Leishmaniasis recidivans treated with sodium stibogluconate.
Two cases of leishmaniasis recidivans of twenty years' duration were treated intravenously with sodium stibogluconate (Pentostam) with good results. Before treatment, histologic examination of a biopsy specimen revealed many Leishman-Donovan (LD) bodies. After treatment, repeated biopsies done in one of the cases revealed only scar tissue. We recommended treatment with sodium stibogluconate in cases of leishmaniasis recidivans, although an ideal treatment for this condition still does not exist.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000965:Antimony / Q000627:therapeutic use; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use*; D005942:Gluconates / Q000627:therapeutic use*; D006801:Humans; D007896:Leishmaniasis / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008536:Meglumine / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D008875:Middle Aged; D009942:Organometallic Compounds; D012008:Recurrence
D000900:Anti-Bacterial Agents; D005942:Gluconates; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony; D000967:Antimony Sodium Gluconate