Chemical modification of carotid body chemoreception by sulfhydryls.
Sulfhydryl reagents cause striking augmentation of the chemoreceptor responses of the carotid body to hypoxia. This indicates that a cellular plasma membrane protein with a reactive sulfhydryl group is a constituent part of the chemoreceptor architecture and provides a means of identification, localization, and isolation of the protein.
D002731:4-Chloromercuribenzenesulfonate / Q000494:pharmacology; D000818:Animals; D002344:Carotid Body / Q000187:drug effects / Q000502:physiology*; D002415:Cats; D002462:Cell Membrane / Q000502:physiology; D002628:Chemoreceptor Cells / Q000187:drug effects / Q000502:physiology*; D005033:Ethylmaleimide / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000494:pharmacology*
D013438:Sulfhydryl Compounds; D002731:4-Chloromercuribenzenesulfonate; D005033:Ethylmaleimide