Mutation in the crp gene of Salmonella typhimurium which interferes with inducer exclusion.
A mutation in the crp gene of Salmonella typhimurium is described which overcame the defects of ptsHI deletion mutants for growth on a number of nonphosphotransferase system compounds. This mutation abolished inducer exclusion in a leaky ptsI mutant. The possible implications for the mechanism of inducer exclusion are discussed.
D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism / Q000494:pharmacology; D005990:Glycerol / Q000378:metabolism; D008320:Maltose / Q000378:metabolism; D008553:Melibiose / Q000378:metabolism; D008757:Methylglucosides / Q000494:pharmacology; D009154:Mutation; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000235:genetics*; D012486:Salmonella typhimurium / Q000235:genetics* / Q000378:metabolism
D002352:Carrier Proteins; D008757:Methylglucosides; D008320:Maltose; D008553:Melibiose; D000242:Cyclic AMP; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; D005990:Glycerol