Purification of a factor from human blood monocyte-macrophages which stimulates the production of collagenase and prostaglandin E2 by cells cultured from rheumatoid synovial tissues.
D001172:Arthritis, Rheumatoid / Q000378:metabolism*; D002478:Cells, Cultured; D002848:Chromatography, DEAE-Cellulose; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D007375:Interleukin-1; D008264:Macrophages / Q000032:analysis; D003012:Microbial Collagenase / Q000096:biosynthesis*; D009000:Monocytes / Q000032:analysis*; D011458:Prostaglandins E / Q000096:biosynthesis*; D011506:Proteins / Q000302:isolation & purification* / Q000494:pharmacology; D013583:Synovial Membrane / Q000378:metabolism*
D007375:Interleukin-1; D011458:Prostaglandins E; D011506:Proteins; D003012:Microbial Collagenase