An epidemic of Getah virus infection among racehorses: properties of the virus.
A virus (Sakai) which had been recovered from an outbreak of disease in horses was found to be a small spherical enveloped RNA virus with a diameter of approximately 70 nm and a buoyant density of 1.22 g per ml. It grew well and produced a cytopathic effect in a variety of cell cultures; it was sensitive to organic solvents, heat and low pH. It agglutinated goose erythrocytes in a 0.35 M sodium chloride solution at an optimum pH of 6.2 and was antigenically identical or closely related to Getah virus, a member of the alphavirus subgroup of the Togaviridae.
D000524:Alphavirus / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D003168:Complement Fixation Tests; D006734:Horse Diseases / Q000453:epidemiology / Q000382:microbiology*; D006736:Horses; D007564:Japan; D009500:Neutralization Tests; D014036:Togaviridae Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*
D000956:Antigens, Viral