The cytochromes c: paradigms for chemical recognition.
The cytochromes c include subgroups which present a variety of redox functions based on well-defined changes in the basic three-dimensional structure exemplified by the mitochondrial and certain bacterial forms, in particular cytochromes c2. These proteins exhibit overlapping functionality and a graded sequence of structures which provide paradigms well suited for clarification of recognition mechanisms. The character and distribution of cytochromes c will be discussed and approaches to relatedness of structure and function will be described, based on kinetic analyses of cross reactivities of cytochromes c2 with mitochondrial cytochrome c oxidase.
D000818:Animals; D001419:Bacteria / Q000378:metabolism; D001665:Binding Sites; D003574:Cytochrome c Group / Q000378:metabolism*; D045362:Cytochromes c2; D003576:Electron Transport Complex IV / Q000378:metabolism; D006736:Horses; D007700:Kinetics; D008928:Mitochondria / Q000378:metabolism; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011485:Protein Binding; D011487:Protein Conformation; D013045:Species Specificity; D014413:Tuna
D003574:Cytochrome c Group; D045362:Cytochromes c2; D003576:Electron Transport Complex IV