Fatal herpes simplex encephalitis with demonstration of virus in the olfactory pathway.
A fatal case of herpes simplex encephalitis contained viruses within the olfactory pathway but not in the trigeminal ganglia. This finding supports the theory that the olfactory nerves are the portal of entry in adult herpes simplex encephalitis.
D004660:Encephalitis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009832:Olfactory Nerve / Q000382:microbiology*; D018139:Simplexvirus / Q000302:isolation & purification*; D013702:Temporal Lobe / Q000382:microbiology