title: [Long-term changes in the immune system following cytostatic polychemotherapy in patients with testicular tumors in remission].
abstract: Patients who received combination chemotherapy for metastatic nonseminomatous testicular cancer showed a decreased Con A induced suppressor cell function. Additionally 15% of the patients who received ifosfamid had a decreased IgM-serum concentration, an increased number of macrophages and a decreased proliferation rate in MLC.
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007069:Ifosfamide / Q000494:pharmacology; D007107:Immune System / Q000187:drug effects*; D007136:Immunoglobulins / Q000378:metabolism; D008213:Lymphocyte Activation / Q000187:drug effects; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000145:classification / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000276:immunology*
chemical_list: D007136:Immunoglobulins; D007069:Ifosfamide
vernacular_title: Langzeitveränderungen des Immunsystems nach zytostatischer Polychemotherapie bei Patienten mit Hodentumoren in Remission.