title: [Certain properties of the Aujeszky live vaccine "Dessau" with special reference to laboratory diagnostic aspects].
abstract: Aujeszky live vaccine "Dessau" proved to be apathogenetic to and unconditionally tolerable by pigs of all age groups, including pregnant sows. Transmission of Herpes virus suis vaccine strain from immunised individuals to non-immunised contact animals was not observed at all. Higher titres of virus-neutralising serum antibody with longer persistence were not attained until repeated vaccinations had been applied, using Aujeszky live vaccine "Dessau". Spherical detachment of single cells was the only manifestation in fowl embryo cell cultures to demonstrate the cytopathic action of the Herpes virus suis strain which had been used in the preparation of Aujeszky live vaccine "Dessau". This high-stability marker of Herpes virus suis vaccine strain "Tornau" can be readily and dependently differentiated from Herpes suis field strains with cytopathic effects in fowl embryo cell cultures which include not only spherical detachment of single cells but, as well, differentiated portions of giant cells. Those are the properties of Aujeszky live vaccine "Dessau" which provide favourable conditions for laboratory diagnosis to monitor the incidence of Aujeszky's disease in areas with different degrees of contamination.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D011558:Herpesvirus 1, Suid / Q000276:immunology* / Q000472:pathogenicity; D011557:Pseudorabies / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D014765:Viral Vaccines / Q000276:immunology*; D014774:Virulence
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Zu einigen Eigenschaften des Aujeszky-Lebendimpfstoffes "Dessau" unter besonderer Berücksichtigung labordiagnostischer Aspekte.