title: [Metformin induced lactic acidosis. Two new cases (author's transl)].
abstract: Two cases of severe lactic acidosis, following a metformin treatment are presented. A continued treatment in spite of the occurrence of renal failure, was responsible for this lactic acidosis. Indeed the metformin elimination is assured by kidney in 80%. Renal function must be evaluated before and during metformin treatment. Treatment must be stopped when any trouble of renal function appeared.
mesh_terms: D000138:Acidosis / Q000097:blood / Q000139:chemically induced*; D000368:Aged; D005260:Female; D006801:Humans; D007773:Lactates / Q000097:blood*; D008297:Male; D008687:Metformin / Q000009:adverse effects*
chemical_list: D007773:Lactates; D008687:Metformin
vernacular_title: Acidose lactique à la metformine. Deux nouveaux cas.