The use of vesicular stomatitis (visna virus) pseudotypes to demonstrate visna virus receptors in cells from different species.
Superinfection of visna virus (VV)-infected cells with vesicular stomatitis virus (VSV) resulted in the formation of a pseudotype virus population containing a VSV genome within a VV coat [designated VSV (VV)] as determined by plaque reduction neutralization with antisera to VSV and VV. These VSV (VV) virions were capable of infecting cell cultures from a number of species that were non-permissive for VV alone. Limited propagation of VV in some mammalian species would thus appear to be due to an intracellular restriction rather than to absence of VV receptors.
D000818:Animals; D002417:Cattle; D002460:Cell Line; D002522:Chlorocebus aethiops; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D004285:Dogs; D005814:Genes, Viral; D006168:Guinea Pigs; D006801:Humans; D051379:Mice; D011817:Rabbits; D051381:Rats; D011991:Receptors, Virus / Q000378:metabolism*; D012756:Sheep; D013552:Swine; D014721:Vesicular stomatitis Indiana virus / Q000235:genetics / Q000502:physiology; D010948:Viral Plaque Assay; D014790:Visna-maedi virus / Q000378:metabolism* / Q000502:physiology
D011991:Receptors, Virus