Novel kinetics in the sodium conductance system predicted by the aggregation model of channel gating.
Special voltage-clamp pulse protocols are given that make differential predictions for the kinetics of models based on a simple sequential, simple cyclic, and an aggregation scheme. Detailed kinetic time-courses for the discriminating pulse protocols are numerically derived from the differential equation system that describes the aggregation model.
D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D012964:Sodium / Q000378:metabolism*
D007473:Ion Channels; D012964:Sodium