The reconstitution of human C1, the first complement component: binding of C1r and C1s to C1q influences the C1q conformation.
D003166:Complement Activating Enzymes; D003172:Complement C1; D015922:Complement C1q; D015923:Complement C1r; D003173:Complement C1s; D004792:Enzyme Precursors; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007141:Immunoglobulin Fc Fragments; D046911:Macromolecular Substances; D011485:Protein Binding; D011487:Protein Conformation; D014357:Trypsin / Q000378:metabolism
D003172:Complement C1; D004792:Enzyme Precursors; D007141:Immunoglobulin Fc Fragments; D046911:Macromolecular Substances; D015922:Complement C1q; D003166:Complement Activating Enzymes; D014357:Trypsin; D015923:Complement C1r; D003173:Complement C1s