title: [Effect of adrenocorticotropin fragments on the memory of Tenebrio molitor beetles].
abstract: Fragments of the adrenocorticotropic hormone ACTH1-24 and ACTH5-7 facilitate memory in the beetle T. molitor, the effect being observed at different stages after learning. An analogue of ACTH5-7 which contains D-phenylalamine, as well as D-phen7-ACTH4-7, inhibit memorization (the results checked 1 day after learning) and induce some other disturbances in the behaviour of beetles. To the 10th day of learning, the effects of the analogues cannot be distinguished from those of L-Phe7-fragments. The results obtained are compared with the known effect of ACTH fragments on memory in vertebrates.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology*; D000818:Animals; D003366:Cosyntropin / Q000494:pharmacology; D008568:Memory / Q000187:drug effects*; D010446:Peptide Fragments / Q000494:pharmacology*; D013712:Tenebrio / Q000502:physiology*; D013997:Time Factors
chemical_list: D010446:Peptide Fragments; D003366:Cosyntropin; D000324:Adrenocorticotropic Hormone
vernacular_title: Vliianie fragmentov adrenokortikotropina na pamiat' zhuka Tenebrio molitor.