[Effect of a tortoise spleen extract on the functional state of liver mitochondria in irradiated mice].
A study was made of the effect of a drug prepared from a spleen extract of Testudo horsfieldi on energy metabolism and lipid composition of liver mitochondria of irradiated mice (2.06 X 10(-1) C/kg). It was shown that the decompensated low-energy state of liver mitochondria of the exposed mice was changed into the state of the compensated low-energy shift: the physicochemical properties of lipid microenvironment of mitochondria proteins were partially restored.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D050356:Lipid Metabolism; D008297:Male; D051379:Mice; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000188:drug therapy*; D013154:Spleen / Q000502:physiology*; D013385:Succinate Dehydrogenase / Q000378:metabolism; D014020:Tissue Extracts / Q000627:therapeutic use*; D014426:Turtles / Q000502:physiology*
D014020:Tissue Extracts; D013385:Succinate Dehydrogenase; D000251:Adenosine Triphosphatases
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