Transfection by DNAs of avian erythroblastosis virus and avian myelocytomatosis virus strain MC29.
Chicken embryo fibroblasts and NIH 3T3 mouse cells were transformable by DNAs of chicken cells infected with avian myelocytomatosis virus strain MC29 or with avian erythroblastosis virus. Transfection of chicken cells appeared to require replication of MC29 or avian erythroblastosis virus in the presence of a nontransforming helper virus. In contrast, NIH 3T3 cells transformed by MC29 or avian erythroblastosis virus DNA contained only replication-defective transforming virus genomes.
D001355:Alpharetrovirus / Q000235:genetics* / Q000254:growth & development; D000818:Animals; D001354:Avian Leukosis Virus / Q000235:genetics* / Q000254:growth & development; D002460:Cell Line; D002472:Cell Transformation, Viral; D002642:Chick Embryo; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D051379:Mice; D014162:Transfection
D004279:DNA, Viral