Interaction of H-2Db with mutant histocompatibility gene H (KH-11) in the mouse.
The detectable presence of H (KH-11)b, a mutant non-H-2 histocompatibility gene, was previously shown to depend upon the simultaneous presence, in the skin-graft donor, of both the mutant gene and the H-2b haplotype. The experiments reported here demonstrate that H-2Db is the essential element of H-2b for this interaction. Of two H-2Db histocompatibility mutations, H-2bm13 can replace H-2Db in this interaction, but H-2bm14 cannot.
D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D006183:H-2 Antigens / Q000235:genetics*; D064532:Histocompatibility Antigen H-2D; D007125:Immunogenetics; D008285:Major Histocompatibility Complex; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009154:Mutation
D006183:H-2 Antigens; D064532:Histocompatibility Antigen H-2D