Pagetoid lesions associated with carcinoma of the bladder.
Three cases of pagetoid infiltrations by a transitional cell carcinoma are reported. The theories of histogenesis of extramammary Paget's disease are reviewed and discussed. Evidence from these cases suggests that the lesion develops because of the intraepithelial migration of cells.
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000473:pathology / Q000556:secondary*; D010412:Penile Neoplasms / Q000556:secondary; D012878:Skin Neoplasms / Q000556:secondary*; D014523:Urethral Neoplasms / Q000556:secondary; D001749:Urinary Bladder Neoplasms / Q000473:pathology*; D014565:Urogenital Neoplasms / Q000556:secondary*; D014846:Vulvar Neoplasms / Q000556:secondary