title: Accumulation of Tx-99m phosphonate complexes in metastatic lesions from colon and lung carcinomas.
abstract: Cases are presented in which Tc-99m methylene diphosphonate accumulated in a lung metastasis from well differentiated adenocarcinoma of the colon, and in a hepatic metastasis from oat cell carcinoma of the lung. To our knowledge, this is the first report of Tc-99m phosphonate complexes concentrated in a pulmonary metastasis of colonic caecinoma or in a hepatic metastasis of oat cell lung carcinoma. The exact mechanism for this non-osseous uptake of bone scanning agents is still unknown.
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary; D000368:Aged; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging / Q000556:secondary; D003102:Colloids; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D004164:Diphosphonates; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013455:Sulfur; D013667:Technetium
chemical_list: D003102:Colloids; D004164:Diphosphonates; D013455:Sulfur; D013667:Technetium