Characterization of T cell surface glycoproteins T 1 and T 3 present on all human peripheral T lymphocytes and functionally mature thymocytes.
The monoclonal antibodies, anti-T1 and anti-T3, both react with all human peripheral thymus-derived lymphocytes and with 10% of thymocytes; each, however, recognizes different cell surface structures. It was determined that the target antigen of anti-T is a 69 000 molecular weight cell surface glycoprotein and that the T3 antigen is a 19 000 mol. wt. glycoprotein.
D001894:Borohydrides / Q000494:pharmacology; D002454:Cell Differentiation; D003432:Cross-Linking Reagents / Q000494:pharmacology; D005692:Galactose Oxidase / Q000494:pharmacology; D006023:Glycoproteins / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D008565:Membrane Proteins / Q000276:immunology*; D008970:Molecular Weight; D009439:Neuraminidase / Q000494:pharmacology; D010504:Periodic Acid / Q000494:pharmacology; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*
D001894:Borohydrides; D003432:Cross-Linking Reagents; D006023:Glycoproteins; D008565:Membrane Proteins; D010504:Periodic Acid; D005692:Galactose Oxidase; D009439:Neuraminidase