title: [Radiological signs of a disease that is dying out: hepato-splenic atrophy and cholangiocarcinoma after administration of thorium dioxide (Thorotrast)].
abstract: The cases of two patients with radio-opaque residues of contrast medium (Thorotrast) in the abdomen, at the level of the liver, the spleen and certain lymph node groups of the hepatic hilum and the pancreas are reported. In one of the two patients (both of whom had undergone examination with this contrast medium in the '40s) necropsy showed the existence of cholangiocarcinoma. It is therefore considered useful to recall the X-ray signs typical of this pathology, which is dying out after the abandonment of thorium dioxide as an X-ray contrast medium.
mesh_terms: D002759:Adenoma, Bile Duct / Q000139:chemically induced*; D000368:Aged; D000792:Angiography / Q000009:adverse effects; D001284:Atrophy; D001650:Bile Duct Neoplasms / Q000139:chemically induced*; D056486:Chemical and Drug Induced Liver Injury; D003287:Contrast Media / Q000009:adverse effects; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D010190:Pancreatic Neoplasms / Q000556:secondary; D013158:Splenic Diseases / Q000139:chemically induced*; D013911:Thorium Dioxide / Q000009:adverse effects*; D014567:Urography / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D013911:Thorium Dioxide
vernacular_title: Segni radiologici di una patologia in via di estinzione: atrofia-epato-splenica e colangiocarcinoma dopo somministrazione di diossido di torio (Thorotrast).