Sodium activation of heart (Na+ + K+)-ATPase from normotensive and spontaneously hypertensive rats.
The sodium activation of heart (Na+ + K+)-ATPase has been studied in a microsomal fraction prepared from hearts of normotensive and spontaneously hypertensive Wistar rats. The results show that the apparent affinity of the transport enzyme for sodium was lower in hypertensive than in normotensive rats.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D006973:Hypertension / Q000201:enzymology*; D066298:In Vitro Techniques; D007700:Kinetics; D009206:Myocardium / Q000201:enzymology*; D009929:Organ Size; D051381:Rats; D012964:Sodium / Q000494:pharmacology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase