[Interest of clinical classification in prognosis and therapeutics of multiform glioblastomas of adult patients (author's transl)].
Since 1978 we studied the different clinical prognostic factors on the survival of patients with malignant gliomas. The two main clinical factors of survival incidence are age and post-operative neurological status, or after anti-oedema treatment. We have established a clinical classification ; Group I : patients under 50 years with a good neurological status. Group II : Patients with one pejorative factor : age superior to 50 years, or poor neurological status. Group III : patients with two pejorative factors : age superior to 50 years and poor neurological status, or patients above 65 years. Our results confirm such an approach, by the study of 96 patients under a similar treatment. Histological grade may introduce a bias in such a study ; we have therefore studied the 55 patients whose multiform glioblastoma had an histological confirmation. This second analysis confirms the validity of our study, which is then the basis of the therapeutic approach to each group of patients.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D005909:Glioblastoma / Q000145:classification* / Q000401:mortality / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011379:Prognosis
Intérêt d'une classification clinique dans le pronostic et la stratégie thérapeutique des glioblastomes multiformes de l'adulte. A propos de cinquante-cinq cas.