Beta-adrenergic receptors of human polymorphonuclear leukocytes.
125I-iodohydroxybenzylpindolol (IHYP) is a beta-adrenergic antagonist used as a ligand for the characterization of beta-adrenergic receptors in various cell preparations. Since IHYP may be adsorbed to surfaces such as test tubes and pipet tips, it is necessary to measure the actual free concentration of IHYP in the incubation solution. With this modification, the number of beta-adrenergic receptors in human peripheral PMNs can be determined with greater precision.
D006801:Humans; D009504:Neutrophils / Q000032:analysis*; D010869:Pindolol / Q000031:analogs & derivatives / Q000378:metabolism; D011869:Radioligand Assay / Q000379:methods*; D011941:Receptors, Adrenergic / Q000032:analysis*; D011943:Receptors, Adrenergic, beta / Q000032:analysis* / Q000378:metabolism
D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; C011878:iodohydroxybenzylpindolol; D010869:Pindolol