title: [Light-microscopic study of classified virus warts (HPV-1 and HPV-4) (author's transl)].
abstract: Histological investigations of verrucae vulgares of the hand and of plantar warts show striking differences between HPV-1-induced warts and those caused by the virus type HPV-4. In warts caused by HPV-1 massive vacuolization and disturbance of epidermal cell differentiation through the entire thickness of the epidermis is predominant whereas in HPV-4 stimulated warts cell differentiation is impaired to a much lesser degree. Despite the presence of inclusions and of vacuolized cells a thick stratum granulosum and a compact horny layer are formed in the latter type.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000648:ultrastructure; D012867:Skin / Q000473:pathology; D014412:Tumor Virus Infections / Q000382:microbiology* / Q000473:pathology; D014617:Vacuoles / Q000648:ultrastructure; D014860:Warts / Q000382:microbiology* / Q000473:pathology
vernacular_title: Lichtmikroskopische Untersuchungen an typisierten Viruswarzen (HPV-1 und HPV-4).