title: Physical exercise stimulates marked concomitant release of beta-endorphin and adrenocorticotropic hormone (ACTH) in peripheral blood in man.
abstract: ACTH and beta-endorphin have been evaluated by means of a specific and sensitive radioimmunoassay in athletes reaching a status of physical stress. A concomitant marked increase of these 2 peptides has been recorded. The implications of this finding lead to the conclusion that stress stimulates the synthesis of the common precursor (31 K) in the pituitary.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D004723:Endorphins / Q000097:blood*; D006801:Humans; D008297:Male; D009619:Nociceptors / Q000502:physiology; D005082:Physical Exertion; D011863:Radioimmunoassay
chemical_list: D004723:Endorphins; D000324:Adrenocorticotropic Hormone