The presence of nuclear and mitochondrial uracil-DNA glycosylase in extracts of human KB cells.
Extracts of human KB cells contain detectable uracil-DNA glycosylase activity. The majority of the activity is located within the nuclear fraction, however we present evidence for the presence of identifiable uracil-DNA glycosylase activity associated with the mitochondrial fraction of these cells.
D002467:Cell Nucleus / Q000201:enzymology*; D002478:Cells, Cultured; D045647:DNA Glycosylases; D003576:Electron Transport Complex IV / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000201:enzymology*; D009699:N-Glycosyl Hydrolases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D051981:Uracil-DNA Glycosidase
D003576:Electron Transport Complex IV; D045647:DNA Glycosylases; D009699:N-Glycosyl Hydrolases; D051981:Uracil-DNA Glycosidase