title: Malignant acanthosis nigricans: a review.
abstract: Malignant acanthosis nigricans is a dermatosis that appears grossly as a hyperpigmented, velvety, or verrucous hyperplasia of the epidermis, most marked in flexural areas. It is always associated with a malignancy. In 277 cases reviewed, the condition was associated with gastric carcinomas in 55.5%, with other intra-abdominal carcinomas in 17.7%, and with malignancies in other sites in 26.8%. Current theories for the association and pathogenesis of the cutaneous process are discussed.
mesh_terms: D000008:Abdominal Neoplasms / Q000150:complications*; D000052:Acanthosis Nigricans / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D000230:Adenocarcinoma / Q000150:complications; D000328:Adult; D002277:Carcinoma / Q000150:complications; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000150:complications*; D010051:Ovarian Neoplasms / Q000150:complications; D013274:Stomach Neoplasms / Q000150:complications*; D013798:Thecoma / Q000150:complications