Response of serum prolactin to catechol estrogen in the immature rat.
The response of serum prolactin to the catechol estrogens, 2-hydroxyestrone (2-OH E1) and 2-hydroxyestradiol (2-OH E2) and their primary estrogens, estrone (E1) and estradiol (E2), was studied in 35-day-old male rats. The subcutaneous administration of 50 microgram of 2-OH E1 or 2-OH E2 significantly suppressed serum prolactin concentrations, but they were not significantly altered by the administration of 50 microgram of E1 or E2.
D000818:Animals; D002394:Catechol O-Methyltransferase / Q000378:metabolism; D002396:Catechols / Q000494:pharmacology*; D004958:Estradiol / Q000031:analogs & derivatives / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology*; D002393:Estrogens, Catechol; D006894:Hydroxyestrones / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011388:Prolactin / Q000097:blood*; D051381:Rats
D002396:Catechols; D004967:Estrogens; D002393:Estrogens, Catechol; D006894:Hydroxyestrones; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; C001390:2-hydroxyestradiol; D002394:Catechol O-Methyltransferase; C024980:2-hydroxyestrone