[Hepatic lesions caused by vinyl chloride monomer in humans. Study of eight clinicopathological cases (author's transl)].
Six hepatic angiosarcomas, one hepatoma and one hepatic "fibrosis" with portal hypertension in patients chronically exposed to vinyl chloride monomer (VCM) are reported. The industrial methods of synthesis and current knowledge concerning the carcinogenic role of VCM are reviewed. Histogenetic and pathogenetic concepts of "fibrosis" and angiosarcomas of liver are exposed.
D000328:Adult; D000818:Animals; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D051381:Rats; D014752:Vinyl Chloride / Q000009:adverse effects*; D014753:Vinyl Compounds / Q000009:adverse effects*
D014753:Vinyl Compounds; D014752:Vinyl Chloride
Pathologie hépatique due au chlorure de vinyle monomère (CVM).