[Concentration of free and esterified cholecalciferol in the tissues of rats with hypervitaminosis D].
Within 4 hrs after intravenous administration into rats of cholecalciferol maximal concentration of the compound, which was increased depending on the dose used, was found in liver tissue, within 24 hrs--in kidney. Increase in cholecalciferol doses led to an increase in the ratio of the esterified compound to its free form. Content of the esterified cholecalciferol reached the highest level in kidney within 4 hrs and 24 hrs after administration of all the doses of cholecalciferol studied.
D000818:Animals; D001842:Bone and Bones / Q000032:analysis; D002762:Cholecalciferol / Q000032:analysis / Q000378:metabolism / Q000506:poisoning*; D004951:Esterification; D004952:Esters; D005260:Female; D007421:Intestine, Small / Q000032:analysis; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D009132:Muscles / Q000032:analysis; D051381:Rats
D004952:Esters; D002762:Cholecalciferol
Soderzhanie svobodnogo i eterifitsirovannogo kholekal'tsiferola v tkaniakh krys pri D-vitaminnoi intoksikatsii.