title: [Tumour induction with alkyl-nitrosoureas in ribbed newts (Pleurodeles waltlii) (author's transl)].
abstract: A search for animal models in the field of environmental carcinogenesis was performed. 50 adult ribbed newts were exposed to methyl- and ethylnitrosoureas. In 10 animals fibro- and hemangiosarcomas, nephroblastomas and a cavernous hemangioma were induced. No tumors of the nervous system occurred.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005038:Ethylnitrosourea; D005260:Female; D005354:Fibrosarcoma / Q000139:chemically induced; D006391:Hemangioma / Q000139:chemically induced; D006394:Hemangiosarcoma / Q000139:chemically induced; D008297:Male; D008770:Methylnitrosourea; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009607:Nitrosourea Compounds; D010999:Pleurodeles; D012455:Salamandridae; D012513:Sarcoma, Experimental / Q000139:chemically induced; D009396:Wilms Tumor / Q000139:chemically induced
chemical_list: D009607:Nitrosourea Compounds; D008770:Methylnitrosourea; D005038:Ethylnitrosourea
vernacular_title: Tumorinduktion bei spanischen Rippenmolchen (Pleurodeles waltlii) durch Alkylnitrosoharnstoffe.