[Acute myelogenous leukaemia: prognostic value of infectious complications observed during the induction treatment (author's transl)].
The prognostic value of infectious complications occurring during the induction treatment of acute myelogenous leukaemia is analysed and discussed. Eighty-eight patients were treated with the same chemotherapy. The early major infections (septicemia, pneumonia, ano-rectal abscesses) and on the other hand, the late infections (following the maximum agranulocytosis) are of a bad prognosis. During the second phase of chemotherapy-induced aplasia, the improvement of infection means usually a forthcoming complete remission while its persistence or its aggravation means usually a failure of the chemotherapy. At last, when the complete remission has been achieved, no peculiar feature of the infection is significantly correlated with the survival.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D001853:Bone Marrow / Q000187:drug effects; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy*; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced; D011379:Prognosis; D013997:Time Factors
D000970:Antineoplastic Agents
Leucémies aiguës myéloblastiques: valeur pronostique des complications infectieuses observées lors du traitement d'induction.