[Scintigraphy with 99mTc-methylene diphosphonate for the detection and localization of rhabdomyolysis].
In 24 patients with biochemically proven rhabdomyolysis 34 scans with 99mTc-MDP were performed to detect regional as well as generalized myolysis. When performing the scan within 10 days after the maximum of myolysis, scintigraphic detection was possible in 95% of the patients, but after 20 days in none. Regional tracer accumulation in muscles was more frequent (89%) than generalized diffuse accumulation (31%). Predominantly muscles of the thigh, the buttocks and the upper arm were involved. Diffuse tracer accumulation in both kidneys occurred in 75% of patients with significant renal dysfunction. The results show that in addition to regional muscle damage generalized myolysis may be detected by scintigraphy with 99mTc-MDP. In cases of regional muscle damage scintigraphy proved to be more sensitive than clinical signs.
D000437:Alcoholism / Q000150:complications; D004164:Diphosphonates; D006012:Glycogen Storage Disease Type V / Q000150:complications; D006801:Humans; D011877:Radionuclide Imaging; D012206:Rhabdomyolysis / Q000000981:diagnostic imaging* / Q000209:etiology; D013667:Technetium; D013669:Technetium Tc 99m Medronate
D004164:Diphosphonates; D013667:Technetium; D013669:Technetium Tc 99m Medronate
Beitrag der Szintigraphie mit 99mTc-Methylendiphosphonat zum Nachweis und zur Lokalisation von Rhabdomyolysen.