Meningeal carcinomatosis in breast cancer presenting as central hypoventilation: a case report with a brief review of the literature.
Meningeal carcinomatosis can appear with a variety of neurologic signs and symptoms. Alterations in respiratory control have not been reported in this syndrome or in neurologic syndromes associated with systemic cancer. The authors report on a case of documented leptomeningeal carcinoma from breast cancer presenting as apnea; they note its successful treatment with radiation and intrathecal chemotherapy. The authors conclude that respiratory failure can be considered as part of the syndrome of leptomeningeal carcinomatosis.
D000368:Aged; D001049:Apnea / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000556:secondary*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D007040:Hypoventilation / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000556:secondary*