[The course of flavivirus infections in mice in the presence of the graft versus host reaction under conditions of 2-way incompatibility].
The graft versus host reaction (GVHR) under conditions of two-way incompatibility was shown to increase average longevity (AL) of mice with experimental tick-borne encephalitis (TBE) and to activate asymptomatic infection caused by Langat virus. Experiments with TBE virus demonstrated participation of viable T lymphocytes in GVHR. Inhibition of function of both humoral and cellular immunity was shown to occur in GVHR. The assumption that the increase in the average longevity in TBE is associated with the inhibition of the damaging function of cellular immunity is experimentally substantiated.
D000818:Animals; D001102:Arbovirus Infections / Q000276:immunology*; D004669:Encephalitis Viruses, Tick-Borne; D004675:Encephalitis, Tick-Borne / Q000276:immunology; D006087:Graft vs Host Reaction; D007111:Immunity, Cellular; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains
Techenie flavivirusnykh infektsiĭ u mysheĭ na fone reaktsii transplantat protiv khoziaina v usloviiakh dvustoronneĭ nesovmestimosti.