Non-specific, non-selective and mild increase in the latency of pentylenetetrazol seizures produced by large doses of the putative endogenous ligands of the benzodiazepine receptor.
D000818:Animals; D007042:Hypoxanthines / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D007276:Injections, Intraventricular; D007288:Inosine / Q000494:pharmacology; D008024:Ligands; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009536:Niacinamide / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000494:pharmacology*; D011955:Receptors, Drug / Q000187:drug effects*; D011963:Receptors, GABA-A; D012640:Seizures / Q000139:chemically induced*; D013997:Time Factors
D007042:Hypoxanthines; D008024:Ligands; D011955:Receptors, Drug; D011963:Receptors, GABA-A; D009536:Niacinamide; D007288:Inosine; D010433:Pentylenetetrazole