title: [In vivo and in vitro activity of Streptococcus faecium extract on Herpes simplex virus].
abstract: The effects of substance or substance extracted from Str. faecium SF 68 on HSV-1 are evaluated. The "in vivo" assay show that bacterial extract introduced i.p. in mice simultaneously with HSV-1 brought about 100% of survival, but bacterial extract after virus challenge brought about complete mortality of mice. "In vitro" assays show that bacterial extract reduce significantly PFU number. It seemed that Str. faecium extract affected the virus at the stage of adsorption on the host cells.
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D018139:Simplexvirus / Q000187:drug effects*; D013291:Streptococcus / Q000502:physiology*
chemical_list: D000998:Antiviral Agents
vernacular_title: Attivita' "in vivo" ed "in vitro" di un estratto di Streptococcus faecium su Herpes simplex virus.