Purine-containing compounds, including cyclic adenosine 3',5'-monophosphate, induce fruiting of Myxococcus xanthus by nutritional imbalance.
Induction of Myxococcus xanthus fruiting by a number of different purine-containing compounds, including cyclic adenosine 3',5'-monophosphate, is defective in a mutant resistant to 2,6-diaminopurine. Furthermore, the purine-induced fruiting of wild-type cultures is uniquely blocked by a low concentration of added glycine. These results imply that different purine-containing compounds induce fruiting through a single mechanism involving nutritional imbalance.
D000225:Adenine / Q000494:pharmacology; D000241:Adenosine / Q000494:pharmacology; D000242:Cyclic AMP / Q000494:pharmacology*; D005998:Glycine / Q000494:pharmacology; D007042:Hypoxanthines / Q000494:pharmacology; D009231:Myxococcales / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D011687:Purines / Q000494:pharmacology*
D007042:Hypoxanthines; D011687:Purines; D000242:Cyclic AMP; D000225:Adenine; D000241:Adenosine; D005998:Glycine