Cocaine and amphetamine antagonize the decrease of noradrenergic neurotransmission elicited by oxymetazoline but potentiate the inhibition by alpha-methylnorepinephrine in the perfused cat spleen.
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D003042:Cocaine / Q000494:pharmacology*; D004357:Drug Synergism; D004558:Electric Stimulation; D005260:Female; D007093:Imidazoles / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D008297:Male; D008771:Nordefrin / Q000494:pharmacology*; D009638:Norepinephrine / Q000031:analogs & derivatives* / Q000502:physiology*; D010109:Oxymetazoline / Q000037:antagonists & inhibitors*; D010293:Pargyline / Q000494:pharmacology; D011954:Receptors, Dopamine / Q000187:drug effects; D013154:Spleen / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects*
D007093:Imidazoles; D011954:Receptors, Dopamine; D010109:Oxymetazoline; D010293:Pargyline; D000661:Amphetamine; D003042:Cocaine; D008771:Nordefrin; D009638:Norepinephrine