[Immunoenzymatic detection of circulating antitumor antibodies in the rat: development of a quantitative technic and its use in rats bearing grafted colonic tumors].
In order to study the humoral immune response of rats against a colonic tumor, we developed an immuno-enzymatic technique for quantitating specific anti-tumoral antibodies. This technique which uses a monolayer of intact cancer cells as antigen produces objective and reproducible results. Applied to eleven rats carrying grafted colon carcinomas, it allowed the characterization of three different types of evolution of the concentration of circulating antibodies.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000032:analysis*; D003110:Colonic Neoplasms / Q000276:immunology*; D005260:Female; D007124:Immunoenzyme Techniques; D009368:Neoplasm Transplantation; D051381:Rats
D000912:Antibodies, Neoplasm
Détection immunoenzymatique des anticorps antitumoraux circulants chez le rat: mise au point d'une technique quantitative et son application chez des rats porteurs d'une tumeur colique greffée.