Glial fibrillary acidic protein in monolayer cultures of C-6 glioma cells: effect of aging and dibutyryl cyclic AMP.
Aging induced a dramatic increase in the number of glial fibrillary acidic protein (GFA) positive cells in monolayer cultures of C-6 cells. Dibutyryl cyclic AMP (DBcAMP) had a similar effect on subconfluent cultures. Both aging and DBcAMP treatment also helped C-6 cells to develop mature astroglia like morphology.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D002460:Cell Line; D005455:Fluorescent Antibody Technique; D005904:Glial Fibrillary Acidic Protein; D005910:Glioma / Q000378:metabolism*; D006651:Histocytochemistry; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D005904:Glial Fibrillary Acidic Protein; D009419:Nerve Tissue Proteins; D003994:Bucladesine