Comparison of a low and high dose ACTH gel in the treatment of hay fever.
The present data show that in fourteen patients treated with 200 iu Acthar gel, hay fever symptoms were less during the period of peak pollen challenge during June, than those experienced by an equivalent group treated with 80 iu. Analysis of the data showed that in the seven worst sufferers in both groups the difference between treatments was statistically significant (P=0.033, estimated by analysis of covariance of the symptom scores over the period of peak pollen challenge). No serious side effects were noted in patients from either group.
D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage* / Q000627:therapeutic use; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007273:Injections, Intramuscular; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy* / Q000276:immunology
D007073:Immunoglobulin E; D000324:Adrenocorticotropic Hormone