title: Anti-dsDNA antibodies in sera of patients without systemic lupus erythematosus.
abstract: 133 sera of patients without systemic lupus erythematosus (SLE) have been analyzed by an ultramicro ELISA for antibodies to dsDNA. 14 sera (10.5%) had antibody concentrations greater than 120 mU/ml ("positive"). Additionally, 29 sera (21.5%) had antibodies within the range 60 . . . 120 mU/ml ("borderline"). Pathogenetic significance is discussed briefly.
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis*; D003095:Collagen Diseases / Q000276:immunology; D004247:DNA / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*
chemical_list: D000974:Antibodies, Antinuclear; D004247:DNA