title: Long lasting amplification and deformation of thyroid receptors after thyrotropin (TSH) and gonadotropin (GTH) treatment of chickens in the foetal period.
abstract: Gonadotropin or TSH treatment of the chick embryo influences the T4 production of the one-month-old animal if TSH is given on a second occasion. Hormone treatment on the 8th day of life was ineffective, while previous treatment of the 12-day-old embryo resulted in a significantly more pronounced elevation of serum T4 level compared to the control when provoked by TSH in the one-month-old animal and a significant reduction in the animals subjected to gonadotropin pretreatment.
mesh_terms: D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000494:pharmacology*; D011956:Receptors, Cell Surface / Q000187:drug effects*; D011988:Receptors, Thyroid Hormone; D013972:Thyrotropin / Q000494:pharmacology*; D013974:Thyroxine / Q000097:blood
chemical_list: D006065:Gonadotropins, Pituitary; D011956:Receptors, Cell Surface; D011988:Receptors, Thyroid Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013974:Thyroxine