[Diagnostic value of detecting neutralizing antibodies to Coxsackie B enteroviruses in patients with infectious-allergic myocarditis].
The clinical virological survey of 180 cardiological patients aged 16-60 years with clinically diagnosed infectious allergic myocarditis (100), rheumatism (38) and other cardiac diseases (42) was made. A group of 97 practically healthy adults aged 21-60 years was used for control. The survey revealed statistically significant differences in the frequency of occurrence of Coxsackie B virus in healthy persons and in cardiac patients. Thus the criteria of the diagnostic significance of the results of the serologic survey gave grounds for suspicion that diseases in 31.2% of the surveyed patients were connected with the presence of Coxsackie B virus infection. Significantly more frequently Coxsackie B virus infection (predominantly type 4 virus) was found to be associated with infectious allergic myocarditis (42%).
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D003384:Coxsackievirus Infections / Q000175:diagnosis* / Q000276:immunology; D029822:Enterovirus B, Human; D006331:Heart Diseases / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D008875:Middle Aged; D009205:Myocarditis / Q000175:diagnosis*; D009500:Neutralization Tests; D012216:Rheumatic Diseases / Q000276:immunology; D013577:Syndrome
D000914:Antibodies, Viral
Diagnosticheskoe znachenie obnaruzheniia neĭtralizuiushchikh antitel k énterovirusam Koksaki B u bol'nykh infektsionno-allergicheskim miokarditom.