The triphasic reduction of cytochrome b in the succinate-cytochrome c reductase.
In the succinate-cytochrome c reductase, the reduction of cytochrome b has been found to be triphasic: an initial rapid partial reduction was followed first by a rapid oxidation and then finally by a slow reduction. The initial reduction of cytochrome b was faster than that of cytochrome c1 and the final slow reduction of cytochrome b began when cytochrome c1 reduction was approaching completion. In presence of the inhibitors antimycin A or HQNO the reduction of cytochrome b became monophasic. Hysteresis or a kinetic cooperative effect of a factor controlling cytochrome b oxidation has been suggested as a possible explanation for the triphasic reduction of cytochrome b.
D000818:Animals; D003573:Cytochrome b Group; D003580:Cytochromes / Q000378:metabolism*; D003575:Cytochromes c1 / Q000378:metabolism; D007700:Kinetics; D009206:Myocardium / Q000378:metabolism; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D013053:Spectrophotometry; D013384:Succinate Cytochrome c Oxidoreductase / Q000378:metabolism*; D013552:Swine
D003573:Cytochrome b Group; D003580:Cytochromes; D003575:Cytochromes c1; D010088:Oxidoreductases; D013384:Succinate Cytochrome c Oxidoreductase