title: Lipids and membrane function: implications in arrhythmias.
abstract: Increasing attention is being devoted to the relevance of lipid-membrane interactions to arrhythmias and their therapy. Particular emphasis is placed on alterations of transmembrane ion transport that can result from closure of protein channels, perhaps mediated by chemically induced changes in the phospholipid membrane bilayer. Such alterations may underlie antiarrhythmic drug actions.
mesh_terms: D000200:Action Potentials; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D002462:Cell Membrane / Q000503:physiopathology; D003327:Coronary Disease / Q000503:physiopathology; D004594:Electrophysiology; D006321:Heart / Q000503:physiopathology; D006801:Humans; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology; D008051:Lipid Bilayers / Q000502:physiology*
chemical_list: D000889:Anti-Arrhythmia Agents; D007473:Ion Channels; D008051:Lipid Bilayers