[Nitrite reduction by NADH, catalyzed by the nitrite reductase of Pseudomonas aeruginosa].
Reduction of nitrite by NADH catalyzed by Pseudomonas aeruginosa nitrite reductase is inhibited by a high concentration of nitric oxide NO. Contrary to what is currently admitted, we find that the nitrite reduction proceeds to the nitrogen monoxide N2O stage. EPR spectra show that, during the catalytic cycle, the enzyme forms specific Fe2+-NO heminic complexes.
D002384:Catalysis; D055598:Chemical Phenomena; D002621:Chemistry; D004578:Electron Spin Resonance Spectroscopy; D009243:NAD / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D009569:Nitric Oxide / Q000494:pharmacology; D009572:Nitrite Reductases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009573:Nitrites / Q000378:metabolism*; D010084:Oxidation-Reduction; D011550:Pseudomonas aeruginosa / Q000201:enzymology*
D009573:Nitrites; D009243:NAD; D009569:Nitric Oxide; D009247:NADH, NADPH Oxidoreductases; D009572:Nitrite Reductases
Etude de la réduction du nitrite par la NADH, catalysée par la nitrite réductase de Pseudomonas aeruginosa.