[Complications after perhexiline maleate and amiodarone chlorhydrate treatment in a same patient: hypoglycemia, polyneuritis and hyperthyroidism (author's transl)].
The authors report the case of a 65 year old man treated with amiodarone chlorhydrate since 4 years and perhexiline maleate since 15 months, admitted for constitutional symptoms with fever, neurologic troubles particularly polyneuritis and pronounced hypoglycemia. A diagnostic of hyperthyroidism was made and attributed to amiodarone. The hypoglycemia and the polyneuritis were related to perhexiline maleate as other signs presented by the patient. All the symptoms disappeared after discontinuation of the drugs. The complications secondary to maleate perhexiline administration are reviewed.
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D001572:Benzofurans / Q000009:adverse effects*; D001835:Body Weight; D056486:Chemical and Drug Induced Liver Injury; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced*; D007003:Hypoglycemia / Q000139:chemically induced* / Q000378:metabolism; D008297:Male; D009422:Nervous System Diseases / Q000139:chemically induced; D010480:Perhexiline / Q000009:adverse effects*; D010880:Piperidines / Q000009:adverse effects*; D011129:Polyradiculoneuropathy / Q000139:chemically induced*
D001572:Benzofurans; D010880:Piperidines; D010480:Perhexiline; D000638:Amiodarone
Complications du maléate de perhexiline et du chlorhydrate d'amiodarone chez le même sujet: hypoglycémie, polynévrite et hyperthyroïdie.