Antidiuretic hormone immunoactivity in tumour tissue from patients with bronchogenic carcinoma: with and without hyponatraemia.
Antidiuretic hormone (ADH) immunoactivity (28--164 pg/mg wet weight) was detected in the tumour tissue of only three out of thirty-two patients with carcinoma of the bronchus. All three patients had small oat-cell tumours and two had persistent hyponatraemia prior to death. Serum sodium was not obtained in the third patient. Serum sodium was normal in the remaining twenty-nine patients with undetectable ADH immunoactivity.
D000230:Adenocarcinoma / Q000378:metabolism; D000368:Aged; D018288:Carcinoma, Small Cell / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000150:complications*; D008175:Lung Neoplasms / Q000150:complications / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D014667:Vasopressins / Q000378:metabolism*
D014667:Vasopressins