[Effect of ginseng preparations on the activity of identified neurons of Heliz lucorum snails].
It has been demonstrated that the effects of aqueous extracts from the native ginseng and extracts of genseng tissue culture on the activity of identified neurones are identical. Neuronal excitability, tested intracellularly, significantly increases to the 60th minute of drug application, whereas gradually developing depolarization simultaneously disappears. Rhythmic orthodromic stimulation revealed the increase in neuronal responses during ginseng perfusion, the synaptic efficiency remaining constant. It is suggested that changes in transmembrane potential level evoked by administration of ginseng preparations are not related to changes in the excitability. Changes in the adaptive capacities of the neurones in invertebrate animals are due to nonspecific endoneuronal shifts in cellular metabolism induced by ginseng administation.
D000818:Animals; D046508:Culture Techniques; D004558:Electric Stimulation; D006372:Helix, Snails; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects*; D005894:Panax; D010507:Periodicity; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D009435:Synaptic Transmission / Q000187:drug effects
D010936:Plant Extracts
Vliianie preparatov zhen'shenia na aktivnost' identifitsirovannykh neĭronov ulitki Helix lucorum.