Inhibition of cyclic AMP phosphodiesterase by 5'-deoxy-5'-S-isobutylthioadenosine at biologically active concentrations of drug.
D015762:2-Chloroadenosine; D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002772:Cholera Toxin / Q000494:pharmacology; D003839:Deoxyadenosines / Q000031:analogs & derivatives* / Q000494:pharmacology; D004789:Enzyme Activation; D007545:Isoproterenol / Q000494:pharmacology; D007700:Kinetics; D008214:Lymphocytes / Q000201:enzymology; D051379:Mice; D011458:Prostaglandins E / Q000494:pharmacology; D013872:Thionucleosides / Q000494:pharmacology*
D000970:Antineoplastic Agents; D003839:Deoxyadenosines; D011458:Prostaglandins E; D013872:Thionucleosides; D015762:2-Chloroadenosine; C013919:5'-deoxy-5'-S-isobutylthioadenosine; D002772:Cholera Toxin; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases; D000241:Adenosine; D007545:Isoproterenol