[Detection of antigens immunologically related to the envelope antigens of mouse mammary gland cancer virus antigens in human breast cancer tissue].
A highly sensitive method of electroimmunodiffusion in acetate cellulose films developed by G.I. Abelev on the principle of isotachophoresis was used for the detection in human mammary gland carcinoma (HMGC) of an antigen related to envelope antigens of mouse mammary gland cancer (MMGC) virus. In 4 out of 10 HMGC cases, fractions of proteins with molecular weight about 50,000 d previously isolated in PAAG with sodium dodecyl sulphate were found to contain an antigen reacting with the antiserum to p52 MMGCV precipitation band which proved immunological identity of both antigens.
D000230:Adenocarcinoma / Q000276:immunology; D002293:Adenocarcinoma, Scirrhous / Q000276:immunology; D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D001943:Breast Neoplasms / Q000276:immunology*; D002277:Carcinoma / Q000276:immunology; D004589:Electrophoresis, Disc; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D008324:Mammary Tumor Virus, Mouse / Q000032:analysis*; D008875:Middle Aged
D000951:Antigens, Neoplasm; D000956:Antigens, Viral
Vyiavlenie v tkaniakh raka molochnoĭ zhelezy cheloveka antigenov, immunologicheski rodstvennykh obolochechnym antigenam virusa raka molochnoĭ zhelezy mysheĭ.