title: Homology and non-homology at the yeast mating type locus.
abstract: Four mutations of the alpha mating type locus of Saccharomyces cerevisiae have been analysed to determine their relationship to the a mating type locus. Mat alpha+ recombinations are produced by mat alpha 2-/MAT but not by mat alpha 1-/MATa diploids. MAT alpha and MATa thus contain regions of homology (coding for at least part of MAT alpha 2) and regions of non-homology (coding for at least part of MAT alpha 1)-the genetic determinant for cell type is larger than the non-homologous sequence seen by DNA-DNA heteroduplexes and genetic analysis. The segment transposed in mating type interconversion includes both types of sequence.
mesh_terms: D001483:Base Sequence; D004251:DNA Transposable Elements; D004271:DNA, Fungal / Q000235:genetics*; D005786:Gene Expression Regulation; D009154:Mutation; D011995:Recombination, Genetic; D012098:Reproduction; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000502:physiology
chemical_list: D004251:DNA Transposable Elements; D004271:DNA, Fungal