Dose rate dependence of radiation induced IgG membrane receptor alteration [1].
Mouse lymph node lymphocytes are irradiated at different dose rates and the B-cell receptors to anti IgG are tested. The expression of receptors is inhibited by irradiation. It is shown that the effectivity of irradiation increases with decreasing dose rate suggesting that membrane damage may be important for situations of chronic irradiation or implant radiotherapy.
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D007074:Immunoglobulin G / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology* / Q000528:radiation effects; D051379:Mice; D008815:Mice, Inbred Strains; D017452:Receptors, IgG; D011971:Receptors, Immunologic / Q000378:metabolism / Q000528:radiation effects*
D007074:Immunoglobulin G; D017452:Receptors, IgG; D011971:Receptors, Immunologic