[Cutaneous and muscular unmyelinated afferent fibres. Clinical, histological and experimental study. Possible explanation of muscular cramps (author's transl)].
Unmyelinated afferent fibres are the most numerous of the whole afferent component. Their function in nociception is now well established. However some recent data allow to think that their function is much more complex. Cutaneous unmyelinated afferences are evaluated in controls and in 3 groups of patients (painful neuropathies, painless neuropathies with hypesthesia, diabetic neuropathies). Amyelinic myelinic ratio is not in accordance with the gate control theory. Muscular afferent fibres are studied, especially the lateral gastrocnemius soleus nerve of cat. Their predominance is obvious. Our study was conducted by recording single unit activity from a micro electrod inserted in dorsal root ganglia. But 45% of unmyelinated fibres are not activated by various algesic stimuli. It is suggested that they have a function in cardio-pulmonary adaptation to effort and possibly segmental vascular control as homonymous reflex effect on moto-neuron. Their several properties are a possible explanation of muscular cramps.
D000328:Adult; D000344:Afferent Pathways / Q000473:pathology / Q000502:physiology; D000368:Aged; D006801:Humans; D008875:Middle Aged; D009120:Muscle Cramp / Q000473:pathology* / Q000503:physiopathology; D009132:Muscles / Q000294:innervation*; D009412:Nerve Fibers / Q000473:pathology* / Q000502:physiology / Q000503:physiopathology; D012867:Skin / Q000294:innervation*
Les afférences amyéliniques cutanées et musculaires. Etude anatomo-clinique et expérimentale, application aux crampes musculaires.