title: [Delayed skin sensitivity in cattle against adenovirus antigen].
abstract: An investigation was carried out concerning the allergic sensitivity of a delayed type with cows infected with adenoviruses. The experiments were made on 30 heads of cattle between the age of 3 and 6, 3 out of which by intradermal injecting of concentrated adenoviral antigen with serotype 1 in a quantity 0.2 cm3 into the neck, whereas on the opposite side an applied control antigen was used. The results were accounted for visually through palpation and measuring of the thickness of the skin fold before the experiment and 24, 48, 72 and 96 hours after the injection. As a positive skin allergic reaction was adopted that one during which a swelling was noticed in the spot of the injected antigen from a distance and through palpation it proved tempered and sore, whereas the difference in thickness of the skin fold before the experiment and 48 hours after the injection of the antigen was over 2.5 mm. With 17 cows out of the 30 treated cows changes were found proving a positive allergic reaction with a most pronounced character in the 48th hour. On the spot of application of the control antigen there were no data of a positive reaction. A certain parallelism was proved. A conclusion was drawn out that the skin allergy reaction could be used for a herd diagnosis of adenoviral infections with cows.
mesh_terms: D000256:Adenoviridae / Q000276:immunology*; D000257:Adenoviridae Infections / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000662:veterinary*; D012867:Skin / Q000276:immunology*; D013997:Time Factors
chemical_list: D000956:Antigens, Viral
vernacular_title: Kozhna chuvstvitelnost ot zabaven tip pri goveda sreshtu adenovirusen antigen.