title: Evaluation of the double immunodiffusion test for the diagnosis of louping ill infection.
abstract: The usefulness of the double immunodiffusion test for the diagnosis of louping ill infection was investigated. Whereas louping ill viral antigen was not detected in brain material from field cases of the infection, its presence was readily confirmed in suckling mouse brain isolates of the virus. The double immunodiffusion test was found to be unreliable as a serological test for the retrospective diagnosis of louping ill infection in the horse.
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology / Q000302:isolation & purification; D006734:Horse Diseases / Q000175:diagnosis* / Q000382:microbiology; D006736:Horses; D005779:Immunodiffusion; D008146:Louping Ill / Q000175:diagnosis* / Q000382:microbiology; D051379:Mice; D012756:Sheep
chemical_list: D000956:Antigens, Viral