title: Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome.
abstract: A polyoma virus mutant that maps in the early region between the known hr-t and ts-a mutants has been isolated. Its 66-base-pair deletion results in structural changes in both medium and large T-antigens but causes no substantial alterations in viral replication or cell transformation.
mesh_terms: D000956:Antigens, Viral / Q000235:genetics*; D001483:Base Sequence; D002472:Cell Transformation, Viral; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D009154:Mutation; D011120:Polyomavirus / Q000235:genetics* / Q000276:immunology / Q000502:physiology
chemical_list: D000956:Antigens, Viral; D004279:DNA, Viral