title: Effects of wastewater sludge and its detergents on the stability of rotavirus.
abstract: Wastewater sludge reduced the heat required to inactivate rotavirus SA-11, and ionic detergents were identified as the sludge components responsible for this effect. A similar result was found previously with reovirus (R. L. Ward and C. S. Ashley, Appl. Environ. Microbiol 36:889-897, 1978). The quantitative effects of individual ionic detergents on rotavirus and reovirus were very different, and rotavirus was found to be extremely sensitive to several of these detergents. However, neither virus was destabilized by nonionic detergents. On the contrary, rotavirus was stabilized by a nonionic detergent against the potent destabilizing effects of the ionic detergent sodium dodecyl sulfate. The destabilizing effects of both cationic and anionic detergents on rotavirus were greatly altered by changes in the pH of the medium.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003902:Detergents / Q000494:pharmacology*; D000882:Haplorhini; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D012328:RNA Viruses / Q000187:drug effects*; D012401:Rotavirus / Q000187:drug effects*; D012722:Sewage / Q000032:analysis*; D014776:Virus Cultivation
chemical_list: D003902:Detergents; D012722:Sewage