Nuclear inclusions in oculopharyngeal dystrophy.
The ultrastructural examination of skeletal muscle biopsies of three typical cases of autosomal dominant inherited oculopharyngeal muscular dystrophy showed collections of tubular filaments (8.5 nm in diameter) within muscle fibre nuclei. These filaments appear to be a characteristic morphological feature of oculopharyngeal dystrophy.
D001706:Biopsy; D001763:Blepharoptosis / Q000473:pathology; D002467:Cell Nucleus / Q000648:ultrastructure*; D003680:Deglutition Disorders / Q000473:pathology; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009136:Muscular Dystrophies / Q000473:pathology*