Evaluation of chemical disinfectants for aleutian disease virus of mink.
Nine chemicals and commercial disinfectants were tested for inactivation of Aleutian disease virus of mink. In the presence of distilled water, a commercial disinfectant (O-Syl), halogen derivatives (iodophor and sodium hypochlorite), and glutaraldehyde (2.0%) inactivated 4 log10 (based on 0.25 ml) of the virus within 10 minutes at 23 C. Formalin (2.0%) and O-Syl were slower to inactivate the virus, but achieved a 4 log10 reduction in titer by 30 minutes' contact time. In the presence of 10% bovine serum, formalin (1.0%), O-Syl, and sodium hydroxide (0.5%) achieved a 4 log10 reduction within 10 minutes. All agents tested had some virucidal effect.
D000454:Aleutian Mink Disease Virus / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology; D005976:Glutaral / Q000494:pharmacology; D007466:Iodophors / Q000494:pharmacology; D012972:Sodium Hydroxide / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology; D014713:Viruses, Unclassified / Q000187:drug effects*; D014867:Water / Q000494:pharmacology
D004202:Disinfectants; D007466:Iodophors; D014867:Water; D005557:Formaldehyde; D000431:Ethanol; D012972:Sodium Hydroxide; D012973:Sodium Hypochlorite; D002710:Chlorhexidine; D005976:Glutaral