title: Mammalian gonadal determination and gametogenesis.
abstract: Although a relationship between the X and Y chromosomes and mammalian sexual development has long been recognized, a detailed understanding of this relation is still lacking. Recent advances in somatic cell genetics and recombinant DNA technology should provide the tools for solving this fundamental problem in developmental genetics.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification; D004262:DNA Restriction Enzymes; D012734:Disorders of Sex Development; D005260:Female; D005298:Fertility; D005819:Genetic Markers; D006182:H-Y Antigen / Q000235:genetics; D008297:Male; D008322:Mammals / Q000235:genetics*; D051379:Mice; D009693:Nucleic Acid Hybridization; D009866:Oogenesis; D010053:Ovary / Q000196:embryology; D012730:Sex Chromosomes; D012732:Sex Determination Analysis; D012733:Sex Differentiation; D013091:Spermatogenesis; D013737:Testis / Q000196:embryology
chemical_list: D005819:Genetic Markers; D006182:H-Y Antigen; D004247:DNA; D004262:DNA Restriction Enzymes