[Effect of age and sex on the nondenaturing dissolution of rat lung collagen].
The collagen of the lung was found highly soluble after several short-lasting treatments with pepsin following incubation of the tissue in a medium containing LiCl 9 M. Whatever age and sex, almost all the collagen content was solubilized. The rate of dissolution was observed to be highly increased during a short time of life-between 7 and 14 weeks. This high rate correlates with the end of the ponderal growth of the lung.
D000375:Aging; D000818:Animals; D002712:Chlorides; D003094:Collagen / Q000378:metabolism*; D003460:Crystallization; D005260:Female; D008094:Lithium; D018021:Lithium Chloride; D008168:Lung / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D010434:Pepsin A; D051381:Rats; D012737:Sex Factors; D012995:Solubility
D002712:Chlorides; D003094:Collagen; D008094:Lithium; D010434:Pepsin A; D018021:Lithium Chloride
Effet de l'âge et du sexe sur la dissolution non dénaturante du collagène pulmonaire de Rat.