Diagnosis of malignant tumors on the basis of the current generating capacity of malignant tumorous tissue. I. Examination in vitro, animal experiments and endoscopic measurements.
On the basis of the different electrolyte composition and lactic acid content of malignant tumorous tissue an electrochemical measuring method was worked out for the quick-diagnosis of malignant tumors. The in vitro model experiments and the measurings carried out on mice with Crocker's sarcoma proved the practicability of the electrochemical technique. The present study contains the measuring results of 55 adenocarcinomas and 12 scirrhous carcinomas. The current generating capacity of adenocarcinomas -- both with endoscopic measuring and that performed of samples excised -- exceeds the values measured in the healthy surrounding tissue with 45 to 50%. On the other hand, the generating capacity of scirrhous carcinoma is with 50% lower as the value measured in the healthy tissue. The generating capacity of gastric ulcer and polyp is virtually identical with that of the healthy gastric mucosa. The difference in generating capacity between the healthy tissue and malignant tumorous tissue is statistically significant.
D000230:Adenocarcinoma / Q000175:diagnosis; D002293:Adenocarcinoma, Scirrhous / Q000175:diagnosis; D000818:Animals; D004563:Electrochemistry; D004568:Electrodiagnosis / Q000379:methods*; D004724:Endoscopy; D006801:Humans; D066298:In Vitro Techniques; D007773:Lactates / Q000032:analysis; D051379:Mice; D009369:Neoplasms / Q000032:analysis / Q000175:diagnosis*; D012510:Sarcoma 180 / Q000175:diagnosis
D007773:Lactates