[Effect of a mitogenic concentration on membrane glycoconjugates of human lymphocytes].
Periodate oxidation of human peripheral blood lymphocytes followed by reduction with 3H labelled sodium borohydride and acidic hydrolysis generates N-AN 7, glycerol and propane 1-2 diol. This indicates that sialyl, fucosyl and probably galactosyl residues are oxidized by periodate. Neuraminidase-treated lymphocytes exhibit decreased N-AN 7 levels, increased N-AN 8 levels and increased glycerol levels. Such results were neither found with mouse splenocytes nor with calf lymph node cells.
D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008938:Mitosis / Q000187:drug effects; D010084:Oxidation-Reduction; D010504:Periodic Acid / Q000494:pharmacology*
D010504:Periodic Acid
Action du periodate à concentration mitogène sur les glycoconjugués de membrane de lymphocytes humains.