Juvenile nasopharyngeal angiofibroma.
The juvenile nasopharyngeal angiofibroma, a locally invasive, non-metastasizing tumour of male adolescence, occurs sporadically throughout the world. Its histiogenesis remains uncertain and its management controversial. These facets of a troublesome and dangerous conditions are discussed and the experiences from handling 9 such tumours seen at Groote Schuur Hospital over a 4-year period (1976-1979) are presented. Surgical excision, using a wide field exposure and pre-operative systemic oestrogen medication, is recommended as the treatment of choice.
D000293:Adolescent; D000328:Adult; D002648:Child; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000628:therapy*