Insulin stimulation of pyruvate dehydrogenase in an isolated plasma membrane-mitochondrial mixture occurs by activation of pyruvate dehydrogenase phosphatase.
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000273:Adipose Tissue / Q000201:enzymology; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology*; D003208:Concanavalin A / Q000494:pharmacology; D003999:Dichloroacetic Acid / Q000494:pharmacology; D004789:Enzyme Activation; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D008297:Male; D008928:Mitochondria / Q000201:enzymology*; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D011769:Pyruvate Dehydrogenase (Lipoamide)-Phosphatase / Q000378:metabolism*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism*; D051381:Rats; D012969:Sodium Fluoride / Q000494:pharmacology
D007328:Insulin; D011768:Pyruvate Dehydrogenase Complex; D003208:Concanavalin A; D000255:Adenosine Triphosphate; D012969:Sodium Fluoride; D003999:Dichloroacetic Acid; D010749:Phosphoprotein Phosphatases; D011769:Pyruvate Dehydrogenase (Lipoamide)-Phosphatase