Aorticopulmonary paraganglioma and gastric leiomyoblastoma in a young woman.
The 16th report of a patient with "Carney's triad" is presented. The triad consists of an extra-adrenal paraganglioma, gastric leiomyoblastomas and a pulmonary chondroma. The diagnosis is made by discovery of the presence of at least two of these individually rare tumors. The patient described as 15 year old girl who presented with a pericardial effusion caused by an invasive mediastinal paraganglioma. She was subsequently found to have multiple gastric leiomyoblastomas. The leiomyoblastomas have been resected. The paraganglioma was unresectable, and the patient underwent sequential radiation therapy and chemotherapy without response. Concomitant 5-fluorouracil chemotherapy with radiation resulted in an objective regression of tumor mass.
D000293:Adolescent; D002812:Chondroma / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis*; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010236:Paraganglioma, Extra-Adrenal / Q000175:diagnosis*; D010490:Pericardial Effusion / Q000209:etiology; D013274:Stomach Neoplasms / Q000175:diagnosis*