title: Determination of liver and spleen perfusion by quantitative sequential scintigraphy: results in normal subjects and in patients with portal hypertension.
abstract: Quantitative sequential hepatosplenic scintigraphy was performed to determine the arterial and portal components of the total liver circulation in 135 patients (no liver disease in 20, liver cirrhosis and portal ;hypertension in 115). Portal circulation in healthy patients is calculated to be 70.4 +/- 6.2% of the total liver blood flow, whereas patients with portal hypertension showed a clear reduction of portal perfusion to 20.2 +/- 10.9%. Thirteen of 20 patients having portosystemic shunt surgery showed no portal perfusion. This new, noninvasive diagnostic technique yields vital information particularly useful in ;the surgical evaluation of portal hypertension. Other indications are also discussed.
mesh_terms: D000792:Angiography; D006801:Humans; D006975:Hypertension, Portal / Q000000981:diagnostic imaging* / Q000473:pathology; D008099:Liver / Q000098:blood supply / Q000000981:diagnostic imaging*; D010477:Perfusion; D011168:Portal System / Q000000981:diagnostic imaging; D011170:Portasystemic Shunt, Surgical; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013670:Sodium Pertechnetate Tc 99m; D013154:Spleen / Q000000981:diagnostic imaging*; D013667:Technetium
chemical_list: D013667:Technetium; D013670:Sodium Pertechnetate Tc 99m