Diagnostic importance of immunological markers in lymphoma involving the central nervous system.
In an elderly woman, lymphoma involved the central nervous system and unusual nonlymphoreticular sites. Cerebrospinal fluid cell surface marker studies revealed a clone of malignant B cells. Studies of peripheral blood demonstrated a systemic disturbance of immune regulation similar to Epstein-Barr virus infections and the acquired immunodeficiency syndrome.
D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D001402:B-Lymphocytes; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000276:immunology; D002555:Cerebrospinal Fluid / Q000166:cytology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008223:Lymphoma / Q000175:diagnosis* / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000502:physiology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D007136:Immunoglobulins