Perinatal neuropathy as an early manifestation of Krabbe's disease.
An asymptomatic child with antenatally diagnosed globoid cell leukodystrophy was found to have electrodiagnostic evidence of peripheral neuropathy at 7 weeks of age. The earliest prior such evidence in the literature was in a 6-month-old-child. Thus, peripheral neuropathy can be both the initial manifestation and a very early finding in Krabbe's disease.
D004568:Electrodiagnosis; D005260:Female; D006801:Humans; D007223:Infant; D007965:Leukodystrophy, Globoid Cell / Q000175:diagnosis*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis