Variations in levels of cyclic AMP and GMP in the thymus, spleen and mesenteric lymph node of rats after the induction of adjuvant arthritis.
The development of adjuvant arthritis induced important modifications in intracellular levels of cyclic AMP and GMP in primary and secondary lymphoid organs: a continuous decrease in cyclic AMP and a biphasic increase in the level of cyclic GMP which correlate well with the onset of the acute phase and the systemization of the disease.
D000818:Animals; D001168:Arthritis / Q000378:metabolism*; D001169:Arthritis, Experimental / Q000378:metabolism*; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D008198:Lymph Nodes / Q000032:analysis; D008643:Mesentery / Q000032:analysis; D051381:Rats; D013154:Spleen / Q000032:analysis; D013950:Thymus Gland / Q000032:analysis
D000242:Cyclic AMP; D006152:Cyclic GMP