title: Evaluation of chemical disinfectants for aleutian disease virus of mink.
abstract: Nine chemicals and commercial disinfectants were tested for inactivation of Aleutian disease virus of mink. In the presence of distilled water, a commercial disinfectant (O-Syl), halogen derivatives (iodophor and sodium hypochlorite), and glutaraldehyde (2.0%) inactivated 4 log10 (based on 0.25 ml) of the virus within 10 minutes at 23 C. Formalin (2.0%) and O-Syl were slower to inactivate the virus, but achieved a 4 log10 reduction in titer by 30 minutes' contact time. In the presence of 10% bovine serum, formalin (1.0%), O-Syl, and sodium hydroxide (0.5%) achieved a 4 log10 reduction within 10 minutes. All agents tested had some virucidal effect.
mesh_terms: D000454:Aleutian Mink Disease Virus / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology; D005976:Glutaral / Q000494:pharmacology; D007466:Iodophors / Q000494:pharmacology; D012972:Sodium Hydroxide / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology; D014713:Viruses, Unclassified / Q000187:drug effects*; D014867:Water / Q000494:pharmacology
chemical_list: D004202:Disinfectants; D007466:Iodophors; D014867:Water; D005557:Formaldehyde; D000431:Ethanol; D012972:Sodium Hydroxide; D012973:Sodium Hypochlorite; D002710:Chlorhexidine; D005976:Glutaral