[Rational method for producing sera with high titers of virus-neutralizing antibodies. Part III].
The effect of a number of nonspecific stimulators of immunogenesis (complete-Freund's adjuvant, complete adjuvant prepared from Soviet made components, arlacel with vaseline oil, aluminium hydroxide) on the immune process has been studied. The highest titers of virus-neutralizing antibodies have been obtained with the use of complete Freund's adjuvant land complete adjuvant prepared from Soviet components (X=1 : 54040 and X=1 : 40960, respectively).
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000536:Aluminum Hydroxide / Q000494:pharmacology; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D003168:Complement Fixation Tests; D005620:Freund's Adjuvant / Q000494:pharmacology; D009500:Neutralization Tests; D010577:Petrolatum / Q000494:pharmacology; D017955:Poliovirus / Q000276:immunology*; D011817:Rabbits / Q000276:immunology
D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D000536:Aluminum Hydroxide; D010577:Petrolatum; D005620:Freund's Adjuvant
Ratsional'nyĭ metod polucheniia syvorotok s vysokimi titrami virusneĭ tralizuiushchikh antitel. Soobshchenie III.