[Researches on the antiaggregative activity of Ginkgo biloba extract (author's transl)].
Sodium lactate applied on the pia-mater of the rabbit induces the appearance of venous platelets thrombi. The same phenomenon occurs in the arteries after electric stimulation of the arterial wall. Gingo biloba extract, i.v. and per os, has been shown capable to partially antagonize these effects, particularly in the venous microcirculation. The ratio between the activity following the two modes of administration is about 1 to 5.
D000818:Animals; D001158:Arteries / Q000187:drug effects; D003864:Depression, Chemical; D007275:Injections, Intravenous; D007441:Intubation, Gastrointestinal; D008297:Male; D010841:Pia Mater / Q000098:blood supply*; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D013300:Streptokinase / Q000494:pharmacology; D013927:Thrombosis / Q000188:drug therapy; D014680:Veins / Q000187:drug effects
D010936:Plant Extracts; D013300:Streptokinase
Recherches sur l'action antiagrégante de l'extrait de Ginko biloba. Activité au niveau des artères et des veines de la pie-mère chez le lapin.