Multiple myeloma with bilateral orbital infiltration and polyneuropathy.
Orbital involvement is a rare complication of myeloma usually presenting as unilateral proptosis without pain. A case is reported of a woman with bilateral orbital infiltration without proptosis, who became blind within three months of the onset diplopia. The blindness was due to visual field obstruction, with eyelids covering both corneas; the eyes themselves remained normal. This is the first case of orbital myeloma reported in Australia and only the second case of bilateral primary orbital infiltration with myelomatosis to be reported in the world literature.
D001766:Blindness / Q000209:etiology; D004172:Diplopia / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000150:complications* / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology*