title: [Possibilities of systemic fibrinolysis in acute myocardial infarct].
abstract: Recanalisation of the infarct-related coronary artery could be achieved in 60 to 80% of patients with acute myocardial infarction by means of systemic fibrinolysis, if the interval between the onset of symptoms and the admission to therapy was less than 3 (maximal 6) hours. Fibrinolytic therapy should be combined with an exact conventional treatment in form of sedation, analgesia, oxygen delivery and optimisation of hemodynamics and metabolism with nitroglycerin, calcium antagonists and beta-blockers. Coronary angiography should be performed as soon as possible to decide about further therapy like percutaneous transluminal coronary angioplasty, coronary bypass surgery or medical treatment.
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon; D003131:Combined Modality Therapy; D001026:Coronary Artery Bypass; D003326:Coronary Circulation / Q000187:drug effects; D003402:Creatine Kinase / Q000097:blood; D004562:Electrocardiography; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000627:therapeutic use*
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase; D013300:Streptokinase
vernacular_title: Möglichkeiten der systemischen Fibrinolyse bei akutem Myokardinfarkt.