title: Hind III restriction site map of the human adenovirus type 1 DNA.
abstract: The physical map of human adenovirus type 1 DNA was constructed with the Hind III restriction enzyme. Direct comparison of the DNA fragments with those of adenovirus type 2 revealed that the genome of adenovirus type 1 is 200 to 300 base pairs longer. The difference are located outside the region of the inverted terminal repetition within three distinct loci. Fragment Hind III-F of type 1 DNA which is presumed to carry all the genes responsible for in vitro transformation can be separated without considerable contamination by a single electrophoretic step.
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D001482:Base Composition; D007446:Chromosome Inversion; D002874:Chromosome Mapping; D004261:DNA Replication; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes