title: [Changes in the serum acid phosphatase activity of guinea pigs poisoned with C1 perfringens type A toxin and a mixture of toxin and a broth culture filtrate].
abstract: It was shown in experiments on guinea pigs that the injection of C1. perfringens type A toxoid induced an increase in acid phosphatase activity of animal blood serum. The action of the toxoid increased under the effect of C1. butyricum cultural filtrate, which gave rise to an earlier enhancement of the specific activity of the enzyme as compared to the injection of the toxoid alone. Increased activity of acid phosphatase may play a pathogenetic role in cases of anaerobic infection caused by association of C1. perfringens and C1. butyricum.
mesh_terms: D000135:Acid Phosphatase / Q000097:blood*; D000818:Animals; D001427:Bacterial Toxins / Q000302:isolation & purification / Q000506:poisoning*; D003013:Clostridium / Q000032:analysis; D003016:Clostridium perfringens / Q000032:analysis; D006168:Guinea Pigs
chemical_list: D001427:Bacterial Toxins; D000135:Acid Phosphatase
vernacular_title: Izmeneniia aktivnosti kisloĭ fosfatazy syvorotki krovi morskikh svinok pri intoksikatsii, vyzvannoĭ toksinom C1. perfringens tipa A i smes'iu toksina s fil'tratom bul'onnoĭ kul'tury.