Antagonism of calmodulin by local anesthetics, mepacrine, and propranolol.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism; D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000378:metabolism; D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000201:enzymology; D002135:Calcium-Binding Proteins / Q000494:pharmacology*; D000252:Calcium-Transporting ATPases / Q000097:blood*; D002147:Calmodulin / Q000494:pharmacology*; D004336:Drug Antagonism; D004789:Enzyme Activation; D004910:Erythrocyte Membrane / Q000201:enzymology; D006801:Humans; D007700:Kinetics; D011433:Propranolol / Q000494:pharmacology*; D011796:Quinacrine / Q000494:pharmacology*; D051381:Rats
D000779:Anesthetics, Local; D002135:Calcium-Binding Proteins; D002147:Calmodulin; D011433:Propranolol; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D000252:Calcium-Transporting ATPases; D011796:Quinacrine