[The behaviour of endocrinal parameters under prophylaxis of hyaline membrane disease with glucocorticoids (author's transl)].
Prevention of hyaline membrane disease with glucocorticoids produces suppression of the hypopituitary-adrenocortical axis of the mother as well as of the foetus. The extent of the suppression is significantly higher under medication with the 9 alpha-fluorinated preparations, betamethasone and dexamethasone, than under medication with 16-methyleneprednisolone. Increases in the concentration levels of the mineralocorticoid DOC are to be expected in 37% to 50% of the patients, depending on the administered corticoid. The percentage of increase is 150% under 16-methyleneprednisolone and 220% under betamethasone and dexamethasone.
D000305:Adrenal Cortex Hormones / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D003900:Desoxycorticosterone / Q000097:blood; D004964:Estriol / Q000097:blood*; D005260:Female; D005938:Glucocorticoids / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D006819:Hyaline Membrane Disease / Q000517:prevention & control*; D006854:Hydrocortisone / Q000097:blood; D007231:Infant, Newborn; D011247:Pregnancy
D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids; D003900:Desoxycorticosterone; D000324:Adrenocorticotropic Hormone; D004964:Estriol; D006854:Hydrocortisone
Das Verhalten endocriner Parameter unter der Membranprophylaxe mit Glucocorticoiden.