In vitro activities of cefotaxime and moxalactam (LY127935) against Haemophilus influenzae.
The in vitro activities of two new beta-lactam antibiotics, cefotaxime and moxalactam (LY127935), were compared with those of cefamandole, cefoxitin, cefuroxime, and ampicillin against both beta-lactamase-producing and non-beta-lactamase-producing isolates of Haemophilus influenzae. Both cefotaxime and LY127935 were highly active against all isolates irrespective of beta-lactamase production.
D000667:Ampicillin / Q000494:pharmacology; D002439:Cefotaxime; D002511:Cephalosporins / Q000494:pharmacology*; D002513:Cephamycins / Q000494:pharmacology*; D006193:Haemophilus influenzae / Q000187:drug effects; D009070:Moxalactam; D010403:Penicillin Resistance; D013045:Species Specificity
D002511:Cephalosporins; D002513:Cephamycins; D000667:Ampicillin; D002439:Cefotaxime; D009070:Moxalactam