title: [Combined treatment of rectal cancer].
abstract: In 15 males and 25 females at the age of 24--70 the authors have studied radiation pathomorphosis, the early and late results in anal and low ampullar cancer following preoperative large fractionation irradiation on a gamma-therapeutic machine "Rokus" with the rotation regime of 400--600 rad daily, a total dosage--2000--3000 rad. The operation was performed 2--3 days following the irradiation. Eighteen patients were followed up over 3 years. Recurrences and metastases were noted in 5 cases (glandular-solid and mucosa forms of cancer). A 3-year survival was 72.2% versus 40.7% (P less than 0.001) while using surgical therapy solely.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy; D002288:Adenocarcinoma, Mucinous / Q000473:pathology / Q000628:therapy; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D012007:Rectum / Q000473:pathology / Q000601:surgery
vernacular_title: O kombinirovannom lechenii raka priamoĭ kishki.