title: Effects of dobutamine on cyclic AMP accumulation induced by the stimulation of dopamine receptors in rabbit retina in vitro.
abstract: Intact rabbit retinae were used for testing in vitro the potential activation of dopamine receptors by a new cardioactive sympathetic amine dobutamine. It was found that despite the structure relationship of dobutamine with other dopamine-analog, the pharmacological action of this compound is not comparable to that of apomorphine, N-methyl-dopamine and/or ADTN.
mesh_terms: D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D002395:Catecholamines / Q000494:pharmacology*; D000242:Cyclic AMP / Q000378:metabolism*; D003846:Deoxyepinephrine / Q000494:pharmacology; D004280:Dobutamine / Q000494:pharmacology*; D004298:Dopamine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005476:Fluphenazine / Q000494:pharmacology*; D011817:Rabbits; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*; D012160:Retina / Q000187:drug effects / Q000378:metabolism*
chemical_list: D002395:Catecholamines; D011954:Receptors, Dopamine; D004280:Dobutamine; D000242:Cyclic AMP; D001058:Apomorphine; D003846:Deoxyepinephrine; D005476:Fluphenazine; D004298:Dopamine