Krukenberg carcinoma of the ovary with bone marrow involvement. Report of 2 cases and review of the literature.
Krukenberg carcinoma of the ovary accounts for 1 to 3% of ovarian neoplasms. The nature and behavior of this particularly virulent tumor remain unclear. In this paper, 2 cases are presented of Krukenberg carcinoma metastatic from the gastrointestinal tract; in both bone marrow involvement was detected early in the course of the disease. The histopathology of the tumor is described. A comprehensive review of the literature in English is provided, and therapeutic approaches to the disease are discussed.
D000328:Adult; D001853:Bone Marrow / Q000473:pathology*; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007725:Krukenberg Tumor / Q000473:pathology / Q000556:secondary*; D010051:Ovarian Neoplasms / Q000473:pathology / Q000556:secondary*; D011706:Pyloric Antrum / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology*