title: Role of two particle types in bovine rotavirus morphogenesis.
abstract: The involvement of light (L) and dense (D) bovine rotavirus particle types during virus replication has been studied. It was found that infectious parental L virions are uncoated in vivo to a particle similar to native D particles. Differences in the rate of synthesis and relative yields of L and D particles in MDBK and MA-104 cells have been detected. Results from pulse-chase labeling experiments indicate that D particles serve as morphogenic precursors to the complete L virion.
mesh_terms: D000818:Animals; D002417:Cattle; D002460:Cell Line; D007700:Kinetics; D009024:Morphogenesis; D012328:RNA Viruses / Q000254:growth & development*; D012401:Rotavirus / Q000254:growth & development*; D014771:Virion / Q000032:analysis / Q000254:growth & development*