[Therapeutic effect of a saline solution with sodium lactate (lactasol) in traumatic shock].
Acute experiments on 67 adult dogs have demonstrated that infusions of lactasol in a dose of 25 ml/kg in the early period and in a dose of 50 ml/kg in the late period of shock are not efficacious enough. Injection of the increased amount of the saline in the early and late period of shock (up to 50 and up to 100 ml/kg, respectively) makes it possible to save from death almost all the animals. A conclusion is made that the therapeutic effect of lactasol depends on the amount of the saline injected and on the period of shock during which the saline is injected, as well as on the specific action of sodium lactate.
D000818:Animals; D001639:Bicarbonates / Q000008:administration & dosage; D002122:Calcium Chloride / Q000008:administration & dosage; D004285:Dogs; D005260:Female; D007263:Infusions, Parenteral / Q000379:methods; D007773:Lactates / Q000008:administration & dosage*; D008274:Magnesium / Q000008:administration & dosage; D015636:Magnesium Chloride; D008297:Male; D011189:Potassium Chloride / Q000008:administration & dosage; D012774:Shock, Traumatic / Q000188:drug therapy*; D017693:Sodium Bicarbonate; D012965:Sodium Chloride / Q000008:administration & dosage
D001639:Bicarbonates; D007773:Lactates; D015636:Magnesium Chloride; D012965:Sodium Chloride; D011189:Potassium Chloride; D017693:Sodium Bicarbonate; D008274:Magnesium; D002122:Calcium Chloride
Lechebnyĭ éffekt solevogo rastvora s laktatom natriia (laktasola) pri travmaticheskom shoke.