[Iatrogenic menopause: a case report (author's transl)].
A 25-year-old woman developed hot flushes due to the artificial menopause induced by cytotoxic chemotherapy (MOPP) during five years for Hodgkin's disease. Plasma FSH levels were found to be greatly elevated while those af 17 beta-oestradiol were markedly diminished. Veralipride was prescribed as one tablet (100 mg) daily for 20 days. Hot flushes disappeared completely, and no recurrence was observed during the 4-month follow-up period after discontinuation of treatment. Tolerance was excellent. This result is in agreement with those of studies reported in the published literature, relating to the treatment of hot flushes and psychofunctional disorders associated with both the natural and artificial menopause.
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D008593:Menopause / Q000187:drug effects; D008594:Menopause, Premature / Q000187:drug effects; D013469:Sulpiride / Q000031:analogs & derivatives / Q000627:therapeutic use
D000970:Antineoplastic Agents; D013469:Sulpiride; C027429:veralipride
A propos d'un cas de ménopause iatrogène.