title: Distribution of antibodies to rotavirus in serum and lacteal secretions of naturally infected swine and their suckling pigs.
abstract: Rotavirus antibodies were demonstrated in lacteal secretions and sera of 20 parturient sows and in sera of their newborn by an enzyme-linked immunosorbent assay blocking technique, using bovine rotavirus cell culture antigen and monospecific antibody to bovine rotavirus. Antibodies to rotavirus occur in the 3 immunoglobulin (Ig) classes IgM, IgA, and IgG in lacteal secretions. High and long-persisting antibody activity was mainly associated with the IgA class. The IgM and IgG decreased to undetectable concentrations in most sows during the 14-day investigation period. Serum antibodies of newborn pigs nursing their dams also decreased rapidly during this time. The heterologous enzyme-linked immunosorbent assay blocking technique was a reliable and rapid procedure for the demonstration of rotavirus antibodies.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D000914:Antibodies, Viral / Q000032:analysis*; D003126:Colostrum / Q000276:immunology; D003967:Diarrhea / Q000276:immunology / Q000662:veterinary; D005260:Female; D007136:Immunoglobulins / Q000032:analysis; D007775:Lactation Disorders / Q000276:immunology / Q000662:veterinary*; D008892:Milk / Q000276:immunology*; D011247:Pregnancy; D012087:Reoviridae / Q000276:immunology*; D012088:Reoviridae Infections / Q000276:immunology / Q000662:veterinary*; D012401:Rotavirus / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007136:Immunoglobulins