Neuropathy associated with chronic low level exposure to n-hexane.
Concentrations of n-hexane greater than the threshold limit value (TLV) of 500 ppm are known to produce peripheral neuropathy. This report describes the case of a worker who developed peripheral neuropathy, with a histologic pattern characteristic of n-hexane toxicity, after chronic on-the-job exposure to n-hexane at concentrations less than 450 ppm. We suggest that the current TLV for n-hexane be reevaluated.
D006586:Hexanes / Q000506:poisoning*; D006801:Humans; D008297:Male; D008452:Maximum Allowable Concentration; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology
D006586:Hexanes; C026385:n-hexane