title: Hepatocellular carcinoma- etiologic considerations: a review of the literature.
abstract: There are an estimated 120 million hepatitis B virus carriers worldwide. More than 200,000 of these are in the United States. A higher incidence of active hepatitis B virus infection has been observed in patients with hepatocellular carcinoma than in controls, in all geographical regions. This paper reviews the world literature on the relationship of hepatitis B virus to the pathogenesis of hepatocellular carcinoma.
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000209:etiology*; D005060:Europe; D005202:Asia, Eastern; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D009073:Mozambique; D014481:United States