title: Correlation of 99mTc-pyrophosphate myocardial accumulation with left ventricular wall motion abnormalities.
abstract: Reports have indicated that myocardial accumulation of 99mTc-pyrophosphate occurs in the absence of a recent myocardial infarction. An attempt was made to determine if myocardial accumulation, in the absence of a recent infarction, may be associated with left ventricular wall motion abnormalities. 51 patients undergoing elective left ventriculography had 99mTc-pyrophosphate cardiac scans 24-28 h prior to the procedure. 33 (33/51) patients had myocardial accumulation; all 33 had left ventrcular wall motion abnormalities. Localized myocardial accumulation occurred in 21 (21/33) patients; 19 of the 21 had localized left ventricular wall motion abnormalities corresponding to the area of myocardial accumulation. 12 (12/33) patients had diffuse myocardial accumulation; 4 had diffuse left ventricular hypokinesis and 8 had localized myocardial dysfunction. 18 (18/51) patients had no myocardial accumulation of the radionuclide; 9 had normal wall motion in all areas and 9 had localized dysfunction. The data strongly suggest that myocardial accumulation of 99mTc-pyrophosphate in the absence of a recent myocardial infarction is associated with a left ventricular wall motion abnormality.
mesh_terms: D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000000981:diagnostic imaging; D011756:Diphosphates; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006322:Heart Aneurysm / Q000000981:diagnostic imaging; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000175:diagnosis / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011859:Radiography; D011877:Radionuclide Imaging; D013667:Technetium
chemical_list: D011756:Diphosphates; D013667:Technetium