Familial thyroid nodulation and arrhenoblastoma.
A patient who had thyroid nodules and a functioning ovarian arrhenoblastoma had a family history of thyroid nodulation affecting both males and females in four consecutive generations. One relative had multiple follicular adenomas of the thyroid. The findings support the proposal that this is another genetically determined endocrine organ tumor complex.
D000236:Adenoma / Q000150:complications / Q000235:genetics*; D000293:Adolescent; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D010051:Ovarian Neoplasms / Q000150:complications*; D010375:Pedigree; D018310:Sertoli-Leydig Cell Tumor / Q000150:complications*; D013964:Thyroid Neoplasms / Q000150:complications / Q000235:genetics*