title: Glycogen synthesis by cell-free extracts from the dimorphic yeast Candida albicans.
abstract: A particulate glucosyltransferase prepared from budding and filamentous cultures of Candida albicans used uridine diphosphate glucose as sole glucosyl donor in a reaction (measured by following the incorporation of [14C]-glucose from UDP [14C]-glucose into polymer) stimulated by glucose-6-phosphate and inhibited by adenosine triphosphate and guanosine triphosphate. The radiolabelled reaction product was solubilized by alpha-amylase, and, on oxidation with periodate followed by reduction with borohydride and acid hydrolysis, yielded erythritol and glycerol in the ratio of 4 to 1. The radiolabelled glucosyl residues were attached to an endogenous acceptor of high molecular weight.
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates / Q000494:pharmacology; D005964:Glucosyltransferases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006003:Glycogen / Q000096:biosynthesis*; D006006:Glycogen Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000494:pharmacology; D008565:Membrane Proteins; D029702:Schizosaccharomyces pombe Proteins
chemical_list: D005958:Glucosephosphates; D008565:Membrane Proteins; D029702:Schizosaccharomyces pombe Proteins; D019298:Glucose-6-Phosphate; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D006003:Glycogen; D005964:Glucosyltransferases; D006006:Glycogen Synthase; C020570:1,3-beta-glucan synthase