[Embryogenesis and early postnatal development of rats following transplacental sex hormone administration].
A study was made of the effect of different doses of testosterone propionate, sinestrol, diethylstilbestrol and sigetin administered to rats during the last three days of pregnancy on the embryogenesis and postnatal development of the progeny. It was established that sex hormones (except sigetin) often disturb pregnancy, labor and lactation. They also exert a musculinizing and sterilizing effect on the progeny. Sigetin produces no action on embryogenesis or postnatal development of rats.
D000818:Animals; D000831:Animals, Newborn; D001835:Body Weight; D004054:Diethylstilbestrol / Q000633:toxicity*; D012734:Disorders of Sex Development / Q000139:chemically induced; D004622:Embryo, Mammalian / Q000187:drug effects; D004967:Estrogens / Q000633:toxicity*; D004971:Estrus; D005260:Female; D005836:Genitalia, Female / Q000196:embryology; D005837:Genitalia, Male / Q000196:embryology; D006589:Hexestrol / Q000633:toxicity*; D007775:Lactation Disorders / Q000139:chemically induced; D008297:Male; D008431:Maternal-Fetal Exchange; D007744:Obstetric Labor Complications / Q000139:chemically induced; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced; D051381:Rats; D013739:Testosterone / Q000633:toxicity*
D004967:Estrogens; D006589:Hexestrol; D013739:Testosterone; D004054:Diethylstilbestrol
Embriogenez i rannee postnatal'noe razvitie krys pri transplatsentarnom vvedenii polovykh gormonov.