title: Heberden oration 1979: human aberrations of purine metabolism and their significance for rheumatology.
mesh_terms: D000243:Adenosine Deaminase / Q000172:deficiency; D000328:Adult; D002648:Child; D005260:Female; D006073:Gout / Q000145:classification / Q000201:enzymology; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency; D007153:Immunologic Deficiency Syndromes / Q000201:enzymology; D007926:Lesch-Nyhan Syndrome / Q000175:diagnosis / Q000209:etiology; D008297:Male; D011247:Pregnancy; D011683:Purine-Nucleoside Phosphorylase / Q000172:deficiency; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000201:enzymology*; D011687:Purines / Q000378:metabolism; D012216:Rheumatic Diseases / Q000201:enzymology* / Q000235:genetics; D012268:Ribose-Phosphate Pyrophosphokinase / Q000378:metabolism; D013601:T-Lymphocytes / Q000201:enzymology; D014527:Uric Acid / Q000652:urine
chemical_list: D011687:Purines; D014527:Uric Acid; D011683:Purine-Nucleoside Phosphorylase; D007041:Hypoxanthine Phosphoribosyltransferase; D012268:Ribose-Phosphate Pyrophosphokinase; D000243:Adenosine Deaminase