[Metabolism of erythrocyte chalone in vitro].
It has been shown that erythrocytic chalone was bound to the surface of mouse myelokaryocytes after one minute, penetrated them after 30 minutes, disintegrated and excreted in the form of low-molecular mass compounds after 4 hours of incubation. The cells treated with erythrocytic chalone or trypsin are not capable to respond to the repeated action of chalone over 2 hours, which seems likely to be related to the lack of receptor resynthesis during the period under consideration.
D000818:Animals; D001853:Bone Marrow / Q000378:metabolism; D002478:Cells, Cultured; D004912:Erythrocytes / Q000378:metabolism*; D004921:Erythropoietin / Q000378:metabolism / Q000494:pharmacology; D006131:Growth Inhibitors / Q000097:blood*; D051379:Mice; D011956:Receptors, Cell Surface / Q000378:metabolism; D018000:Receptors, Peptide; D014357:Trypsin / Q000494:pharmacology
D006131:Growth Inhibitors; D011956:Receptors, Cell Surface; D018000:Receptors, Peptide; C031544:chalone receptor; D004921:Erythropoietin; D014357:Trypsin
O metabolizme éritrotsitarnogo keĭlona in vitro.