Growth failure in vitamin D-deficient rat pups.
Vitamin D-deficient rat pups were produced by feeding normal impregnated rats a diet deficient in vitamin D after mating. The rat pups appeared normal at birth but stopped growing at 1 week of age. Despite this growth failure, these pups were normocalcemic. Analyses of calvaria from a similar group of dams given vitamin D3 showed that these dams mobilized skeletal calcium to meet the calcium requirements of their growing pups.
D000818:Animals; D002118:Calcium / Q000097:blood / Q000172:deficiency / Q000378:metabolism; D002762:Cholecalciferol / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D006130:Growth Disorders / Q000209:etiology*; D007774:Lactation; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D051381:Rats; D014808:Vitamin D Deficiency / Q000150:complications* / Q000378:metabolism
D002762:Cholecalciferol; D002118:Calcium