[An outbreak type A hepatitis in a family group living in a village near Parma. Epidemiologic evaluation and prophylaxis (author's transl)].
The most recent data concerning the characteristics of hepatitis A virus, as well as epidemiology and prophylaxis of type A hepatitis are described. An epidemic of hepatitis A which occurred in a village near Parma is analysed. The diagnosis was based on the detection, by radioimmunoassay, of specific antibody to hepatitis A antigen (anti-HAV) at the beginning of the infection and during the convalescence. In addition the occurrence of high levels of specific immunoglobulins type M anti HAV, during the acute phase, was a further evidence of the diagnosis. The presence of other agents responsible for acute hepatitis, such as Cytomegalovirus and Epstein-Barr virus, has been excluded by laboratory examination.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D004196:Disease Outbreaks; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology*; D035922:Hepatitis A Antibodies; D006507:Hepatovirus; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007558:Italy; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay
D000914:Antibodies, Viral; D035922:Hepatitis A Antibodies; D007075:Immunoglobulin M
Analisi di un focolaio epidemico familiare di epatite A nella provincia di Parma. Considerazioni di epidemiologia e profilassi.