[Features of metabolism in subcellular fractions of the motor cortex during restoration of visual nerve impulses].
Experimental data are obtained on cytochromoxidase (CO), acetylcholinesterase (AchE), MAO and ATPase activities in subfractions of synaptosomes and cellular mitochondria from the rabbit motor cortex following long-term visual deprivation. The first stage is characterized by elevated protein content and activation of enzymatic systems except K+; Na+--ATPase and CO. The tendency towards normalizing of protein content and activity of enzymes, particularly AchE and MAO occurred within 4 weeks. These data show that changes of enzymatic activity in subcellular components of the motor cortex following the sensory deprivation, are reversible but the process of neuronal recompensation in the integrative--starting system is complex and demands a longer time than in visual one.
D000110:Acetylcholinesterase / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D003576:Electron Transport Complex IV / Q000378:metabolism; D008274:Magnesium / Q000494:pharmacology; D008928:Mitochondria / Q000378:metabolism; D008995:Monoamine Oxidase / Q000378:metabolism; D009044:Motor Cortex / Q000378:metabolism*; D011817:Rabbits; D012683:Sensory Deprivation; D013574:Synaptosomes / Q000378:metabolism; D014785:Vision, Ocular / Q000502:physiology*
D008995:Monoamine Oxidase; D003576:Electron Transport Complex IV; D000110:Acetylcholinesterase; D000251:Adenosine Triphosphatases; D008274:Magnesium
Osobennosti obmena v subkletochnykh fraktsiiakh dvigatel'noĭ oblasti kory bol'shikh polushariĭ pri vosstanovlenii zritel'noĭ impul'satsii.