[Transport of H+ in mitochondria induced by the uptake of sulfite, sulfate and thiosulfate].
The addition of sulphite to rat-liver mitochondria (RLM) causes an uptake of H+ that is unaffected by NEM and butylmalonate. The uptake of H+ induced by sulphate or thiosulphate is abolished by NEM and butylmalonate in freshly isolated RLM, whereas it is inhibited only by butylmalonate in sulphite-pretreated mitochondria. The data suggest that sulphite is cotransported with H+, whereas the movement of H+ associated to the uptake of sulphate or thiosulphate by RLM is mediated by either phosphate or sulphite.
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D005033:Ethylmaleimide / Q000494:pharmacology; D008314:Malonates / Q000494:pharmacology; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D011522:Protons; D051381:Rats; D013431:Sulfates / Q000378:metabolism*; D013447:Sulfites / Q000378:metabolism*; D013885:Thiosulfates / Q000378:metabolism*
D008314:Malonates; D011522:Protons; D013431:Sulfates; D013447:Sulfites; D013885:Thiosulfates; C027734:n-butylmalonic acid; D005033:Ethylmaleimide
Trasporto di h+ nei mitocondri indotto dall'aggiunta di solfito, solfato e tiosolfato.