Nuclear magnetic resonance at low temperatures in lyophilized and non lyophilized normal and tumoral tissues. III. Study of the solid--fluid interface.
Adsorption water on lyophilized and non-lyophilized, normal and malignant tumoral tissues was studied by nuclear magnetic resonance. Comparative study of variations in the proton signal amplitude (A) and the water proton line width (delta v) at temperatures within the 0 degree to --40 degrees C range showed: (a) The identical behaviour of the proton signal amplitude of water adsorbed on normal rat tissues (liver, skeletal muscle). (b) Similar behaviour of the amplitude in malignant tumoral tissues and hepatic embryonic tissue. (c) Dependence of the relative variation of the resonance line width at --25 degrees and --5 degrees C upon hydration of the sample suggested that there was no difference between malignant and normal tissues at the level of the macromolecular structure-adsorption water interface.
D000818:Animals; D005612:Freeze Drying; D008099:Liver / Q000032:analysis* / Q000196:embryology; D009682:Magnetic Resonance Spectroscopy; D009132:Muscles / Q000032:analysis*; D009374:Neoplasms, Experimental / Q000032:analysis*; D011522:Protons; D051381:Rats; D012513:Sarcoma, Experimental / Q000032:analysis; D013696:Temperature; D014867:Water
D011522:Protons; D014867:Water