Bovine leukemia virus-specific antibodies in French cattle. III. Prevalence of the BLV-gp 51 radioimmunoassay for the detection of BLV-infected animals.
The control of the spread of BLV infection among cattle requires very sensitive methods of detection. The BLV-gp51 radioimmunoassay presents great advantages over the other serological methods, including the BLV-p24 radioimmunoassay. This is clear from studies of normal animals from the high-leukemia-incidence region which show that anti-gp51 antibodies reach higher titers than anti-p24 or may even exist alone. Moreover, a sequential survey reveals that the anti-gp antibodies appear earlier. On the other hand, it was not possible to detect a viral antigen expression in the tissues of the infected animals.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000918:Antibody Specificity; D000956:Antigens, Viral / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000276:immunology; D005602:France; D007938:Leukemia / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D001909:Leukemia Virus, Bovine / Q000276:immunology*; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology / Q000662:veterinary; D011863:Radioimmunoassay / Q000379:methods*; D012190:Retroviridae / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral