[Intracellular cyclic AMP in vesicular stomatitis or Sendaï virus infected cells (author's transl)].
In KB cells, MRC5 and adult skin fibroblasts infected by low doses of Sendaï virus, intracellular cyclic AMP levels rose and fell in the first hours following infection, then remained lower than basal level during at least 2 days in KB cells and adult skin fibroblasts. When compared to other viruses or cAMP inducers previously described, this effect appeared specific of Sendaï virus. Mechanisms and roles of cAMP variations are discussed. VSV-infected KB cells showed slightly decreased cAMP levels during the first hours following infection.
D002478:Cells, Cultured; D000242:Cyclic AMP / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D010222:Parainfluenza Virus 1, Human / Q000502:physiology*; D011953:Receptors, Cyclic AMP / Q000378:metabolism; D014721:Vesicular stomatitis Indiana virus / Q000502:physiology*
D011953:Receptors, Cyclic AMP; D000242:Cyclic AMP
Variations des concentrations de cAMP intracellulaire de différents types de cellules après infection par le virus Sendaï ou le virus de la stomatite vésiculeuse.