[Some mechanisms of papaverine and trental action in patients with acute arterial obstruction].
A comparative study of the effect of trental and papaverin upon the systemic and peripheral blood circulation was carried out in patients with acute arterial obstruction of the lower extremities due to embolism. The advantage of trental over papaverin is shown convincingly. Injection of papaverin results in the improvement in 38% of cases. Trental improved microcirculation in the diseased extremity in all the examined patients without substantial changes in the regional microhemodynamics and systemic circulation.
D000208:Acute Disease; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000368:Aged; D001132:Arm / Q000098:blood supply*; D000242:Cyclic AMP / Q000097:blood; D004617:Embolism / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D010208:Papaverine / Q000627:therapeutic use*; D010431:Pentoxifylline / Q000627:therapeutic use*; D013805:Theobromine / Q000031:analogs & derivatives*
D000324:Adrenocorticotropic Hormone; D010208:Papaverine; D000242:Cyclic AMP; D013805:Theobromine; D010431:Pentoxifylline; D006854:Hydrocortisone
O nekotorykh mekhanizmakh deĭstviia papaverina i trentala u bol'nykh s ostroĭ arterial'noĭ neprokhodimost'ii.