Detection of cytomegalovirus genomes in human skin fibroblasts by DNA hybridization.
A previous isolation of a human cytomegalovirus (CMV) from fibroblasts derived from intact skin of a Charcot-Marie-Tooth disease patient has prompted examination of six blind-coded cultured human skin lines by CMV DNA hybridization. The detection of CMV genome equivalents in three of the lines suggests that, in some cases, intact human skin may be a site of CMV latency.
D002460:Cell Line; D003587:Cytomegalovirus / Q000235:genetics*; D004279:DNA, Viral / Q000032:analysis*; D005347:Fibroblasts / Q000382:microbiology; D006801:Humans; D009693:Nucleic Acid Hybridization; D012867:Skin
D004279:DNA, Viral