Breast cancer and TRH -- response.
The study was made in an effort to determine the thyroid function of breast cancer patients. Plasma TBC levels, plasma TSH basal levels and the TSH levels after stimulating with TRH were evaluated in 37 postmenopausal cancer patients and 30 age matched controls. Neither TBC and TSH basal levels nor stimulated TSH levels were significantly different between the controls and the various stages of cancer patients. Thus, the study cannot confirm other reports suggesting a possible role of thyroid in the development of breast cancer.
D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011863:Radioimmunoassay; D011956:Receptors, Cell Surface / Q000097:blood; D011988:Receptors, Thyroid Hormone; D013972:Thyrotropin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone / Q000097:blood*
D011956:Receptors, Cell Surface; D011988:Receptors, Thyroid Hormone; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin