title: [Clinical trial of sodium levothyroxine in the treatment of hypothyroidism in adults (author's transl)].
abstract: The authors present the results of a clinical trial performed on 44 patients with hypothyroidism. All were treated with L-thyroxine (L-T4) during 6 months. In 39 patients out of the 44 in this trial, clinical and hormonal balance was achieved. Tolerance was excellent and no clinical evidence of overdosage was observed, comprising the 11 patients whose plasma T4 values were slightly exceeding normal values. The optimal substitution dosage most commonly applied, was on the average of 150 micrograms daily. The authors testify their interest in the L-thyroxine (L-T4) because it is the physiological natural hormone, used with a precise dosage. It is the first L-T4 launched in France.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012964:Sodium; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000008:administration & dosage* / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D012964:Sodium; D013974:Thyroxine
vernacular_title: Essai clinique de la lévothyroxine sodique (L-T4) dans le traitement de l'hypothyroïdie de l'adulte.