Long lasting amplification and deformation of thyroid receptors after thyrotropin (TSH) and gonadotropin (GTH) treatment of chickens in the foetal period.
Gonadotropin or TSH treatment of the chick embryo influences the T4 production of the one-month-old animal if TSH is given on a second occasion. Hormone treatment on the 8th day of life was ineffective, while previous treatment of the 12-day-old embryo resulted in a significantly more pronounced elevation of serum T4 level compared to the control when provoked by TSH in the one-month-old animal and a significant reduction in the animals subjected to gonadotropin pretreatment.
D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000494:pharmacology*; D011956:Receptors, Cell Surface / Q000187:drug effects*; D011988:Receptors, Thyroid Hormone; D013972:Thyrotropin / Q000494:pharmacology*; D013974:Thyroxine / Q000097:blood
D006065:Gonadotropins, Pituitary; D011956:Receptors, Cell Surface; D011988:Receptors, Thyroid Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013974:Thyroxine