Regional cyclic AMP levels in homogenates of rat brain after ketalar and trifluoperazine.
There was a significant fall in cAMP levels after administration of TFP or ketalar. Different amounts of cAMP were present in different regions of rat brain. Concentrations of cAMP in different regions of the rat brain were found to decrease in the following order: cerebrum > thalamus with hypothalamus > midbrain  > hippocampus > cerebral cortex.
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D000242:Cyclic AMP / Q000032:analysis*; D005260:Female; D066298:In Vitro Techniques; D007649:Ketamine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D014268:Trifluoperazine / Q000494:pharmacology*
D014268:Trifluoperazine; D007649:Ketamine; D000242:Cyclic AMP