title: Enterotoxaemia involving Clostridium perfringens iota toxin in a hysterectomy-derived rabbit colony.
abstract: During an explosive outbreak of fatal enteropathic disease involving Clostridium perfringens iota (i) toxin, a total of 183 deaths occurred in 18 weeks. The clinical signs and post-mortem findings are reported. Examinations for virus, Bacillus piliformis and coccidia were negative. Clostridium perfringens i toxin was detected in 22 of 27 animals examined (81.5%), but clostridia were not isolated. Various treatments were attempted. It is concluded that i toxin and the syndrome described are closely related.
mesh_terms: D000818:Animals; D002432:Cecum / Q000473:pathology; D003015:Clostridium Infections / Q000662:veterinary*; D003016:Clostridium perfringens; D004767:Enterotoxemia / Q000209:etiology* / Q000473:pathology; D004768:Enterotoxins / Q000032:analysis; D005856:Germ-Free Life; D007044:Hysterectomy / Q000662:veterinary; D007668:Kidney / Q000473:pathology; D011817:Rabbits
chemical_list: D004768:Enterotoxins