title: Morphogenetic effects of light and guanine derivatives on the fruiting myxobacterium Stigmatella aurantiaca.
abstract: When low cell densities of the myxobacterium Stigmatella aurantiaca were starved on an inorganic salts and agar medium, cell aggregation and fruiting body formation showed a striking dependency upon the presence of light. This dependency was not manifested when sufficient amounts of guanosine or guanine nucleotides were added to the medium. Light interacted cooperatively with suboptimal concentrations of guanine compounds to promote development. None of the other purine or pyrimidine derivatives, with the exception of adenine, stimulated development. However, aggregates that formed in the presence of adenine did not mature into fruiting bodies and instead disaggregated.
mesh_terms: D006150:Guanine Nucleotides / Q000494:pharmacology*; D006151:Guanosine / Q000494:pharmacology*; D006157:Guanosine Monophosphate / Q000494:pharmacology; D008027:Light; D009024:Morphogenesis; D009231:Myxococcales / Q000166:cytology / Q000254:growth & development*; D011685:Purine Nucleotides / Q000494:pharmacology; D011742:Pyrimidine Nucleotides / Q000494:pharmacology
chemical_list: D006150:Guanine Nucleotides; D011685:Purine Nucleotides; D011742:Pyrimidine Nucleotides; D006151:Guanosine; D006157:Guanosine Monophosphate