[Promoting effect of portacaval anastomosis in experimental hepatic carcinogenesis].
A promoting effect of portocaval anastomosis in a triphasic model of rat hepatocarcinogenesis is demonstrated since after initiation and selection premalignant lesions and hepatocellular carcinomas increase. This demonstrates that chronic administration of an exogenous compound is not the only way to promote cancer development.
D015073:2-Acetylaminofluorene; D000818:Animals; D002251:Carbon Tetrachloride; D004052:Diethylnitrosamine; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000209:etiology*; D008297:Male; D011167:Portacaval Shunt, Surgical / Q000009:adverse effects*; D051381:Rats; D011919:Rats, Inbred Strains
D004052:Diethylnitrosamine; D015073:2-Acetylaminofluorene; D002251:Carbon Tetrachloride
Effet promoteur de l'anastomose portocave dans l'hépatocarcinogenèse expérimentale.