[On the influence of hormones on genome in aging (author's transl)].
The hormonal uptake, binding and responsiveness are decreased with few exceptions in the target organs of old animals. Qualitative changes of chromatin and changed receptor concentration and affinity are considered as causes.
D000368:Aged; D000375:Aging; D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000378:metabolism; D051379:Mice; D011817:Rabbits; D051381:Rats; D011956:Receptors, Cell Surface / Q000378:metabolism*; D013963:Thyroid Hormones / Q000378:metabolism
D002395:Catecholamines; D005938:Glucocorticoids; D006728:Hormones; D007328:Insulin; D011956:Receptors, Cell Surface; D013963:Thyroid Hormones
Zur Molekularbiologie des Alterns. 18. Mitteilung: Der Einfluss von Hormonen auf das Genom im Alter.