Influence of the thyroid hormones on erythropoiesis and radiation resistance in C 57 black mice.
Oral administration of dried thyroid gland to C57Bl adult male mice in a dose of 0.6 g per 100 g diet during 10 days increased the metabolic rate and stimulated the erythropoiesis. Three to six days after thyroid pretreatment the radiation resistance of the mice increased, as revealed by their 30-day survival and a higher recovery of peripheral blood cell counts. The period of increased resistance to radiation was correlated with the receding of hypermetabolic effects and with the increase of repopulating abilities of the bone marrow cells.
D000818:Animals; D001772:Blood Cell Count; D004920:Erythropoiesis / Q000187:drug effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011829:Radiation Dosage; D011836:Radiation Tolerance; D013962:Thyroid (USP) / Q000494:pharmacology*; D013963:Thyroid Hormones / Q000494:pharmacology*
D013962:Thyroid (USP); D013963:Thyroid Hormones