A serological study of herpes simplex virus type 1 antibody over a 13-year period.
HSV-1 serum antibody titers determined by 50% plaque reduction and confirmed by radioimmunoassay in 11 samples from an individual over a 13-year period indicated a significant increase between the first sample and a sample taken 9 years later. This increase did not seem to reflect loss of antibody in the low titered serum sample due to storage.
D000914:Antibodies, Viral / Q000032:analysis*; D002478:Cells, Cultured; D004926:Escherichia coli / Q000276:immunology; D006801:Humans; D011863:Radioimmunoassay; D012698:Serologic Tests; D018139:Simplexvirus / Q000276:immunology*; D013048:Specimen Handling; D013997:Time Factors
D000914:Antibodies, Viral