[Cholinergic sympathetic influences on blood flow and cyclic nucleotide concentration in skeletal muscles].
The content of 3.5 cGMP increased twofold and the content of 3.5 cAMP remained unchanged in the cat skeletal muscle during vasodilatation evoked by hypothlalamic stimulation. Cholinergic vasodilatation increased also phosphorylase activity by 90%. These effects were blocked by atropine. Possible existence of an interrelationship among the vasodilator effect, phosphorylase activity and increase in cGMP, is discussed.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002415:Cats; D002799:Cholinergic Fibers / Q000502:physiology; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D004789:Enzyme Activation; D007031:Hypothalamus / Q000502:physiology*; D007032:Hypothalamus, Anterior / Q000502:physiology*; D009132:Muscles / Q000032:analysis / Q000098:blood supply / Q000294:innervation*; D006005:Phosphorylases / Q000378:metabolism; D014664:Vasodilation
D001285:Atropine; D000242:Cyclic AMP; D006005:Phosphorylases; D006152:Cyclic GMP
Kholinergicheskie simpaticheskie vliianiia na krovotok i soderzhanie tsiklicheskikh nukletotidov v skeletnykh myshtsakh.