Gynecomastia with ketoconazole.
Three of forty men developed bilateral gynecomastia upon ketoconazole treatment. Symptoms abated despite continued therapy. This appears to be a direct drug effect on breast tissue.
D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000009:adverse effects*; D006177:Gynecomastia / Q000139:chemically induced*; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects*; D007654:Ketoconazole; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000009:adverse effects*
D000935:Antifungal Agents; D007093:Imidazoles; D010879:Piperazines; D007654:Ketoconazole