title: [Cell membrane mechanism of action of prostaglandins E1 and F2 alpha on thrombocyte function].
abstract: PGE1 and PGF2 alpha were shown to exert an opposite action on Na, K-ATPase activity and protein fluorescence of the platelet membranes. The effect of the prostaglandins appeared to be unidirectional as regards the erythrocytic membranes. The prostaglandins were demonstrated to increase viscosity of the lipid bilayer and its permeability by uni- and bivalent cations.
mesh_terms: D001792:Blood Platelets / Q000187:drug effects*; D002462:Cell Membrane / Q000187:drug effects; D002463:Cell Membrane Permeability / Q000187:drug effects; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D011458:Prostaglandins E / Q000494:pharmacology*; D011460:Prostaglandins F / Q000494:pharmacology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D008565:Membrane Proteins; D011458:Prostaglandins E; D011460:Prostaglandins F; D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: Kletochno-membrannye mekhanizmy deĭstviia prostaglandinov E1 i F2 alpha na funktsional'noe sostoianie trombotsitov.