(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.
D000818:Animals; D001418:Baclofen / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects*; D002531:Cerebellum / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects; D003342:Corpus Striatum / Q000187:drug effects; D004298:Dopamine / Q000378:metabolism; D066298:In Vitro Techniques; D009433:Neural Inhibition / Q000187:drug effects; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000187:drug effects* / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D017981:Receptors, Neurotransmitter; D012701:Serotonin; D005680:gamma-Aminobutyric Acid; D001418:Baclofen; D004298:Dopamine; D009638:Norepinephrine