[Gamma-heavy chain disease with autoimmune abnormalities and peripheral neuropathy (author's transl)].
The authors report the case of a 72 year old woman affected by gamma heavy chain disease in whom the heavy chain was detected in the serum and the urine as well. Further study of the paraprotein showed that it belonged to the gamma 1 subclass. This observation was unusual because of the presence of a 15 year-long peripheral neuropathy and the existence of various auto-antibodies, especially intrinsic factor antibody.
D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D006362:Heavy Chain Disease / Q000150:complications* / Q000276:immunology; D006801:Humans; D007122:Immunoelectrophoresis; D007142:Immunoglobulin gamma-Chains; D007437:Intrinsic Factor / Q000276:immunology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000276:immunology
D001323:Autoantibodies; D007142:Immunoglobulin gamma-Chains; D007437:Intrinsic Factor
Maladie des chaînes lourdes gamma avec auto-anticorps multiples et neuropathie périphérique.