title: Use of preoperative chemotherapy and radiation therapy in patients with Wilm's tumors.
abstract: Four patients underwent preoperative chemotherapy and radiotherapy for Wilm's tumor, and three were without pathological diagnosis. Three of the four are currently free of disease. Patients with massive abdominal tumors and with the clinical and radiological characteristics of Wilm's tumor should receive preoperative chemotherapy and radiation. This treatment plan should provide the best chance of resectability and will, it is hopes, improve the chance of survival in these children.
mesh_terms: D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D014750:Vincristine / Q000008:administration & dosage; D009396:Wilms Tumor / Q000628:therapy*
chemical_list: D003609:Dactinomycin; D014750:Vincristine