Effect of theophylline on binding of L-triiodothyronine (T3) to cytosolic receptors of human leukocytes.
Effect of theophylline on T3 binding in the cytosol receptors of human leukocytes was investigated by charcoal-dextran assay. The presence of 15 mM theophylline increases about 2-fold the apparent association constants (KA) without affecting the total number of binding sites (N).
D003600:Cytosol; D006801:Humans; D066298:In Vitro Techniques; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000378:metabolism; D013806:Theophylline / Q000494:pharmacology*; D014284:Triiodothyronine / Q000378:metabolism*
D011956:Receptors, Cell Surface; D014284:Triiodothyronine; D013806:Theophylline