title: Carcinoma of major salivary glands.
abstract: Ninety-four patients with carcinoma of the major salivary glands seen at Indiana University Hospitals from 1960-1977 were studied. Eighty-four patients completed their planned course of therapy, and 49 of 84 patients remain alive with no evidence of disease 2-17 years following treatment. Comparison has been made for three modalities: surgery alone, radiation therapy alone, and a combined approach. Surgery alone was used for treatment of early lesions, and 22 of 38 patients (58%) remain free of disease. Radiation therapy alone was used for advanced cases and palliation, and 6 of 16 patients (37.5%) remain free of disease. In the combination treatment, 21 of 30 patients (70%) are alive and free of disease. In the combination treatment, 21 of 30 patients (70%) are alive and free of disease from 2-17 years after treatment. Ten patients did not complete treatment and all of these patients died of disease.
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D011832:Radiation Injuries; D011882:Radiotherapy, High-Energy; D012075:Remission, Spontaneous; D012468:Salivary Gland Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D013361:Sublingual Gland; D013363:Submandibular Gland; D013997:Time Factors; D014987:Xerostomia / Q000209:etiology