[Kidney and osseous responsiveness to PTH in a case of pseudohypoparathyroidism (author's transl)].
A case of pseudohypoparathyroidism is described, finding in addition to the typical clinical data described in the literature an all almost total atrophy of the minor lips and clitoris, a perforated hymen and a "paradoxical" increase of convulsions with anticomicial treatment. Study of response of urinary phosphates and AMPc to PTH, was negative (Drezner type I). Osseous response to PTH was negative (Frame type I pseudohypoparathyroidism). Pathogenic possibilities are discussed.
D000927:Anticonvulsants / Q000494:pharmacology; D001842:Bone and Bones / Q000187:drug effects; D002675:Child, Preschool; D000242:Cyclic AMP / Q000378:metabolism; D004351:Drug Resistance; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000378:metabolism; D007668:Kidney / Q000187:drug effects; D010281:Parathyroid Hormone / Q000627:therapeutic use*; D010710:Phosphates / Q000652:urine; D011547:Pseudohypoparathyroidism / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism; D012640:Seizures / Q000188:drug therapy
D000927:Anticonvulsants; D010281:Parathyroid Hormone; D010710:Phosphates; D000242:Cyclic AMP
Resistencia renal y ósea a la PTH en un caso de pseudohipoparatiroidismo.