[Clinical aspects of the pathology of neuromuscular transmission].
On the basis of analyzing clinical reports, the results of the author's own studies, and respective information published in literature, principal problems concerning the clinical course, the mechanism of development, the methods of treatment and organization of the therapeutic and prophylactic aid to patients with neuromuscular transmission pathologies are discussed. The main myasthenic syndromes, as well as problems of myasthenia differential diagnosis are described. A question on the role of autoimmune disturbances in the formation of muscular disturbances in cases of a neuromuscular transmission pathology is raised. Data characterizing the role of anticholinesterase drugs, hormones, surgical and radiotherapeutic methods in the treatment of myasthenia and myasthenic disturbances are presented.
D000110:Acetylcholinesterase / Q000172:deficiency; D001259:Ataxia / Q000175:diagnosis; D001323:Autoantibodies; D018288:Carcinoma, Small Cell / Q000175:diagnosis; D002800:Cholinesterase Inhibitors; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000628:therapy; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D009469:Neuromuscular Junction; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis; D009435:Synaptic Transmission; D013577:Syndrome; D013934:Thymectomy
D001323:Autoantibodies; D002800:Cholinesterase Inhibitors; D000110:Acetylcholinesterase
Klinicheskie aspekty patologii nervno-myshechnoĭ peredachi.