Chromosome counts of 90Sr-induced osteosarcomas in mice.  II. Variation of the chromosome counts of slow and fast growing tumours in hyper- and nonhyperimmunized hosts.
Highly inbred CBA mice were used. The registration of chromosome abnormalities was limited to numerical deviations and the occurrence of metacentric chromosomes. By separate serial transplantation from a 90Sr-induced osteosarcoma two parallel transfer series (B and b) were established. From these series transplantation was also performed to hyperimmunized hosts B (Hi) and b (Hi). Besides differences in mean outgrowth period between B-and b-generations, a variation in chromosome pattern was observed. However, this variation should not be evaluated as a typical chromosomal progression of fast and slow growing tumour series.
D000782:Aneuploidy; D000818:Animals; D007114:Immunization; D051379:Mice; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000235:genetics / Q000276:immunology; D009381:Neoplasms, Radiation-Induced / Q000235:genetics* / Q000276:immunology; D012516:Osteosarcoma / Q000235:genetics* / Q000276:immunology; D013326:Strontium Radioisotopes / Q000009:adverse effects
D013326:Strontium Radioisotopes