[Changes in collagen structure under the influence of mechanical dispersion].
Air-dry collagen isolated from cattle retinal layer by means of alkaline-salt treatment was crushed in a laboratory vibro-mill at 80-150 degrees K. Mechanochemical transformations were studied by means of viscosimetry, polarimetry, ESR-spectroscopy and electron microscopy. Mechanical tensions induce breakage of covalent bonds of polypeptide chains, accompanied by a decrease of protein molecular mass, and of lateral interactions, which results in loosening of collagen structure and partial denaturation.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003094:Collagen; D004578:Electron Spin Resonance Spectroscopy; D008854:Microscopy, Electron; D008970:Molecular Weight; D011487:Protein Conformation; D014783:Viscosity
D003094:Collagen
Izmenenie struktury kollagena pod vliianiem mekhanicheskogo dispergirovaniia.