[In vitro activity of cefotaxime on anaerobes (author's transl)].
The comparative activity of cefotaxime, cefazolin, cefamandole and cefoxitin was studied on 80 strains of anaerobic bacterial species: 14 Clostridia, 60 Bacteroides fragilis, 6 Peptococcus. The new cephalosporins showed an increase in the in vitro activity against Bacteroides fragilis, but their efficacy was still inferior to that of the 5-nitro-imidazole derivatives.
D000693:Anaerobiosis; D001419:Bacteria / Q000187:drug effects*; D001441:Bacteroides fragilis / Q000187:drug effects; D002439:Cefotaxime; D002511:Cephalosporins / Q000494:pharmacology*; D003016:Clostridium perfringens / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010460:Peptococcus / Q000187:drug effects
D002511:Cephalosporins; D002439:Cefotaxime
Activité antibactérienne in vitro du céfotaxime sur les bactéries anaérobies.