Interaction of concanavalin A with herpes simplex virus infected cells.
Incubation of herpes simplex virus (HSV) infected cells with concanavalin A (Con A) interferes with binding of the Fc portion of antibody. In addition, the lectin inhibits complement mediated cytolysis, probably by interference with antibody binding. These results suggest that binding sites of both Fc and HSV antibody contain residues which attract Con A.
D000818:Animals; D000914:Antibodies, Viral; D001666:Binding Sites, Antibody; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D003208:Concanavalin A / Q000494:pharmacology; D000882:Haplorhini; D007668:Kidney; D011961:Receptors, Fc / Q000032:analysis*; D018139:Simplexvirus / Q000254:growth & development* / Q000276:immunology
D000914:Antibodies, Viral; D011961:Receptors, Fc; D003208:Concanavalin A