Procainamide and peripheral neuropathy.
I have described a case of procainamide-induced peripheral neuropathy with a complete resolution after withdrawal of the drug. Extremely close observation is suggested, and if paresthesia and/or polyarthralgias develop, this agent must be withdrawn. The SLE-like syndrome inducted by procainamide completely resolves on withdrawal of the drug. N-acetylprocainamide (NAPA) should probably be prescribed in preference to procainamide.
D000368:Aged; D005260:Female; D006801:Humans; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D011342:Procainamide / Q000009:adverse effects*
D011342:Procainamide