[Alcohol-induced Cushing's syndrome: case report (author's transl)].
Reversible Cushing's syndrome with typical physical appearance and increased basal plasma-cortisol level developed in a 48-year-old man with essential arterial hypertension, as a result of chronic alcohol abuse and could not be supressed by prolonged dexamethason inhibition. Alcohol abstinence within a few weeks produced remission with normal adrenocortical function and regulation without any other therapeutic measures. Renewed alcohol consumption quickly brought about again the alcohol-induced Cushing's syndrome. An abnormality of central regulation with inadequate ACTH secretion was the cause of the hypercortisolism. Previously reported cases of alcohol-induced Cushing's syndrome are not uniform: in some the diagnosis is in doubt.
D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000437:Alcoholism / Q000150:complications*; D003480:Cushing Syndrome / Q000097:blood / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Das alkoholinduzierte Cushing-Syndrom.