title: [Auxotrophic mutations formed on the incorporation into the E. coli C600 chromosome of transposon Tnl that determines ampicillin resistance].
abstract: Incorporation of transposone Tnl of ampicillin resistance into the chromosome of E. coli C600 resulted in formation of at least 8 types of auxotrophic mutants. The transposone incorporates mainly into the loci the damage of which induces proline deficit (20 per cent). The sites of incorporation of transposone Tnl in the chromosomes of E. coli C600 and E. coli JC411 did not coincide.
mesh_terms: D000667:Ampicillin / Q000037:antagonists & inhibitors*; D002876:Chromosomes, Bacterial / Q000187:drug effects*; D004251:DNA Transposable Elements / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D009154:Mutation; D010403:Penicillin Resistance
chemical_list: D004251:DNA Transposable Elements; D000667:Ampicillin
vernacular_title: Mutatsii auksotrofnosti, voznikaiushchie pri vstraivanii v khromosomu E. coli C600 transpozona Tnl, opredeliaiushchego ustoĭchivost' k ampitsillinu.