title: Progressive multifocal leukoencephalopathy: immunofluorescent demonstration of simian virus 40 antigen in CSF cells and response to cytarabine therapy.
abstract: We report an instance of progressive multifocal leukoencephalopathy in which cytarabine administration was successful as demonstrated by clinical course and follow-up computerized tomography studies. In this case, simian virus 40 (SV40) antigen was demonstrated in CSF cells by the indirect immunofluorescence technique.
mesh_terms: D000328:Adult; D000956:Antigens, Viral / Q000134:cerebrospinal fluid; D003561:Cytarabine / Q000627:therapeutic use*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D013539:Simian virus 40 / Q000276:immunology; D014740:Vidarabine / Q000627:therapeutic use
chemical_list: D000956:Antigens, Viral; D003561:Cytarabine; D014740:Vidarabine