Spenolimycin, a new spectinomycin-type antibiotic. I. Discovery, taxonomy and fermentation.
Spenolimycin, a new spectinomycin-type antibiotic, was discovered in the fermentation broth of a new actinomycete named Streptomyces gilvospiralis sp. nov. strain AB634D-177. Although a small amount of spectinomycin is coproduced by strain AB634D-177, the culture is different from other known spectinomycin-producing actinomycetes. Spenolimycin was obtained by conventional submerged culture in 14-liter fermentors with a peak antibiotic titer of 140 micrograms/ml.
D005285:Fermentation; D000198:Spectinomycin / Q000031:analogs & derivatives* / Q000302:isolation & purification; D013302:Streptomyces / Q000145:classification* / Q000378:metabolism
D000198:Spectinomycin; C044528:spenolimycin