Simultaneous primary oat cell carcinoma (apudoma) and squamous cell carcinoma of the hypopharynx.
The first case of the association of oat cell carcinoma and squamous carcinoma of the hypopharynx occurring in a 57-year-old man is reported. The patient underwent total laryngopharyngectomy with radical neck dissection, but died 3 1/2 months after diagnosis with multiple bone metastases of the ribs and vertebrae. The histogenesis of oat cell carcinoma in the hypopharynx is discussed, together with the therapeutic approach for the simultaneous occurrence of two primary malignant neoplasms in the same organ.
D018288:Carcinoma, Small Cell / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D006801:Humans; D007013:Hypopharynx; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010610:Pharyngeal Neoplasms / Q000473:pathology*