Rat pregnancy induces two suppressor cell activities.
Pregnancy in rat is able to stimulate two suppressor cell activities. One is specific to the paternal histocompatibility antigens and it resides in the T-lymphocyte population. The second is nonspecific and is of non-T nature. The use of various methods for pseudopregnancy and deciduoma installation has allowed the demonstration of two inducing circuits: (a) the presence of fertilized ova in the female genital tract and (b) the progestation hormonal status.
D000818:Animals; D003656:Decidua / Q000276:immunology; D005260:Female; D006649:Histocompatibility Antigens / Q000276:immunology; D011247:Pregnancy; D011270:Pregnancy, Animal; D011372:Progestins / Q000276:immunology; D011555:Pseudopregnancy / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D015053:Zygote / Q000276:immunology
D006649:Histocompatibility Antigens; D011372:Progestins