[Ultrastructural characteristics of seminoma and embryonal cancer of the testis].
Twenty-three germ cell tumors of the testis were investigated. Electron microscopic examinations of four seminomas and four embryonal carcinomas revealed cells of different degrees of differentiation. Tumor cells of seminoma acquired the ultrastructural features of the cells of developing seminal epithelium whereas in embryonal carcinoma there was a pronounced tendency of formation of mature tissues of teratoma. These data confirmed the cytogenetic resemblance of seminoma and embryonal carcinoma originating from the seminal epithelium which could undergo malignization at different stages of development. The latter predetermined diverse direction of differentiation in germ cell tumors of the testis.
D000293:Adolescent; D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000648:ultrastructure; D004407:Dysgerminoma / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000648:ultrastructure*; D013724:Teratoma / Q000648:ultrastructure; D013736:Testicular Neoplasms / Q000648:ultrastructure*
Ul'trastrukturnaia kharakteristika seminomy i émbrional'nogo raka iaichka.