title: [Comparison of 2 inactivated vaccines against Aujeszky's disease in pigs].
abstract: Equal efficiency was proved by comparing two inactivated vaccines against Aujeszky's disease (AD) virus manufactured in Czechoslovakia. Fifteen porkers at the age of four weeks were included in the experiment, not possessing any specific antibodies to AD virus. Each vaccine was inoculated intramuscularly to five porkers (2 ml) in the interval of three weeks. The third group of five porkers was control. The samples of blood serum were subjected to the serum neutralizing test and radioimmunoassay (RIA) 21 and 35 days after vaccination. Three weeks after vaccination, antibody titers were demonstrated in nine from ten vaccinated porkers by RIA, in one pig by SNT. All 15 porkers were challenged with live virulent strain of the virus on the 35th day after the start of the experiment. The ten vaccinated porkers survived the infection after a short feverish disorder. Out of the five unvaccinated controls four pigs died; the patho-anatomic findings demonstrated necrotic tonsillitis and lobar bronchopneumonia. The finding in the fifth control porker was identical; the porker was killed 15 days after infection.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D011557:Pseudorabies / Q000517:prevention & control*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Srovnání dvou inaktivovaných vakcín proti Aujeszkyho chorobĕ u prasat.