title: [Aujeszky's disease: maternal immunity of piglets born of sows inoculated with various vaccines (author's transl)].
abstract: Studies on the maternal state of immunity were done in 4-10 week-old piglets born of vaccinated sows free from Aujeszky's disease. The sows were inoculated with three different vaccines: two live vaccines (Aescovac Aujeszky) and the MK25 vaccine) and an inactivated vaccine (Geskyvac). The maternal state of immunity of the piglets was assessed from the titre of the virus-neutralizing (VN) antibodies in the blood. To do so, samples were taken from 300-400 4-10-week-old piglets per vaccine inoculated in the sow. At the same time, the VN titre of the blood of the sow was determined. The VN titres were highest in those sows which were vaccinated with Geskyvac. There was an obvious correlation between the VN titre of the sow and the maternal VN titres of the piglets. As a result, the maternal state of immunity in the sows vaccinated with Geskyvac also was highest. The value of the maternal VN titres in the assessment of maternal immunity was tested by exposing 28-37-day-old piglets showing various maternal VN titres to intracerebral challenge with 2000 TCID50 of Aujeszky disease virus (Van Doorn strain). Piglets showing VN titres higher than 1:8 were usually found to be immune against this challenge.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D011558:Herpesvirus 1, Suid / Q000276:immunology; D007112:Immunity, Maternally-Acquired; D011557:Pseudorabies / Q000276:immunology* / Q000517:prevention & control; D013552:Swine / Q000276:immunology*; D014765:Viral Vaccines / Q000627:therapeutic use
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Ziekte van Aujeszky: maternale immuniteit van biggen, geboren uit met verschillende entstoffen geënte zeugen.