[Hypothesis concerning the role of random connections between cerebral nerve cells].
It is proposed that molecular computers (MC) of neurons monitor the external physio-chemical situation by cell surface receptors. This situation is created by mediators released from other neurons. DNA is propose to contain not only the usual cell biochemistry function programs, but also the programs for animal behavior problem solving. These latter programs are used by neuron MC in response to the mediator distribution pattern (MDP). This contrast chemical picture on the nerve cell membrane is made by the nerve impulses. Different time-distribution of nerve impulses leads to different MDP's. This special decoding of impulse sequences takes place because nerve fiber branches have a different refractory period and a different calcium threshold for mediator releasing. MDP is used as a code number of the MC solving problems. The redundant coding by random selected MDP's is used for increasing reliability. Such MDP's can be built by random branching of nerve fibers and thus mosaics of synapses differ from one individual to another. Thus an extensive application of random connections does not prevent the effective work of the MC system.
D001369:Axons / Q000502:physiology; D055592:Biophysical Phenomena; D001703:Biophysics; D001921:Brain / Q000502:physiology*; D002118:Calcium / Q000502:physiology; D003201:Computers; D000242:Cyclic AMP / Q000502:physiology; D006152:Cyclic GMP / Q000502:physiology; D004247:DNA / Q000502:physiology; D006801:Humans; D008959:Models, Neurological; D012333:RNA, Messenger / Q000502:physiology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission
D012333:RNA, Messenger; D004247:DNA; D000242:Cyclic AMP; D006152:Cyclic GMP; D002118:Calcium
Gipoteze o roli sluchaĭnykh sviazeĭ mezhdu nervnymi kletkami mozga.