Mechanism of action of choleragen and E. coli heat-labile enterotoxin: activation of adenylate cyclase by ADP-ribosylation.
D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000262:Adenylyl Cyclases / Q000378:metabolism*; D002147:Calmodulin / Q000494:pharmacology; D002772:Cholera Toxin / Q000494:pharmacology*; D003600:Cytosol / Q000378:metabolism; D004768:Enterotoxins / Q000494:pharmacology*; D004789:Enzyme Activation; D004926:Escherichia coli; D005677:G(M1) Ganglioside / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism*; D009713:Nucleotidyltransferases / Q000378:metabolism; D011065:Poly(ADP-ribose) Polymerases
D002147:Calmodulin; D004768:Enterotoxins; D008081:Liposomes; D009702:Nucleoside Diphosphate Sugars; D000246:Adenosine Diphosphate Ribose; D005677:G(M1) Ganglioside; D006160:Guanosine Triphosphate; D002772:Cholera Toxin; D011065:Poly(ADP-ribose) Polymerases; D009713:Nucleotidyltransferases; D000262:Adenylyl Cyclases