Inhibition of nitrosamine formation by ascorbic acid: participation of free radicals in its anaerobic reaction with nitrite.
The participation of semiquinone free radicals during the reaction of ascorbic acid with acidified sodium nitrite has been demonstrated by ESR spectroscopy unambiguously for the first time. Scavenging of the nitrosating agent, reflected by the observed free radical concentration, unexpectedly occurs with scarcely varying efficiency over the pH range 0.1--4.5.
D000693:Anaerobiosis; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D009573:Nitrites; D009602:Nitrosamines; D010084:Oxidation-Reduction
D005609:Free Radicals; D009573:Nitrites; D009602:Nitrosamines; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid