Peripheral neuropathy associated with disulfiram administration.
Very few cases of peripheral neuropathy as a complication of disulfiram therapy have been described. The clinical and electrodiagnostic features of two patients who developed a severe peripheral neuropathy during disulfiram administration are reported. Evidence is presented which suggests that disulfiram causes a dying-back axonal neuropathy.
D000200:Action Potentials; D000328:Adult; D000437:Alcoholism / Q000175:diagnosis; D003937:Diagnosis, Differential; D004221:Disulfiram / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D009431:Neural Conduction; D010525:Peripheral Nerves / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology
D004221:Disulfiram