Augmentation of vincristine neurotoxicity by irradiation of peripheral nerves.
Four cases are presented in which children receiving radiation therapy and combination chemotherapy had unilateral severe and prolonged neurotoxic effects. Augmentation of vincristine neurotoxicity by irradiation of peripheral nerves is suggested.
D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D014750:Vincristine / Q000009:adverse effects*
D014750:Vincristine