title: A murine stage-specific embryonic antigen (SSEA-2) is expressed on some murine SV40-transformed cells.
abstract: A stage-specific embryonic antigen-2 (SSEA-2) found on murine preimplantation embryos is maximally expressed on 4- to 8-cell stage embryos and is present in decreasing amounts of morulae and blastocysts. This antigenic determinant is also expressed on murine teratocarcinoma cells, sperm, and some, but not all, SV40-transformed mouse cell lines. Analysis of solubilized immunoprecipitates by SDS-gel electrophoresis indicates that this cell surface molecule is not the 54,000 m.w. protein shared by teratocarcinoma and SV40-transformed cell lines.
mesh_terms: D000042:Absorption; D000818:Animals; D001755:Blastocyst / Q000276:immunology; D002460:Cell Line; D002472:Cell Transformation, Viral; D011232:Chemical Precipitation; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D007106:Immune Sera / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D011817:Rabbits; D013539:Simian virus 40 / Q000276:immunology*; D013724:Teratoma / Q000276:immunology
chemical_list: D007106:Immune Sera