Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism; D000818:Animals; D002262:Carboxy-Lyases / Q000096:biosynthesis*; D016861:Cyclooxygenase Inhibitors; D005260:Female; D007213:Indomethacin / Q000494:pharmacology; D051379:Mice; D009374:Neoplasms, Experimental / Q000517:prevention & control; D009955:Ornithine Decarboxylase / Q000096:biosynthesis*; D010704:Phorbols / Q000037:antagonists & inhibitors*; D011453:Prostaglandins / Q000378:metabolism*; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012878:Skin Neoplasms / Q000517:prevention & control*; D013755:Tetradecanoylphorbol Acetate / Q000037:antagonists & inhibitors*; D014212:Tretinoin / Q000037:antagonists & inhibitors
D016861:Cyclooxygenase Inhibitors; D010704:Phorbols; D011453:Prostaglandins; D011459:Prostaglandins E, Synthetic; D014212:Tretinoin; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase; D013755:Tetradecanoylphorbol Acetate; D007213:Indomethacin