title: [Effect of training and physical load on 3':5'-AMP content and activity fo the enzymes of its metabolism in rat muscle].
abstract: It is established tha in skeletal muscles of dormant animals under the influence of training the  3':5'-AMP content and the activity of adenylate cyclase increase; that of phosphodiesterase remains unchanged. A long physical load causes no changes in the 3':5"-AMP content in the skeletal muscles of the trained rats as compared to its content in the intact animals but evokes a decrease as compared to its level in the trained rats muscles. The activity of adenylate cyclase in the skeletal muscles of the trained rats under long physical load lowers, that of 3':5'-AMP phosphodiesterase also decreases but to a less extent. The found changes in the 3':5'-AMP metabolism in the trained animals skeletal muscles evidence for a possible participation of the 3':5'-AMP system in development of the organism adaptation to higher physical loads.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D008297:Male; D009132:Muscles / Q000378:metabolism*; D005082:Physical Exertion; D051381:Rats
chemical_list: D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases
vernacular_title: Vliianie trenirovki i fizicheskoí nagruzki na soderzhanie 3':5'-AMP i aktivnost fermentov ego ovmena v myshtsakh krys.