Huntington disease and Tourette syndrome. I. Electron spin resonance of bed ghosts.
Abnormalities in the electron spin resonance (ESR) of nitroxide-labeled red blood cell membranes have been reported in Huntington disease (HD). Because of the importance of verifying a general membrane defect in this disease, we have examined 13 unmedicated HD patients of all grades of severity, with a duration of symptoms from 3 to 20 years and including juvenile and rigid cases. No significance differences in the ESR of controls, HD patients, and three Tourette syndrome patients were found.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004578:Electron Spin Resonance Spectroscopy; D004910:Erythrocyte Membrane; D004912:Erythrocytes; D006801:Humans; D006816:Huntington Disease / Q000097:blood*; D008875:Middle Aged; D013113:Spin Labels; D005879:Tourette Syndrome / Q000097:blood*
D013113:Spin Labels