A mitogenic factor for transformed fibroblasts from human platelets.
Human platelets contain discrete glycoproteins that promote the growth of 3T3 (platelet-derived growth factor 1) and SV3T3 (platelet-derived growth factor 2) cells. The factor that promotes the growth of SV3T3 cells is a heat-labile nondialyzable glycoprotein with an isoelectric point of 7.8 to 8.3.
D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D002455:Cell Division; D002472:Cell Transformation, Viral; D005347:Fibroblasts / Q000166:cytology; D006023:Glycoproteins / Q000097:blood; D006133:Growth Substances / Q000097:blood*; D006801:Humans; D051379:Mice; D008934:Mitogens; D013539:Simian virus 40
D006023:Glycoproteins; D006133:Growth Substances; D008934:Mitogens