title: Effect of ionic environment on the inactivation of poliovirus in water by chlorine.
abstract: The rate of inactivation of poliovirus in water by chlorine is strongly influenced by the pH, which in turn influences the relative amounts of HOCl and OCl- that are present and acting on the virus in the region of pH 6 to 10. The distribution of HOCl and OCl- is influenced to a lesser extent by the addition of NaCl. The major part of the sharp increase in disinfection rate seen with this salt is thought to be due to its effect on the virus itself resulting in an increased chlorine sensitivity, especially at high pH.
mesh_terms: D002713:Chlorine / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D009994:Osmolar Concentration; D017955:Poliovirus / Q000187:drug effects* / Q000254:growth & development; D012965:Sodium Chloride / Q000494:pharmacology; D014871:Water Microbiology
chemical_list: D012965:Sodium Chloride; D002713:Chlorine