A micro-neutralization test for flavivirus antibodies.
A micro-neutralization test for the detection of flavivirus antibodies is described. The test utilizes the PS line of cells in flat bottomed microtiter plates to detect the neutralization of cytopathic effect by specific antibodies. Cross-neutralization of flaviviruses found in Southeast Asia with homologous and heterologous hyperimmune mouse ascitic fluids revealed the test to be specific. The test is simple and inexpensive to perform.
D000914:Antibodies, Viral / Q000032:analysis*; D001210:Asia, Southeastern; D005416:Flavivirus / Q000276:immunology*; D066298:In Vitro Techniques; D009500:Neutralization Tests / Q000379:methods
D000914:Antibodies, Viral