Lowering plasma cholesterol by raising LDL receptors.
D000818:Animals; D002784:Cholesterol / Q000097:blood* / Q000378:metabolism; D004285:Dogs; D006579:Heterozygote; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000188:drug therapy / Q000235:genetics; D008077:Lipoproteins, LDL / Q000097:blood* / Q000378:metabolism; D008148:Lovastatin / Q000031:analogs & derivatives*; D008875:Middle Aged; D009281:Naphthalenes / Q000494:pharmacology* / Q000627:therapeutic use; D011956:Receptors, Cell Surface; D011973:Receptors, LDL
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008077:Lipoproteins, LDL; D009281:Naphthalenes; D011956:Receptors, Cell Surface; D011973:Receptors, LDL; C012258:mevastatin; D002784:Cholesterol; D008148:Lovastatin