[Role of alpha- and beta-adrenoreceptors in isolated guinea pig trachea anaphylaxis to aerosol tick (D. pteronyssinus) allergy].
Experiments were performed on inhalation-sensitized guinea-pigs, with the use of immunoallergic neurohistochemical techniques. Anaphylactic tracheobronchial spasm was shown to be related not only to the degree of sensitization but also to the state of alpha- and beta-adrenoreceptors. Sensitization, in its turn, changed the function of adrenoreceptors. It increased histamine sensitivity and decreased catecholamine sensitivity of an isolated organ.
D000336:Aerosols; D000485:Allergens; D000707:Anaphylaxis / Q000276:immunology*; D000818:Animals; D001986:Bronchial Spasm / Q000503:physiopathology*; D004087:Dihydroergotamine; D004391:Dust; D006168:Guinea Pigs; D009130:Muscle, Smooth / Q000503:physiopathology; D011433:Propranolol; D011941:Receptors, Adrenergic / Q000502:physiology*; D011942:Receptors, Adrenergic, alpha / Q000502:physiology*; D011943:Receptors, Adrenergic, beta / Q000502:physiology*; D013987:Ticks / Q000276:immunology*; D014132:Trachea / Q000276:immunology*
D000336:Aerosols; D000485:Allergens; D004391:Dust; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D004087:Dihydroergotamine; D011433:Propranolol
Rol' alpha- i beta-adrenoretseptorov v anafilaksii izolirovannoĭ trakheĭ morskikh svinok pri aérozol'noĭ kleshchevoĭ (D. pteronyssinus) allergii.