On the mechanism whereby ACTH and cyclic AMP increase adrenal polyphosphoinositides. Rapid stimulation of the synthesis of phosphatidic acid and derivatives of CDP - diacylglycerol.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology; D003567:Cytidine Diphosphate Diglycerides / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism*; D010712:Phosphatidic Acids / Q000096:biosynthesis*; D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols / Q000096:biosynthesis*; D011108:Polymers / Q000096:biosynthesis; D051381:Rats
D003567:Cytidine Diphosphate Diglycerides; D009702:Nucleoside Diphosphate Sugars; D010712:Phosphatidic Acids; D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols; D011108:Polymers; D000324:Adrenocorticotropic Hormone; D003513:Cycloheximide; D000242:Cyclic AMP