[Role of ACTH and corticosteroids in the aggressive-defensive behavior of rats].
Judging by the thresholds of the squeak, rising and fight reactions, the fight reaction frequency and threat standing reaction to shock--induced aggression in rats, the ACTH enhanced the fear response and fight behaviour both in normal and adrenalectomized rats. Removal of the adrenal glands facilitated the shock--induced aggression whereas hydrocortisone and DOCA caused the opposite effect. The ACTH seems to produce a direct extraadrenal effect on the brain structures thus inducing the formation of irritable aggression.
D000305:Adrenal Cortex Hormones / Q000502:physiology*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000374:Aggression / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D003900:Desoxycorticosterone / Q000494:pharmacology*; D004597:Electroshock; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D051381:Rats
D000305:Adrenal Cortex Hormones; D003900:Desoxycorticosterone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Rol' AKTG i kortikosteroidov v aggressivno-oboronitel'nom povedenii krys.