title: Onset of progeny immunity against viral arthritis/tenosynovitis after experimental vaccination of parent breeder chickens and cross-immunity against six reovirus isolates.
abstract: Immunization of breeder chickens by eyedrop with viral arthritis/tenosynovitis vaccine strain S1133 (73rd egg passage) gave no immunity against day-old oral challenge of their progeny at 1 week postvaccination of the breeders, but progeny immunity was observed at 3, 4, 5, 6, and 7 weeks postvaccination of the breeders. Oral cross-challenge of immune progeny with viral isolates from Connecticut, West Virginia, California, Indiana, Pennsylvania, and Minnesota showed that in vitro neutralization of an isolate by anti-S1133 antiserum correlated with in vivo immunity of the progeny against oral day-old challenge with such an isolate.
mesh_terms: D000818:Animals; D001170:Arthritis, Infectious / Q000276:immunology / Q000662:veterinary*; D002645:Chickens / Q000276:immunology*; D003429:Cross Reactions; D007112:Immunity, Maternally-Acquired; D009500:Neutralization Tests; D011201:Poultry Diseases / Q000276:immunology*; D012087:Reoviridae / Q000276:immunology*; D012088:Reoviridae Infections / Q000276:immunology / Q000662:veterinary*; D013717:Tenosynovitis / Q000276:immunology / Q000662:veterinary*; D014611:Vaccination / Q000662:veterinary*