Parathyroid hormone, cAMP, electrolytes and uric acid after high dose CaCl2 in patients with idiopathic stone formation.
High dose levels of calcium chloride significantly decrease serum level of parathyroid hormone (PTH) in both patients with history of idiopathic stone formation and healthy controls. Suppressibility of parathyroid glands is obtained by injection of 10 ml 10% calcium chloride without any restriction in calcium diet. Serum levels of calcium measured 14 mg/dl 10 min. after high dose calcium chloride injection and distinctly affect cAMP in urine in patients when compared to healthy controls. The elimination of electrolytes and uric acid is elevated 40 min. after calcium application in both patients and controls and returns to normal values 120 min. later. No stone formation has been observed in an eighteen mouth follow up of all subjects studied.
D000328:Adult; D002118:Calcium / Q000097:blood; D002122:Calcium Chloride; D000242:Cyclic AMP / Q000032:analysis*; D004573:Electrolytes / Q000652:urine*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine; D014527:Uric Acid / Q000652:urine*; D014545:Urinary Calculi / Q000503:physiopathology*
D004573:Electrolytes; D010281:Parathyroid Hormone; D014527:Uric Acid; D012964:Sodium; D000242:Cyclic AMP; D002122:Calcium Chloride; D011188:Potassium; D002118:Calcium