Spontaneous nephroblastoma in Sprague-Dawley rats.
Pathological findings were described on nephroblastomas occurrred spontaneously in 3 young Sprague-Dawley rats. One side of kidneys was affected in each animal. Microscopically, the tumors consisted of epithelial elements showing undifferentiated to well-differentiated tubular arrangements, sometimes with glomeruloid and glomerular structures. A metastatic tumor nodule was found in the lung of one rat.
D000818:Animals; D005260:Female; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000473:pathology / Q000662:veterinary*; D008297:Male; D051381:Rats; D012376:Rodent Diseases / Q000473:pathology*; D009396:Wilms Tumor / Q000473:pathology / Q000662:veterinary*