Glioblastoma multiforme with tuberous sclerosis. Report of a case.
Gliomas of the CNS associated with tuberous sclerosis have been well documented; malignant degeneration to glioblastoma multiforme, however, is rare. We studied a 17-year-old boy with stigmata of tuberous sclerosis and a cerebral glioblastoma multiforme. The rarity of this occurrence suggests that neoplasms arising from hamartomas may behave differently than those CNS tumors that arise apparently de novo.
D000293:Adolescent; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D002540:Cerebral Cortex; D005909:Glioblastoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009778:Occipital Lobe / Q000473:pathology; D014402:Tuberous Sclerosis / Q000150:complications*