Persistence of herpes simplex virus (HSV) infection in ganglia and peripheral tissues of guinea pigs.
HSV infections in guinea pigs are shown to persist independently in dorsal root ganglia and skin at the site of initial inoculation. The same may also hold for ganglia and vagina after genital infections. Evidence is presented that the state of persistent virus might be different in ganglia and peripheral tissue.
D000818:Animals; D003714:Denervation; D005260:Female; D005724:Ganglia / Q000382:microbiology*; D005727:Ganglia, Spinal / Q000382:microbiology; D006168:Guinea Pigs; D006561:Herpes Simplex / Q000382:microbiology*; D010746:Phosphonoacetic Acid / Q000494:pharmacology; D018139:Simplexvirus / Q000302:isolation & purification*; D012867:Skin / Q000382:microbiology*; D013997:Time Factors; D014621:Vagina / Q000382:microbiology*
D010746:Phosphonoacetic Acid