Further evidence that desensitization of beta-adrenergic-sensitive adenylate cyclase proceeds in two steps. Modification of the coupling and loss of beta-adrenergic receptors.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002460:Cell Line; D003513:Cycloheximide / Q000494:pharmacology; D004082:Dihydroalprenolol / Q000378:metabolism; D004789:Enzyme Activation; D005910:Glioma; D007545:Isoproterenol / Q000494:pharmacology*; D007700:Kinetics; D008433:Mathematics; D051379:Mice; D011458:Prostaglandins E / Q000494:pharmacology; D011691:Puromycin / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000378:metabolism*; D013696:Temperature
D011458:Prostaglandins E; D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; D011691:Puromycin; D004082:Dihydroalprenolol; D003513:Cycloheximide; D000262:Adenylyl Cyclases; D007545:Isoproterenol