Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity.
D000818:Animals; D001095:Arachidonic Acids / Q000032:analysis* / Q000494:pharmacology; D001681:Biological Assay; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D017999:Leukotriene E4; D008168:Lung / Q000187:drug effects / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D013189:SRS-A / Q000032:analysis*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D001095:Arachidonic Acids; D013189:SRS-A; D017999:Leukotriene E4