title: Parasitological, serological and clinical effects of continuous graded levels of Dictyocaulus viviparus inoculations in calves.
abstract: To investigate the parasitological, serological, clinical and growth effects of continuous graded levels of Dictyocaulus viviparus inoculations in calves an experiment was carried out with 10 groups of 5 calves each. Calves were inoculated twice a week during a period of ten weeks. The range of the doses was 10-2560 infective larvae (L3) per inoculation. The results were analysed by linear and curvilinear regression of various traits on infection level. It is concluded that: A continuous exposure of calves to L3 of D. viviparus was followed by a continuous larval excretion at all levels; Results of the ELISA technique gave a very good reflection of the level of infection; Clinical signs and weight loss were evident before the parasitological and serological results were positive; The serological parameter and the parasitological parameters were mainly linearly related to the level of infection. The clinical parameters were mainly cubically related to the level of infection.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D001835:Body Weight; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000469:parasitology* / Q000503:physiopathology; D004021:Dictyocaulus / Q000276:immunology; D004022:Dictyocaulus Infections / Q000276:immunology / Q000469:parasitology* / Q000503:physiopathology; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000469:parasitology; D008168:Lung / Q000469:parasitology; D008297:Male; D012119:Respiration; D013183:Sputum / Q000469:parasitology
chemical_list: D000906:Antibodies