[Metformin induced lactic acidosis. Two new cases (author's transl)].
Two cases of severe lactic acidosis, following a metformin treatment are presented. A continued treatment in spite of the occurrence of renal failure, was responsible for this lactic acidosis. Indeed the metformin elimination is assured by kidney in 80%. Renal function must be evaluated before and during metformin treatment. Treatment must be stopped when any trouble of renal function appeared.
D000138:Acidosis / Q000097:blood / Q000139:chemically induced*; D000368:Aged; D005260:Female; D006801:Humans; D007773:Lactates / Q000097:blood*; D008297:Male; D008687:Metformin / Q000009:adverse effects*
D007773:Lactates; D008687:Metformin
Acidose lactique à la metformine. Deux nouveaux cas.