title: Immunohistochemical characterization of histiocytic tumours.
abstract: Immunohistochemical labelling of histiocytic tumour cells in formalin-fixed paraffin-embedded material was usefully applied to malignant fibrous histiocytoma (MFH) and to malignant histiocytosis (MH). Not all cases of MFH showed a positive reaction, in contrast with the obligatory positive staining in MH. In general, histiocytic tumour cells stained more intensively with alpha 1-antichymotrypsin than with lysozyme. False positive results can be due to intermingled non-neoplastic histiocytes or degenerating neoplastic cells in any mesenchymal tumour.
mesh_terms: D002918:Chymotrypsin / Q000032:analysis / Q000037:antagonists & inhibitors; D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007120:Immunochemistry; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000473:pathology*; D009113:Muramidase / Q000032:analysis; D000514:alpha 1-Antichymotrypsin
chemical_list: D000514:alpha 1-Antichymotrypsin; D009113:Muramidase; D002918:Chymotrypsin