title: Amebic abscess of the brain.
abstract: Brain abscesses caused by Entamoeba histolytica were treated in two residents of New Jersey, neither of whom had traveled beyond the eastern United States. The diagnosis in Case 1 was confirmed by the presence of ameba in both brain and pituitary abscesses. An elevated indirect hemagglutination (IHA) titer of 1:4096 and response to specific treatment with metronidazole and chloroquin were the criteria for diagnosis in Case 2. The computerized tomographic appearance of an amebic abscess is that of a rapidly progressive lesion without reaction in the adjacent brain. Of the seven reported cures, all of the patients received appropriate chemotherapy. Five of the seven were operated upon.
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000562:Amebiasis / Q000175:diagnosis*; D001922:Brain Abscess / Q000175:diagnosis*; D004748:Entamoeba histolytica / Q000302:isolation & purification; D004749:Entamoebiasis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000000981:diagnostic imaging; D010900:Pituitary Diseases / Q000175:diagnosis*; D010902:Pituitary Gland / Q000469:parasitology / Q000473:pathology; D013702:Temporal Lobe / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed