Antibody to hepatitis A virus in plasma of Danish blood donors and in immune serum globulin produced in Denmark.
Antibody to hepatitis A virus (anti-HAV) was studied in 225 Danish blood donors. The prevalence was found to be 3% in individuals younger than 30 years but then rising with age to 78% in individuals older than 55 years. The titer of anti-HAV in 51 lots of Danish immune serum globulin (ISG) produced from June 1969 to June 1977 was found to vary between 2300 and 5900 except for 2 with titers of 14000 and 28000. The titers did not change during the period and compared well to 3 lots of ISG produced in the USA and selected by the manufacturer because of a high anti-HAV titer.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D001782:Blood Donors; D003718:Denmark; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012712:Serum Globulins / Q000032:analysis*
D000914:Antibodies, Viral; D012712:Serum Globulins