title: [Diffusion of cefotaxime in the interstitial fluid of rabbits. Comparison with cefazolin, cefoxitin and cefamandole (author's transl)].
abstract: The diffusion of cefotaxime compared with that of cefazolin, cefoxitin and cefamandole in the interstitial fluid has been studied in rabbits. The different antibiotics were administered intramuscularly at a dose of 30 mg/kg by injection. Serum concentrations were determined at 30 minutes, 2, 4, 8 and 12 hours following the injection.
mesh_terms: D000818:Animals; D002435:Cefamandole / Q000378:metabolism; D002437:Cefazolin / Q000378:metabolism; D002439:Cefotaxime; D002440:Cefoxitin / Q000378:metabolism; D002511:Cephalosporins / Q000378:metabolism*; D004058:Diffusion; D005110:Extracellular Space / Q000378:metabolism*; D011817:Rabbits
chemical_list: D002511:Cephalosporins; D002435:Cefamandole; D002440:Cefoxitin; D002437:Cefazolin; D002439:Cefotaxime
vernacular_title: Etude de la diffusion du céfotaxime dans le liquide interstitiel du lapin. Comparaison avec la céfazoline, la céfoxitine, le céfamandole.