title: Relationship of internal cyclic AMP levels, rates of protein synthesis and mucor dimorphism.
abstract: Changes in the intracellular pools of cyclic AMP and specific rates of protein synthesis have been described as correlates of the yeast-to-hypha conversion in Mucor racemosis. A further examination of the relationship between these physiological parameters and the cellular morphogenesis was conducted in the present study. The levels of intracellular cyclic AMP consistently varied as a function of the cell morphology rather than the CO2 tension, oxygen tension or growth rate. The specific rate of protein synthesis failed to change during a N2-to-air-induced yeast-to-hypha transition. Previously reported changes in this parameter during CO2-to-air- and CO2-to-N2-induced yeast-to-hypha shifts may be a consequence of growth rate changes rather than development per se.
mesh_terms: D002245:Carbon Dioxide / Q000378:metabolism; D002454:Cell Differentiation; D000242:Cyclic AMP / Q000378:metabolism*; D005656:Fungal Proteins / Q000096:biosynthesis*; D009024:Morphogenesis; D009089:Mucor / Q000166:cytology* / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism
chemical_list: D005656:Fungal Proteins; D002245:Carbon Dioxide; D000242:Cyclic AMP; D009584:Nitrogen