals; D001835:Body Weight; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000528:radiation effects; D002648:Child; D011756:Diphosphates / Q000378:metabolism; D004164:Diphosphonates / Q000378:metabolism; D006207:Half-Life; D006614:Hindlimb; D006801:Humans; D010710:Phosphates / Q000097:blood / Q000378:metabolism*; D011829:Radiation Dosage; D011877:Radionuclide Imaging; D051381:Rats; D013667:Technetium / Q000097:blood / Q000378:metabolism*; D013977:Tibia / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D011756:Diphosphates; D004164:Diphosphonates; D010710:Phosphates; D013667:Technetium
vernacular_title: Strahlenbelastung des Kindes bei der Knochenszintigraphie mit 99mTc-markierten Phosphatverbindungen.