Genesis of concentric laminated inclusions in the nucleus.
Single-membrane-bound inclusions containing zymogen granules were found in pancreatic acinar cells. Images were seen suggesting that the concentric laminated inclusion is derived by hydration and fusion of such granules within the inclusion.
D002459:Cell Fusion; D002462:Cell Membrane; D002467:Cell Nucleus / Q000648:ultrastructure*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D010179:Pancreas / Q000648:ultrastructure