title: Dimethyl sulfoxide inhibits killing of Staphylococcus aureus by polymorphonuclear leukocytes.
abstract: Increasing concentrations of the highly permeable, hydroxyl radical scavenger dimethyl sulfoxide progressively decreased killing of Staphylococcus aureus 502A by human polymorphonuclear leukocytes; methane, a product of the reaction of the hydroxyl radical with dimethyl sulfoxide, was generated in the process.
mesh_terms: D001770:Blood Bactericidal Activity / Q000187:drug effects*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008697:Methane / Q000378:metabolism; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D013211:Staphylococcus aureus / Q000254:growth & development*; D013481:Superoxides / Q000378:metabolism
chemical_list: D013481:Superoxides; D008697:Methane; D004121:Dimethyl Sulfoxide