Effects of scavengers of superoxide radicals, hydrogen peroxide, singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes.
Superoxide dismutase, catalase and sodium formate did not inhibit the formation of malondialdehyde (MDA) from arachidonic acid, suggesting that O2-., H2O2 and OH. are not involved in the enzymatical oxidation of arachidonic acid. Sodium azide was found to be an inhibitor of MDA production.
D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism*; D002417:Cattle; D005609:Free Radicals; D006861:Hydrogen Peroxide / Q000378:metabolism; D006878:Hydroxides / Q000378:metabolism; D008297:Male; D008314:Malonates / Q000096:biosynthesis*; D008315:Malondialdehyde / Q000096:biosynthesis*; D008861:Microsomes / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D012669:Seminal Vesicles / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism
D001095:Arachidonic Acids; D005609:Free Radicals; D006878:Hydroxides; D008314:Malonates; D013481:Superoxides; D008315:Malondialdehyde; D006861:Hydrogen Peroxide; D010100:Oxygen