An endogenous substance from porcine brain antagonizes the anticonvulsant effect of diazepam.
D000818:Animals; D000927:Anticonvulsants; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D003975:Diazepam / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000302:isolation & purification / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000378:metabolism; D011963:Receptors, GABA-A; D011957:Receptors, Opioid / Q000378:metabolism*; D012640:Seizures / Q000503:physiopathology; D013552:Swine; D013570:Synaptic Membranes / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D000927:Anticonvulsants; D009419:Nerve Tissue Proteins; D011956:Receptors, Cell Surface; D011963:Receptors, GABA-A; D011957:Receptors, Opioid; D005680:gamma-Aminobutyric Acid; D003975:Diazepam