title: Evaluation of cerebral blood flow in the normal neonate by Doppler spectrum analysis.
abstract: Continuous wave Doppler ultrasound has seldom been applied to the evaluation of the cerebral circulation of the newborn infant. Twenty-five term infants were studied and records taken from the common carotid and anterior cerebral arteries during the first week of life using a bidirectional Doppler instrument. The best Doppler signals obtained were audiofrequency analysed and sonagrams recorded. Analysis of the carotid sonagrams revealed a mean Pulsatility Index (PI) on the first day of life of 0.98 compared to 0.88 on Day 2 (p less than 0.001). An unexpected finding was the absence of continuous carotid blood flow in the majority of infants in the first hours of life. The PI on subsequent days did not differ significantly from Day 2. The PI of the anterior cerebral arteries on Day 1 was significantly elevated (p less than 0.001) compared to Day 2 and subsequent days. The significance of these findings and their importance in the further evaluation of pathological cerebral states in the neonate, especially birth asphyxia and intracranial haemorrhage are discussed.
mesh_terms: D001238:Asphyxia Neonatorum / Q000175:diagnosis; D002339:Carotid Arteries / Q000502:physiology; D002536:Cerebral Arteries / Q000502:physiology; D002543:Cerebral Hemorrhage / Q000175:diagnosis; D002560:Cerebrovascular Circulation; D005069:Evaluation Studies as Topic; D006801:Humans; D007231:Infant, Newborn; D012212:Rheology; D014463:Ultrasonography; D014655:Vascular Resistance