Sex-dimorphic behavior in childhood subsequent to prenatal exposure to exogenous progestogens and estrogens.
Thirteen boys and 15 girls with a history of prenatal exposure to medroxyprogesterone acetate only and 22 boys and 15 girls with exposure to a variety of progestogens and estrogens singly or in combination were studied at age 8-14 years in comparison to closely pair-matched, unexposed controls. This report concerns the findings on sex-dimorphic behavior as assessed by separate interviews with the child and his/her mother. Hormone-exposed boys and controls differed little, while in girls prenatal sex hormone treatment seemed to be associated with some degree of increased stereotypic femininity.
D000293:Adolescent; D002648:Child; D004967:Estrogens / Q000009:adverse effects*; D005260:Female; D005783:Gender Identity; D006801:Humans; D007062:Identification, Psychological; D008297:Male; D008525:Medroxyprogesterone / Q000009:adverse effects / Q000031:analogs & derivatives; D017258:Medroxyprogesterone Acetate; D009048:Motor Skills / Q000187:drug effects; D010379:Peer Group; D010988:Play and Playthings; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011372:Progestins / Q000009:adverse effects*; D013177:Sports
D004967:Estrogens; D011372:Progestins; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone