title: Variations in levels of cyclic AMP and GMP in the thymus, spleen and mesenteric lymph node of rats after the induction of adjuvant arthritis.
abstract: The development of adjuvant arthritis induced important modifications in intracellular levels of cyclic AMP and GMP in primary and secondary lymphoid organs: a continuous decrease in cyclic AMP and a biphasic increase in the level of cyclic GMP which correlate well with the onset of the acute phase and the systemization of the disease.
mesh_terms: D000818:Animals; D001168:Arthritis / Q000378:metabolism*; D001169:Arthritis, Experimental / Q000378:metabolism*; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D008198:Lymph Nodes / Q000032:analysis; D008643:Mesentery / Q000032:analysis; D051381:Rats; D013154:Spleen / Q000032:analysis; D013950:Thymus Gland / Q000032:analysis
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP