Structural requirement for the action of leukotriene B4 on the guinea-pig lung:importance of double bond geometry in the 6, 8, 10-triene unit.
D000818:Animals; D001095:Arachidonic Acids / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D007700:Kinetics; D007975:Leukotriene B4; D008168:Lung / Q000187:drug effects / Q000502:physiology*; D009504:Neutrophils / Q000032:analysis; D009928:Organ Specificity; D011453:Prostaglandins / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship; D013552:Swine; D013931:Thromboxanes / Q000378:metabolism
D001095:Arachidonic Acids; D011453:Prostaglandins; D013931:Thromboxanes; D007975:Leukotriene B4