Liver pyridoxal kinase-interaction with metal ions.
The binding of some mono- and divalent cations to liver pyridoxal kinase induces spectral changes. These changes in the UV absorption spectrum are consistent with our reported specificities of essential activation with K+ and NH+4 ions and low concentration of Zn2+ and much higher concentration of Mn2+.
D000643:Ammonium Chloride / Q000378:metabolism; D000818:Animals; D002412:Cations / Q000378:metabolism*; D002712:Chlorides; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008274:Magnesium / Q000378:metabolism; D015636:Magnesium Chloride; D008345:Manganese / Q000378:metabolism; D017895:Manganese Compounds; D010770:Phosphotransferases / Q000378:metabolism*; D011189:Potassium Chloride / Q000378:metabolism; D011731:Pyridoxal Kinase / Q000378:metabolism*; D011736:Pyridoxine / Q000378:metabolism; D012756:Sheep; D012965:Sodium Chloride / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D013431:Sulfates / Q000378:metabolism; D015032:Zinc / Q000378:metabolism; D019287:Zinc Sulfate
D002412:Cations; D002712:Chlorides; D017895:Manganese Compounds; D013431:Sulfates; D000643:Ammonium Chloride; D015636:Magnesium Chloride; D008345:Manganese; D012965:Sodium Chloride; D011189:Potassium Chloride; D019287:Zinc Sulfate; D010770:Phosphotransferases; D011731:Pyridoxal Kinase; D008274:Magnesium; D015032:Zinc; D011736:Pyridoxine; C025340:manganese chloride