title: A trial manufacture of a motor-driven laser light scattering optic for whole bladder wall irradiation.
abstract: The detection of CIS of the bladder by fluorescence endoscopy with hematoporphyrin derivative (HpD) and argon ion laser was performed using a video monitoring system coupling with an image intensifier; however, it was difficult because of the reflecting light of the excitation light. Whole bladder wall photoradiation therapy was carried out in 3 patients with multicentric CIS of the bladder, using argon-dye laser light (630 +/- 1.6 nm) of 5 to 25 J/cm2. The anticancer effect of this therapy was followed by urinary cytology and clusters of vacuolated cancer cells were observed for 2 days after the therapy.
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000188:drug therapy; D020684:Cystoscopes; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007834:Lasers; D008297:Male; D010778:Photochemotherapy / Q000295:instrumentation*; D012542:Scattering, Radiation; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D006415:Hematoporphyrins; D017324:Hematoporphyrin Derivative