title: Acid and alkaline phosphatase in macrophages of Tenebrio molitor larvae stimulated with asbestos.
abstract: The authors studied the activity of acid and alkaline phosphatase in macrophages of Tenebrio molitor larvae stimulated with various types of asbestos: A and B chrysotile, crocidolite, amosite and anthophylite. The activity of the two enzymes increased, as did those of beta-galactosidase and N-acetyl-beta-D-glucosaminidase, two previously assayed enzymes. The increase indicates the toxic action of various types of asbestos and correlates to variations in the mortality curves. The increases of the enzymatic activity and the macrophage response vary with the type of asbestos.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D001194:Asbestos / Q000494:pharmacology*; D017636:Asbestos, Amphibole; D017638:Asbestos, Crocidolite; D017632:Asbestos, Serpentine; D003593:Cytoplasm / Q000201:enzymology; D006458:Hemolymph / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology; D008264:Macrophages / Q000201:enzymology*; D013712:Tenebrio / Q000201:enzymology; D013997:Time Factors
chemical_list: D017636:Asbestos, Amphibole; D017632:Asbestos, Serpentine; D017638:Asbestos, Crocidolite; D001194:Asbestos; C025965:anthophyllite; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase