[Renal tolerance of combined treatment with cefotaxime and gentamicin (author's transl)].
Treatment of 20 patients with 2 g cefotaxime intravenously and 80 mg gentamicin intramuscularly b.i.d. for various reasons before antibiograms were available showed no recognizable influence on renal function after one week. Patients were without renal disease and of both sexes on groups from 19-23, 36-59 and 63-69 years of age. No damage to the kidneys was evident when creatinine clearance, serum creatinine and urea concentrations and the usual urinalysis were considered.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D002439:Cefotaxime; D002511:Cephalosporins / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D003404:Creatinine / Q000097:blood / Q000652:urine; D005260:Female; D005839:Gentamicins / Q000009:adverse effects*; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000097:blood
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D005839:Gentamicins; D014508:Urea; D003404:Creatinine; D002439:Cefotaxime
Nierenverträglichkeit der kombinierten Behandlung mit Cefotaxim und Gentamicin.